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- Antibody Data
- Antigen structure
- References [2090]
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- Product number
- 3420-3-1000 - Provider product page
- Provider
- Mabtech
- Product name
- Anti-human IFN-g mAb (1-D1K), unconjugated
- Antibody type
- Monoclonal
- Description
- This monoclonal antibody enables specific detection of human IFN-g in immunoassays such as ELISpot, FluoroSpot, ELISA, and immunocytochemistry.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 1-D1K
- Vial size
- _1 mg
- Storage
- Store product at 4-8¡C or frozen at -20¡C or below. Avoid repeated freezing/thawing.
- Handling
- At least 18 months from date of receipt.
Submitted references Identification and validation of diagnostic cut-offs of the ELISpot assay for the diagnosis of invasive aspergillosis in high-risk patients.
Improved ELISPOT protocol for monitoring Th1/Th17 T-cell response following T.gondii infection.
Multiparameter immunoprofiling for the diagnosis and differentiation of progressive versus nonprogressive nontuberculous mycobacterial lung disease-A pilot study.
Distinct T cell responsiveness to different COVID-19 vaccines and cross-reactivity to SARS-CoV-2 variants with age and CMV status.
Keratinocyte-derived small extracellular vesicles supply antigens for CD1a-resticted T cells and promote their type 2 bias in the context of filaggrin insufficiency.
Assessing the immunogenicity risk of salmon calcitonin peptide impurities using in silico and in vitro methods.
Immune cell phenotype and function patterns across the life course in individuals from rural Uganda.
High frequencies of alpha common cold coronavirus/SARS-CoV-2 cross-reactive functional CD4(+) and CD8(+) memory T cells are associated with protection from symptomatic and fatal SARS-CoV-2 infections in unvaccinated COVID-19 patients.
A novel approach to designing viral precision vaccines applied to SARS-CoV-2.
Selective lysis of acute myeloid leukemia cells by CD34/CD3 bispecific antibody through the activation of γδ T-cells.
Arginase-1 specific CD8+ T cells react toward malignant and regulatory myeloid cells.
CD70 identifies alloreactive T cells and represents a potential target for prevention and treatment of acute GVHD.
Safety and Immunogenicity of a Messenger RNA-Based Cytomegalovirus Vaccine in Healthy Adults: Results From a Phase 1 Randomized Clinical Trial.
Interferon-γ Responses to Chlamydia trachomatis Vaccine Candidate Proteins in Women With Different Chlamydia Outcomes.
An in vitro CD8 T-cell priming assay enables epitope selection for hepatitis C virus vaccines.
Detection of virus-specific T cells via ELISpot corroborates early diagnosis in human Borna disease virus 1 (BoDV-1) encephalitis.
Photothermal Prussian blue nanoparticles generate potent multi-targeted tumor-specific T cells as an adoptive cell therapy.
Adaptive immune responses are larger and functionally preserved in a hypervaccinated individual.
Neoantigen-specific stimulation of tumor-infiltrating lymphocytes enables effective TCR isolation and expansion while preserving stem-like memory phenotypes.
Evaluation of naturally acquired immune responses against novel pre-erythrocytic Plasmodium vivax proteins in a low endemic malaria population located in the Peruvian Amazon Basin.
IL-10-producing regulatory cells impact on celiac disease evolution.
Humoral and T-cell response to SARS-CoV-2 mRNA vaccine in multiple sclerosis patients: Correlations with DMTs and clinical variables.
Boosting Vaccine Response in Autoimmune Rheumatic Disease Patients With Inadequate Seroconversion: An Analysis of the Immunogenicity of Vector-Based and Inactivated Vaccines.
Secretion of IFN-γ by specific T cells in HCMV infection.
Microfluidic Synthesis of Scalable Layer-by-Layer Multiple Antigen Nano-Delivery Platform for SARS-CoV-2 Vaccines.
Bivalent mRNA COVID vaccines elicit predominantly cross-reactive CD4(+) T cell clonotypes.
Neutralizing antibody titers against D8 genotype and persistence of measles humoral and cell-mediated immunity eight years after the first dose of measles, mumps, and rubella vaccine in Brazilian children.
Circular RNA as a source of neoantigens for cancer vaccines.
COVID-19 has no impact on disease activity, progression and cognitive performance in people with multiple sclerosis: a 2-year study.
HLA-class II restricted TCR targeting human papillomavirus type 18 E7 induces solid tumor remission in mice.
pH and ROS Responsiveness of Polymersome Nanovaccines for Antigen and Adjuvant Codelivery: An In Vitro and In Vivo Comparison.
Vaccination with Adenovirus Type 5 Vector-Based COVID-19 Vaccine as the Primary Series in Adults: A Randomized, Double-Blind, Placebo-Controlled Phase 1/2 Clinical Trial.
Cytotoxicity of fourth-generation anti-Trop2 CAR-T cells against breast cancer.
Impaired immune responses and prolonged viral replication in lung allograft recipients infected with SARS-CoV-2 in the early phase after transplantation.
MAIT cell-MR1 reactivity is highly conserved across multiple divergent species.
Electron transport chain capacity expands yellow fever vaccine immunogenicity.
A chimeric haemagglutinin-based universal influenza virus vaccine boosts human cellular immune responses directed towards the conserved haemagglutinin stalk domain and the viral nucleoprotein.
Identification of an HLA-A*11:01-restricted neoepitope of mutant PIK3CA and its specific T cell receptors for cancer immunotherapy targeting hotspot driver mutations.
Phase I Trial of Viral Vector-Based Personalized Vaccination Elicits Robust Neoantigen-Specific Antitumor T-Cell Responses.
Rejection resistant CD30.CAR-modified Epstein-Barr virus-specific T cells as an off-the-shelf platform for CD30(+) lymphoma.
Single-cell landscape of functionally cured chronic hepatitis B patients reveals activation of innate and altered CD4-CTL-driven adaptive immunity.
Cotargeting EBV lytic as well as latent cycle antigens increases T-cell potency against lymphoma.
Frequency of SARS-CoV-2 Infections among Healthcare Workers in Germany: 3-Year Follow-Up Study.
SARS-CoV-2-specific T-cell responses are induced in people living with human immunodeficiency virus after booster vaccination.
Humoral and Cellular Response Induced by Primary Series and Booster Doses of mRNA Coronavirus Disease 2019 Vaccine in Patients with Cardiovascular Disease: A Longitudinal Study.
Immunogenicity of the Monovalent Omicron XBB.1.5-Adapted BNT162b2 COVID-19 Vaccine in People Living with HIV (PLWH).
Immune responses and clinical outcomes after COVID-19 vaccination in patients with liver disease and liver transplant recipients.
Humoral SARS-CoV-2 Vaccine Responses in Patients With Giant Cell Arteritis and Polymyalgia Rheumatica: Decay After Primary Vaccination and Effects of the Booster.
N(1)-methylpseudouridylation of mRNA causes +1 ribosomal frameshifting.
Multiple SARS-CoV-2 immunizations of an unvaccinated population lead to complex immunity. A T cell reactivity study of blood donors in Antananarivo.
The spike-specific TCRβ repertoire shows distinct features in unvaccinated or vaccinated patients with SARS-CoV-2 infection.
Structural elucidation of novel pro-inflammatory polysaccharides from Daphne mezereum L.
Orthopoxvirus-Specific T-Cell Responses in Convalescent Mpox Patients.
A Mixture of T-Cell Epitope Peptides Derived from Human Respiratory Syncytial Virus F Protein Conferred Protection in DR1-TCR Tg Mice.
Infliximab aggregates produced in severe and mild elevated temperature stress conditions induce an extended specific CD4 T-cell response.
Immunogenicity and reactogenicity of modified vaccinia Ankara pre-exposure vaccination against mpox according to previous smallpox vaccine exposure and HIV infection: prospective cohort study.
IFN-γ decreases PD-1 in T lymphocytes from convalescent COVID-19 patients via the AKT/GSK3β signaling pathway.
H3K27M neoepitope vaccination in diffuse midline glioma induces B and T cell responses across diverse HLA loci of a recovered patient.
A Broad-Spectrum Multi-Antigen mRNA/LNP-Based Pan-Coronavirus Vaccine Induced Potent Cross-Protective Immunity Against Infection and Disease Caused by Highly Pathogenic and Heavily Spike-Mutated SARS-CoV-2 Variants of Concern in the Syrian Hamster Model.
Stimulating T cell responses against patient-derived breast cancer cells with neoantigen peptide-loaded peripheral blood mononuclear cells.
Effective and targeted latency reversal in CD4(+) T cells from individuals on long term combined antiretroviral therapy initiated during chronic HIV-1 infection.
Immunogenicity of BNT162b2 as a first booster after a ChAdOx1 primary series in a Thai geriatric population living with frailty.
Human effector CD8(+) T cells with an activated and exhausted-like phenotype control tumour growth in vivo in a humanized tumour model.
T cell activation markers CD38 and HLA-DR indicative of non-seroconversion in anti-CD20-treated patients with multiple sclerosis following SARS-CoV-2 mRNA vaccination.
Treponema pallidum Periplasmic and Membrane Proteins Are Recognized by Circulating and Skin CD4+ T Cells.
A First-in-Human Phase I Clinical Study with MVX-ONCO-1, a Personalized Active Immunotherapy, in Patients with Advanced Solid Tumors.
Immunogenicity and safety of BNT162b2 vaccination in adolescents with systemic lupus erythematosus.
A novel multicolor fluorescent spot assay for the functional assessment of chimeric antigen receptor (CAR) T-cell products.
The influence of neonatal BCG vaccination on in vitro cytokine responses to Plasmodium falciparum.
Construction of novel multi-epitope-based diagnostic biomarker HP16118P and its application in the differential diagnosis of Mycobacterium tuberculosis latent infection.
Loss of NEDD8 in cancer cells causes vulnerability to immune checkpoint blockade in triple-negative breast cancer.
Potential Role of Circulating PD-L1(+) Leukocytes as a Predictor of Response to Anti-PD-(L)1 Therapy in NSCLC Patients.
Germline homozygosity and allelic imbalance of HLA-I are common in esophagogastric adenocarcinoma and impair the repertoire of immunogenic peptides.
Higher and Sustained Cell-Mediated Immune Responses After 3 Doses of mRNA COVID-19 Vaccine in Patients With Inflammatory Bowel Disease on Anti-Tumor Necrosis Factor Therapy.
The effects of exercise training for eight weeks on immune cell characteristics among breast cancer survivors.
T-Helper 22 Cell Type Responses to Nickel in Contact Allergic Subjects Are Associated with T-Helper 1, T-Helper 2, and T-Helper 17 Cell Cytokine Profile Responses and Patch Test Reactivity.
Spatiotemporal commonality of the TCR repertoire in a T-cell memory murine model and in metastatic human colorectal cancer.
Early evaluation of the safety, reactogenicity, and immune response after a single dose of modified vaccinia Ankara-Bavaria Nordic vaccine against mpox in children: a national outbreak response.
Electrolyte imbalance causes suppression of NK and T cell effector function in malignant ascites.
Optimization of Peripheral Blood Mononuclear Cell Processing for Improved Clinical ELISpot Assay Performance.
Human CD34(+)-derived complete plasmacytoid and conventional dendritic cell vaccine effectively induces antigen-specific CD8(+) T cell and NK cell responses in vitro and in vivo.
Targeting nucleic acid sensors in tumor cells to reprogram biogenesis and RNA cargo of extracellular vesicles for T cell-mediated cancer immunotherapy.
Immunogenicity and reactogenicity of fractional, heterologous primary COVID-19 vaccination schedules with BNT162b2 boosters in 5-11-year-old Thai children: A multicenter, prospective, double-blind, randomized control trial.
Fully closed cell sorter for immune cell therapy manufacturing.
Using patient-derived tumor organoids from common epithelial cancers to analyze personalized T-cell responses to neoantigens.
A phase 1 trial of adoptive transfer of vaccine-primed autologous circulating T cells in ovarian cancer.
A H3K27M-targeted vaccine in adults with diffuse midline glioma.
Safety and efficacy of one and two booster doses of SARS-CoV-2 mRNA vaccines in kidney transplant recipients: A randomized clinical trial.
Metabolic interventions improve HBV envelope-specific T-cell responses in patients with chronic hepatitis B.
Comparison of media for a human peripheral blood mononuclear cell-based in vitro vaccine evaluation system.
CD4+ and CD8+ T cells and antibodies are associated with protection against Delta vaccine breakthrough infection: a nested case-control study within the PITCH study.
B cell phenotype and serum levels of interferons, BAFF, and APRIL in multisystem inflammatory syndrome in children associated with COVID-19 (MIS-C).
DNMT and HDAC inhibition induces immunogenic neoantigens from human endogenous retroviral element-derived transcripts.
NK Receptors Replace CD28 As the Dominant Source of Signal 2 for Cognate Recognition of Cancer Cells by TAA-specific Effector CD8(+) T Cells.
A measles virus-based vaccine induces robust chikungunya virus-specific CD4(+) T-cell responses in a phase II clinical trial.
Neoantigen Targetability in Progressive Advanced Melanoma.
Lymph node dendritic cells harbor inducible replication-competent HIV despite years of suppressive ART.
Post-vaccination SARS-Cov-2 T-cell receptor repertoires in patients with multiple sclerosis and related disorders.
Safety and Efficacy of a Third Dose of the BNT162b2 Vaccine in Liver-Transplanted and Healthy Adolescents.
Myeloperoxidase creates a permissive microenvironmental niche for the progression of multiple myeloma.
Autoreactive T cells targeting type II pneumocyte antigens in COVID-19 convalescent patients.
Epitope-dependent effect of long-term cART on maintenance and recovery of HIV-1-specific CD8(+) T cells.
Natural killer cell responses during SARS-CoV-2 infection and vaccination in people living with HIV-1.
TIGIT(+) NK cells in combination with specific gut microbiota features predict response to checkpoint inhibitor therapy in melanoma patients.
Convalescent Adaptive Immunity Is Highly Heterogenous after SARS-CoV-2 Infection.
Machine learning methods and harmonized datasets improve immunogenic neoantigen prediction.
Safety and immunogenicity of a modified COVID-19 mRNA vaccine, SW-BIC-213, as a heterologous booster in healthy adults: an open-labeled, two-centered and multi-arm randomised, phase 1 trial.
Altered cellular immune response to vaccination against SARS-CoV-2 in patients suffering from autoimmunity with B-cell depleting therapy.
TAP2 Drives HLA-B∗13:01‒Linked Dapsone Hypersensitivity Syndrome Tolerance and Reactivity.
A protective, single-visit TB vaccination regimen by co-administration of a subunit vaccine with BCG.
Cytolytic CD8(+) T cells infiltrate germinal centers to limit ongoing HIV replication in spontaneous controller lymph nodes.
The role of CD8+ T-cell clones in immune thrombocytopenia.
Characterization of Duffy Binding Protein II-specific CD4(+)T cell responses in Plasmodium vivax patients.
Avelumab in Men With Metastatic Castration-Resistant Prostate Cancer, Enriched for Patients Treated Previously With a Therapeutic Cancer Vaccine.
Estimation of Sensitization Status in Renal Transplant Recipients by Assessing Indirect Pathway CD4 + T Cell Response to Donor Cell-pulsed Dendritic Cell.
Exercise mobilizes diverse antigen specific T-cells and elevates neutralizing antibodies in humans with natural immunity to SARS CoV-2.
Immunological signature in human cases of monkeypox infection in 2022 outbreak: an observational study.
A whole blood intracellular cytokine assay optimised for field site studies demonstrates polyfunctionality of CD4+ T cells in acute scrub typhus.
Pre-existing TGF-β-specific T-cell immunity in patients with pancreatic cancer predicts survival after checkpoint inhibitors combined with radiotherapy.
A systems immunology study comparing innate and adaptive immune responses in adults to COVID-19 mRNA and adenovirus vectored vaccines.
Functional SARS-CoV-2 cross-reactive CD4(+) T cells established in early childhood decline with age.
Th2-skewed T cells correlate with B cell response to α-Gal and tick antigens in α-Gal syndrome.
Interferon-gamma FlowSpot assay for the measurement of the T-cell response to cytomegalovirus.
Design and generation of mRNAs encoding conserved regions of SARS-CoV-2 ORF1ab for T cell-mediated immune activation.
Skin IL-17A and IFN-γ Production Correlate with Disease Severity in Patients with Psoriasis and Streptococcal Infection.
Navoximod modulates local HSV-1 replication to reshape tumor immune microenvironment for enhanced immunotherapy via an injectable hydrogel.
GRT-R910: a self-amplifying mRNA SARS-CoV-2 vaccine boosts immunity for ≥6 months in previously-vaccinated older adults.
Neoantigen-specific CD8 T cells with high structural avidity preferentially reside in and eliminate tumors.
Evaluation of QuantiFERON SARS-CoV-2 interferon-γ release assay following SARS-CoV-2 infection and vaccination.
Immunological imprinting of humoral immunity to SARS-CoV-2 in children.
GRAd-COV2 vaccine provides potent and durable humoral and cellular immunity to SARS-CoV-2 in randomized placebo-controlled phase 2 trial.
Immunogenicity and safety of heterologous immunisation with Ad5-nCOV in healthy adults aged 60 years and older primed with an inactivated SARS-CoV-2 vaccine (CoronaVac): a phase 4, randomised, observer-blind, non-inferiority trial.
Low levels of neutralizing antibodies against XBB Omicron subvariants after BA.5 infection.
A pilot study of lymphodepletion intensity for peripheral blood mononuclear cell-derived neoantigen-specific CD8 + T cell therapy in patients with advanced solid tumors.
SARS-CoV-2-specific immune responses and clinical outcomes after COVID-19 vaccination in patients with immune-suppressive disease.
Engineered tumor-specific T cells using immunostimulatory photothermal nanoparticles.
Specific immune response to mRNA vaccines against COVID-19 in patients receiving allogeneic stem cell transplantation for myeloid malignancy was altered by immunosuppressive therapy.
Short Carbon Nanotube-Based Delivery of mRNA for HIV-1 Vaccines.
Immunity of Heterologously and Homologously Boosted or Convalescent Individuals Against Omicron BA.1, BA.2, and BA.4/5 Variants.
Chronic Obstructive Pulmonary Disease and Cigarette Smoke Lead to Dysregulated Mucosal-associated Invariant T-Cell Activation.
γδ T cells are effectors of immunotherapy in cancers with HLA class I defects.
Potent high-avidity neutralizing antibodies and T cell responses after COVID-19 vaccination in individuals with B cell lymphoma and multiple myeloma.
Strong peak immunogenicity but rapid antibody waning following third vaccine dose in older residents of care homes.
Beta-lactam hypersensitivity diagnosis in ambulatory and hospitalized settings require different approaches.
Seroconversion rates in kidney transplant recipients following SARS-CoV-2 vaccination and its association with immunosuppressive agents: a systematic review and meta-analysis.
COVID-19 Severity, Cardiological Outcome, and Immunogenicity of mRNA Vaccine on Adult Patients With 22q11.2 DS.
Age-related Differences in Immune Reactions to SARS-CoV-2 Spike and Nucleocapsid Antigens.
Activated T cell therapy targeting glioblastoma cancer stem cells.
Tumor cells fail to present MHC-II-restricted epitopes derived from oncogenes to CD4+ T cells.
Attenuated humoral responses in HIV after SARS-CoV-2 vaccination linked to B cell defects and altered immune profiles.
A multidisciplinary approach to verify and de-label of drug allergic histories in a university hospital in Thailand: a retrospective descriptive study.
Definition and Characterization of SOX11-Derived T Cell Epitopes towards Immunotherapy of Glioma.
Improved predictions of antigen presentation and TCR recognition with MixMHCpred2.2 and PRIME2.0 reveal potent SARS-CoV-2 CD8(+) T-cell epitopes.
IFN-γ-Based ELISpot as a New Tool to Detect Human Infections with Borna Disease Virus 1 (BoDV-1): A Pilot Study.
T-cell responses induced by ChAdOx1 nCoV-19 (AZD1222) vaccine to wild-type severe acute respiratory syndrome coronavirus 2 among people with and without HIV in South Africa.
Preclinical development of a vaccine-based immunotherapy regimen (VBIR) that induces potent and durable T cell responses to tumor-associated self-antigens.
Long-lasting T-cell response to SARS-CoV-2 antigens after vaccination-a prospective cohort study of HCWs working with COVID-19 patients.
Effective personalized neoantigen vaccine plus anti-PD-1 in a PD-1 blockade-resistant lung cancer patient.
SARS-CoV-2-specific T cell and humoral immunity in individuals with and without HIV in an African population: a prospective cohort study.
CD103 and CD39 coexpression identifies neoantigen-specific cytotoxic T cells in colorectal cancers with low mutation burden.
Aminobisphosphonates reactivate the latent reservoir in people living with HIV-1.
Identification of T Cell Receptors Targeting a Neoantigen Derived from Recurrently Mutated FGFR3.
Definition of a New HLA B*52-Restricted Rev CTL Epitope Targeted by an HIV-1-Infected Controller.
Cohort-Specific Peptide Reagents Broaden Depth and Breadth Estimates of the CD8 T Cell Response to HIV-1 Gag Potential T Cell Epitopes.
Serum Neutralization Against SARS-CoV-2 Variants Is Heterogenic and Depends on Vaccination Regimen.
Hsp70, in Combination with IL-15 and PD-1 Blocker, Interferes with The Induction of Cytotoxic NK Cells in Relapsed Acute Myeloid Leukemia Patients.
The Negative Effect of Preexisting Immunity on Influenza Vaccine Responses Transcends the Impact of Vaccine Formulation Type and Vaccination History.
HPV-associated head and neck cancer is characterized by distinct profiles of CD8(+) T cells and myeloid-derived suppressor cells.
ATOR-1017 (evunzekibart), an Fc-gamma receptor conditional 4-1BB agonist designed for optimal safety and efficacy, activates exhausted T cells in combination with anti-PD-1.
Safety, efficacy, and immunogenicity of a replication-defective human cytomegalovirus vaccine, V160, in cytomegalovirus-seronegative women: a double-blind, randomised, placebo-controlled, phase 2b trial.
Immunogenicity, safety, and preliminary efficacy evaluation of OVX836, a nucleoprotein-based universal influenza A vaccine candidate: a randomised, double-blind, placebo-controlled, phase 2a trial.
TScan-II: A genome-scale platform for the de novo identification of CD4(+) T cell epitopes.
Impaired long-term anti-HBs responses in choronic hepatitis C patients: Results from a five-year follow-up study with healthy control.
Personalized neoantigen-based T cell therapy triggers cytotoxic lymphocytes expressing polyclonal TCR against metastatic ovarian cancer.
Investigating the Immune Basis of Green Tea Extract Induced Liver Injury in Healthy Donors Expressing HLA-B*35:01.
HBHA-IGRA and cytotoxic mediators release assays for the diagnosis of cervical tuberculous lymphadenitis.
Humoral and T cell responses to SARS-CoV-2 reveal insights into immunity during the early pandemic period in Pakistan.
Intradermal skin test with mRNA vaccines as a surrogate marker of T cell immunity in immunocompromised patients.
Effect of wash media type during PBMC isolation on downstream characterization of SARS-CoV-2-specific T cells.
Impact of delayed PBMC processing on functional and genomic assays.
Lenalidomide overcomes the resistance to third-generation CD19-CAR-T cell therapy in preclinical models of diffuse large B-cell lymphoma.
Validation of Multi-epitope Peptides Encapsulated in PLGA Nanoparticles Against Influenza A Virus.
SARS-CoV-2-specific T cell therapy for severe COVID-19: a randomized phase 1/2 trial.
Multifunctional IgG/IgM antibodies and cellular cytotoxicity are elicited by the full-length MSP1 SumayaVac-1 malaria vaccine.
Structural definition of HLA class II-presented SARS-CoV-2 epitopes reveals a mechanism to escape pre-existing CD4(+) T cell immunity.
Persistent symptoms after COVID-19 are not associated with differential SARS-CoV-2 antibody or T cell immunity.
Omicron infection following vaccination enhances a broad spectrum of immune responses dependent on infection history.
Proteogenomic analysis reveals RNA as a source for tumor-agnostic neoantigen identification.
Phase III Pivotal comparative clinical trial of intranasal (iNCOVACC) and intramuscular COVID 19 vaccine (Covaxin(®)).
Phase 1 clinical trial to assess safety and efficacy of NY-ESO-1-specific TCR T cells in HLA-A∗02:01 patients with advanced soft tissue sarcoma.
Complementarity-determining region clustering may cause CAR-T cell dysfunction.
Higher Cell-Mediated Immune Responses in Patients With Inflammatory Bowel Disease on Anti-TNF Therapy After COVID-19 Vaccination.
Validation of the performance and suitability of a new class of FBS optimized for use in single-cell functional assays.
Exhausted intratumoral Vδ2(-) γδ T cells in human kidney cancer retain effector function.
Third dose of COVID-19 mRNA vaccine closes the gap in immune response between naïve nursing home residents and healthy adults.
PP19128R, a Multiepitope Vaccine Designed to Prevent Latent Tuberculosis Infection, Induced Immune Responses In Silico and In Vitro Assays.
Case report: Treatment of long COVID with a SARS-CoV-2 antiviral and IL-6 blockade in a patient with rheumatoid arthritis and SARS-CoV-2 antigen persistence.
Safety and immunogenicity of a reduced dose of the BNT162b2 mRNA COVID-19 vaccine (REDU-VAC): A single blind, randomized, non-inferiority trial.
A phase 1b open-label dose-finding study of ustekinumab in young adults with type 1 diabetes.
Early SARS-CoV-2 dynamics and immune responses in unvaccinated participants of an intensely sampled longitudinal surveillance study.
Durable T-cellular and humoral responses in SARS-CoV-2 hospitalized and community patients.
Harmonization and qualification of an IFN-γ Enzyme-Linked ImmunoSpot assay (ELISPOT) to measure influenza-specific cell-mediated immunity within the FLUCOP consortium.
T cell perturbations persist for at least 6 months following hospitalization for COVID-19.
Brief Research Report: Anti-SARS-CoV-2 Immunity in Long Lasting Responders to Cancer Immunotherapy Through mRNA-Based COVID-19 Vaccination.
CoVITEST: A Fast and Reliable Method to Monitor Anti-SARS-CoV-2 Specific T Cells From Whole Blood.
Children and Adults With Mild COVID-19: Dynamics of the Memory T Cell Response up to 10 Months.
Evaluation of radio-immunotherapy sequence on immunological responses and clinical outcomes in patients with melanoma brain metastases (ELEKTRA).
Identification of Claudin 6-specific HLA class I- and HLA class II-restricted T cell receptors for cellular immunotherapy in ovarian cancer.
Transcriptional and functional analyses of neoantigen-specific CD4 T cells during a profound response to anti-PD-L1 in metastatic Merkel cell carcinoma.
Interferon-γ induces immunosuppression in salivary adenoid cystic carcinoma by regulating programmed death ligand 1 secretion.
Safety and immune response kinetics of GRAd-COV2 vaccine: phase 1 clinical trial results.
Accumulation of mutations in antibody and CD8 T cell epitopes in a B cell depleted lymphoma patient with chronic SARS-CoV-2 infection.
A randomized controlled trial of heterologous ChAdOx1 nCoV-19 and recombinant subunit vaccine MVC-COV1901 against COVID-19.
Immunodeficiency syndromes differentially impact the functional profile of SARS-CoV-2-specific T cells elicited by mRNA vaccination.
Effectiveness of Booster Doses of the SARS-CoV-2 Inactivated Vaccine KCONVAC against the Mutant Strains.
Anti-SARS-CoV-2 T-stem cell memory persists in ocrelizumab-treated MS patients.
Safety and immunogenicity of VPM1002 versus BCG in South African newborn babies: a randomised, phase 2 non-inferiority double-blind controlled trial.
De novo construction of T cell compartment in humanized mice engrafted with iPSC-derived thymus organoids.
Arginase-2-specific cytotoxic T cells specifically recognize functional regulatory T cells.
Administration of broadly neutralizing anti-HIV-1 antibodies at ART initiation maintains long-term CD8(+) T cell immunity.
A phase I study of an adenoviral vector delivering a MUC1/CD40-ligand fusion protein in patients with advanced adenocarcinoma.
The primordial differentiation of tumor-specific memory CD8(+) T cells as bona fide responders to PD-1/PD-L1 blockade in draining lymph nodes.
The oncogenic fusion protein DNAJB1-PRKACA can be specifically targeted by peptide-based immunotherapy in fibrolamellar hepatocellular carcinoma.
Quiescent innate and adaptive immune responses maintain the long-term integrity of corneal endothelium reconstituted through allogeneic cell injection therapy.
CD4 T cell epitope abundance in ferritin core potentiates responses to hemagglutinin nanoparticle vaccines.
Evolution of inflammation and immunity in a dengue virus 1 human infection model.
Epstein Barr virus-mediated transformation of B cells from XIAP-deficient patients leads to increased expression of the tumor suppressor CADM1.
Development of an Interferon-Gamma Release Assay (IGRA) to Aid Diagnosis of Histoplasmosis.
Immune Response after the Fourth Dose of SARS-CoV-2 mRNA Vaccine Compared to Natural Infection in Three Doses' Vaccinated Solid Organ Transplant Recipients.
Modification of the HLA-A*24:02 Peptide Binding Pocket Enhances Cognate Peptide-Binding Capacity and Antigen-Specific T Cell Activation.
Control of HIV-1 Replication by CD8(+) T Cells Specific for Two Novel Pol Protective Epitopes in HIV-1 Subtype A/E Infection.
S100A8-mediated metabolic adaptation controls HIV-1 persistence in macrophages in vivo.
Peroxynitrite in the tumor microenvironment changes the profile of antigens allowing escape from cancer immunotherapy.
Humoral and Cellular Immune Responses After a 3-dose Course of mRNA-1273 COVID-19 Vaccine in Kidney Transplant Recipients: A Prospective Cohort Study.
SARS-CoV-2 Spike-specific IFN-γ T-cell Response After COVID-19 Vaccination in Patients With Chronic Kidney Disease, on Dialysis, or Living With a Kidney Transplant.
Comparison of the rapidity of SARS-CoV-2 immune responses between primary and booster vaccination for COVID-19.
Immunogenicity and safety of two doses of SARS-CoV-2 mRNA vaccine in kidney transplant recipients with low-dose rituximab.
Differential immune transcriptomic profiles between vaccinated and resolved HCV reinfected subjects.
IFN-γ ELISpot in Severe Cutaneous Adverse Reactions to First-Line Antituberculosis Drugs in an HIV Endemic Setting.
Shared Clavulanate and Tazobactam Antigenic Determinants Activate T-Cells from Hypersensitive Patients.
Synthetic selenium nanoparticles as co-adjuvant improved immune responses against methicillin-resistant Staphylococcus aureus.
Kinetics of immune responses elicited after three mRNA COVID-19 vaccine doses in predominantly antibody-deficient individuals.
A comparative characterization of SARS-CoV-2-specific T cells induced by mRNA or inactive virus COVID-19 vaccines.
Additional heterologous versus homologous booster vaccination in immunosuppressed patients without SARS-CoV-2 antibody seroconversion after primary mRNA vaccination: a randomised controlled trial.
Elevated CD21(low) B Cell Frequency Is a Marker of Poor Immunity to Pfizer-BioNTech BNT162b2 mRNA Vaccine Against SARS-CoV-2 in Patients with Common Variable Immunodeficiency.
Sensitive identification of neoantigens and cognate TCRs in human solid tumors.
Immune responses against SARS-CoV-2 variants after two and three doses of vaccine in B-cell malignancies: UK PROSECO study.
Anti-SARS-CoV-2 vaccines in recipient and/or donor before allotransplant.
Safety and immunogenicity of heterologous boost immunization with an adenovirus type-5-vectored and protein-subunit-based COVID-19 vaccine (Convidecia/ZF2001): A randomized, observer-blinded, placebo-controlled trial.
A phenotypic signature that identifies neoantigen-reactive T cells in fresh human lung cancers.
Systemic Cancer Therapy Does Not Significantly Impact Early Vaccine-Elicited SARS-CoV-2 Immunity in Patients with Solid Tumors.
Competent immune responses to SARS-CoV-2 variants in older adults following two doses of mRNA vaccination.
Immunogenicity and safety of an intradermal ChAdOx1 nCoV-19 boost in a healthy population.
Functional in-vitro evaluation of the non-specific effects of BCG vaccination in a randomised controlled clinical study.
Vaccines elicit highly conserved cellular immunity to SARS-CoV-2 Omicron.
Phospholipase activity of acyloxyacyl hydrolase induces IL-22-producing CD1a-autoreactive T cells in individuals with psoriasis.
Reverted exhaustion phenotype of circulating lymphocytes as immune correlate of anti-PD1 first-line treatment in Hodgkin lymphoma.
Activation of human γδ T cells and NK cells by Staphylococcal enterotoxins requires both monocytes and conventional T cells.
Enhanced antigen cross-presentation in human colorectal cancer-associated fibroblasts through upregulation of the lysosomal protease cathepsin S.
Development of a T cell-based immunodiagnostic system to effectively distinguish SARS-CoV-2 infection and COVID-19 vaccination status.
Enhancement of Antiviral T-Cell Responses by Vitamin C Suggests New Strategies to Improve Manufacturing of Virus-Specific T Cells for Adoptive Immunotherapy.
Immunoescape of HIV-1 in Env-EL9 CD8 + T cell response restricted by HLA-B*14:02 in a Non progressor who lost twenty-seven years of HIV-1 control.
T cell reactivity to the SARS-CoV-2 Omicron variant is preserved in most but not all individuals.
Differential T cell immune responses to deamidated adeno-associated virus vector.
Divergent trajectories of antiviral memory after SARS-CoV-2 infection.
Antibody-Peptide Epitope Conjugates for Personalized Cancer Therapy.
Robust SARS-CoV-2-specific and heterologous immune responses in vaccine-naïve residents of long-term care facilities who survive natural infection.
Persistence of immune responses to the Sinopharm/BBIBP-CorV vaccine.
Targeting of Nrf2 improves antitumoral responses by human NK cells, TIL and CAR T cells during oxidative stress.
T Cell Immunogenicity, Gene Expression Profile, and Safety of Four Heterologous Prime-Boost Combinations of HIV Vaccine Candidates in Healthy Volunteers: Results of the Randomized Multi-Arm Phase I/II ANRS VRI01 Trial.
PD-1 and ICOS coexpression identifies tumor-reactive CD4+ T cells in human solid tumors.
Phase II Trial of Sipuleucel-T and Stereotactic Ablative Body Radiation for Patients with Metastatic Castrate-Resistant Prostate Cancer.
Cutting Edge: T Cell Responses to B.1.1.529 (Omicron) SARS-CoV-2 Variant Induced by COVID-19 Infection and/or mRNA Vaccination Are Largely Preserved.
CAR T cells expressing a bacterial virulence factor trigger potent bystander antitumour responses in solid cancers.
Contribution of pre-existing neoantigen-specific T cells to a durable complete response after tumor-pulsed dendritic cell vaccine plus nivolumab therapy in a patient with metastatic salivary duct carcinoma.
Identification of shared neoantigens in esophageal carcinoma by the combination of comprehensive analysis of genomic data and in silico neoantigen prediction.
Antibody and cellular immune responses following dual COVID-19 vaccination within infection-naive residents of long-term care facilities: an observational cohort study.
Safety and immunogenicity of anti-SARS CoV-2 vaccine SOBERANA 02 in homologous or heterologous scheme: Open label phase I and phase IIa clinical trials.
Immunopotentiation by linking Hsp70 T-cell epitopes to Gag-Pol-Env-Nef-Rev multiepitope construct and increased IFN-gamma secretion in infected lymphocytes.
Comparison of two T-cell assays to evaluate T-cell responses to SARS-CoV-2 following vaccination in naïve and convalescent healthcare workers.
Local delivery of low-dose anti-CTLA-4 to the melanoma lymphatic basin leads to systemic T(reg) reduction and effector T cell activation.
Persistence of immunity and impact of third dose of inactivated COVID-19 vaccine against emerging variants.
Immunogenicity and Reactogenicity of Ad26.COV2.S in Korean Adults: A Prospective Cohort Study.
A COVID-19 peptide vaccine for the induction of SARS-CoV-2 T cell immunity.
Pre-existing polymerase-specific T cells expand in abortive seronegative SARS-CoV-2.
T-cell and antibody responses to first BNT162b2 vaccine dose in previously infected and SARS-CoV-2-naive UK health-care workers: a multicentre prospective cohort study.
Children develop robust and sustained cross-reactive spike-specific immune responses to SARS-CoV-2 infection.
CD161 expression and regulation defines rapidly responding effector CD4+ T cells associated with improved survival in HPV16-associated tumors.
Gut commensal Limosilactobacillus reuteri induces atypical memory-like phenotype in human dendritic cells in vitro.
Towards large-scale identification of HLA-restricted T cell epitopes from four vaccine candidate antigens in a malaria endemic community in Ghana.
Vaccines Elicit Highly Cross-Reactive Cellular Immunity to the SARS-CoV-2 Omicron Variant.
Two Distinct Mechanisms Leading to Loss of Virological Control in the Rare Group of Antiretroviral Therapy-Naive, Transiently Aviremic Children Living with HIV.
T-cells of invasive candidiasis patients show patterns of T-cell-exhaustion suggesting checkpoint blockade as treatment option.
Primary immune responses are negatively impacted by persistent herpesvirus infections in older people: results from an observational study on healthy subjects and a vaccination trial on subjects aged more than 70 years old.
SARS-CoV-2 specific cellular response following COVID-19 vaccination in patients with chronic lymphocytic leukemia.
Heterologous AD5-nCOV plus CoronaVac versus homologous CoronaVac vaccination: a randomized phase 4 trial.
Off-the-Shelf Third-Party Virus-Specific T Cell Therapy to Treat JC Polyomavirus Infection in Hematopoietic Stem Cell Transplantation Recipients.
WT1 epitope-specific IgG and IgM antibodies for immune-monitoring in patients with advanced sarcoma treated with a WT1 peptide cancer vaccine.
SARS-CoV-2 memory B and T cell profiles in mild COVID-19 convalescent patients.
Short-Term Immunogenicity Profiles and Predictors for Suboptimal Immune Responses in Patients with End-Stage Kidney Disease Immunized with Inactivated SARS-CoV-2 Vaccine.
Tumor RNA transfected DCs derived from iPS cells elicit cytotoxicity against cancer cells induced from colorectal cancer patients in vitro.
Hepatitis B vaccine co-administration influences the heterologous effects of neonatal BCG vaccination in a sex-differential manner.
Characterization of Teicoplanin-Specific T-Cells from Drug Naïve Donors Expressing HLA-A*32:01.
Development of a skin- and neuro-attenuated live vaccine for varicella.
Immunogenicity and safety of a fourth COVID-19 vaccination in rituximab-treated patients: an open-label extension study.
Assessing anti-SARS-CoV-2 cellular immunity in 571 vaccines by using an IFN-γ release assay.
Safety, immunogenicity and effect on viral rebound of HTI vaccines in early treated HIV-1 infection: a randomized, placebo-controlled phase 1 trial.
Heterologous Prime-boost of SARS-CoV-2 inactivated vaccine and mRNA BNT162b2 among Healthy Thai Adolescents.
T cells of colorectal cancer patients' stimulated by neoantigenic and cryptic peptides better recognize autologous tumor cells.
CD1a promotes systemic manifestations of skin inflammation.
The Autophagy Receptor TAX1BP1 (T6BP) improves antigen presentation by MHC-II molecules.
An engineered SARS-CoV-2 receptor-binding domain produced in Pichia pastoris as a candidate vaccine antigen.
Durable spike-specific T cell responses after different COVID-19 vaccination regimens are not further enhanced by booster vaccination.
Dynamics of Antibody and T Cell Immunity against SARS-CoV-2 Variants of Concern and the Impact of Booster Vaccinations in Previously Infected and Infection-Naïve Individuals.
Immunogenicity, Immune Dynamics, and Subsequent Response to the Booster Dose of Heterologous versus Homologous Prime-Boost Regimens with Adenoviral Vector and mRNA SARS-CoV-2 Vaccine among Liver Transplant Recipients: A Prospective Study.
T-cell responses to SARS-CoV-2 Omicron spike epitopes with mutations after the third booster dose of an inactivated vaccine.
SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway.
Blood Th17 cells and IL-17A as candidate biomarkers estimating the progression of cognitive impairment in stroke patients.
Impaired humoral and cellular response to primary COVID-19 vaccination in patients less than 2 years after allogeneic bone marrow transplant.
The phenotype of HLA-binding B cells from sensitized kidney transplant recipients correlates with clinically prognostic patterns of interferon-γ production against purified HLA proteins.
Safety and immunogenicity of a live-attenuated influenza virus vector-based intranasal SARS-CoV-2 vaccine in adults: randomised, double-blind, placebo-controlled, phase 1 and 2 trials.
Safety and immunogenicity of heterologous boost immunisation with an orally administered aerosolised Ad5-nCoV after two-dose priming with an inactivated SARS-CoV-2 vaccine in Chinese adults: a randomised, open-label, single-centre trial.
Prediction of Th1 and Cytotoxic T Lymphocyte Epitopes of Mycobacterium tuberculosis and Evaluation of Their Potential in the Diagnosis of Tuberculosis in a Mouse Model and in Humans.
SARS-CoV-2 vaccine-induced antibody and T cell response in SARS-CoV-1 survivors.
