Antibody data
- Antibody Data
- Antigen structure
- References [13]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 55133-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#55133-1-AP, RRID:AB_10793721
- Product name
- S1PR1/EDG1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated S1PR1/EDG1 antibody (Cat. #55133-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IP, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The CAGE-MiR-181b-5p-S1PR1 Axis Regulates Anticancer Drug Resistance and Autophagy in Gastric Cancer Cells.
Interference with the expression of S1PR1 or STAT3 attenuates valvular damage due to rheumatic heart disease.
Inhibition of sphingosine 1-phosphate (S1P) receptor 1/2/3 ameliorates biological dysfunction in rheumatoid arthritis fibroblast-like synoviocyte MH7A cells through Gαi/Gαs rebalancing.
Geniposide downregulates the VEGF/SphK1/S1P pathway and alleviates angiogenesis in rheumatoid arthritis in vivo and in vitro.
Coix Seed Oil Exerts an Anti-Triple-Negative Breast Cancer Effect by Disrupting miR-205/S1PR1 Axis.
Bone marrow mesenchymal stem cells-derived exosomes reduce Aβ deposition and improve cognitive function recovery in mice with Alzheimer's disease by activating sphingosine kinase/sphingosine-1-phosphate signaling pathway.
Combination of sphingosine-1-phosphate receptor 1 (S1PR1) agonist and antiviral drug: a potential therapy against pathogenic influenza virus.
S1P promotes inflammation-induced tube formation by HLECs via the S1PR1/NF-κB pathway.
Hepatocyte-Derived Lipotoxic Extracellular Vesicle Sphingosine 1-Phosphate Induces Macrophage Chemotaxis.
Integrated Metabolomics and Network Pharmacology Approach to Explain Possible Action Mechanisms of Xin-Sheng-Hua Granule for Treating Anemia.
Sphingosine 1-phosphate (S1P) reduces hepatocyte growth factor-induced migration of hepatocellular carcinoma cells via S1P receptor 2.
Sphingosine-1-phosphate mediates AKT/ERK maintenance of dental pulp homoeostasis.
H9N2 avian influenza infection altered expression pattern of sphiogosine-1-phosphate receptor 1 in BALB/c mice.
Yeon M, Kim Y, Pathak D, Kwon E, Kim DY, Jeong MS, Jung HS, Jeoung D
Frontiers in cell and developmental biology 2021;9:666387
Frontiers in cell and developmental biology 2021;9:666387
Interference with the expression of S1PR1 or STAT3 attenuates valvular damage due to rheumatic heart disease.
Xian S, Chen A, Wu Y, Wen H, Lu C, Huang F, Zeng Z
International journal of molecular medicine 2021 Sep;48(3)
International journal of molecular medicine 2021 Sep;48(3)
Inhibition of sphingosine 1-phosphate (S1P) receptor 1/2/3 ameliorates biological dysfunction in rheumatoid arthritis fibroblast-like synoviocyte MH7A cells through Gαi/Gαs rebalancing.
Wang M, Wu H, Wang R, Dai X, Deng R, Wang Y, Bu Y, Sun M, Zhang H
Clinical and experimental pharmacology & physiology 2021 Aug;48(8):1080-1089
Clinical and experimental pharmacology & physiology 2021 Aug;48(8):1080-1089
Geniposide downregulates the VEGF/SphK1/S1P pathway and alleviates angiogenesis in rheumatoid arthritis in vivo and in vitro.
Wang Y, Wu H, Deng R, Dai XJ, Bu YH, Sun MH, Zhang H, Wang MD, Wang RH
Phytotherapy research : PTR 2021 Aug;35(8):4347-4362
Phytotherapy research : PTR 2021 Aug;35(8):4347-4362
Coix Seed Oil Exerts an Anti-Triple-Negative Breast Cancer Effect by Disrupting miR-205/S1PR1 Axis.
Fang T, Jiang YX, Chen L, Huang L, Tian XH, Zhou YD, Nagle DG, Zhang DD
Frontiers in pharmacology 2020;11:529962
Frontiers in pharmacology 2020;11:529962
Bone marrow mesenchymal stem cells-derived exosomes reduce Aβ deposition and improve cognitive function recovery in mice with Alzheimer's disease by activating sphingosine kinase/sphingosine-1-phosphate signaling pathway.
Wang X, Yang G
Cell biology international 2020 Dec 10;
Cell biology international 2020 Dec 10;
Combination of sphingosine-1-phosphate receptor 1 (S1PR1) agonist and antiviral drug: a potential therapy against pathogenic influenza virus.
Zhao J, Zhu M, Jiang H, Shen S, Su X, Shi Y
Scientific reports 2019 Mar 27;9(1):5272
Scientific reports 2019 Mar 27;9(1):5272
S1P promotes inflammation-induced tube formation by HLECs via the S1PR1/NF-κB pathway.
Zheng Z, Zeng YZ, Ren K, Zhu X, Tan Y, Li Y, Li Q, Yi GH
International immunopharmacology 2019 Jan;66:224-235
International immunopharmacology 2019 Jan;66:224-235
Hepatocyte-Derived Lipotoxic Extracellular Vesicle Sphingosine 1-Phosphate Induces Macrophage Chemotaxis.
Liao CY, Song MJ, Gao Y, Mauer AS, Revzin A, Malhi H
Frontiers in immunology 2018;9:2980
Frontiers in immunology 2018;9:2980
Integrated Metabolomics and Network Pharmacology Approach to Explain Possible Action Mechanisms of Xin-Sheng-Hua Granule for Treating Anemia.
Pang HQ, Yue SJ, Tang YP, Chen YY, Tan YJ, Cao YJ, Shi XQ, Zhou GS, Kang A, Huang SL, Shi YJ, Sun J, Tang ZS, Duan JA
Frontiers in pharmacology 2018;9:165
Frontiers in pharmacology 2018;9:165
Sphingosine 1-phosphate (S1P) reduces hepatocyte growth factor-induced migration of hepatocellular carcinoma cells via S1P receptor 2.
Matsushima-Nishiwaki R, Yamada N, Fukuchi K, Kozawa O
PloS one 2018;13(12):e0209050
PloS one 2018;13(12):e0209050
Sphingosine-1-phosphate mediates AKT/ERK maintenance of dental pulp homoeostasis.
Pan HY, Yang H, Shao MY, Xu J, Zhang P, Cheng R, Hu T
International endodontic journal 2015 May;48(5):460-8
International endodontic journal 2015 May;48(5):460-8
H9N2 avian influenza infection altered expression pattern of sphiogosine-1-phosphate receptor 1 in BALB/c mice.
Tong S, Tian J, Wang H, Huang Z, Yu M, Sun L, Liu R, Liao M, Ning Z
Virology journal 2013 Sep 30;10:296
Virology journal 2013 Sep 30;10:296
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Supportive validation
- Submitted by
- Proteintech Group (provider)
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- Experimental details
- The S1PR1 /EDG1 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human S1PR1 /EDG1. This antibody recognizes human, mouse antigen. The S1PR1 /EDG1 antibody has been validated for the following applications: ELISA, WB analysis.