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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [23]
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- Immunohistochemistry [1]
- Other assay [1]
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- Product number
- V3344 - Provider product page
- Provider
- NSJ Bioreagents
- Product name
- TIMP2 Antibody
- Antibody type
- Monoclonal
- Description
- Purified
- Reactivity
- Human, Mouse, Rat, Bovine, Guinea Pig, Rabbit, Zebrafish
- Host
- Mouse
- Conjugate
- Unconjugated
- Antibody clone number
- 3A4
- Vial size
- 20 µg, 100 µg (with BSA, sodium azide), 100 µg (without BSA, sodium azide), 7 ml (prediluted for IHC)
- Concentration
- 0.2 mg/ml
- Storage
- Store the TIMP-2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Submitted references Less is more: low expression of MT1-MMP is optimal to promote migration and tumourigenesis of breast cancer cells.
Interplay Between MMP-9 and TIMP-2 Regulates Ameloblastoma Behavior and Tooth Morphogenesis.
Different Responses in MMP/TIMP Expression of U937 and HepG2 Cells to Dengue Virus Infection.
Expression of metalloproteinases 2 and 9 and tissue inhibitors 1 and 2 as predictors of lymph node metastases in oropharyngeal squamous cell carcinoma.
Tumor progression driven by pathways activating matrix metalloproteinases and their inhibitors.
The Distribution of Matrix Metalloproteinase-2, Tissue Inhibitor of Metalloproteinase-2 and Tissue Inhibitor of Metalloproteinase-4 in Psoriatic Skin
Matrix metalloproteinase-9 and tissue inhibitor of matrix metalloproteinase-2: Prognostic biological markers in invasive prolactinomas.
Metalloproteinase expression is altered in cardiac and skeletal muscle in cancer cachexia.
Stoichiometric expression of MMP-2/TIMP-2 in benign and malignant tumours of the salivary gland.
Epithelial-mesenchymal transition in colorectal cancer tissue of patients with Lynch syndrome.
Oxidative stress and extracellular matrices after hepatectomy and liver transplantation in rats.
Expression of matrix metalloproteinases and their inhibitors in different immunohistochemical-based molecular subtypes of breast cancer.
Feline eosinophilic dermatoses: a retrospective immunohistochemical and ultrastructural study of extracellular matrix remodelling.
Alveolarization genes modulated by fetal tracheal occlusion in the rabbit model for congenital diaphragmatic hernia: a randomized study.
Apoptosis and MMP-2, TIMP-2 expression in cleft lip and palate.
Different strains of Propionibacterium acnes modulate differently the cutaneous innate immunity.
Role of Ca, Fe, Cu and Zn in breast cancer: study by X-ray fluorescence techniques and immunohistochemical analysis
Comparative study of the immunohistochemical expression of tissue inhibitors of metalloproteinases 1 and 2 between clearly invasive carcinomas and "in situ" trophoblast invasion.
Expression of MMP-2, -7, -9, MT1-MMP and TIMP-1 and -2 has no prognostic relevance in patients with advanced epithelial ovarian cancer.
Comparative analysis of the immunohistochemical expression of collagen IV, MMP-9, and TIMP-2 in odontogenic cysts and tumors.
Bovine endometrial metallopeptidases MMP14 and MMP2 and the metallopeptidase inhibitor TIMP2 participate in maternal preparation of pregnancy.
Significant relation of tissue inhibitor of matrix metalloproteinase-2 and its combination with matrix metalloproteinase-2 to survival of patients with cancer of uterine cervix.
The effects of interferon alpha2b on chemically-induced peritoneal fibrosis and on peritoneal tissue MMP-2 and TIMP-2 levels in rats.
Cepeda MA, Pelling JJ, Evered CL, Williams KC, Freedman Z, Stan I, Willson JA, Leong HS, Damjanovski S
Molecular cancer 2016 Oct 18;15(1):65
Molecular cancer 2016 Oct 18;15(1):65
Interplay Between MMP-9 and TIMP-2 Regulates Ameloblastoma Behavior and Tooth Morphogenesis.
