AB-294-NA

antibody from Novus Biologicals

Targeting: HGF DFNB39, F-TCF, HGFB, HPTA, SF

Western blot (Data presented on provider website)

Blocking/Neutralizing (Supportive data in Antibodypedia)

Antibody Data

Product number

AB-294-NA

Provider

Novus Biologicals

Product name

Goat Polyclonal HGF Antibody

Antibody type

Polyclonal

References

Submitted references

Hepatocyte growth factor produced in lung fibroblasts enhances non-small cell lung cancer cell survival and tumor progression.

Kanaji N, Yokohira M, Nakano-Narusawa Y, Watanabe N, Imaida K, Kadowaki N, Bandoh S
Respiratory research 2017 Jun 15;18(1):118

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c-Met-mediated endothelial plasticity drives aberrant vascularization and chemoresistance in glioblastoma.

Huang M, Liu T, Ma P, Mitteer RA Jr, Zhang Z, Kim HJ, Yeo E, Zhang D, Cai P, Li C, Zhang L, Zhao B, Roccograndi L, O'Rourke DM, Dahmane N, Gong Y, Koumenis C, Fan Y
The Journal of clinical investigation 2016 May 2;126(5):1801-14

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A role for calcium-calmodulin in regulating nitric oxide production during skeletal muscle satellite cell activation.

Tatsumi R, Wuollet AL, Tabata K, Nishimura S, Tabata S, Mizunoya W, Ikeuchi Y, Allen RE
American journal of physiology. Cell physiology 2009 Apr;296(4):C922-9

Blocking/Neutralizing

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

IL-11 Secretion Induced by HGF and Neutralization by Human HGF Antibody. Recombinant Human HGF (Catalog # 294-HGN) induces IL-11 secretion in the Saos-2 human osteosarcoma cell line. The dose-dependent response (orange line) is measured by the Human IL-11 Duoset (Catalog # DY218). Under these conditions, IL-11 secretion elicited by HGF is neutralized (green line) by increasing concentrations of Goat Anti-Human HGF Antigen Affinity-purified Polyclonal Antibody (Catalog # AF-294-NA). The ND₅₀ is typically <2 μg/mL.