Tissue expression
Cell line expression
Protein structure
LIFR
LIF receptor subunit alphaCD118
This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5;8)(p13;q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2018]
Top validated antibodies |
|||||
Proteintech Group | 22779-1-AP | 9 references | Polyclonal |
WB
EL
ICC
IP
IHC
FC |
|
Invitrogen Antibodies | 22779-1-AP | Polyclonal |
WB
ICC
IP
IHC
FC
OA |
||
GeneTex | GTX60183 | 1 references | Polyclonal |
WB
EL
ICC
IP
IHC
FC |
|
NovoPro Bioscience Inc. | 112221 | Polyclonal |
WB
EL
IP
IHC
FC
|
||
LSBio | LS-C670584 | Polyclonal |
WB
EL
ICC
IHC |
All Antibodies
Filters
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider