22779-1-AP

antibody from Proteintech Group

Targeting: LIFR CD118

Provider product page for 22779-1-AP

Western blot

ELISA

Immunocytochemistry

Immunoprecipitation

Immunohistochemistry

Flow cytometry

Antibody data

Antibody Data
Antigen structure
References [16]
Comments [0]
Validations
Western blot [1]
Immunohistochemistry [1]

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Product number: 22779-1-AP - Provider product page
Provider: Proteintech Group
Product name: LIFR antibody
Antibody type: Polyclonal
Description: LIFR antibody (Cat. #22779-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: FC, IF, IHC, IP, WB,ELISA.
Reactivity: Human, Mouse
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

LIFR protein structure - 22779-1-AP shown in red.

Submitted references Pan-cancer analysis identifies LIFR as a prognostic and immunological biomarker for uterine corpus endometrial carcinoma.

Zhang F, Wang Y, Li H, Li L, Yang X, You X, Tang L
Frontiers in oncology 2023;13:1118906

LIFR recruits HGF-producing neutrophils to promote liver injury repair and regeneration.

Deng Y, Zhao Z, Sheldon M, Zhao Y, Teng H, Martinez C, Zhang J, Lin C, Sun Y, Yao F, Zhu H, Ma L
bioRxiv : the preprint server for biology 2023 Mar 21;

OSMR deficiency aggravates pressure overload-induced cardiac hypertrophy by modulating macrophages and OSM/LIFR/STAT3 signalling.

Feng Y, Yuan Y, Xia H, Wang Z, Che Y, Hu Z, Deng J, Li F, Wu Q, Bian Z, Zhou H, Shen D, Tang Q
Journal of translational medicine 2023 Apr 29;21(1):290

Exosomes from human umbilical cord mesenchymal stem cells protect aortas in Db/db mice characterized by combination of metabolomics and proteomics.

Ling MY, Yang XC, Yu N, Song YP, Zheng YJ, Tang CM, Ding WJ, Sun Y, Yan R, Wang SP, Li XH, Gao HQ, Zhang Z, Xing YQ
Archives of biochemistry and biophysics 2022 Nov 30;731:109430

MgFe-LDH Nanoparticles: A Promising Leukemia Inhibitory Factor Replacement for Self-Renewal and Pluripotency Maintenance in Cultured Mouse Embryonic Stem Cells.

He X, Zhu Y, Yang L, Wang Z, Wang Z, Feng J, Wen X, Cheng L, Zhu R
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 May;8(9):2003535

Aptamer-SH2 superbinder-based targeted therapy for pancreatic ductal adenocarcinoma.

Liu AD, Zhou J, Bi XY, Hou GQ, Li SS, Chen Q, Xu H, Cao X
Clinical and translational medicine 2021 Mar;11(3):e337

Exercise plasma boosts memory and dampens brain inflammation via clusterin.

De Miguel Z, Khoury N, Betley MJ, Lehallier B, Willoughby D, Olsson N, Yang AC, Hahn O, Lu N, Vest RT, Bonanno LN, Yerra L, Zhang L, Saw NL, Fairchild JK, Lee D, Zhang H, McAlpine PL, Contrepois K, Shamloo M, Elias JE, Rando TA, Wyss-Coray T
Nature 2021 Dec;600(7889):494-499

A targetable LIFR-NF-κB-LCN2 axis controls liver tumorigenesis and vulnerability to ferroptosis.

Yao F, Deng Y, Zhao Y, Mei Y, Zhang Y, Liu X, Martinez C, Su X, Rosato RR, Teng H, Hang Q, Yap S, Chen D, Wang Y, Chen MM, Zhang M, Liang H, Xie D, Chen X, Zhu H, Chang JC, You MJ, Sun Y, Gan B, Ma L
Nature communications 2021 Dec 17;12(1):7333

Construction and Comprehensive Analysis of a ceRNA Network to Reveal Potential Novel Biomarkers for Triple-Negative Breast Cancer.

Ma L, Song G, Li M, Hao X, Huang Y, Lan J, Yang S, Zhang Z, Zhang G, Mu J
Cancer management and research 2020;12:7061-7075

Detachment of cell sheets from clinically ubiquitous cell culture vessels by ultrasonic vibration.

Imashiro C, Hirano M, Morikura T, Fukuma Y, Ohnuma K, Kurashina Y, Miyata S, Takemura K
Scientific reports 2020 Jun 11;10(1):9468

Enzyme-free release of adhered cells from standard culture dishes using intermittent ultrasonic traveling waves.

Kurashina Y, Imashiro C, Hirano M, Kuribara T, Totani K, Ohnuma K, Friend J, Takemura K
Communications biology 2019;2:393

Formation of Large Scaffold-Free 3-D Aggregates in a Cell Culture Dish by Ultrasound Standing Wave Trapping.

Nakao M, Imashiro C, Kuribara T, Kurashina Y, Totani K, Takemura K
Ultrasound in medicine & biology 2019 May;45(5):1306-1315

Cell Patterning Method on a Clinically Ubiquitous Culture Dish Using Acoustic Pressure Generated From Resonance Vibration of a Disk-Shaped Ultrasonic Transducer.

Imashiro C, Kurashina Y, Kuribara T, Hirano M, Totani K, Takemura K
IEEE transactions on bio-medical engineering 2019 Jan;66(1):111-118

miR-589 promotes gastric cancer aggressiveness by a LIFR-PI3K/AKT-c-Jun regulatory feedback loop.

Zhang F, Li K, Pan M, Li W, Wu J, Li M, Zhao L, Wang H
Journal of experimental & clinical cancer research : CR 2018 Jul 16;37(1):152

Enzyme-free cell detachment mediated by resonance vibration with temperature modulation.

Kurashina Y, Hirano M, Imashiro C, Totani K, Komotori J, Takemura K
Biotechnology and bioengineering 2017 Oct;114(10):2279-2288

Mutations in the leukemia inhibitory factor receptor (LIFR) gene and Lifr deficiency cause urinary tract malformations.

Kosfeld A, Brand F, Weiss AC, Kreuzer M, Goerk M, Martens H, Schubert S, Schäfer AK, Riehmer V, Hennies I, Bräsen JH, Pape L, Amann K, Krogvold L, Bjerre A, Daniel C, Kispert A, Haffner D, Weber RG
Human molecular genetics 2017 May 1;26(9):1716-1731

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: human skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 22779-1-AP(LIFR antibody) at dilution of 1:800
Sample type: tissue

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: The LIFR antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human LIFR. This antibody recognizes human, mouse antigen. The LIFR antibody has been validated for the following applications: ELISA, WB, IHC analysis.
Appendix: 22779-1-AP.pdf

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