Protective Immunity of COVID-19 Vaccination with ChAdOx1 nCoV-19 Following Previous SARS-CoV-2 Infection: A Humoral and Cellular Investigation.
Adoptive Cellular Therapy with Autologous Tumor-Infiltrating Lymphocytes and T-cell Receptor-Engineered T Cells Targeting Common p53 Neoantigens in Human Solid Tumors.
Analysis of the Specific Immune Response after the Third Dose of mRNA COVID-19 Vaccines in Organ Transplant Recipients: Possible Spike-S1 Reactive IgA Signature in Protection from SARS-CoV-2 Infection.
HLA-B∗46 associates with rapid HIV disease progression in Asian cohorts and prominent differences in NK cell phenotype.
Adenoviral-based vaccine promotes neoantigen-specific CD8(+) T cell stemness and tumor rejection.
Identification of four novel T cell autoantigens and personal autoreactive profiles in multiple sclerosis.
In-situ scalable manufacturing of Epstein-Barr virus-specific T-cells using bioreactor with an expandable culture area (BECA).
Impaired humoral and T cell response to vaccination against SARS-CoV-2 in chronic myeloproliferative neoplasm patients treated with ruxolitinib.
Characterization of immune responses in fully vaccinated individuals after breakthrough infection with the SARS-CoV-2 delta variant.
Dynamics of Neutralizing Antibody and T-Cell Responses to SARS-CoV-2 and Variants of Concern after Primary Immunization with CoronaVac and Booster with BNT162b2 or ChAdOx1 in Health Care Workers.
Enhanced Cross-Reactive and Polyfunctional Effector-Memory T Cell Responses by ICVAX-a Human PD1-Based Bivalent HIV-1 Gag-p41 Mosaic DNA Vaccine.
Transcriptomic profiles of neoantigen-reactive T cells in human gastrointestinal cancers.
Neoantigen-specific CD4(+) T cells in human melanoma have diverse differentiation states and correlate with CD8(+) T cell, macrophage, and B cell function.
T cell mediated immunity against influenza H5N1 nucleoprotein, matrix and hemagglutinin derived epitopes in H5N1 survivors and non-H5N1 subjects.
Immune Characters and Plasticity of the Sentinel Lymph Node in Colorectal Cancer Patients.
Comparative analysis of the ex vivo IFN-gamma responses to CD8+ T cell epitopes within allelic forms of PfAMA1 in subjects with natural exposure to malaria.
Immune alterations in subacute sclerosing panencephalitis reflect an incompetent response to eliminate the measles virus.
Final results regarding the addition of dendritic cell vaccines to neoadjuvant chemotherapy in early HER2-negative breast cancer patients: clinical and translational analysis.
Oxidized-Desialylated Low-Density Lipoprotein Inhibits the Antitumor Functions of Lymphokine Activated Killer Cells.
HPV-16 E7-Specific Cellular Immune Response in Women With Cervical Intraepithelial Lesion Contributes to Viral Clearance: A Cross-Sectional and Longitudinal Clinical Study.
Adding Help to an HLA-A*24:02 Tumor-Reactive γδTCR Increases Tumor Control.
Latent CMV Infection Is Associated With Lower Influenza Virus-Specific Memory T-Cell Frequencies, but Not With an Impaired T-Cell Response to Acute Influenza Virus Infection.
Vγ9Vδ2 T Cells Concurrently Kill Cancer Cells and Cross-Present Tumor Antigens.
Differential Longevity of Memory CD4 and CD8 T Cells in a Cohort of the Mothers With a History of ZIKV Infection and Their Children.
An immunogenic first-in-human immune modulatory vaccine with PD-L1 and PD-L2 peptides is feasible and shows early signs of efficacy in follicular lymphoma.
Functional analysis of peripheral and intratumoral neoantigen-specific TCRs identified in a patient with melanoma.
Assessment of commonly used methods to determine myelin-reactivity of T cells in multiple sclerosis.
Distinct tumour antigen-specific T-cell immune response profiles at different hepatocellular carcinoma stages.
Intradermal ChAdOx1 Vaccine Following Two CoronaVac Shots: A Case Report.
HPV16 E6-specific T cell response and HLA-A alleles are related to the prognosis of patients with cervical cancer.
Virus-specific T cells for adenovirus infection after stem cell transplantation are highly effective and class II HLA restricted.
Monitoring cell-mediated immune responses in AAV gene therapy clinical trials using a validated IFN-γ ELISpot method.
A functional assay for serum detection of antibodies against SARS-CoV-2 nucleoprotein.
Rapid measurement of SARS-CoV-2 spike T cells in whole blood from vaccinated and naturally infected individuals.
Defining the RBPome of primary T helper cells to elucidate higher-order Roquin-mediated mRNA regulation.
SARS-CoV-2 vaccination in rituximab-treated patients: B cells promote humoral immune responses in the presence of T-cell-mediated immunity.
Boosting CAR T-cell responses in lymphoma by simultaneous targeting of CD40/4-1BB using oncolytic viral gene therapy.
High-affinity neoantigens correlate with better prognosis and trigger potent antihepatocellular carcinoma (HCC) activity by activating CD39(+)CD8(+) T cells.
Rational design of a hydrolysis-resistant mycobacterial phosphoglycolipid antigen presented by CD1c to T cells.
Safety, pharmacokinetics and antiviral activity of PGT121, a broadly neutralizing monoclonal antibody against HIV-1: a randomized, placebo-controlled, phase 1 clinical trial.
Patients with autoimmune polyendocrine syndrome type 1 have an increased susceptibility to severe herpesvirus infections.
HLA Class-II‒Restricted CD8(+) T Cells Contribute to the Promiscuous Immune Response in Dapsone-Hypersensitive Patients.
CD4+ T cells in the lungs of acute sarcoidosis patients recognize an Aspergillus nidulans epitope.
The evaluation of novel oral vaccines based on self-amplifying RNA lipid nanparticles (saRNA LNPs), saRNA transfected Lactobacillus plantarum LNPs, and saRNA transfected Lactobacillus plantarum to neutralize SARS-CoV-2 variants alpha and delta.
Novel HLA-B7-restricted human metapneumovirus epitopes enhance viral clearance in mice and are recognized by human CD8(+) T cells.
Innate-like Gene Expression of Lung-Resident Memory CD8(+) T Cells during Experimental Human Influenza: A Clinical Study.
Empirical identification and validation of tumor-targeting T cell receptors from circulation using autologous pancreatic tumor organoids.
The cellular immune response against Epstein-Barr virus decreases during ocrelizumab treatment.
SARS-CoV-2-reactive T-cell receptors isolated from convalescent COVID-19 patients confer potent T-cell effector function.
Immune responses to two and three doses of the BNT162b2 mRNA vaccine in adults with solid tumors.
DNA and modified vaccinia Ankara prime-boost vaccination generates strong CD8(+) T cell responses against minor histocompatibility antigen HA-1.
The Safety and Immunologic Effectiveness of the Live Varicella-Zoster Vaccine in Patients Receiving Tumor Necrosis Factor Inhibitor Therapy : A Randomized Controlled Trial.
Oncolytic herpes simplex virus type-1 expressing IL-12 efficiently replicates and kills human colorectal cancer cells.
Myeloid-derived suppressor cells and their association with vaccine immunogenicity in South African infants.
Immunogenicity and Safety of an Intradermal BNT162b2 mRNA Vaccine Booster after Two Doses of Inactivated SARS-CoV-2 Vaccine in Healthy Population.
Challenging the Conventional Interpretation of HCMV Seronegativity.
The Role of In Vivo and Ex Vivo Diagnostic Tools in Severe Delayed Immune-Mediated Adverse Antibiotic Drug Reactions.
Pre-existing immune status associated with response to combination of sipuleucel-T and ipilimumab in patients with metastatic castration-resistant prostate cancer.
T cell mediated hypersensitivity to previously tolerated iodinated contrast media precipitated by introduction of atezolizumab.
Unique Cholangiocyte-Targeted IgM Autoantibodies Correlate With Poor Outcome in Biliary Atresia.
Weighting tumor-specific TCR repertoires as a classifier to stratify the immunotherapy delivery in non-small cell lung cancers.
Stepwise Reversal of Immune Dysregulation Due to STAT1 Gain-of-Function Mutation Following Ruxolitinib Bridge Therapy and Transplantation.
Failure of Viral-Specific T Cells Administered in Pre-transplant Settings in Children with Inborn Errors of Immunity.
Combined inhibition of PD-1/PD-L1, Lag-3, and Tim-3 axes augments antitumor immunity in gastric cancer-T cell coculture models.
Targeted Delivery of BZLF1 to DEC205 Drives EBV-Protective Immunity in a Spontaneous Model of EBV-Driven Lymphoproliferative Disease.
Pre-existing T Cell Memory against Zika Virus.
Quality Verification with a Cluster-Controlled Manufacturing System to Generate Monocyte-Derived Dendritic Cells.
Persistent COVID-19 Symptoms Minimally Impact the Development of SARS-CoV-2-Specific T Cell Immunity.
Highly conserved, non-human-like, and cross-reactive SARS-CoV-2 T cell epitopes for COVID-19 vaccine design and validation.
A phase 1, single centre, open label, escalating dose study to assess the safety, tolerability and immunogenicity of a therapeutic human papillomavirus (HPV) DNA vaccine (AMV002) for HPV-associated head and neck cancer (HNC).
Clinical Trial of a Cancer Vaccine Targeting VEGF and KIF20A in Advanced Biliary Tract Cancer.
Resident and circulating memory T cells persist for years in melanoma patients with durable responses to immunotherapy.
The mutational load and a T-cell inflamed tumour phenotype identify ovarian cancer patients rendering tumour-reactive T cells from PD-1(+) tumour-infiltrating lymphocytes.
Shared recognition of citrullinated tenascin-C peptides by T and B cells in rheumatoid arthritis.
SARS-CoV-2 mutations in MHC-I-restricted epitopes evade CD8(+) T cell responses.
Immune memory in convalescent patients with asymptomatic or mild COVID-19.
Stability of interleukin-1β, -4, -6, -8, -10, -13, interferon-γ and tumor necrosis factor-α in human sera after repetitive freeze-thaw cycles and long storage.
T Cells Specific for a Mycobacterial Glycolipid Expand after Intravenous Bacillus Calmette-Guérin Vaccination.
Persistence of SARS-CoV-2-specific B and T cell responses in convalescent COVID-19 patients 6-8 months after the infection.
Two Cases of anti-PIT-1 Hypophysitis Exhibited as a Form of Paraneoplastic Syndrome not Associated With Thymoma.
TGM4: an immunogenic prostate-restricted antigen.
Circulating leukocyte-platelet complexes as a predictive biomarker for the development of immune-related adverse events in advanced non-small cell lung cancer patients receiving anti-PD-(L)1 blocking agents.
CD52/GPI- T-Cells Are Enriched for Alloreactive Specificity and Predict Acute Graft-Versus-Host-Disease After Stem Cell Transplantation.
Whole blood interleukin-2 release test to detect and characterize rare circulating gluten-specific T cell responses in coeliac disease.
Deep learning boosts sensitivity of mass spectrometry-based immunopeptidomics.
Cellular Immune Response Induced by DNA Immunization of Mice with Drug Resistant Integrases of HIV-1 Clade A Offers Partial Protection against Growth and Metastatic Activity of Integrase-Expressing Adenocarcinoma Cells.
SARS-CoV-2-specific T cell memory is sustained in COVID-19 convalescent patients for 10 months with successful development of stem cell-like memory T cells.
Neoantigens elicit T cell responses in breast cancer.
Correlates of Neutralization against SARS-CoV-2 Variants of Concern by Early Pandemic Sera.
Immunogenicity of COVID-19 mRNA Vaccines in Pregnant and Lactating Women.
Manufacturing NKG2D CAR-T cells with piggyBac transposon vectors and K562 artificial antigen-presenting cells.
Reduced blood-stage malaria growth and immune correlates in humans following RH5 vaccination.
Genome-Wide B Cell, CD4(+), and CD8(+) T Cell Epitopes That Are Highly Conserved between Human and Animal Coronaviruses, Identified from SARS-CoV-2 as Targets for Preemptive Pan-Coronavirus Vaccines.
Bi/tri-specific antibodies (HN-Fc-CD16 and HN-Fc-IL-15-CD16) cross-linking natural killer (NK)-CD16 and Newcastle Disease Virus (NDV)-HN, enhanced NK activation for cancer immunotherapy.
Phase 1 study of safety, tolerability and immunogenicity of the human telomerase (hTERT)-encoded DNA plasmids INO-1400 and INO-1401 with or without IL-12 DNA plasmid INO-9012 in adult patients with solid tumors.
Neoantigen vaccination induces clinical and immunologic responses in non-small cell lung cancer patients harboring EGFR mutations.
Identification of neoantigen-reactive T lymphocytes in the peripheral blood of a patient with glioblastoma.
Hepatitis E Infection in a Longitudinal Cohort of Hepatitis C Virus and HCV/HIV Coinfected Persons.
Immune responses to a single dose of the AZD1222/Covishield vaccine in health care workers.
Impact of SARS-CoV-2 variants on the total CD4(+) and CD8(+) T cell reactivity in infected or vaccinated individuals.
Young infants exhibit robust functional antibody responses and restrained IFN-γ production to SARS-CoV-2.
Cell-Associated HIV Cross-Presentation by Plasmacytoid Dendritic Cells Is Potentiated by Noncognate CD8(+) T Cell Preactivation.
Safety and immunogenicity of INO-4800 DNA vaccine against SARS-CoV-2: A preliminary report of an open-label, Phase 1 clinical trial.
Cellular Immunity in COVID-19 Convalescents with PCR-Confirmed Infection but with Undetectable SARS-CoV-2-Specific IgG.
Identification of new cytokine combinations for antigen-specific T-cell therapy products via a high-throughput multi-parameter assay.
SARS-CoV-2-derived peptides define heterologous and COVID-19-induced T cell recognition.
Safety and immunogenicity of an inactivated SARS-CoV-2 vaccine, BBIBP-CorV: a randomised, double-blind, placebo-controlled, phase 1/2 trial.
Simultaneous testing of immunological sensitization to multiple antigens in sarcoidosis reveals an association with inorganic antigens specifically related to a fibrotic phenotype.
Restoration of T-cell Effector Function, Depletion of Tregs, and Direct Killing of Tumor Cells: The Multiple Mechanisms of Action of a-TIGIT Antagonist Antibodies.
Dissemination of Mycobacterium tuberculosis is associated to a SIGLEC1 null variant that limits antigen exchange via trafficking extracellular vesicles.
A biomimetic assay platform for the interrogation of antigen-dependent anti-tumor T-cell function.
Human skin is colonized by T cells that recognize CD1a independently of lipid.
Evaluation of the Expression of CCR5 and CX3CR1 Receptors and Correlation with the Functionality of T Cells in Women infected with ZIKV during Pregnancy.
Constitutively Activated DAP12 Induces Functional Anti-Tumor Activation and Maturation of Human Monocyte-Derived DC.
Characterization of ascites- and tumor-infiltrating γδ T cells reveals distinct repertoires and a beneficial role in ovarian cancer.
The TCR repertoire of α-synuclein-specific T cells in Parkinson's disease is surprisingly diverse.
Safety, tolerability, and immunogenicity of an inactivated SARS-CoV-2 vaccine in healthy adults aged 18-59 years: a randomised, double-blind, placebo-controlled, phase 1/2 clinical trial.
Cytotoxic T cells isolated from healthy donors and cancer patients kill TGFβ-expressing cancer cells in a TGFβ-dependent manner.
In vivo dynamics and adaptation of HTLV-1-infected clones under different clinical conditions.
Identification of the association between HBcAg-specific T cell and viral control in chronic HBV infection using a cultured ELISPOT assay.
Early induction of functional SARS-CoV-2-specific T cells associates with rapid viral clearance and mild disease in COVID-19 patients.
HIV-specific T cell responses reflect substantive in vivo interactions with antigen despite long-term therapy.
First-in-Human Phase I Clinical Trial of an SFV-Based RNA Replicon Cancer Vaccine against HPV-Induced Cancers.
Ageing of Immune System and Response to a Live-Attenuated Herpes Zoster Vaccine in Lung Transplant Candidates.
Characterization of the Class I MHC Peptidome Resulting From DNCB Exposure of HaCaT Cells.
Characterization of a Unique γδ T-Cell Subset as a Specific Marker of Cytomegalovirus Infection Severity.
Vaccination against PD-L1 with IO103 a Novel Immune Modulatory Vaccine in Basal Cell Carcinoma: A Phase IIa Study.
Prediction of neo-epitope immunogenicity reveals TCR recognition determinants and provides insight into immunoediting.
Neoadjuvant anti-OX40 (MEDI6469) therapy in patients with head and neck squamous cell carcinoma activates and expands antigen-specific tumor-infiltrating T cells.
Characterization of humoral and SARS-CoV-2 specific T cell responses in people living with HIV.
Cellular and humoral immune response after mRNA-1273 SARS-CoV-2 vaccine in liver and heart transplant recipients.
Adaptive immunity and neutralizing antibodies against SARS-CoV-2 variants of concern following vaccination in patients with cancer: The CAPTURE study.
Acute exercise increases immune responses to SARS CoV-2 in a previously infected man.
Cytotoxic CD4+ T-cells specific for EBV capsid antigen BORF1 are maintained in long-term latently infected healthy donors.
Hydroxychloroquine inhibits the mitochondrial antioxidant system in activated T cells.
Kaposi's sarcoma-associated herpesvirus T cell responses in HIV seronegative individuals from rural Uganda.
Platelet PD-L1 reflects collective intratumoral PD-L1 expression and predicts immunotherapy response in non-small cell lung cancer.
Phase Ib study of patients with metastatic castrate-resistant prostate cancer treated with different sequencing regimens of atezolizumab and sipuleucel-T.
IL-7 expands lymphocyte populations and enhances immune responses to sipuleucel-T in patients with metastatic castration-resistant prostate cancer (mCRPC).
Safety and immunogenicity of the ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 in HIV infection: a single-arm substudy of a phase 2/3 clinical trial.
ELISpot assay as a diagnostic tool in drug hypersensitivity reactions.
Alternative Evaluation of an ELISPOT Assay Using Cytokine Activity as a Novel Parameter.
Tumor-infiltrating lymphocyte treatment for anti-PD-1-resistant metastatic lung cancer: a phase 1 trial.
Cytokine release syndrome in a patient with colorectal cancer after vaccination with BNT162b2.
Preexisting and Post-COVID-19 Immune Responses to SARS-CoV-2 in Patients with Cancer.
Deciphering Adverse Drug Reactions: In Vitro Priming and Characterization of Vancomycin-Specific T Cells From Healthy Donors Expressing HLA-A*32:01.
The RECOVAC IR study: the immune response and safety of the mRNA-1273 COVID-19 vaccine in patients with chronic kidney disease, on dialysis or living with a kidney transplant.
Development of a novel ZIKV vaccine comprised of immunodominant CD4+ and CD8+ T cell epitopes identified through comprehensive epitope mapping in Zika virus infected mice.
A high-affinity human TCR-like antibody detects celiac disease gluten peptide-MHC complexes and inhibits T cell activation.
Two doses of SARS-CoV-2 vaccination induce robust immune responses to emerging SARS-CoV-2 variants of concern.
Comparison of SARS-CoV-2- and HCoV-Specific T Cell Response Using IFN-γ ELISpot.
A vaccine targeting mutant IDH1 in newly diagnosed glioma.
Comprehensive epitope mapping using polyclonally expanded human CD8 T cells and a two-step ELISpot assay for testing large peptide libraries.
Illuminating the in vitro effects of Epstein-Barr virus and vitamin D on immune response in multiple sclerosis patients.
Longitudinal antibody and T cell responses in Ebola virus disease survivors and contacts: an observational cohort study.
Phase I studies of peptide vaccine cocktails derived from GPC3, WDRPUH and NEIL3 for advanced hepatocellular carcinoma.
Prognostic significance of interleukin-17A-producing colorectal tumour antigen-specific T cells.
T cell assays differentiate clinical and subclinical SARS-CoV-2 infections from cross-reactive antiviral responses.
T cell and antibody kinetics delineate SARS-CoV-2 peptides mediating long-term immune responses in COVID-19 convalescent individuals.
Optimized polyepitope neoantigen DNA vaccines elicit neoantigen-specific immune responses in preclinical models and in clinical translation.
Atypical acute myeloid leukemia-specific transcripts generate shared and immunogenic MHC class-I-associated epitopes.
Noncytotoxic Inhibition of the Immunoproteasome Regulates Human Immune Cells In Vitro and Suppresses Cutaneous Inflammation in the Mouse.
Rift Valley fever virus vaccination induces long-lived, antigen-specific human T cell responses.
Immunization with full-length Plasmodium falciparum merozoite surface protein 1 is safe and elicits functional cytophilic antibodies in a randomized first-in-human trial.
Optimising T cell (re)boosting strategies for adenoviral and modified vaccinia Ankara vaccine regimens in humans.
Profound Functional Suppression of Tumor-Infiltrating T-Cells in Ovarian Cancer Patients Can Be Reversed Using PD-1-Blocking Antibodies or DARPin® Proteins.
IMRAS-A clinical trial of mosquito-bite immunization with live, radiation-attenuated P. falciparum sporozoites: Impact of immunization parameters on protective efficacy and generation of a repository of immunologic reagents.
Peptide Vaccination Against PD-L1 With IO103 a Novel Immune Modulatory Vaccine in Multiple Myeloma: A Phase I First-in-Human Trial.
The Safety and Efficacy of Live Viral Vaccines in Patients With Cartilage-Hair Hypoplasia.
Pregnancy Gestation Impacts on HIV-1-Specific Granzyme B Response and Central Memory CD4 T Cells.
Mucosal-Associated Invariant T Cells Develop an Innate-Like Transcriptomic Program in Anti-mycobacterial Responses.
Elevated nucleoprotein-induced interferon-γ release in COVID-19 patients detected in a SARS-CoV-2 enzyme-linked immunosorbent spot assay.
An RNA vaccine drives immunity in checkpoint-inhibitor-treated melanoma.
Reinventing the nutraceutical value of gluten: The case of l-theanine-gluten as a potential alternative to the gluten exclusion diet in celiac disease.
Impaired Cellular Immune Responses During the First Week of Severe Acute Influenza Infection.
The MAIT TCRβ chain contributes to discrimination of microbial ligand.
Breast cancer-induced immune suppression in the sentinel lymph node is effectively countered by CpG-B in conjunction with inhibition of the JAK2/STAT3 pathway.
Characterization of amoxicillin and clavulanic acid specific T-cell clones from patients with immediate drug hypersensitivity.
COVID-19 vaccine BNT162b1 elicits human antibody and T(H)1 T cell responses.
Systemic and respiratory T-cells induced by seasonal H1N1 influenza protect against pandemic H2N2 in ferrets.
Selective and cross-reactive SARS-CoV-2 T cell epitopes in unexposed humans.
Healthy Donors Harbor Memory T Cell Responses to RAS Neo-Antigens.
The vitamin D analogue calcipotriol promotes an anti-tumorigenic phenotype of human pancreatic CAFs but reduces T cell mediated immunity.
Robust T Cell Immunity in Convalescent Individuals with Asymptomatic or Mild COVID-19.
In vitro 4-1BB stimulation promotes expansion of CD8(+) tumor-infiltrating lymphocytes from various sarcoma subtypes.
Immune suppression caused by PD-L2 expression on tumor cells in gastric cancer.
Antigen-reactive regulatory T cells can be expanded in vitro with monocytes and anti-CD28 and anti-CD154 antibodies.
Hazara virus and Crimean-Congo Hemorrhagic Fever Virus show a different pattern of entry in fully-polarized Caco-2 cell line.
Varicella-zoster-virus vaccination of immunosuppressed children with inflammatory bowel disease or autoimmune hepatitis: A prospective observational study.
Virus-specific T-cell therapy to treat BK polyomavirus infection in bone marrow and solid organ transplant recipients.
Identification and Characterization of CD4(+) T Cell Epitopes after Shingrix Vaccination.
mRNA vaccine-induced neoantigen-specific T cell immunity in patients with gastrointestinal cancer.
TruNeo: an integrated pipeline improves personalized true tumor neoantigen identification.
Identification of Novel Yellow Fever Class II Epitopes in YF-17D Vaccinees.
HLA DRB1*15:01-DQB1*06:02-Restricted Human CD4+ T Cells Are Selectively Activated With Amoxicillin-Peptide Adducts.
Personalized neoantigen-based immunotherapy for advanced collecting duct carcinoma: case report.
Characterisation of clinical and immune reactivity to barley and rye ingestion in children with coeliac disease.
Reader-free ELISPOT assay for immuno-monitoring in peptide-based cancer vaccine immunotherapy.
Cathepsin S Alterations Induce a Tumor-Promoting Immune Microenvironment in Follicular Lymphoma.
Ligand-dependent downregulation of MR1 cell surface expression.
Phase II study of α-galactosylceramide-pulsed antigen-presenting cells in patients with advanced or recurrent non-small cell lung cancer.
Human Immune Responses to Melioidosis and Cross-Reactivity to Low-Virulence Burkholderia Species, Thailand(1).
A novel α-fetoprotein-derived helper T-lymphocyte epitope with strong immunogenicity in patients with hepatocellular carcinoma.
Assessing the impact of AGS-004, a dendritic cell-based immunotherapy, and vorinostat on persistent HIV-1 Infection.
Human Immunodeficiency Virus Exposure but Not Early Cytomegalovirus Infection Is Associated With Increased Hospitalization and Decreased Memory T-Cell Responses to Tetanus Vaccine.
Safety, immunogenicity, and clinical efficacy of durvalumab in combination with folate receptor alpha vaccine TPIV200 in patients with advanced ovarian cancer: a phase II trial.
Oncolytic Newcastle disease virus activation of the innate immune response and priming of antitumor adaptive responses in vitro.
Experimental Antiglomerular Basement Membrane GN Induced by a Peptide from Actinomyces.
Quantitative and Qualitative Perturbations of CD8(+) MAITs in Healthy Mycobacterium tuberculosis-Infected Individuals.
Detection of SARS-CoV-2-Specific Humoral and Cellular Immunity in COVID-19 Convalescent Individuals.
Human CLEC9A antibodies deliver NY-ESO-1 antigen to CD141(+) dendritic cells to activate naïve and memory NY-ESO-1-specific CD8(+) T cells.
Experimental treatment of colorectal cancer in mice with human T cells electroporated with NKG2D RNA CAR.
Toll-like receptor dual-acting agonists are potent inducers of PBMC-produced cytokines that inhibit hepatitis B virus production in primary human hepatocytes.
Interrogating the recognition landscape of a conserved HIV-specific TCR reveals distinct bacterial peptide cross-reactivity.
Cancer Antigen Discovery Is Enabled by RNA Sequencing of Highly Purified Malignant and Nonmalignant Cells.
Cinnamon extract inhibits allergen-specific immune responses in human and murine allergy models.
Interferon-γ Secretion Enzyme-Linked Immunospot Assay Determined Among Human T Cell Lymphotropic Virus Type 1-Infected Subjects: A Potential Laboratory Marker for Early HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis Diagnosis.
T cell receptor cross-reactivity between gliadin and bacterial peptides in celiac disease.
CD39(+) regulatory T cells modulate the immune response to carbamazepine in HLA-B*15:02 carriers.
Cell-Mediated Immunity Generated in Response to a Purified Inactivated Vaccine for Dengue Virus Type 1.
A phase I trial evaluating the safety and immunogenicity of a candidate tuberculosis vaccination regimen, ChAdOx1 85A prime - MVA85A boost in healthy UK adults.
Characterization of virus-mediated immunogenic cancer cell death and the consequences for oncolytic virus-based immunotherapy of cancer.
Automated Flow Synthesis of Tumor Neoantigen Peptides for Personalized Immunotherapy.
Epitope-specific airway-resident CD4+ T cell dynamics during experimental human RSV infection.
Evaluation of Newcastle disease virus mediated dendritic cell activation and cross-priming tumor-specific immune responses ex vivo.
Intratumoral Plasmid IL12 Electroporation Therapy in Patients with Advanced Melanoma Induces Systemic and Intratumoral T-cell Responses.
Human labour is associated with altered regulatory T cell function and maternal immune activation.
A high infectious simian adenovirus type 23 vector based vaccine efficiently protects common marmosets against Zika virus infection.
Mobilization of pre-existing polyclonal T cells specific to neoantigens but not self-antigens during treatment of a patient with melanoma with bempegaldesleukin and nivolumab.
Immunostimulatory oncolytic virotherapy for multiple myeloma targeting 4-1BB and/or CD40.
Antigenic competition in the generation of multi-virus-specific cell lines for immunotherapy of human cytomegalovirus, polyomavirus BK, Epstein-Barr virus and adenovirus infection in haematopoietic stem cell transplant recipients.
Designed Ankyrin Repeat Protein (DARPin) to target chimeric antigen receptor (CAR)-redirected T cells towards CD4(+) T cells to reduce the latent HIV(+) cell reservoir.
Comprehensive analysis of T cell immunodominance and immunoprevalence of SARS-CoV-2 epitopes in COVID-19 cases.
Interferon-α-Induced Dendritic Cells Generated with Human Platelet Lysate Exhibit Elevated Antigen Presenting Ability to Cytotoxic T Lymphocytes.
Discordant neutralizing antibody and T cell responses in asymptomatic and mild SARS-CoV-2 infection.
HLA Class II Genotype Does Not Affect the Myelin Responsiveness of Multiple Sclerosis Patients.
Shared Immunogenic Poly-Epitope Frameshift Mutations in Microsatellite Unstable Tumors.
Healthy donor T cell responses to common cold coronaviruses and SARS-CoV-2.
Rapid tumor vaccine using Toll-like receptor-activated ovarian cancer ascites monocytes.
SARS-CoV-2-specific T cell immunity in cases of COVID-19 and SARS, and uninfected controls.
EBV renders B cells susceptible to HIV-1 in humanized mice.
Generation of high-affinity CMV-specific T cells for adoptive immunotherapy using IL-2, IL-15, and IL-21.
Immunogenicity and safety of a recombinant adenovirus type-5-vectored COVID-19 vaccine in healthy adults aged 18 years or older: a randomised, double-blind, placebo-controlled, phase 2 trial.
Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial.
Coordinated In Vitro Release of Granulysin, Perforin and IFN-γ in TB and HIV/TB Co-Infection Associated with Clinical Outcomes before and after Anti-TB Treatment.
Adaptive immune responses to SARS-CoV-2 infection in severe versus mild individuals.
Specific T-cell immune responses against colony-forming cells including leukemic progenitor cells of AML patients were increased by immune checkpoint inhibition.
Bispecific antibody activated T cells: A newly developed T cells with enhanced proliferation ability and cytotoxicity.
Efficacy, immunogenicity, and safety of an oral influenza vaccine: a placebo-controlled and active-controlled phase 2 human challenge study.
Early Induction of Cross-Reactive CD8+ T-Cell Responses in Tonsils After Live-Attenuated Influenza Vaccination in Children.
Sublethal Radiation Affects Antigen Processing and Presentation Genes to Enhance Immunogenicity of Cancer Cells.
α-Synuclein-specific T cell reactivity is associated with preclinical and early Parkinson's disease.
Neoantigen responses, immune correlates, and favorable outcomes after ipilimumab treatment of patients with prostate cancer.
A durable protective immune response to wild-type measles virus infection of macaques is due to viral replication and spread in lymphoid tissues.
Prominent T-Cell Responses against the Acetylcholine Receptor ε Subunit in Myasthenia Gravis.
TRAV1-2(+) CD8(+) T-cells including oligoconal expansions of MAIT cells are enriched in the airways in human tuberculosis.
Variability in German Cockroach Extract Composition Greatly Impacts T Cell Potency in Cockroach-Allergic Donors.
Successful engraftment of gene-corrected hematopoietic stem cells in non-conditioned patients with Fanconi anemia.
Generation of donor-derived Wilms tumor antigen 1-specific cytotoxic T lymphocytes with potent anti-leukemia activity for somatic cell therapy in children given haploidentical stem cell transplantation: a feasibility pre-clinical study.
E40, a novel microbial protease efficiently detoxifying gluten proteins, for the dietary management of gluten intolerance.
Identification of Immunodominant HIV-1 Epitopes Presented by HLA-C*12:02, a Protective Allele, Using an Immunopeptidomics Approach.
Functional immune response to influenza H1N1 in children and adults after live attenuated influenza virus vaccination.
Development of a novel human phage display-derived anti-LAG3 scFv antibody targeting CD8(+) T lymphocyte exhaustion.
Enhanced IFN-γ, but not IL-2, response to Mycobacterium tuberculosis antigens in HIV/latent TB co-infected patients on long-term HAART.
Robust prediction of HLA class II epitopes by deep motif deconvolution of immunopeptidomes.
Secondary resistance to immunotherapy associated with β-catenin pathway activation or PTEN loss in metastatic melanoma.
Antigenic competition in CD4(+) T cell responses in a randomized, multicenter, double-blind clinical HIV vaccine trial.
A PBMC-Based System to Assess Human T Cell Responses to Influenza Vaccine Candidates In Vitro.
Increased CD83 expression of CD34-positive monocytes in donors during peripheral blood stem cell mobilization in humans.
Tofacitinib modulates the VZV-specific CD4+ T cell immune response in vitro in lymphocytes of patients with rheumatoid arthritis.
CD1b presents self and Borrelia burgdorferi diacylglycerols to human T cells.
Identification and characterization of a naïve CD8+ T cell repertoire for benzylpenicillin.
Type 1-programmed dendritic cells drive antigen-specific latency reversal and immune elimination of persistent HIV-1.
UVB-induced depletion of donor-derived dendritic cells prevents allograft rejection of immune-privileged hair follicles in humanized mice.
Therapeutic Vaccination Refocuses T-cell Responses Towards Conserved Regions of HIV-1 in Early Treated Individuals (BCN 01 study).
Robust Identification of Suitable T-Cell Subsets for Personalized CMV-Specific T-Cell Immunotherapy Using CD45RA and CD62L Microbeads.
MR1 recycling and blockade of endosomal trafficking reveal distinguishable antigen presentation pathways between Mycobacterium tuberculosis infection and exogenously delivered antigens.
Evaluating in vivo efficacy - toxicity profile of TEG001 in humanized mice xenografts against primary human AML disease and healthy hematopoietic cells.
Contrasting Roles of the PD-1 Signaling Pathway in Dendritic Cell-Mediated Induction and Regulation of HIV-1-Specific Effector T Cell Functions.
Development of T cell immunity to norovirus and rotavirus in children under five years of age.
Role of Mycobacterium avium lysate INF-γ, IL-17, and IL-2 ELISPOT assays in diagnosing nontuberculous mycobacteria lymphadenitis in children.
Healthy Donors Exhibit a CD4 T Cell Repertoire Specific to the Immunogenic Human Hormone H2-Relaxin before Injection.
Immunogenicity and safety of a new live attenuated herpes zoster vaccine (NBP608) compared to Zostavax® in healthy adults aged 50 years and older.
Five Years of Successful Inducible Transgene Expression Following Locoregional Adeno-Associated Virus Delivery in Nonhuman Primates with No Detectable Immunity.
Role of human and porcine MHC DRB1 alleles in determining the intensity of individual human anti-pig T-cell responses.
Investigation of the role of typhoid toxin in acute typhoid fever in a human challenge model.
Molecular properties of gp100-reactive T-cell receptors drive the cytokine profile and antitumor efficacy of transgenic host T cells.
Evaluation of interleukin-12 receptor β1 and interferon gamma receptor 1 deficiency in patients with disseminated BCG infection.
Persistence of Varicella-Zoster Virus Cell-Mediated Immunity After the Administration of a Second Dose of Live Herpes Zoster Vaccine.
A T-cell receptor escape channel allows broad T-cell response to CD1b and membrane phospholipids.
Inhibition of Heme Oxygenase-1 Activity Enhances Wilms Tumor-1-Specific T-Cell Responses in Cancer Immunotherapy.
Dose Optimization of H56:IC31 Vaccine for Tuberculosis-Endemic Populations. A Double-Blind, Placebo-controlled, Dose-Selection Trial.
MicroRNAs of Epstein-Barr Virus Attenuate T-Cell-Mediated Immune Control In Vivo.
Impairment of Vα24-Jα18(+)Vβ11(+) natural killer T cells in adult acute lymphoblastic leukemia patients.
The nature of the human T cell response to the cancer antigen 5T4 is determined by the balance of regulatory and inflammatory T cells of the same antigen-specificity: implications for vaccine design.
In vitro analysis of immunomodulatory effects of mesenchymal stem cell- and tumor cell -derived exosomes on recall antigen-specific responses.
Specific T-cell receptor gene transfer enhances immune response: A potential therapeutic strategy for the control of human cytomegalovirus infection in immunocompromised patients.
Neoantigenic Potential of Complex Chromosomal Rearrangements in Mesothelioma.
Tumour-reactive T cell subsets in the microenvironment of ovarian cancer.
Mechanisms of Abrupt Loss of Virus Control in a Cohort of Previous HIV Controllers.
Efficacy of PD-1 blockade in cervical cancer is related to a CD8(+)FoxP3(+)CD25(+) T-cell subset with operational effector functions despite high immune checkpoint levels.
Interferon Alpha Enhances NK Cell Function and the Suppressive Capacity of HIV-Specific CD8(+) T Cells.
50-Gy Stereotactic Body Radiation Therapy to the Dominant Intraprostatic Nodule: Results From a Phase 1a/b Trial.
Neoantigen-specific immunity in low mutation burden colorectal cancers of the consensus molecular subtype 4.
Human leukocyte antigen (HLA) class II peptide flanking residues tune the immunogenicity of a human tumor-derived epitope.
Early suppression of peripheral mononuclear blood cells in sepsis in response to stimulation with cytomegalovirus, OKT3, and pokeweed mitogen.
The association of allergic sensitization patterns in early childhood with disease manifestations and immunological reactivity at 10 years of age.
The effects of CCR7 and related signaling pathways on Leishmania major -infected human dendritic cells.
Generation of Zika virus-specific T cells from seropositive and virus-naïve donors for potential use as an autologous or "off-the-shelf" immunotherapeutic.
Myelin oligodendrocyte glycoprotein revisited-sensitive detection of MOG-specific T-cells in multiple sclerosis.
Chaperones of the class I peptide-loading complex facilitate the constitutive presentation of endogenous antigens on HLA-DP(84GGPM87).
The Effect of Age on the Immunogenicity of the Live Attenuated Zoster Vaccine Is Predicted by Baseline Regulatory T Cells and Varicella-Zoster Virus-Specific T Cell Immunity.
Incomplete functional T-cell reconstitution in immunological non-responders at one year after initiation of antiretroviral therapy possibly predisposes them to infectious diseases.
Leukoreduction system chambers are a reliable cellular source for the manufacturing of T-cell therapeutics.
HIV-1 reservoirs in urethral macrophages of patients under suppressive antiretroviral therapy.
Effective Suppression of HIV-1 Replication by Cytotoxic T Lymphocytes Specific for Pol Epitopes in Conserved Mosaic Vaccine Immunogens.
Characterization of Healthy Donor-Derived T-Cell Responses Specific to Telaprevir Diastereomers.
Immune Response and Intraocular Inflammation in Patients With Leber Hereditary Optic Neuropathy Treated With Intravitreal Injection of Recombinant Adeno-Associated Virus 2 Carrying the ND4 Gene: A Secondary Analysis of a Phase 1/2 Clinical Trial.
KIR3DL1-Negative CD8 T Cells and KIR3DL1-Negative Natural Killer Cells Contribute to the Advantageous Control of Early Human Immunodeficiency Virus Type 1 Infection in HLA-B Bw4 Homozygous Individuals.
A novel prostate cancer immunotherapy using prostate-specific antigen peptides and Candida skin test reagent as an adjuvant.
A heterogeneous human immunodeficiency virus-like particle (VLP) formulation produced by a novel vector system.
DNA immunization site determines the level of gene expression and the magnitude, but not the type of the induced immune response.
The effect of acylation with fatty acids and other modifications on HLA class II:peptide binding and T cell stimulation for three model peptides.
Randomized phase I trial HIV-CORE 003: Depletion of serum amyloid P component and immunogenicity of DNA vaccination against HIV-1.
Microbiota epitope similarity either dampens or enhances the immunogenicity of disease-associated antigenic epitopes.
Cross-reactive microbial peptides can modulate HIV-specific CD8+ T cell responses.
Immunotherapy with cancer peptides in combination with intravesical bacillus Calmette-Guerin for patients with non-muscle invasive bladder cancer.
High background in ELISpot assays is associated with elevated levels of immune activation in HIV-1-seronegative individuals in Nairobi.
Fumarate hydratase-specific T cell response in Chinese patients with autoimmune hepatitis.
Immune response to human telomerase reverse transcriptase-derived helper T cell epitopes in hepatocellular carcinoma patients.
Combined Skin and Muscle DNA Priming Provides Enhanced Humoral Responses to a Human Immunodeficency Virus Type 1 Clade C Envelope Vaccine.
Retinal AAV8-RS1 Gene Therapy for X-Linked Retinoschisis: Initial Findings from a Phase I/IIa Trial by Intravitreal Delivery.
A randomized phase II clinical trial of dendritic cell vaccination following complete resection of colon cancer liver metastasis.
RNA editing derived epitopes function as cancer antigens to elicit immune responses.
Long-term remission despite clonal expansion of replication-competent HIV-1 isolates.
