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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [7]
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- Product number
- MAB788 - Provider product page
- Provider
- R&D Systems
- Product name
- Anti-Human/Mouse/Rat GDF-8/Myostatin Monoclonal Antibody (Clone 84214)
- Antibody type
- Monoclonal
- Antigen
- Mouse myeloma cell line NS0-derived recombinant mouse GDF-8, Asn25-Ser376
- Description
- Protein A or G purified from hybridoma culture supernatant
- Reactivity
- Human, Mouse, Rat
- Host
- Rat
- Antigen sequence
O08689- Isotype
- IgG
- Vial size
- 500 µg
Submitted references The Use of Platelet-Rich and Platelet-Poor Plasma to Enhance Differentiation of Skeletal Myoblasts: Implications for the Use of Autologous Blood Products for Muscle Regeneration.
Differential muscle hypertrophy is associated with satellite cell numbers and Akt pathway activation following activin type IIB receptor inhibition in Mtm1 p.R69C mice.
Inhibition of activin receptor type IIB increases strength and lifespan in myotubularin-deficient mice.
High concentrations of HGF inhibit skeletal muscle satellite cell proliferation in vitro by inducing expression of myostatin: a possible mechanism for reestablishing satellite cell quiescence in vivo.
A new model for growth factor activation: type II receptors compete with the prodomain for BMP-7.
Targeting of bone morphogenetic protein growth factor complexes to fibrillin.
Gene silencing of myostatin in differentiation of chicken embryonic myoblasts by small interfering RNA.
Miroshnychenko O, Chang WT, Dragoo JL
The American journal of sports medicine 2017 Mar;45(4):945-953
The American journal of sports medicine 2017 Mar;45(4):945-953
Differential muscle hypertrophy is associated with satellite cell numbers and Akt pathway activation following activin type IIB receptor inhibition in Mtm1 p.R69C mice.
Lawlor MW, Viola MG, Meng H, Edelstein RV, Liu F, Yan K, Luna EJ, Lerch-Gaggl A, Hoffmann RG, Pierson CR, Buj-Bello A, Lachey JL, Pearsall S, Yang L, Hillard CJ, Beggs AH
The American journal of pathology 2014 Jun;184(6):1831-42
The American journal of pathology 2014 Jun;184(6):1831-42
Inhibition of activin receptor type IIB increases strength and lifespan in myotubularin-deficient mice.
Lawlor MW, Read BP, Edelstein R, Yang N, Pierson CR, Stein MJ, Wermer-Colan A, Buj-Bello A, Lachey JL, Seehra JS, Beggs AH
The American journal of pathology 2011 Feb;178(2):784-93
The American journal of pathology 2011 Feb;178(2):784-93
High concentrations of HGF inhibit skeletal muscle satellite cell proliferation in vitro by inducing expression of myostatin: a possible mechanism for reestablishing satellite cell quiescence in vivo.
Yamada M, Tatsumi R, Yamanouchi K, Hosoyama T, Shiratsuchi S, Sato A, Mizunoya W, Ikeuchi Y, Furuse M, Allen RE
American journal of physiology. Cell physiology 2010 Mar;298(3):C465-76
American journal of physiology. Cell physiology 2010 Mar;298(3):C465-76
A new model for growth factor activation: type II receptors compete with the prodomain for BMP-7.
Sengle G, Ono RN, Lyons KM, Bächinger HP, Sakai LY
Journal of molecular biology 2008 Sep 12;381(4):1025-39
Journal of molecular biology 2008 Sep 12;381(4):1025-39
Targeting of bone morphogenetic protein growth factor complexes to fibrillin.
Sengle G, Charbonneau NL, Ono RN, Sasaki T, Alvarez J, Keene DR, Bächinger HP, Sakai LY
The Journal of biological chemistry 2008 May 16;283(20):13874-88
The Journal of biological chemistry 2008 May 16;283(20):13874-88
Gene silencing of myostatin in differentiation of chicken embryonic myoblasts by small interfering RNA.
Sato F, Kurokawa M, Yamauchi N, Hattori MA
American journal of physiology. Cell physiology 2006 Sep;291(3):C538-45
American journal of physiology. Cell physiology 2006 Sep;291(3):C538-45
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