10150-2-AP
antibody from Proteintech Group
Targeting: GNAS
GNAS1, GNASXL, GPSA, NESP, NESP55, SCG6, SgVI
Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 10150-2-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10150-2-AP, RRID:AB_2111668
- Product name
- GNAS antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated GNAS antibody (Cat. #10150-2-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references A framework for Frizzled-G protein coupling and implications to the PCP signaling pathways.
Activation of melanocortin-1 receptor signaling in melanoma cells impairs T cell infiltration to dampen antitumor immunity.
Association of elevated autoantibody to high expression of GNAS in hepatocellular carcinoma.
GNAS promotes inflammation-related hepatocellular carcinoma progression by promoting STAT3 activation.
A novel GNAS-mutated human induced pluripotent stem cell model for understanding GNAS-mutated tumors.
Ablation of Gsa impairs renal tubule proliferation after injury via CDK2/cyclin E.
Gq activity- and β-arrestin-1 scaffolding-mediated ADGRG2/CFTR coupling are required for male fertility.
HDAC2 and TXNL1 distinguish aneuploid from diploid colorectal cancers.
Zhang Z, Lin X, Wei L, Wu Y, Xu L, Wu L, Wei X, Zhao S, Zhu X, Xu F
Cell discovery 2024 Jan 5;10(1):3
Cell discovery 2024 Jan 5;10(1):3
Activation of melanocortin-1 receptor signaling in melanoma cells impairs T cell infiltration to dampen antitumor immunity.
Cui Y, Miao Y, Cao L, Guo L, Cui Y, Yan C, Zeng Z, Xu M, Han T
Nature communications 2023 Sep 15;14(1):5740
Nature communications 2023 Sep 15;14(1):5740
Association of elevated autoantibody to high expression of GNAS in hepatocellular carcinoma.
Wang K, Qiu C, Xing M, Li M, Wang B, Ye H, Shi J, Dai L, Wang X, Wang P
Heliyon 2023 Dec;9(12):e22627
Heliyon 2023 Dec;9(12):e22627
GNAS promotes inflammation-related hepatocellular carcinoma progression by promoting STAT3 activation.
Ding H, Zhang X, Su Y, Jia C, Dai C
Cellular & molecular biology letters 2020;25:8
Cellular & molecular biology letters 2020;25:8
A novel GNAS-mutated human induced pluripotent stem cell model for understanding GNAS-mutated tumors.
Watanabe K, Nakamura T, Onodera S, Saito A, Shibahara T, Azuma T
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2020 Sep;42(9):1010428320962588
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2020 Sep;42(9):1010428320962588
Ablation of Gsa impairs renal tubule proliferation after injury via CDK2/cyclin E.
Liu L, Deng Y, Cai Y, Lu P, Guo Y, Zhang C, Li Q, Zhang T, Han M, Xu G
American journal of physiology. Renal physiology 2020 Mar 1;318(3):F793-F803
American journal of physiology. Renal physiology 2020 Mar 1;318(3):F793-F803
Gq activity- and β-arrestin-1 scaffolding-mediated ADGRG2/CFTR coupling are required for male fertility.
Zhang DL, Sun YJ, Ma ML, Wang YJ, Lin H, Li RR, Liang ZL, Gao Y, Yang Z, He DF, Lin A, Mo H, Lu YJ, Li MJ, Kong W, Chung KY, Yi F, Li JY, Qin YY, Li J, Thomsen ARB, Kahsai AW, Chen ZJ, Xu ZG, Liu M, Li D, Yu X, Sun JP
eLife 2018 Feb 2;7
eLife 2018 Feb 2;7
HDAC2 and TXNL1 distinguish aneuploid from diploid colorectal cancers.
Gemoll T, Roblick UJ, Szymczak S, Braunschweig T, Becker S, Igl BW, Bruch HP, Ziegler A, Hellman U, Difilippantonio MJ, Ried T, Jörnvall H, Auer G, Habermann JK
Cellular and molecular life sciences : CMLS 2011 Oct;68(19):3261-74
Cellular and molecular life sciences : CMLS 2011 Oct;68(19):3261-74
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The GNAS antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human GNAS. This antibody recognizes human,mouse,rat antigen. The GNAS antibody has been validated for the following applications: ELISA, WB analysis.