Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- PAB16552 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB16552, RRID:AB_10675476
- Product name
- S1PR1 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of S1PR1.
- Storage
- Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references The sphingosine 1-phosphate receptor 1 causes tissue retention by inhibiting the entry of peripheral tissue T lymphocytes into afferent lymphatics.
S1P1 receptor signaling overrides retention mediated by G alpha i-coupled receptors to promote T cell egress.
Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists.
Ledgerwood LG, Lal G, Zhang N, Garin A, Esses SJ, Ginhoux F, Merad M, Peche H, Lira SA, Ding Y, Yang Y, He X, Schuchman EH, Allende ML, Ochando JC, Bromberg JS
Nature immunology 2008 Jan;9(1):42-53
Nature immunology 2008 Jan;9(1):42-53
S1P1 receptor signaling overrides retention mediated by G alpha i-coupled receptors to promote T cell egress.
Pham TH, Okada T, Matloubian M, Lo CG, Cyster JG
Immunity 2008 Jan;28(1):122-33
Immunity 2008 Jan;28(1):122-33
Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists.
Mandala S, Hajdu R, Bergstrom J, Quackenbush E, Xie J, Milligan J, Thornton R, Shei GJ, Card D, Keohane C, Rosenbach M, Hale J, Lynch CL, Rupprecht K, Parsons W, Rosen H
Science (New York, N.Y.) 2002 Apr 12;296(5566):346-9
Science (New York, N.Y.) 2002 Apr 12;296(5566):346-9
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of S1PR1 in mouse thymus lysate with S1PR1 polyclonal antibody (Cat # PAB16552) at (Lane 1) 1 and (Lane 2) 2 ug/mL .
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Immunohistochemistry of S1PR1 in mouse thymus tissue with S1PR1 polyclonal antibody (Cat # PAB16552) at 5 ug/mL .
- Validation comment
- Immunohistochemistry