Antibody data
- Antibody Data
- Antigen structure
- References [156]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 15365-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15365-1-AP, RRID:AB_2123037
- Product name
- IFN Gamma antibody
- Antibody type
- Polyclonal
- Description
- IFN Gamma antibody (Cat. #15365-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Huzhang-Xiangbaji compounds enhance the repair of meniscal cartilage by inhibiting ferroptosis and inflammatory microenvironment.
Potential effect and mechanism of ultrashort wave therapy in mice with chronic rhinosinusitis.
ITK-targeted immune remodeling enhanced the efficacy of anti-CD19 CAR-T cell therapy.
Capsular Polysaccharide of Lactiplantibacillus plantarum DPUL F232 Alleviates Whey Protein Allergy by Regulating Immunity, Gut Microbiota, and Production of SCFAs.
Bie-Jia-Jian Pill: Inhibiting tumor glycolysis and promoting CD8(+) cell-mediated anti-tumor immunity by targeting HIF-1α-PI3K/AKT/mTOR and CCL20 in hepatocellular carcinoma.
CD80-Mediated T-Cell Suppression by Cancer Stem-like Cells in Head and Neck Squamous Cell Carcinoma.
Caffeine inhibited the hyperoxia-induced A2AR-ERK/p38 MAPK-IL-8 pathway in type II alveolar epithelial cells to suppress NETs formation in bronchopulmonary dysplasia.
Astrocytic BDNF Modulates Sensitivity to Stress-Induced Anxiety-Like Behaviors.
Oncolytic adenovirus H101 enhances the anti-tumor effects of PD-1 blockade via CD47 downregulation in tumor cells.
Ultrasound-Targeted Nanobubbles Codelivering NKP-1339 and miR-142-5p for Synergistic Mitochondrial Immunogenic Cell Death and PD-L1 Inhibition in Cancer Therapy.
Overexpression of Decorin Optimizes the Treatment Efficacy of Umbilical Cord Mesenchymal Stem Cells in Bleomycin-Induced Pulmonary Fibrosis in Rats.
Integrating cuproptosis- and ferroptosis-related gene signatures to predict prognosis, immunotherapy response, and drug sensitivity in patients with skin cutaneous melanoma.
Itraconazole inhibits the Wnt/β-catenin signaling pathway to induce tumor-associated macrophages polarization to enhance the efficacy of immunotherapy in endometrial cancer.
Mature tertiary lymphoid structure associated CD103+ CD8+ Trm cells determined improved anti-tumor immune in breast cancer.
Bacterial cellulose membrane integrating phase-transited lysozyme nanofilm loaded with biguanides for dressing treatment of atopic dermatitis.
Epigenetic suppression of Nrf2-Slc40a1 axis induces ferroptosis and enhances immunotherapy in pancreatic cancer.
A STAT1-GBP3-STING positive feedback loop governs inflammation, oxidative stress, and DNA damage to trigger acute aortic dissection.
Efferocytosis-related signatures identified via Single-cell analysis and machine learning predict TNBC outcomes and immunotherapy response.
A matrix stiffness gene signature identifies SLC20A1 as a novel mechano-immunological checkpoint enabling synergistic immunotherapy in pancreatic ductal adenocarcinoma.
Analysis of differential transcriptome expression reveals that ISG15 provides support for embryo development by promoting angiogenesis in porcine mesometrium.
Targeting KMT5C Suppresses Lung Cancer Progression and Enhances the Efficacy of Immunotherapy.
Drug-loaded microneedle patches containing regulatory T cell-derived exosomes for psoriasis treatment.
Pectin/caffeic acid nanoparticles in a poloxamer thermosensitive gel for the treatment of ulcerative colitis by inhibiting cGAS-STING pathway.
Chemotherapy boosts anti-angiogenic and anti-PD-1 combination therapy through activation of cCAS-STING pathway in colon cancer.
Sorafenib-loaded metal-organic framework nanoparticles for anti-hepatocellular carcinoma effects through synergistically potentiating ferroptosis and remodeling tumor immune microenvironment.
Effect of COL11A1 on oral squamous cell carcinoma.
Design, synthesis and bioevaluation of novel hydrazide derivatives as enhancers of immunotherapy and DNA-damage response in antitumor therapy.
Causal genes identification of giant cell arteritis in CD4+ Memory t cells: an integration of multi-omics and expression quantitative trait locus analysis.
PD-L1 and IFN-γ modulate Non-Small Cell Lung Cancer (NSCLC) cell plasticity associated to immune checkpoint inhibitor (ICI)-mediated hyperprogressive disease (HPD).
Time-series single-cell transcriptomic profiling of luteal-phase endometrium uncovers dynamic characteristics and its dysregulation in recurrent implantation failures.
IFNγ regulates ferroptosis in KFs by inhibiting the expression of SPOCD1 through DNMT3A.
Intra-cisterna-magna bevacizumab injection (ICM-BI) reproduces pathological alterations of cerebral small vessel diseases.
Molecular Subtyping and Therapeutic Targeting of IFNG-Driven Immunogenic Cell Death in Lung Adenocarcinoma.
Targeting Deltex E3 Ubiquitin Ligase 2 Inhibits Tumor-associated Neutrophils and Sensitizes Hepatocellular Carcinoma Cells to Immunotherapy.
LncRNA RNF144A-AS1 gene polymorphisms and their influence on lung cancer patients in the Chinese Han population.
Reductive Adjuvant Nanosystem for Alleviated Atopic Dermatitis Syndromes.
IFN-γ-mediated inhibition of JAK/STAT signaling via nano-scutellarin treatment is an efficient strategy for ameliorating liver fibrosis.
Deletion of the African swine fever virus E120R gene completely attenuates its virulence by enhancing host innate immunity and impairing virus release.
Prognostic value of LPAR1 expression and methylation in low-grade gliomas: a meta-analysis of TCGA and CGGA datasets and functional validation.
Radiotherapy Combined with Immune Checkpoint Inhibitor on Murine Fibrosarcoma and a Narrative Review of Clinical Studies.
Gestational and Lactational Exposure to BPS Triggers Microglial Ferroptosis via the SLC7A11/GPX4 Antioxidant Axis and Induces Memory Impairment in Offspring Mice.
Elevated Body Mass Index Aggravates Histopathological Changes and Postoperative Recurrence Risk in Nasal Polyps.
Abnormal miR-122-5p expression in decidual NK cells and its impact on trophoblast behavior: insights into unexplained recurrent pregnancy loss.
Neoadjuvant immunochemotherapy improves clinical outcomes of patients with esophageal cancer by mediating anti-tumor immunity of CD8+ T (Tc1) and CD16+ NK cells.
Construction of disulfidptosis-based immune response prediction model with artificial intelligence and validation of the pivotal grouping oncogene c-MET in regulating T cell exhaustion.
Mechanism of Lian Hua Qing Wen capsules regulates the inflammatory response caused by M(1) macrophage based on cellular experiments and computer simulations.
Vimentin, inversely correlating with infiltration of CD8 + T lymphocytes, promotes nuclear translocation of PD-L1 in esophageal squamous cell carcinoma.
Corynebacterium parakroppenstedtii secretes a novel glycolipid to promote the development of granulomatous lobular mastitis.
Chaperonin-containing TCP1 subunit 6A inhibition via TRIM21-mediated K48-linked ubiquitination suppresses triple-negative breast cancer progression through the AKT signalling pathway.
IFN-γ derived from activated human CD4(+) T cells inhibits the replication of SARS-CoV-2 depending on cell-type and viral strain.
Targeting AQP9 enhanced the anti-TNF therapy response in Crohn's disease by inhibiting LPA-hippo pathway.
Implications of IFNγ SNP rs2069705 in primary Sjögren's syndrome: transcriptional activation and B cell infiltration.
Transcutaneous Auricular Vagus Nerve Stimulation Alleviates Monobenzone-Induced Vitiligo in Mice.
The construction of modular universal chimeric antigen receptor T (MU-CAR-T) cells by covalent linkage of allogeneic T cells and various antibody fragments.
Pan-Cancer Single-Cell and Spatial-Resolved Profiling Reveals the Immunosuppressive Role of APOE+ Macrophages in Immune Checkpoint Inhibitor Therapy.
