TIMP2

gene product
CSC-21K
This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix. [provided by RefSeq, Jul 2008]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

  or   Clear
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Validated within AVI
Eligible for validation within AVI
1110 antibodies from 40 providers.

Antibody properties

General

Applications

or Cancel
AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
99 antibodies
antibodies-online
409 antibodies
NSJ Bioreagents
7 antibodies
Abnova Corporation
22 antibodies
Invitrogen Antibodies
9 antibodies
NovoPro Bioscience Inc.
13 antibodies
Acris Antibodies GmbH
22 antibodies
Biorbyt
50 antibodies
Proteintech Group
1 antibody
OriGene
85 antibodies
Affinity Biosciences
3 antibodies
LifeSpan BioSciences, Inc.
181 antibodies