Memory B Cells Activate Brain-Homing, Autoreactive CD4(+) T Cells in Multiple Sclerosis.
Enterobacteriaceae are essential for the modulation of colitis severity by fungi.
A novel allogeneic off-the-shelf dendritic cell vaccine for post-remission treatment of elderly patients with acute myeloid leukemia.
Isolated adrenocorticotropic hormone deficiency as a form of paraneoplastic syndrome.
Enhanced detection of neoantigen-reactive T cells targeting unique and shared oncogenes for personalized cancer immunotherapy.
Utilizing TAPBPR to promote exogenous peptide loading onto cell surface MHC I molecules.
Immune landscape and in vivo immunogenicity of NY-ESO-1 tumor antigen in advanced neuroblastoma patients.
Antisense-Derived HIV-1 Cryptic Epitopes Are Not Major Drivers of Viral Evolution during the Acute Phase of Infection.
Th1 memory differentiates recombinant from live herpes zoster vaccines.
Ex Vivo Generation of Donor Antigen-Specific Immunomodulatory Cells: A Comparison Study of Anti-CD80/86 mAbs and CTLA4-lg Costimulatory Blockade.
Cytokines concentrations in serum samples from allergic children-Multiple analysis to define biomarkers for better diagnosis of allergic inflammatory process.
Assessing and screening for T-cell epitopes from Mycobacterium tuberculosis RD2 proteins for the diagnosis of active tuberculosis.
Low-Density Lipoprotein-Reactive T Cells Regulate Plasma Cholesterol Levels and Development of Atherosclerosis in Humanized Hypercholesterolemic Mice.
CMV and EBV targets recognized by tumor-infiltrating B lymphocytes in pancreatic cancer and brain tumors.
Strong and frequent T-cell responses to the minor allergen Phl p 12 in Spanish patients IgE-sensitized to Profilins.
The effect of splenectomy on the levels of PCV-13-induced memory B- and T cells.
IgG response to MHC class I epitope peptides is a quantitative predictive biomarker in the early course of treatment of colorectal cancer using therapeutic peptides.
Identification of two novel foot-and-mouth disease virus cytotoxic T lymphocyte epitopes that can bind six SLA-I proteins.
Heat shock protein peptide complex-96 vaccination for newly diagnosed glioblastoma: a phase I, single-arm trial.
DOT1L inhibition attenuates graft-versus-host disease by allogeneic T cells in adoptive immunotherapy models.
Large-scale expansion of Vγ9Vδ2 T cells with engineered K562 feeder cells in G-Rex vessels and their use as chimeric antigen receptor-modified effector cells.
Human papilloma virus-specific T cells can be generated from naïve T cells for use as an immunotherapeutic strategy for immunocompromised patients.
Phenotypic and functional characterization of mesenchymal stromal cells isolated from pediatric patients with severe idiopathic nephrotic syndrome.
Adoptive cancer immunotherapy using DNA-demethylated T helper cells as antigen-presenting cells.
Mechanisms underlying the lack of endogenous processing and CLIP-mediated binding of the invariant chain by HLA-DP(84Gly).
Sensitive and frequent identification of high avidity neo-epitope specific CD8 (+) T cells in immunotherapy-naive ovarian cancer.
Donor-specific hypo-responsiveness occurs in simultaneous liver-kidney transplant recipients after the first year.
A hypothesis for the existence of two types of tuberculosis, reflecting two distinct types of immune failure to control the pathogen, based upon prevalence of mycobacterium-specific IgG subclasses.
Quantitative T-cell repertoire analysis of peripheral blood mononuclear cells from lung cancer patients following long-term cancer peptide vaccination.
Human T cell responses to Dengue and Zika virus infection compared to Dengue/Zika coinfection.
HLA mismatches that are identical for the antigen recognition domain are less immunogenic.
Identification of HLA-A2-restricted immunogenic peptides derived from Vitamin D-Binding Protein.
Immune recognition of somatic mutations leading to complete durable regression in metastatic breast cancer.
Reversibility of peripheral blood leukocyte phenotypic and functional changes after exposure to and withdrawal from tofacitinib, a Janus kinase inhibitor, in healthy volunteers.
Baseline immune profile by CyTOF can predict response to an investigational adjuvanted vaccine in elderly adults.
Human Leukocyte Antigen-A Allele Distribution in Nasopharyngeal Carcinoma Patients Showing Anti-Melanoma-Associated Antigen A or Synovial Sarcoma X-2 T Cell Response in Blood.
Up-Regulation of T-Cell Activation MicroRNAs in Drug-Specific CD4(+) T-Cells from Hypersensitive Patients.
Variation at Extra-epitopic Amino Acid Residues Influences Suppression of Influenza Virus Replication by M1(58-66) Epitope-Specific CD8(+) T Lymphocytes.
Validation of a CD1b tetramer assay for studies of human mycobacterial infection or vaccination.
Cytokine Networks and Survivin Peptide-Specific Cellular Immune Responses Predict Improved Survival in Patients With Glioblastoma Multiforme.
Survivin-peptide vaccination elicits immune response after allogeneic nonmyeloablative transplantation: a safe strategy to enhance the graft versus tumor effect.
The Combined Utility of Ex Vivo IFN-γ Release Enzyme-Linked ImmunoSpot Assay and In Vivo Skin Testing in Patients with Antibiotic-Associated Severe Cutaneous Adverse Reactions.
Epstein-Barr virus- and cytomegalovirus-specific immune response in patients with brain cancer.
CD8(+) T cells specific for conserved, cross-reactive Gag epitopes with strong ability to suppress HIV-1 replication.
Co-expression of CD39 and CD103 identifies tumor-reactive CD8 T cells in human solid tumors.
Induction of Cross-Clade Antibody and T-Cell Responses by a Modified Vaccinia Virus Ankara-Based Influenza A(H5N1) Vaccine in a Randomized Phase 1/2a Clinical Trial.
IFN-γ, CXCL16, uPAR: potential biomarkers for systemic lupus erythematosus.
Safety and Long-Term Efficacy of AAV4 Gene Therapy in Patients with RPE65 Leber Congenital Amaurosis.
Personalized adoptive immunotherapy for patients with EBV-associated tumors and complications: Evaluation of novel naturally processed and presented EBV-derived T-cell epitopes.
A phase I vaccination study with dendritic cells loaded with NY-ESO-1 and α-galactosylceramide: induction of polyfunctional T cells in high-risk melanoma patients.
Sensitive detection of rare antigen-specific T cells directed against Wilms' tumor 1 by FluoroSpot assay.
Intradermal HIV-1 DNA Immunization Using Needle-Free Zetajet Injection Followed by HIV-Modified Vaccinia Virus Ankara Vaccination Is Safe and Immunogenic in Mozambican Young Adults: A Phase I Randomized Controlled Trial.
Efficacy of intracellular immune checkpoint-silenced DC vaccine.
Hematopoiesis by iPSC-derived hematopoietic stem cells of aplastic anemia that escape cytotoxic T-cell attack.
Increased interferon-mediated immunity following in vitro and in vivo Modafinil treatment on peripheral immune cells.
Effective screening of T cells recognizing neoantigens and construction of T-cell receptor-engineered T cells.
Extracellular Lactate: A Novel Measure of T Cell Proliferation.
In Situ Gluten-Chitosan Interlocked Self-Assembled Supramolecular Architecture Reduces T-Cell-Mediated Immune Response to Gluten in Celiac Disease.
Regulatory T cell abundance and activation status before and after priming with HIVIS-DNA and boosting with MVA-HIV/rgp140/GLA-AF may impact the magnitude of the vaccine-induced immune responses.
The effect of lipopolysaccharide on anti-inflammatory and pro-inflammatory cytokines production of human amniotic epithelial cells.
Immunogenic particles with a broad antigenic spectrum stimulate cytolytic T cells and offer increased protection against EBV infection ex vivo and in mice.
Deep learning using tumor HLA peptide mass spectrometry datasets improves neoantigen identification.
Suppression of antitumor T cell immunity by the oncometabolite (R)-2-hydroxyglutarate.
CMV-infected kidney grafts drive the expansion of blood-borne CMV-specific T cells restricted by shared class I HLA molecules via presentation on donor cells.
Potential role of extracellular vesicle-mediated antigen presentation in Helicobacter pylori hypersensitivity during eradication therapy.
A Diverse Lipid Antigen-Specific TCR Repertoire Is Clonally Expanded during Active Tuberculosis.
Epstein-Barr virus strain heterogeneity impairs human T-cell immunity.
An Enzyme-Linked Immunosorbent Spot Assay Measuring Borrelia burgdorferi B31-Specific Interferon Gamma-Secreting T Cells Cannot Discriminate Active Lyme Neuroborreliosis from Past Lyme Borreliosis: a Prospective Study in the Netherlands.
WT1-pulsed Dendritic Cell Vaccine Combined with Chemotherapy for Resected Pancreatic Cancer in a Phase I Study.
Assessment of Humoral, Innate, and T-Cell Immune Responses to Adeno-Associated Virus Vectors.
Adenovirus-specific T-lymphocyte efficacy in the presence of methylprednisolone: An in vitro study.
T cell autoreactivity directed toward CD1c itself rather than toward carried self lipids.
Prediction of improved survival in patients with pancreatic cancer via IL-21 enhanced detection of mesothelin epitope-reactive T-cell responses.
Persistence of memory B-cell and T-cell responses to the quadrivalent HPV vaccine in HIV-infected children.
Peptide mimic for influenza vaccination using nonnatural combinatorial chemistry.
CD1b Tetramers Identify T Cells that Recognize Natural and Synthetic Diacylated Sulfoglycolipids from Mycobacterium tuberculosis.
Impact of lenalidomide maintenance on the immune environment of multiple myeloma patients with low tumor burden after autologous stem cell transplantation.
Direct-Acting Antiviral Prophylaxis in Kidney Transplantation From Hepatitis C Virus-Infected Donors to Noninfected Recipients: An Open-Label Nonrandomized Trial.
Identification of neoepitopes recognized by tumor-infiltrating lymphocytes (TILs) from patients with glioma.
Sustained Specific and Cross-Reactive T Cell Responses to Zika and Dengue Virus NS3 in West Africa.
Cancer-associated fibroblasts induce PDL1+ neutrophils through the IL6-STAT3 pathway that foster immune suppression in hepatocellular carcinoma.
Peptide-MHC Class I Tetramers Can Fail To Detect Relevant Functional T Cell Clonotypes and Underestimate Antigen-Reactive T Cell Populations.
Latent Cytomegalovirus (CMV) Infection Does Not Detrimentally Alter T Cell Responses in the Healthy Old, But Increased Latent CMV Carriage Is Related to Expanded CMV-Specific T Cells.
A Phase 1 Human Immunodeficiency Virus Vaccine Trial for Cross-Profiling the Kinetics of Serum and Mucosal Antibody Responses to CN54gp140 Modulated by Two Homologous Prime-Boost Vaccine Regimens.
Preservation of Antigen-Specific Functions of αβ T Cells and B Cells Removed from Hematopoietic Stem Cell Transplants Suggests Their Use As an Alternative Cell Source for Advanced Manipulation and Adoptive Immunotherapy.
Mucosal-Associated Invariant T Cells Display a Poor Reconstitution and Altered Phenotype after Allogeneic Hematopoietic Stem Cell Transplantation.
Safety and Immunogenicity of Malaria Vectored Vaccines Given with Routine Expanded Program on Immunization Vaccines in Gambian Infants and Neonates: A Randomized Controlled Trial.
Global Assessment of Dengue Virus-Specific CD4(+) T Cell Responses in Dengue-Endemic Areas.
Intratumorally injected pro-inflammatory allogeneic dendritic cells as immune enhancers: a first-in-human study in unfavourable risk patients with metastatic renal cell carcinoma.
Indoleamine 2,3-dioxygenase and survivin peptide vaccine combined with temozolomide in metastatic melanoma.
Sp17 Protein Expression and Major Histocompatibility Class I and II Epitope Presentation in Diffuse Large B Cell Lymphoma Patients.
Analysis of LC3-Associated Phagocytosis and Antigen Presentation.
Single-cell profiling of dynamic cytokine secretion and the phenotype of immune cells.
An aerosol challenge model of tuberculosis in Mauritian cynomolgus macaques.
Comprehensive mapping of antigen specific T cell responses in hepatitis C virus infected patients with or without spontaneous viral clearance.
Immunodominant cytomegalovirus-specific CD8+ T-cell responses in sub-Saharan African populations.
CD1b-mycolic acid tetramers demonstrate T-cell fine specificity for mycobacterial lipid tails.
Influence of Transmitted Virus on the Host's Immune Response: A Case Study.
Mesothelin-specific Immune Responses Predict Survival of Patients With Brain Metastasis.
Strong interferon-gamma mediated cellular immunity to scrub typhus demonstrated using a novel whole cell antigen ELISpot assay in rhesus macaques and humans.
Flavonolignans Inhibit IL1-β-Induced Cross-Talk between Blood Platelets and Leukocytes.
A synthetic human cytomegalovirus pp65-IE1 fusion antigen efficiently induces and expands virus specific T cells.
Adaptive from Innate: Human IFN-γ(+)CD4(+) T Cells Can Arise Directly from CXCL8-Producing Recent Thymic Emigrants in Babies and Adults.
Enhanced stimulation of human tumor-specific T cells by dendritic cells matured in the presence of interferon-γ and multiple toll-like receptor agonists.
Circulating follicular helper T cells presented distinctively different responses toward bacterial antigens in primary biliary cholangitis.
Remnant Epitope Autoimmunity in Human Abdominal Aortic Aneurysm: A Pilot Study with Elastin Peptides.
T-cell regulation through a basic suppressive mechanism targeting low-density lipoprotein receptor-related protein 1.
Tetanus Toxoid carrier protein induced T-helper cell responses upon vaccination of middle-aged adults.
Gastric expression of IL-17A and IFNγ in Helicobacter pylori infected individuals is related to symptoms.
Genome editing for scalable production of alloantigen-free lentiviral vectors for in vivo gene therapy.
Artificial human antigen-presenting cells are superior to dendritic cells at inducing cytotoxic T-cell responses.
Interleukin 10 enhanced CD8+ T cell activity and reduced CD8(+) T cell apoptosis in patients with diffuse large B cell lymphoma.
Low-Dose Cyclophosphamide Induces Antitumor T-Cell Responses, which Associate with Survival in Metastatic Colorectal Cancer.
DNA Vaccination by Electroporation Amplifies Broadly Cross-Restricted Public TCR Clonotypes Shared with HIV Controllers.
Cytomegalovirus (CMV) Epitope-Specific CD4(+) T Cells Are Inflated in HIV(+) CMV(+) Subjects.
Multiple therapeutic peptide vaccines for patients with advanced gastric cancer.
Human papillomavirus 16 (HPV16) and HPV52 E6-specific immunity in HIV-infected adults on combination antiretroviral therapy.
Boosting of post-exposure human T-cell and B-cell recall responses in vivo by Burkholderia pseudomallei-related proteins.
Antigen delivery to dendritic cells shapes human CD4+ and CD8+ T cell memory responses to Staphylococcus aureus.
The effect of current Schistosoma mansoni infection on the immunogenicity of a candidate TB vaccine, MVA85A, in BCG-vaccinated adolescents: An open-label trial.
Smoking reduces circulating CD26(hi)CD161(hi) MAIT cells in healthy individuals and patients with multiple sclerosis.
Exploration of Biomarkers for Amoxicillin/Clavulanate-Induced Liver Injury: Multi-Omics Approaches.
Drug-specific upregulation of CD137 on CD8+ T cells aids in the diagnosis of multiple antibiotic toxic epidermal necrolysis.
Varicella vaccination elicits a humoral and cellular response in children with rheumatic diseases using immune suppressive treatment.
Boosting of Cross-Reactive and Protection-Associated T Cells in Children After Live Attenuated Influenza Vaccination.
A phase II trial of autologous dendritic cell vaccination and radiochemotherapy following fluorescence-guided surgery in newly diagnosed glioblastoma patients.
Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells.
Assessment of the Plasmodium falciparum Preerythrocytic Antigen UIS3 as a Potential Candidate for a Malaria Vaccine.
Polymorphism in programmed cell death 1 gene is strongly associated with lung and kidney allograft survival in recipients from CMV-positive donors.
Evaluation of the efficacy of a therapeutic HIV vaccine by in vitro stimulation assay.
Microwave-based treatments of wheat kernels do not abolish gluten epitopes implicated in celiac disease.
An optimized IFN-γ ELISpot assay for the sensitive and standardized monitoring of CMV protein-reactive effector cells of cell-mediated immunity.
The therapeutic HIV Env C5/gp41 vaccine candidate Vacc-C5 induces specific T cell regulation in a phase I/II clinical study.
Human Cytomegalovirus (HCMV)-Specific CD4(+) T Cells Are Polyfunctional and Can Respond to HCMV-Infected Dendritic Cells In Vitro.
Human CD4(+) T Cell Responses to an Attenuated Tetravalent Dengue Vaccine Parallel Those Induced by Natural Infection in Magnitude, HLA Restriction, and Antigen Specificity.
IFNγ enhances cytotoxic efficiency of the cytotoxic T lymphocytes against human glioma cells.
Human Effector Memory T Helper Cells Engage with Mouse Macrophages and Cause Graft-versus-Host-Like Pathology in Skin of Humanized Mice Used in a Nonclinical Immunization Study.
Therapeutic protein deimmunization by T-cell epitope removal: antigen-specific immune responses in vitro and in vivo.
Pyruvate controls the checkpoint inhibitor PD-L1 and suppresses T cell immunity.
Specific humoral and cellular immune responses in cancer patients undergoing chronic immunization with a VEGF-based therapeutic vaccine.
Spontaneous CD4(+) and CD8(+) T-cell responses directed against cancer testis antigens are present in the peripheral blood of testicular cancer patients.
Characterization of High-Avidity Cytomegalovirus-Specific T Cells with Differential Tetramer Binding Coappearing after Allogeneic Stem Cell Transplantation.
Epstein-Barr virus-specific adoptive immunotherapy for recurrent, metastatic nasopharyngeal carcinoma.
Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer.
An immunogenic personal neoantigen vaccine for patients with melanoma.
Dual non-contiguous peptide occupancy of HLA class I evoke antiviral human CD8 T cell response and form neo-epitopes with self-antigens.
Expression of CD14, IL10, and Tolerogenic Signature in Dendritic Cells Inversely Correlate with Clinical and Immunologic Response to TARP Vaccination in Prostate Cancer Patients.
Immunogenicity of tocilizumab in patients with rheumatoid arthritis.
Immunological consequences of immunization with tumor lysate vaccine and propranolol as an adjuvant: A study on cytokine profiles in breast tumor microenvironment.
Safety and immunogenicity of a live attenuated pentavalent rotavirus vaccine in HIV-exposed infants with or without HIV infection in Africa.
Protection against Plasmodium falciparum malaria by PfSPZ Vaccine.
Towards standardized automated immunomonitoring: an automated ELISpot assay for safe and parallelized functionality analysis of immune cells.
Systematic evaluation of monoclonal antibodies and immunoassays for the detection of Interferon-γ and Interleukin-2 in old and new world non-human primates.
Safety and Immunogenicity of the Recombinant Mycobacterium bovis BCG Vaccine VPM1002 in HIV-Unexposed Newborn Infants in South Africa.
Expression of specific inflammasome gene modules stratifies older individuals into two extreme clinical and immunological states.
Hepatic carcinoma-associated fibroblasts enhance immune suppression by facilitating the generation of myeloid-derived suppressor cells.
Accumulation of Pol Mutations Selected by HLA-B*52:01-C*12:02 Protective Haplotype-Restricted Cytotoxic T Lymphocytes Causes Low Plasma Viral Load Due to Low Viral Fitness of Mutant Viruses.
Phase II clinical trial using novel peptide cocktail vaccine as a postoperative adjuvant treatment for surgically resected pancreatic cancer patients.
Study on age-dependent pre-existing 2009 pandemic influenza virus T and B cell responses from Chinese population.
The state of T cells before cryopreservation: Effects on post-thaw proliferation and function.
Circulating gluten-specific FOXP3(+)CD39(+) regulatory T cells have impaired suppressive function in patients with celiac disease.
Long-lived CD8+ T cell responses following Crimean-Congo haemorrhagic fever virus infection.
Ontogeny of the B- and T-cell response in a primary Zika virus infection of a dengue-naïve individual during the 2016 outbreak in Miami, FL.
CD1a presentation of endogenous antigens by group 2 innate lymphoid cells.
Prior Dengue Virus Exposure Shapes T Cell Immunity to Zika Virus in Humans.
T-cell responses to KSHV infection: a systematic approach.
Control of HIV-1 by an HLA-B*52:01-C*12:02 Protective Haplotype.
Parity improves anti-tumor immunity in breast cancer patients.
Three-Year Durability of Immune Responses Induced by HIV-DNA and HIV-Modified Vaccinia Virus Ankara and Effect of a Late HIV-Modified Vaccinia Virus Ankara Boost in Tanzanian Volunteers.
Anti-HERV-K (HML-2) capsid antibody responses in HIV elite controllers.
Intratumoral injection of IFN-β induces chemokine production in melanoma and augments the therapeutic efficacy of anti-PD-L1 mAb.
Identification of Interleukin-27 (IL-27)/IL-27 Receptor Subunit Alpha as a Critical Immune Axis for In Vivo HIV Control.
Identification of Mycobacterial RplJ/L10 and RpsA/S1 Proteins as Novel Targets for CD4(+) T Cells.
Presentation of a Conserved Adenoviral Epitope on HLA-C*0702 Allows Evasion of Natural Killer but Not T Cell Responses.
Anti-HER2 CD4(+) T-Helper Type 1 Immune Response is Superior to Breast MRI for Assessing Response to Neoadjuvant Therapy in Patients with HER2-Positive Breast Cancer.
Immune reactivity after adenoviral-mediated aquaporin-1 cDNA transfer to human parotid glands.
Dendritic cell vaccination in combination with docetaxel for patients with metastatic castration-resistant prostate cancer: A randomized phase II study.
M1-like monocytes are a major immunological determinant of severity in previously healthy adults with life-threatening influenza.
Cryopreservation-related loss of antigen-specific IFNγ producing CD4(+) T-cells can skew immunogenicity data in vaccine trials: Lessons from a malaria vaccine trial substudy.
Twelve-year survival and immune correlates in dendritic cell-vaccinated melanoma patients.
HIV-Specific Granzyme B-Secreting but Not Gamma Interferon-Secreting T Cells Are Associated with Reduced Viral Reservoirs in Early HIV Infection.
HIV Controllers Exhibit Enhanced Frequencies of Major Histocompatibility Complex Class II Tetramer(+) Gag-Specific CD4(+) T Cells in Chronic Clade C HIV-1 Infection.
Norovirus-Specific Memory T Cell Responses in Adult Human Donors.
Immune Responses to Circulating and Vaccine Viral Strains in HIV-Infected and Uninfected Children and Youth Who Received the 2013/2014 Quadrivalent Live-Attenuated Influenza Vaccine.
Incorporation of GM-CSF or CD40L Enhances the Immunogenicity of Hantaan Virus-Like Particles.
mRNA-transfected dendritic cell vaccine in combination with metronomic cyclophosphamide as treatment for patients with advanced malignant melanoma.
Phase II/III Study of Radiofrequency Ablation Combined with Cytokine-Induced Killer Cells Treating Colorectal Liver Metastases.
Single dose denileukin diftitox does not enhance vaccine-induced T cell responses or effectively deplete Tregs in advanced melanoma: immune monitoring and clinical results of a randomized phase II trial.
Peptide vaccination against multiple myeloma using peptides derived from anti-apoptotic proteins: a phase I trial.
Broad HIV-1 inhibition in vitro by vaccine-elicited CD8(+) T cells in African adults.
Immunomodulatory Effects of 1,25-Dihydroxyvitamin D(3) on Dendritic Cells Promote Induction of T Cell Hyporesponsiveness to Myelin-Derived Antigens.
Is There Any Difference between the In Situ and Systemic IL-10 and IFN-γ Production when Clinical Forms of Cutaneous Sporotrichosis Are Compared?
Co-Expansion of Cytokine-Induced Killer Cells and Vγ9Vδ2 T Cells for CAR T-Cell Therapy.
Human Peripheral Blood Mononuclear Cell Function and Dendritic Cell Differentiation Are Affected by Bisphenol-A Exposure.
Use of In Vitro Assays to Assess Immunogenicity Risk of Antibody-Based Biotherapeutics.
Boosting with Subtype C CN54rgp140 Protein Adjuvanted with Glucopyranosyl Lipid Adjuvant after Priming with HIV-DNA and HIV-MVA Is Safe and Enhances Immune Responses: A Phase I Trial.
Recombinant Dengue 2 Virus NS3 Helicase Protein Enhances Antibody and T-Cell Response of Purified Inactivated Vaccine.
Mucorales-Specific T Cells in Patients with Hematologic Malignancies.
Identification of Immunogenic Cytotoxic T Lymphocyte Epitopes Containing Drug Resistance Mutations in Antiretroviral Treatment-Naïve HIV-Infected Individuals.
Prediction of T Cell Epitopes from Leishmania major Potentially Excreted/Secreted Proteins Inducing Granzyme B Production.
Identification of Novel HLA-A*24:02-Restricted Epitope Derived from a Homeobox Protein Expressed in Hematological Malignancies.
Human cytomegalovirus miR-UL112-1 promotes the down-regulation of viral immediate early-gene expression during latency to prevent T-cell recognition of latently infected cells.
Epitope Mapping of Neutralizing Monoclonal Antibodies to Human Interferon-γ Using Human-Bovine Interferon-γ Chimeras.
Identification of HLA-A*11:01-restricted Mycobacterium tuberculosis CD8(+) T cell epitopes.
Structural characterization of the lipid A from the LPS of the haloalkaliphilic bacterium Halomonas pantelleriensis.
Combination treatment with decitabine and ionizing radiation enhances tumor cells susceptibility of T cells.
Adjuvanted multi-epitope vaccines protect HLA-A*11:01 transgenic mice against Toxoplasma gondii.
Epstein-Barr viral miRNAs inhibit antiviral CD4+ T cell responses targeting IL-12 and peptide processing.
Abnormal thymic stromal lymphopoietin expression in the duodenal mucosa of patients with coeliac disease.
Vaccination Against Human Papilloma Viruses Leads to a Favorable Cytokine Profile of Specific T Cells.
Circulating functional T cells specific to human herpes virus 6 (HHV6) antigens in individuals with chromosomally integrated HHV6.
Comparison of Three Isolation Techniques for Human Peripheral Blood Mononuclear Cells: Cell Recovery and Viability, Population Composition, and Cell Functionality.
Defective T Memory Cell Differentiation after Varicella Zoster Vaccination in Older Individuals.
Protective Efficacy of Plasmodium vivax Radiation-Attenuated Sporozoites in Colombian Volunteers: A Randomized Controlled Trial.
Epstein-Barr virus microRNAs reduce immune surveillance by virus-specific CD8+ T cells.
Psoriatic T cells recognize neolipid antigens generated by mast cell phospholipase delivered by exosomes and presented by CD1a.
CD8(+) T cell response to human papillomavirus 16 E7 is able to predict survival outcome in oropharyngeal cancer.
Protective Role of Cross-Reactive CD8 T Cells Against Dengue Virus Infection.
The CD8⁺ T Cell-Mediated Immunity Induced by HPV-E6 Uploaded in Engineered Exosomes Is Improved by ISCOMATRIX(TM) Adjuvant.
A phase 1, randomized, controlled dose-escalation study of EP-1300 polyepitope DNA vaccine against Plasmodium falciparum malaria administered via electroporation.
Graft versus self (GvS) against T-cell autoantigens is a mechanism of graft-host interaction.
Direct identification of clinically relevant neoepitopes presented on native human melanoma tissue by mass spectrometry.
Matrix metalloproteinase-10 is a target of T and B cell responses that correlate with synovial pathology in patients with antibiotic-refractory Lyme arthritis.
Diagnosis of latent tuberculosis by ELISPOT assay and tuberculin skin test.
Immunostimulatory Activity of the Cytokine-Based Biologic, IRX-2, on Human Papillomavirus-Exposed Langerhans Cells.
Evaluating the Role of Cellular Immune Responses in the Emergence of HCV NS3 Resistance Mutations During Protease Inhibitor Therapy.
Functional cloning of a gp100-reactive T-cell receptor from vitiligo patient skin.
Phase I clinical trial of a five-peptide cancer vaccine combined with cyclophosphamide in advanced solid tumors.
Discovery of the First α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Antagonist Dependent upon Transmembrane AMPA Receptor Regulatory Protein (TARP) γ-8.
Novel HLA-A2-restricted human metapneumovirus epitopes reduce viral titers in mice and are recognized by human T cells.
The Antitumor Efficacy of IL2/IL21-Cultured Polyfunctional Neu-Specific T Cells Is TNFα/IL17 Dependent.
Mechanisms of immune escape in central nervous system infection with neurotropic JC virus variant.
T-cell libraries allow simple parallel generation of multiple peptide-specific human T-cell clones.
Markers of Protection in Children and Adolescents Six to Fourteen Years After Primary Hepatitis B Vaccination in Real Life: A Pilot Study.
CD4(+) and CD8(+) TCRβ repertoires possess different potentials to generate extraordinarily high-avidity T cells.
Enhanced Cytotoxic CD8 T Cell Priming Using Dendritic Cell-Expressing Human Papillomavirus-16 E6/E7-p16INK4 Fusion Protein with Sequenced Anti-Programmed Death-1.
Transgenic antigen-specific, HLA-A*02:01-allo-restricted cytotoxic T cells recognize tumor-associated target antigen STEAP1 with high specificity.
Human CD8(+) T Cells Target Multiple Epitopes in Respiratory Syncytial Virus Polymerase.
Reconstitution of cytomegalovirus-specific T-cell response in allogeneic hematopoietic stem cell recipients: the contribution of six frequently recognized, virus-encoded ORFs.
Effect of mTORC1/mTORC2 inhibition on T cell function: potential role in graft-versus-host disease control.
Aberrant Glycosylation of Anchor-Optimized MUC1 Peptides Can Enhance Antigen Binding Affinity and Reverse Tolerance to Cytotoxic T Lymphocytes.
Human T cell responses to Japanese encephalitis virus in health and disease.
Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy.
Serotype-Specific Cell-Mediated Immunity Associated With Clearance of Homotypic Group B Streptococcus Rectovaginal Colonization in Pregnant Women.
Validation of an IFNγ/IL2 FluoroSpot assay for clinical trial monitoring.
Multiple T-cell responses are associated with better control of acute HIV-1 infection: An observational study.
PD-L1-specific T cells.
Granulocyte colony-stimulating factor impairs CD8(+) T cell functionality by interfering with central activation elements.
A Quantitative Analysis of Complexity of Human Pathogen-Specific CD4 T Cell Responses in Healthy M. tuberculosis Infected South Africans.
In vitro rapid diagnostic tests for severe drug hypersensitivity reactions in children.
A Longitudinal Hepatitis B Vaccine Cohort Demonstrates Long-lasting Hepatitis B Virus (HBV) Cellular Immunity Despite Loss of Antibody Against HBV Surface Antigen.
Transcriptional Profiling of Th2 Cells Identifies Pathogenic Features Associated with Asthma.
MiR-381-3p Regulates the Antigen-Presenting Capability of Dendritic Cells and Represses Antituberculosis Cellular Immune Responses by Targeting CD1c.
Adjuvant Immunotherapy to Improve Outcome in High-Risk Pediatric Sarcomas.
Elevated and cross-responsive CD1a-reactive T cells in bee and wasp venom allergic individuals.
Characteristics of immune memory 10-15 years after primary hepatitis B vaccination.
Human autoreactive T cells recognize CD1b and phospholipids.
The Tumor Antigen NY-ESO-1 Mediates Direct Recognition of Melanoma Cells by CD4+ T Cells after Intercellular Antigen Transfer.
Monocyte Stabilin-1 Suppresses the Activation of Th1 Lymphocytes.
Population tailored modification of tuberculosis specific interferon-gamma release assay.
Immunoregulatory effects on T lymphocytes by human mesenchymal stromal cells isolated from bone marrow, amniotic fluid, and placenta.
Human Wharton's jelly-derived mesenchymal stromal cells engineered to secrete Epstein-Barr virus interleukin-10 show enhanced immunosuppressive properties.
Chronic and recurrent benign lymphadenopathy without constitutional symptoms associated with human herpesvirus-6B reactivation.
Reduced naïve CD8(+) T-cell priming efficacy in elderly adults.
Expansion of Tumor-reactive T Cells From Patients With Pancreatic Cancer.
CD46 Activation Regulates miR-150-Mediated Control of GLUT1 Expression and Cytokine Secretion in Human CD4+ T Cells.
Filaggrin inhibits generation of CD1a neolipid antigens by house dust mite-derived phospholipase.
Effect of Depot Medoxyprogesterone Acetate on Immune Functions and Inflammatory Markers of HIV-Infected Women.
Measurement of ex vivo ELISpot interferon-gamma recall responses to Plasmodium falciparum AMA1 and CSP in Ghanaian adults with natural exposure to malaria.
Phase I/II trial of combination of temozolomide chemotherapy and immunotherapy with fusions of dendritic and glioma cells in patients with glioblastoma.
Human parainfluenza virus-3 can be targeted by rapidly ex vivo expanded T lymphocytes.
Detection of Primary T Cell Responses to Drugs and Chemicals in HLA-Typed Volunteers: Implications for the Prediction of Drug Immunogenicity.
Toward Optimal Cryopreservation and Storage for Achievement of High Cell Recovery and Maintenance of Cell Viability and T Cell Functionality.
Cytomegalovirus-Specific IL-10-Producing CD4+ T Cells Are Governed by Type-I IFN-Induced IL-27 and Promote Virus Persistence.
An escalating dose study to assess the safety, tolerability and immunogenicity of a Herpes Simplex Virus DNA vaccine, COR-1.
A functional polymorphism in the NKG2D gene modulates NK-cell cytotoxicity and is associated with susceptibility to Human Papilloma Virus-related cancers.
Processing and MHC class II presentation of exogenous soluble antigen involving a proteasome-dependent cytosolic pathway in CD40-activated B cells.
Establishment and characterization of a highly immunogenic human renal carcinoma cell line.
Expanded lung T-bet+RORγT+ CD4+ T-cells in sarcoidosis patients with a favourable disease phenotype.
A statistical approach to determining responses to individual peptides from pooled-peptide ELISpot data.
Identification of proteins derived from Listeria monocytogenes inducing human dendritic cell maturation.
Safety, immune and clinical responses in metastatic melanoma patients vaccinated with a long peptide derived from indoleamine 2,3-dioxygenase in combination with ipilimumab.
Human TRAV1-2-negative MR1-restricted T cells detect S. pyogenes and alternatives to MAIT riboflavin-based antigens.
Development of an IFNγ ELISPOT for the analysis of the human T cell response against mumps virus.
Analysis of HIV-1c-Specific CTL Responses with HIV-1 Reservoir Size and Forms.
Cellular Interferon Gamma and Granzyme B Responses to Cytomegalovirus-pp65 and Influenza N1 Are Positively Associated in Elderly.
Dendritic-tumor cell hybrids induce tumor-specific immune responses more effectively than the simple mixture of dendritic and tumor cells.
Higher numbers of memory B-cells and Th2-cytokine skewing in high responders to hepatitis B vaccination.
Dasatinib inhibits HIV-1 replication through the interference of SAMHD1 phosphorylation in CD4+ T cells.
T-cell activation is an immune correlate of risk in BCG vaccinated infants.
A Diverse Repertoire of CD4 T Cells Targets the Immediate-Early 1 Protein of Human Cytomegalovirus.
Boosted Influenza-Specific T Cell Responses after H5N1 Pandemic Live Attenuated Influenza Virus Vaccination.
The immunological footprint of CMV in HIV-1 patients stable on long-term ART.
Pre-Vaccination Frequencies of Th17 Cells Correlate with Vaccine-Induced T-Cell Responses to Survivin-Derived Peptide Epitopes.
Study of the BCG Vaccine-Induced Cellular Immune Response in Schoolchildren in Antananarivo, Madagascar.
Anti-hepatitis C virus T-cell immunity in the context of multiple exposures to the virus.
The use of wavelength modulated Raman spectroscopy in label-free identification of T lymphocyte subsets, natural killer cells and dendritic cells.
Determinants of vaccine immunogenicity in HIV-infected pregnant women: analysis of B and T cell responses to pandemic H1N1 monovalent vaccine.
Viral infection of human lung macrophages increases PDL1 expression via IFNβ.
Abacavir-reactive memory T cells are present in drug naïve individuals.
Spontaneous Immunity Against the Receptor Tyrosine Kinase ROR1 in Patients with Chronic Lymphocytic Leukemia.
Ratite oils promote keratinocyte cell growth and inhibit leukocyte activation.
Phase I/II study of adjuvant immunotherapy with sentinel lymph node T lymphocytes in patients with colorectal cancer.
Characterization of amoxicillin- and clavulanic acid-specific T cells in patients with amoxicillin-clavulanate-induced liver injury.
Integration of humoral and cellular HLA-specific immune responses in cord blood allograft rejection.
T-Regulatory Cells and Inflammatory and Inhibitory Cytokines in Malawian Children Residing in an Area of High and an Area of Low Malaria Transmission During Acute Uncomplicated Malaria and in Convalescence.
Thrombin may modulate dendritic cell activation in kidney transplant recipients with delayed graft function.
Exome Sequencing to Predict Neoantigens in Melanoma.
IL-35 inhibits HBV antigen-specific IFN-γ-producing CTLs in vitro.
The antigenic landscape of multiple myeloma: mass spectrometry (re)defines targets for T-cell-based immunotherapy.
Immune Reconstitution After Allogeneic Hematopoietic Stem Cell Transplantation and Association With Occurrence and Outcome of Invasive Aspergillosis.
Role of the 2B4 Receptor in CD8+ T-Cell-Dependent Immune Control of Epstein-Barr Virus Infection in Mice With Reconstituted Human Immune System Components.
T-Cell Responses Are Associated with Survival in Acute Melioidosis Patients.
Innate Immune Activity Correlates with CD4 T Cell-Associated HIV-1 DNA Decline during Latency-Reversing Treatment with Panobinostat.
Therapeutic bispecific T-cell engager antibody targeting the intracellular oncoprotein WT1.
Investigation of inflammatory profile in MSUD patients: benefit of L-carnitine supplementation.
Heteroclitic Peptides Increase Proliferation and Reduce Evidence of Human Immunodeficiency Virus-Specific CD8⁺ T Cell Dysfunction.
AZ17: a new bispecific drug targeting IL-6 and IL-23 with potential clinical use--improves psoriasis in a human xenograft transplantation model.
Annexin A2 is a target of autoimmune T and B cell responses associated with synovial fibroblast proliferation in patients with antibiotic-refractory Lyme arthritis.
In Vitro Priming of Naı̈ve T-cells with p-Phenylenediamine and Bandrowski's Base.
Zoster Vaccination Increases the Breadth of CD4+ T Cells Responsive to Varicella Zoster Virus.
Gut commensal microbes do not represent a dominant antigenic source for continuous CD4+ T-cell activation during HIV-1 infection.
Cytomegalovirus Encephalitis in a Patient with Severe Combined Immunodeficiency.
Long-term control of diabetes in immunosuppressed nonhuman primates (NHP) by the transplantation of adult porcine islets.
Identification of novel Lck-derived T helper epitope long peptides applicable for HLA-A2(+) cancer patients as cancer vaccine.
Identification of novel Mycobacterium tuberculosis CD4 T-cell antigens via high throughput proteome screening.
Transmitted/Founder Viruses Rapidly Escape from CD8+ T Cell Responses in Acute Hepatitis C Virus Infection.
Clinical Control of HIV-1 by Cytotoxic T Cells Specific for Multiple Conserved Epitopes.
Th22 cells increase in poor prognosis multiple myeloma and promote tumor cell growth and survival.
Transitional B lymphocytes are associated with protection from kidney allograft rejection: a prospective study.
Antibody and T-cell responses associated with experimental human malaria infection or vaccination show limited relationships.
Anti-HER2 CD4(+) T-helper type 1 response is a novel immune correlate to pathologic response following neoadjuvant therapy in HER2-positive breast cancer.
Tumor-infiltrating lymphocyte activity is enhanced in tumors with low IL-10 production in HBV-induced hepatocellular carcinoma.
Longevity of B-cell and T-cell responses after live attenuated influenza vaccination in children.
T Cell Immunity to the Alkyl Hydroperoxide Reductase of Burkholderia pseudomallei: A Correlate of Disease Outcome in Acute Melioidosis.
Complete regression of metastatic cervical cancer after treatment with human papillomavirus-targeted tumor-infiltrating T cells.
Mapping the HLA ligandome landscape of acute myeloid leukemia: a targeted approach toward peptide-based immunotherapy.
Safety and tolerability of allogeneic dendritic cell vaccination with induction of Wilms tumor 1-specific T cells in a pediatric donor and pediatric patient with relapsed leukemia: a case report and review of the literature.
Alternative effector-function profiling identifies broad HIV-specific T-cell responses in highly HIV-exposed individuals who remain uninfected.
Early Kinetics of the HLA Class I-Associated Peptidome of MVA.HIVconsv-Infected Cells.
Differences in immune responses between CMV-seronegative and -seropositive patients with myocardial ischemia and reperfusion.
Kinetics and Immunodominance of Virus-Specific T Cell Responses During Hantaan Virus Infection.
