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- Antibody Data
- Antigen structure
- References [111]
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- Western blot [1]
- Immunocytochemistry [1]
- Immunoprecipitation [1]
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- Product number
- 17519-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17519-1-AP, RRID:AB_10642833
- Product name
- RIPK1-Specific antibody
- Antibody type
- Polyclonal
- Description
- RIPK1-Specific antibody (Cat. #17519-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Novel small molecule DMAMCL induces differentiation in rhabdomyosarcoma by downregulating of DLL1.
Naringenin reduces oxidative stress and necroptosis, apoptosis, and pyroptosis in random-pattern skin flaps by enhancing autophagy.
Alleviation of temporomandibular joint osteoarthritis by targeting RIPK1-mediated inflammatory signalling.
Targeting P2Y(14)R protects against necroptosis of intestinal epithelial cells through PKA/CREB/RIPK1 axis in ulcerative colitis.
Effect of lipopolysaccharide on TAK1-mediated hepatocyte PANoptosis through Toll-like receptor 4 during acute liver failure.
Electroacupuncture Inhibits Neuroinflammation Induced by Astrocytic Necroptosis Through RIP1/MLKL/TLR4 Pathway in a Mouse Model of Spinal Cord Injury.
PTGER3 knockdown inhibits the vulnerability of triple-negative breast cancer to ferroptosis.
The cGAS/STING signaling pathway is involved in sevoflurane induced neuronal necroptosis via regulating microglia M1 polarization.
An investigation of the distributions of ferroptosis and necroptosis mediators in the maternal-fetal interface at different days of rat pregnancy.
RIP1/3-dependent programmed necrosis induces intestinal injury in septic rats.
SREBP1 deficiency diminishes glutamate-mediated HT22 cell damage and hippocampal neuronal pyroptosis induced by status epilepticus.
Inhibition of RIPK1 alleviating vascular smooth muscle cells osteogenic transdifferentiation via Runx2.
TRAF2 inhibits senescence in hepatocellular carcinoma cells via regulating the ROMO1/ NAD(+)/SIRT3/SOD2 axis.
Pimpinellin ameliorates macrophage inflammation by promoting RNF146-mediated PARP1 ubiquitination.
3-Monochloropropane-1,2-diol esters induce HepG2 cells necroptosis via CTSB/TFAM/ROS pathway.
Nanointegrative Glycoengineering-Activated Necroptosis of Triple Negative Breast Cancer Stem Cells Enables Self-Amplifiable Immunotherapy for Systemic Tumor Rejection.
OSW-1 triggers necroptosis in colorectal cancer cells through the RIPK1/RIPK3/MLKL signaling pathway facilitated by the RIPK1-p62/SQSTM1 complex.
Evaluation of 6-PPD quinone toxicity on lung of male BALB/c mice by quantitative proteomics.
Polystyrene nanoplastics and cadmium co-exposure aggravated cardiomyocyte damage in mice by regulating PANoptosis pathway.
N-acetyl-L-cysteine alleviated the oxidative stress-induced inflammation and necroptosis caused by excessive NiCl(2) in primary spleen lymphocytes.
ZY-444 inhibits the growth and metastasis of prostate cancer by targeting TNFAIP3 through TNF signaling pathway.
Brazilin inhibits bladder cancer by promoting cell necroptosis.
Activation of the TNF-α-Necroptosis Pathway in Parvalbumin-Expressing Interneurons of the Anterior Cingulate Cortex Contributes to Neuropathic Pain.
Intranasal inoculation of female BALB/c mice with replication-deficient human adenovirus type 5 expressing SARS-CoV-2 nucleocapsid protein aggravates lung pathology upon re-encountering the antigen.
Polystyrene microplastics with different sizes induce the apoptosis and necroptosis in liver through the PTEN/PI3K/AKT/autophagy axis.
Deletion of Bak1 alleviates microglial necroptosis and neuroinflammation after experimental subarachnoid hemorrhage.
Necroptosis signaling and mitochondrial dysfunction cross-talking facilitate cell death mediated by chelerythrine in glioma.
DBP induced autophagy and necrotic apoptosis in HepG2 cells via the mitochondrial damage pathway.
Polysaccharide from Strongylocentrotus nudus eggs regulates intestinal epithelial autophagy through CD36/PI3K-Akt pathway to ameliorate inflammatory bowel disease.
Inhibition of GSK3β activity alleviates acute liver failure via suppressing multiple programmed cell death.
Caspofungin Suppresses Brain Cell Necroptosis in Ischemic Stroke Rats via Up-Regulation of Pellino3.
Functional Characterization of a Familial ALS-Associated Missense TBK1 (p-Arg573Gly) Mutation in Patient-Derived Lymphoblasts.
N-acetylcysteine combined with insulin attenuates myocardial injury in canines with type 1 diabetes mellitus by modulating TNF-α-mediated apoptotic pathways and affecting linear ubiquitination.
Serinc2 deficiency exacerbates sepsis-induced cardiomyopathy by enhancing necroptosis and apoptosis.
Alcohol induces hepatocytes necroptosis through the LC3/RIPK1/RIPK3 pathway.
Baicalin suppressed necroptosis and inflammation against chlorpyrifos toxicity; involving in ER stress and oxidative stress in carp gills.
[Dihydromyricetin alleviates pyroptosis and necroptosis in mice with MPTP-induced chronic Parkinson's disease by inducing autophagy].
LncRNA NR_003508 Suppresses Mycobacterium tuberculosis-Induced Programmed Necrosis via Sponging miR-346-3p to Regulate RIPK1.
Role of SESTRIN2/AMPK/ULK1 pathway activation and lysosomes dysfunction in NaAsO(2)-induced liver injury under oxidative stress.
Necrosulfonamide Alleviates Acute Brain Injury of Intracerebral Hemorrhage via Inhibiting Inflammation and Necroptosis.
A novel necroptosis-related gene index for predicting prognosis and a cold tumor immune microenvironment in stomach adenocarcinoma.
Paeoniflorin directly binds to TNFR1 to regulate podocyte necroptosis in diabetic kidney disease.
Protective effect of inhibiting necroptosis on gentamicin-induced nephrotoxicity.
Novel pharmacological inhibition of JMJD3 improves necrotizing enterocolitis by attenuating the inflammatory response and ameliorating intestinal injury.
Study of the synergistic effect of singlet oxygen with other plasma-generated ROS in fungi inactivation during water disinfection.
Tea polyphenols alleviates acetochlor-induced apoptosis and necroptosis via ROS/MAPK/NF-κB signaling in Ctenopharyngodon idellus kidney cells.
Myo-inositol oxygenase overexpression exacerbates cadmium-induced kidney injury via oxidant stress and necroptosis.
Selenium Deficiency Induces Apoptosis and Necroptosis Through ROS/MAPK Signal in Human Uterine Smooth Muscle Cells.
The protective effect of rabeprazole on cisplatin-induced apoptosis and necroptosis of renal proximal tubular cells.
Proteomic Mapping and Targeting of Mitotic Pericentriolar Material in Tumors Bearing Centrosome Amplification.
