MA1-81739

antibody from Invitrogen Antibodies

Targeting: IGF1R CD221, IGFIR, IGFR, JTK13, MGC18216

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Other assay (Recommended by provider)

Antibody Data

Product number

MA1-81739

Provider

Invitrogen Antibodies

Product name

IGF1R alpha Monoclonal Antibody (1H7)

Antibody type

Monoclonal

Antigen

Other

Description

Clone 1H7 recognizes an epitope in the alpha subunits of CD221, demonstrated by Western blotting, and is reported to partically block binding of IGF-I and IGF-II to CD221. This product requires protein digestion pre-treatment of paraffin sections using trypsin or pronase. A suggested positive control for immunohistochemical applications is pancreas or placenta. For FACS analysis, use 10 µL of the suggested working dilution to label 1x10^6 cells in 100 µL. This product is a low-endotoxin, preservative-free formulation. Endotoxin level is

Reactivity

Human

Host

Mouse

Isotype

IgG

Antibody clone number

1H7

Vial size

500 µg

Concentration

1 mg/mL

Storage

-20° C, Avoid Freeze/Thaw Cycles

References

Submitted references

Differential activation of a C/EBP beta isoform by a novel redox switch may confer the lipopolysaccharide-inducible expression of interleukin-6 gene.

Su WC, Chou HY, Chang CJ, Lee YM, Chen WH, Huang KH, Lee MY, Lee SC
The Journal of biological chemistry 2003 Dec 19;278(51):51150-8