Aging influences the response of T cells to stimulation by the ellagitannin, oenothein B.
Maternal plasma and breastmilk viral loads are associated with HIV-1-specific cellular immune responses among HIV-1-exposed, uninfected infants in Kenya.
Gastrointestinal immunity against tryptophan hydroxylase-1, aromatic L-amino-acid decarboxylase, AIE-75, villin and Paneth cells in APECED.
Generation of TCR-engineered T cells and their use to control the performance of T cell assays.
WT1 vaccination in AML and MDS: A pilot trial with synthetic analog peptides.
The Epstein-Barr Virus Lytic Protein BZLF1 as a Candidate Target Antigen for Vaccine Development.
Generation of tumor-specific cytotoxic T-lymphocytes from the peripheral blood of colorectal cancer patients for adoptive T-cell transfer.
A Synthetic Influenza Virus Vaccine Induces a Cellular Immune Response That Correlates with Reduction in Symptomatology and Virus Shedding in a Randomized Phase Ib Live-Virus Challenge in Humans.
Mycobacterium bovis BCG Vaccination Induces Divergent Proinflammatory or Regulatory T Cell Responses in Adults.
Bifidobacteria Enhance Antigen Sampling and Processing by Dendritic Cells in Pediatric Inflammatory Bowel Disease.
Identification of autoreactive CD8+ T cell responses targeting chromogranin A in humanized NOD mice and type 1 diabetes patients.
Detection of HIV-1-specific T-cell immune responses in highly HIV-exposed uninfected individuals by in-vitro dendritic cell co-culture.
T cell epitope clustering in the highly immunogenic BZLF1 antigen of Epstein-Barr virus.
Ingestion of oats and barley in patients with celiac disease mobilizes cross-reactive T cells activated by avenin peptides and immuno-dominant hordein peptides.
Cellular immune response following pre-exposure and postexposure rabies vaccination by intradermal and intramuscular routes.
Immunity to the vacuolar ATPase complex accessory unit ATP6S1 in patients with malignant melanoma.
Reactivity against microsatellite instability-induced frameshift mutations in patients with inflammatory bowel disease.
Myocardial ischemia and reperfusion leads to transient CD8 immune deficiency and accelerated immunosenescence in CMV-seropositive patients.
Phase II clinical trial of multiple peptide vaccination for advanced head and neck cancer patients revealed induction of immune responses and improved OS.
Identification of promiscuous HPV16-derived T helper cell epitopes for therapeutic HPV vaccine design.
Characterisation of the cytokine milieu associated with the up-regulation of IL-6 and suppressor of cytokine 3 in chronic hepatitis C treatment non-responders.
Broadly-specific cytotoxic T cells targeting multiple HIV antigens are expanded from HIV+ patients: implications for immunotherapy.
Effects of antiviral therapy on the cellular immune response in patients with chronic hepatitis B.
Bee venom processes human skin lipids for presentation by CD1a.
Safety and immunogenicity of DNA vaccines encoding Ebolavirus and Marburgvirus wild-type glycoproteins in a phase I clinical trial.
A side-by-side comparison of T cell reactivity to fifty-nine Mycobacterium tuberculosis antigens in diverse populations from five continents.
T- and B-cell responses and previous exposure to hepatitis B virus in 'anti-HBc alone' patients.
Recombinant Immunotoxin with T-cell Epitope Mutations That Greatly Reduce Immunogenicity for Treatment of Mesothelin-Expressing Tumors.
Melanocyte antigen triggers autoimmunity in human psoriasis.
A Highly Expressed Human Protein, Apolipoprotein B-100, Serves as an Autoantigen in a Subgroup of Patients With Lyme Disease.
Human papillomavirus-exposed Langerhans cells are activated by stabilized Poly-I:C.
Immune responses to latent tuberculosis antigen Rv2659c in Chinese populations.
Oral administration of non-absorbable delayed release 6-mercaptopurine is locally active in the gut, exerts a systemic immune effect and alleviates Crohn's disease with low rate of side effects: results of double blind Phase II clinical trial.
Cross-Reactivity Between Influenza Matrix- and HIV-1 P17-Specific CTL-A Large Cohort Study.
The Tumor Antigen Cyclin B1 Hosts Multiple CD4 T Cell Epitopes Differently Recognized by Pre-Existing Naive and Memory Cells in Both Healthy and Cancer Donors.
Langerhans Cell-Dendritic Cell Cross-Talk via Langerin and Hyaluronic Acid Mediates Antigen Transfer and Cross-Presentation of HIV-1.
IL-15 induces strong but short-lived tumor-infiltrating CD8 T cell responses through the regulation of Tim-3 in breast cancer.
Functionality of dengue virus specific memory T cell responses in individuals who were hospitalized or who had mild or subclinical dengue infection.
A high-throughput RNAi screen for detection of immune-checkpoint molecules that mediate tumor resistance to cytotoxic T lymphocytes.
Cytokine-induced killer cells engineered with exogenous T-cell receptors directed against melanoma antigens: enhanced efficacy of effector cells endowed with a double mechanism of tumor recognition.
Antigen-induced regulation of T-cell motility, interaction with antigen-presenting cells and activation through endogenous thrombospondin-1 and its receptors.
Assessing the prognostic value of preoperative carcinoembryonic antigen-specific T-cell responses in colorectal cancer.
Optimal PEGylation can improve the exposure of interferon in the lungs following pulmonary administration.
Correction: Santos, R.S., et al. Improvement of IFNγ ELISPOT Performance Following Overnight Resting of Frozen PBMC Samples Confirmed Through Rigorous Statistical Analysis. Cells 2015, 4, 1-18.
Analysis of protein kinase C theta inhibitors for the control of HIV-1 replication in human CD4+ T cells reveals an effect on retrotranscription in addition to viral transcription.
Association of antigen-specific T-cell responses with antigen expression and immunoparalysis in multiple myeloma.
Incomplete recovery of pneumococcal CD4 T cell immunity after initiation of antiretroviral therapy in HIV-infected malawian adults.
Novel approach to activity evaluation for release-active forms of anti-interferon-gamma antibodies based on enzyme-linked immunoassay.
Identification and HLA-tetramer-validation of human CD4+ and CD8+ T cell responses against HCMV proteins IE1 and IE2.
The effect of maternal helminth infection on maternal and neonatal immune function and immunity to tuberculosis.
The candidate TB vaccine, MVA85A, induces highly durable Th1 responses.
Safety and comparability of controlled human Plasmodium falciparum infection by mosquito bite in malaria-naïve subjects at a new facility for sporozoite challenge.
Neonatal BCG vaccination is associated with enhanced T-helper 1 immune responses to heterologous infant vaccines.
The effect of in vivo exposure to zearalenone on cytokine secretion by Th1 and Th2 lymphocytes in porcine Peyer's patches after in vitro stimulation with LPS.
Greater frequency of CD5-negative CD8(+) T cells against human immunodeficiency virus type 1 than other viruses is consistent with adaptation to antigenic variation.
Cell-mediated immune responses to respiratory syncytial virus infection: magnitude, kinetics, and correlates with morbidity and age.
Clinical validation of IFNγ/IL-10 and IFNγ/IL-2 FluoroSpot assays for the detection of Tr1 T cells and influenza vaccine monitoring in humans.
A Human Papillomavirus Type 16 E6 52-62 CD4 T-Cell Epitope Restricted by the HLA-DR11 Molecule Described in an Epitope Hotspot.
Involvement of PIT-1-reactive cytotoxic T lymphocytes in anti-PIT-1 antibody syndrome.
Telomerase (GV1001) vaccination together with gemcitabine in advanced pancreatic cancer patients.
Acute respiratory failure secondary to eosinophilic pneumonia following influenza vaccination in an elderly man with chronic obstructive pulmonary disease.
Nanogel-based immunologically stealth vaccine targets macrophages in the medulla of lymph node and induces potent antitumor immunity.
High frequency of cytolytic 21-hydroxylase-specific CD8+ T cells in autoimmune Addison's disease patients.
The cytokine production of peripheral blood mononuclear cells reflects the autoantibody profile of patients suffering from type 1 diabetes.
Common Ewing sarcoma-associated antigens fail to induce natural T cell responses in both patients and healthy individuals.
Protection against hepatitis C infection via NK cells in highly-exposed uninfected injecting drug users.
Early initiation of combination antiretroviral therapy in HIV-1-infected newborns can achieve sustained virologic suppression with low frequency of CD4+ T cells carrying HIV in peripheral blood.
Blood dendritic cell levels associated with impaired IL-12 production and T-cell deficiency in patients with kidney disease: implications for post-transplant viral infections.
Dynamics of T-cell IFN-γ and miR-29a expression during active pulmonary tuberculosis.
Hydrogen peroxide inactivation of influenza virus preserves antigenic structure and immunogenicity.
Health maintenance and inflammatory bowel disease.
Identification and translational validation of novel mammaglobin-A CD8 T cell epitopes.
Oral vaccination against HPV E7 for treatment of cervical intraepithelial neoplasia grade 3 (CIN3) elicits E7-specific mucosal immunity in the cervix of CIN3 patients.
Altered cellular and humoral immunity to varicella-zoster virus in patients with autoimmune diseases.
Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens.
Triple Cytokine FluoroSpot Analysis of Human Antigen-Specific IFN-γ, IL-17A and IL-22 Responses.
Microvescicles derived from mesenchymal stromal cells are not as effective as their cellular counterpart in the ability to modulate immune responses in vitro.
P53, hTERT, WT-1, and VEGFR2 are the most suitable targets for cancer vaccine therapy in HLA-A24 positive pancreatic adenocarcinoma.
First-in-man clinical results with good manufacturing practice (GMP)-compliant polypeptide-expanded adenovirus-specific T cells after haploidentical hematopoietic stem cell transplantation.
Results of a randomized phase I gene therapy clinical trial of nononcolytic fowlpox viruses encoding T cell costimulatory molecules.
Enzyme-linked immunospot assay for detection of human respiratory syncytial virus f protein-specific gamma interferon-producing T cells.
Engineering human peripheral blood stem cell grafts that are depleted of naïve T cells and retain functional pathogen-specific memory T cells.
Raltegravir and elvitegravir-resistance mutation E92Q affects HLA-B*40:02-restricted HIV-1-specific CTL recognition.
Dominant CD4-dependent RNA-dependent RNA polymerase-specific T-cell responses in children acutely infected with human enterovirus 71 and healthy adult controls.
Switching and emergence of CTL epitopes in HIV-1 infection.
The human immune system recognizes neopeptides derived from mitochondrial DNA deletions.
TCR bias and affinity define two compartments of the CD1b-glycolipid-specific T Cell repertoire.
Broad and potent cellular and humoral immune responses after a second late HIV-modified vaccinia virus ankara vaccination in HIV-DNA-primed and HIV-modified vaccinia virus Ankara-boosted Swedish vaccinees.
Immunological and antiviral responses after therapeutic DNA immunization in chronic hepatitis B patients efficiently treated by analogues.
Enhancement of Immune Responses by Co-delivery of CCL19/MIP-3beta Chemokine Plasmid With HCV Core DNA/Protein Immunization.
Universal cytotoxic activity of a HTLV-1 Tax-specific T cell clone from an HLA-A*24:02⁺ patient with adult T-cell leukemia against a variety of HTLV-I-infected T-cells.
Phase I clinical trial of multiple-peptide vaccination for patients with advanced biliary tract cancer.
Immunogenicity of ALVAC-HIV vCP1521 in infants of HIV-1-infected women in Uganda (HPTN 027): the first pediatric HIV vaccine trial in Africa.
Frequent occurrence of cytomegalovirus retinitis during immune reconstitution warrants regular ophthalmic screening in high-risk pediatric allogeneic hematopoietic stem cell transplant recipients.
IGRA-positive patients and interferon-gamma/interleukin-2 signatures: can the Fluorospot assay provide further information?
Clinical trial of a 7-peptide cocktail vaccine with oral chemotherapy for patients with metastatic colorectal cancer.
Submicroscopic infections with Plasmodium falciparum during pregnancy and their association with circulating cytokine, chemokine, and cellular profiles.
Adjuvant effects of aluminium hydroxide-adsorbed allergens and allergoids - differences in vivo and in vitro.
Viable mononuclear cell stability study for implementation in a proficiency testing program: impact of shipment conditions.
CD8 T cell-evasive functions of human cytomegalovirus display pervasive MHC allele specificity, complementarity, and cooperativity.
Induction of Gag-specific CD4 T cell responses during acute HIV infection is associated with improved viral control.
Statistical methods for the assessment of EQAPOL proficiency testing: ELISpot, Luminex, and Flow Cytometry.
The External Quality Assurance Oversight Laboratory (EQAPOL) proficiency program for IFN-gamma enzyme-linked immunospot (IFN-γ ELISpot) assay.
Establishment and maintenance of a PBMC repository for functional cellular studies in support of clinical vaccine trials.
Identification of host and viral factors involved in a dissimilar resolution of a hepatitis C virus infection.
Differential T-cell responses of semi-immune and susceptible malaria subjects to in silico predicted and synthetic peptides of Plasmodium falciparum.
Immunotherapy with an HIV-DNA Vaccine in Children and Adults.
Efficient identification of mutated cancer antigens recognized by T cells associated with durable tumor regressions.
T cell response to alpha crystallin and Mycobacterium tuberculosis specific antigens using ex-vivo elispot assay for detecting latent tuberculosis infection in Addis Ababa, Ethiopia.
Immunoprevalence and immunodominance of HLA-Cw*0801-restricted T cell response targeting the hepatitis B virus envelope transmembrane region.
Brucella melitensis T cell epitope recognition in humans with brucellosis in Peru.
A phase I clinical trial of vaccination with KIF20A-derived peptide in combination with gemcitabine for patients with advanced pancreatic cancer.
Combination of Epstein-Barr virus nuclear antigen 1, 3 and lytic antigen BZLF1 peptide pools allows fast and efficient stimulation of Epstein-Barr virus-specific T cells for adoptive immunotherapy.
Detection of HCV-Specific IFN-γ Responses in HCV Antibody and HCV RNA Negative Injecting Drug Users.
Anti-melanoma activity of T cells redirected with a TCR-like chimeric antigen receptor.
Systemic treatment with CAR-engineered T cells against PSCA delays subcutaneous tumor growth and prolongs survival of mice.
Memory CD8(+) T cells elicited by HIV-1 lipopeptide vaccines display similar phenotypic profiles but differences in term of magnitude and multifunctionality compared with FLU- or EBV-specific memory T cells in humans.
Susceptibility to CD8 T-cell-mediated killing influences the reservoir of latently HIV-1-infected CD4 T cells.
Long-lasting disease stabilization in the absence of toxicity in metastatic lung cancer patients vaccinated with an epitope derived from indoleamine 2,3 dioxygenase.
Human cytotoxic T lymphocytes directed to seasonal influenza A viruses cross-react with the newly emerging H7N9 virus.
Interferon-gamma ELISPOT detecting reactivity of T cells to TSH receptor peptides in Graves' disease.
Pre-eclampsia affects cord blood NK cell expression of activation receptors and serum cytokine levels but not CB monocyte characteristics.
Adoptive immunotherapy with antigen-specific T cells during extracorporeal membrane oxygenation (ECMO) for adenovirus-related respiratory failure in a child given haploidentical stem cell transplantation.
Vaccine-elicited human T cells recognizing conserved protein regions inhibit HIV-1.
Ex-vivo whole blood secretion of interferon (IFN)-γ and IFN-γ-inducible protein-10 measured by enzyme-linked immunosorbent assay are as sensitive as IFN-γ enzyme-linked immunospot for the detection of gluten-reactive T cells in human leucocyte antigen (HLA)-DQ2·5(+) -associated coeliac disease.
The immunological and clinical effects of mutated ras peptide vaccine in combination with IL-2, GM-CSF, or both in patients with solid tumors.
CD8+ T cells are activated in an antigen-independent manner in HIV-infected individuals.
Gap junction intercellular communications regulate NK cell activation and modulate NK cytotoxic capacity.
High IP-10 levels decrease T cell function in HIV-1-infected individuals on ART.
A registry of HLA-typed donors for production of virus-specific CD4 and CD8 T lymphocytes for adoptive reconstitution of immune-compromised patients.
Seasonal influenza vaccination is the strongest correlate of cross-reactive antibody responses in migratory bird handlers.
Pre-immature dendritic cells (PIDC) pulsed with HPV16 E6 or E7 peptide are capable of eliciting specific immune response in patients with advanced cervical cancer.
Chemoradiotherapy-induced upregulation of PD-1 antagonizes immunity to HPV-related oropharyngeal cancer.
Experimental evidence that mutated-self peptides derived from mitochondrial DNA somatic mutations have the potential to trigger autoimmunity.
Mesenchymal stromal cell therapy is associated with increased adenovirus-associated but not cytomegalovirus-associated mortality in children with severe acute graft-versus-host disease.
Artificial antigen-presenting cells expressing CD80, CD70, and 4-1BB ligand efficiently expand functional T cells specific to tumor-associated antigens.
IFN-gamma and TNF associated with severe falciparum malaria infection in Saudi pregnant women.
Alpha fetoprotein DNA prime and adenovirus boost immunization of two hepatocellular cancer patients.
Phase I clinical study of multiple epitope peptide vaccine combined with chemoradiation therapy in esophageal cancer patients.
Impact of immunosuppression on recall immune responses to influenza vaccination in stable renal transplant recipients.
Specific active immunotherapy with a VEGF vaccine in patients with advanced solid tumors. results of the CENTAURO antigen dose escalation phase I clinical trial.
Highly significant antiviral activity of HIV-1 LTR-specific tre-recombinase in humanized mice.
Presentation of an immunodominant immediate-early CD8+ T cell epitope resists human cytomegalovirus immunoevasion.
Impairment of IFN-gamma response to synthetic peptides of Mycobacterium tuberculosis in a 7-day whole blood assay.
Trivalent combination vaccine induces broad heterologous immune responses to norovirus and rotavirus in mice.
Bee Venom Phospholipase A2, a Good "Chauffeur" for Delivering Tumor Antigen to the MHC I and MHC II Peptide-Loading Compartments of the Dendritic Cells: The Case of NY-ESO-1.
Two doses of candidate TB vaccine MVA85A in antiretroviral therapy (ART) naïve subjects gives comparable immunogenicity to one dose in ART+ subjects.
Virus-specific immune response in HBeAg-negative chronic hepatitis B: relationship with clinical profile and HBsAg serum levels.
Cytotoxicity of tumor antigen specific human T cells is unimpaired by arginine depletion.
Short-term in-vitro expansion improves monitoring and allows affordable generation of virus-specific T-cells against several viruses for a broad clinical application.
Use of RT-defective HIV virions: new tool to evaluate specific response in chronic asymptomatic HIV-infected individuals.
IRX-2, a novel immunotherapeutic, enhances functions of human dendritic cells.
Challenges in the development of an immunochromatographic interferon-gamma test for diagnosis of pleural tuberculosis.
Loss of multi-epitope specificity in memory CD4(+) T cell responses to B. pertussis with age.
Recall responses to tetanus and diphtheria vaccination are frequently insufficient in elderly persons.
A phase 1b randomized, controlled, double-blinded dosage-escalation trial to evaluate the safety, reactogenicity and immunogenicity of an adenovirus type 35 based circumsporozoite malaria vaccine in Burkinabe healthy adults 18 to 45 years of age.
Preserved antigen-specific immune response in patients with multiple sclerosis responding to IFNβ-therapy.
Biological, functional and genetic characterization of bone marrow-derived mesenchymal stromal cells from pediatric patients affected by acute lymphoblastic leukemia.
Lactobacilli regulate Staphylococcus aureus 161:2-induced pro-inflammatory T-cell responses in vitro.
Suppression of virus specific immune responses by IL-10 in acute dengue infection.
Expansion in CD39⁺ CD4⁺ immunoregulatory t cells and rarity of Th17 cells in HTLV-1 infected patients is associated with neurological complications.
An Influenza Virus M2 Protein Specific Chimeric Antigen Receptor Modulates Influenza A/WSN/33 H1N1 Infection In Vivo.
Protective CD8+ T-cell immunity to human malaria induced by chimpanzee adenovirus-MVA immunisation.
Brief Exercise Increases Peripheral Blood NK Cell Counts without Immediate Functional Changes, but Impairs their Responses to ex vivo Stimulation.
Placenta-derived gp96 as a multivalent prophylactic cancer vaccine.
T-Cell Response to Hepatitis B Core Antigen: Identification of Prior Exposure to and Confirmatory Testing for Screening for Anti-HBc.
Comparing effects of BK virus agnoprotein and herpes simplex-1 ICP47 on MHC-I and MHC-II expression.
Application of IgG-derived natural Treg epitopes (IgG Tregitopes) to antigen-specific tolerance induction in a murine model of type 1 diabetes.
Therapeutic DNA vaccination using in vivo electroporation followed by standard of care therapy in patients with genotype 1 chronic hepatitis C.
T-cell immunophenotyping distinguishes active from latent tuberculosis.
Enzyme-linked immunospot assay response to recombinant CFP-10/ESAT-6 fusion protein among patients with spinal tuberculosis: implications for diagnosis and monitoring of surgical therapy.
Autologous CLL cell vaccination early after transplant induces leukemia-specific T cells.
Lower CD28+ T cell proportions were associated with CMV-seropositivity in patients with Hashimoto's thyroiditis.
Lack of variant specific CD8+ T-cell response against mutant and pre-existing variants leads to outgrowth of particular clones in acute hepatitis C.
Generation of tumor antigen-specific T cell lines from pediatric patients with acute lymphoblastic leukemia--implications for immunotherapy.
Long-term CD4(+) and CD8(+) T-cell responses induced in HIV-uninfected volunteers following intradermal or intramuscular administration of an HIV-lipopeptide vaccine (ANRS VAC16).
The effect of rituximab on vaccine responses in patients with immune thrombocytopenia.
Characterization of the T-cell-mediated immune response against the Aspergillus fumigatus proteins Crf1 and catalase 1 in healthy individuals.
Temperature fluctuations during deep temperature cryopreservation reduce PBMC recovery, viability and T-cell function.
Evaluation of human cytomegalovirus-specific CD8+ T-cells in allogeneic haematopoietic stem cell transplant recipients using pentamer and interferon-γ-enzyme-linked immunospot assays.
Quantification of IFNγ- and IL17-producing cells after stimulation with citrullinated proteins in healthy subjects and RA patients.
Decreased functional T lymphocyte-mediated cytokine responses in patients with chemotherapy-induced neutropenia.
Modification of hematopoietic stem/progenitor cells with CD19-specific chimeric antigen receptors as a novel approach for cancer immunotherapy.
Response to HER-2 pulsed DC1 vaccines is predicted by both HER-2 and estrogen receptor expression in DCIS.
CMV-, EBV- and ADV-specific T cell immunity: screening and monitoring of potential third-party donors to improve post-transplantation outcome.
Cellular immune correlates of protection against symptomatic pandemic influenza.
Enhancement of tumor-reactive cytotoxic CD4+ T cell responses after ipilimumab treatment in four advanced melanoma patients.
Merkel polyomavirus-specific T cells fluctuate with merkel cell carcinoma burden and express therapeutically targetable PD-1 and Tim-3 exhaustion markers.
A case of sulfasalazine-induced hypersensitivity syndrome confirmed by enzyme-linked immunospot assay.
Maintenance of Th1 hepatitis C virus (HCV)-specific responses in individuals with acute HCV who achieve sustained virological clearance after treatment.
Identification of human leucocyte antigen (HLA)-A*0201-restricted cytotoxic T lymphocyte epitopes derived from HLA-DOβ as a novel target for multiple myeloma.
Structure-based design of altered MHC class II-restricted peptide ligands with heterogeneous immunogenicity.
High proportions of regulatory B and T cells are associated with decreased cellular responses to pH1N1 influenza vaccine in HIV-infected children and youth (IMPAACT P1088).
Immunological hallmarks of JC virus replication in multiple sclerosis patients on long-term natalizumab therapy.
A strategy to determine HLA class II restriction broadly covering the DR, DP, and DQ allelic variants most commonly expressed in the general population.
Effects of cyclophosphamide and IL-2 on regulatory CD4+ T cell frequency and function in melanoma patients vaccinated with HLA-class I peptides: impact on the antigen-specific T cell response.
Allelic exclusion and peripheral reconstitution by TCR transgenic T cells arising from transduced human hematopoietic stem/progenitor cells.
Discovering naturally processed antigenic determinants that confer protective T cell immunity.
Reduced varicella-zoster-virus (VZV)-specific lymphocytes and IgG antibody avidity in solid organ transplant recipients.
T cell memory to evolutionarily conserved and shared hemagglutinin epitopes of H1N1 viruses: a pilot scale study.
Comprehensive analysis of dengue virus-specific responses supports an HLA-linked protective role for CD8+ T cells.
Differential targeting of viral components by CD4+ versus CD8+ T lymphocytes in dengue virus infection.
Thalidomide maintenance therapy maturates the T cell compartment and compromises antigen-specific antitumor immunity in patients with multiple myeloma.
Human leucocyte antigen-Bw4 and Gag-specific T cell responses are associated with slow disease progression in HIV-1B-infected anti-retroviral therapy-naive Chinese.
In vitro diagnostic assays are effective during the acute phase of delayed-type drug hypersensitivity reactions.
Oral administration of an adenovirus vector encoding both an avian influenza A hemagglutinin and a TLR3 ligand induces antigen specific granzyme B and IFN-γ T cell responses in humans.
HLA-restricted CTL that are specific for the immune checkpoint ligand PD-L1 occur with high frequency in cancer patients.
Long-term survival after adoptive bone marrow T cell therapy of advanced metastasized breast cancer: follow-up analysis of a clinical pilot trial.
Rapid expansion of T cells: Effects of culture and cryopreservation and importance of short-term cell recovery.
Complement opsonization of HIV-1 results in a different intracellular processing pattern and enhanced MHC class I presentation by dendritic cells.
Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells.
Silencing of the glucocorticoid-induced leucine zipper improves the immunogenicity of clinical-grade dendritic cells.
CD141+ dendritic cells produce prominent amounts of IFN-α after dsRNA recognition and can be targeted via DEC-205 in humanized mice.
β-Lactam antibiotics form distinct haptenic structures on albumin and activate drug-specific T-lymphocyte responses in multiallergic patients with cystic fibrosis.
HLA Class II tetramers reveal tissue-specific regulatory T cells that suppress T-cell responses in breast carcinoma patients.
Hierarchy of CD4 T cell epitopes of the ANRS Lipo5 synthetic vaccine relies on the frequencies of pre-existing peptide-specific T cells in healthy donors.
HLA-B*44 is associated with a lower viral set point and slow CD4 decline in a cohort of Chinese homosexual men acutely infected with HIV-1.
A conserved human T cell population targets mycobacterial antigens presented by CD1b.
Therapeutic targeting of regulatory T cells enhances tumor-specific CD8+ T cell responses in Epstein-Barr virus associated nasopharyngeal carcinoma.
Serum IL-10 as a marker of severe dengue infection.
HLA peptide length preferences control CD8+ T cell responses.
Hepatitis B virus (HBV)-specific T-cell responses to recombinant HBV core protein in patients with normal liver function and co-infected with chronic HBV and human immunodeficiency virus 1 (HIV-1).
Melanoma-educated CD14+ cells acquire a myeloid-derived suppressor cell phenotype through COX-2-dependent mechanisms.
Interleukin-10 spot-forming cells as a novel biomarker of chronic graft-versus-host disease.
The potential of using enzyme-linked immunospot to diagnose cephalosporin-induced maculopapular exanthems.
Memory T cells in latent Mycobacterium tuberculosis infection are directed against three antigenic islands and largely contained in a CXCR3+CCR6+ Th1 subset.
A novel human autoantigen, endothelial cell growth factor, is a target of T and B cell responses in patients with Lyme disease.
Sipuleucel-T immune parameters correlate with survival: an analysis of the randomized phase 3 clinical trials in men with castration-resistant prostate cancer.
Short communication: broader T cell responses directed against human immunodeficiency virus type 1 in infected Chinese individuals through blood-borne transmission in comparison with mucosal transmission.
Enhanced function of redirected human T cells expressing linker for activation of T cells that is resistant to ubiquitylation.
Vertical T cell immunodominance and epitope entropy determine HIV-1 escape.
Functional single-cell analysis of T-cell activation by supported lipid bilayer-tethered ligands on arrays of nanowells.
CD8+ T Lymphocyte Epitopes From The Herpes Simplex Virus Type 2 ICP27, VP22 and VP13/14 Proteins To Facilitate Vaccine Design And Characterization.
Poor HIV control in HLA-B*27 and B*57/58 noncontrollers is associated with limited number of polyfunctional Gag p24-specific CD8+ T cells.
Lipoproteins are major targets of the polyclonal human T cell response to Mycobacterium tuberculosis.
Distinct HIV-1 escape patterns selected by cytotoxic T cells with identical epitope specificity.
Herpes simplex virus 2 (HSV-2) prevents dendritic cell maturation, induces apoptosis, and triggers release of proinflammatory cytokines: potential links to HSV-HIV synergy.
CD40L-Tri, a novel formulation of recombinant human CD40L that effectively activates B cells.
Human leukocyte antigen (HLA)-B*57:01-restricted activation of drug-specific T cells provides the immunological basis for flucloxacillin-induced liver injury.
A rationally engineered anti-HIV peptide fusion inhibitor with greatly reduced immunogenicity.
Relationship between chemokine receptor expression, chemokine levels and HIV-1 replication in the lungs of persons exposed to Mycobacterium tuberculosis.
Cancer regression and neurological toxicity following anti-MAGE-A3 TCR gene therapy.
Adults 65 years old and older have reduced numbers of functional memory T cells to respiratory syncytial virus fusion protein.
Comparing the safety and immunogenicity of a candidate TB vaccine MVA85A administered by intramuscular and intradermal delivery.
SHP2 is overexpressed and inhibits pSTAT1-mediated APM component expression, T-cell attracting chemokine secretion, and CTL recognition in head and neck cancer cells.
Epstein-Barr virus coinfection in children boosts cytomegalovirus-induced differentiation of natural killer cells.
Decreased HPV-specific T cell responses and accumulation of immunosuppressive influences in oropharyngeal cancer patients following radical therapy.
CD8(+) T-cell priming and boosting: more antigen-presenting DC, or more antigen per DC?
Functional characterization of Foxp3-specific spontaneous immune responses.
The MAPK pathway is a predominant regulator of HLA-A expression in esophageal and gastric cancer.
Cytomegalovirus-seropositive children show inhibition of in vitro EBV infection that is associated with CD8+CD57+ T cell enrichment and IFN-γ.
Quantitative and qualitative differences in the T cell response to HIV in uninfected Ugandans exposed or unexposed to HIV-infected partners.
Prenatal maternal anxiety predicts reduced adaptive immunity in infants.
Experimental respiratory Marburg virus haemorrhagic fever infection in the common marmoset (Callithrix jacchus).
Serum-free freezing media support high cell quality and excellent ELISPOT assay performance across a wide variety of different assay protocols.
CD1c tetramers detect ex vivo T cell responses to processed phosphomycoketide antigens.
Glycosylphosphatidylinositol-specific, CD1d-restricted T cells in paroxysmal nocturnal hemoglobinuria.
Phase I clinical trial of human vascular endothelial growth factor receptor 1 peptide vaccines for patients with metastatic renal cell carcinoma.
Long-term Vaccination with Multiple Peptides Derived from Cancer-Testis Antigens Can Maintain a Specific T-cell Response and Achieve Disease Stability in Advanced Biliary Tract Cancer.
Multiple therapeutic peptide vaccines consisting of combined novel cancer testis antigens and anti-angiogenic peptides for patients with non-small cell lung cancer.
The immune checkpoint regulator PD-L1 is a specific target for naturally occurring CD4(+) T cells.
The EBV immunoevasins vIL-10 and BNLF2a protect newly infected B cells from immune recognition and elimination.
Recovered patients with Stevens-Johson syndrome and toxic epidermal necrolysis maintain long-lived IFN-γ and sFasL memory response.
MRKAd5 HIV-1 Gag/Pol/Nef vaccine-induced T-cell responses inadequately predict distance of breakthrough HIV-1 sequences to the vaccine or viral load.
HIV-1 envelope resistance to proteasomal cleavage: implications for vaccine induced immune responses.
Estimating point and interval frequency of antigen-specific CD4+ T cells based on short in vitro expansion and improved poisson distribution analysis.
Pertussis circulation has increased T-cell immunity during childhood more than a second acellular booster vaccination in Dutch children 9 years of age.
The effect of HLA polymorphisms on the recognition of Gag epitopes in HIV-1 CRF01_AE infection.
Distinct effector memory CD4+ T cell signatures in latent Mycobacterium tuberculosis infection, BCG vaccination and clinically resolved tuberculosis.
Natural CD4+ T-cell responses against indoleamine 2,3-dioxygenase.
Low-replicating viruses and strong anti-viral immune response associated with prolonged disease control in a superinfected HIV-1 LTNP elite controller.
Revisiting the effect of acute P. falciparum malaria on Epstein-Barr virus: host balance in the setting of reduced malaria endemicity.
Differential expression of CD96 surface molecule represents CD8⁺ T cells with dissimilar effector function during HIV-1 infection.
Early-life gut bacteria associate with IL-4-, IL-10- and IFN-γ production at two years of age.
Generation and characterization of a defective HIV-1 Virus as an immunogen for a therapeutic vaccine.
Biomarkers of Plasmodium falciparum infection during pregnancy in women living in northeastern Tanzania.
Fragmentation of SIV-gag vaccine induces broader T cell responses.
CTL responses of high functional avidity and broad variant cross-reactivity are associated with HIV control.
PLGA nanoparticle-mediated delivery of tumor antigenic peptides elicits effective immune responses.
Tumor associated antigen specific T-cell populations identified in ex vivo expanded TIL cultures.
Human microRNA-1245 down-regulates the NKG2D receptor in natural killer cells and impairs NKG2D-mediated functions.
A human CD4+ T cell epitope in the influenza hemagglutinin is cross-reactive to influenza A virus subtypes and to influenza B virus.
The effect of chronological age on the inflammatory response of human fibroblasts.
HCV coinfection does not alter the frequency of regulatory T cells or CD8+ T cell immune activation in chronically infected HIV+ Chinese subjects.
Ad3-hTERT-E1A, a fully serotype 3 oncolytic adenovirus, in patients with chemotherapy refractory cancer.
Comparison of in vivo Adjuvanticity of Liposomal PO CpG ODN with Liposomal PS CpG ODN: Soluble Leishmania Antigens as a Model.
T cells engineered with a T cell receptor against the prostate antigen TARP specifically kill HLA-A2+ prostate and breast cancer cells.
Prolonged persistence of measles virus RNA is characteristic of primary infection dynamics.
Metastatic melanoma patients treated with dendritic cell vaccination, Interleukin-2 and metronomic cyclophosphamide: results from a phase II trial.
Mutated BCR-ABL generates immunogenic T-cell epitopes in CML patients.
Detecting T-cell reactivity to whole cell vaccines: Proof of concept analysis of T-cell response to K562 cell antigens in CML patients.
Survivin-specific T-cell reactivity correlates with tumor response and patient survival: a phase-II peptide vaccination trial in metastatic melanoma.
Controlled-rate freezer cryopreservation of highly concentrated peripheral blood mononuclear cells results in higher cell yields and superior autologous T-cell stimulation for dendritic cell-based immunotherapy.
The simultaneous ex vivo detection of low-frequency antigen-specific CD4+ and CD8+ T-cell responses using overlapping peptide pools.
HCV genotype-3a T cell immunity: specificity, function and impact of therapy.
Predominance of heterosubtypic IFN-γ-only-secreting effector memory T cells in pandemic H1N1 naive adults.
T-cell responses before and after the fifth consecutive acellular pertussis vaccination in 4-year-old Dutch children.
HIV-1-specific enzyme-linked immunosorbent spot assay responses in HIV-1-exposed uninfected partners in discordant relationships compared to those in low-risk controls.
Heteroclitic peptides enhance human immunodeficiency virus-specific CD8(+) T cell responses.
Dendritic cell vaccination in glioblastoma after fluorescence-guided resection.
Characterization of T-cell responses against IκBα in cancer patients.
Immunity to the melanoma inhibitor of apoptosis protein (ML-IAP; livin) in patients with malignant melanoma.
Safety and immunogenicity of vaccination with MART-1 (26-35, 27L), gp100 (209-217, 210M), and tyrosinase (368-376, 370D) in adjuvant with PF-3512676 and GM-CSF in metastatic melanoma.
Preferential CTL targeting of Gag is associated with relative viral control in long-term surviving HIV-1 infected former plasma donors from China.
Lower numbers of natural killer T cells in HIV-1 and Mycobacterium leprae co-infected patients.
RNAs in Epstein-Barr virions control early steps of infection.
Age of recipient and number of doses differentially impact human B and T cell immune memory responses to HPV vaccination.
The Thai phase III trial (RV144) vaccine regimen induces T cell responses that preferentially target epitopes within the V2 region of HIV-1 envelope.
Dissecting mechanisms of immunodominance to the common tuberculosis antigens ESAT-6, CFP10, Rv2031c (hspX), Rv2654c (TB7.7), and Rv1038c (EsxJ).
Human dendritic cells adenovirally-engineered to express three defined tumor antigens promote broad adaptive and innate immunity.
A gynecologic oncology group phase II trial of two p53 peptide vaccine approaches: subcutaneous injection and intravenous pulsed dendritic cells in high recurrence risk ovarian cancer patients.
Novel myeloma-associated antigens revealed in the context of syngeneic hematopoietic stem cell transplantation.
The ganglioside antigen G(D2) is surface-expressed in Ewing sarcoma and allows for MHC-independent immune targeting.
Effective treatment of metastatic forms of Epstein-Barr virus-associated nasopharyngeal carcinoma with a novel adenovirus-based adoptive immunotherapy.
Exploiting the mutanome for tumor vaccination.
Vaccination with dendritic cells loaded with tumor apoptotic bodies (Apo-DC) in patients with chronic lymphocytic leukemia: effects of various adjuvants and definition of immune response criteria.
Altered serum pro-inflammatory cytokines in children with Down's syndrome.
Therapeutic potential of transplanted placental mesenchymal stem cells in treating Chinese miniature pigs with acute liver failure.
Drug hypersensitivity caused by alteration of the MHC-presented self-peptide repertoire.
Humoral and cellular capsid-specific immune responses to adeno-associated virus type 1 in randomized healthy donors.
Invariant natural killer T cells are not affected by lysosomal storage in patients with Niemann-Pick disease type C.
Human papillomavirus immunization is associated with increased expression of different innate immune regulatory receptors.
Peptide-pulsed dendritic cell vaccination targeting interleukin-13 receptor α2 chain in recurrent malignant glioma patients with HLA-A*24/A*02 allele.
Protective effect of human endogenous retrovirus K dUTPase variants on psoriasis susceptibility.
Multicenter, phase II clinical trial of cancer vaccination for advanced esophageal cancer with three peptides derived from novel cancer-testis antigens.
Human tissues contain CD141hi cross-presenting dendritic cells with functional homology to mouse CD103+ nonlymphoid dendritic cells.
Analysis of T cell responses to the major allergens from German cockroach: epitope specificity and relationship to IgE production.
Association of a functional Indoleamine 2,3-dioxygenase 2 genotype with specific immune responses.
HIV-specific CD4 T cell responses to different viral proteins have discordant associations with viral load and clinical outcome.
HIV-1 infection alters CD4+ memory T-cell phenotype at the site of disease in extrapulmonary tuberculosis.
Humoral and cell-mediated immune responses to monovalent 2009 influenza A/H1N1 and seasonal trivalent influenza vaccines in high-risk children.
Human adenovirus-specific T cells modulate HIV-specific T cell responses to an Ad5-vectored HIV-1 vaccine.
Vaccine vectors derived from a large collection of simian adenoviruses induce potent cellular immunity across multiple species.
Novel adenovirus-based vaccines induce broad and sustained T cell responses to HCV in man.
A new antigen scanning strategy for monitoring HIV-1 specific T-cell immune responses.
High-avidity, high-IFNγ-producing CD8 T-cell responses following immune selection during HIV-1 infection.
Characterization and comparison of 'standard' and 'young' tumour-infiltrating lymphocytes for adoptive cell therapy at a Danish translational research institution.
Developing a new clinical tool for diagnosing chronic Q fever: the Coxiella ELISPOT.
T-cell therapy for EBV-associated nasopharyngeal carcinoma: preparative lymphodepleting chemotherapy does not improve clinical results.
Human endogenous retrovirus K(HML-2) Gag- and Env-specific T-cell responses are infrequently detected in HIV-1-infected subjects using standard peptide matrix-based screening.
Dynamics of cell-mediated immune responses to cytomegalovirus in pediatric transplantation recipients.
Modification of the carboxy-terminal flanking region of a universal influenza epitope alters CD4⁺ T-cell repertoire selection.
Inclusion of a CRF01_AE HIV envelope protein boost with a DNA/MVA prime-boost vaccine: Impact on humoral and cellular immunogenicity and viral load reduction after SHIV-E challenge.
IL-21 can supplement suboptimal Lck-independent MAPK activation in a STAT-3-dependent manner in human CD8(+) T cells.
Phase 1 clinical trial of HER2-specific immunotherapy with concomitant HER2 kinase inhibition [corrected].
Immunological status in patients undergoing in vitro fertilisation: responses to hormone treatment and relationship to outcome.
