Tissue expression
Cell line expression
MSH2
gene productCOCA1, HNPCC, HNPCC1
This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
Featured antibodies
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0 references | Polyclonal |
WB
ICC IP
IHC |