Interferon Gamma Induces Higher Neutrophil Extracellular Traps Leading to Tumor-Killing Activity in Microsatellite Stable Colorectal Cancer.
Comprehensive molecular characterization of long-term glioblastoma survivors.
Cell fusion upregulates PD-L1 expression for evasion from immunosurveillance.
An oncolytic system produces oxygen selectively in pancreatic tumor cells to alleviate hypoxia and improve immune activation.
Increased S. aureus colonization and reduced antimicrobial peptide expression in erythrodermic psoriasis.
A High MCT-Based Ketogenic Diet Suppresses Th1 and Th17 Responses to Ameliorate Experimental Autoimmune Encephalomyelitis in Mice by Inhibiting GSDMD and JAK2-STAT3/4 Pathways.
The Identification of Gamma-Glutamyl Hydrolase in Uterine Corpus Endometrial Carcinoma: a Predictive Model and Machine Learning.
Targeting CD38/ ADP-ribosyl cyclase as a novel therapeutic strategy for identification of three potent agonists for leukopenia treatment.
Blockade of C5a receptor unleashes tumor-associated macrophage antitumor response and enhances CXCL9-dependent CD8(+) T cell activity.
ATP6AP1 as a potential prognostic biomarker in CRC by comprehensive analysis and verification.
L-lysine supplementation attenuates experimental autoimmune hepatitis in a chronic murine model.
STING Activation in Macrophages and Microglia Drives Poststroke Inflammation: Implications for Neuroinflammatory Mechanisms and Therapeutic Interventions.
EVA1B facilitates esophageal squamous carcinoma progression and recruitment of immunosuppressive myeloid-derived suppressor cells in the tumor microenvironment.
The plant extract PNS mitigates atherosclerosis via promoting Nrf2-mediated inhibition of ferroptosis through reducing USP2-mediated Keap1 deubiquitination.
NPSR1 promotes chronic colitis through regulating CD4(+) T cell effector function in inflammatory bowel disease.
Anti-ulcerative colitis effect of rotating magnetic field on DSS-induced mice by modulating colonic inflammatory deterioration.
Exploring the mechanism of Lianhuaqingwen (LHQW) in treating chronic bronchitis based on network pharmacology and experimental validation.
Multi-regulatory potency of USP1 on inflammasome components promotes pyroptosis in thyroid follicular cells and contributes to the progression of Hashimoto's thyroiditis.
Tumor-activated IL-2 mRNA delivered by lipid nanoparticles for cancer immunotherapy.
Efficient gene delivery by multifunctional star poly (β-amino ester)s into difficult-to-transfect macrophages for M1 polarization.
Investigating the role of itaconate in macrophage activation and oxidative stress injury in sepsis-associated acute kidney injury.
Autophagy-related IFNG is a prognostic and immunochemotherapeutic biomarker of COAD patients.
Antimicrobial peptide-modified AIE visual composite wound dressing for promoting rapid healing of infected wounds.
Sophoricoside attenuates autoimmune‑mediated liver injury through the regulation of oxidative stress and the NF‑κB signaling pathway.
Lidocaine ameliorates intestinal barrier dysfunction in irritable bowel syndrome by modulating corticotropin-releasing hormone receptor 2.
SMURF1 inhibits the Th17 and Th17.1 polarization and improves the Treg/Th17 imbalance in systemic lupus erythematosus through the ubiquitination of RORγt.
A novel PD-1/PD-L1 pathway molecular typing-related signature for predicting prognosis and the tumor microenvironment in breast cancer.
Combination of canagliflozin and puerarin alleviates the lipotoxicity to diabetic kidney in mice.
Long-Term Immunogenicity and In Vitro Prophylactic Protective Efficacy of M. tuberculosis Fusion Protein DR2 Combined with Liposomal Adjuvant DIMQ as a Boosting Vaccine for BCG.
CD4(+) T cells aggravate hemorrhagic brain injury.
Silk Fibroin-Based Hydrogel Microneedles Deliver α-MSH to Promote Melanosome Delivery for Vitiligo Treatment.
Pulsatilla chinensis saponins ameliorated murine depression by inhibiting intestinal inflammation mediated IDO1 overexpression and rebalancing tryptophan metabolism.
Histone deacetylases inhibitor chidamide synergizes with humanized PD1 antibody to enhance T-cell chemokine expression and augment Ifn-γ response in NK-T cell lymphoma.
Involvement of interferon gamma signaling in spinal trigeminal caudal subnucleus astrocyte in orofacial neuropathic pain in rats with infraorbital nerve injury.
Chimeric Newcastle Disease Virus Vectors Expressing Human IFN-γ Mediate Target Immune Responses and Enable Multifaceted Treatments.
Fingolimod (FTY720) Hinders Interferon-γ-Mediated Fibrotic Scar Formation and Facilitates Neurological Recovery After Spinal Cord Injury.
TRAF5 regulates intestinal mucosal Th1/Th17 cell immune responses via Runx1 in colitis mice.
IFNγ Transcribed by IRF1 in CD4+ Effector Memory T Cells Promotes Senescence-Associated Pulmonary Fibrosis.
The Mitigatory Effect of Shen-Qi Compound on the Diabetic Thoracic Aortic Complications through Inhibiting the Inflammatory Microenvironment by miR-223-3p/RBP-J/IRF8 Axis.
Minocycline Alleviates White Matter Injury following Intracerebral Hemorrhage by Regulating CD4(+) T Cell Differentiation via Notch1 Signaling Pathway.
PD-L1 Inhibits T Cell-Induced Cytokines and Hyaluronan Expression via the CD40-CD40L Pathway in Orbital Fibroblasts From Patients With Thyroid Associated Ophthalmopathy.
CXCL10-armed oncolytic adenovirus promotes tumor-infiltrating T-cell chemotaxis to enhance anti-PD-1 therapy.
A Composite Hydrogel Containing Mesoporous Silica Nanoparticles Loaded With Artemisia argyi Extract for Improving Chronic Wound Healing.
A bioactive dextran-based hydrogel promote the healing of infected wounds via antibacterial and immunomodulatory.
Protective effects of ZIP8 on Toxoplasma gondii-induced acute hepatocyte injury in mice.
LFA-1/ ICAM-1 promotes NK cell cytotoxicity associated with the pathogenesis of ocular toxoplasmosis in murine model.
An improved cell line-derived xenograft humanized mouse model for evaluation of PD-1/PD-L1 blocker BMS202-induced immune responses in colorectal cancer.
Aberrant hyperexpression of the RNA binding protein FMRP in tumors mediates immune evasion.
Polarization and β-Glucan Reprogram Immunomodulatory Metabolism in Human Macrophages and Ex Vivo in Human Lung Cancer Tissues.
Enhanced immunogenicity of the tuberculosis subunit Rv0572c vaccine delivered in DMT liposome adjuvant as a BCG-booster.
Exosomal circGSE1 promotes immune escape of hepatocellular carcinoma by inducing the expansion of regulatory T cells.
Human lung adenocarcinoma CD47 is upregulated by interferon-γ and promotes tumor metastasis.
Combinational Deletions of MGF360-9L and MGF505-7R Attenuated Highly Virulent African Swine Fever Virus and Conferred Protection against Homologous Challenge.
A Novel Rat Model of Dry Eye Induced by Aerosol Exposure of Particulate Matter.
Delivery of germacrone (GER) using macrophages-targeted polymeric nanoparticles and its application in rheumatoid arthritis.
Design, synthesis and evaluation of fused hybrids with acetylcholinesterase inhibiting and Nrf2 activating functions for Alzheimer's disease.
EGFR-phosphorylated GDH1 harmonizes with RSK2 to drive CREB activation and tumor metastasis in EGFR-activated lung cancer.
Augmented PFKFB3-mediated glycolysis by interferon-γ promotes inflammatory M1 polarization through the JAK2/STAT1 pathway in local vascular inflammation in Takayasu arteritis.
MEF2C promotes M1 macrophage polarization and Th1 responses.
Lactobacillus acidophilus ATCC 4356 Alleviates Renal Ischemia-Reperfusion Injury Through Antioxidant Stress and Anti-inflammatory Responses and Improves Intestinal Microbial Distribution.