Induction of MAGE-A3 and HPV-16 immunity by Trojan vaccines in patients with head and neck carcinoma.
The high frequency of HIV type 1-specific cellular immune responses in seronegative individuals with parenteral and/or heterosexual HIV type 1 exposure.
α-type-1 polarized dendritic cell-based vaccination in recurrent high-grade glioma: a phase I clinical trial.
Conservation of HIV-1 T cell epitopes across time and clades: validation of immunogenic HLA-A2 epitopes selected for the GAIA HIV vaccine.
Limited induction of tumor cross-reactive T cells without a measurable clinical benefit in early melanoma patients vaccinated with human leukocyte antigen class I-modified peptides.
Endometrial receptivity defects and impaired implantation in diabetic NOD mice.
Ex vivo enrichment of circulating anti-tumor T cells from both cutaneous and ocular melanoma patients: clinical implications for adoptive cell transfer therapy.
Suppression of tumour-specific CD4⁺ T cells by regulatory T cells is associated with progression of human colorectal cancer.
Generating CTLs against the subdominant EBV LMP antigens by transient expression of an A20 inhibitor with EBV LMP proteins in human DCs.
Short wheat challenge is a reproducible in-vivo assay to detect immune response to gluten.
Adoptive cell therapy with autologous tumor infiltrating lymphocytes and low-dose Interleukin-2 in metastatic melanoma patients.
T cell responses to known allergen proteins are differently polarized and account for a variable fraction of total response to allergen extracts.
Doxycycline-mediated effects on persistent symptoms and systemic cytokine responses post-neuroborreliosis: a randomized, prospective, cross-over study.
Widespread CD4+ T-cell reactivity to novel hTERT epitopes following vaccination of cancer patients with a single hTERT peptide GV1001.
Identification of an immunodominant region of the major house dust mite allergen Der p 2 presented by common human leucocyte antigen alleles.
Changes in the levels of cytokines, chemokines and malaria-specific antibodies in response to Plasmodium falciparum infection in children living in sympatry in Mali.
Phase I randomised clinical trial of an HIV-1(CN54), clade C, trimeric envelope vaccine candidate delivered vaginally.
A novel immunodominant CD8+ T cell response restricted by a common HLA-C allele targets a conserved region of Gag HIV-1 clade CRF01_AE infected Thais.
Unique CRF01_AE Gag CTL epitopes associated with lower HIV-viral load and delayed disease progression in a cohort of HIV-infected Thais.
A molecular assay for sensitive detection of pathogen-specific T-cells.
Vaccination against heterologous R5 clade C SHIV: prevention of infection and correlates of protection.
Immunodominance of HIV-1 specific CD8+ T-cell responses is related to disease progression rate in vertically infected adolescents.
Day-4 myeloid dendritic cells pulsed with whole tumor lysate are highly immunogenic and elicit potent anti-tumor responses.
Evaluation of approaches to identify the targets of cellular immunity on a proteome-wide scale.
An MSI tumor specific frameshift mutation in a coding microsatellite of MSH3 encodes for HLA-A0201-restricted CD8+ cytotoxic T cell epitopes.
Identification of antigens specific to non-tuberculous mycobacteria: the Mce family of proteins as a target of T cell immune responses.
Intra- and inter-clade cross-reactivity by HIV-1 Gag specific T-cells reveals exclusive and commonly targeted regions: implications for current vaccine trials.
Circumsporozoite-specific T cell responses in children vaccinated with RTS,S/AS01E and protection against P falciparum clinical malaria.
Direct ex-vivo evaluation of pneumococcal specific T-cells in healthy adults.
EBV-gp350 confers B-cell tropism to tailored exosomes and is a neo-antigen in normal and malignant B cells--a new option for the treatment of B-CLL.
Evidence of hepatitis E virus exposure among seronegative healthy residents of an endemic area.
Immunosenescent CD57+CD4+ T-cells accumulate and contribute to interferon-γ responses in HIV patients responding stably to ART.
Characterization of ex vivo expanded tumor infiltrating lymphocytes from patients with malignant melanoma for clinical application.
Safety and Immunogenicity of a Human Papillomavirus Peptide Vaccine (CIGB-228) in Women with High-Grade Cervical Intraepithelial Neoplasia: First-in-Human, Proof-of-Concept Trial.
Standardized Serum-Free Cryomedia Maintain Peripheral Blood Mononuclear Cell Viability, Recovery, and Antigen-Specific T-Cell Response Compared to Fetal Calf Serum-Based Medium.
Phase I (safety) study of autologous tolerogenic dendritic cells in type 1 diabetic patients.
Immunological effects of low-dose cyclophosphamide in cancer patients treated with oncolytic adenovirus.
Antigen-specific T cell responses to BK polyomavirus antigens identify functional anti-viral immunity and may help to guide immunosuppression following renal transplantation.
A poxvirus vaccine is safe, induces T-cell responses, and decreases viral load in patients with chronic hepatitis C.
Effect of oxygen levels on the physiology of dendritic cells: implications for adoptive cell therapy.
Semiallogenic fusions of MSI(+) tumor cells and activated B cells induce MSI-specific T cell responses.
Development of an interferon-gamma ELISPOT assay to detect human T cell responses to HSV-2.
Functional gap junctions accumulate at the immunological synapse and contribute to T cell activation.
Augmented HIV-specific interferon-gamma responses, but impaired lymphoproliferation during interruption of antiretroviral treatment initiated in primary HIV infection.
Limited immunogenicity of HIV CD8+ T-cell epitopes in acute Clade C virus infection.
Translation of HLA-HIV associations to the cellular level: HIV adapts to inflate CD8 T cell responses against Nef and HLA-adapted variant epitopes.
Differences in Kaposi sarcoma-associated herpesvirus-specific and herpesvirus-non-specific immune responses in classic Kaposi sarcoma cases and matched controls in Sicily.
A human Phase I/IIa malaria challenge trial of a polyprotein malaria vaccine.
Broad and potent immune responses to a low dose intradermal HIV-1 DNA boosted with HIV-1 recombinant MVA among healthy adults in Tanzania.
Virus aggregating peptide enhances the cell-mediated response to influenza virus vaccine.
Cell-mediated immune responses to inactivated trivalent influenza-vaccination are decreased in patients with common variable immunodeficiency.
Immunization with the RTS,S/AS malaria vaccine induces IFN-γ(+)CD4 T cells that recognize only discrete regions of the circumsporozoite protein and these specificities are maintained following booster immunizations and challenge.
Age-related changes in durability and function of vaccine-elicited influenza-specific CD4(+) T-cell responses.
Merkel cell polyomavirus-specific CD8⁺ and CD4⁺ T-cell responses identified in Merkel cell carcinomas and blood.
Distinguishing between the innate immune response due to ocular inflammation and infection in a child with juvenile systemic granulomatous disease treated with anti-TNFα monoclonal antibodies.
Hypercytokinaemia accompanies HIV-tuberculosis immune reconstitution inflammatory syndrome.
Identification of T cell epitopes on soluble liver antigen in Chinese patients with auto-immune hepatitis.
CD200 expression suppresses natural killer cell function and directly inhibits patient anti-tumor response in acute myeloid leukemia.
The clinical value of concomitant Epstein Barr virus (EBV)-DNA load and specific immune reconstitution monitoring after allogeneic hematopoietic stem cell transplantation.
IFN-α boosts epitope cross-presentation by dendritic cells via modulation of proteasome activity.
The polyomavirus BK large T-antigen-derived peptide elicits an HLA-DR promiscuous and polyfunctional CD4+ T-cell response.
Systematic identification of immunodominant CD8+ T-cell responses to influenza A virus in HLA-A2 individuals.
Th17/Th1 biased immunity to the pneumococcal proteins PcsB, StkP and PsaA in adults of different age.
EBV-specific CD8+ T cells from asymptomatic pediatric thoracic transplant patients carrying chronic high EBV loads display contrasting features: activated phenotype and exhausted function.
Natural killer cells from children with type 1 diabetes have defects in NKG2D-dependent function and signaling.
Cotransfection of Poly(I: C) and siRNA of IL-10 into fusions of dendritic and glioma cells enhances antitumor T helper type 1 induction in patients with glioma.
Cytokine expression in tumors treated with donor lymphocyte infusions after allogeneic hematopoietic stem cell transplantation.
FLT3-regulated antigens as targets for leukemia-reactive cytotoxic T lymphocytes.
Effect of hookworm infection on wheat challenge in celiac disease--a randomised double-blinded placebo controlled trial.
Interethnic differences in antigen-presenting cell activation and TLR responses in Malian children during Plasmodium falciparum malaria.
Decreased Th1-type inflammatory cytokine expression in the skin is associated with persisting symptoms after treatment of erythema migrans.
CD8+ T cell immunity to 2009 pandemic and seasonal H1N1 influenza viruses.
Ag85B-ESAT-6 adjuvanted with IC31® promotes strong and long-lived Mycobacterium tuberculosis specific T cell responses in volunteers with previous BCG vaccination or tuberculosis infection.
Specific recognition and inhibition of Ewing tumour growth by antigen-specific allo-restricted cytotoxic T cells.
Intratumor T helper type 2 cell infiltrate correlates with cancer-associated fibroblast thymic stromal lymphopoietin production and reduced survival in pancreatic cancer.
Comparison of antibody and T-cell responses elicited by licensed inactivated- and live-attenuated influenza vaccines against H3N2 hemagglutinin.
Impaired tumor antigen processing by immunoproteasome-expressing CD40-activated B cells and dendritic cells.
Interferon-γ and proliferation responses to Salmonella enterica Serotype Typhi proteins in patients with S. Typhi Bacteremia in Dhaka, Bangladesh.
Quantitative analysis of the CD4 T-cell repertoire specific to therapeutic antibodies in healthy donors.
A mycolic acid-specific CD1-restricted T cell population contributes to acute and memory immune responses in human tuberculosis infection.
Characterization of a branched lipopeptide candidate vaccine against influenza A/Puerto Rico 8/34 which is recognized by human B and T-cell immune responses.
Human dendritic cell subsets from spleen and blood are similar in phenotype and function but modified by donor health status.
Strong human endogenous retrovirus-specific T cell responses are associated with control of HIV-1 in chronic infection.
Identification of Hydroxysteroid (17β) dehydrogenase type 12 (HSD17B12) as a CD8+ T-cell-defined human tumor antigen of human carcinomas.
Decreased IFNγ production correlates with diminished production of cytokines by dendritic cells in patients infected with hepatitis C virus and receiving therapy.
The reconstitution of the thymus in immunosuppressed individuals restores CD4-specific cellular and humoral immune responses.
Preparation, characterisation and entrapment of a non-glycosidic threitol ceramide into liposomes for presentation to invariant natural killer T cells.
Phylogenetic analysis consistent with a clinical history of sexual transmission of HIV-1 from a single donor reveals transmission of highly distinct variants.
Single-walled carbon nanotubes deliver peptide antigen into dendritic cells and enhance IgG responses to tumor-associated antigens.
Amplified antigen-specific immune responses in HIV-1 infected individuals in a double blind DNA immunization and therapy interruption trial.
Multilayered defense in HLA-B51-associated HIV viral control.
Lenalidomide enhances antigen-specific activity and decreases CD45RA expression of T cells from patients with multiple myeloma.
Phase I study utilizing a novel antigen-presenting cell-targeted vaccine with Toll-like receptor stimulation to induce immunity to self-antigens in cancer patients.
Multidrug-resistance proteins are weak tumor associated antigens for colorectal carcinoma.
CD4-positive T-helper cell responses to the PASD1 protein in patients with diffuse large B-cell lymphoma.
Synbiotics reduce allergen-induced T-helper 2 response and improve peak expiratory flow in allergic asthmatics.
Hepatitis C virus-specific CD8+ T cell frequencies are associated with the responses of pegylated interferon-α and ribavirin combination therapy in patients with chronic hepatitis C virus infection.
Phase I clinical trial of a novel peptide vaccine in combination with UFT/LV for metastatic colorectal cancer.
High immunogenic potential of p53 mRNA-transfected dendritic cells in patients with primary breast cancer.
Antibody-targeted NY-ESO-1 to mannose receptor or DEC-205 in vitro elicits dual human CD8+ and CD4+ T cell responses with broad antigen specificity.
A live attenuated Listeria monocytogenes vaccine vector expressing SIV Gag is safe and immunogenic in macaques and can be administered repeatedly.
Biologic and immunologic effects of preoperative trastuzumab for ductal carcinoma in situ of the breast.
Immune responses and protection of Aotus monkeys immunized with irradiated Plasmodium vivax sporozoites.
Antibody-mediated and cellular immune responses induced in naive volunteers by vaccination with long synthetic peptides derived from the Plasmodium vivax circumsporozoite protein.
Phase I safety and immunogenicity trial of Plasmodium vivax CS derived long synthetic peptides adjuvanted with montanide ISA 720 or montanide ISA 51.
Identification of a cyclin B1-derived CTL epitope eliciting spontaneous responses in both cancer patients and healthy donors.
Partially randomized, non-blinded trial of DNA and MVA therapeutic vaccines based on hepatitis B virus surface protein for chronic HBV infection.
In vivo expression of human T-lymphotropic virus type 1 basic leucine-zipper protein generates specific CD8+ and CD4+ T-lymphocyte responses that correlate with clinical outcome.
Cellular immune responses in patients with hepatitis B surface antigen seroclearance induced by antiviral therapy.
Cytolytic T lymphocytes from HLA-B8+ donors frequently recognize the Hodgkin's lymphoma associated latent membrane protein 2 of Epstein Barr virus.
Alterations in immune function are associated with liver enzyme elevation in HIV and HCV co-infection after commencement of combination antiretroviral therapy.
Identification of three novel CTL epitopes within nucleocapsid protein of Hantaan virus.
An engineered Plasmodium falciparum C-terminal 19-kilodalton merozoite surface protein 1 vaccine candidate induces high levels of interferon-gamma production associated with cellular immune responses to specific peptide sequences in Gambian adults naturally exposed to malaria.
Definition of the viral targets of protective HIV-1-specific T cell responses.
Pilot clinical trial of type 1 dendritic cells loaded with autologous tumor lysates combined with GM-CSF, pegylated IFN, and cyclophosphamide for metastatic cancer patients.
The immune response to the RT181-189 epitope in HIV-1-infected patients is associated with viral sequence polymorphism flanking the epitope.
Clinical significance of interleukin-2/gamma interferon ratios in Mycobacterium tuberculosis-specific T-cell signatures.
Bimodal ex vivo expansion of T cells from patients with head and neck squamous cell carcinoma: a prerequisite for adoptive cell transfer.
A whole blood monokine-based reporter assay provides a sensitive and robust measurement of the antigen-specific T cell response.
Precursor frequency and competition dictate the HLA-A2-restricted CD8+ T cell responses to influenza A infection and vaccination in HLA-A2.1 transgenic mice.
Human epidermal Langerhans cells replenish skin xenografts and are depleted by alloreactive T cells in vivo.
Differences in HIV-specific T cell responses between HIV-exposed and -unexposed HIV-seronegative individuals.
Deficiency of activated STAT1 in head and neck cancer cells mediates TAP1-dependent escape from cytotoxic T lymphocytes.
Altered decamer and nonamer from an HLA-A0201-restricted epitope of Survivin differentially stimulate T-cell responses in different individuals.
Rv3615c is a highly immunodominant RD1 (Region of Difference 1)-dependent secreted antigen specific for Mycobacterium tuberculosis infection.
HTLV-1 tax specific CD8+ T cells express low levels of Tim-3 in HTLV-1 infection: implications for progression to neurological complications.
Differential cellular recognition of antigens during acute Plasmodium falciparum and Plasmodium vivax malaria.
Peptide-loaded Langerhans cells, despite increased IL15 secretion and T-cell activation in vitro, elicit antitumor T-cell responses comparable to peptide-loaded monocyte-derived dendritic cells in vivo.
JAK3/STAT5/6 pathway alterations are associated with immune deviation in CD8 T cells in renal cell carcinoma patients.
Identification of an MSI-H tumor-specific cytotoxic T cell epitope generated by the (-1) frame of U79260(FTO).
Risk factors and immune response to hepatitis E viral infection among acute hepatitis patients in Assiut, Egypt.
Diversity in CD8(+) T cell function and epitope breadth among persons with genital herpes.
IL-2 immunotherapy to recently HIV-1 infected adults maintains the numbers of IL-17 expressing CD4+ T (T(H)17) cells in the periphery.
Efficacy of dendritic cells matured early with OK-432 (Picibanil), prostaglandin E2, and interferon-alpha as a vaccine for a hormone refractory prostate cancer cell line.
Comparison of immunologic assays for detecting immune responses in HIV immunotherapeutic studies: AIDS Clinical Trials Group Trial A5181.
HLA class I binding of HBZ determines outcome in HTLV-1 infection.
Dendritic cells reveal a broad range of MHC class I epitopes for HIV-1 in persons with suppressed viral load on antiretroviral therapy.
A conserved E7-derived cytotoxic T lymphocyte epitope expressed on human papillomavirus 16-transformed HLA-A2+ epithelial cancers.
Dynamic correlation between CTL response and viral load in primary human immunodeficiency virus-1 infected Koreans.
Immunodominant HIV-specific CD8+ T-cell responses are common to blood and gastrointestinal mucosa, and Gag-specific responses dominate in rectal mucosa of HIV controllers.
CD8+ T cell recognition of polymorphic wild-type sequence p53(65-73) peptides in squamous cell carcinoma of the head and neck.
Treatment of cancer patients with a serotype 5/3 chimeric oncolytic adenovirus expressing GMCSF.
Monofunctional and polyfunctional CD8+ T cell responses to human herpesvirus 8 lytic and latency proteins.
Methanol induces a discrete transcriptional dysregulation that leads to cytokine overproduction in activated lymphocytes.
Safety and immunogenicity of a replication-defective adenovirus type 5 HIV vaccine in Ad5-seronegative persons: a randomized clinical trial (HVTN 054).
CD8 controls T cell cross-reactivity.
CD8+ T cells as a source of IFN-γ production in human cutaneous leishmaniasis.
Screening of human tumor antigens for CD4 T cell epitopes by combination of HLA-transgenic mice, recombinant adenovirus and antigen peptide libraries.
A comprehensive ex vivo functional analysis of human NKT cells reveals production of MIP1-α and MIP1-β, a lack of IL-17, and a Th1-bias in males.
Phase I safety and immunogenicity evaluation of MVA-CMDR, a multigenic, recombinant modified vaccinia Ankara-HIV-1 vaccine candidate.
A randomized trial of ex vivo CD40L activation of a dendritic cell vaccine in colorectal cancer patients: tumor-specific immune responses are associated with improved survival.
Virus-specific CD8+ T-cell responses better define HIV disease progression than HLA genotype.
Identification of broad binding class I HLA supertype epitopes to provide universal coverage of influenza A virus.
Naturally occurring systemic immune responses to HPV antigens do not predict regression of CIN2/3.
3-hydroxyphthalic anhydride-modified chicken ovalbumin exhibits potent and broad anti-HIV-1 activity: a potential microbicide for preventing sexual transmission of HIV-1.
Polyclonal expansion of cervical cytobrush-derived T cells to investigate HIV-specific responses in the female genital tract.
Human immunodeficiency virus-1 inhibition of immunoamphisomes in dendritic cells impairs early innate and adaptive immune responses.
Reversion and conversion of Mycobacterium tuberculosis IFN-gamma ELISpot results during anti-tuberculous treatment in HIV-infected children.
Human immunodeficiency virus type I-specific CD8+ T cell subset abnormalities in chronic infection persist through effective antiretroviral therapy.
Identification of T. gondii epitopes, adjuvants, and host genetic factors that influence protection of mice and humans.
Construction and immunogenicity of replication-competent adenovirus 5 host range mutant recombinants expressing HIV-1 gp160 of SF162 and TV1 strains.
Graft-versus-leukemia antigen CML66 elicits coordinated B-cell and T-cell immunity after donor lymphocyte infusion.
Human immunodeficiency virus (HIV) infection during pregnancy induces CD4 T-cell differentiation and modulates responses to Bacille Calmette-Guérin (BCG) vaccine in HIV-uninfected infants.
Detailed characterization of T cell responses to herpes simplex virus-2 in immune seronegative persons.
Anti-inflammatory triterpenoid blocks immune suppressive function of MDSCs and improves immune response in cancer.
Virological footprint of CD4+ T-cell responses during chronic hepatitis C virus infection.
Enhanced anti-HIV functional activity associated with Gag-specific CD8 T-cell responses.
Different in vivo effects of HIV-1 immunodominant epitope-specific cytotoxic T lymphocytes on selection of escape mutant viruses.
HLA-A2-restricted T-cell epitopes specific for prostatic acid phosphatase.
Development of a cross-platform biomarker signature to detect renal transplant tolerance in humans.
Vaccination with a plasmid DNA encoding HER-2/neu together with low doses of GM-CSF and IL-2 in patients with metastatic breast carcinoma: a pilot clinical trial.
The small molecule curcumin analog FLLL32 induces apoptosis in melanoma cells via STAT3 inhibition and retains the cellular response to cytokines with anti-tumor activity.
Correlates of spontaneous viral control among long-term survivors of perinatal HIV-1 infection expressing human leukocyte antigen-B57.
Synergism from combined immunologic and pharmacologic inhibition of HER2 in vivo.
Control of HIV-1 in elite suppressors despite ongoing replication and evolution in plasma virus.
Variation in gamma interferon responses to different infecting strains of Mycobacterium tuberculosis in acid-fast bacillus smear-positive patients and household contacts in Antananarivo, Madagascar.
Virally infected and matured human dendritic cells activate natural killer cells via cooperative activity of plasma membrane-bound TNF and IL-15.
An investigation of clinical and immunological events following repeated aerodigestive tract challenge infections with live Mycobacterium bovis Bacille Calmette Guérin.
Unexpected diversity of cellular immune responses against Nef and Vif in HIV-1-infected patients who spontaneously control viral replication.
Molecular determinants of T cell epitope recognition to the common Timothy grass allergen.
Vaccination with synthetic analog peptides derived from WT1 oncoprotein induces T-cell responses in patients with complete remission from acute myeloid leukemia.
Could a loss of memory T cells limit responses to hepatitis C virus (HCV) antigens in blood leucocytes from patients chronically infected with HCV before and during pegylated interferon-alpha and ribavirin therapy?
Novel approach to the formulation of an Epstein-Barr virus antigen-based nasopharyngeal carcinoma vaccine.
Modified vaccinia Ankara-expressing Ag85A, a novel tuberculosis vaccine, is safe in adolescents and children, and induces polyfunctional CD4+ T cells.
Novel immunogenic HLA-A*0201-restricted epidermal growth factor receptor-specific T-cell epitope in head and neck cancer patients.
Cellular immune responses against CT7 (MAGE-C1) and humoral responses against other cancer-testis antigens in multiple myeloma patients.
A pilot clinical trial testing mutant von Hippel-Lindau peptide as a novel immune therapy in metastatic renal cell carcinoma.
Viral adaptation to immune selection pressure by HLA class I-restricted CTL responses targeting epitopes in HIV frameshift sequences.
Elevated Epstein-Barr virus-encoded nuclear antigen-1 immune responses predict conversion to multiple sclerosis.
Hepatocellular carcinoma immunopathogenesis: clinical evidence for global T cell defects and an immunomodulatory role for soluble CD25 (sCD25).
The establishment of dendritic cell-tumor fusion vaccines for hormone refractory prostate cancer cell.
DC expressing transgene Foxp3 are regulatory APC.
HIV controller CD4+ T cells respond to minimal amounts of Gag antigen due to high TCR avidity.
Healthy human T-Cell Responses to Aspergillus fumigatus antigens.
A case of seronegative HIV-1 infection.
Peripheral blood invariant natural killer T cells throughout pregnancy and in preeclamptic women.
Sequence evolution of HIV-1 following mother-to-child transmission.
CD1a-autoreactive T cells are a normal component of the human αβ T cell repertoire.
Human immunome, bioinformatic analyses using HLA supermotifs and the parasite genome, binding assays, studies of human T cell responses, and immunization of HLA-A*1101 transgenic mice including novel adjuvants provide a foundation for HLA-A03 restricted CD8+T cell epitope based, adjuvanted vaccine protective against Toxoplasma gondii.
Hypoxia induces an immunodominant target of tuberculosis specific T cells absent from common BCG vaccines.
Optimization of storage and shipment of cryopreserved peripheral blood mononuclear cells from HIV-infected and uninfected individuals for ELISPOT assays.
Enumeration of functional T-cell subsets by fluorescence-immunospot defines signatures of pathogen burden in tuberculosis.
Equivalence of ELISpot assays demonstrated between major HIV network laboratories.
Fine analysis of spontaneous MAGE-C1/CT7-specific immunity in melanoma patients.
Cerebrospinal T-cell responses aid in the diagnosis of tuberculous meningitis in a human immunodeficiency virus- and tuberculosis-endemic population.
Inverse correlation of HER2 with MHC class I expression on oesophageal squamous cell carcinoma.
Serum is not required for ex vivo IFN-gamma ELISPOT: a collaborative study of different protocols from the European CIMT Immunoguiding Program.
Performance of serum-supplemented and serum-free media in IFNgamma Elispot Assays for human T cells.
Accelerated production of antigen-specific T cells for preclinical and clinical applications using gas-permeable rapid expansion cultureware (G-Rex).
Changes in function of HIV-specific T-cell responses with increasing time from infection.
Cellular immunity in children with successful immunoprophylactic treatment for mother-to-child transmission of hepatitis B virus.
Rapid progressing allele HLA-B35 Px restricted anti-HIV-1 CD8+ T cells recognize vestigial CTL epitopes.
MHC class I molecules with Superenhanced CD8 binding properties bypass the requirement for cognate TCR recognition and nonspecifically activate CTLs.
Phase 1/2a study of the malaria vaccine candidate apical membrane antigen-1 (AMA-1) administered in adjuvant system AS01B or AS02A.
Immunodominant HIV-1 Cd4+ T cell epitopes in chronic untreated clade C HIV-1 infection.
A-kinase anchoring in dendritic cells is required for antigen presentation.
Fludarabine modulates immune response and extends in vivo survival of adoptively transferred CD8 T cells in patients with metastatic melanoma.
Effect of methotrexate and anti-TNF on Epstein-Barr virus T-cell response and viral load in patients with rheumatoid arthritis or spondylarthropathies.
Human immunodeficiency virus type 1 escapes from interleukin-2-producing CD4+ T-cell responses without high-frequency fixation of mutations.
Maternal transmission of human immunodeficiency virus escape mutations subverts HLA-B57 immunodominance but facilitates viral control in the haploidentical infant.
Curcumin induces proapoptotic effects against human melanoma cells and modulates the cellular response to immunotherapeutic cytokines.
HLA-A01-, -A03-, and -A024-binding nanomeric epitopes in polyomavirus BK large T antigen.
Genome-wide screening of human T-cell epitopes in influenza A virus reveals a broad spectrum of CD4(+) T-cell responses to internal proteins, hemagglutinins, and neuraminidases.
CD4+ T cell responses to HLA-DP5-restricted wild-type sequence p53 peptides in patients with head and neck cancer.
Genetic modification of T cells with IL-21 enhances antigen presentation and generation of central memory tumor-specific cytotoxic T-lymphocytes.
PD1 blockade reverses the suppression of melanoma antigen-specific CTL by CD4+ CD25(Hi) regulatory T cells.
Functional effector memory T cells enrich the peritoneal cavity of patients treated with peritoneal dialysis.
Optimization of vaccine responses with an E1, E2b and E3-deleted Ad5 vector circumvents pre-existing anti-vector immunity.
The relationship between human effector and memory T cells measured by ex vivo and cultured ELISPOT following recent and distal priming.
Tumor-derived microvesicles promote regulatory T cell expansion and induce apoptosis in tumor-reactive activated CD8+ T lymphocytes.
Epitope mapping of HIV-specific CD8+ T cells in a cohort dominated by clade A1 infection.
In silico-accelerated identification of conserved and immunogenic variola/vaccinia T-cell epitopes.
Non-redundant role for IL-12 and IL-27 in modulating Th2 polarization of carcinoembryonic antigen specific CD4 T cells from pancreatic cancer patients.
Quantitating T cell cross-reactivity for unrelated peptide antigens.
Cytotoxic T lymphocyte therapy with donor T cells prevents and treats adenovirus and Epstein-Barr virus infections after haploidentical and matched unrelated stem cell transplantation.
Integrating in silico and in vitro analysis of peptide binding affinity to HLA-Cw*0102: a bioinformatic approach to the prediction of new epitopes.
Generation of Epstein-Barr virus-specific cytotoxic T lymphocytes resistant to the immunosuppressive drug tacrolimus (FK506).
Identification of major factors influencing ELISpot-based monitoring of cellular responses to antigens from Mycobacterium tuberculosis.
Ex vivo expansion of tumor specific lymphocytes with IL-15 and IL-21 for adoptive immunotherapy in melanoma.
Human follicular lymphoma CD39+-infiltrating T cells contribute to adenosine-mediated T cell hyporesponsiveness.
Functional properties and epitope characteristics of T-cells recognizing natural HIV-1 variants.
Decreased T cell reactivity to Epstein-Barr virus infected lymphoblastoid cell lines in multiple sclerosis.
Cholera caused by Vibrio cholerae O1 induces T-cell responses in the circulation.
Cell-mediated immune responses to human papillomavirus 16 E6 and E7 antigens as measured by interferon gamma enzyme-linked immunospot in women with cleared or persistent human papillomavirus infection.
Automation of the ELISpot assay for high-throughput detection of antigen-specific T-cell responses.
Detection of tuberculosis in HIV-infected children using an enzyme-linked immunospot assay.
Host immune responses to chronic adenovirus infections in human and nonhuman primates.
Decreased EBNA-1-specific CD8+ T cells in patients with Epstein-Barr virus-associated nasopharyngeal carcinoma.
HV-1-specific cytotoxic T lymphocytes and breast milk HIV-1 transmission.
ESAT-6 inhibits production of IFN-gamma by Mycobacterium tuberculosis-responsive human T cells.
MHC class I/peptide transfer between dendritic cells overcomes poor cross-presentation by monocyte-derived APCs that engulf dying cells.
NY-ESO-1 DNA vaccine induces T-cell responses that are suppressed by regulatory T cells.
Enhancing the in vivo expansion of adoptively transferred EBV-specific CTL with lymphodepleting CD45 monoclonal antibodies in NPC patients.
Reversal of human papillomavirus-specific T cell immune suppression through TLR agonist treatment of Langerhans cells exposed to human papillomavirus type 16.
Cytokine profiles and antibody responses to Plasmodium falciparum malaria infection in individuals living in Ibadan, southwest Nigeria.
Maturation pathways of dendritic cells determine TAP1 and TAP2 levels and cross-presenting function.
Interleukin-12 is the optimum cytokine to expand human Th17 cells in vitro.
Identification of C-glycoside analogues that display a potent biological activity against murine and human invariant natural killer T cells.
CD1c bypasses lysosomes to present a lipopeptide antigen with 12 amino acids.
Human T cell recognition of the blood stage antigen Plasmodium hypoxanthine guanine xanthine phosphoribosyl transferase (HGXPRT) in acute malaria.
Dynamic interaction between STLV-1 proviral load and T-cell response during chronic infection and after immunosuppression in non-human primates.
Programmed death (PD)-1 molecule and its ligand PD-L1 distribution among memory CD4 and CD8 T cell subsets in human immunodeficiency virus-1-infected individuals.
Phenotypic and functional markers for 1alpha,25-dihydroxyvitamin D(3)-modified regulatory dendritic cells.
Patients with lung cancer and paraneoplastic Hu syndrome harbor HuD-specific type 2 CD8+ T cells.
Recombinant Modified Vaccinia Ankara (MVA) effectively boosts DNA-primed HIV-specific immune responses in humans despite pre-existing vaccinia immunity.
Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen.
Enhanced systemic immune reactivity to a Basal cell carcinoma associated antigen following photodynamic therapy.
Human immunodeficiency virus-specific gamma interferon enzyme-linked immunospot assay responses targeting specific regions of the proteome during primary subtype C infection are poor predictors of the course of viremia and set point.
Human uterine NK cells interact with uterine macrophages via NKG2D upon stimulation with PAMPs.
Regulation of antigen presentation machinery in human dendritic cells by recombinant adenovirus.
Hepatitis C virus-specific T-cell immune responses in seronegative injection drug users.
In vitro evidence that commercial influenza vaccines are not similar in their ability to activate human T cell responses.
MIG (CXCL9) is a more sensitive measure than IFN-gamma of vaccine induced T-cell responses in volunteers receiving investigated malaria vaccines.
Anti-moesin antibodies in the serum of patients with aplastic anemia stimulate peripheral blood mononuclear cells to secrete TNF-alpha and IFN-gamma.
A phase I trial of a human papillomavirus DNA vaccine for HPV16+ cervical intraepithelial neoplasia 2/3.
Concordant proficiency in measurement of T-cell immunity in human immunodeficiency virus vaccine clinical trials by peripheral blood mononuclear cell and enzyme-linked immunospot assays in laboratories from three continents.
Increasing functional avidity of TCR-redirected T cells by removing defined N-glycosylation sites in the TCR constant domain.
Herpesvirus seropositivity in childhood associates with decreased monocyte-induced NK cell IFN-gamma production.
Frequencies of region of difference 1 antigen-specific but not purified protein derivative-specific gamma interferon-secreting T cells correlate with the presence of tuberculosis disease but do not distinguish recent from remote latent infections.
Melanoma-associated antigen expression in lymphangioleiomyomatosis renders tumor cells susceptible to cytotoxic T cells.
Antiviral responses following L-leucyl-L-leucine methyl esther (LLME)-treated lymphocyte infusions: graft-versus-infection without graft-versus-host disease.
HIV-1 infection impairs the bronchoalveolar T-cell response to mycobacteria.
Identification of heme oxygenase-1-specific regulatory CD8+ T cells in cancer patients.
Identification of a human cyclin D1-derived peptide that induces human cytotoxic CD4 T cells.
Minor viral and host genetic polymorphisms can dramatically impact the biologic outcome of an epitope-specific CD8 T-cell response.
Distinct roles for FOXP3 and FOXP3 CD4 T cells in regulating cellular immunity to uncomplicated and severe Plasmodium falciparum malaria.
Activated human gammadelta T cells as stimulators of specific CD8+ T-cell responses to subdominant Epstein Barr virus epitopes: potential for immunotherapy of cancer.
Multiple T-cell epitopes overlap positively-selected residues in the p1 spacer protein of HIV-1 gag.
Rituximab immunotherapy results in the induction of a lymphoma idiotype-specific T-cell response in patients with follicular lymphoma: support for a "vaccinal effect" of rituximab.
Association of HIV-specific and total CD8+ T memory phenotypes in subtype C HIV-1 infection with viral set point.
Dendritic cells based immunotherapy of patient with chondrosarcoma--case report.
Non-natural and photo-reactive amino acids as biochemical probes of immune function.
Viral load, clinical disease severity and cellular immune responses in primary varicella zoster virus infection in Sri Lanka.
Tumor-infiltrating T cells correlate with NY-ESO-1-specific autoantibodies in ovarian cancer.
In vitro study of pro-inflammatory and anti-tumour properties of microvesicles from bacterial cell wall of Pantoea agglomerans.
Identification of HLA-A*01- and HLA-A*02-restricted CD8+ T-cell epitopes shared among group B enteroviruses.
Higher homologous and lower cross-reactive Gag-specific T-cell responses in human immunodeficiency virus type 2 (HIV-2) than in HIV-1 infection.
CD4+ T helper responses in squamous cell carcinoma of the head and neck.
Inducing efficient cross-priming using antigen-coated yeast particles.
Fiber-modified recombinant adenoviral constructs encoding hepatitis C virus proteins induce potent HCV-specific T cell response.
Pilot study of diagnostic potential of the Mycobacterium tuberculosis recombinant HBHA protein in a vaccinated population in Finland.
IL-15 as memory T-cell adjuvant for topical HIV-1 DermaVir vaccine.
Expansion of human cytomegalovirus (HCMV) immediate-early 1-specific CD8+ T cells and control of HCMV replication after allogeneic stem cell transplantation.
Activation of autologous leukemia-specific T cells in acute myeloid leukemia: monocyte-derived dendritic cells cocultured with leukemic blasts compared with leukemia-derived dendritic cells.
Increased circulating paternal antigen-specific IFN-gamma- and IL-4-secreting cells during pregnancy in allergic and non-allergic women.
Studies on mRNA electroporation of immature and mature dendritic cells: effects on their immunogenic potential.
Immunization with analog peptide in combination with CpG and montanide expands tumor antigen-specific CD8+ T cells in melanoma patients.
Treatment of leber congenital amaurosis due to RPE65 mutations by ocular subretinal injection of adeno-associated virus gene vector: short-term results of a phase I trial.
The intracellular detection of MIP-1beta enhances the capacity to detect IFN-gamma mediated HIV-1-specific CD8 T-cell responses in a flow cytometric setting providing a sensitive alternative to the ELISPOT.
Effects of recombinant human growth hormone on HIV-1-specific T-cell responses, thymic output and proviral DNA in patients on HAART: 48-week follow-up.
Dynamics of human respiratory virus-specific CD8+ T cell responses in blood and airways during episodes of common cold.
T cell responses to whole SARS coronavirus in humans.
Generation of HIV-1-specific CD8+ cell responses following allogeneic hematopoietic cell transplantation.
Resting regulatory CD4 T cells: a site of HIV persistence in patients on long-term effective antiretroviral therapy.
A comparison of IFNgamma detection methods used in tuberculosis vaccine trials.
Host ethnicity and virus genotype shape the hepatitis B virus-specific T-cell repertoire.
Enhancement of human immunodeficiency virus (HIV)-specific CD8+ T cells in cerebrospinal fluid compared to those in blood among antiretroviral therapy-naive HIV-positive subjects.
Optimizing peptide matrices for identifying T-cell antigens.
Urea-mediated cross-presentation of soluble Epstein-Barr virus BZLF1 protein.
Identification of an immunodominant region of Fel d 1 and characterization of constituent epitopes.
Improved cell mediated immune responses after successful re-vaccination of non-responders to the hepatitis B virus surface antigen (HBsAg) vaccine using the combined hepatitis A and B vaccine.
Immunodominant epitopes in herpes simplex virus type 2 glycoprotein D are recognized by CD4 lymphocytes from both HSV-1 and HSV-2 seropositive subjects.
Functional impairment of cytomegalovirus specific CD8 T cells predicts high-level replication after renal transplantation.
Immunogenicity of human mesenchymal stem cells in HLA-class I-restricted T-cell responses against viral or tumor-associated antigens.
A novel, helminth-derived immunostimulant enhances human recall responses to hepatitis C virus and tetanus toxoid and is dependent on CD56+ cells for its action.
Antigen load and viral sequence diversification determine the functional profile of HIV-1-specific CD8+ T cells.
Comprehensive analysis of west nile virus-specific T cell responses in humans.
Results and harmonization guidelines from two large-scale international Elispot proficiency panels conducted by the Cancer Vaccine Consortium (CVC/SVI).
Regression of human kidney cancer following allogeneic stem cell transplantation is associated with recognition of an HERV-E antigen by T cells.
Improved diagnostic evaluation of suspected tuberculosis.
Allogeneic granulocyte macrophage colony-stimulating factor-secreting tumor immunotherapy alone or in sequence with cyclophosphamide for metastatic pancreatic cancer: a pilot study of safety, feasibility, and immune activation.
Varicella zoster virus glycoprotein E-specific CD4+ T cells show evidence of recent activation and effector differentiation, consistent with frequent exposure to replicative cycle antigens in healthy immune donors.
Clinical phase 1 testing of the safety and immunogenicity of an epitope-based DNA vaccine in human immunodeficiency virus type 1-infected subjects receiving highly active antiretroviral therapy.
Memory T cells specific for novel human papillomavirus type 16 (HPV16) E6 epitopes in women whose HPV16 infection has become undetectable.
The Src/ABL kinase inhibitor dasatinib (BMS-354825) inhibits function of normal human T-lymphocytes in vitro.
Rapid diagnosis of Mycobacterium tuberculosis meningitis by enumeration of cerebrospinal fluid antigen-specific T-cells.
Identification of immunogenic HLA-B7 "Achilles' heel" epitopes within highly conserved regions of HIV.
Intrahepatic CD8(+) lymphocyte trapping during tolerance induction using mushroom derived formulations: a possible role for liver in tolerance induction.
Comparison of alpha-Type-1 polarizing and standard dendritic cell cytokine cocktail for maturation of therapeutic monocyte-derived dendritic cell preparations from cancer patients.
Treatment of metastatic melanoma with autologous CD4+ T cells against NY-ESO-1.
Development and dynamics of robust T-cell responses to CML under imatinib treatment.
Identification of HLA-A2 restricted T-cell epitopes within the conserved region of the immunoglobulin G heavy-chain in patients with multiple myeloma.
Heterosubtypic T-cell responses against avian influenza H5 haemagglutinin are frequently detected in individuals vaccinated against or previously infected with human subtypes of influenza.
Evaluation of immune responses to seasonal influenza vaccination in healthy volunteers and in patients after stem cell transplantation.
CD4-specific designed ankyrin repeat proteins are novel potent HIV entry inhibitors with unique characteristics.
Cross-subtype antibody and cellular immune responses induced by a polyvalent DNA prime-protein boost HIV-1 vaccine in healthy human volunteers.
Poor immunogenicity of BCG in helminth infected population is associated with increased in vitro TGF-beta production.
