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- Antigen structure
- References [10]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- NB110-87052 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB110-87052, RRID:AB_1199337
- Product name
- Mouse Monoclonal IGF-I R/IGF1R Antibody
- Antibody type
- Monoclonal
- Description
- Unpurified.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references IGF and mTOR pathway expression and in vitro effects of linsitinib and mTOR inhibitors in adrenocortical cancer.
Two prostate cancer‑associated polymorphisms in the 3'UTR of IGF1R influences prostate cancer susceptibility by affecting miRNA binding.
Germ-line variants identified by next generation sequencing in a panel of estrogen and cancer associated genes correlate with poor clinical outcome in Lynch syndrome patients.
Tau and PTEN status as predictive markers for response to trastuzumab and paclitaxel in patients with HER2-positive breast cancer.
Upregulation of Claudin-4, CAIX and GLUT-1 in distant breast cancer metastases.
Differential expression of growth factor receptors and membrane-bound tumor markers for imaging in male and female breast cancer.
Analysis of expression of membrane-bound tumor markers in ductal carcinoma in situ of the breast: paving the way for molecular imaging.
Circulating insulin-like growth factors may contribute substantially to insulin receptor isoform A and insulin receptor isoform B signalling.
Immunophenotyping invasive breast cancer: paving the road for molecular imaging.
MicroRNA-375 inhibits tumour growth and metastasis in oesophageal squamous cell carcinoma through repressing insulin-like growth factor 1 receptor.
De Martino MC, van Koetsveld PM, Feelders RA, de Herder WW, Dogan F, Janssen JAMJL, Hofste Op Bruinink D, Pivonello C, Waaijers AM, Colao A, de Krijger RR, Pivonello R, Hofland LJ
Endocrine 2019 Jun;64(3):673-684
Endocrine 2019 Jun;64(3):673-684
Two prostate cancer‑associated polymorphisms in the 3'UTR of IGF1R influences prostate cancer susceptibility by affecting miRNA binding.
Wang H, Huang W, Yu X, Li W, Huang Y, Mo Z, Gao Y, Zhou Q, Hu Y
Oncology reports 2019 Jan;41(1):512-524
Oncology reports 2019 Jan;41(1):512-524
Germ-line variants identified by next generation sequencing in a panel of estrogen and cancer associated genes correlate with poor clinical outcome in Lynch syndrome patients.
Jóri B, Kamps R, Xanthoulea S, Delvoux B, Blok MJ, Van de Vijver KK, de Koning B, Oei FT, Tops CM, Speel EJ, Kruitwagen RF, Gomez-Garcia EB, Romano A
Oncotarget 2015 Dec 1;6(38):41108-22
Oncotarget 2015 Dec 1;6(38):41108-22
Tau and PTEN status as predictive markers for response to trastuzumab and paclitaxel in patients with HER2-positive breast cancer.
Koo DH, Lee HJ, Ahn JH, Yoon DH, Kim SB, Gong G, Son BH, Ahn SH, Jung KH
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015 Aug;36(8):5865-71
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015 Aug;36(8):5865-71
Upregulation of Claudin-4, CAIX and GLUT-1 in distant breast cancer metastases.
Jiwa LS, van Diest PJ, Hoefnagel LD, Wesseling J, Wesseling P, Dutch Distant Breast Cancer Metastases Consortium, Moelans CB
BMC cancer 2014 Nov 22;14:864
BMC cancer 2014 Nov 22;14:864
Differential expression of growth factor receptors and membrane-bound tumor markers for imaging in male and female breast cancer.
Vermeulen JF, Kornegoor R, van der Wall E, van der Groep P, van Diest PJ
PloS one 2013;8(1):e53353
PloS one 2013;8(1):e53353
Analysis of expression of membrane-bound tumor markers in ductal carcinoma in situ of the breast: paving the way for molecular imaging.
Vermeulen JF, van der Wall E, Witkamp AJ, van Diest PJ
Cellular oncology (Dordrecht) 2013 Jul;36(4):333-40
Cellular oncology (Dordrecht) 2013 Jul;36(4):333-40
Circulating insulin-like growth factors may contribute substantially to insulin receptor isoform A and insulin receptor isoform B signalling.
Varewijck AJ, Brugts MP, Frystyk J, Goudzwaard JA, Uitterlinden P, Waaijers AM, Feng Y, Dimitrov DS, Lamberts SW, Hofland LJ, Janssen JA
Molecular and cellular endocrinology 2013 Jan 5;365(1):17-24
Molecular and cellular endocrinology 2013 Jan 5;365(1):17-24
Immunophenotyping invasive breast cancer: paving the road for molecular imaging.
Vermeulen JF, van Brussel AS, van der Groep P, Morsink FH, Bult P, van der Wall E, van Diest PJ
BMC cancer 2012 Jun 13;12:240
BMC cancer 2012 Jun 13;12:240
MicroRNA-375 inhibits tumour growth and metastasis in oesophageal squamous cell carcinoma through repressing insulin-like growth factor 1 receptor.
Kong KL, Kwong DL, Chan TH, Law SY, Chen L, Li Y, Qin YR, Guan XY
Gut 2012 Jan;61(1):33-42
Gut 2012 Jan;61(1):33-42
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: IGF-I R Antibody (3G5C1) [NB110-87052] - Analysis using IGF1R-Beta mouse mAb against truncated IGF1R recombinant protein.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: IGF-I R Antibody (3G5C1) [NB110-87052] - Analysis of ovarian cancer tissues using IGF1R-Beta mouse mAb with DAB staining.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: IGF-I R Antibody (3G5C1) [NB110-87052] - Analysis of rectum cancer tissues using IGF1R-Beta mouse mAb with DAB staining.
