SLC25A27

gene product
FLJ33552, UCP4
Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. Transcripts of this gene are only detected in brain tissue and are specifically modulated by various environmental conditions. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2011]
More gene data

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

  or   Clear
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Validated within AVI
Eligible for validation within AVI
75 antibodies from 20 providers.

Antibody properties

General

Applications

or Cancel
AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
4 antibodies
LifeSpan BioSciences, Inc.
12 antibodies
OriGene
3 antibodies
Acris Antibodies GmbH
2 antibodies
GeneTex
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Affinity Biosciences
1 antibody
antibodies-online
29 antibodies
Aviva Systems Biology
2 antibodies
Biorbyt
2 antibodies
Abnova Corporation
1 antibody
Atlas Antibodies
1 antibody
St John's Laboratory
3 antibodies
Invitrogen Antibodies
2 antibodies
Boster Biological Technology
1 antibody
NovoPro Bioscience Inc.
1 antibody
Creative Diagnostics
3 antibodies
MyBioSource
3 antibodies
United States Biological
1 antibody
Abgent
1 antibody