Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
Reference
Comment
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- Product number
- sc-5595 - Provider product page
- Provider
- Santa Cruz Biotechnology
- Proper citation
- Santa Cruz Biotechnology Cat#sc-5595, RRID:AB_2215817
- Product name
- Anti-XPO1
- Antibody type
- Polyclonal
- Antigen
- Recombinant full-length protein
- Reactivity
- Human
- Host
- Rabbit
Submitted references Relevance of gonadotropin-regulated testicular RNA helicase (GRTH/DDX25) in the structural integrity of the chromatoid body during spermatogenesis.
The natural product avrainvillamide binds to the oncoprotein nucleophosmin.
CRM 1-mediated degradation and agonist-induced down-regulation of beta-adrenergic receptor mRNAs.
A Metabolic Enzyme of the Short-Chain Dehydrogenase/Reductase Superfamily May Moonlight in the Nucleus as a Repressor of Promoter Activity
Sato H, Tsai-Morris CH, Dufau ML
Biochimica et biophysica acta 2010 May;1803(5):534-43
Biochimica et biophysica acta 2010 May;1803(5):534-43
The natural product avrainvillamide binds to the oncoprotein nucleophosmin.
Wulff JE, Siegrist R, Myers AG
Journal of the American Chemical Society 2007 Nov 21;129(46):14444-51
Journal of the American Chemical Society 2007 Nov 21;129(46):14444-51
CRM 1-mediated degradation and agonist-induced down-regulation of beta-adrenergic receptor mRNAs.
Bai Y, Lu H, Machida CA
Biochimica et biophysica acta 2006 Oct;1763(10):1076-89
Biochimica et biophysica acta 2006 Oct;1763(10):1076-89
A Metabolic Enzyme of the Short-Chain Dehydrogenase/Reductase Superfamily May Moonlight in the Nucleus as a Repressor of Promoter Activity
Nelli G Markova, Adriana Pinkas-Sarafova, Marcia Simon
Journal of Investigative Dermatology 2006 May;126(9):2019-2031
Journal of Investigative Dermatology 2006 May;126(9):2019-2031
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Supportive validation
- Submitted by
- per
- Main image
- Experimental details
- Western blot analysis of antibody specificity using a routine panel composed of IgG/HSA-depleted human plasma and protein lysates from selected human tissues and cell lines.
- Validation comment
- Band of predicted size in kDa (+/-20%) with additional bands present.
- Primary Ab dilution
- 1:500
- Secondary Ab dilution
- 1:3000
- Lane 1
- Marker [kDa]: 219, 111, 83, 48, 32, 26, 17
- Lane 2
- RT-4
- Lane 3
- U-251MG sp
- Lane 4
- Human Plasma
- Lane 5
- Liver
- Lane 6
- Tonsil
- Theoretical target weight
- [kDa] 123
Supportive validation
- Submitted by
- per
- Main image
- Experimental details
- Immunohistochemical staining of human thyroid gland shows strong nuclear positivity in glandular cells.
- Validation comment
- Staining pattern consistent with experimental and/or bioinformatic data.