Combination of Compound Kushen Injection and cisplatin shows synergistic antitumor activity in p53-R273H/P309S mutant colorectal cancer cells through inducing apoptosis.
The role of KIAA1191 in the necroptotic pathway of multiple myeloma.
Salmonella pSLT-encoded effector SpvB promotes RIPK3-dependent necroptosis in intestinal epithelial cells.
Therapeutic effects of JLX001 on neuronal necroptosis after cerebral ischemia-reperfusion in rats.
Targeting Cell Membranes, Depleting ROS by Dithiane and Thioketal-Containing Polymers with Pendant Cholesterols Delivering Necrostatin-1 for Glaucoma Treatment.
Developmental exposure to chlorpyrifos causes neuroinflammation via necroptosis in mouse hippocampus and human microglial cell line.
Biotransformation of graphene oxide within lung fluids could intensify its synergistic biotoxicity effect with cadmium by inhibiting cellular efflux of cadmium.
LncRNA HABON promoted liver cancer cells survival under hypoxia by inhibiting mPTP opening.
Autophagy-Related LC3 Accumulation Interacted Directly With LIR Containing RIPK1 and RIPK3, Stimulating Necroptosis in Hypoxic Cardiomyocytes.
Astragalin Protects against Spinal Cord Ischemia Reperfusion Injury through Attenuating Oxidative Stress-Induced Necroptosis.
Yi-Qi-Jian-Pi Formula Suppresses RIPK1/RIPK3-Complex-Dependent Necroptosis of Hepatocytes Through ROS Signaling and Attenuates Liver Injury in Vivo and in Vitro.
Pterostilbene attenuates RIPK3-dependent hepatocyte necroptosis in alcoholic liver disease via SIRT2-mediated NFATc4 deacetylation.
Protective action of ultrasound-guided intraparenchymal transplantation of BMSCs in adriamycin nephropathy rats through the RIPK3/MLKL and NLRP3 pathways.
Ultrasound-Guided Transplantation of Mesenchymal Stem Cells Improves Adriamycin Nephropathy in Rats Through the RIPK3/MLKL and TLR-4/NF-κB Signaling.
Pterocephin A, a novel Triterpenoid Saponin from Pterocephalus hookeri induced liver injury by activation of necroptosis.
Methamphetamine exposure induces neuronal programmed necrosis by activating the receptor-interacting protein kinase 3 -related signalling pathway.
Lansoprazole promotes cisplatin-induced acute kidney injury via enhancing tubular necroptosis.
Utilizing an Animal Model to Identify Brain Neurodegeneration-Related Biomarkers in Aging.
Deficiency of NEAT1 prevented MPP(+)-induced inflammatory response, oxidative stress and apoptosis in dopaminergic SK-N-SH neuroblastoma cells via miR-1277-5p/ARHGAP26 axis.
The Performance of HepG2 and HepaRG Systems through the Glass of Acetaminophen-Induced Toxicity.
Traditional herbal formula Wu-Mei-Wan alleviates TNBS-induced colitis in mice by inhibiting necroptosis through increasing RIPK3 O-GlcNAcylation.
Cadmium exposure induces TNF-α-mediated necroptosis via FPR2/TGF-β/NF-κB pathway in swine myocardium.
The Herbal Medicine Scutellaria-Coptis Alleviates Intestinal Mucosal Barrier Damage in Diabetic Rats by Inhibiting Inflammation and Modulating the Gut Microbiota.
Jia-Ji Electro-Acupuncture Improves Locomotor Function With Spinal Cord Injury by Regulation of Autophagy Flux and Inhibition of Necroptosis.
M10, a Myricetin-3-O-b-D-Lactose Sodium Salt, Prevents Ulcerative Colitis Through Inhibiting Necroptosis in Mice.
Combination of Rapamycin and MK-2206 Induced Cell Death via Autophagy and Necroptosis in MYCN-Amplified Neuroblastoma Cell Lines.
Protective effect of astaxanthin against SnS(2) nanoflowers induced testes toxicity by suppressing RIPK1-RIPK3-MLKL signaling in mice.
Acetylharpagide Protects Mice from Staphylococcus Aureus-Induced Acute Lung Injury by Inhibiting NF-κB Signaling Pathway.
Necroptosis mediated by impaired autophagy flux contributes to adverse ventricular remodeling after myocardial infarction.
A new perspective of triptolide-associated hepatotoxicity: the relevance of NF- κ B and NF- κ B-mediated cellular FLICE-inhibitory protein.
New insights in acetaminophen toxicity: HMGB1 contributes by itself to amplify hepatocyte necrosis in vitro through the TLR4-TRIF-RIPK3 axis.
Insights into mechanisms of pranoprofen-induced apoptosis and necroptosis in human corneal stromal cells.
Raman micro-spectroscopy monitoring of cytochrome c redox state in Candida utilis during cell death under low-temperature plasma-induced oxidative stress.
SETDB1-Mediated Cell Fate Transition between 2C-Like and Pluripotent States.
Chidamide induces necroptosis via regulation of c‑FLIPL expression in Jurkat and HUT‑78 cells.
Norfloxacin induces apoptosis and necroptosis in human corneal epithelial cells.
ZYZ-803 Mitigates Endoplasmic Reticulum Stress-Related Necroptosis after Acute Myocardial Infarction through Downregulating the RIP3-CaMKII Signaling Pathway.
The role of the LncRNA-FA2H-2-MLKL pathway in atherosclerosis by regulation of autophagy flux and inflammation through mTOR-dependent signaling.
Necrostatin-1 Attenuates Renal Ischemia and Reperfusion Injury via Meditation of HIF-1α/mir-26a/TRPC6/PARP1 Signaling.
High glucose-induced apoptosis and necroptosis in podocytes is regulated by UCHL1 via RIPK1/RIPK3 pathway.
Quetiapine induces myocardial necroptotic cell death through bidirectional regulation of cannabinoid receptors.
Evaluation of the Liver Toxicity of Pterocephalus hookeri Extract via Triggering Necrosis.
Gallic acid protects against ethanol-induced hepatocyte necroptosis via an NRF2-dependent mechanism.
Dexmedetomidine Preconditioning Protects Cardiomyocytes Against Hypoxia/Reoxygenation-Induced Necroptosis by Inhibiting HMGB1-Mediated Inflammation.
A new perspective of triptolide-associated hepatotoxicity: Liver hypersensitivity upon LPS stimulation.
The Interrelationship of Pharmacologic Ascorbate Induced Cell Death and Ferroptosis.
Neferine, a Bisbenzylisoquinoline Alkaloid, Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis.
Necrostatin-1 promotes ectopic periodontal tissue like structure regeneration in LPS-treated PDLSCs.
Curcumol induces RIPK1/RIPK3 complex-dependent necroptosis via JNK1/2-ROS signaling in hepatic stellate cells.
Trail armed oncolytic poxvirus suppresses lung cancer cell by inducing apoptosis.
Airn Regulates Igf2bp2 Translation in Cardiomyocytes.
Receptor-Interacting Protein 3/Caspase-8 May Regulate Inflammatory Response and Promote Tissue Regeneration in the Periodontal Microenvironment.
