IGF1R

gene product
CD221, IGFIR, IGFR, JTK13, MGC18216
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
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AntibodyRefsTypeWBELICCIPIHCFC
R&D Systems
8 antibodies
Novus Biologicals
62 antibodies
antibodies-online
691 antibodies
Invitrogen Antibodies
38 antibodies
Biorbyt
111 antibodies