MAB781-100

antibody from R&D Systems

Targeting: IFNG

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Antibody Data

Product number

MAB781-100

Provider

R&D Systems

Product name

Canine IFN-gamma Antibody

Antibody type

Monoclonal

Description

Protein A or G purified from hybridoma culture supernatant. Detects canine IFN-gamma in direct ELISAs and Western blots. In direct ELISAs, this antibody shows approximately 75% cross-reactivity with recombinant porcine IFN-gamma and no cross-reactivity with IFN-gamma from human, mouse, feline, rat, or rhesus macaque.

Reactivity

Canine

Host

Mouse

Conjugate

Unconjugated

Antigen sequence

P42161


Isotype

IgG

Antibody clone number

142529

Vial size

100 ug

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

References

Submitted references

Recovery of antigen-specific T cell responses from dogs infected with Leishmania (L.) infantum by use of vaccine associated TLR-agonist adjuvant.

Schaut RG, Grinnage-Pulley TL, Esch KJ, Toepp AJ, Duthie MS, Howard RF, Reed SG, Petersen CA
Vaccine 2016 Oct 17;34(44):5225-5234

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Recombinant Forms of Leishmania amazonensis Excreted/Secreted Promastigote Surface Antigen (PSA) Induce Protective Immune Responses in Dogs.

Petitdidier E, Pagniez J, Papierok G, Vincendeau P, Lemesre JL, Bras-Gonçalves R
PLoS neglected tropical diseases 2016 May;10(5):e0004614

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Programmed death 1-mediated T cell exhaustion during visceral leishmaniasis impairs phagocyte function.

Esch KJ, Juelsgaard R, Martinez PA, Jones DE, Petersen CA
Journal of immunology (Baltimore, Md. : 1950) 2013 Dec 1;191(11):5542-50

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Long-lasting protection against canine visceral leishmaniasis using the LiESAp-MDP vaccine in endemic areas of France: double-blind randomised efficacy field trial.

Lemesre JL, Holzmuller P, Gonçalves RB, Bourdoiseau G, Hugnet C, Cavaleyra M, Papierok G
Vaccine 2007 May 22;25(21):4223-34

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Vaccination with irradiated Ancylostoma caninum third stage larvae induces a Th2 protective response in dogs.

Fujiwara RT, Loukas A, Mendez S, Williamson AL, Bueno LL, Wang Y, Samuel A, Zhan B, Bottazzi ME, Hotez PJ, Bethony JM
Vaccine 2006 Jan 23;24(4):501-9

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Interleukin-12 augments a Th1-type immune response manifested as lymphocyte proliferation and interferon gamma production in Leishmania infantum-infected dogs.

Strauss-Ayali D, Baneth G, Shor S, Okano F, Jaffe CL
International journal for parasitology 2005 Jan;35(1):63-73

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Protection against experimental visceral leishmaniasis infection in dogs immunized with purified excreted secreted antigens of Leishmania infantum promastigotes.

Lemesre JL, Holzmuller P, Cavaleyra M, Gonçalves RB, Hottin G, Papierok G
Vaccine 2005 Apr 22;23(22):2825-40