MicroRNA-326 sensitizes human glioblastoma cells to curcumin via the SHH/GLI1 signaling pathway.
Dihydrotanshinone I, a natural product, ameliorates DSS-induced experimental ulcerative colitis in mice.
Regulation of RIPK1 activation by TAK1-mediated phosphorylation dictates apoptosis and necroptosis.
The Machado-Joseph Disease Deubiquitinase Ataxin-3 Regulates the Stability and Apoptotic Function of p53.
The ORF3 Protein of Genotype 1 Hepatitis E Virus Suppresses TLR3-induced NF-κB Signaling via TRADD and RIP1.
Gelatin promotes murine fibrosarcoma L929 cell detachment and protects the cells from TNFα-induced cytotoxicity.
Nicotine Induced Murine Spermatozoa Apoptosis via Up-Regulation of Deubiquitinated RIP1 by Trim27 Promoter Hypomethylation.
Nrf2 Knockdown Disrupts the Protective Effect of Curcumin on Alcohol-Induced Hepatocyte Necroptosis.
Type I collagen gel protects murine fibrosarcoma L929 cells from TNFα-induced cell death.
Li Q, Chen Y, Chen Y, Hua Z, Gong B, Liu Z, Thiele CJ, Li Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116562
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116562
Naringenin reduces oxidative stress and necroptosis, apoptosis, and pyroptosis in random-pattern skin flaps by enhancing autophagy.
Jiang S, Ma F, Lou J, Li J, Shang X, Li Y, Wu J, Xu S
European journal of pharmacology 2024 May 5;970:176455
European journal of pharmacology 2024 May 5;970:176455
Alleviation of temporomandibular joint osteoarthritis by targeting RIPK1-mediated inflammatory signalling.
Cao X, Peng S, Yan Y, Li J, Zhou J, Dai H, Xu J
Journal of cellular and molecular medicine 2024 Mar;28(5):e17929
Journal of cellular and molecular medicine 2024 Mar;28(5):e17929
Targeting P2Y(14)R protects against necroptosis of intestinal epithelial cells through PKA/CREB/RIPK1 axis in ulcerative colitis.
Liu C, Wang H, Han L, Zhu Y, Ni S, Zhi J, Yang X, Zhi J, Sheng T, Li H, Hu Q
Nature communications 2024 Mar 7;15(1):2083
Nature communications 2024 Mar 7;15(1):2083
Effect of lipopolysaccharide on TAK1-mediated hepatocyte PANoptosis through Toll-like receptor 4 during acute liver failure.
Li W, Zhang W, Zhang D, Shi C, Wang Y
International immunopharmacology 2024 Mar 10;129:111612
International immunopharmacology 2024 Mar 10;129:111612
Electroacupuncture Inhibits Neuroinflammation Induced by Astrocytic Necroptosis Through RIP1/MLKL/TLR4 Pathway in a Mouse Model of Spinal Cord Injury.
Zhao H, Zong X, Li L, Li N, Liu C, Zhang W, Li J, Yang C, Huang S
Molecular neurobiology 2024 Jun;61(6):3258-3271
Molecular neurobiology 2024 Jun;61(6):3258-3271
PTGER3 knockdown inhibits the vulnerability of triple-negative breast cancer to ferroptosis.
Wang S, Zhang Y, Zhang D, Meng J, Che N, Zhao X, Liu T
Cancer science 2024 Jun;115(6):2067-2081
Cancer science 2024 Jun;115(6):2067-2081
The cGAS/STING signaling pathway is involved in sevoflurane induced neuronal necroptosis via regulating microglia M1 polarization.
Zhang Q, Li Y, Liu Y, Wang X, Yang Y, Shi L
Cellular signalling 2024 Jul;119:111195
Cellular signalling 2024 Jul;119:111195
An investigation of the distributions of ferroptosis and necroptosis mediators in the maternal-fetal interface at different days of rat pregnancy.
Tatar M, Tüfekci KK
Anatomia, histologia, embryologia 2024 Jan;53(1):e12991
Anatomia, histologia, embryologia 2024 Jan;53(1):e12991
RIP1/3-dependent programmed necrosis induces intestinal injury in septic rats.
Ye S, Qi X, Liu Y, Zhuang L, Gu Z
Acta biochimica et biophysica Sinica 2024 Jan 25;56(1):106-113
Acta biochimica et biophysica Sinica 2024 Jan 25;56(1):106-113
SREBP1 deficiency diminishes glutamate-mediated HT22 cell damage and hippocampal neuronal pyroptosis induced by status epilepticus.
Ye X, Lin JY, Chen LX, Wu XC, Ma KJ, Li BX, Fang YX
Heliyon 2024 Jan 15;10(1):e23945
Heliyon 2024 Jan 15;10(1):e23945
Inhibition of RIPK1 alleviating vascular smooth muscle cells osteogenic transdifferentiation via Runx2.
Li Y, Jie W, Qi Y, Mo M, Lian Y, Yin L, Huang H
iScience 2024 Feb 16;27(2):108766
iScience 2024 Feb 16;27(2):108766
TRAF2 inhibits senescence in hepatocellular carcinoma cells via regulating the ROMO1/ NAD(+)/SIRT3/SOD2 axis.
Yao J, Liang X, Xu S, Liu Y, Shui L, Li S, Guo H, Xiao Z, Zhao Y, Zheng M
Free radical biology & medicine 2024 Feb 1;211:47-62
Free radical biology & medicine 2024 Feb 1;211:47-62
Pimpinellin ameliorates macrophage inflammation by promoting RNF146-mediated PARP1 ubiquitination.
Yang L, Du M, Liu K, Wang P, Zhu J, Li F, Wang Z, Huang K, Liang M
Phytotherapy research : PTR 2024 Apr;38(4):1783-1798
Phytotherapy research : PTR 2024 Apr;38(4):1783-1798
3-Monochloropropane-1,2-diol esters induce HepG2 cells necroptosis via CTSB/TFAM/ROS pathway.
Guan S, Qu X, Wang J, Zhang D, Lu J
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Apr;186:114525
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Apr;186:114525
Nanointegrative Glycoengineering-Activated Necroptosis of Triple Negative Breast Cancer Stem Cells Enables Self-Amplifiable Immunotherapy for Systemic Tumor Rejection.
Zhao Y, Li Y, He J, Li M, Yao X, Yang H, Luo Z, Luo P, Su M
Advanced healthcare materials 2024 Apr;13(9):e2303337
Advanced healthcare materials 2024 Apr;13(9):e2303337
OSW-1 triggers necroptosis in colorectal cancer cells through the RIPK1/RIPK3/MLKL signaling pathway facilitated by the RIPK1-p62/SQSTM1 complex.
Wang N, Li CY, Yao TF, Kang XD, Guo HS
World journal of gastroenterology 2024 Apr 21;30(15):2155-2174
World journal of gastroenterology 2024 Apr 21;30(15):2155-2174
Evaluation of 6-PPD quinone toxicity on lung of male BALB/c mice by quantitative proteomics.
