IGF1R

gene product
CD221, IGFIR, IGFR, JTK13, MGC18216
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antibody

  or   Clear
Enhanced validation
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Validated within AVI
Eligible for validation within AVI
2558 antibodies from 48 providers.

Antibody properties

General

Applications

or Cancel
Antibody
R&D Systems
16 antibodies
Proteintech Group
2 antibodies
Novus Biologicals
97 antibodies
antibodies-online
691 antibodies
OriGene
56 antibodies
Biorbyt
111 antibodies
GeneTex
21 antibodies
Abgent
11 antibodies
NSJ Bioreagents
4 antibodies
Invitrogen Antibodies
46 antibodies
Affinity Biosciences
13 antibodies
Cell Signaling Technology, Inc
12 antibodies
Abnova Corporation
23 antibodies
LifeSpan BioSciences, Inc.
457 antibodies
Arigo
7 antibodies
Boster Biological Technology
9 antibodies
Signalway Antibody LLC
8 antibodies
Cusabio Biotech Co., Ltd
22 antibodies
Acris Antibodies GmbH
40 antibodies
Enzo Life Sciences
28 antibodies
NovoPro Bioscience Inc.
14 antibodies
Wuhan Fine Biotech Co., Ltd.
1 antibody
Aviva Systems Biology
20 antibodies
Santa Cruz Biotechnology
1 antibody
ProSci
14 antibodies
St John's Laboratory
21 antibodies
BioLegend
6 antibodies
Bioworld Technology, Inc
8 antibodies
Creative Biolabs
320 antibodies
Abbkine Scientific Co.Ltd.
9 antibodies
HUABIO Research
1 antibody
MyBioSource
24 antibodies
RabMAbs
2 antibodies
United States Biological
163 antibodies
Abbexa
29 antibodies
Creative Diagnostics
20 antibodies
MilliporeSigma / Merck KGaA
10 antibodies
Atlas Antibodies
1 antibody
Miltenyi Biotec
6 antibodies
GenWay
12 antibodies
RayBiotech, Inc.
4 antibodies
Sino Biological Inc.
7 antibodies
Leading Biology
9 antibodies
EMD Millipore
9 antibodies
Absolute Antibody
42 antibodies
Abbiotec
3 antibodies
eBioscience, An Affymetrix Company
6 antibodies