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Protein structure
MSTN
MyostatinGDF8
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein negatively regulates skeletal muscle cell proliferation and differentiation. Mutations in this gene are associated with increased skeletal muscle mass in humans and other mammals. [provided by RefSeq, Jul 2016]
Top validated antibodies |
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| Proteintech Group |  19142-1-AP |
33 references | Polyclonal |
WB
EL
IHC
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| R&D Systems | AF788 |
8 references | Polyclonal |
WB
IHC
BN
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| Novus Biologicals | AF788 |
8 references | Polyclonal |
WB
IHC
BN
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| LSBio | LS-B14976 |
Polyclonal |
WB
EL
IHC
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| antibodies-online | ABIN4313813 |
Monoclonal |
WB
EL
IHC
FC
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