Humoral and cellular response to influenza vaccine in HIV-infected children with full viroimmunologic response to antiretroviral therapy.
Immunization of malignant melanoma patients with full-length NY-ESO-1 protein using TLR7 agonist imiquimod as vaccine adjuvant.
Hepatitis B virus e antigen loss during adefovir dipivoxil therapy is associated with enhanced virus-specific CD4+ T-cell reactivity.
The lipophilic hapten parthenolide induces interferon-gamma and interleukin-13 production by peripheral blood-derived CD8+ T cells from contact allergic subjects in vitro.
Therapeutic vaccination with a trivalent T-cell receptor (TCR) peptide vaccine restores deficient FoxP3 expression and TCR recognition in subjects with multiple sclerosis.
A phase I clinical study of vaccination of melanoma patients with dendritic cells loaded with allogeneic apoptotic/necrotic melanoma cells. Analysis of toxicity and immune response to the vaccine and of IL-10 -1082 promoter genotype as predictor of disease progression.
Increased antigen presentation efficiency by coupling antigens to MHC class I trafficking signals.
Induction of tumor-specific CD4+ and CD8+ T-cell immunity in cervical cancer patients by a human papillomavirus type 16 E6 and E7 long peptides vaccine.
Mannose-capped lipoarabinomannan- and prostaglandin E2-dependent expansion of regulatory T cells in human Mycobacterium tuberculosis infection.
Peptide impurities in commercial synthetic peptides and their implications for vaccine trial assessment.
Tonsilar NK cells restrict B cell transformation by the Epstein-Barr virus via IFN-gamma.
Cross-subtype antibody and cellular immune responses induced by a polyvalent DNA prime-protein boost HIV-1 vaccine in healthy human volunteers.
Major histocompatibility complex class I cytotoxic T lymphocyte immunity to human metapneumovirus (hMPV) in individuals with previous hMPV infection and respiratory disease.
Induction of regulatory T cell-resistant helper CD4+ T cells by bacterial vector.
Vaccinia virus-specific CD8(+) T-cell responses target a group of epitopes without a strong immunodominance hierarchy in humans.
RhoC a new target for therapeutic vaccination against metastatic cancer.
Lack of an inverse association between tuberculosis infection and atopy: by T-cell-based immune assay (RD1-ELISpot).
Evaluation of antigen-specific T-cell responses with a miniaturized and automated method.
Safety and immunogenicity of recombinant poxvirus HIV-1 vaccines in young adults on highly active antiretroviral therapy.
Lessons from IAVI-006, a phase I clinical trial to evaluate the safety and immunogenicity of the pTHr.HIVA DNA and MVA.HIVA vaccines in a prime-boost strategy to induce HIV-1 specific T-cell responses in healthy volunteers.
Naturally acquired humoral and cellular immune responses to Plasmodium vivax merozoite surface protein 9 in Northwestern Amazon individuals.
T cell responses to mycobacterial catalase-peroxidase profile a pathogenic antigen in systemic sarcoidosis.
Transduction with the antioxidant enzyme catalase protects human T cells against oxidative stress.
Mechanisms of HIV non-progression; robust and sustained CD4+ T-cell proliferative responses to p24 antigen correlate with control of viraemia and lack of disease progression after long-term transfusion-acquired HIV-1 infection.
Nadir CD4 T-cell counts continue to influence interferon-gamma responses in HIV patients who began antiretroviral treatment with advanced immunodeficiency.
CD4+ T helper cell responses against human bocavirus viral protein 2 viruslike particles in healthy adults.
Deficiency of HIV-Gag-specific T cells in early childhood correlates with poor viral containment.
Transmission of human immunodeficiency virus type 1 from a patient who developed AIDS to an elite suppressor.
Analysis of the cellular immune response in patients with the digestive and indeterminate forms of Chagas' disease.
Recognition of naturally processed and ovarian cancer reactive CD8+ T cell epitopes within a promiscuous HLA class II T-helper region of NY-ESO-1.
Immunologic response to primary cryoablation of high-risk prostate cancer.
Leishmania surface protein gp63 binds directly to human natural killer cells and inhibits proliferation.
Influenza virus vaccination induces interleukin-12/23 receptor beta 1 (IL-12/23R beta 1)-independent production of gamma interferon (IFN-gamma) and humoral immunity in patients with genetic deficiencies in IL-12/23R beta 1 or IFN-gamma receptor I.
The number and function of circulating dendritic cells may limit effector memory CD4+ T-cell responses in HIV patients responding to antiretroviral therapy.
Maintenance of large subpopulations of differentiated CD8 T-cells two years after cytomegalovirus infection in Gambian infants.
EBNA1-specific T cells from patients with multiple sclerosis cross react with myelin antigens and co-produce IFN-gamma and IL-2.
Beneficial effect of TRAIL on HIV burden, without detectable immune consequences.
Safety and immunogenicity of a new tuberculosis vaccine, MVA85A, in healthy adults in South Africa.
Immunosuppressive effect of isopropanol: down-regulation of cytokine production results from the alteration of discrete transcriptional pathways in activated lymphocytes.
The Wilms' tumor antigen is a novel target for human CD4+ regulatory T cells: implications for immunotherapy.
Optimal blood mononuclear cell isolation procedures for gamma interferon enzyme-linked immunospot testing of healthy Swedish and Tanzanian subjects.
Different types of in vitro generated human monocyte-derived dendritic cells release exosomes with distinct phenotypes.
Correlation of memory T cell responses against TRAP with protection from clinical malaria, and CD4 CD25 high T cells with susceptibility in Kenyans.
Superoxide dismutase A antigens derived from molecular analysis of sarcoidosis granulomas elicit systemic Th-1 immune responses.
Impact of clonal competition for peptide-MHC complexes on the CD8+ T-cell repertoire selection in a persistent viral infection.
Detection of polyfunctional Mycobacterium tuberculosis-specific T cells and association with viral load in HIV-1-infected persons.
Broadly immunogenic HLA class I supertype-restricted elite CTL epitopes recognized in a diverse population infected with different HIV-1 subtypes.
Differential functional avidity of dengue virus-specific T-cell clones for variant peptides representing heterologous and previously encountered serotypes.
Extensive HLA class I allele promiscuity among viral CTL epitopes.
The induction and persistence of T cell IFN-gamma responses after vaccination or natural exposure is suppressed by Plasmodium falciparum.
High T-cell response to human cytomegalovirus induces chemokine-mediated endothelial cell damage.
Toward the development of multi-epitope p53 cancer vaccines: an in vitro assessment of CD8(+) T cell responses to HLA class I-restricted wild-type sequence p53 peptides.
Robust Gag-specific T cell responses characterize viremia control in HIV-2 infection.
Numerical and functional defects of blood dendritic cells in early- and late-stage breast cancer.
Immunological control of chronic HIV-1 infection: HLA-mediated immune function and viral evolution in adolescents.
A viral CTL escape mutation leading to immunoglobulin-like transcript 4-mediated functional inhibition of myelomonocytic cells.
Enhanced detection of human immunodeficiency virus type 1 (HIV-1) Nef-specific T cells recognizing multiple variants in early HIV-1 infection.
Hepatitis B virus splice-generated protein induces T-cell responses in HLA-transgenic mice and hepatitis B virus-infected patients.
Phase I dose escalation safety and immunogenicity trial of Plasmodium falciparum apical membrane protein (AMA-1) FMP2.1, adjuvanted with AS02A, in malaria-naïve adults at the Walter Reed Army Institute of Research.
The length of lipids bound to human CD1d molecules modulates the affinity of NKT cell TCR and the threshold of NKT cell activation.
Cytokine responses in acute and persistent human parvovirus B19 infection.
CD8 tumor-infiltrating lymphocytes are predictive of survival in muscle-invasive urothelial carcinoma.
A dual color ELISPOT method for the simultaneous detection of IL-2 and IFN-gamma HIV-specific immune responses.
Fully differentiated HIV-1 specific CD8+ T effector cells are more frequently detectable in controlled than in progressive HIV-1 infection.
HIV patients developing primary CNS lymphoma lack EBV-specific CD4+ T cell function irrespective of absolute CD4+ T cell counts.
Bacterial superantigen facilitates epithelial presentation of allergen to T helper 2 cells.
Facilitating matched pairing and expression of TCR chains introduced into human T cells.
Cytomegalovirus infection in Gambian infants leads to profound CD8 T-cell differentiation.
T-cell recognition of the HspX protein of Mycobacterium tuberculosis correlates with latent M. tuberculosis infection but not with M. bovis BCG vaccination.
Human infant respiratory syncytial virus (RSV)-specific type 1 and 2 cytokine responses ex vivo during primary RSV infection.
Availability of a diversely avid CD8+ T cell repertoire specific for the subdominant HLA-A2-restricted HIV-1 Gag p2419-27 epitope.
Recognition of a defined region within p24 gag by CD8+ T cells during primary human immunodeficiency virus type 1 infection in individuals expressing protective HLA class I alleles.
Direct comparison of antigen production and induction of apoptosis by canarypox virus- and modified vaccinia virus ankara-human immunodeficiency virus vaccine vectors.
Mycobacterium tuberculosis Antigen 85A induces Th-1 immune responses in systemic sarcoidosis.
Tracking virus-specific CD4+ T cells during and after acute hepatitis C virus infection.
Antigen-loading compartments for major histocompatibility complex class II molecules continuously receive input from autophagosomes.
Decreased up-regulation of the interleukin-12Rbeta2-chain and interferon-gamma secretion and increased number of forkhead box P3-expressing cells in patients with a history of chronic Lyme borreliosis compared with asymptomatic Borrelia-exposed individuals.
Substantial improvements in performance indicators achieved in a peripheral blood mononuclear cell cryopreservation quality assurance program using single donor samples.
Mutually exclusive T-cell receptor induction and differential susceptibility to human immunodeficiency virus type 1 mutational escape associated with a two-amino-acid difference between HLA class I subtypes.
HLA class I binding promiscuity of the CD8 T-cell epitopes of human papillomavirus type 16 E6 protein.
Proteasome-independent major histocompatibility complex class I cross-presentation mediated by papaya mosaic virus-like particles leads to expansion of specific human T cells.
Genomic analysis of HIV type 1 strains derived from a mother and child pair of long-term nonprogressors.
Combined therapy of transcatheter hepatic arterial embolization with intratumoral dendritic cell infusion for hepatocellular carcinoma: clinical safety.
MUC1-specific immune therapy generates a strong anti-tumor response in a MUC1-tolerant colon cancer model.
Phase 2 study of an HIV-1 canarypox vaccine (vCP1452) alone and in combination with rgp120: negative results fail to trigger a phase 3 correlates trial.
Distinct memory CD4+ T-cell subsets mediate immune recognition of Epstein Barr virus nuclear antigen 1 in healthy virus carriers.
Human immunodeficiency virus-specific CD8+ T-cell activity is detectable from birth in the majority of in utero-infected infants.
Multiple Mycobacterium antigens induce interferon-gamma production from sarcoidosis peripheral blood mononuclear cells.
Rapid diagnosis of smear-negative tuberculosis using immunology and microbiology with induced sputum in HIV-infected and uninfected individuals.
A phase I pilot study of autologous heat shock protein vaccine HSPPC-96 in patients with resected pancreatic adenocarcinoma.
Cross-reactive T-cell responses to the nonstructural regions of dengue viruses among dengue fever and dengue hemorrhagic fever patients in Malaysia.
Human polyomavirus type 1 (BK virus) agnoprotein is abundantly expressed but immunologically ignored.
Human immunodeficiency virus type 1 specific cytotoxic T lymphocyte responses in Chinese infected with HIV-1 B'/C Recombinant (CRF07_BC).
Utility of interferon-gamma ELISPOT assay responses in highly tuberculosis-exposed patients with advanced HIV infection in South Africa.
Human CD8+ T cell memory generation in Puumala hantavirus infection occurs after the acute phase and is associated with boosting of EBV-specific CD8+ memory T cells.
Characterization of hepatitis B virus (HBV)-specific T-cell dysfunction in chronic HBV infection.
Evaluation of alloreactivity in responder-stimulator pairs by determination of gamma interferon-producing cells and cytotoxic-T-lymphocyte precursor frequencies.
Detection of human papillomavirus type 16-specific T lymphocytes by a recombinant vaccinia virus-based enzyme-linked immunospot assay.
Diagnosis of tuberculosis by an enzyme-linked immunospot assay for interferon-gamma.
CD4+ CD25+ regulatory T cells in human pregnancy: development of a Treg-MLC-ELISPOT suppression assay and indications of paternal specific Tregs.
CD4+ T cell targeting of human immunodeficiency virus type 1 (HIV-1) peptide sequences present in vivo during chronic, progressive HIV-1 disease.
Immunization with HIV protease peptides linked to syngeneic erythrocytes.
Splenic accumulation of IL-10 mRNA in T cells distinct from CD4+CD25+ (Foxp3) regulatory T cells in human visceral leishmaniasis.
HLA-DQB1*02-restricted HPV-16 E7 peptide-specific CD4+ T-cell immune responses correlate with regression of HPV-16-associated high-grade squamous intraepithelial lesions.
Generation of clinical grade dendritic cells with capacity to produce biologically active IL-12p70.
A phase I, randomized study of combined IL-2 and therapeutic immunisation with antiretroviral therapy.
Pilot phase III immunotherapy study in early-stage breast cancer patients using oxidized mannan-MUC1 [ISRCTN71711835].
Down-regulation of interferon-gamma parallels clinical response to selective leukocyte apheresis in patients with inflammatory bowel disease: a 12-month follow-up study.
A reproducible method for the enumeration of functional (cytokine producing) versus non-functional peptide-specific cytotoxic T lymphocytes in human peripheral blood.
A T2 cytokine environment may not limit T1 responses in human immunodeficiency virus patients with a favourable response to antiretroviral therapy.
HLA-A24 and survivin: possibilities in therapeutic vaccination against cancer.
Adoptive immunotherapy with allodepleted donor T-cells improves immune reconstitution after haploidentical stem cell transplantation.
Human T-cell responses to vaccinia virus envelope proteins.
Persistent high frequencies of varicella-zoster virus ORF4 protein-specific CD4+ T cells after primary infection.
Tumor mRNA-transfected dendritic cells stimulate the generation of CTL that recognize neuroblastoma-associated antigens and kill tumor cells: immunotherapeutic implications.
A phase 2b randomised trial of the candidate malaria vaccines FP9 ME-TRAP and MVA ME-TRAP among children in Kenya.
Early gamma interferon and interleukin-2 responses to vaccination predict the late resting memory in malaria-naïve and malaria-exposed individuals.
The highly attenuated vaccinia virus strain modified virus Ankara induces apoptosis in melanoma cells and allows bystander dendritic cells to generate a potent anti-tumoral immunity.
The polycomb group proteins, BMI-1 and EZH2, are tumour-associated antigens.
Treatment of solid organ transplant recipients with autologous Epstein Barr virus-specific cytotoxic T lymphocytes (CTLs).
Induction of multifunctional human immunodeficiency virus type 1 (HIV-1)-specific T cells capable of proliferation in healthy subjects by using a prime-boost regimen of DNA- and modified vaccinia virus Ankara-vectored vaccines expressing HIV-1 Gag coupled to CD8+ T-cell epitopes.
The 6-kilodalton early secreted antigenic target-responsive, asymptomatic contacts of tuberculosis patients express elevated levels of interleukin-4 and reduced levels of gamma interferon.
Identification of a major histocompatibility complex class I-restricted T-cell epitope in the tumour-associated antigen, 5T4.
Elicitation from virus-naive individuals of cytotoxic T lymphocytes directed against conserved HIV-1 epitopes.
Maintenance of viral suppression in HIV-1-infected HLA-B*57+ elite suppressors despite CTL escape mutations.
Natural killer cell function is well preserved in asymptomatic human immunodeficiency virus type 2 (HIV-2) infection but similar to that of HIV-1 infection when CD4 T-cell counts fall.
Antagonism of HIV-specific CD4+ T cells by C-terminal truncation of a minimum epitope.
Fluctuations of functionally distinct CD8+ T-cell clonotypes demonstrate flexibility of the HIV-specific TCR repertoire.
The hypervariable immunodominant NP418-426 epitope from the influenza A virus nucleoprotein is recognized by cytotoxic T lymphocytes with high functional avidity.
Diversity of the CD8+ T-cell response to herpes simplex virus type 2 proteins among persons with genital herpes.
Relationship between maternal and child cytokine responses to allergen and phytohaemagglutinin 2 years after delivery.
Evaluation of the interlaboratory concordance in quantification of human immunodeficiency virus-specific T cells with a gamma interferon enzyme-linked immunospot assay.
Lyme borreliosis reinfection: might it be explained by a gender difference in immune response?
Rectal nitric oxide as biomarker in the treatment of inflammatory bowel disease: responders versus nonresponders.
Passive sexual transmission of human immunodeficiency virus type 1 variants and adaptation in new hosts.
In vivo antigen delivery by a Salmonella typhimurium type III secretion system for therapeutic cancer vaccines.
Characterization of the IFN-gamma T-cell responses to immediate early antigens in humans with genital herpes.
Rapid qualitative and quantitative analysis of T-cell responses in HIV-1-infected individuals receiving successful HAART and HIV-1 sero-negative controls: concomitant assessment of perforin, IFN-gamma and IL-4 secretion.
Control of human immunodeficiency virus replication by cytotoxic T lymphocytes targeting subdominant epitopes.
Reduced number of interleukin-12 secreting cells in patients with Lyme borreliosis previously exposed to Anaplasma phagocytophilum.
Recognition of stage-specific mycobacterial antigens differentiates between acute and latent infections with Mycobacterium tuberculosis.
Engagement of CD83 ligand induces prolonged expansion of CD8+ T cells and preferential enrichment for antigen specificity.
Protein vaccines induce uncommitted IL-2-secreting human and mouse CD4 T cells, whereas infections induce more IFN-gamma-secreting cells.
Tumor infiltrating T lymphocytes in colorectal cancer: Tumor-selective activation and cytotoxic activity in situ.
Combinations of common chronic paediatric diseases deviate the immune response in diverging directions.
Nickel, cobalt, chromium, palladium and gold induce a mixed Th1- and Th2-type cytokine response in vitro in subjects with contact allergy to the respective metals.
Large scale analysis of pediatric antiviral CD8+ T cell populations reveals sustained, functional and mature responses.
CD4+CD25+FOXP3+ regulatory T cells suppress anti-tumor immune responses in patients with colorectal cancer.
The apoptotic-cell receptor CR3, but not alphavbeta5, is a regulator of human dendritic-cell immunostimulatory function.
Antagonists and non-toxic variants of the dominant wheat gliadin T cell epitope in coeliac disease.
Identification of a new HLA-A2-restricted T-cell epitope within HM1.24 as immunotherapy target for multiple myeloma.
Evaluation of adenovirus vectors containing serotype 35 fibers for vaccination.
CTL epitope distribution patterns in the Gag and Nef proteins of HIV-1 from subtype A infected subjects in Kenya: use of multiple peptide sets increases the detectable breadth of the CTL response.
Peripheral blood but not synovial fluid natural killer T cells are biased towards a Th1-like phenotype in rheumatoid arthritis.
Sustained CD8+ T-cell responses induced after acute parvovirus B19 infection in humans.
Broad cross-clade T-cell responses to gag in individuals infected with human immunodeficiency virus type 1 non-B clades (A to G): importance of HLA anchor residue conservation.
Functional constraints of influenza A virus epitopes limit escape from cytotoxic T lymphocytes.
Pulmonary interleukin-23 gene delivery increases local T-cell immunity and controls growth of Mycobacterium tuberculosis in the lungs.
Nickel elicits concomitant and correlated in vitro production of Th1-, Th2-type and regulatory cytokines in subjects with contact allergy to nickel.
Modified vaccinia Ankara expressing HIVA antigen stimulates HIV-1-specific CD8 T cells in ELISpot assays of HIV-1 exposed infants.
T cell reactivity to P0, P2, PMP-22, and myelin basic protein in patients with Guillain-Barre syndrome and chronic inflammatory demyelinating polyradiculoneuropathy.
Reduced frequency of FOXP3+ CD4+CD25+ regulatory T cells in patients with chronic graft-versus-host disease.
Cytokine serum levels in patients infected by human immunodeficiency virus with and without Trypanosoma cruzi coinfection.
The immunogenicity of a viral cytotoxic T cell epitope is controlled by its MHC-bound conformation.
Live attenuated yellow fever 17D infects human DCs and allows for presentation of endogenous and recombinant T cell epitopes.
Enzyme-linked immunospot and tuberculin skin testing to detect latent tuberculosis infection.
Early T-cell responses to dengue virus epitopes in Vietnamese adults with secondary dengue virus infections.
Cross-reactive cytotoxic T lymphocytes against human immunodeficiency virus type 1 protease and gamma interferon-inducible protein 30.
Efficient Ex vivo stimulation of Mycobacterium tuberculosis-specific T cells by genetically detoxified Bordetella pertussis adenylate cyclase antigen toxoids.
Schistosoma infection inhibits cellular immune responses to core HCV peptides.
Hepatitis B surface antigen presentation and HLA-DRB1*- lessons from twins and peptide binding studies.
Identification of a new HLA-A*0201-restricted CD8+ T cell epitope from hepatocellular carcinoma-associated antigen HCA587.
Oral immune regulation using colitis extracted proteins for treatment of Crohn's disease: results of a phase I clinical trial.
Sustained expansion of NKT cells and antigen-specific T cells after injection of alpha-galactosyl-ceramide loaded mature dendritic cells in cancer patients.
Simultaneous assessment of cytotoxic T lymphocyte responses against multiple viral infections by combined usage of optimal epitope matrices, anti- CD3 mAb T-cell expansion and "RecycleSpot".
Processing and presentation of exogenous HLA class I peptides by dendritic cells from human immunodeficiency virus type 1-infected persons.
MyD88 expression is required for efficient cross-presentation of viral antigens from infected cells.
Vaccination of metastatic melanoma patients with autologous dendritic cell (DC) derived-exosomes: results of thefirst phase I clinical trial.
Repertoire, diversity, and differentiation of specific CD8 T cells are associated with immune protection against human cytomegalovirus disease.
Recognition of six-transmembrane epithelial antigen of the prostate-expressing tumor cells by peptide antigen-induced cytotoxic T lymphocytes.
Longitudinal assessment of human immunodeficiency virus type 1 (HIV-1)-specific gamma interferon responses during the first year of life in HIV-1-infected infants.
Human immunodeficiency virus type 1 Vpr impairs dendritic cell maturation and T-cell activation: implications for viral immune escape.
Innate immune responses in Lyme borreliosis: enhanced tumour necrosis factor-alpha and interleukin-12 in asymptomatic individuals in response to live spirochetes.
T-cell responses to human papillomavirus type 16 among women with different grades of cervical neoplasia.
The bisphosphonate acute phase response: rapid and copious production of proinflammatory cytokines by peripheral blood gd T cells in response to aminobisphosphonates is inhibited by statins.
Clinical response in Japanese metastatic melanoma patients treated with peptide cocktail-pulsed dendritic cells.
T cell response to Hu-D peptides in patients with anti-Hu syndrome.
CD8+ immunodominance among Epstein-Barr virus lytic cycle antigens directly reflects the efficiency of antigen presentation in lytically infected cells.
Selective blockade of inhibitory Fcgamma receptor enables human dendritic cell maturation with IL-12p70 production and immunity to antibody-coated tumor cells.
Antigen expression kinetics and immune responses of mice immunized with noninfectious simian-human immunodeficiency virus DNA.
HLA-DR+ immature cells exhibit reduced antigen-presenting cell function but respond to CD40 stimulation.
A population of HLA-DR+ immature cells accumulates in the blood dendritic cell compartment of patients with different types of cancer.
Dendritic cell immunizations alone or combined with low doses of interleukin-2 induce specific immune responses in melanoma patients.
Cross-reactive influenza virus-specific CD8+ T cells contribute to lymphoproliferation in Epstein-Barr virus-associated infectious mononucleosis.
HLA-B63 presents HLA-B57/B58-restricted cytotoxic T-lymphocyte epitopes and is associated with low human immunodeficiency virus load.
Cytokine expression in pediatric Helicobacter pylori infection.
Human immunodeficiency virus (HIV)-specific gamma interferon secretion directed against all expressed HIV genes: relationship to rate of CD4 decline.
Human immunodeficiency virus-specific responses in adult Ugandans: patterns of cross-clade recognition.
Mycobacterium tuberculosis genome-wide screen exposes multiple CD8 T cell epitopes.
CD25brightCD4+ regulatory T cells are enriched in inflamed joints of patients with chronic rheumatic disease.
Impaired IFN-gamma production by viral immunodominant peptide-specific tetramer+ CD8+ T cells in HIV-1 infected patients is not secondary to HAART.
A hairpin turn in a class II MHC-bound peptide orients residues outside the binding groove for T cell recognition.
Loss of HIV-1-specific CD8+ T cell proliferation after acute HIV-1 infection and restoration by vaccine-induced HIV-1-specific CD4+ T cells.
IFN-gamma enables cross-presentation of exogenous protein antigen in human Langerhans cells by potentiating maturation.
Human immunodeficiency virus type 1 (HIV-1)-specific CD4+ T cells that proliferate in vitro detected in samples from most viremic subjects and inversely associated with plasma HIV-1 levels.
Multispecific T cell response and negative HCV RNA tests during acute HCV infection are early prognostic factors of spontaneous clearance.
Detecting specific cytotoxic T lymphocytes against SARS-coronavirus with DimerX HLA-A2:Ig fusion protein.
Limited durability of viral control following treated acute HIV infection.
A randomised, double-blind, controlled vaccine efficacy trial of DNA/MVA ME-TRAP against malaria infection in Gambian adults.
Determinants of human immunodeficiency virus type 1 escape from the primary CD8+ cytotoxic T lymphocyte response.
Evaluation of T-cell responses to novel RD1- and RD2-encoded Mycobacterium tuberculosis gene products for specific detection of human tuberculosis infection.
Gender-related cytokine patterns in sera of schistosomiasis patients with Symmers' fibrosis.
CD8+ T lymphocyte responses target functionally important regions of Protease and Integrase in HIV-1 infected subjects.
Consistent cytotoxic-T-lymphocyte targeting of immunodominant regions in human immunodeficiency virus across multiple ethnicities.
T-cell epitopes in severe acute respiratory syndrome (SARS) coronavirus spike protein elicit a specific T-cell immune response in patients who recover from SARS.
Toll-like receptor 4 expression and cytokine responses in the human urinary tract mucosa.
Recognition of nonpeptide antigens by human V gamma 9V delta 2 T cells requires contact with cells of human origin.
Individual RD1-region genes are required for export of ESAT-6/CFP-10 and for virulence of Mycobacterium tuberculosis.
Identification of a common HLA-DP4-restricted T-cell epitope in the conserved region of the respiratory syncytial virus G protein.
IL-12 enhances the generation of tumour antigen-specific Th1 CD4 T cells during ex vivo expansion.
Cellular immunity induced by the recombinant Plasmodium falciparum malaria vaccine, RTS,S/AS02, in semi-immune adults in The Gambia.
Comparison of human immunodeficiency virus (HIV)-specific T-cell responses in HIV-1- and HIV-2-infected individuals in Senegal.
Functional regulatory immune responses against human cartilage glycoprotein-39 in health vs. proinflammatory responses in rheumatoid arthritis.
T cell cross-reactivity and conformational changes during TCR engagement.
Cytotoxic T lymphocyte therapy for Epstein-Barr virus+ Hodgkin's disease.
Frequent transmission of cytotoxic-T-lymphocyte escape mutants of human immunodeficiency virus type 1 in the highly HLA-A24-positive Japanese population.
Increased expression of mRNA encoding interleukin (IL)-4 and its splice variant IL-4delta2 in cells from contacts of Mycobacterium tuberculosis, in the absence of in vitro stimulation.
Mesothelin-specific CD8(+) T cell responses provide evidence of in vivo cross-priming by antigen-presenting cells in vaccinated pancreatic cancer patients.
A phase I trial of DNA vaccination with a plasmid expressing prostate-specific antigen in patients with hormone-refractory prostate cancer.
Hierarchical targeting of subtype C human immunodeficiency virus type 1 proteins by CD8+ T cells: correlation with viral load.
Minor histocompatibility antigen DBY elicits a coordinated B and T cell response after allogeneic stem cell transplantation.
High levels of interleukin-1 in patients with endemic pemphigus foliaceus.
Long-term specific immune responses induced in humans by a human immunodeficiency virus type 1 lipopeptide vaccine: characterization of CD8+-T-cell epitopes recognized.
Productive infection maintains a dynamic steady state of residual viremia in human immunodeficiency virus type 1-infected persons treated with suppressive antiretroviral therapy for five years.
Yeast-derived human immunodeficiency virus type 1 p55(gag) virus-like particles activate dendritic cells (DCs) and induce perforin expression in Gag-specific CD8(+) T cells by cross-presentation of DCs.
Over-expression of interleukin 10 in mucosal T cells of patients with active ulcerative colitis.
Vaccination of recurrent glioma patients with tumour lysate-pulsed dendritic cells elicits immune responses: results of a clinical phase I/II trial.
Ex vivo profiling of CD8+-T-cell responses to human cytomegalovirus reveals broad and multispecific reactivities in healthy virus carriers.
Evaluation of amastigote reactive cells in human cutaneous leishmaniasis caused by Leishmania aethiopica.
Tolerogenic immunosuppression for organ transplantation.
Live Leishmania promastigotes can directly activate primary human natural killer cells to produce interferon-gamma.
Melanoma inhibitor of apoptosis protein (ML-IAP) is a target for immune-mediated tumor destruction.
Comprehensive analysis of human immunodeficiency virus type 1 (HIV-1)-specific gamma interferon-secreting CD8+ T cells in primary HIV-1 infection.
Mature CD8(+) T lymphocyte response to viral infection during fetal life.
Comprehensive screening reveals strong and broadly directed human immunodeficiency virus type 1-specific CD8 responses in perinatally infected children.
Ex vivo analysis of T-cell responses to Epstein-Barr virus-encoded oncogene latent membrane protein 1 reveals highly conserved epitope sequences in virus isolates from diverse geographic regions.
Enhanced detection of human immunodeficiency virus type 1-specific T-cell responses to highly variable regions by using peptides based on autologous virus sequences.
Respiratory syncytial virus nucleoprotein-specific cytotoxic T-cell epitopes in a South African population of diverse HLA types are conserved in circulating field strains.
Murine cytomegalovirus abortively infects human dendritic cells, leading to expression and presentation of virally vectored genes.
Survey of naturally occurring CD4+ T cell responses against NY-ESO-1 in cancer patients: correlation with antibody responses.
Identification of immunodominant epitopes derived from the respiratory syncytial virus fusion protein that are recognized by human CD4 T cells.
Association between virus-specific T-cell responses and plasma viral load in human immunodeficiency virus type 1 subtype C infection.
Avenin fails to induce a Th1 response in coeliac tissue following in vitro culture.
T cell vaccination in multiple sclerosis patients with autologous CSF-derived activated T cells: results from a pilot study.
Decreased epithelial cytokine responses in the duodenal mucosa of Helicobacter pylori-infected duodenal ulcer patients.
Early induction and maintenance of Env-specific T-helper cells following human immunodeficiency virus type 1 infection.
Comprehensive epitope analysis of human immunodeficiency virus type 1 (HIV-1)-specific T-cell responses directed against the entire expressed HIV-1 genome demonstrate broadly directed responses, but no correlation to viral load.
HLA class II polymorphisms and susceptibility to recurrent respiratory papillomatosis.
Identification of sequential viral escape mutants associated with altered T-cell responses in a human immunodeficiency virus type 1-infected individual.
Vigorous but short-term gamma interferon T-cell responses against a dominant HLA-A*02-restricted measles virus epitope in patients with measles.
Kaposi's sarcoma-associated herpesvirus cytotoxic T lymphocytes recognize and target Darwinian positively selected autologous K1 epitopes.
Identification of a novel human leucocyte antigen-A*01-restricted cytotoxic T-lymphocyte epitope in the respiratory syncytial virus fusion protein.
A balanced type 1/type 2 response is associated with long-term nonprogressive human immunodeficiency virus type 1 infection.
Consistent patterns in the development and immunodominance of human immunodeficiency virus type 1 (HIV-1)-specific CD8+ T-cell responses following acute HIV-1 infection.
CD8(+) T cell responses against a dominant cryptic HLA-A2 epitope after NY-ESO-1 peptide immunization of cancer patients.
Disease-associated bias in T helper type 1 (Th1)/Th2 CD4(+) T cell responses against MAGE-6 in HLA-DRB10401(+) patients with renal cell carcinoma or melanoma.
Study of antigen-processing steps reveals preferences explaining differential biological outcomes of two HLA-A2-restricted immunodominant epitopes from human immunodeficiency virus type 1.
Magnitude and frequency of cytotoxic T-lymphocyte responses: identification of immunodominant regions of human immunodeficiency virus type 1 subtype C.
Oral immunization with a Salmonella enterica serovar typhi vaccine induces specific circulating mucosa-homing CD4(+) and CD8(+) T cells in humans.
Response of in vivo protein synthesis in T lymphocytes and leucocytes to an endotoxin challenge in healthy volunteers.
Allergen-specific CD8(+) T cells and atopic disease.
Comprehensive screening for human immunodeficiency virus type 1 subtype-specific CD8 cytotoxic T lymphocytes and definition of degenerate epitopes restricted by HLA-A0207 and -C(W)0304 alleles.
Identification and characterization of the ESAT-6 homologue of Mycobacterium leprae and T-cell cross-reactivity with Mycobacterium tuberculosis.
Rapid induction of tumor-specific type 1 T helper cells in metastatic melanoma patients by vaccination with mature, cryopreserved, peptide-loaded monocyte-derived dendritic cells.
Depletion of human NK and CD8 cells prior to in vitro H1N1 flu vaccine stimulation increases the number of gamma interferon-secreting cells compared to the initial undepleted population in an ELISPOT assay.
Identification of Kaposi's sarcoma-associated herpesvirus (KSHV)-specific cytotoxic T-lymphocyte epitopes and evaluation of reconstitution of KSHV-specific responses in human immunodeficiency virus type 1-Infected patients receiving highly active antiretroviral therapy.
Magnitude of functional CD8+ T-cell responses to the gag protein of human immunodeficiency virus type 1 correlates inversely with viral load in plasma.
Naturally exposed populations differ in their T1 and T2 responses to the circumsporozoite protein of Plasmodium falciparum.
Induction of T helper type 1 and 2 responses to 19-kilodalton merozoite surface protein 1 in vaccinated healthy volunteers and adults naturally exposed to malaria.
T cell responses to vaccines in infants: defective IFNgamma production after oral polio vaccination.
Expansion of pre-existing, lymph node-localized CD8+ T cells during supervised treatment interruptions in chronic HIV-1 infection.
Detection of CD4(+)- and CD8(+)-T-cell responses to human papillomavirus type 1 antigens expressed at various stages of the virus life cycle by using an enzyme-linked immunospot assay of gamma interferon release.
Human tumor-derived genomic DNA transduced into a recipient cell induces tumor-specific immune responses ex vivo.
The magnitude and specificity of influenza A virus-specific cytotoxic T-lymphocyte responses in humans is related to HLA-A and -B phenotype.
Vaccine-induced immune responses in rodents and nonhuman primates by use of a humanized human immunodeficiency virus type 1 pol gene.
Induction of a T helper cell response against the tumor-associated antigen HER2 using monocyte-derived dendritic cells.
Immune responses to the Mycobacterium tuberculosis-specific antigen ESAT-6 signal subclinical infection among contacts of tuberculosis patients.
Frequencies of ex vivo-activated human immunodeficiency virus type 1-specific gamma-interferon-producing CD8+ T cells in infected children correlate positively with plasma viral load.
HLA-E-dependent presentation of Mtb-derived antigen to human CD8+ T cells.
Human immunodeficiency virus-specific CD8(+) T cells in human breast milk.
Inflammatory cytokines in small intestinal mucosa of patients with potential coeliac disease.
Neonatal dendritic cells are intrinsically biased against Th-1 immune responses.
Quantitative analysis of adenovirus-specific CD4+ T-cell responses from healthy adults.
Differential immunogenicity of Epstein-Barr virus latent-cycle proteins for human CD4(+) T-helper 1 responses.
Association of interleukin-10 cytokine expression status with HLA non-DRB1*02 and Mycobacterium bovis BCG scar-negative status in south Indian pulmonary tuberculosis patients.
Structural features of peptide analogs of human histocompatibility leukocyte antigen class I epitopes that are more potent and immunogenic than wild-type peptide.
Induction of CD4(+) T cell-dependent CD8(+) type 1 responses in humans by a malaria DNA vaccine.
Identification of human immunodeficiency virus type 1 subtype C Gag-, Tat-, Rev-, and Nef-specific elispot-based cytotoxic T-lymphocyte responses for AIDS vaccine design.
Unique T cell effector functions elicited by Plasmodium falciparum epitopes in malaria-exposed Africans tested by three T cell assays.
Characterization of HLA-A3-restricted cytotoxic T lymphocytes reactive against the widely expressed tumor antigen telomerase.
Identification of cyclin B1 as a shared human epithelial tumor-associated antigen recognized by T cells.
Direct ex vivo analysis of antigen-specific IFN-gamma-secreting CD4 T cells in Mycobacterium tuberculosis-infected individuals: associations with clinical disease state and effect of treatment.
Contribution of CD8(+) T cells to gamma interferon production in human tuberculosis.
Induction and abrogation of LACK reactive cells in the evolution of human leishmaniasis.
CD8(+) lymphocytes respond to different HIV epitopes in seronegative and infected subjects.
Mature dendritic cells infected with canarypox virus elicit strong anti-human immunodeficiency virus CD8+ and CD4+ T-cell responses from chronically infected individuals.
Thiols decrease cytokine levels and down-regulate the expression of CD30 on human allergen-specific T helper (Th) 0 and Th2 cells.
Sustained dysfunction of antiviral CD8+ T lymphocytes after infection with hepatitis C virus.
Relative dominance of epitope-specific cytotoxic T-lymphocyte responses in human immunodeficiency virus type 1-infected persons with shared HLA alleles.
Induction of neutralizing antibodies and gag-specific cellular immune responses to an R5 primary isolate of human immunodeficiency virus type 1 in rhesus macaques.
Direct ex vivo measurement of CD8(+) T-lymphocyte responses to human parvovirus B19.
Failure to detect HLA-A*6802-restricted CD8+ T cells specific for Chlamydia trachomatis antigens in subjects from trachoma-endemic communities.
EBNA1-specific CD4+ T cells in healthy carriers of Epstein-Barr virus are primarily Th1 in function.
Antigen-specific inhibition of effector T cell function in humans after injection of immature dendritic cells.
Substantial differences in specificity of HIV-specific cytotoxic T cells in acute and chronic HIV infection.
Cellular immune responses and viral diversity in individuals treated during acute and early HIV-1 infection.
Rapid definition of five novel HLA-A*3002-restricted human immunodeficiency virus-specific cytotoxic T-lymphocyte epitopes by elispot and intracellular cytokine staining assays.
Identification of novel HLA-A2-restricted human immunodeficiency virus type 1-specific cytotoxic T-lymphocyte epitopes predicted by the HLA-A2 supertype peptide-binding motif.
Increased peripheral T cell reactivity to microbial antigens and collagen type II in rheumatoid arthritis after treatment with soluble TNFalpha receptors.
Effect of deworming on human T cell responses to mycobacterial antigens in helminth-exposed individuals before and after bacille Calmette-Guérin (BCG) vaccination.
Role for HLA class II molecules in HIV-1 suppression and cellular immunity following antiretroviral treatment.
Immunization with a HER-2/neu helper peptide vaccine generates HER-2/neu CD8 T-cell immunity in cancer patients.
Late seroconversion in HIV-resistant Nairobi prostitutes despite pre-existing HIV-specific CD8+ responses.
Influence of atopic heredity on IL-4-, IL-12- and IFN-gamma-producing cells in in vitro activated cord blood mononuclear cells.
Treatment of multiple sclerosis with Copaxone (COP): Elispot assay detects COP-induced interleukin-4 and interferon-gamma response in blood cells.
Differential induction of cellular responses by live and dead Leishmania promastigotes in healthy donors.
Specificity of T cells in synovial fluid: high frequencies of CD8(+) T cells that are specific for certain viral epitopes.
Interferon-gamma production in response to in vitro stimulation with collagen type II in rheumatoid arthritis is associated with HLA-DRB1(*)0401 and HLA-DQ8.
Identification of dominant optimal HLA-B60- and HLA-B61-restricted cytotoxic T-lymphocyte (CTL) epitopes: rapid characterization of CTL responses by enzyme-linked immunospot assay.
Cytokine production, serum levels and disease activity in systemic lupus erythematosus.
Strategy for monitoring T cell responses to NY-ESO-1 in patients with any HLA class I allele.
A significant number of human immunodeficiency virus epitope-specific cytotoxic T lymphocytes detected by tetramer binding do not produce gamma interferon.
HLA class I-restricted cytotoxic T-cell epitopes of the respiratory syncytial virus fusion protein.
Anti-human immunodeficiency virus type 1 (HIV-1) CD8(+) T-lymphocyte reactivity during combination antiretroviral therapy in HIV-1-infected patients with advanced immunodeficiency.
Human CD4(+) T lymphocytes consistently respond to the latent Epstein-Barr virus nuclear antigen EBNA1.