He W, Chao J, Gu A, Wang D
The Science of the total environment 2024 Apr 20;922:171220
The Science of the total environment 2024 Apr 20;922:171220
Polystyrene nanoplastics and cadmium co-exposure aggravated cardiomyocyte damage in mice by regulating PANoptosis pathway.
Ye J, Qiu W, Pang X, Su Y, Zhang X, Huang J, Xie H, Liao J, Tang Z, Chen Z, Li F, Xiong Z, Su R
Environmental pollution (Barking, Essex : 1987) 2024 Apr 15;347:123713
Environmental pollution (Barking, Essex : 1987) 2024 Apr 15;347:123713
N-acetyl-L-cysteine alleviated the oxidative stress-induced inflammation and necroptosis caused by excessive NiCl(2) in primary spleen lymphocytes.
Zhang X, Xu L, Ma W, Shi B, Liu Q, Song Y, Fang C, Liu P, Qiao S, Cai J, Zhang Z
Frontiers in immunology 2023;14:1146645
Frontiers in immunology 2023;14:1146645
ZY-444 inhibits the growth and metastasis of prostate cancer by targeting TNFAIP3 through TNF signaling pathway.
Han MT, Pei H, Sun QQ, Wang CL, Li P, Xie YY, Cao LJ, Zhang XX, Sun ZL
American journal of cancer research 2023;13(4):1533-1546
American journal of cancer research 2023;13(4):1533-1546
Brazilin inhibits bladder cancer by promoting cell necroptosis.
Yang X, Zhang S, He J, Zhao L, Chen L, Yang Y, Wang J, Yan L, Zhang T
Clinical and experimental pharmacology & physiology 2023 Sep;50(9):738-748
Clinical and experimental pharmacology & physiology 2023 Sep;50(9):738-748
Activation of the TNF-α-Necroptosis Pathway in Parvalbumin-Expressing Interneurons of the Anterior Cingulate Cortex Contributes to Neuropathic Pain.
Duan Y, Li Q, Zhou Y, Chen S, Li Y, Zang Y
International journal of molecular sciences 2023 Oct 22;24(20)
International journal of molecular sciences 2023 Oct 22;24(20)
Intranasal inoculation of female BALB/c mice with replication-deficient human adenovirus type 5 expressing SARS-CoV-2 nucleocapsid protein aggravates lung pathology upon re-encountering the antigen.
Cao J, Gu H, Zhang X, Yun H, Li J, Si CY, Zhang J, Wang H
Virus research 2023 Oct 2;335:199201
Virus research 2023 Oct 2;335:199201
Polystyrene microplastics with different sizes induce the apoptosis and necroptosis in liver through the PTEN/PI3K/AKT/autophagy axis.
Wang S, Wu H, Shi X, Wang Y, Xu S
The Science of the total environment 2023 Nov 15;899:165461
The Science of the total environment 2023 Nov 15;899:165461
Deletion of Bak1 alleviates microglial necroptosis and neuroinflammation after experimental subarachnoid hemorrhage.
Qiu X, Tao Q, Zhang L, Kuang C, Xie Y, Zhang L, Yin S, Peng J, Jiang Y
Journal of neurochemistry 2023 Mar;164(6):829-846
Journal of neurochemistry 2023 Mar;164(6):829-846
Necroptosis signaling and mitochondrial dysfunction cross-talking facilitate cell death mediated by chelerythrine in glioma.
Wang P, Zheng SY, Jiang RL, Wu HD, Li YA, Lu JL, Xiong Y, Han B, Lin L
Free radical biology & medicine 2023 Jun;202:76-96
Free radical biology & medicine 2023 Jun;202:76-96
DBP induced autophagy and necrotic apoptosis in HepG2 cells via the mitochondrial damage pathway.
Liu H, Xu L, Zhou L, Han W, Li Z, Liu C
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jun;176:113782
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jun;176:113782
Polysaccharide from Strongylocentrotus nudus eggs regulates intestinal epithelial autophagy through CD36/PI3K-Akt pathway to ameliorate inflammatory bowel disease.
Zhou M, Zhi J, Zhi J, Xiong Z, Wu F, Lu Y, Hu Q
International journal of biological macromolecules 2023 Jul 31;244:125373
International journal of biological macromolecules 2023 Jul 31;244:125373
Inhibition of GSK3β activity alleviates acute liver failure via suppressing multiple programmed cell death.
Zhang D, Shi C, Zhang Q, Wang Y, Guo J, Gong Z
Journal of inflammation (London, England) 2023 Jul 13;20(1):24
Journal of inflammation (London, England) 2023 Jul 13;20(1):24
Caspofungin Suppresses Brain Cell Necroptosis in Ischemic Stroke Rats via Up-Regulation of Pellino3.
Zhang YY, Tian J, Peng ZM, Liu B, Peng YW, Zhang XJ, Hu ZY, Luo XJ, Peng J
Cardiovascular drugs and therapy 2023 Feb;37(1):9-23
Cardiovascular drugs and therapy 2023 Feb;37(1):9-23
Functional Characterization of a Familial ALS-Associated Missense TBK1 (p-Arg573Gly) Mutation in Patient-Derived Lymphoblasts.
Porras G, Ruiz S, Maestro I, Borrego-Hernández D, Redondo AG, Martínez A, Martín-Requero Á
International journal of molecular sciences 2023 Feb 2;24(3)
International journal of molecular sciences 2023 Feb 2;24(3)
N-acetylcysteine combined with insulin attenuates myocardial injury in canines with type 1 diabetes mellitus by modulating TNF-α-mediated apoptotic pathways and affecting linear ubiquitination.
Huang J, Pang X, Zhang X, Qiu W, Zhang X, Wang R, Xie W, Bai Y, Zhou S, Liao J, Xiong Z, Tang Z, Su R
Translational research : the journal of laboratory and clinical medicine 2023 Dec;262:1-11
Translational research : the journal of laboratory and clinical medicine 2023 Dec;262:1-11
Serinc2 deficiency exacerbates sepsis-induced cardiomyopathy by enhancing necroptosis and apoptosis.
Hu S, Huang M, Mao S, Yang M, Ju H, Liu Z, Cheng M, Wu G
Biochemical pharmacology 2023 Dec;218:115903
Biochemical pharmacology 2023 Dec;218:115903
Alcohol induces hepatocytes necroptosis through the LC3/RIPK1/RIPK3 pathway.
Chen Y, Liu M, Wei H, Guo J, Zhang S, Bu X, Chen S, Zhang D, Guan S
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Dec;182:114124
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Dec;182:114124
Baicalin suppressed necroptosis and inflammation against chlorpyrifos toxicity; involving in ER stress and oxidative stress in carp gills.
Li X, Bai Y, Bi Y, Wu Q, Xu S
Fish & shellfish immunology 2023 Aug;139:108883
Fish & shellfish immunology 2023 Aug;139:108883
[Dihydromyricetin alleviates pyroptosis and necroptosis in mice with MPTP-induced chronic Parkinson's disease by inducing autophagy].
Zhang M, Zhang Y, Niu M, Zhu Y, Tong S, Kou X
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Aug 20;43(8):1268-1278
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Aug 20;43(8):1268-1278
LncRNA NR_003508 Suppresses Mycobacterium tuberculosis-Induced Programmed Necrosis via Sponging miR-346-3p to Regulate RIPK1.