Alterations in CD8(+) Tregs, CD56(+) Natural Killer Cells and IL-10 Are Associated With Invasiveness of Nonfunctioning Pituitary Adenomas (NFPAs).
Encapsulation of LXR ligand by D-Nap-GFFY hydrogel enhances anti-tumorigenic actions of LXR and removes LXR-induced lipogenesis.
The Role of Tim-3 on dNK Cells Dysfunction During Abnormal Pregnancy With Toxoplasma gondii Infection.
Self-assembled FeS-based cascade bioreactor with enhanced tumor penetration and synergistic treatments to trigger robust cancer immunotherapy.
Inhibition of NLRP3 inflammasome activation in myeloid-derived suppressor cells by andrographolide sulfonate contributes to 5-FU sensitization in mice.
Targeting regulator of G protein signaling 1 in tumor-specific T cells enhances their trafficking to breast cancer.
The role of IP-10 and its receptor CXCR3 in early pregnancy.
IL-27 Rα(+) cells promoted allorejection via enhancing STAT1/3/5 phosphorylation.
Apatinib enhanced anti-PD-1 therapy for colon cancer in mice via promoting PD-L1 expression.
Maladjustment of β-CGRP/α-CGRP Regulation of AQP5 Promotes Transition of Alveolar Epithelial Cell Apoptosis to Pulmonary Fibrosis.
Anti-inflammatory effects of α-MSH through p-CREB expression in sarcoidosis like granuloma model.
Total Glycosides of Peony Protects Against Inflammatory Bowel Disease by Regulating IL-23/IL-17 Axis and Th17/Treg Balance.
Dehydroepiandrosterone stimulates inflammation and impairs ovarian functions of polycystic ovary syndrome.
Low-Dose IFNγ Induces Tumor Cell Stemness in Tumor Microenvironment of Non-Small Cell Lung Cancer.
Macrophage polarization in human gingival tissue in response to periodontal disease.
Using IFN-γ antibodies to identify the pathogens of fungal rhinosinusitis: A novel immunohistochemical approach.
A comparison of CRISPR/Cas9 and siRNA-mediated ALDH2 gene silencing in human cell lines.
PD-1 axis expression in musculoskeletal tumors and antitumor effect of nivolumab in osteosarcoma model of humanized mouse.
Activation of liver X receptor plays a central role in antiviral actions of 25-hydroxycholesterol.
Xin-Jia-Xiang-Ru-Yin alleviated H1N1-induced acute lung injury and inhibited the IFN-γ-related regulatory pathway in summer flu.
Toll-Like Receptor 4-Myeloid Differentiation Primary Response Gene 88 Pathway Is Involved in the Inflammatory Development of Polymyositis by Mediating Interferon-γ and Interleukin-17A in Humans and Experimental Autoimmune Myositis Mouse Model.
Tumor PD-L1 expression is correlated with increased TILs and poor prognosis in penile squamous cell carcinoma.
The natural product fucoidan ameliorates hepatic ischemia-reperfusion injury in mice.
The liver protection of propylene glycol alginate sodium sulfate preconditioning against ischemia reperfusion injury: focusing MAPK pathway activity.
Orbital fibroblasts of Graves' orbitopathy stimulated with proinflammatory cytokines promote B cell survival by secreting BAFF.
Enteric dysbiosis-linked gut barrier disruption triggers early renal injury induced by chronic high salt feeding in mice.
Disruption of Tumor Necrosis Factor Receptor-Associated Factor 5 Exacerbates Murine Experimental Colitis via Regulating T Helper Cell-Mediated Inflammation.
MEK1/2 inhibitors induce interleukin-5 expression in mouse macrophages and lymphocytes.
Activation of liver X receptor inhibits the development of pulmonary carcinomas induced by 3-methylcholanthrene and butylated hydroxytoluene in BALB/c mice.
Effect of IL-17 in the development of colon cancer in mice.
A fundamental study on the dynamics of multiple biomarkers in mouse excisional wounds for wound age estimation.
Anti-inflammatory effect of topical administration of tofacitinib on corneal inflammation.
The quantum of initial transformed cells potentially modulates the type of local inflammation mechanism elicited by surrounding normal epithelial tissues and systemic immune pattern for tumor arrest or progression.
Inhibition of tumor growth by U0126 is associated with induction of interferon-γ production.
PTPROt maintains T cell immunity in the microenvironment of hepatocellular carcinoma.
Decreased percentages of regulatory T cells are necessary to activate Th1-Th17-Th22 responses during acute rejection of the peripheral nerve xenotransplantation in mice.
Echinococcus granulosus infection reduces airway inflammation of mice likely through enhancing IL-10 and down-regulation of IL-5 and IL-17A.
Identification of interferon-γ as a new molecular target of liver X receptor.
A novel role of IGFBP7 in mouse uterus: regulating uterine receptivity through Th1/Th2 lymphocyte balance and decidualization.
Interferon-γ-stimulated genes, but not USP18, are expressed in livers of patients with acute hepatitis C.
Implications of Th1 and Th17 cells in pathogenesis of oral lichen planus.
Li J, Zhou J, Zhang G, Ding N, Kuang Z, Wang J, Liu N, Jia G, Jiang M, Wu S, Yang J, Ding X, Lei Z, Nie Y, Zhang Y, Li Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158008
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158008
Potential effect and mechanism of ultrashort wave therapy in mice with chronic rhinosinusitis.
Xu H, Weng J, Bao Q, Jiang Y, Xiao C, Chen L
Biomedical reports 2026 Mar;24(3):36
Biomedical reports 2026 Mar;24(3):36
ITK-targeted immune remodeling enhanced the efficacy of anti-CD19 CAR-T cell therapy.
Li Z, Lv L, Yao X, Feng Z, Xie Y, Li K, Qi F, Yang M, Wang J, Pan T, Li X, Chen H, Wang J, Ding Y, Zhu J, Song Y, Wang X, Ding N
Cell death discovery 2026 Mar 6;12(1)
Cell death discovery 2026 Mar 6;12(1)
Capsular Polysaccharide of Lactiplantibacillus plantarum DPUL F232 Alleviates Whey Protein Allergy by Regulating Immunity, Gut Microbiota, and Production of SCFAs.
Feng L, Guo Z, Li X, Yao W, Mu G, Zhu X
Journal of agricultural and food chemistry 2026 Mar 11;74(9):7499-7515
Journal of agricultural and food chemistry 2026 Mar 11;74(9):7499-7515
Bie-Jia-Jian Pill: Inhibiting tumor glycolysis and promoting CD8(+) cell-mediated anti-tumor immunity by targeting HIF-1α-PI3K/AKT/mTOR and CCL20 in hepatocellular carcinoma.
Liu Y, Yang X, Qin M, Chen W, Liu C, Jiang W, Wang Y, Tan S, Sun H, Chen J, Sun H, He S
Journal of ethnopharmacology 2026 Jun 28;365:121554
Journal of ethnopharmacology 2026 Jun 28;365:121554
CD80-Mediated T-Cell Suppression by Cancer Stem-like Cells in Head and Neck Squamous Cell Carcinoma.
Xiao M, Qiu L, Gao Q, Li R, Wang J, Feng Y, Li X, Ge X
Cells 2026 Jan 30;15(3)
Cells 2026 Jan 30;15(3)
Caffeine inhibited the hyperoxia-induced A2AR-ERK/p38 MAPK-IL-8 pathway in type II alveolar epithelial cells to suppress NETs formation in bronchopulmonary dysplasia.
Wang X, Song Y, Yu L, Song K
Pediatric research 2026 Apr 29;
Pediatric research 2026 Apr 29;
Astrocytic BDNF Modulates Sensitivity to Stress-Induced Anxiety-Like Behaviors.
Li WP, Liu GY, Wang SY, Hu J, Ji WJ, Zhu JM, Chang QY, Li TY, Wei GR, Shang JQ, Li HZ, Peng FH, Zhao YY, Su XH, Xie W
Research (Washington, D.C.) 2025;8:0818
Research (Washington, D.C.) 2025;8:0818
Oncolytic adenovirus H101 enhances the anti-tumor effects of PD-1 blockade via CD47 downregulation in tumor cells.