CD8(+) T-cell gamma interferon production specific for human immunodeficiency virus type 1 (HIV-1) in HIV-1-infected subjects.
Differential narrow focusing of immunodominant human immunodeficiency virus gag-specific cytotoxic T-lymphocyte responses in infected African and caucasoid adults and children.
HLA-B57-restricted cytotoxic T-lymphocyte activity in a single infected subject toward two optimal epitopes, one of which is entirely contained within the other.
Enhanced binding of antibodies to neutralization epitopes following thermal and chemical inactivation of human immunodeficiency virus type 1.
Diversion of intestinal flow decreases the numbers of interleukin 4 secreting and interferon gamma secreting T lymphocytes in small bowel mucosa.
Consequences of cell death: exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells.
Cross-priming of naive CD8 T cells against melanoma antigens using dendritic cells loaded with killed allogeneic melanoma cells.
Functionally inert HIV-specific cytotoxic T lymphocytes do not play a major role in chronically infected adults and children.
Characterization of a novel respiratory syncytial virus-specific human cytotoxic T-lymphocyte epitope.
Down-regulation of the T cell receptor CD3 zeta chain in rheumatoid arthritis (RA) and its influence on T cell responsiveness.
Multiple sclerosis is associated with an imbalance between tumour necrosis factor-alpha (TNF-alpha)- and IL-10-secreting blood cells that is corrected by interferon-beta (IFN-beta) treatment.
Monitoring CD8 T cell responses to NY-ESO-1: correlation of humoral and cellular immune responses.
Genetic control of schistosome infections by the SM1 locus of the 5q31-q33 region is linked to differentiation of type 2 helper T lymphocytes.
Is an epitope on keratin 17 a major target for autoreactive T lymphocytes in psoriasis?
Natural killer cells in cross-regulation of IL-12 by IL-10 in Leishmania antigen-stimulated blood donor cells.
High frequencies of naive Melan-A/MART-1-specific CD8(+) T cells in a large proportion of human histocompatibility leukocyte antigen (HLA)-A2 individuals.
Induction of HIV-1-specific T cell responses by administration of cytokines in late-stage patients receiving highly active anti-retroviral therapy.
Identification of naturally processed and HLA-presented Epstein-Barr virus peptides recognized by CD4(+) or CD8(+) T lymphocytes from human blood.
T-cell recognition of Mycobacterium tuberculosis culture filtrate fractions in tuberculosis patients and their household contacts.
Control of Leishmania infantum infection is associated with CD8(+) and gamma interferon- and interleukin-5-producing CD4(+) antigen-specific T cells.
Differential T-cell recognition of native and recombinant Mycobacterium tuberculosis GroES.
Increased levels of circulating acetylcholine receptor (AChR)-reactive IL-10-secreting cells are characteristic for myasthenia gravis (MG).
Weak anti-HIV CD8(+) T-cell effector activity in HIV primary infection.
A new cell enzyme-linked immunosorbent assay demonstrates gamma interferon suppression by beta interferon in multiple sclerosis.
Lysophosphatidylcholine (LPC) induces proinflammatory cytokines by a platelet-activating factor (PAF) receptor-dependent mechanism.
Cytokine-producing cells in peripheral blood of children with coeliac disease secrete cytokines with a type 1 profile.
A recombinant vaccinia virus based ELISPOT assay detects high frequencies of Pol-specific CD8 T cells in HIV-1-positive individuals.
Asymptomatic Borrelia-seropositive individuals display the same incidence of Borrelia-specific interferon-gamma (IFN-gamma)-secreting cells in blood as patients with clinical Borrelia infection.
Levels of gamma interferon and interleukin-4 are inversely related to the levels of their corresponding autoantibodies in patients with lower respiratory tract infection.
Proviral load and immune function in blood and lymph node during HIV-1 and HIV-2 infection.
Interleukin-10 responses to liver-stage antigen 1 predict human resistance to Plasmodium falciparum.
Rapid generation of broad T-cell immunity in humans after a single injection of mature dendritic cells.
Strong human immunodeficiency virus (HIV)-specific cytotoxic T-lymphocyte activity in Sydney Blood Bank Cohort patients infected with nef-defective HIV type 1.
Dendritic cells transduced with an adenovirus vector encoding Epstein-Barr virus latent membrane protein 2B: a new modality for vaccination.
Vaccination with mage-3A1 peptide-pulsed mature, monocyte-derived dendritic cells expands specific cytotoxic T cells and induces regression of some metastases in advanced stage IV melanoma.
T cell proliferation, MHC class II restriction and cytokine products of gliadin-stimulated peripheral blood mononuclear cells (PBMC).
Antigen-specific B and T cells in human/mouse radiation chimera following immunization in vivo.
Recovery from Guillain-Barré syndrome is associated with increased levels of neutralizing autoantibodies to interferon-gamma.
Peptide-specific T cell response to Mycobacterium tuberculosis: clinical spectrum, compartmentalization, and effect of chemotherapy.
Cytotoxic T cell responses to multiple conserved HIV epitopes in HIV-resistant prostitutes in Nairobi.
Spontaneous secretion of interferon gamma and interleukin 4 by human intraepithelial and lamina propria gut lymphocytes.
Increased numbers of circulating interferon-gamma- and interleukin-4-secreting cells during normal pregnancy.
Human cytolytic and interferon gamma-secreting CD8+ T lymphocytes specific for Mycobacterium tuberculosis.
38 000 MW antigen-specific major histocompatibility complex class I restricted interferon-gamma-secreting CD8+ T cells in healthy contacts of tuberculosis.
Local cytokine response in Helicobacter pylori-infected subjects.
Differential regulation of Th1 and Th2 cells by p91-110 and p21-40 peptides of the 16-kD alpha-crystallin antigen of Mycobacterium tuberculosis.
Linomide (roquinimex) affects the balance between pro- and anti-inflammatory cytokines in vitro in multiple sclerosis.
Rapid effector function in CD8+ memory T cells.
Analysis of TH1 and TH2 cytokine production in low grade B cell gastric MALT-type lymphomas stimulated in vitro with Helicobacter pylori.
Evaluation of the recombinant 38-kilodalton antigen of Mycobacterium tuberculosis as a potential immunodiagnostic reagent.
Peripheral blood in Sjögren's syndrome does not contain increased levels of T lymphocytes reactive with the recombinant Ro/SS-A 52 kD and La/SS-B 48 kD autoantigens.
T cell responses to a mixture of Mycobacterium tuberculosis peptides with complementary HLA-DR binding profiles.
Local entrapment of interferon gamma in the recovery from Shigella dysenteriae type 1 infection.
Effects of in vitro hyperthermia on proliferative responses and lymphocyte activity.
The outer surface proteins of Lyme disease borrelia spirochetes stimulate T cells to secrete interferon-gamma (IFN-gamma): diagnostic and pathogenic implications.
Interferon gamma and interleukin 4 secreting cells in the gastric antrum in Helicobacter pylori positive and negative gastritis.
Th1/Th2 profiles in tuberculosis, based on the proliferation and cytokine response of blood lymphocytes to mycobacterial antigens.
Number of interleukin-4- and interferon-gamma-secreting human T cells reactive with tetanus toxoid and the mycobacterial antigen PPD or phytohemagglutinin: distinct response profiles depending on the type of antigen used for activation.
Reverse ELISPOT assay for clonal analysis of cytokine production. I. Enumeration of gamma-interferon-secreting cells.
Genetic heterogeneity in Duchenne muscular dystrophy.
Malathion A and B esterases of mouse liver-I.
Bettelli F, Vallerini D, Lagreca I, Barozzi P, Riva G, Nasillo V, Paolini A, D'Amico R, Forghieri F, Morselli M, Pioli V, Gilioli A, Giusti D, Messerotti A, Bresciani P, Cuoghi A, Colaci E, Marasca R, Pagano L, Candoni A, Maertens J, Viale P, Mussini C, Manfredini R, Tagliafico E, Sarti M, Trenti T, Lewis R, Comoli P, Eccher A, Luppi M, Potenza L
PloS one 2024;19(7):e0306728
PloS one 2024;19(7):e0306728
Improved ELISPOT protocol for monitoring Th1/Th17 T-cell response following T.gondii infection.
Fasquelle F, Vreulx AC, Betbeder D
PloS one 2024;19(5):e0301687
PloS one 2024;19(5):e0301687
Multiparameter immunoprofiling for the diagnosis and differentiation of progressive versus nonprogressive nontuberculous mycobacterial lung disease-A pilot study.
Marty PK, Pathakumari B, Cox TM, Van Keulen VP, Erskine CL, Shah M, Vadiyala M, Arias-Sanchez P, Karnakoti S, Pennington KM, Theel ES, Lindestam Arlehamn CS, Peikert T, Escalante P
PloS one 2024;19(4):e0301659
PloS one 2024;19(4):e0301659
Distinct T cell responsiveness to different COVID-19 vaccines and cross-reactivity to SARS-CoV-2 variants with age and CMV status.
Brummelman J, Suárez-Hernández S, de Rond L, Bogaard-van Maurik M, Molenaar P, van Wijlen E, Oomen D, Beckers L, Rots NY, van Beek J, Nicolaie MA, van Els CACM, Boer MC, Kaaijk P, Buisman AM, de Wit J
Frontiers in immunology 2024;15:1392477
Frontiers in immunology 2024;15:1392477
Keratinocyte-derived small extracellular vesicles supply antigens for CD1a-resticted T cells and promote their type 2 bias in the context of filaggrin insufficiency.
Kobiela A, Hewelt-Belka W, Frąckowiak JE, Kordulewska N, Hovhannisyan L, Bogucka A, Etherington R, Piróg A, Dapic I, Gabrielsson S, Brown SJ, Ogg GS, Gutowska-Owsiak D
Frontiers in immunology 2024;15:1369238
Frontiers in immunology 2024;15:1369238
Assessing the immunogenicity risk of salmon calcitonin peptide impurities using in silico and in vitro methods.
Roberts BJ, Mattei AE, Howard KE, Weaver JL, Liu H, Lelias S, Martin WD, Verthelyi D, Pang E, Edwards KJ, De Groot AS
Frontiers in pharmacology 2024;15:1363139
Frontiers in pharmacology 2024;15:1363139
Immune cell phenotype and function patterns across the life course in individuals from rural Uganda.
Nalwoga A, Nakibuule M, Roshan R, Kwizera Mbonye M, Miley W, Whitby D, Newton R, Rochford R, Cose S
Frontiers in immunology 2024;15:1356635
Frontiers in immunology 2024;15:1356635
High frequencies of alpha common cold coronavirus/SARS-CoV-2 cross-reactive functional CD4(+) and CD8(+) memory T cells are associated with protection from symptomatic and fatal SARS-CoV-2 infections in unvaccinated COVID-19 patients.
Coulon PG, Prakash S, Dhanushkodi NR, Srivastava R, Zayou L, Tifrea DF, Edwards RA, Figueroa CJ, Schubl SD, Hsieh L, Nesburn AB, Kuppermann BD, Bahraoui E, Vahed H, Gil D, Jones TM, Ulmer JB, BenMohamed L
Frontiers in immunology 2024;15:1343716
Frontiers in immunology 2024;15:1343716
A novel approach to designing viral precision vaccines applied to SARS-CoV-2.
Trabelsi K, Ben Khalaf N, Ramadan AR, Elsharkawy A, Ashoor D, Chlif S, Boussoffara T, Ben-Ahmed M, Kumar M, Fathallah MD
Frontiers in cellular and infection microbiology 2024;14:1346349
Frontiers in cellular and infection microbiology 2024;14:1346349
Selective lysis of acute myeloid leukemia cells by CD34/CD3 bispecific antibody through the activation of γδ T-cells.
Al Agrafi F, Gaballa A, Hahn P, Arruda LCM, Jaramillo AC, Witsen M, Lehmann S, Önfelt B, Uhlin M, Stikvoort A
Oncoimmunology 2024;13(1):2379063
Oncoimmunology 2024;13(1):2379063
Arginase-1 specific CD8+ T cells react toward malignant and regulatory myeloid cells.
Glöckner HJ, Martinenaite E, Landkildehus Lisle T, Grauslund J, Ahmad S, Met Ö, Thor Straten P, Hald Andersen M
Oncoimmunology 2024;13(1):2318053
Oncoimmunology 2024;13(1):2318053
CD70 identifies alloreactive T cells and represents a potential target for prevention and treatment of acute GVHD.
Verma K, Croft W, Margielewska-Davies S, Pearce H, Stephens C, Diaconescu D, Bevington S, Craddock C, Amel-Kashipaz R, Zuo J, Kinsella FAM, Moss P
Blood advances 2024 Sep 24;8(18):4900-4912
Blood advances 2024 Sep 24;8(18):4900-4912
Safety and Immunogenicity of a Messenger RNA-Based Cytomegalovirus Vaccine in Healthy Adults: Results From a Phase 1 Randomized Clinical Trial.
Fierro C, Brune D, Shaw M, Schwartz H, Knightly C, Lin J, Carfi A, Natenshon A, Kalidindi S, Reuter C, Miller J, Panther L
The Journal of infectious diseases 2024 Sep 23;230(3):e668-e678
The Journal of infectious diseases 2024 Sep 23;230(3):e668-e678
Interferon-γ Responses to Chlamydia trachomatis Vaccine Candidate Proteins in Women With Different Chlamydia Outcomes.
Dziadula J, Sabbaj S, Gupta K, Cutter G, Yu H, Brunham RC, Geisler WM
The Journal of infectious diseases 2024 Sep 23;230(3):569-577
The Journal of infectious diseases 2024 Sep 23;230(3):569-577
An in vitro CD8 T-cell priming assay enables epitope selection for hepatitis C virus vaccines.
Koutsoumpli G, Stasiukonyte N, Hoogeboom BN, Daemen T
Vaccine 2024 Sep 17;42(22):126032
Vaccine 2024 Sep 17;42(22):126032
Detection of virus-specific T cells via ELISpot corroborates early diagnosis in human Borna disease virus 1 (BoDV-1) encephalitis.
Bauswein M, Eid E, Eidenschink L, Schmidt B, Gessner A, Tappe D, Cadar D, Böhmer MM, Jockel L, van Wickeren N, Garibashvili T, Wiesinger I, Wendl C, Heckmann JG, Angstwurm K, Freyer M
Infection 2024 Oct;52(5):1663-1670
Infection 2024 Oct;52(5):1663-1670
Photothermal Prussian blue nanoparticles generate potent multi-targeted tumor-specific T cells as an adoptive cell therapy.
Sweeney EE, Sekhri P, Muniraj N, Chen J, Feng S, Terao J, Chin SJ, Schmidt DE, Bollard CM, Cruz CRY, Fernandes R
Bioengineering & translational medicine 2024 May;9(3):e10639
Bioengineering & translational medicine 2024 May;9(3):e10639
Adaptive immune responses are larger and functionally preserved in a hypervaccinated individual.
Kocher K, Moosmann C, Drost F, Schülein C, Irrgang P, Steininger P, Zhong J, Träger J, Spriewald B, Bock C, Busch DH, Bogdan C, Schubert B, Winkler TH, Tenbusch M, Schuster EM, Schober K
The Lancet. Infectious diseases 2024 May;24(5):e272-e274
The Lancet. Infectious diseases 2024 May;24(5):e272-e274
Neoantigen-specific stimulation of tumor-infiltrating lymphocytes enables effective TCR isolation and expansion while preserving stem-like memory phenotypes.
Levin N, Kim SP, Marquardt CA, Vale NR, Yu Z, Sindiri S, Gartner JJ, Parkhurst M, Krishna S, Lowery FJ, Zacharakis N, Levy L, Prickett TD, Benzine T, Ray S, Masi RV, Gasmi B, Li Y, Islam R, Bera A, Goff SL, Robbins PF, Rosenberg SA
Journal for immunotherapy of cancer 2024 May 30;12(5)
Journal for immunotherapy of cancer 2024 May 30;12(5)
Evaluation of naturally acquired immune responses against novel pre-erythrocytic Plasmodium vivax proteins in a low endemic malaria population located in the Peruvian Amazon Basin.
Ventocilla JA, Tapia LL, Ponce R, Franco A, Leelawong M, Aguiar JC, Baldeviano GC, Wilder BK
Malaria journal 2024 May 23;23(1):163
Malaria journal 2024 May 23;23(1):163
IL-10-producing regulatory cells impact on celiac disease evolution.
Passerini L, Amodio G, Bassi V, Vitale S, Mottola I, Di Stefano M, Fanti L, Sgaramella P, Ziparo C, Furio S, Auricchio R, Barera G, Di Nardo G, Troncone R, Gianfrani C, Gregori S
Clinical immunology (Orlando, Fla.) 2024 Mar;260:109923
Clinical immunology (Orlando, Fla.) 2024 Mar;260:109923
Humoral and T-cell response to SARS-CoV-2 mRNA vaccine in multiple sclerosis patients: Correlations with DMTs and clinical variables.
Barone S, Palmieri C, Gallelli L, Rania V, Pascarella A, Abatino A, Bruno PA, Casarella A, Pasquale M, Manzo L, De Sarro G, Gambardella A, Valentino P
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2024 Mar;21(2):e00307
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2024 Mar;21(2):e00307
Boosting Vaccine Response in Autoimmune Rheumatic Disease Patients With Inadequate Seroconversion: An Analysis of the Immunogenicity of Vector-Based and Inactivated Vaccines.
Vijayan A, Sukumaran A, Jones S, Paul A, Ahmed S, Mehta P, Mohanan M, Kumar S, Easwaran S, Shenoy P
Cureus 2024 Mar;16(3):e55764
Cureus 2024 Mar;16(3):e55764
Secretion of IFN-γ by specific T cells in HCMV infection.
Liang H, Gong S, Gui G, Wang H, Jiang L, Li X, Fan J
Heliyon 2024 Mar 30;10(6):e28177
Heliyon 2024 Mar 30;10(6):e28177
Microfluidic Synthesis of Scalable Layer-by-Layer Multiple Antigen Nano-Delivery Platform for SARS-CoV-2 Vaccines.
Xu Y, Masuda K, Groso C, Hassan R, Zhou Z, Broderick K, Tsuji M, Tison C
Vaccines 2024 Mar 21;12(3)
Vaccines 2024 Mar 21;12(3)
Bivalent mRNA COVID vaccines elicit predominantly cross-reactive CD4(+) T cell clonotypes.
Sop J, Traut CC, Dykema AG, Hunt JH, Beckey TP, Basseth CR, Antar AAR, Laeyendecker O, Smith KN, Blankson JN
Cell reports. Medicine 2024 Mar 19;5(3):101442
Cell reports. Medicine 2024 Mar 19;5(3):101442
Neutralizing antibody titers against D8 genotype and persistence of measles humoral and cell-mediated immunity eight years after the first dose of measles, mumps, and rubella vaccine in Brazilian children.
Kegele Lignani L, de Vasconcellos Carvalhaes de Oliveira R, Matos Dos Santos E, Antonio Bastos Camacho L, Reis Xavier J, Regina da Silva E Sá G, Mendonça Siqueira M, Marques Vieira da Silva A, Gil Melgaço J, Dos Santos Alves N, de Lourdes de Sousa Maia M, Caetano Prates Melo E
Vaccine 2024 Mar 19;42(8):2065-2071
Vaccine 2024 Mar 19;42(8):2065-2071
Circular RNA as a source of neoantigens for cancer vaccines.
Ren Y, Manoharan T, Liu B, Cheng CZM, En Siew B, Cheong WK, Lee KY, Tan IJ, Lieske B, Tan KK, Chia G
Journal for immunotherapy of cancer 2024 Mar 19;12(3)
Journal for immunotherapy of cancer 2024 Mar 19;12(3)
COVID-19 has no impact on disease activity, progression and cognitive performance in people with multiple sclerosis: a 2-year study.
Montini F, Nozzolillo A, Tedone N, Mistri D, Rancoita PM, Zanetta C, Mandelli A, Furlan R, Moiola L, Martinelli V, Rocca MA, Filippi M, Clinical SanRaf MS Study Group
Journal of neurology, neurosurgery, and psychiatry 2024 Mar 13;95(4):342-347
Journal of neurology, neurosurgery, and psychiatry 2024 Mar 13;95(4):342-347
HLA-class II restricted TCR targeting human papillomavirus type 18 E7 induces solid tumor remission in mice.
Long J, Chen X, He M, Ou S, Zhao Y, Yan Q, Ma M, Chen J, Qin X, Zhou X, Chu J, Han Y
Nature communications 2024 Mar 13;15(1):2271
Nature communications 2024 Mar 13;15(1):2271
pH and ROS Responsiveness of Polymersome Nanovaccines for Antigen and Adjuvant Codelivery: An In Vitro and In Vivo Comparison.
Jäger E, Ilina O, Dölen Y, Valente M, van Dinther EAW, Jäger A, Figdor CG, Verdoes M
Biomacromolecules 2024 Mar 11;25(3):1749-1758
Biomacromolecules 2024 Mar 11;25(3):1749-1758
Vaccination with Adenovirus Type 5 Vector-Based COVID-19 Vaccine as the Primary Series in Adults: A Randomized, Double-Blind, Placebo-Controlled Phase 1/2 Clinical Trial.
Zhu Y, Tang R, Li X, Chen X, Wang X, Wang Y, Wang R, Zhu F, Li J
Vaccines 2024 Mar 11;12(3)
Vaccines 2024 Mar 11;12(3)
Cytotoxicity of fourth-generation anti-Trop2 CAR-T cells against breast cancer.
Somboonpatarakun C, Phanthaphol N, Suwanchiwasiri K, Ramwarungkura B, Yuti P, Poungvarin N, Thuwajit P, Junking M, Yenchitsomanus PT
International immunopharmacology 2024 Mar 10;129:111631
International immunopharmacology 2024 Mar 10;129:111631
Impaired immune responses and prolonged viral replication in lung allograft recipients infected with SARS-CoV-2 in the early phase after transplantation.
Glueck OM, Liang X, Badell I, Wratil PR, Graf A, Krebs S, Blum H, Hellmuth JC, Scherer C, Hollaus A, Spaeth PM, Karakoc B, Fuchs T, Zimmermann J, Kauke T, Moosmann A, Keppler OT, Schneider C, Muenchhoff M
Infection 2024 Jun;52(3):847-855
Infection 2024 Jun;52(3):847-855
MAIT cell-MR1 reactivity is highly conserved across multiple divergent species.
Edmans MD, Connelley TK, Morgan S, Pediongco TJ, Jayaraman S, Juno JA, Meehan BS, Dewar PM, Maze EA, Roos EO, Paudyal B, Mak JYW, Liu L, Fairlie DP, Wang H, Corbett AJ, McCluskey J, Benedictus L, Tchilian E, Klenerman P, Eckle SBG
The Journal of biological chemistry 2024 Jun;300(6):107338
The Journal of biological chemistry 2024 Jun;300(6):107338
Electron transport chain capacity expands yellow fever vaccine immunogenicity.
Mok DZ, Tng DJ, Yee JX, Chew VS, Tham CY, Ooi JS, Tan HC, Zhang SL, Lin LZ, Ng WC, Jeeva LL, Murugayee R, Goh KK, Lim TP, Cui L, Cheung YB, Ong EZ, Chan KR, Ooi EE, Low JG
EMBO molecular medicine 2024 Jun;16(6):1310-1323
EMBO molecular medicine 2024 Jun;16(6):1310-1323
A chimeric haemagglutinin-based universal influenza virus vaccine boosts human cellular immune responses directed towards the conserved haemagglutinin stalk domain and the viral nucleoprotein.
Bliss CM, Nachbagauer R, Mariottini C, Cuevas F, Feser J, Naficy A, Bernstein DI, Guptill J, Walter EB, Berlanda-Scorza F, Innis BL, García-Sastre A, Palese P, Krammer F, Coughlan L
EBioMedicine 2024 Jun;104:105153
EBioMedicine 2024 Jun;104:105153
Identification of an HLA-A*11:01-restricted neoepitope of mutant PIK3CA and its specific T cell receptors for cancer immunotherapy targeting hotspot driver mutations.
Shen M, Chen S, Han X, Hao Y, Wang J, Li L, Chen T, Wang B, Zou L, Zhang T, Zhang W, Han X, Wang W, Yu H, Li K, Liu S, Jin A
Cancer immunology, immunotherapy : CII 2024 Jun 4;73(8):150
Cancer immunology, immunotherapy : CII 2024 Jun 4;73(8):150
Phase I Trial of Viral Vector-Based Personalized Vaccination Elicits Robust Neoantigen-Specific Antitumor T-Cell Responses.
D'Alise AM, Leoni G, Cotugno G, Siani L, Vitale R, Ruzza V, Garzia I, Antonucci L, Micarelli E, Venafra V, Gogov S, Capone A, Runswick S, Martin-Liberal J, Calvo E, Moreno V, Symeonides SN, Scarselli E, Bechter O
Clinical cancer research : an official journal of the American Association for Cancer Research 2024 Jun 3;30(11):2412-2423
Clinical cancer research : an official journal of the American Association for Cancer Research 2024 Jun 3;30(11):2412-2423
Rejection resistant CD30.CAR-modified Epstein-Barr virus-specific T cells as an off-the-shelf platform for CD30(+) lymphoma.
Quach DH, Ganesh HR, Briones YD, Nouraee N, Ma A, Hadidi YF, Sharma S, Rooney CM
Molecular therapy. Oncology 2024 Jun 20;32(2):200814
Molecular therapy. Oncology 2024 Jun 20;32(2):200814
Single-cell landscape of functionally cured chronic hepatitis B patients reveals activation of innate and altered CD4-CTL-driven adaptive immunity.
Narmada BC, Khakpoor A, Shirgaonkar N, Narayanan S, Aw PPK, Singh M, Ong KH, Owino CO, Ng JWT, Yew HC, Binte Mohamed Nasir NS, Au VB, Sng R, Kaliaperumal N, Khine HHTW, di Tocco FC, Masayuki O, Naikar S, Ng HX, Chia SL, Seah CXY, Alnawaz MH, Wai CLY, Tay AYL, Mangat KS, Chew V, Yu W, Connolly JE, Periyasamy G, Plissonnier ML, Levrero M, Lim SG, DasGupta R
Journal of hepatology 2024 Jul;81(1):42-61
Journal of hepatology 2024 Jul;81(1):42-61
Cotargeting EBV lytic as well as latent cycle antigens increases T-cell potency against lymphoma.
Sharma S, Mehta NU, Sauer T, Rollins LA, Dittmer DP, Rooney CM
Blood advances 2024 Jul 9;8(13):3360-3371
Blood advances 2024 Jul 9;8(13):3360-3371
Frequency of SARS-CoV-2 Infections among Healthcare Workers in Germany: 3-Year Follow-Up Study.
Stammkötter C, Thümmler L, Korth J, Marenbach B, Braß P, Horn PA, Lindemann M, Dittmer U, Witzke O, Rohn H, Krawczyk A
Infectious disease reports 2024 Jul 19;16(4):615-627
Infectious disease reports 2024 Jul 19;16(4):615-627
SARS-CoV-2-specific T-cell responses are induced in people living with human immunodeficiency virus after booster vaccination.
Wang X, Li Y, Jin J, Chai X, Ma Z, Duan J, Zhang G, Huang T, Zhang X, Zhang T, Wu H, Cao Y, Su B
Chinese medical journal 2024 Jul 18;
Chinese medical journal 2024 Jul 18;
Humoral and Cellular Response Induced by Primary Series and Booster Doses of mRNA Coronavirus Disease 2019 Vaccine in Patients with Cardiovascular Disease: A Longitudinal Study.
Ishihara Y, Naruse H, Fujigaki H, Murakami R, Ando T, Sakurai K, Uehara K, Shimomae K, Sakaguchi E, Hattori H, Sarai M, Ishii J, Fujii R, Ito H, Saito K, Izawa H
Vaccines 2024 Jul 17;12(7)
Vaccines 2024 Jul 17;12(7)
Immunogenicity of the Monovalent Omicron XBB.1.5-Adapted BNT162b2 COVID-19 Vaccine in People Living with HIV (PLWH).
Cherneha M, Zydek I, Braß P, Korth J, Jansen S, Esser S, Karsten CB, Meyer F, Kraiselburd I, Dittmer U, Lindemann M, Horn PA, Witzke O, Thümmler L, Krawczyk A
Vaccines 2024 Jul 17;12(7)
Vaccines 2024 Jul 17;12(7)
Immune responses and clinical outcomes after COVID-19 vaccination in patients with liver disease and liver transplant recipients.
Murray SM, Pose E, Wittner M, Londoño MC, Schaub G, Cook J, Dimitriadis S, Meacham G, Irwin S, Lim Z, Duengelhoef P, Sterneck M, Lohse AW, Perez V, Trivedi P, Bhandal K, Mullish BH, Manousou P, Provine NM, Avitabile E, Carroll M, Tipton T, Healy S, Burra P, Klenerman P, Dunachie S, Kronsteiner B, Maciola AK, Pasqual G, Hernandez-Gea V, Garcia-Pagan JC, Lampertico P, Iavarone M, Gines P, Lütgehetmann M, Schulze Zur Wiesch J, Russo FP, Barnes E, Marjot T, OCTAVE Collaborative Group, PITCH study, and the EASL supported COVID-Hep vaccine network
Journal of hepatology 2024 Jan;80(1):109-123
Journal of hepatology 2024 Jan;80(1):109-123
Humoral SARS-CoV-2 Vaccine Responses in Patients With Giant Cell Arteritis and Polymyalgia Rheumatica: Decay After Primary Vaccination and Effects of the Booster.
van Sleen Y, van der Geest KSM, Buisman AM, Sandovici M, van Baarle D, Brouwer E
Arthritis care & research 2024 Jan;76(1):105-110
Arthritis care & research 2024 Jan;76(1):105-110
N(1)-methylpseudouridylation of mRNA causes +1 ribosomal frameshifting.
Mulroney TE, Pöyry T, Yam-Puc JC, Rust M, Harvey RF, Kalmar L, Horner E, Booth L, Ferreira AP, Stoneley M, Sawarkar R, Mentzer AJ, Lilley KS, Smales CM, von der Haar T, Turtle L, Dunachie S, Klenerman P, Thaventhiran JED, Willis AE
Nature 2024 Jan;625(7993):189-194
Nature 2024 Jan;625(7993):189-194
Multiple SARS-CoV-2 immunizations of an unvaccinated population lead to complex immunity. A T cell reactivity study of blood donors in Antananarivo.
Razafimahatratra SL, Andriatefy OH, Mioramalala DJN, Tsatoromila FAM, Randrianarisaona F, Dussart P, Schoenhals M
Journal of infection and public health 2024 Jan;17(1):175-181
Journal of infection and public health 2024 Jan;17(1):175-181
The spike-specific TCRβ repertoire shows distinct features in unvaccinated or vaccinated patients with SARS-CoV-2 infection.
Vecchio E, Rotundo S, Veneziano C, Abatino A, Aversa I, Gallo R, Giordano C, Serapide F, Fusco P, Viglietto G, Cuda G, Costanzo F, Russo A, Trecarichi EM, Torti C, Palmieri C
Journal of translational medicine 2024 Jan 7;22(1):33
Journal of translational medicine 2024 Jan 7;22(1):33
Structural elucidation of novel pro-inflammatory polysaccharides from Daphne mezereum L.
Butt HS, Ulriksen ES, Rise F, Wangensteen H, Duus JØ, Inngjerdingen M, Inngjerdingen KT
Carbohydrate polymers 2024 Jan 15;324:121554
Carbohydrate polymers 2024 Jan 15;324:121554
Orthopoxvirus-Specific T-Cell Responses in Convalescent Mpox Patients.
Traut CC, Jones JL, Sanders RA, Clark LR, Hamill MM, Stavrakis G, Sop J, Beckey TP, Keller SC, Gilliams EA, Cochran WV, Laeyendecker O, Manabe YC, Mostafa HH, Thomas DL, Hansoti B, Gebo KA, Blankson JN
The Journal of infectious diseases 2024 Jan 12;229(1):54-58
The Journal of infectious diseases 2024 Jan 12;229(1):54-58
A Mixture of T-Cell Epitope Peptides Derived from Human Respiratory Syncytial Virus F Protein Conferred Protection in DR1-TCR Tg Mice.
Guo H, Song Y, Li H, Hu H, Shi Y, Jiang J, Guo J, Cao L, Mao N, Zhang Y
Vaccines 2024 Jan 12;12(1)
Vaccines 2024 Jan 12;12(1)
Infliximab aggregates produced in severe and mild elevated temperature stress conditions induce an extended specific CD4 T-cell response.
Nabhan M, Meunier S, Le-Minh V, Robin B, de Bourayne M, Smadja C, Maillère B, Pallardy M, Turbica I
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2024 Jan 1;192:106670
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2024 Jan 1;192:106670
Immunogenicity and reactogenicity of modified vaccinia Ankara pre-exposure vaccination against mpox according to previous smallpox vaccine exposure and HIV infection: prospective cohort study.
Mazzotta V, Lepri AC, Matusali G, Cimini E, Piselli P, Aguglia C, Lanini S, Colavita F, Notari S, Oliva A, Meschi S, Casetti R, Mondillo V, Vergori A, Bettini A, Grassi G, Pinnetti C, Lapa D, Tartaglia E, Gallì P, Mondi A, Montagnari G, Gagliardini R, Nicastri E, Lichtner M, Sarmati L, Tamburrini E, Mastroianni C, Stingone C, Siddu A, Barca A, Fontana C, Agrati C, Girardi E, Vaia F, Maggi F, Antinori A, Mpox Vaccine Lazio Study Group
EClinicalMedicine 2024 Feb;68:102420
EClinicalMedicine 2024 Feb;68:102420
IFN-γ decreases PD-1 in T lymphocytes from convalescent COVID-19 patients via the AKT/GSK3β signaling pathway.
Song M, Liu X, Shen W, Wang Z, Wu J, Jiang J, Liu Y, Xu T, Bian T, Zhang M, Sun W, Huang M, Ji N
Scientific reports 2024 Feb 29;14(1):5038
Scientific reports 2024 Feb 29;14(1):5038
H3K27M neoepitope vaccination in diffuse midline glioma induces B and T cell responses across diverse HLA loci of a recovered patient.
Boschert T, Kromer K, Lerner T, Lindner K, Haltenhof G, Tan CL, Jähne K, Poschke I, Bunse L, Eisele P, Grassl N, Mildenberger I, Sahm K, Platten M, Lindner JM, Green EW
Science advances 2024 Feb 2;10(5):eadi9091
Science advances 2024 Feb 2;10(5):eadi9091
A Broad-Spectrum Multi-Antigen mRNA/LNP-Based Pan-Coronavirus Vaccine Induced Potent Cross-Protective Immunity Against Infection and Disease Caused by Highly Pathogenic and Heavily Spike-Mutated SARS-CoV-2 Variants of Concern in the Syrian Hamster Model.
Prakash S, Dhanushkodi NR, Singer M, Quadiri A, Zayou L, Vahed H, Coulon PG, Ibraim IC, Tafoya C, Hitchcock L, Landucci G, Forthal DN, El Babsiri A, Tifrea DF, Figueroa CJ, Nesburn AB, Kuppermann BD, Gil D, Jones TM, Ulmer JB, BenMohamed L
bioRxiv : the preprint server for biology 2024 Feb 15;
bioRxiv : the preprint server for biology 2024 Feb 15;
Stimulating T cell responses against patient-derived breast cancer cells with neoantigen peptide-loaded peripheral blood mononuclear cells.
Sueangoen N, Grove H, Chuangchot N, Prasopsiri J, Rungrotmongkol T, Sanachai K, Darai N, Thongchot S, Suriyaphol P, Sa-Nguanraksa D, Thuwajit P, Yenchitsomanus PT, Thuwajit C
Cancer immunology, immunotherapy : CII 2024 Feb 13;73(3):43
Cancer immunology, immunotherapy : CII 2024 Feb 13;73(3):43
Effective and targeted latency reversal in CD4(+) T cells from individuals on long term combined antiretroviral therapy initiated during chronic HIV-1 infection.
Ngo MH, Pankrac J, Ho RCY, Ndashimye E, Pawa R, Ceccacci R, Biru T, Olabode AS, Klein K, Li Y, Kovacs C, Assad R, Jacobson JM, Canaday DH, Tomusange S, Jamiru S, Anok A, Kityamuweesi T, Buule P, Galiwango RM, Reynolds SJ, Quinn TC, Redd AD, Prodger JL, Mann JFS, Arts EJ
Emerging microbes & infections 2024 Dec;13(1):2327371
Emerging microbes & infections 2024 Dec;13(1):2327371
Immunogenicity of BNT162b2 as a first booster after a ChAdOx1 primary series in a Thai geriatric population living with frailty.
Niyomnaitham S, Chokephaibulkit K, Pheerapanyawaranun C, Toh ZQ, Licciardi PV, Satayasanskul A, Jansarikit L, Assantachai P
The journal of nutrition, health & aging 2024 Aug;28(8):100315
The journal of nutrition, health & aging 2024 Aug;28(8):100315
Human effector CD8(+) T cells with an activated and exhausted-like phenotype control tumour growth in vivo in a humanized tumour model.
Mietz J, Kaulfuss M, Egli L, Opitz L, Münz C, Chijioke O
EBioMedicine 2024 Aug;106:105240
EBioMedicine 2024 Aug;106:105240
T cell activation markers CD38 and HLA-DR indicative of non-seroconversion in anti-CD20-treated patients with multiple sclerosis following SARS-CoV-2 mRNA vaccination.
Verstegen NJM, Hagen RR, Kreher C, Kuijper LH, Dijssel JVD, Ashhurst T, Kummer LYL, Palomares Cabeza V, Steenhuis M, Duurland MC, Jongh R, Schoot CEV, Konijn VAL, Mul E, Kedzierska K, van Dam KPJ, Stalman EW, Boekel L, Wolbink G, Tas SW, Killestein J, Rispens T, Wieske L, Kuijpers TW, Eftimov F, van Kempen ZLE, van Ham SM, Ten Brinke A, van de Sandt CE, T2B! immunity against SARS-CoV-2 study group
Journal of neurology, neurosurgery, and psychiatry 2024 Aug 16;95(9):855-864
Journal of neurology, neurosurgery, and psychiatry 2024 Aug 16;95(9):855-864
Treponema pallidum Periplasmic and Membrane Proteins Are Recognized by Circulating and Skin CD4+ T Cells.
Reid TB, Godornes C, Campbell VL, Laing KJ, Tantalo LC, Gomez A, Pholsena TN, Lieberman NAP, Krause TM, Cegielski VI, Culver LA, Nguyen N, Tong DQ, Hawley KL, Greninger AL, Giacani L, Cameron CE, Dombrowski JC, Wald A, Koelle DM
The Journal of infectious diseases 2024 Aug 16;230(2):281-292
The Journal of infectious diseases 2024 Aug 16;230(2):281-292
A First-in-Human Phase I Clinical Study with MVX-ONCO-1, a Personalized Active Immunotherapy, in Patients with Advanced Solid Tumors.
Vernet R, Fernandez E, Migliorini D, Ancrenaz V, Charrier E, Belkouch MC, Von Rohr O, Urwyler M, De Vito C, Renaux J, Villard J, Rubin O, Grogg J, Mach N
Cancer research communications 2024 Aug 1;4(8):2089-2100
Cancer research communications 2024 Aug 1;4(8):2089-2100
Immunogenicity and safety of BNT162b2 vaccination in adolescents with systemic lupus erythematosus.
Piyaphanee N, Charuvanij S, Thepveera S, Toh ZQ, Licciardi PV, Pattaragarn A, Wongprompitak P, Boonnak K, Pheerapanyawaranun C, Chokephaibulkit K
Lupus 2024 Apr;33(5):450-461
Lupus 2024 Apr;33(5):450-461
A novel multicolor fluorescent spot assay for the functional assessment of chimeric antigen receptor (CAR) T-cell products.
Atanackovic D, Iraguha T, Omili D, Avila SV, Fan X, Kocoglu M, Gebru E, Baker JM, Dishanthan N, Dietze KA, Oluwafemi A, Hardy NM, Yared JA, Hankey K, Dahiya S, Rapoport AP, Luetkens T
Cytotherapy 2024 Apr;26(4):318-324
Cytotherapy 2024 Apr;26(4):318-324
The influence of neonatal BCG vaccination on in vitro cytokine responses to Plasmodium falciparum.
Messina NL, Wang M, Forbes EK, Freyne B, Hasang WP, Germano S, Bonnici R, Summons F, Gardiner K, Donath S, Gordon R, Rogerson SJ, Curtis N
BMC immunology 2024 Apr 30;25(1):24
BMC immunology 2024 Apr 30;25(1):24
Construction of novel multi-epitope-based diagnostic biomarker HP16118P and its application in the differential diagnosis of Mycobacterium tuberculosis latent infection.
Wang J, Jiang F, Cheng P, Ye Z, Li L, Yang L, Zhuang L, Gong W
Molecular biomedicine 2024 Apr 29;5(1):15
Molecular biomedicine 2024 Apr 29;5(1):15
Loss of NEDD8 in cancer cells causes vulnerability to immune checkpoint blockade in triple-negative breast cancer.
Papakyriacou I, Kutkaite G, Rúbies Bedós M, Nagarajan D, Alford LP, Menden MP, Mao Y
Nature communications 2024 Apr 27;15(1):3581
Nature communications 2024 Apr 27;15(1):3581
Potential Role of Circulating PD-L1(+) Leukocytes as a Predictor of Response to Anti-PD-(L)1 Therapy in NSCLC Patients.
