MSTN
gene productGDF8
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein negatively regulates skeletal muscle cell proliferation and differentiation. Mutations in this gene are associated with increased skeletal muscle mass in humans and other mammals. [provided by RefSeq, Jul 2016]
Featured antibodies
![]() |
![]() |
0 references | Polyclonal |
IHC
![]() PA ![]() |
![]() |
![]() |
0 references | Monoclonal |
WB
![]() EL ![]() ICC
![]() IHC ![]() FC
![]() |
Antibodies
Filters