Qiao C, Xu Y, He Y, Cai Z, Wang H
Oncology research 2025;33(5):1161-1172
Oncology research 2025;33(5):1161-1172
Ultrasound-Targeted Nanobubbles Codelivering NKP-1339 and miR-142-5p for Synergistic Mitochondrial Immunogenic Cell Death and PD-L1 Inhibition in Cancer Therapy.
Zhang Y, Liu C, Jin S, Xie L, Xiao Q, Yao J
Biomaterials research 2025;29:0232
Biomaterials research 2025;29:0232
Overexpression of Decorin Optimizes the Treatment Efficacy of Umbilical Cord Mesenchymal Stem Cells in Bleomycin-Induced Pulmonary Fibrosis in Rats.
Zhi Y, Shu M, Tang P, Li Y, Guo M, Deng J, Mo H, Wu M, Liu B, Mai Y, Ling J, Zhao X, Zhang X, Zuo W
Stem cells international 2025;2025:6324980
Stem cells international 2025;2025:6324980
Integrating cuproptosis- and ferroptosis-related gene signatures to predict prognosis, immunotherapy response, and drug sensitivity in patients with skin cutaneous melanoma.
Dong H, Huang Y, Shen J, Ding Z, Wang W, Li Y
Frontiers in immunology 2025;16:1742614
Frontiers in immunology 2025;16:1742614
Itraconazole inhibits the Wnt/β-catenin signaling pathway to induce tumor-associated macrophages polarization to enhance the efficacy of immunotherapy in endometrial cancer.
Guan X, Han L
Frontiers in oncology 2025;15:1590095
Frontiers in oncology 2025;15:1590095
Mature tertiary lymphoid structure associated CD103+ CD8+ Trm cells determined improved anti-tumor immune in breast cancer.
Fang Q, Chen S, Chen X, Zou W, Chen D, Huang Y, Wu C
Frontiers in oncology 2025;15:1480461
Frontiers in oncology 2025;15:1480461
Bacterial cellulose membrane integrating phase-transited lysozyme nanofilm loaded with biguanides for dressing treatment of atopic dermatitis.
Lin J, Yu H, Huang Y, Yuan J, Wang C, Bai B
International journal of biological macromolecules 2025 Sep;323(Pt 1):147047
International journal of biological macromolecules 2025 Sep;323(Pt 1):147047
Epigenetic suppression of Nrf2-Slc40a1 axis induces ferroptosis and enhances immunotherapy in pancreatic cancer.
Zhang Y, Yu R, Li Q, Song S, Fu Y, Shen X, Xu T, Zhang Y, Liang J, Zhang Z, Xu S, Tang J, Zhao Y, Shen C, Zhuang Y, Zhang J, Wang L, Zou X, Chen D, Lv Y, Zhang S
Journal for immunotherapy of cancer 2025 Oct 23;13(10)
Journal for immunotherapy of cancer 2025 Oct 23;13(10)
A STAT1-GBP3-STING positive feedback loop governs inflammation, oxidative stress, and DNA damage to trigger acute aortic dissection.
Bu SM, Wang WL, Liu YM, Li Q, Sun JY, Zhao XR, Miao XB, Zhao YB, Zhao YP, Song ZX, Ma D
Cellular signalling 2025 Nov;135:112015
Cellular signalling 2025 Nov;135:112015
Efferocytosis-related signatures identified via Single-cell analysis and machine learning predict TNBC outcomes and immunotherapy response.
Wei L, Wen S, Dang T, Zeng T, Yang S, You Y, Tang J, Sun H, Zhang L, Li Q, Li X, Sun M, He X, Zhao L, Zhu X, Zhang Y
Scientific reports 2025 Nov 6;15(1):38955
Scientific reports 2025 Nov 6;15(1):38955
A matrix stiffness gene signature identifies SLC20A1 as a novel mechano-immunological checkpoint enabling synergistic immunotherapy in pancreatic ductal adenocarcinoma.
Zhao C, Lu Y, He L, Zhang Y, Yin T
Cancer immunology, immunotherapy : CII 2025 Nov 12;74(12):367
Cancer immunology, immunotherapy : CII 2025 Nov 12;74(12):367
Analysis of differential transcriptome expression reveals that ISG15 provides support for embryo development by promoting angiogenesis in porcine mesometrium.
Gan J, Wang Y, Zhang F, Zang X, Meng F, Gu T, Xu Z, Li Z, Cai G, Wu Z, Hong L
International journal of biological macromolecules 2025 May;306(Pt 4):141601
International journal of biological macromolecules 2025 May;306(Pt 4):141601
Targeting KMT5C Suppresses Lung Cancer Progression and Enhances the Efficacy of Immunotherapy.
Yuan Y, Li Q, Yan G, Qian Y, Guo W, Li S, Wang F, Shang W, Zhu Z, Ge D, Wang Y, Liu Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(19):e2407575
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(19):e2407575
Drug-loaded microneedle patches containing regulatory T cell-derived exosomes for psoriasis treatment.
Ou M, Cao J, Luo R, Zhu B, Miao R, Yu L, Wang X, Li W, Fu Y, Zhang J, Zhang F, Wang Q, Mei L
Acta biomaterialia 2025 May 15;198:452-466
Acta biomaterialia 2025 May 15;198:452-466
Pectin/caffeic acid nanoparticles in a poloxamer thermosensitive gel for the treatment of ulcerative colitis by inhibiting cGAS-STING pathway.
Zhou S, Yu Z, Yao W, Wang M, Yang Y, Qin J, Wu X, Guo C
Colloids and surfaces. B, Biointerfaces 2025 Mar;247:114419
Colloids and surfaces. B, Biointerfaces 2025 Mar;247:114419
Chemotherapy boosts anti-angiogenic and anti-PD-1 combination therapy through activation of cCAS-STING pathway in colon cancer.
Li X, Dong Y, Wang T, Huang K, Guo W, Xu L, Gu Y
International immunopharmacology 2025 Mar 6;149:114212
International immunopharmacology 2025 Mar 6;149:114212
Sorafenib-loaded metal-organic framework nanoparticles for anti-hepatocellular carcinoma effects through synergistically potentiating ferroptosis and remodeling tumor immune microenvironment.
Yan Y, Hu J, Han N, Li HT, Yang X, Li LG, Xu Z, Xia F, Li J, Li TF, Chen R
Materials today. Bio 2025 Jun;32:101848
Materials today. Bio 2025 Jun;32:101848
Effect of COL11A1 on oral squamous cell carcinoma.
Liu YH, Li D, Zhang HL, Zhang BH, Song WJ, Li TK
Journal of stomatology, oral and maxillofacial surgery 2025 Jun;126(3S):102183
Journal of stomatology, oral and maxillofacial surgery 2025 Jun;126(3S):102183
Design, synthesis and bioevaluation of novel hydrazide derivatives as enhancers of immunotherapy and DNA-damage response in antitumor therapy.
Hu Z, Li S, Pan W, Wu H, Peng X
European journal of medicinal chemistry 2025 Jul 5;291:117601
European journal of medicinal chemistry 2025 Jul 5;291:117601
Causal genes identification of giant cell arteritis in CD4+ Memory t cells: an integration of multi-omics and expression quantitative trait locus analysis.
Yu Q, Wu Y, Ma X, Zhang Y
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2025 Jan 7;74(1):3
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2025 Jan 7;74(1):3
PD-L1 and IFN-γ modulate Non-Small Cell Lung Cancer (NSCLC) cell plasticity associated to immune checkpoint inhibitor (ICI)-mediated hyperprogressive disease (HPD).
Angelicola S, Giunchi F, Ruzzi F, Frascino M, Pitzalis M, Scalambra L, Semprini MS, Pittino OM, Cappello C, Siracusa I, Chillico IC, Di Noia M, Turato C, De Siervi S, Lescai F, Ciavattini T, Lopatriello G, Bertoli L, De Jonge H, Iamele L, Altimari A, Gruppioni E, Ardizzoni A, Rossato M, Gelsomino F, Lollini PL, Palladini A
Journal of translational medicine 2025 Jan 2;23(1):2
Journal of translational medicine 2025 Jan 2;23(1):2
Time-series single-cell transcriptomic profiling of luteal-phase endometrium uncovers dynamic characteristics and its dysregulation in recurrent implantation failures.