Liu L, Yu Z, Ma Q, Yu J, Gong Z, Deng G, Wu X
International journal of molecular sciences 2023 Apr 28;24(9)
International journal of molecular sciences 2023 Apr 28;24(9)
Role of SESTRIN2/AMPK/ULK1 pathway activation and lysosomes dysfunction in NaAsO(2)-induced liver injury under oxidative stress.
Bi D, Zheng D, Shi M, Hu Q, Wang H, Zhi H, Lou D, Zhang A, Hu Y
Ecotoxicology and environmental safety 2023 Apr 1;254:114751
Ecotoxicology and environmental safety 2023 Apr 1;254:114751
Necrosulfonamide Alleviates Acute Brain Injury of Intracerebral Hemorrhage via Inhibiting Inflammation and Necroptosis.
Zhang X, Zhang Y, Wang F, Liu Y, Yong VW, Xue M
Frontiers in molecular neuroscience 2022;15:916249
Frontiers in molecular neuroscience 2022;15:916249
A novel necroptosis-related gene index for predicting prognosis and a cold tumor immune microenvironment in stomach adenocarcinoma.
Khan M, Lin J, Wang B, Chen C, Huang Z, Tian Y, Yuan Y, Bu J
Frontiers in immunology 2022;13:968165
Frontiers in immunology 2022;13:968165
Paeoniflorin directly binds to TNFR1 to regulate podocyte necroptosis in diabetic kidney disease.
Wang X, Liu XQ, Jiang L, Huang YB, Zeng HX, Zhu QJ, Qi XM, Wu YG
Frontiers in pharmacology 2022;13:966645
Frontiers in pharmacology 2022;13:966645
Protective effect of inhibiting necroptosis on gentamicin-induced nephrotoxicity.
Hu BF, Gong Q, Chen SQ, Yue L, Ma WX, Wang F, Feng XW, Wang JN, Li C, Liu MM, Wang XF, Meng XM, Li J, Wen JG
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Sep;36(9):e22487
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Sep;36(9):e22487
Novel pharmacological inhibition of JMJD3 improves necrotizing enterocolitis by attenuating the inflammatory response and ameliorating intestinal injury.
Ma S, Xu L, Chen L, Sun X, Hu F, Gong Y, Yang R, Li J, Wang Q, Huang S, Zhou H, Wang J
Biochemical pharmacology 2022 Sep;203:115165
Biochemical pharmacology 2022 Sep;203:115165
Study of the synergistic effect of singlet oxygen with other plasma-generated ROS in fungi inactivation during water disinfection.
Xu H, Fang C, Shao C, Li L, Huang Q
The Science of the total environment 2022 Sep 10;838(Pt 4):156576
The Science of the total environment 2022 Sep 10;838(Pt 4):156576
Tea polyphenols alleviates acetochlor-induced apoptosis and necroptosis via ROS/MAPK/NF-κB signaling in Ctenopharyngodon idellus kidney cells.
Zhao X, Shi X, Liu Q, Li X
Aquatic toxicology (Amsterdam, Netherlands) 2022 May;246:106153
Aquatic toxicology (Amsterdam, Netherlands) 2022 May;246:106153
Myo-inositol oxygenase overexpression exacerbates cadmium-induced kidney injury via oxidant stress and necroptosis.
Zheng X, Deng F, Sharma I, Kanwar YS
American journal of physiology. Renal physiology 2022 Mar 1;322(3):F344-F359
American journal of physiology. Renal physiology 2022 Mar 1;322(3):F344-F359
Selenium Deficiency Induces Apoptosis and Necroptosis Through ROS/MAPK Signal in Human Uterine Smooth Muscle Cells.
Wang Y, Li X, Yao Y, Zhao X, Shi X, Cai Y
Biological trace element research 2022 Jul;200(7):3147-3158
Biological trace element research 2022 Jul;200(7):3147-3158
The protective effect of rabeprazole on cisplatin-induced apoptosis and necroptosis of renal proximal tubular cells.
Chen SQ, Hu BF, Yang YR, He Y, Yue L, Guo D, Wu TN, Feng XW, Li Q, Zhang W, Wen JG
Biochemical and biophysical research communications 2022 Jul 5;612:91-98
Biochemical and biophysical research communications 2022 Jul 5;612:91-98
Proteomic Mapping and Targeting of Mitotic Pericentriolar Material in Tumors Bearing Centrosome Amplification.
Xie B, Pu Y, Yang F, Chen W, Yue W, Ma J, Zhang N, Jiang Y, Wu J, Lin Y, Liang X, Wang C, Zou P, Li M
Cancer research 2022 Jul 18;82(14):2576-2592
Cancer research 2022 Jul 18;82(14):2576-2592
Combination of Compound Kushen Injection and cisplatin shows synergistic antitumor activity in p53-R273H/P309S mutant colorectal cancer cells through inducing apoptosis.
Wu X, Lu Y, Qin X
Journal of ethnopharmacology 2022 Jan 30;283:114690
Journal of ethnopharmacology 2022 Jan 30;283:114690
The role of KIAA1191 in the necroptotic pathway of multiple myeloma.
Xu Z, Sun Y, Jiang J, Liu P
Annals of hematology 2022 Feb;101(2):359-367
Annals of hematology 2022 Feb;101(2):359-367
Salmonella pSLT-encoded effector SpvB promotes RIPK3-dependent necroptosis in intestinal epithelial cells.
Dong K, Zhu Y, Deng Q, Sun L, Yang S, Huang K, Cao Y, Li Y, Wu S, Huang R
Cell death discovery 2022 Feb 2;8(1):44
Cell death discovery 2022 Feb 2;8(1):44
Therapeutic effects of JLX001 on neuronal necroptosis after cerebral ischemia-reperfusion in rats.
Li W, Gou X, Xu D, Zhou L, Li F, Ye A, Hu Y, Li Y
Experimental brain research 2022 Dec;240(12):3167-3182
Experimental brain research 2022 Dec;240(12):3167-3182
Targeting Cell Membranes, Depleting ROS by Dithiane and Thioketal-Containing Polymers with Pendant Cholesterols Delivering Necrostatin-1 for Glaucoma Treatment.
Rong R, Zhou X, Liang G, Li H, You M, Liang Z, Zeng Z, Xiao H, Ji D, Xia X
ACS nano 2022 Dec 27;16(12):21225-21239
ACS nano 2022 Dec 27;16(12):21225-21239
Developmental exposure to chlorpyrifos causes neuroinflammation via necroptosis in mouse hippocampus and human microglial cell line.
Tu Y, Yang Y, Wang Y, Wu N, Tao J, Yang G, You M
Environmental pollution (Barking, Essex : 1987) 2022 Dec 1;314:120217
Environmental pollution (Barking, Essex : 1987) 2022 Dec 1;314:120217
Biotransformation of graphene oxide within lung fluids could intensify its synergistic biotoxicity effect with cadmium by inhibiting cellular efflux of cadmium.
