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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [7]
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- Validations
- Western blot [1]
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- Product number
- AP05083PU-N - Provider product page
- Provider
- Acris Antibodies GmbH
- Proper citation
- Acris Antibodies GmbH Cat#AP05083PU-N, RRID:AB_1615009
- Product name
- anti EDG-1 / S1PR1
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide derived from the C-terminal of the EDG-1 receptor
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- Lot specific
Submitted references The S1P2 receptor negatively regulates platelet-derived growth factor-induced motility and proliferation.
Sphingosine 1-phosphate activates Weibel-Palade body exocytosis.
Differential transactivation of sphingosine-1-phosphate receptors modulates NGF-induced neurite extension.
Sphingosine-1-phosphate receptor subtype-specific positive and negative regulation of Rac and haematogenous metastasis of melanoma cells.
Transduction of multiple effects of sphingosine 1-phosphate (S1P) on T cell functions by the S1P1 G protein-coupled receptor.
Activation-regulated expression and chemotactic function of sphingosine 1-phosphate receptors in mouse splenic T cells.
Phospholipase D activation by sphingosine 1-phosphate regulates interleukin-8 secretion in human bronchial epithelial cells.
Goparaju SK, Jolly PS, Watterson KR, Bektas M, Alvarez S, Sarkar S, Mel L, Ishii I, Chun J, Milstien S, Spiegel S
Molecular and cellular biology 2005 May;25(10):4237-49
Molecular and cellular biology 2005 May;25(10):4237-49
Sphingosine 1-phosphate activates Weibel-Palade body exocytosis.
Matsushita K, Morrell CN, Lowenstein CJ
Proceedings of the National Academy of Sciences of the United States of America 2004 Aug 3;101(31):11483-7
Proceedings of the National Academy of Sciences of the United States of America 2004 Aug 3;101(31):11483-7
Differential transactivation of sphingosine-1-phosphate receptors modulates NGF-induced neurite extension.
Toman RE, Payne SG, Watterson KR, Maceyka M, Lee NH, Milstien S, Bigbee JW, Spiegel S
The Journal of cell biology 2004 Aug 2;166(3):381-92
The Journal of cell biology 2004 Aug 2;166(3):381-92
Sphingosine-1-phosphate receptor subtype-specific positive and negative regulation of Rac and haematogenous metastasis of melanoma cells.
Yamaguchi H, Kitayama J, Takuwa N, Arikawa K, Inoki I, Takehara K, Nagawa H, Takuwa Y
The Biochemical journal 2003 Sep 15;374(Pt 3):715-22
The Biochemical journal 2003 Sep 15;374(Pt 3):715-22
Transduction of multiple effects of sphingosine 1-phosphate (S1P) on T cell functions by the S1P1 G protein-coupled receptor.
Dorsam G, Graeler MH, Seroogy C, Kong Y, Voice JK, Goetzl EJ
Journal of immunology (Baltimore, Md. : 1950) 2003 Oct 1;171(7):3500-7
Journal of immunology (Baltimore, Md. : 1950) 2003 Oct 1;171(7):3500-7
Activation-regulated expression and chemotactic function of sphingosine 1-phosphate receptors in mouse splenic T cells.
Graeler M, Goetzl EJ
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002 Dec;16(14):1874-8
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002 Dec;16(14):1874-8
Phospholipase D activation by sphingosine 1-phosphate regulates interleukin-8 secretion in human bronchial epithelial cells.
Cummings RJ, Parinandi NL, Zaiman A, Wang L, Usatyuk PV, Garcia JG, Natarajan V
The Journal of biological chemistry 2002 Aug 16;277(33):30227-35
The Journal of biological chemistry 2002 Aug 16;277(33):30227-35
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Supportive validation
- Submitted by
- Acris Antibodies GmbH (provider)
- Main image
- Experimental details
- Western blot analysis of lysates of RH7777 cells transfected with full lenth human EDG-1 protein using anti-EDG-1 CT antibody at 10 µg/ml (1), antibody preincubated with specific blocking peptide (2) and antibody preincubated with non-specific control peptide (3) using Pierce Femto Signal substrate.