Nunia K, Urs AB, Kumar P
Applied immunohistochemistry & molecular morphology : AIMM 2016 May-Jun;24(5):364-72
Applied immunohistochemistry & molecular morphology : AIMM 2016 May-Jun;24(5):364-72
Different Responses in MMP/TIMP Expression of U937 and HepG2 Cells to Dengue Virus Infection.
Seanpong P, Srisaowakarn C, Thammaporn A, Leardkamolkarn V, Kumkate S
Japanese journal of infectious diseases 2015;68(3):221-9
Japanese journal of infectious diseases 2015;68(3):221-9
Expression of metalloproteinases 2 and 9 and tissue inhibitors 1 and 2 as predictors of lymph node metastases in oropharyngeal squamous cell carcinoma.
Burduk PK, Bodnar M, Sawicki P, Szylberg Ł, Wiśniewska E, Kaźmierczak W, Martyńska M, Marszałek A
Head & neck 2015 Mar;37(3):418-22
Head & neck 2015 Mar;37(3):418-22
Tumor progression driven by pathways activating matrix metalloproteinases and their inhibitors.
Bodnar M, Szylberg Ł, Kazmierczak W, Marszalek A
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2015 Jul;44(6):437-43
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2015 Jul;44(6):437-43
The Distribution of Matrix Metalloproteinase-2, Tissue Inhibitor of Metalloproteinase-2 and Tissue Inhibitor of Metalloproteinase-4 in Psoriatic Skin
Sidhom E, Pilmane M, Kisis J
British Journal of Medicine and Medical Research 2015 January;8(10):883-890
British Journal of Medicine and Medical Research 2015 January;8(10):883-890
Matrix metalloproteinase-9 and tissue inhibitor of matrix metalloproteinase-2: Prognostic biological markers in invasive prolactinomas.
Gültekin GD, Çabuk B, Vural Ç, Ceylan S
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2015 Aug;22(8):1282-7
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2015 Aug;22(8):1282-7
Metalloproteinase expression is altered in cardiac and skeletal muscle in cancer cachexia.
Devine RD, Bicer S, Reiser PJ, Velten M, Wold LE
American journal of physiology. Heart and circulatory physiology 2015 Aug 15;309(4):H685-91
American journal of physiology. Heart and circulatory physiology 2015 Aug 15;309(4):H685-91
Stoichiometric expression of MMP-2/TIMP-2 in benign and malignant tumours of the salivary gland.
Kolude B, Adisa AO, Lawal AO, Adeyemi BF, Akinyamoju AO
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015 Apr;36(4):2351-7
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015 Apr;36(4):2351-7
Epithelial-mesenchymal transition in colorectal cancer tissue of patients with Lynch syndrome.
Gu GL, Zhu XQ, Wei XM, Ren L, Li DC, Wang SL
World journal of gastroenterology 2014 Jan 7;20(1):250-7
World journal of gastroenterology 2014 Jan 7;20(1):250-7
Oxidative stress and extracellular matrices after hepatectomy and liver transplantation in rats.
Hori T, Uemoto S, Chen F, Gardner LB, Baine AM, Hata T, Kogure T, Nguyen JH
World journal of hepatology 2014 Feb 27;6(2):72-84
World journal of hepatology 2014 Feb 27;6(2):72-84
Expression of matrix metalloproteinases and their inhibitors in different immunohistochemical-based molecular subtypes of breast cancer.
Kim GE, Lee JS, Choi YD, Lee KH, Lee JH, Nam JH, Choi C, Kim SS, Park MH, Yoon JH, Kweon SS
BMC cancer 2014 Dec 16;14:959
BMC cancer 2014 Dec 16;14:959
Feline eosinophilic dermatoses: a retrospective immunohistochemical and ultrastructural study of extracellular matrix remodelling.
Porcellato I, Giontella A, Mechelli L, Del Rossi E, Brachelente C
Veterinary dermatology 2014 Apr;25(2):86-94, e26
Veterinary dermatology 2014 Apr;25(2):86-94, e26
Alveolarization genes modulated by fetal tracheal occlusion in the rabbit model for congenital diaphragmatic hernia: a randomized study.
Vuckovic A, Herber-Jonat S, Flemmer AW, Roubliova XI, Jani JC
PloS one 2013;8(7):e69210
PloS one 2013;8(7):e69210
Apoptosis and MMP-2, TIMP-2 expression in cleft lip and palate.