Zhu J, Liu L, Ma J, Fu Q, Zheng Z, Du E, Xu Y, Zhang Z
Environmental pollution (Barking, Essex : 1987) 2022 Aug 1;306:119421
Environmental pollution (Barking, Essex : 1987) 2022 Aug 1;306:119421
LncRNA HABON promoted liver cancer cells survival under hypoxia by inhibiting mPTP opening.
Wo L, Zhang X, Ma C, Zhou C, Li J, Hu Z, Gong X, Zhan M, He M, Zhao Q
Cell death discovery 2022 Apr 6;8(1):171
Cell death discovery 2022 Apr 6;8(1):171
Autophagy-Related LC3 Accumulation Interacted Directly With LIR Containing RIPK1 and RIPK3, Stimulating Necroptosis in Hypoxic Cardiomyocytes.
Huang Y, Feng Y, Cui L, Yang L, Zhang Q, Zhang J, Jiang X, Zhang X, Lv Y, Jia JZ, Zhang DX, Huang YS
Frontiers in cell and developmental biology 2021;9:679637
Frontiers in cell and developmental biology 2021;9:679637
Astragalin Protects against Spinal Cord Ischemia Reperfusion Injury through Attenuating Oxidative Stress-Induced Necroptosis.
Sun F, Zhang H, Shi J, Huang T, Wang Y
BioMed research international 2021;2021:7254708
BioMed research international 2021;2021:7254708
Yi-Qi-Jian-Pi Formula Suppresses RIPK1/RIPK3-Complex-Dependent Necroptosis of Hepatocytes Through ROS Signaling and Attenuates Liver Injury in Vivo and in Vitro.
Wang F, Tang L, Liang B, Jin C, Gao L, Li Y, Li Z, Shao J, Zhang Z, Tan S, Zhang F, Zheng S
Frontiers in pharmacology 2021;12:658811
Frontiers in pharmacology 2021;12:658811
Pterostilbene attenuates RIPK3-dependent hepatocyte necroptosis in alcoholic liver disease via SIRT2-mediated NFATc4 deacetylation.
Shao Y, Wang X, Zhou Y, Jiang Y, Wu R, Lu C
Toxicology 2021 Sep;461:152923
Toxicology 2021 Sep;461:152923
Protective action of ultrasound-guided intraparenchymal transplantation of BMSCs in adriamycin nephropathy rats through the RIPK3/MLKL and NLRP3 pathways.
Xia C, Shao L, Ma Y, Wang X, Zhang Y, Shi C, Li J, Zhang W, Li H, Wang J
Acta histochemica 2021 Oct;123(7):151773
Acta histochemica 2021 Oct;123(7):151773
Ultrasound-Guided Transplantation of Mesenchymal Stem Cells Improves Adriamycin Nephropathy in Rats Through the RIPK3/MLKL and TLR-4/NF-κB Signaling.
Xia C, Shao L, Ma Y, Wang X, Zhang Y, Shi C, Li H, Wang J
Stem cells and development 2021 Oct 15;30(20):1003-1016
Stem cells and development 2021 Oct 15;30(20):1003-1016
Pterocephin A, a novel Triterpenoid Saponin from Pterocephalus hookeri induced liver injury by activation of necroptosis.
Wang R, Wei L, Dong Z, Meng F, Wang G, Zhou S, Lan X, Liao Z, Chen M
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 May;85:153548
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 May;85:153548
Methamphetamine exposure induces neuronal programmed necrosis by activating the receptor-interacting protein kinase 3 -related signalling pathway.
Zhao X, Lu J, Chen X, Gao Z, Zhang C, Chen C, Qiao D, Wang H
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 May;35(5):e21561
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 May;35(5):e21561
Lansoprazole promotes cisplatin-induced acute kidney injury via enhancing tubular necroptosis.
Ye L, Pang W, Huang Y, Wu H, Huang X, Liu J, Wang S, Yang C, Pan Q, Liu H
Journal of cellular and molecular medicine 2021 Mar;25(5):2703-2713
Journal of cellular and molecular medicine 2021 Mar;25(5):2703-2713
Utilizing an Animal Model to Identify Brain Neurodegeneration-Related Biomarkers in Aging.
Yang MH, Chen YA, Tu SC, Chi PL, Chuang KP, Chang CC, Lee CH, Chen YL, Lee CH, Yuan CH, Tyan YC
International journal of molecular sciences 2021 Mar 23;22(6)
International journal of molecular sciences 2021 Mar 23;22(6)
Deficiency of NEAT1 prevented MPP(+)-induced inflammatory response, oxidative stress and apoptosis in dopaminergic SK-N-SH neuroblastoma cells via miR-1277-5p/ARHGAP26 axis.
Zhou S, Zhang D, Guo J, Chen Z, Chen Y, Zhang J
Brain research 2021 Jan 1;1750:147156
Brain research 2021 Jan 1;1750:147156
The Performance of HepG2 and HepaRG Systems through the Glass of Acetaminophen-Induced Toxicity.
Lőrincz T, Deák V, Makk-Merczel K, Varga D, Hajdinák P, Szarka A
Life (Basel, Switzerland) 2021 Aug 21;11(8)
Life (Basel, Switzerland) 2021 Aug 21;11(8)
Traditional herbal formula Wu-Mei-Wan alleviates TNBS-induced colitis in mice by inhibiting necroptosis through increasing RIPK3 O-GlcNAcylation.
Wu F, Shao Q, Cheng Z, Xiong X, Fang K, Zhao Y, Dong R, Xu L, Lu F, Chen G
Chinese medicine 2021 Aug 16;16(1):78
Chinese medicine 2021 Aug 16;16(1):78
Cadmium exposure induces TNF-α-mediated necroptosis via FPR2/TGF-β/NF-κB pathway in swine myocardium.
Zhao X, Wang S, Li X, Liu H, Xu S
Toxicology 2021 Apr 15;453:152733
Toxicology 2021 Apr 15;453:152733
The Herbal Medicine Scutellaria-Coptis Alleviates Intestinal Mucosal Barrier Damage in Diabetic Rats by Inhibiting Inflammation and Modulating the Gut Microbiota.
Zhang B, Yue R, Chen Y, Huang X, Yang M, Shui J, Peng Y
Evidence-based complementary and alternative medicine : eCAM 2020;2020:4568629
Evidence-based complementary and alternative medicine : eCAM 2020;2020:4568629
Jia-Ji Electro-Acupuncture Improves Locomotor Function With Spinal Cord Injury by Regulation of Autophagy Flux and Inhibition of Necroptosis.
Hongna Y, Hongzhao T, Quan L, Delin F, Guijun L, Xiaolin L, Fulin G, Zhongren S
Frontiers in neuroscience 2020;14:616864
Frontiers in neuroscience 2020;14:616864
M10, a Myricetin-3-O-b-D-Lactose Sodium Salt, Prevents Ulcerative Colitis Through Inhibiting Necroptosis in Mice.
Zhou XL, Yang J, Qu XJ, Meng J, Miao RR, Cui SX
Frontiers in pharmacology 2020;11:557312
Frontiers in pharmacology 2020;11:557312
Combination of Rapamycin and MK-2206 Induced Cell Death via Autophagy and Necroptosis in MYCN-Amplified Neuroblastoma Cell Lines.