Cao D, Liu Y, Cheng Y, Wang J, Zhang B, Zhai Y, Zhu K, Liu Y, Shang Y, Xiao X, Chang Y, Lee YL, Yeung WSB, Huang Y, Yao Y
Nature communications 2025 Jan 2;16(1):137
Nature communications 2025 Jan 2;16(1):137
IFNγ regulates ferroptosis in KFs by inhibiting the expression of SPOCD1 through DNMT3A.
Wang X, Yang Y, Zhou X, Yu S, Luo X, Lu L, Gao Z, Yang J
Cell death discovery 2025 Jan 16;11(1):9
Cell death discovery 2025 Jan 16;11(1):9
Intra-cisterna-magna bevacizumab injection (ICM-BI) reproduces pathological alterations of cerebral small vessel diseases.
Kang X, Su X, Li T, Wang S, Huang H, Liu Y, Li C, Deng X, Hu M, Lu T, Wei L, Cai W, Lu Z
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2025 Feb;45(2):244-258
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2025 Feb;45(2):244-258
Molecular Subtyping and Therapeutic Targeting of IFNG-Driven Immunogenic Cell Death in Lung Adenocarcinoma.
Li L, Yang Y, Peng M, Wang B, Zhu L, Chen C, Fan Z, Duan X, Xue R, Lv X, Cheng M, Zhao J
Cancer medicine 2025 Feb;14(4):e70678
Cancer medicine 2025 Feb;14(4):e70678
Targeting Deltex E3 Ubiquitin Ligase 2 Inhibits Tumor-associated Neutrophils and Sensitizes Hepatocellular Carcinoma Cells to Immunotherapy.
Wu X, Chen J, Chen Y, Song S, Fang Y, Mao S, Gao J, Zhu G, Qu W, Zhao Q, Yang R, Guan Z, Chu T, Bu Y, Wang Y, Chen F, Zhou J, Fan J, Tang Z, Liu W, Ruan Y, Shi Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(7):e2408233
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(7):e2408233
LncRNA RNF144A-AS1 gene polymorphisms and their influence on lung cancer patients in the Chinese Han population.
Wu H, Xie Y, Li A, Liu X, Guo L, Wu F, Yang Z, Zhang Z, Zhang X
Non-coding RNA research 2025 Feb;10:252-260
Non-coding RNA research 2025 Feb;10:252-260
Reductive Adjuvant Nanosystem for Alleviated Atopic Dermatitis Syndromes.
Lu Y, Shan X, Huang J, Zhou H, Zhu Y, Wang S, Luo Z, Liu X, Guo X, Shi Y, Hu Y, Liu H, Zhang J, Huang P, Luo L, You J
ACS nano 2025 Feb 4;19(4):4195-4212
ACS nano 2025 Feb 4;19(4):4195-4212
IFN-γ-mediated inhibition of JAK/STAT signaling via nano-scutellarin treatment is an efficient strategy for ameliorating liver fibrosis.
Wang T, Liu B, Huang J, Zhao Q, Shen H, Bi T, Liu Z, Dai Y, Sun Q
Journal of translational medicine 2025 Feb 17;23(1):195
Journal of translational medicine 2025 Feb 17;23(1):195
Deletion of the African swine fever virus E120R gene completely attenuates its virulence by enhancing host innate immunity and impairing virus release.
Ma B, Jiang Y, Li N, Wang F, Li Q, Yue H, Zhang Y, Hu R, Miao F
Emerging microbes & infections 2025 Dec;14(1):2555722
Emerging microbes & infections 2025 Dec;14(1):2555722
Prognostic value of LPAR1 expression and methylation in low-grade gliomas: a meta-analysis of TCGA and CGGA datasets and functional validation.
Chen H, Liang W, Li Z, Bian C, Wang H, Luo S, Xin Y, Feng W, Liang L
BMC cancer 2025 Dec 30;26(1):161
BMC cancer 2025 Dec 30;26(1):161
Radiotherapy Combined with Immune Checkpoint Inhibitor on Murine Fibrosarcoma and a Narrative Review of Clinical Studies.
Kim W, Kim H, Jang WI, Kim MS, Bae SH
Current issues in molecular biology 2025 Dec 24;48(1)
Current issues in molecular biology 2025 Dec 24;48(1)
Gestational and Lactational Exposure to BPS Triggers Microglial Ferroptosis via the SLC7A11/GPX4 Antioxidant Axis and Induces Memory Impairment in Offspring Mice.
Xu N, Guo X, Su Y, Pan M, Lin K, Ma Z, Zhou H, Zeng H
International journal of molecular sciences 2025 Dec 11;26(24)
International journal of molecular sciences 2025 Dec 11;26(24)
Elevated Body Mass Index Aggravates Histopathological Changes and Postoperative Recurrence Risk in Nasal Polyps.
Jiang S, Liu L, Zhang H, Xie Z, Xie S, Jiang W
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 2025 Aug;173(2):522-533
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 2025 Aug;173(2):522-533
Abnormal miR-122-5p expression in decidual NK cells and its impact on trophoblast behavior: insights into unexplained recurrent pregnancy loss.
Liu Y, Li L, Feng T, Zhou W, Liu Y, Mu Y, He Z, Li H
International journal of medical sciences 2024;21(14):2824-2836
International journal of medical sciences 2024;21(14):2824-2836
Neoadjuvant immunochemotherapy improves clinical outcomes of patients with esophageal cancer by mediating anti-tumor immunity of CD8+ T (Tc1) and CD16+ NK cells.
He Y, Yang D, Lin X, Zhang J, Cheng R, Cao L, Yang L, Zhang M, Shi X, Jin X, Sun H, Sun H, Zang J, Li Y, Ma J, Nie H
Frontiers in immunology 2024;15:1412693
Frontiers in immunology 2024;15:1412693
Construction of disulfidptosis-based immune response prediction model with artificial intelligence and validation of the pivotal grouping oncogene c-MET in regulating T cell exhaustion.
Li P, Wang S, Wan H, Huang Y, Yin K, Sun K, Jin H, Wang Z
Frontiers in immunology 2024;15:1258475
Frontiers in immunology 2024;15:1258475
Mechanism of Lian Hua Qing Wen capsules regulates the inflammatory response caused by M(1) macrophage based on cellular experiments and computer simulations.
Zong YH, Cao JF, Zhao Y, Gao M, Chen WL, Wu M, Xu X, Xu ZY, Zhang XQ, Tang JZ, Liu Y, Hu XS, Wang SQ, Zhang X
Acta tropica 2024 Sep;257:107320
Acta tropica 2024 Sep;257:107320
Vimentin, inversely correlating with infiltration of CD8 + T lymphocytes, promotes nuclear translocation of PD-L1 in esophageal squamous cell carcinoma.
Liang Y, He S, Liu Q, Liu T, Tan Y, Peng T, Huang C, Lu X, Zheng S
Biochimica et biophysica acta. Molecular cell research 2024 Oct;1871(7):119781
Biochimica et biophysica acta. Molecular cell research 2024 Oct;1871(7):119781
Corynebacterium parakroppenstedtii secretes a novel glycolipid to promote the development of granulomatous lobular mastitis.
Liu R, Luo Z, Dai C, Wei Y, Yan S, Kuang X, Qi K, Fu A, Li Y, Fu S, Ma Z, Dai W, Xiao X, Wu Q, Zhou H, Rao Y, Yuan J, Shi T, Deng Z, Chen C, Liu T
Signal transduction and targeted therapy 2024 Oct 21;9(1):292
Signal transduction and targeted therapy 2024 Oct 21;9(1):292
Chaperonin-containing TCP1 subunit 6A inhibition via TRIM21-mediated K48-linked ubiquitination suppresses triple-negative breast cancer progression through the AKT signalling pathway.
Yang M, Cao J, Liu T, Li B, Wang J, Pan S, Guo D, Tao Z, Hu X
Clinical and translational medicine 2024 Nov;14(11):e70097
Clinical and translational medicine 2024 Nov;14(11):e70097
IFN-γ derived from activated human CD4(+) T cells inhibits the replication of SARS-CoV-2 depending on cell-type and viral strain.
