502504

antibody from BioLegend

Targeting: IFNG

ELISA (Data presented on provider website)

Flow cytometry (Recommended by provider)

Other assay (Recommended by provider)

Antibody Data

Product number

502504

Provider

BioLegend

Proper citation

BioLegend Cat#502504, RRID:AB_315229

Product name

Biotin anti-human IFN-‹

Antibody type

Monoclonal

Antigen

Partially purified, native human IFN-γ

Description

Interferon-γ is a potent multifunctional cytokine which is secreted primarily by activated NK cells and T cells. Originally characterized based on anti-viral activities, IFN-γ also exerts anti-proliferative, immunoregulatory, and proinflammatory activities. IFN-γ can upregulate MHC class I and II antigen expression by antigen-presenting cells.

Reactivity

Human, Simian

Host

Mouse

Conjugate

Biotin

Isotype

IgG

Vial size

500 µg

Concentration

0.5 mg/ml

Storage

The antibody solution should be stored undiluted at 4°C. Do not freeze.

References

Submitted references

TNF-alpha drives human CD14+ monocytes to differentiate into CD70+ dendritic cells evoking Th1 and Th17 responses.

Iwamoto S, Iwai S, Tsujiyama K, Kurahashi C, Takeshita K, Naoe M, Masunaga A, Ogawa Y, Oguchi K, Miyazaki A
Journal of immunology (Baltimore, Md. : 1950) 2007 Aug 1;179(3):1449-57