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- Antibody Data
- Antigen structure
- References [10]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
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- Product number
- 11114-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11114-1-AP, RRID:AB_2200201
- Product name
- TAP1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated TAP1 antibody (Cat. #11114-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Noncoding RNA 886 alleviates tumor cellular immunological rejection in host C57BL/C mice.
microRNA 125a Regulates MHC-I Expression on Esophageal Adenocarcinoma Cells, Associated With Suppression of Antitumor Immune Response and Poor Outcomes of Patients.
Expression of coproporphyrinogen oxidase is associated with detection of upper gastrointestinal carcinomas by 5-aminolevulinic acid-mediated photodynamic diagnosis.
Inducible TAP1 Negatively Regulates the Antiviral Innate Immune Response by Targeting the TAK1 Complex.
IRG1 increases MHC class I level in macrophages through STAT-TAP1 axis depending on NADPH oxidase mediated reactive oxygen species.
Characterization of the platelet granule proteome: evidence of the presence of MHC1 in alpha-granules.
Loss of heterozygosity at 6p21 and HLA class I expression in esophageal squamous cell carcinomas in China.
Methylation of the promoter of human leukocyte antigen class I in human esophageal squamous cell carcinoma and its histopathological characteristics.
The unfolded protein response (UPR)-activated transcription factor X-box-binding protein 1 (XBP1) induces microRNA-346 expression that targets the human antigen peptide transporter 1 (TAP1) mRNA and governs immune regulatory genes.
Down-regulation of the antigen processing machinery is linked to a loss of inflammatory response in colorectal cancer.
Ma H, Wang M, Zhou Y, Yang JJ, Wang LY, Yang RH, Wen MJ, Kong L
Cancer medicine 2020 Jul;9(14):5258-5271
Cancer medicine 2020 Jul;9(14):5258-5271
microRNA 125a Regulates MHC-I Expression on Esophageal Adenocarcinoma Cells, Associated With Suppression of Antitumor Immune Response and Poor Outcomes of Patients.
Mari L, Hoefnagel SJM, Zito D, van de Meent M, van Endert P, Calpe S, Sancho Serra MDC, Heemskerk MHM, van Laarhoven HWM, Hulshof MCCM, Gisbertz SS, Medema JP, van Berge Henegouwen MI, Meijer SL, Bergman JJGHM, Milano F, Krishnadath KK
Gastroenterology 2018 Sep;155(3):784-798
Gastroenterology 2018 Sep;155(3):784-798
Expression of coproporphyrinogen oxidase is associated with detection of upper gastrointestinal carcinomas by 5-aminolevulinic acid-mediated photodynamic diagnosis.
Ogihara K, Isomoto H, Kurumi H, Kanda T, Hashisako M, Tabata K, Ishii H, Ohnita K, Yamaguchi N, Akazawa Y, Matsushima K, Takeshima F, Kunizaki M, Hidaka S, Nanashima A, Fukuoka J, Nagayasu T, Nakao K
Photodiagnosis and photodynamic therapy 2017 Sep;19:15-21
Photodiagnosis and photodynamic therapy 2017 Sep;19:15-21
Inducible TAP1 Negatively Regulates the Antiviral Innate Immune Response by Targeting the TAK1 Complex.
Xia Z, Xu G, Yang X, Peng N, Zuo Q, Zhu S, Hao H, Liu S, Zhu Y
Journal of immunology (Baltimore, Md. : 1950) 2017 May 1;198(9):3690-3704
Journal of immunology (Baltimore, Md. : 1950) 2017 May 1;198(9):3690-3704
IRG1 increases MHC class I level in macrophages through STAT-TAP1 axis depending on NADPH oxidase mediated reactive oxygen species.
Liu X, Wu XP, Zhu XL, Li T, Liu Y
International immunopharmacology 2017 Jul;48:76-83
International immunopharmacology 2017 Jul;48:76-83
Characterization of the platelet granule proteome: evidence of the presence of MHC1 in alpha-granules.
Zufferey A, Schvartz D, Nolli S, Reny JL, Sanchez JC, Fontana P
Journal of proteomics 2014 Apr 14;101:130-40
Journal of proteomics 2014 Apr 14;101:130-40
Loss of heterozygosity at 6p21 and HLA class I expression in esophageal squamous cell carcinomas in China.
Zhao X, Sun Q, Tian H, Cong B, Jiang X, Peng C
Asian Pacific journal of cancer prevention : APJCP 2011;12(10):2741-5
Asian Pacific journal of cancer prevention : APJCP 2011;12(10):2741-5
Methylation of the promoter of human leukocyte antigen class I in human esophageal squamous cell carcinoma and its histopathological characteristics.
Qifeng S, Bo C, Xingtao J, Chuanliang P, Xiaogang Z
The Journal of thoracic and cardiovascular surgery 2011 Mar;141(3):808-14
The Journal of thoracic and cardiovascular surgery 2011 Mar;141(3):808-14
The unfolded protein response (UPR)-activated transcription factor X-box-binding protein 1 (XBP1) induces microRNA-346 expression that targets the human antigen peptide transporter 1 (TAP1) mRNA and governs immune regulatory genes.
Bartoszewski R, Brewer JW, Rab A, Crossman DK, Bartoszewska S, Kapoor N, Fuller C, Collawn JF, Bebok Z
The Journal of biological chemistry 2011 Dec 2;286(48):41862-41870
The Journal of biological chemistry 2011 Dec 2;286(48):41862-41870
Down-regulation of the antigen processing machinery is linked to a loss of inflammatory response in colorectal cancer.
Kasajima A, Sers C, Sasano H, Jöhrens K, Stenzinger A, Noske A, Buckendahl AC, Darb-Esfahani S, Müller BM, Budczies J, Lehman A, Dietel M, Denkert C, Weichert W
Human pathology 2010 Dec;41(12):1758-69
Human pathology 2010 Dec;41(12):1758-69
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HepG2 cells were subjected to SDS PAGE followed by western blot with 11114-1-AP( TAP1 Antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using TAP1 antibody 11114-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