Shimizu J, Sasaki T, Ong GH, Koketsu R, Samune Y, Nakayama EE, Nagamoto T, Yamamoto Y, Miyazaki K, Shioda T
Scientific reports 2024 Nov 4;14(1):26660
Scientific reports 2024 Nov 4;14(1):26660
Targeting AQP9 enhanced the anti-TNF therapy response in Crohn's disease by inhibiting LPA-hippo pathway.
Yu M, Shi Y, Gao Y, Luo Y, Jin Y, Liang X, Tao Z, Zhu G, Lin H, Li H, Qin J, Cao Z, Zhong M
Pharmacological research 2024 May;203:107172
Pharmacological research 2024 May;203:107172
Implications of IFNγ SNP rs2069705 in primary Sjögren's syndrome: transcriptional activation and B cell infiltration.
Chen X, Li M, Li H, Liu M, Su J, Ji Y
American journal of physiology. Cell physiology 2024 May 1;326(5):C1494-C1504
American journal of physiology. Cell physiology 2024 May 1;326(5):C1494-C1504
Transcutaneous Auricular Vagus Nerve Stimulation Alleviates Monobenzone-Induced Vitiligo in Mice.
Luo S, Meng X, Ai J, Zhang Z, Dai Y, Yu X
International journal of molecular sciences 2024 Mar 18;25(6)
International journal of molecular sciences 2024 Mar 18;25(6)
The construction of modular universal chimeric antigen receptor T (MU-CAR-T) cells by covalent linkage of allogeneic T cells and various antibody fragments.
Chen T, Deng J, Zhang Y, Liu B, Liu R, Zhu Y, Zhou M, Lin Y, Xia B, Lin K, Ma X, Zhang H
Molecular cancer 2024 Mar 11;23(1):53
Molecular cancer 2024 Mar 11;23(1):53
Pan-Cancer Single-Cell and Spatial-Resolved Profiling Reveals the Immunosuppressive Role of APOE+ Macrophages in Immune Checkpoint Inhibitor Therapy.
Liu C, Xie J, Lin B, Tian W, Wu Y, Xin S, Hong L, Li X, Liu L, Jin Y, Tang H, Deng X, Zou Y, Zheng S, Fang W, Cheng J, Dai X, Bao X, Zhao P
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jun;11(23):e2401061
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jun;11(23):e2401061
Interferon Gamma Induces Higher Neutrophil Extracellular Traps Leading to Tumor-Killing Activity in Microsatellite Stable Colorectal Cancer.
Teng HW, Wang TY, Lin CC, Tong ZJ, Cheng HW, Wang HT
Molecular cancer therapeutics 2024 Jul 2;23(7):1043-1056
Molecular cancer therapeutics 2024 Jul 2;23(7):1043-1056
Comprehensive molecular characterization of long-term glioblastoma survivors.
Xu H, Chen X, Sun Y, Hu X, Zhang X, Wang Y, Tang Q, Zhu Q, Song K, Chen H, Sheng X, Yao Y, Zhuang D, Chen L, Mao Y, Qin Z
Cancer letters 2024 Jul 1;593:216938
Cancer letters 2024 Jul 1;593:216938
Cell fusion upregulates PD-L1 expression for evasion from immunosurveillance.
Tajima Y, Shibasaki F, Masai H
Cancer gene therapy 2024 Jan;31(1):158-173
Cancer gene therapy 2024 Jan;31(1):158-173
An oncolytic system produces oxygen selectively in pancreatic tumor cells to alleviate hypoxia and improve immune activation.
Chen Y, Wang J, Huang Y, Wu J, Wang Y, Chen A, Guo Q, Zhang Y, Zhang S, Wang L, Zou X, Li X
Pharmacological research 2024 Jan;199:107053
Pharmacological research 2024 Jan;199:107053
Increased S. aureus colonization and reduced antimicrobial peptide expression in erythrodermic psoriasis.
Liu Y, Wu X, Song P, Liu L, Zhong X, He Q, Zhang Z
International immunopharmacology 2024 Jan 25;127:111343
International immunopharmacology 2024 Jan 25;127:111343
A High MCT-Based Ketogenic Diet Suppresses Th1 and Th17 Responses to Ameliorate Experimental Autoimmune Encephalomyelitis in Mice by Inhibiting GSDMD and JAK2-STAT3/4 Pathways.
Zhang Q, Sun W, Wang Q, Zheng X, Zhang R, Zhang N
Molecular nutrition & food research 2024 Feb;68(3):e2300602
Molecular nutrition & food research 2024 Feb;68(3):e2300602
The Identification of Gamma-Glutamyl Hydrolase in Uterine Corpus Endometrial Carcinoma: a Predictive Model and Machine Learning.
Zhu C, Du Y, Huai Q, Fang N, Xu W, Yang J, Li X, Zhang Y, Zhang X, Dai H, Li X, Wang H, Dai Y
Reproductive sciences (Thousand Oaks, Calif.) 2024 Feb;31(2):532-549
Reproductive sciences (Thousand Oaks, Calif.) 2024 Feb;31(2):532-549
Targeting CD38/ ADP-ribosyl cyclase as a novel therapeutic strategy for identification of three potent agonists for leukopenia treatment.
Liu Y, Zhang L, Wang L, Tang X, Wan S, Huang Q, Ran M, Shen H, Yang Y, Chiampanichayakul S, Tima S, Anuchapreeda S, Wu J
Pharmacological research 2024 Feb;200:107068
Pharmacological research 2024 Feb;200:107068
Blockade of C5a receptor unleashes tumor-associated macrophage antitumor response and enhances CXCL9-dependent CD8(+) T cell activity.
Luan X, Lei T, Fang J, Liu X, Fu H, Li Y, Chu W, Jiang P, Tong C, Qi H, Fu Y
Molecular therapy : the journal of the American Society of Gene Therapy 2024 Feb 7;32(2):469-489
Molecular therapy : the journal of the American Society of Gene Therapy 2024 Feb 7;32(2):469-489
ATP6AP1 as a potential prognostic biomarker in CRC by comprehensive analysis and verification.
Zhang S, Wang Y, Zhang X, Wang M, Wu H, Tao Y, Fan W, Liu L, Wang B, Gao W
Scientific reports 2024 Feb 18;14(1):4018
Scientific reports 2024 Feb 18;14(1):4018
L-lysine supplementation attenuates experimental autoimmune hepatitis in a chronic murine model.
Lei Y, Chen Y, Wang S, Lin Z, Han P, Tian D, Wang H, Liu M
Experimental animals 2024 Feb 14;73(1):83-92
Experimental animals 2024 Feb 14;73(1):83-92
STING Activation in Macrophages and Microglia Drives Poststroke Inflammation: Implications for Neuroinflammatory Mechanisms and Therapeutic Interventions.
Liu Z, Qin Q, Wang S, Kang X, Liu Y, Wei L, Lu Z, Cai W, Hu M
CNS neuroscience & therapeutics 2024 Dec;30(12):e70106
CNS neuroscience & therapeutics 2024 Dec;30(12):e70106
EVA1B facilitates esophageal squamous carcinoma progression and recruitment of immunosuppressive myeloid-derived suppressor cells in the tumor microenvironment.
Xia T, Zhang Y, Peng H, Jia X, Yang D, Wei L, Li T, Yao W
Pharmacological research 2024 Dec;210:107521
Pharmacological research 2024 Dec;210:107521
The plant extract PNS mitigates atherosclerosis via promoting Nrf2-mediated inhibition of ferroptosis through reducing USP2-mediated Keap1 deubiquitination.
Zhao Y, Zheng G, Yang S, Liu S, Wu Y, Miao Y, Liang Z, Hua Y, Zhang J, Shi J, Li D, Cheng Y, Zhang Y, Chen Y, Fan G, Ma C
British journal of pharmacology 2024 Dec;181(23):4822-4844
British journal of pharmacology 2024 Dec;181(23):4822-4844
NPSR1 promotes chronic colitis through regulating CD4(+) T cell effector function in inflammatory bowel disease.
Peng Y, Chen L, Chen X, Lin J, Wei J, Cheng J, Zhou F, Ge L, Zhou R, Ding F, Wang X
International immunopharmacology 2024 Dec 5;142(Pt B):113252
International immunopharmacology 2024 Dec 5;142(Pt B):113252
Anti-ulcerative colitis effect of rotating magnetic field on DSS-induced mice by modulating colonic inflammatory deterioration.
