ABIN1355850

antibody from antibodies-online

Targeting: IGF1R CD221, IGFIR, IGFR, JTK13, MGC18216

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN1355850

Provider

antibodies-online

Product name

anti-Insulin-Like Growth Factor I Receptor (IGF1R) (pTyr1161) antibody

Antibody type

Polyclonal

Antigen

Peptide sequence around phosphorylation site of pTyr1161 (D-I-Y (p) -E-T) derived from Human IGF-1R. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

pTyr1161

Vial size

100 μL

Concentration

1 mg/mL

Storage

Store at -20°C

References

Submitted references

Small-molecule inhibition and activation-loop trans-phosphorylation of the IGF1 receptor.

Wu J, Li W, Craddock BP, Foreman KW, Mulvihill MJ, Ji QS, Miller WT, Hubbard SR
The EMBO journal 2008 Jul 23;27(14):1985-94

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Hybrid receptors formed by insulin receptor (IR) and insulin-like growth factor I receptor (IGF-IR) have low insulin and high IGF-1 affinity irrespective of the IR splice variant.

Slaaby R, Schäffer L, Lautrup-Larsen I, Andersen AS, Shaw AC, Mathiasen IS, Brandt J
The Journal of biological chemistry 2006 Sep 8;281(36):25869-74

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Characterization of human placental insulin-like growth factor-I/insulin hybrid receptors by protein microsequencing and purification.

Kasuya J, Paz IB, Maddux BA, Goldfine ID, Hefta SA, Fujita-Yamaguchi Y
Biochemistry 1993 Dec 14;32(49):13531-6