Smane L, Pilmane M, Akota I
Stomatologija 2013;15(4):129-34
Stomatologija 2013;15(4):129-34
Different strains of Propionibacterium acnes modulate differently the cutaneous innate immunity.
Jasson F, Nagy I, Knol AC, Zuliani T, Khammari A, Dréno B
Experimental dermatology 2013 Sep;22(9):587-92
Experimental dermatology 2013 Sep;22(9):587-92
Role of Ca, Fe, Cu and Zn in breast cancer: study by X-ray fluorescence techniques and immunohistochemical analysis
Silva M, Silva D, Conceição A, Ribeiro-Silva A, Poletti M
X-Ray Spectrometry 2013 July;42(4):303-311
X-Ray Spectrometry 2013 July;42(4):303-311
Comparative study of the immunohistochemical expression of tissue inhibitors of metalloproteinases 1 and 2 between clearly invasive carcinomas and "in situ" trophoblast invasion.
Dimo B, Ioannidis I, Karameris A, Vilaras G, Tzoumakari P, Nonni A, Patsouris E, Lazaris AC
Medical oncology (Northwood, London, England) 2012 Sep;29(3):2270-5
Medical oncology (Northwood, London, England) 2012 Sep;29(3):2270-5
Expression of MMP-2, -7, -9, MT1-MMP and TIMP-1 and -2 has no prognostic relevance in patients with advanced epithelial ovarian cancer.
Brun JL, Cortez A, Lesieur B, Uzan S, Rouzier R, Daraï E
Oncology reports 2012 Apr;27(4):1049-57
Oncology reports 2012 Apr;27(4):1049-57
Comparative analysis of the immunohistochemical expression of collagen IV, MMP-9, and TIMP-2 in odontogenic cysts and tumors.
Henriques ÁC, Vasconcelos MG, Galvão HC, de Souza LB, de Almeida Freitas R
Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 2011 Oct;112(4):468-75
Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 2011 Oct;112(4):468-75
Bovine endometrial metallopeptidases MMP14 and MMP2 and the metallopeptidase inhibitor TIMP2 participate in maternal preparation of pregnancy.
Ulbrich SE, Meyer SU, Zitta K, Hiendleder S, Sinowatz F, Bauersachs S, Büttner M, Fröhlich T, Arnold GJ, Reichenbach HD, Wolf E, Meyer HH
Molecular and cellular endocrinology 2011 Jan 30;332(1-2):48-57
Molecular and cellular endocrinology 2011 Jan 30;332(1-2):48-57
Significant relation of tissue inhibitor of matrix metalloproteinase-2 and its combination with matrix metalloproteinase-2 to survival of patients with cancer of uterine cervix.
Wang PH, Ko JL, Yang SF, Tsai HT, Tee YT, Han CP, Lin LY, Chen SC, Shih YT
Reproductive sciences (Thousand Oaks, Calif.) 2011 Aug;18(8):798-808
Reproductive sciences (Thousand Oaks, Calif.) 2011 Aug;18(8):798-808
The effects of interferon alpha2b on chemically-induced peritoneal fibrosis and on peritoneal tissue MMP-2 and TIMP-2 levels in rats.
Ucar E, Borazan A, Semerci E, Binici DN, Yaldiz M, Aysal A, Altug E, Kuvandik C, Huzmeli C, Yetim T, Canda S
The Journal of international medical research 2010 Jan-Feb;38(1):187-94
The Journal of international medical research 2010 Jan-Feb;38(1):187-94
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Supportive validation
- Submitted by
- NSJ Bioreagents (provider)
- Main image
- Experimental details
- IHC testing of FFPE human placenta with TIMP-2 antibody (clone 3A4). Required HIER: requires boil tissue sections in 10mM citrate buffer, pH 6, for 10-20 min followed by cooling at RT for 20 min.
Supportive validation
- Submitted by
- NSJ Bioreagents (provider)
- Main image
- Experimental details
- SDS-PAGE Analysis of Purified, BSA-Free TIMP-2 Antibody (clone 3A4). Confirmation of Integrity and Purity of the Antibody.