Yang H, Zhou C, Nie S, Xu S, Li M, Yu Q, Wei Y, Wang X
Molecular immunology 2024 Aug;172:23-37
Molecular immunology 2024 Aug;172:23-37
Exploring the mechanism of Lianhuaqingwen (LHQW) in treating chronic bronchitis based on network pharmacology and experimental validation.
Lin S, Wang S, Jiang Q, Liu S, Liu S, Cai T
Respiratory research 2024 Aug 2;25(1):294
Respiratory research 2024 Aug 2;25(1):294
Multi-regulatory potency of USP1 on inflammasome components promotes pyroptosis in thyroid follicular cells and contributes to the progression of Hashimoto's thyroiditis.
Zhao X, Ni W, Zheng W, Ni W, Sun C, Gu Y, Gu Z
Molecular medicine (Cambridge, Mass.) 2024 Aug 12;30(1):121
Molecular medicine (Cambridge, Mass.) 2024 Aug 12;30(1):121
Tumor-activated IL-2 mRNA delivered by lipid nanoparticles for cancer immunotherapy.
Jiang Y, Zhang Y, Liu C, Liu J, Xue W, Wang Z, Li X
Journal of controlled release : official journal of the Controlled Release Society 2024 Apr;368:663-675
Journal of controlled release : official journal of the Controlled Release Society 2024 Apr;368:663-675
Efficient gene delivery by multifunctional star poly (β-amino ester)s into difficult-to-transfect macrophages for M1 polarization.
Bo T, Wang C, Yao D, Jiang Q, Zhao Y, Wang F, He W, Xu W, Zhou H, Li M, Zhang S, Xue R
Journal of controlled release : official journal of the Controlled Release Society 2024 Apr;368:157-169
Journal of controlled release : official journal of the Controlled Release Society 2024 Apr;368:157-169
Investigating the role of itaconate in macrophage activation and oxidative stress injury in sepsis-associated acute kidney injury.
Yang L, Zhou P, Li R, Yin Y, Xie G, Shi L, Zhang P, Tao K
Molecular biology reports 2024 Apr 20;51(1):533
Molecular biology reports 2024 Apr 20;51(1):533
Autophagy-related IFNG is a prognostic and immunochemotherapeutic biomarker of COAD patients.
Yue T, Cai Y, Zhu J, Liu Y, Chen S, Wang P, Rong L
Frontiers in immunology 2023;14:1064704
Frontiers in immunology 2023;14:1064704
Antimicrobial peptide-modified AIE visual composite wound dressing for promoting rapid healing of infected wounds.
Chen Y, Qian H, Peng D, Jiang Y, Liu Q, Tan Y, Feng L, Cheng B, Li G
Frontiers in bioengineering and biotechnology 2023;11:1338172
Frontiers in bioengineering and biotechnology 2023;11:1338172
Sophoricoside attenuates autoimmune‑mediated liver injury through the regulation of oxidative stress and the NF‑κB signaling pathway.
Chen Y, Lei Y, Wang H, Wang L, Xu J, Wang S, Yu M, Peng Z, Xiao F, Tian D, Liu M
International journal of molecular medicine 2023 Sep;52(3)
International journal of molecular medicine 2023 Sep;52(3)
Lidocaine ameliorates intestinal barrier dysfunction in irritable bowel syndrome by modulating corticotropin-releasing hormone receptor 2.
Wang Y, Qiao M, Yao X, Feng Z, Hu R, Chen J, Liu L, Liu J, Sun Y, Guo Y
Neurogastroenterology and motility 2023 Nov;35(11):e14677
Neurogastroenterology and motility 2023 Nov;35(11):e14677
SMURF1 inhibits the Th17 and Th17.1 polarization and improves the Treg/Th17 imbalance in systemic lupus erythematosus through the ubiquitination of RORγt.
Zhong W, Feng L, Tian W, Qu H, Xu H, Ning K, Liu L, Liu W, Gong X, Chen H
Molecular immunology 2023 May;157:186-194
Molecular immunology 2023 May;157:186-194
A novel PD-1/PD-L1 pathway molecular typing-related signature for predicting prognosis and the tumor microenvironment in breast cancer.
Man Y, Dai C, Guo Q, Jiang L, Shi Y
Discover oncology 2023 May 8;14(1):59
Discover oncology 2023 May 8;14(1):59
Combination of canagliflozin and puerarin alleviates the lipotoxicity to diabetic kidney in mice.
Zhu Q, Zhou Q, Luo XL, Zhang XJ, Li SY
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2023 May 1;27(3):221-230
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2023 May 1;27(3):221-230
Long-Term Immunogenicity and In Vitro Prophylactic Protective Efficacy of M. tuberculosis Fusion Protein DR2 Combined with Liposomal Adjuvant DIMQ as a Boosting Vaccine for BCG.
Mao LR, Du JP, Wang XC, Xu LF, Zhang YP, Sun QS, Shi ZL, Xing YR, Su YX, Wang SJ, Wang J, Ma JL, Zhang JY
ACS infectious diseases 2023 Mar 10;9(3):593-608
ACS infectious diseases 2023 Mar 10;9(3):593-608
CD4(+) T cells aggravate hemorrhagic brain injury.
Shi SX, Xiu Y, Li Y, Yuan M, Shi K, Liu Q, Wang X, Jin WN
Science advances 2023 Jun 9;9(23):eabq0712
Science advances 2023 Jun 9;9(23):eabq0712
Silk Fibroin-Based Hydrogel Microneedles Deliver α-MSH to Promote Melanosome Delivery for Vitiligo Treatment.
Chong S, Wei C, Feng L, Guo R
ACS biomaterials science & engineering 2023 Jun 12;9(6):3368-3378
ACS biomaterials science & engineering 2023 Jun 12;9(6):3368-3378
Pulsatilla chinensis saponins ameliorated murine depression by inhibiting intestinal inflammation mediated IDO1 overexpression and rebalancing tryptophan metabolism.
Wang T, Song Y, Ai Z, Liu Y, Li H, Xu W, Chen L, Zhu G, Yang M, Su D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jul 25;116:154852
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jul 25;116:154852
Histone deacetylases inhibitor chidamide synergizes with humanized PD1 antibody to enhance T-cell chemokine expression and augment Ifn-γ response in NK-T cell lymphoma.
Wen T, Sun G, Jiang W, He X, Shi Y, Ma F, Liu P
EBioMedicine 2023 Jan;87:104420
EBioMedicine 2023 Jan;87:104420
Involvement of interferon gamma signaling in spinal trigeminal caudal subnucleus astrocyte in orofacial neuropathic pain in rats with infraorbital nerve injury.
Asano S, Okada-Ogawa A, Kobayashi M, Yonemoto M, Hojo Y, Shibuta I, Noma N, Iwata K, Hitomi S, Shinoda M
Molecular pain 2023 Jan-Dec;19:17448069231222403
Molecular pain 2023 Jan-Dec;19:17448069231222403
Chimeric Newcastle Disease Virus Vectors Expressing Human IFN-γ Mediate Target Immune Responses and Enable Multifaceted Treatments.
Soliman RM, Nishioka K, Daidoji T, Noyori O, Nakaya T
Biomedicines 2023 Feb 4;11(2)
Biomedicines 2023 Feb 4;11(2)
Fingolimod (FTY720) Hinders Interferon-γ-Mediated Fibrotic Scar Formation and Facilitates Neurological Recovery After Spinal Cord Injury.
Li Y, Chen Y, Hu X, Ouyang F, Li J, Huang J, Ye J, Shan F, Luo Y, Yu S, Li Z, Yao F, Liu Y, Shi Y, Zheng M, Cheng L, Jing J
Journal of neurotrauma 2023 Dec;40(23-24):2580-2595
Journal of neurotrauma 2023 Dec;40(23-24):2580-2595
TRAF5 regulates intestinal mucosal Th1/Th17 cell immune responses via Runx1 in colitis mice.
