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Protein structure
SOCS6
Suppressor of cytokine signaling 6CIS4, Cish4, HSPC060, SOCS4, SSI4, STAI4, STATI4
The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Invitrogen Antibodies |  PA5-50263 |
2 references | Polyclonal |
WB
IHC
OA
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| Proteintech Group | 12425-1-AP |
2 references | Polyclonal |
WB
EL
IHC
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| LSBio | LS-C161383 |
Polyclonal |
WB
IHC
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| Biorbyt | orb186020 |
Polyclonal |
WB
EL
ICC
IHC
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| antibodies-online | ABIN2846977 |
2 references | Polyclonal |
WB
IHC
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