Antibody data
- Antibody Data
- Antigen structure
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- Product number
- APR00102G - Provider product page
- Provider
- Leading Biology
- Product name
- MSH2 Antibody
- Antibody type
- Polyclonal
- Description
- DNA mismatch repair genes have been found to be associated with hereditary nonpolyposis colorectal cancer (HNPCC). Inherited mutations in the MSH2 were demonstrated at high frequency in HNPCC and were shown to be associated with microsatellite instability. The demonstration that 10 to 45% of pancreatic, gastric, breast, ovarian and small cell lung cancers also display microsatellite instability s μggests that DNA mismatch repair is not restricted to HNPCC tumors but is a common feature in tumor initiation or progression.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Storage
- Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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