Dong Y, Gong W, Hua Z, Chen B, Zhao G, Liu Z, Thiele CJ, Li Z
Frontiers in pharmacology 2020;11:31
Frontiers in pharmacology 2020;11:31
Protective effect of astaxanthin against SnS(2) nanoflowers induced testes toxicity by suppressing RIPK1-RIPK3-MLKL signaling in mice.
Yuan L, Liang P, Qu Y, An T, Wang J, Deng X, Bai L, Shen P, Bai D
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2020 Nov;145:111736
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2020 Nov;145:111736
Acetylharpagide Protects Mice from Staphylococcus Aureus-Induced Acute Lung Injury by Inhibiting NF-κB Signaling Pathway.
Zhang Z, Wang Y, Shan Y, Yin W
Molecules (Basel, Switzerland) 2020 Nov 25;25(23)
Molecules (Basel, Switzerland) 2020 Nov 25;25(23)
Necroptosis mediated by impaired autophagy flux contributes to adverse ventricular remodeling after myocardial infarction.
Zhang H, Yin Y, Liu Y, Zou G, Huang H, Qian P, Zhang G, Zhang J
Biochemical pharmacology 2020 May;175:113915
Biochemical pharmacology 2020 May;175:113915
A new perspective of triptolide-associated hepatotoxicity: the relevance of NF- κ B and NF- κ B-mediated cellular FLICE-inhibitory protein.
Yuan Z, Yuan Z, Hasnat M, Zhang H, Liang P, Sun L, Jiang Z, Zhang L
Acta pharmaceutica Sinica. B 2020 May;10(5):861-877
Acta pharmaceutica Sinica. B 2020 May;10(5):861-877
New insights in acetaminophen toxicity: HMGB1 contributes by itself to amplify hepatocyte necrosis in vitro through the TLR4-TRIF-RIPK3 axis.
Minsart C, Liefferinckx C, Lemmers A, Dressen C, Quertinmont E, Leclercq I, Devière J, Moreau R, Gustot T
Scientific reports 2020 Mar 27;10(1):5557
Scientific reports 2020 Mar 27;10(1):5557
Insights into mechanisms of pranoprofen-induced apoptosis and necroptosis in human corneal stromal cells.
Lin Y, Yu M, Fan T
Toxicology letters 2020 Mar 1;320:9-18
Toxicology letters 2020 Mar 1;320:9-18
Raman micro-spectroscopy monitoring of cytochrome c redox state in Candida utilis during cell death under low-temperature plasma-induced oxidative stress.
Chen Z, Liu J, Tian L, Zhang Q, Guan Y, Chen L, Liu G, Yu HQ, Tian Y, Huang Q
The Analyst 2020 Jun 7;145(11):3922-3930
The Analyst 2020 Jun 7;145(11):3922-3930
SETDB1-Mediated Cell Fate Transition between 2C-Like and Pluripotent States.
Wu K, Liu H, Wang Y, He J, Xu S, Chen Y, Kuang J, Liu J, Guo L, Li D, Shi R, Shen L, Wang Y, Zhang X, Wang J, Pei D, Chen J
Cell reports 2020 Jan 7;30(1):25-36.e6
Cell reports 2020 Jan 7;30(1):25-36.e6
Chidamide induces necroptosis via regulation of c‑FLIPL expression in Jurkat and HUT‑78 cells.
Chi Z, Gao H, Liu H, Wu B, Zhang B, Gu M, Yang W
Molecular medicine reports 2020 Feb;21(2):936-944
Molecular medicine reports 2020 Feb;21(2):936-944
Norfloxacin induces apoptosis and necroptosis in human corneal epithelial cells.
Yang T, Fan TJ, Xu B
Toxicology in vitro : an international journal published in association with BIBRA 2020 Aug;66:104868
Toxicology in vitro : an international journal published in association with BIBRA 2020 Aug;66:104868
ZYZ-803 Mitigates Endoplasmic Reticulum Stress-Related Necroptosis after Acute Myocardial Infarction through Downregulating the RIP3-CaMKII Signaling Pathway.
Chang L, Wang Z, Ma F, Tran B, Zhong R, Xiong Y, Dai T, Wu J, Xin X, Guo W, Xie Y, Mao Y, Zhu YZ
Oxidative medicine and cellular longevity 2019;2019:6173685
Oxidative medicine and cellular longevity 2019;2019:6173685
The role of the LncRNA-FA2H-2-MLKL pathway in atherosclerosis by regulation of autophagy flux and inflammation through mTOR-dependent signaling.
Guo FX, Wu Q, Li P, Zheng L, Ye S, Dai XY, Kang CM, Lu JB, Xu BM, Xu YJ, Xiao L, Lu ZF, Bai HL, Hu YW, Wang Q
Cell death and differentiation 2019 Sep;26(9):1670-1687
Cell death and differentiation 2019 Sep;26(9):1670-1687
Necrostatin-1 Attenuates Renal Ischemia and Reperfusion Injury via Meditation of HIF-1α/mir-26a/TRPC6/PARP1 Signaling.
Shen B, Mei M, Pu Y, Zhang H, Liu H, Tang M, Pan Q, He Y, Wu X, Zhao H
Molecular therapy. Nucleic acids 2019 Sep 6;17:701-713
Molecular therapy. Nucleic acids 2019 Sep 6;17:701-713
High glucose-induced apoptosis and necroptosis in podocytes is regulated by UCHL1 via RIPK1/RIPK3 pathway.
Xu Y, Gao H, Hu Y, Fang Y, Qi C, Huang J, Cai X, Wu H, Ding X, Zhang Z
Experimental cell research 2019 Sep 15;382(2):111463
Experimental cell research 2019 Sep 15;382(2):111463
Quetiapine induces myocardial necroptotic cell death through bidirectional regulation of cannabinoid receptors.
Li X, Peng Z, Zhou Y, Wang J, Lin X, Dong X, Liu X, Jiang J, Jiang Y, Li L
Toxicology letters 2019 Oct 1;313:77-90
Toxicology letters 2019 Oct 1;313:77-90
Evaluation of the Liver Toxicity of Pterocephalus hookeri Extract via Triggering Necrosis.
Wang R, Dong Z, Zhang X, Mao J, Meng F, Lan X, Liao Z, Chen M
Toxins 2019 Mar 2;11(3)
Toxins 2019 Mar 2;11(3)
Gallic acid protects against ethanol-induced hepatocyte necroptosis via an NRF2-dependent mechanism.
Zhou Y, Jin H, Wu Y, Chen L, Bao X, Lu C
Toxicology in vitro : an international journal published in association with BIBRA 2019 Jun;57:226-232
Toxicology in vitro : an international journal published in association with BIBRA 2019 Jun;57:226-232
Dexmedetomidine Preconditioning Protects Cardiomyocytes Against Hypoxia/Reoxygenation-Induced Necroptosis by Inhibiting HMGB1-Mediated Inflammation.
