Antibody data
- Antibody Data
- Antigen structure
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- Product number
- CABT-B11585 - Provider product page
- Provider
- Creative Diagnostics
- Product name
- Mouse anti-Human TAP1 monoclonal antibody, clone 4E5
- Antibody type
- Monoclonal
- Description
- The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is involved in the pumping of degraded cytosolic peptides across the endoplasmic reticulum into the membrane-bound compartment where class I molecules assemble. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014]
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 4.00E+05
- Vial size
- 100 _g
- Storage
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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