Li M, Gan C, Zhang R, Wang J, Wang Y, Zhu W, Liu L, Shang J, Zhao Q
Immunology 2023 Dec;170(4):495-509
Immunology 2023 Dec;170(4):495-509
IFNγ Transcribed by IRF1 in CD4+ Effector Memory T Cells Promotes Senescence-Associated Pulmonary Fibrosis.
Chen H, Wang Q, Li J, Li Y, Chen A, Zhou J, Zhao J, Mao Z, Zhou Z, Zhang J, Wang Y, Wang R, Li Q, Zhang Y, Jiang R, Miao D, Jin J
Aging and disease 2023 Dec 1;14(6):2215-2237
Aging and disease 2023 Dec 1;14(6):2215-2237
The Mitigatory Effect of Shen-Qi Compound on the Diabetic Thoracic Aortic Complications through Inhibiting the Inflammatory Microenvironment by miR-223-3p/RBP-J/IRF8 Axis.
Tian Y, Xu G, Gao H, Xie HY, Leng YL, Fu XX, Xie CG
Evidence-based complementary and alternative medicine : eCAM 2022;2022:6686931
Evidence-based complementary and alternative medicine : eCAM 2022;2022:6686931
Minocycline Alleviates White Matter Injury following Intracerebral Hemorrhage by Regulating CD4(+) T Cell Differentiation via Notch1 Signaling Pathway.
Yang H, Gao X, Xiao W, Su J, Li Y, Ni W, Gu Y
Oxidative medicine and cellular longevity 2022;2022:3435267
Oxidative medicine and cellular longevity 2022;2022:3435267
PD-L1 Inhibits T Cell-Induced Cytokines and Hyaluronan Expression via the CD40-CD40L Pathway in Orbital Fibroblasts From Patients With Thyroid Associated Ophthalmopathy.
Liu Z, Liu Y, Liu M, Gong Q, Shi A, Li X, Bai X, Guan X, Hao B, Liu F, Zhou X, Yuan H
Frontiers in immunology 2022;13:849480
Frontiers in immunology 2022;13:849480
CXCL10-armed oncolytic adenovirus promotes tumor-infiltrating T-cell chemotaxis to enhance anti-PD-1 therapy.
Li X, Lu M, Yuan M, Ye J, Zhang W, Xu L, Wu X, Hui B, Yang Y, Wei B, Guo C, Wei M, Dong J, Wu X, Gu Y
Oncoimmunology 2022;11(1):2118210
Oncoimmunology 2022;11(1):2118210
A Composite Hydrogel Containing Mesoporous Silica Nanoparticles Loaded With Artemisia argyi Extract for Improving Chronic Wound Healing.
Xue L, Deng T, Guo R, Peng L, Guo J, Tang F, Lin J, Jiang S, Lu H, Liu X, Deng L
Frontiers in bioengineering and biotechnology 2022;10:825339
Frontiers in bioengineering and biotechnology 2022;10:825339
A bioactive dextran-based hydrogel promote the healing of infected wounds via antibacterial and immunomodulatory.
Zhou L, Zhou L, Wei C, Guo R
Carbohydrate polymers 2022 Sep 1;291:119558
Carbohydrate polymers 2022 Sep 1;291:119558
Protective effects of ZIP8 on Toxoplasma gondii-induced acute hepatocyte injury in mice.
Wang Y, Wang C, Chen H, Zhang Y, Gao N, Yu Y, Xing Y, Xie L, Wang Z, Cai Y
Acta tropica 2022 Oct;234:106629
Acta tropica 2022 Oct;234:106629
LFA-1/ ICAM-1 promotes NK cell cytotoxicity associated with the pathogenesis of ocular toxoplasmosis in murine model.
Gao N, Wang C, Yu Y, Xie L, Xing Y, Zhang Y, Wang Y, Wu J, Cai Y
PLoS neglected tropical diseases 2022 Oct;16(10):e0010848
PLoS neglected tropical diseases 2022 Oct;16(10):e0010848
An improved cell line-derived xenograft humanized mouse model for evaluation of PD-1/PD-L1 blocker BMS202-induced immune responses in colorectal cancer.
Shang P, Yu L, Cao S, Guo C, Zhang W
Acta biochimica et biophysica Sinica 2022 Oct 25;54(10):1497-1506
Acta biochimica et biophysica Sinica 2022 Oct 25;54(10):1497-1506
Aberrant hyperexpression of the RNA binding protein FMRP in tumors mediates immune evasion.
Zeng Q, Saghafinia S, Chryplewicz A, Fournier N, Christe L, Xie YQ, Guillot J, Yucel S, Li P, Galván JA, Karamitopoulou E, Zlobec I, Ataca D, Gallean F, Zhang P, Rodriguez-Calero JA, Rubin M, Tichet M, Homicsko K, Hanahan D
Science (New York, N.Y.) 2022 Nov 18;378(6621):eabl7207
Science (New York, N.Y.) 2022 Nov 18;378(6621):eabl7207
Polarization and β-Glucan Reprogram Immunomodulatory Metabolism in Human Macrophages and Ex Vivo in Human Lung Cancer Tissues.
Fan TW, Daneshmandi S, Cassel TA, Uddin MB, Sledziona J, Thompson PT, Lin P, Higashi RM, Lane AN
Journal of immunology (Baltimore, Md. : 1950) 2022 Nov 1;209(9):1674-1690
Journal of immunology (Baltimore, Md. : 1950) 2022 Nov 1;209(9):1674-1690
Enhanced immunogenicity of the tuberculosis subunit Rv0572c vaccine delivered in DMT liposome adjuvant as a BCG-booster.
Mao L, Xu L, Wang X, Xing Y, Wang J, Zhang Y, Yuan W, Du J, Shi Z, Ma J, Zhang J, Zhang X, Wang X
Tuberculosis (Edinburgh, Scotland) 2022 May;134:102186
Tuberculosis (Edinburgh, Scotland) 2022 May;134:102186
Exosomal circGSE1 promotes immune escape of hepatocellular carcinoma by inducing the expansion of regulatory T cells.
Huang M, Huang X, Huang N
Cancer science 2022 Jun;113(6):1968-1983
Cancer science 2022 Jun;113(6):1968-1983
Human lung adenocarcinoma CD47 is upregulated by interferon-γ and promotes tumor metastasis.
Qu S, Jiao Z, Lu G, Xu J, Yao B, Wang T, Wang J, Yao Y, Yan X, Wang T, Liang H, Zen K
Molecular therapy oncolytics 2022 Jun 16;25:276-287
Molecular therapy oncolytics 2022 Jun 16;25:276-287
Combinational Deletions of MGF360-9L and MGF505-7R Attenuated Highly Virulent African Swine Fever Virus and Conferred Protection against Homologous Challenge.
Ding M, Dang W, Liu H, Xu F, Huang H, Sunkang Y, Li T, Pei J, Liu X, Zhang Y, Zheng H
Journal of virology 2022 Jul 27;96(14):e0032922
Journal of virology 2022 Jul 27;96(14):e0032922
A Novel Rat Model of Dry Eye Induced by Aerosol Exposure of Particulate Matter.
Mu N, Wang H, Chen D, Wang F, Ji L, Zhang C, Li M, Lu P
Investigative ophthalmology & visual science 2022 Jan 3;63(1):39
Investigative ophthalmology & visual science 2022 Jan 3;63(1):39
Delivery of germacrone (GER) using macrophages-targeted polymeric nanoparticles and its application in rheumatoid arthritis.
Tan T, Huang Q, Chu W, Li B, Wu J, Xia Q, Cao X
Drug delivery 2022 Dec;29(1):692-701
Drug delivery 2022 Dec;29(1):692-701
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European journal of medicinal chemistry 2022 Dec 15;244:114806
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Cell reports 2022 Dec 13;41(11):111827
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Arthritis research & therapy 2022 Dec 12;24(1):266
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Frontiers in nutrition 2021;8:667695
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Frontiers in cellular and infection microbiology 2021;11:587150
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- mouse thymus tissue were subjected to SDS PAGE followed by western blot with 15365-1-AP(IFNG antibody) at dilution of 1:800
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The interferon-gamma antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human interferon-gamma. This antibody recognizes human, mouse antigen. The interferon-gamma antibody has been validated for the following applications: ELISA, WB, IHC analysis.