Chen J, Jiang Z, Zhou X, Sun X, Cao J, Liu Y, Wang X
Cardiovascular drugs and therapy 2019 Feb;33(1):45-54
Cardiovascular drugs and therapy 2019 Feb;33(1):45-54
A new perspective of triptolide-associated hepatotoxicity: Liver hypersensitivity upon LPS stimulation.
Yuan Z, Zhang H, Hasnat M, Ding J, Chen X, Liang P, Sun L, Zhang L, Jiang Z
Toxicology 2019 Feb 15;414:45-56
Toxicology 2019 Feb 15;414:45-56
The Interrelationship of Pharmacologic Ascorbate Induced Cell Death and Ferroptosis.
Lőrincz T, Holczer M, Kapuy O, Szarka A
Pathology oncology research : POR 2019 Apr;25(2):669-679
Pathology oncology research : POR 2019 Apr;25(2):669-679
Neferine, a Bisbenzylisoquinoline Alkaloid, Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis.
Wu X, Guo Y, Min X, Pei L, Chen X
The American journal of Chinese medicine 2018;46(6):1263-1279
The American journal of Chinese medicine 2018;46(6):1263-1279
Necrostatin-1 promotes ectopic periodontal tissue like structure regeneration in LPS-treated PDLSCs.
Yan B, Zhang H, Dai T, Gu Y, Qiu X, Hu C, Liu Y, Wei K, Li D
PloS one 2018;13(11):e0207760
PloS one 2018;13(11):e0207760
Curcumol induces RIPK1/RIPK3 complex-dependent necroptosis via JNK1/2-ROS signaling in hepatic stellate cells.
Jia Y, Wang F, Guo Q, Li M, Wang L, Zhang Z, Jiang S, Jin H, Chen A, Tan S, Zhang F, Shao J, Zheng S
Redox biology 2018 Oct;19:375-387
Redox biology 2018 Oct;19:375-387
Trail armed oncolytic poxvirus suppresses lung cancer cell by inducing apoptosis.
Hu J, Wang H, Gu J, Liu X, Zhou X
Acta biochimica et biophysica Sinica 2018 Oct 1;50(10):1018-1027
Acta biochimica et biophysica Sinica 2018 Oct 1;50(10):1018-1027
Airn Regulates Igf2bp2 Translation in Cardiomyocytes.
Hosen MR, Militello G, Weirick T, Ponomareva Y, Dassanayaka S, Moore JB 4th, Döring C, Wysoczynski M, Jones SP, Dimmeler S, Uchida S
Circulation research 2018 May 11;122(10):1347-1353
Circulation research 2018 May 11;122(10):1347-1353
Receptor-Interacting Protein 3/Caspase-8 May Regulate Inflammatory Response and Promote Tissue Regeneration in the Periodontal Microenvironment.
Yan B, Wei K, Hou L, Dai T, Gu Y, Qiu X, Chen J, Feng Y, Cheng H, Yu Z, Zhang Y, Zhang H, Li D
Medical science monitor : international medical journal of experimental and clinical research 2018 Jul 29;24:5247-5257
Medical science monitor : international medical journal of experimental and clinical research 2018 Jul 29;24:5247-5257
MicroRNA-326 sensitizes human glioblastoma cells to curcumin via the SHH/GLI1 signaling pathway.
Yin S, Du W, Wang F, Han B, Cui Y, Yang D, Chen H, Liu D, Liu X, Zhai X, Jiang C
Cancer biology & therapy 2018 Apr 3;19(4):260-270
Cancer biology & therapy 2018 Apr 3;19(4):260-270
Dihydrotanshinone I, a natural product, ameliorates DSS-induced experimental ulcerative colitis in mice.
Guo Y, Wu X, Wu Q, Lu Y, Shi J, Chen X
Toxicology and applied pharmacology 2018 Apr 1;344:35-45
Toxicology and applied pharmacology 2018 Apr 1;344:35-45
Regulation of RIPK1 activation by TAK1-mediated phosphorylation dictates apoptosis and necroptosis.
Geng J, Ito Y, Shi L, Amin P, Chu J, Ouchida AT, Mookhtiar AK, Zhao H, Xu D, Shan B, Najafov A, Gao G, Akira S, Yuan J
Nature communications 2017 Aug 25;8(1):359
Nature communications 2017 Aug 25;8(1):359
The Machado-Joseph Disease Deubiquitinase Ataxin-3 Regulates the Stability and Apoptotic Function of p53.
Liu H, Li X, Ning G, Zhu S, Ma X, Liu X, Liu C, Huang M, Schmitt I, Wüllner U, Niu Y, Guo C, Wang Q, Tang TS
PLoS biology 2016 Nov;14(11):e2000733
PLoS biology 2016 Nov;14(11):e2000733
The ORF3 Protein of Genotype 1 Hepatitis E Virus Suppresses TLR3-induced NF-κB Signaling via TRADD and RIP1.
He M, Wang M, Huang Y, Peng W, Zheng Z, Xia N, Xu J, Tian D
Scientific reports 2016 Jun 8;6:27597
Scientific reports 2016 Jun 8;6:27597
Gelatin promotes murine fibrosarcoma L929 cell detachment and protects the cells from TNFα-induced cytotoxicity.
Wang HJ, Li MQ, Liu W, Yao GD, Xia MY, Hayashi T, Fujisaki H, Hattori S, Tashiro S, Onodera S, Ikejima T
Connective tissue research 2016 Jul;57(4):262-9
Connective tissue research 2016 Jul;57(4):262-9
Nicotine Induced Murine Spermatozoa Apoptosis via Up-Regulation of Deubiquitinated RIP1 by Trim27 Promoter Hypomethylation.
Nie D, Zhang D, Dai J, Zhang M, Zhao X, Xu W, Chen Z, Wang L, Wang Z, Qiao Z
Biology of reproduction 2016 Feb;94(2):31
Biology of reproduction 2016 Feb;94(2):31
Nrf2 Knockdown Disrupts the Protective Effect of Curcumin on Alcohol-Induced Hepatocyte Necroptosis.
Lu C, Xu W, Zhang F, Shao J, Zheng S
Molecular pharmaceutics 2016 Dec 5;13(12):4043-4053
Molecular pharmaceutics 2016 Dec 5;13(12):4043-4053
Type I collagen gel protects murine fibrosarcoma L929 cells from TNFα-induced cell death.
Wang HJ, He WQ, Chen L, Liu WW, Xu Q, Xia MY, Hayashi T, Fujisaki H, Hattori S, Tashiro S, Onodera S, Ikejima T
Biochemical and biophysical research communications 2015 Feb 20;457(4):693-9
Biochemical and biophysical research communications 2015 Feb 20;457(4):693-9
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- NIH/3T3 cells were subjected to SDS PAGE followed by western blot with 17519-1-AP(RIPK1-Specific antibody) at dilution of 1:300
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The RIPK1-Specific antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human RIPK1-Specific. This antibody recognizes human,mouse,rat antigen. The RIPK1-Specific antibody has been validated for the following applications: ELISA, WB, IF, IP, IHC analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-RIPK1-Specific (IP:17519-1-AP, 4ug; Detection:17519-1-AP 1:300) with HeLa cells lysate 2000ug.
- Sample type
- cell line