Anguera G, Mulet M, Zamora C, Osuna-Gómez R, Barba A, Sullivan I, Serra-López J, Cantó E, Vidal S, Majem M
Biomedicines 2024 Apr 25;12(5)
Biomedicines 2024 Apr 25;12(5)
Germline homozygosity and allelic imbalance of HLA-I are common in esophagogastric adenocarcinoma and impair the repertoire of immunogenic peptides.
Garcia-Marquez MA, Thelen M, Bauer E, Maas L, Wennhold K, Lehmann J, Keller D, Nikolić M, George J, Zander T, Schröder W, Müller P, Yazbeck AM, Bruns C, Thomas R, Gathof B, Quaas A, Peifer M, Hillmer AM, von Bergwelt-Baildon M, Schlößer HA
Journal for immunotherapy of cancer 2024 Apr 17;12(4)
Journal for immunotherapy of cancer 2024 Apr 17;12(4)
Higher and Sustained Cell-Mediated Immune Responses After 3 Doses of mRNA COVID-19 Vaccine in Patients With Inflammatory Bowel Disease on Anti-Tumor Necrosis Factor Therapy.
Caldera F, Rolak S, Farraye FA, Necela BM, Cogen D, Zona EE, Schell TL, Ramirez OR, Almasry M, Chun K, Hayney MS, Knutson KL
Clinical and translational gastroenterology 2024 Apr 1;15(4):e00688
Clinical and translational gastroenterology 2024 Apr 1;15(4):e00688
The effects of exercise training for eight weeks on immune cell characteristics among breast cancer survivors.
Arana Echarri A, Struszczak L, Beresford M, Campbell JP, Thompson D, Turner JE
Frontiers in sports and active living 2023;5:1163182
Frontiers in sports and active living 2023;5:1163182
T-Helper 22 Cell Type Responses to Nickel in Contact Allergic Subjects Are Associated with T-Helper 1, T-Helper 2, and T-Helper 17 Cell Cytokine Profile Responses and Patch Test Reactivity.
Masjedi K, Bruze M, Ahlborg N
International archives of allergy and immunology 2023;184(8):832-840
International archives of allergy and immunology 2023;184(8):832-840
Spatiotemporal commonality of the TCR repertoire in a T-cell memory murine model and in metastatic human colorectal cancer.
Haraguchi M, Kiyotani K, Tate T, Sakata S, Sagawa R, Takagi S, Nagayama S, Takeuchi K, Takahashi K, Katayama R
Cancer immunology, immunotherapy : CII 2023 Sep;72(9):2971-2989
Cancer immunology, immunotherapy : CII 2023 Sep;72(9):2971-2989
Early evaluation of the safety, reactogenicity, and immune response after a single dose of modified vaccinia Ankara-Bavaria Nordic vaccine against mpox in children: a national outbreak response.
Ladhani SN, Dowell AC, Jones S, Hicks B, Rowe C, Begum J, Wailblinger D, Wright J, Owens S, Pickering A, Shilltoe B, McMaster P, Whittaker E, Zuo J, Powell A, Amirthalingam G, Mandal S, Lopez-Bernal J, Ramsay ME, Kissane N, Bell M, Watson H, Ho D, Hallis B, Otter A, Moss P, Cohen J
The Lancet. Infectious diseases 2023 Sep;23(9):1042-1050
The Lancet. Infectious diseases 2023 Sep;23(9):1042-1050
Electrolyte imbalance causes suppression of NK and T cell effector function in malignant ascites.
Hrvat A, Schmidt M, Wagner B, Zwanziger D, Kimmig R, Volbracht L, Brandau S, Mallmann-Gottschalk N
Journal of experimental & clinical cancer research : CR 2023 Sep 8;42(1):235
Journal of experimental & clinical cancer research : CR 2023 Sep 8;42(1):235
Optimization of Peripheral Blood Mononuclear Cell Processing for Improved Clinical ELISpot Assay Performance.
Li X, He S, Thomas J, Wu B, Yang TY, Swanson M
The AAPS journal 2023 Sep 28;25(6):93
The AAPS journal 2023 Sep 28;25(6):93
Human CD34(+)-derived complete plasmacytoid and conventional dendritic cell vaccine effectively induces antigen-specific CD8(+) T cell and NK cell responses in vitro and in vivo.
van Eck van der Sluijs J, van Ens D, Brummelman J, Heister D, Sareen A, Truijen L, van Ingen Schenau DS, Heemskerk MHM, Griffioen M, Kester MGD, Schaap NPM, Jansen JH, van der Waart AB, Dolstra H, Hobo W
Cellular and molecular life sciences : CMLS 2023 Sep 20;80(10):298
Cellular and molecular life sciences : CMLS 2023 Sep 20;80(10):298
Targeting nucleic acid sensors in tumor cells to reprogram biogenesis and RNA cargo of extracellular vesicles for T cell-mediated cancer immunotherapy.
Heidegger S, Stritzke F, Dahl S, Daßler-Plenker J, Joachim L, Buschmann D, Fan K, Sauer CM, Ludwig N, Winter C, Enssle S, Li S, Perl M, Görgens A, Haas T, Orberg ET, Göttert S, Wölfel C, Engleitner T, Cortés-Ciriano I, Rad R, Herr W, Giebel B, Ruland J, Bassermann F, Coch C, Hartmann G, Poeck H
Cell reports. Medicine 2023 Sep 19;4(9):101171
Cell reports. Medicine 2023 Sep 19;4(9):101171
Immunogenicity and reactogenicity of fractional, heterologous primary COVID-19 vaccination schedules with BNT162b2 boosters in 5-11-year-old Thai children: A multicenter, prospective, double-blind, randomized control trial.
Wittawatmongkol O, Bunjoungmanee P, Kosalaraksa P, Laoprasopwattana K, Boonsathorn S, Chantasrisawad N, Sudjaritruk T, Niyomnaitham S, Senawong S, Srisutthisamphan K, Quan Toh Z, Rungmaitree S, Nanthapisal S, Phanthanawiboon S, Khantee P, Techasaensiri C, Hirankarn N, Pangprasertkul S, Chokephaibulkit K
Vaccine 2023 Sep 15;41(40):5834-5840
Vaccine 2023 Sep 15;41(40):5834-5840
Fully closed cell sorter for immune cell therapy manufacturing.
Matsumoto M, Tashiro S, Ito T, Takahashi K, Hashimoto G, Kajihara J, Miyahara Y, Shiku H, Katsumoto Y
Molecular therapy. Methods & clinical development 2023 Sep 14;30:367-376
Molecular therapy. Methods & clinical development 2023 Sep 14;30:367-376
Using patient-derived tumor organoids from common epithelial cancers to analyze personalized T-cell responses to neoantigens.
Parikh AY, Masi R, Gasmi B, Hanada KI, Parkhurst M, Gartner J, Sindiri S, Prickett T, Robbins P, Zacharakis N, Beshiri M, Kelly K, Rosenberg SA, Yang JC
Cancer immunology, immunotherapy : CII 2023 Oct;72(10):3149-3162
Cancer immunology, immunotherapy : CII 2023 Oct;72(10):3149-3162
A phase 1 trial of adoptive transfer of vaccine-primed autologous circulating T cells in ovarian cancer.
Bobisse S, Bianchi V, Tanyi JL, Sarivalasis A, Missiaglia E, Pétremand R, Benedetti F, Torigian DA, Genolet R, Barras D, Michel A, Mastroyannis SA, Zsiros E, Dangaj Laniti D, Tsourti Z, Stevenson BJ, Iseli C, Levine BL, Speiser DE, Gfeller D, Bassani-Sternberg M, Powell DJ Jr, June CH, Dafni U, Kandalaft LE, Harari A, Coukos G
Nature cancer 2023 Oct;4(10):1410-1417
Nature cancer 2023 Oct;4(10):1410-1417
A H3K27M-targeted vaccine in adults with diffuse midline glioma.
Grassl N, Poschke I, Lindner K, Bunse L, Mildenberger I, Boschert T, Jähne K, Green EW, Hülsmeyer I, Jünger S, Kessler T, Suwala AK, Eisele P, Breckwoldt MO, Vajkoczy P, Grauer OM, Herrlinger U, Tonn JC, Denk M, Sahm F, Bendszus M, von Deimling A, Winkler F, Wick W, Platten M, Sahm K
Nature medicine 2023 Oct;29(10):2586-2592
Nature medicine 2023 Oct;29(10):2586-2592
Safety and efficacy of one and two booster doses of SARS-CoV-2 mRNA vaccines in kidney transplant recipients: A randomized clinical trial.
Drenko P, Kacer M, Kielberger L, Vlas T, Topolcan O, Kucera R, Reischig T
Transplant infectious disease : an official journal of the Transplantation Society 2023 Oct;25(5):e14150
Transplant infectious disease : an official journal of the Transplantation Society 2023 Oct;25(5):e14150
Metabolic interventions improve HBV envelope-specific T-cell responses in patients with chronic hepatitis B.
Fu YL, Zhou SN, Hu W, Li J, Zhou MJ, Li XY, Wang YY, Zhang P, Chen SY, Fan X, Song JW, Jiao YM, Xu R, Zhang JY, Zhen C, Zhou CB, Yuan JH, Shi M, Wang FS, Zhang C
Hepatology international 2023 Oct;17(5):1125-1138
Hepatology international 2023 Oct;17(5):1125-1138
Comparison of media for a human peripheral blood mononuclear cell-based in vitro vaccine evaluation system.
Gong S, Fajar P, De Vries-Idema J, Huckriede A
Clinical and experimental vaccine research 2023 Oct;12(4):328-336
Clinical and experimental vaccine research 2023 Oct;12(4):328-336
CD4+ and CD8+ T cells and antibodies are associated with protection against Delta vaccine breakthrough infection: a nested case-control study within the PITCH study.
Neale I, Ali M, Kronsteiner B, Longet S, Abraham P, Deeks AS, Brown A, Moore SC, Stafford L, Dobson SL, Plowright M, Newman TAH, Wu MY, Crick COVID Immunity Pipeline, Carr EJ, Beale R, Otter AD, Hopkins S, Hall V, Tomic A, Payne RP, Barnes E, Richter A, Duncan CJA, Turtle L, de Silva TI, Carroll M, Lambe T, Klenerman P, Dunachie S, PITCH Consortium
mBio 2023 Oct 31;14(5):e0121223
mBio 2023 Oct 31;14(5):e0121223
B cell phenotype and serum levels of interferons, BAFF, and APRIL in multisystem inflammatory syndrome in children associated with COVID-19 (MIS-C).
Klocperk A, Bloomfield M, Parackova Z, Aillot L, Fremuth J, Sasek L, David J, Fencl F, Skotnicova A, Rejlova K, Magner M, Hrusak O, Sediva A
Molecular and cellular pediatrics 2023 Oct 28;10(1):15
Molecular and cellular pediatrics 2023 Oct 28;10(1):15
DNMT and HDAC inhibition induces immunogenic neoantigens from human endogenous retroviral element-derived transcripts.
Goyal A, Bauer J, Hey J, Papageorgiou DN, Stepanova E, Daskalakis M, Scheid J, Dubbelaar M, Klimovich B, Schwarz D, Märklin M, Roerden M, Lin YY, Ma T, Mücke O, Rammensee HG, Lübbert M, Loayza-Puch F, Krijgsveld J, Walz JS, Plass C
Nature communications 2023 Oct 23;14(1):6731
Nature communications 2023 Oct 23;14(1):6731
NK Receptors Replace CD28 As the Dominant Source of Signal 2 for Cognate Recognition of Cancer Cells by TAA-specific Effector CD8(+) T Cells.
Dong B, Obermajer N, Tsuji T, Matsuzaki J, Bonura C, Withers H, Long M, Chavel C, Olejniczak SH, Minderman H, Edwards RP, Storkus WJ, Romero P, Kalinski P
Research square 2023 Oct 19;
Research square 2023 Oct 19;
A measles virus-based vaccine induces robust chikungunya virus-specific CD4(+) T-cell responses in a phase II clinical trial.
Schmitz KS, Comvalius AD, Nieuwkoop NJ, Geers D, Weiskopf D, Ramsauer K, Sette A, Tschismarov R, de Vries RD, de Swart RL
Vaccine 2023 Oct 13;41(43):6495-6504
Vaccine 2023 Oct 13;41(43):6495-6504
Neoantigen Targetability in Progressive Advanced Melanoma.
van den Bulk J, Verdegaal EME, van der Ploeg M, Visser M, Nunes JB, de Ru AH, Tjokrodirijo RTN, Ijsselsteijn ME, Janssen NI, van der Breggen R, de Bruin L, de Kok P, Janssen GMC, Ruano D, Kapiteijn EHW, van Veelen PA, de Miranda NFCC, van der Burg SH
Clinical cancer research : an official journal of the American Association for Cancer Research 2023 Oct 13;29(20):4278-4288
Clinical cancer research : an official journal of the American Association for Cancer Research 2023 Oct 13;29(20):4278-4288
Lymph node dendritic cells harbor inducible replication-competent HIV despite years of suppressive ART.
Banga R, Procopio FA, Lana E, Gladkov GT, Roseto I, Parsons EM, Lian X, Armani-Tourret M, Bellefroid M, Gao C, Kauzlaric A, Foglierini M, Alfageme-Abello O, Sluka SHM, Munoz O, Mastrangelo A, Fenwick C, Muller Y, Mkindi CG, Daubenberger C, Cavassini M, Trunfio R, Déglise S, Corpataux JM, Delorenzi M, Lichterfeld M, Pantaleo G, Perreau M
Cell host & microbe 2023 Oct 11;31(10):1714-1731.e9
Cell host & microbe 2023 Oct 11;31(10):1714-1731.e9
Post-vaccination SARS-Cov-2 T-cell receptor repertoires in patients with multiple sclerosis and related disorders.
Algu P, Hameed N, DeAngelis T, Stern J, Harel A
Multiple sclerosis and related disorders 2023 Nov;79:104965
Multiple sclerosis and related disorders 2023 Nov;79:104965
Safety and Efficacy of a Third Dose of the BNT162b2 Vaccine in Liver-Transplanted and Healthy Adolescents.
Sintusek P, Buranapraditkun S, Khunsri S, Thongmee T, Vichaiwattana P, Polsawat W, Poovorawan Y
JPGN reports 2023 Nov;4(4):e373
JPGN reports 2023 Nov;4(4):e373
Myeloperoxidase creates a permissive microenvironmental niche for the progression of multiple myeloma.
Williams CMD, Noll JE, Bradey AL, Duggan J, Wilczek VJ, Masavuli MG, Grubor-Bauk B, Panagopoulos RA, Hewett DR, Mrozik KM, Zannettino ACW, Vandyke K, Panagopoulos V
British journal of haematology 2023 Nov;203(4):614-624
British journal of haematology 2023 Nov;203(4):614-624
Autoreactive T cells targeting type II pneumocyte antigens in COVID-19 convalescent patients.
Lichtensteiger C, Koblischke M, Berner F, Jochum AK, Sinnberg T, Balciunaite B, Purde MT, Walter V, Abdou MT, Hofmeister K, Kohler P, Vernazza P, Albrich WC, Kahlert CR, Zoufaly A, Traugott MT, Kern L, Pietsch U, Kleger GR, Filipovic M, Kneilling M, Cozzio A, Pop O, Bomze D, Bergthaler A, Hasan Ali O, Aberle J, Flatz L
Journal of autoimmunity 2023 Nov;140:103118
Journal of autoimmunity 2023 Nov;140:103118
Epitope-dependent effect of long-term cART on maintenance and recovery of HIV-1-specific CD8(+) T cells.
Kuse N, Gatanaga H, Zhang Y, Chikata T, Oka S, Takiguchi M
Journal of virology 2023 Nov 30;97(11):e0102423
Journal of virology 2023 Nov 30;97(11):e0102423
Natural killer cell responses during SARS-CoV-2 infection and vaccination in people living with HIV-1.
Alrubayyi A, Touizer E, Hameiri-Bowen D, Charlton B, Gea-Mallorquí E, Hussain N, da Costa KAS, Ford R, Rees-Spear C, Fox TA, Williams I, Waters L, Barber TJ, Burns F, Kinloch S, Morris E, Rowland-Jones S, McCoy LE, Peppa D
Scientific reports 2023 Nov 3;13(1):18994
Scientific reports 2023 Nov 3;13(1):18994
TIGIT(+) NK cells in combination with specific gut microbiota features predict response to checkpoint inhibitor therapy in melanoma patients.
Tsakmaklis A, Farowski F, Zenner R, Lesker TR, Strowig T, Schlößer H, Lehmann J, von Bergwelt-Baildon M, Mauch C, Schlaak M, Knuever J, Schweinsberg V, Heinzerling LM, Vehreschild MJGT
BMC cancer 2023 Nov 28;23(1):1160
BMC cancer 2023 Nov 28;23(1):1160
Convalescent Adaptive Immunity Is Highly Heterogenous after SARS-CoV-2 Infection.
Pathakumari B, Marty PK, Shah M, Van Keulen VP, Erskine CL, Block MS, Arias-Sanchez P, Escalante P, Peikert T
Journal of clinical medicine 2023 Nov 16;12(22)
Journal of clinical medicine 2023 Nov 16;12(22)
Machine learning methods and harmonized datasets improve immunogenic neoantigen prediction.
Müller M, Huber F, Arnaud M, Kraemer AI, Altimiras ER, Michaux J, Taillandier-Coindard M, Chiffelle J, Murgues B, Gehret T, Auger A, Stevenson BJ, Coukos G, Harari A, Bassani-Sternberg M
Immunity 2023 Nov 14;56(11):2650-2663.e6
Immunity 2023 Nov 14;56(11):2650-2663.e6
Safety and immunogenicity of a modified COVID-19 mRNA vaccine, SW-BIC-213, as a heterologous booster in healthy adults: an open-labeled, two-centered and multi-arm randomised, phase 1 trial.
Gui YZ, Li XN, Li JX, Shen MY, Zhang MW, Cao Y, Xu HR, Li H, Cheng J, Pan L, Yi YL, Liang LY, Yu CY, Liu GY, Yu C, Hu BJ, Zhu FC, Liang F, Shen H, Jia JY, Li HW, Zhou J, Fan J
EBioMedicine 2023 May;91:104586
EBioMedicine 2023 May;91:104586
Altered cellular immune response to vaccination against SARS-CoV-2 in patients suffering from autoimmunity with B-cell depleting therapy.
Hodl I, Sallegger C, Forstner P, Sareban N, Moritz M, Dreo B, Schulz E, Lackner A, Kleinhappl B, Hatzl S, Moazedi-Fürst F, Seifert-Held T, Heschl B, Khalil M, Enzinger C, Greinix H, Stradner MH, Steinmetz I, Schlenke P, Fessler J
Microbes and infection 2023 May;25(4):105103
Microbes and infection 2023 May;25(4):105103
TAP2 Drives HLA-B∗13:01‒Linked Dapsone Hypersensitivity Syndrome Tolerance and Reactivity.
Sun L, Wang Z, Liu T, Zhao Q, Yu G, Sun Y, Xue X, You J, Yue Z, Mi Z, Liu H, Zhang F
The Journal of investigative dermatology 2023 May;143(5):722-730.e1
The Journal of investigative dermatology 2023 May;143(5):722-730.e1
A protective, single-visit TB vaccination regimen by co-administration of a subunit vaccine with BCG.
Dijkman K, Lindenstrøm T, Rosenkrands I, Søe R, Woodworth JS, Lindestam Arlehamn CS, Mortensen R
NPJ vaccines 2023 May 9;8(1):66
NPJ vaccines 2023 May 9;8(1):66
Cytolytic CD8(+) T cells infiltrate germinal centers to limit ongoing HIV replication in spontaneous controller lymph nodes.
Collins DR, Hitschfel J, Urbach JM, Mylvaganam GH, Ly NL, Arshad U, Racenet ZJ, Yanez AG, Diefenbach TJ, Walker BD
Science immunology 2023 May 19;8(83):eade5872
Science immunology 2023 May 19;8(83):eade5872
The role of CD8+ T-cell clones in immune thrombocytopenia.
Malik A, Sayed AA, Han P, Tan MMH, Watt E, Constantinescu-Bercu A, Cocker ATH, Khoder A, Saputil RC, Thorley E, Teklemichael A, Ding Y, Hart ACJ, Zhang H, Mitchell WA, Imami N, Crawley JTB, Salles-Crawley II, Bussel JB, Zehnder JL, Adams S, Zhang BM, Cooper N
Blood 2023 May 18;141(20):2417-2429
Blood 2023 May 18;141(20):2417-2429
Characterization of Duffy Binding Protein II-specific CD4(+)T cell responses in Plasmodium vivax patients.
Thawornpan P, Malee C, Kochayoo P, Wangriatisak K, Leepiyasakulchai C, Ntumngia FB, De SL, Adams JH, Chootong P
Scientific reports 2023 May 12;13(1):7741
Scientific reports 2023 May 12;13(1):7741
Avelumab in Men With Metastatic Castration-Resistant Prostate Cancer, Enriched for Patients Treated Previously With a Therapeutic Cancer Vaccine.
Madan RA, Redman JM, Karzai F, Dahut WL, Cordes L, Fakhrejahani F, Vu T, Sheikh N, Schlom J, Gulley JL
Journal of immunotherapy (Hagerstown, Md. : 1997) 2023 May 1;46(4):145-151
Journal of immunotherapy (Hagerstown, Md. : 1997) 2023 May 1;46(4):145-151
Estimation of Sensitization Status in Renal Transplant Recipients by Assessing Indirect Pathway CD4 + T Cell Response to Donor Cell-pulsed Dendritic Cell.
Kenta I, Toshihide T, Takashi S, Shintaro S, Yuko M, Manabu O, Takahisa H, Norihiko G, Shunji N, Yoshihiko W, Mai O, Satoshi A, Kohei I, Ezzelarab MB, Takaaki K
Transplantation 2023 May 1;107(5):1079-1088
Transplantation 2023 May 1;107(5):1079-1088
Exercise mobilizes diverse antigen specific T-cells and elevates neutralizing antibodies in humans with natural immunity to SARS CoV-2.
Baker FL, Zúñiga TM, Smith KA, Batatinha H, Kulangara TS, Seckeler MD, Burgess SC, Katsanis E, Simpson RJ
Brain, behavior, & immunity - health 2023 Mar;28:100600
Brain, behavior, & immunity - health 2023 Mar;28:100600
Immunological signature in human cases of monkeypox infection in 2022 outbreak: an observational study.
Agrati C, Cossarizza A, Mazzotta V, Grassi G, Casetti R, De Biasi S, Pinnetti C, Gili S, Mondi A, Cristofanelli F, Lo Tartaro D, Notari S, Maffongelli G, Gagliardini R, Gibellini L, Aguglia C, Lanini S, D'Abramo A, Matusali G, Fontana C, Nicastri E, Maggi F, Girardi E, Vaia F, Antinori A
The Lancet. Infectious diseases 2023 Mar;23(3):320-330
The Lancet. Infectious diseases 2023 Mar;23(3):320-330
A whole blood intracellular cytokine assay optimised for field site studies demonstrates polyfunctionality of CD4+ T cells in acute scrub typhus.
Inthawong M, Pinthong N, Thaiprakhong A, Wangrangsimakul T, Sunyakumthorn P, Hill J, Sonthayanon P, Paris DH, Dunachie SJ, Kronsteiner B
PLoS neglected tropical diseases 2023 Mar;17(3):e0010905
PLoS neglected tropical diseases 2023 Mar;17(3):e0010905
Pre-existing TGF-β-specific T-cell immunity in patients with pancreatic cancer predicts survival after checkpoint inhibitors combined with radiotherapy.
Mortensen REJ, Holmström MO, Lisle TL, Hasselby JP, Willemoe GL, Met Ö, Marie Svane I, Johansen J, Nielsen DL, Chen IM, Andersen MH
Journal for immunotherapy of cancer 2023 Mar;11(3)
Journal for immunotherapy of cancer 2023 Mar;11(3)
A systems immunology study comparing innate and adaptive immune responses in adults to COVID-19 mRNA and adenovirus vectored vaccines.
Ryan FJ, Norton TS, McCafferty C, Blake SJ, Stevens NE, James J, Eden GL, Tee YC, Benson SC, Masavuli MG, Yeow AEL, Abayasingam A, Agapiou D, Stevens H, Zecha J, Messina NL, Curtis N, Ignjatovic V, Monagle P, Tran H, McFadyen JD, Bull RA, Grubor-Bauk B, Lynn MA, Botten R, Barry SE, Lynn DJ
Cell reports. Medicine 2023 Mar 21;4(3):100971
Cell reports. Medicine 2023 Mar 21;4(3):100971
Functional SARS-CoV-2 cross-reactive CD4(+) T cells established in early childhood decline with age.
Humbert M, Olofsson A, Wullimann D, Niessl J, Hodcroft EB, Cai C, Gao Y, Sohlberg E, Dyrdak R, Mikaeloff F, Neogi U, Albert J, Malmberg KJ, Lund-Johansen F, Aleman S, Björkhem-Bergman L, Jenmalm MC, Ljunggren HG, Buggert M, Karlsson AC
Proceedings of the National Academy of Sciences of the United States of America 2023 Mar 21;120(12):e2220320120
Proceedings of the National Academy of Sciences of the United States of America 2023 Mar 21;120(12):e2220320120
Th2-skewed T cells correlate with B cell response to α-Gal and tick antigens in α-Gal syndrome.
Apostolovic D, Grundström J, Kiewiet MBG, Perusko M, Hamsten C, Starkhammar M, Paulie S, van Hage M
The Journal of clinical investigation 2023 Mar 15;133(6)
The Journal of clinical investigation 2023 Mar 15;133(6)
Interferon-gamma FlowSpot assay for the measurement of the T-cell response to cytomegalovirus.
Ye Q, Wang J, Chen M, Nie W, Zhang H, Su X, Ling L, Liu X, Liu L, Wang C, Gao Y
Heliyon 2023 Jun;9(6):e16792
Heliyon 2023 Jun;9(6):e16792
Design and generation of mRNAs encoding conserved regions of SARS-CoV-2 ORF1ab for T cell-mediated immune activation.
Nguyen CM, Luong BA, Thi Tran TT, Nguyen HN, Tran LS
Future virology 2023 Jun;18(8):501-516
Future virology 2023 Jun;18(8):501-516
Skin IL-17A and IFN-γ Production Correlate with Disease Severity in Patients with Psoriasis and Streptococcal Infection.
Della Bella C, Corrà A, Mantengoli E, Galano A, Benagiano M, Bonciani D, Mariotti EB, Pratesi S, Quintarelli L, Aimo C, Grassi A, D'Elios S, Volpi W, Verdelli A, Bartoloni A, Rossolini GM, D'Elios MM, Caproni M
The Journal of investigative dermatology 2023 Jun;143(6):925-932
The Journal of investigative dermatology 2023 Jun;143(6):925-932
Navoximod modulates local HSV-1 replication to reshape tumor immune microenvironment for enhanced immunotherapy via an injectable hydrogel.
Zhuang Q, Zhao B, Lin Z, Liang Y, Zhao Q, Wang Y, Liao N, Tu H, Zheng Y, Chen H, Zeng Y, Zhang D, Liu X
Communications biology 2023 Jun 9;6(1):621
Communications biology 2023 Jun 9;6(1):621
GRT-R910: a self-amplifying mRNA SARS-CoV-2 vaccine boosts immunity for ≥6 months in previously-vaccinated older adults.
Palmer CD, Scallan CD, Kraemer Tardif LD, Kachura MA, Rappaport AR, Koralek DO, Uriel A, Gitlin L, Klein J, Davis MJ, Venkatraman H, Hart MG, Jaroslavsky JR, Kounlavouth S, Marrali M, Nganje CN, Bae K, Yan T, Leodones K, Egorova M, Hong SJ, Kuan J, Grappi S, Garbes P, Jooss K, Ustianowski A
Nature communications 2023 Jun 6;14(1):3274
Nature communications 2023 Jun 6;14(1):3274
Neoantigen-specific CD8 T cells with high structural avidity preferentially reside in and eliminate tumors.
Schmidt J, Chiffelle J, Perez MAS, Magnin M, Bobisse S, Arnaud M, Genolet R, Cesbron J, Barras D, Navarro Rodrigo B, Benedetti F, Michel A, Queiroz L, Baumgaertner P, Guillaume P, Hebeisen M, Michielin O, Nguyen-Ngoc T, Huber F, Irving M, Tissot-Renaud S, Stevenson BJ, Rusakiewicz S, Dangaj Laniti D, Bassani-Sternberg M, Rufer N, Gfeller D, Kandalaft LE, Speiser DE, Zoete V, Coukos G, Harari A
Nature communications 2023 Jun 6;14(1):3188
Nature communications 2023 Jun 6;14(1):3188
Evaluation of QuantiFERON SARS-CoV-2 interferon-γ release assay following SARS-CoV-2 infection and vaccination.
Johnson SA, Phillips E, Adele S, Longet S, Malone T, Mason C, Stafford L, Jamsen A, Gardiner S, Deeks A, Neo J, Blurton EJ, White J, Ali M, Kronsteiner B, Wilson JD, Skelly DT, Jeffery K, Conlon CP, Goulder P, Consortium P, Carroll M, Barnes E, Klenerman P, Dunachie SJ
Clinical and experimental immunology 2023 Jun 5;212(3):249-261
Clinical and experimental immunology 2023 Jun 5;212(3):249-261
Immunological imprinting of humoral immunity to SARS-CoV-2 in children.
Dowell AC, Lancaster T, Bruton R, Ireland G, Bentley C, Sylla P, Zuo J, Scott S, Jadir A, Begum J, Roberts T, Stephens C, Ditta S, Shepherdson R, Powell AA, Brent AJ, Brent B, Baawuah F, Okike I, Beckmann J, Ahmad S, Aiano F, Garstang J, Ramsay ME, Azad R, Waiblinger D, Willett B, Wright J, Ladhani SN, Moss P
Nature communications 2023 Jun 29;14(1):3845
Nature communications 2023 Jun 29;14(1):3845
GRAd-COV2 vaccine provides potent and durable humoral and cellular immunity to SARS-CoV-2 in randomized placebo-controlled phase 2 trial.
Capone S, Fusco FM, Milleri S, Borrè S, Carbonara S, Lo Caputo S, Leone S, Gori G, Maggi P, Cascio A, Lichtner M, Cauda R, Dal Zoppo S, Cossu MV, Gori A, Roda S, Confalonieri P, Bonora S, Missale G, Codeluppi M, Mezzaroma I, Capici S, Pontali E, Libanore M, Diani A, Lanini S, Battella S, Contino AM, Piano Mortari E, Genova F, Parente G, Dragonetti R, Colloca S, Visani L, Iannacone C, Carsetti R, Folgori A, Camerini R, COVITAR study group
Cell reports. Medicine 2023 Jun 20;4(6):101084
Cell reports. Medicine 2023 Jun 20;4(6):101084
Immunogenicity and safety of heterologous immunisation with Ad5-nCOV in healthy adults aged 60 years and older primed with an inactivated SARS-CoV-2 vaccine (CoronaVac): a phase 4, randomised, observer-blind, non-inferiority trial.
Jin PF, Guo XL, Gou JB, Hou LH, Song ZZ, Zhu T, Pan HX, Zhu JH, Shi FJ, Du P, Huang HT, Liu JX, Zheng H, Wang X, Chen Y, Wan P, Wu SP, Wang XW, Xu XY, Yan FR, Li JX, Chen W, Zhu FC
The Lancet regional health. Western Pacific 2023 Jun 20;38:100829
The Lancet regional health. Western Pacific 2023 Jun 20;38:100829
Low levels of neutralizing antibodies against XBB Omicron subvariants after BA.5 infection.
Yang J, Hong W, Lei H, He C, Lei W, Zhou Y, Zhao T, Alu A, Ma X, Li J, Yang L, Wang Z, Wang W, Lu G, Shen G, Lu S, Wu G, Shi H, Wei X
Signal transduction and targeted therapy 2023 Jun 19;8(1):252
Signal transduction and targeted therapy 2023 Jun 19;8(1):252
A pilot study of lymphodepletion intensity for peripheral blood mononuclear cell-derived neoantigen-specific CD8 + T cell therapy in patients with advanced solid tumors.
Li D, Chen C, Li J, Yue J, Ding Y, Wang H, Liang Z, Zhang L, Qiu S, Liu G, Gao Y, Huang Y, Li D, Zhang R, Liu W, Wen X, Li B, Zhang X, Zhang X, Xu RH
Nature communications 2023 Jun 10;14(1):3447
Nature communications 2023 Jun 10;14(1):3447
SARS-CoV-2-specific immune responses and clinical outcomes after COVID-19 vaccination in patients with immune-suppressive disease.
Barnes E, Goodyear CS, Willicombe M, Gaskell C, Siebert S, I de Silva T, Murray SM, Rea D, Snowden JA, Carroll M, Pirrie S, Bowden SJ, Dunachie SJ, Richter A, Lim Z, Satsangi J, Cook G, Pope A, Hughes A, Harrison M, Lim SH, Miller P, Klenerman P, PITCH consortium, Basu N, Gilmour A, Irwin S, Meacham G, Marjot T, Dimitriadis S, Kelleher P, Prendecki M, Clarke C, Mortimer P, McIntyre S, Selby R, Meardon N, Nguyen D, Tipton T, Longet S, Laidlaw S, Orchard K, Ireland G, CONSENSUS, Thomas D, Kearns P, Kirkham A, McInnes IB, OCTAVE Collaborative Group
Nature medicine 2023 Jul;29(7):1760-1774
Nature medicine 2023 Jul;29(7):1760-1774
Engineered tumor-specific T cells using immunostimulatory photothermal nanoparticles.
Sweeney EE, Sekhri P, Telaraja D, Chen J, Chin SJ, Chiappinelli KB, Sanchez CE, Bollard CM, Cruz CRY, Fernandes R
Cytotherapy 2023 Jul;25(7):718-727
Cytotherapy 2023 Jul;25(7):718-727
Specific immune response to mRNA vaccines against COVID-19 in patients receiving allogeneic stem cell transplantation for myeloid malignancy was altered by immunosuppressive therapy.
Macková J, Hainz P, Kryštofová J, Roubalová K, Šťastná-Marková M, Vaníková Š, Musil J, Vydra J, Němečková Š
Leukemia research 2023 Jul;130:107314
Leukemia research 2023 Jul;130:107314
Short Carbon Nanotube-Based Delivery of mRNA for HIV-1 Vaccines.
Xu Y, Ferguson T, Masuda K, Siddiqui MA, Smith KP, Vest O, Brooks B, Zhou Z, Obliosca J, Kong XP, Jiang X, Yamashita M, Moriya T, Tison C
Biomolecules 2023 Jul 7;13(7)
Biomolecules 2023 Jul 7;13(7)
Immunity of Heterologously and Homologously Boosted or Convalescent Individuals Against Omicron BA.1, BA.2, and BA.4/5 Variants.
Jäger M, Diem G, Sahanic S, Fux V, Griesmacher A, Lass-Flörl C, Wilflingseder D, Tancevski I, Posch W
The Journal of infectious diseases 2023 Jul 14;228(2):160-168
The Journal of infectious diseases 2023 Jul 14;228(2):160-168
Chronic Obstructive Pulmonary Disease and Cigarette Smoke Lead to Dysregulated Mucosal-associated Invariant T-Cell Activation.
Huber ME, Larson E, Lust TN, Heisler CM, Harriff MJ
American journal of respiratory cell and molecular biology 2023 Jan;68(1):90-102
American journal of respiratory cell and molecular biology 2023 Jan;68(1):90-102
γδ T cells are effectors of immunotherapy in cancers with HLA class I defects.
de Vries NL, van de Haar J, Veninga V, Chalabi M, Ijsselsteijn ME, van der Ploeg M, van den Bulk J, Ruano D, van den Berg JG, Haanen JB, Zeverijn LJ, Geurts BS, de Wit GF, Battaglia TW, Gelderblom H, Verheul HMW, Schumacher TN, Wessels LFA, Koning F, de Miranda NFCC, Voest EE
Nature 2023 Jan;613(7945):743-750
Nature 2023 Jan;613(7945):743-750
Potent high-avidity neutralizing antibodies and T cell responses after COVID-19 vaccination in individuals with B cell lymphoma and multiple myeloma.
Keppler-Hafkemeyer A, Greil C, Wratil PR, Shoumariyeh K, Stern M, Hafkemeyer A, Ashok D, Hollaus A, Lupoli G, Priller A, Bischof ML, Ihorst G, Engelhardt M, Marks R, Finke J, Bertrand H, Dächert C, Muenchhoff M, Badell I, Emmerich F, Halder H, Spaeth PM, Knolle PA, Protzer U, von Bergwelt-Baildon M, Duyster J, Hartmann TN, Moosmann A, Keppler OT
Nature cancer 2023 Jan;4(1):81-95
Nature cancer 2023 Jan;4(1):81-95
Strong peak immunogenicity but rapid antibody waning following third vaccine dose in older residents of care homes.
Tut G, Lancaster T, Krutikov M, Sylla P, Bone D, Spalkova E, Bentley C, Amin U, Jadir A, Hulme S, Kaur N, Tut E, Bruton R, Wu MY, Harvey R, Carr EJ, Crick COVID Immunity Pipeline, Beale R, Stirrup O, Shrotri M, Azmi B, Fuller C, Baynton V, Irwin-Singer A, Hayward A, Copas A, Shallcross L, Moss P
Nature aging 2023 Jan;3(1):93-104
Nature aging 2023 Jan;3(1):93-104
Beta-lactam hypersensitivity diagnosis in ambulatory and hospitalized settings require different approaches.
Chongpison Y, Palapinyo S, Mongkolpathumrat P, Buranapraditkun S, Thantiworasit P, Klaewsongkram J
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2023 Jan;130(1):84-92.e1
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2023 Jan;130(1):84-92.e1
Seroconversion rates in kidney transplant recipients following SARS-CoV-2 vaccination and its association with immunosuppressive agents: a systematic review and meta-analysis.
Iryaningrum MR, Cahyadi A, Damara FA, Bandiara R, Marbun MBH
Clinical and experimental vaccine research 2023 Jan;12(1):13-24
Clinical and experimental vaccine research 2023 Jan;12(1):13-24
COVID-19 Severity, Cardiological Outcome, and Immunogenicity of mRNA Vaccine on Adult Patients With 22q11.2 DS.
Pulvirenti F, Mortari EP, Putotto C, Terreri S, Fernandez Salinas A, Cinicola BL, Cimini E, Di Napoli G, Sculco E, Milito C, Versacci P, Agrati C, Marino B, Carsetti R, Quinti I
The journal of allergy and clinical immunology. In practice 2023 Jan;11(1):292-305.e2
The journal of allergy and clinical immunology. In practice 2023 Jan;11(1):292-305.e2
Age-related Differences in Immune Reactions to SARS-CoV-2 Spike and Nucleocapsid Antigens.
Morhart P, Kehl S, Schuh W, Hermes K, Meltendorf S, Neubert A, Schneider M, Brunner-Weinzierl M, Schneider H, Lingel H
In vivo (Athens, Greece) 2023 Jan-Feb;37(1):70-78
In vivo (Athens, Greece) 2023 Jan-Feb;37(1):70-78
Activated T cell therapy targeting glioblastoma cancer stem cells.
Miyaguchi K, Wang H, Black KL, Shiao SL, Wang R, Yu JS
Scientific reports 2023 Jan 5;13(1):196
Scientific reports 2023 Jan 5;13(1):196
Tumor cells fail to present MHC-II-restricted epitopes derived from oncogenes to CD4+ T cells.
Brightman SE, Naradikian MS, Thota RR, Becker A, Montero L, Bahmanof M, Premlal ALR, Greenbaum JA, Peters B, Cohen EE, Miller AM, Schoenberger SP
JCI insight 2023 Jan 24;8(2)
JCI insight 2023 Jan 24;8(2)
Attenuated humoral responses in HIV after SARS-CoV-2 vaccination linked to B cell defects and altered immune profiles.
Touizer E, Alrubayyi A, Ford R, Hussain N, Gerber PP, Shum HL, Rees-Spear C, Muir L, Gea-Mallorquí E, Kopycinski J, Jankovic D, Jeffery-Smith A, Pinder CL, Fox TA, Williams I, Mullender C, Maan I, Waters L, Johnson M, Madge S, Youle M, Barber TJ, Burns F, Kinloch S, Rowland-Jones S, Gilson R, Matheson NJ, Morris E, Peppa D, McCoy LE
iScience 2023 Jan 20;26(1):105862
iScience 2023 Jan 20;26(1):105862
A multidisciplinary approach to verify and de-label of drug allergic histories in a university hospital in Thailand: a retrospective descriptive study.
Palapinyo S, Klaewsongkram J, Mongkolpathumrat P, Leelakanok N, Yotsombut K
Journal of pharmaceutical policy and practice 2023 Jan 20;16(1):12
Journal of pharmaceutical policy and practice 2023 Jan 20;16(1):12
Definition and Characterization of SOX11-Derived T Cell Epitopes towards Immunotherapy of Glioma.
Liu Y, Keib A, Neuber B, Wang L, Riemer AB, Bonsack M, Hückelhoven-Krauss A, Schmitt A, Müller-Tidow C, Schmitt M
International journal of molecular sciences 2023 Jan 18;24(3)
International journal of molecular sciences 2023 Jan 18;24(3)
Improved predictions of antigen presentation and TCR recognition with MixMHCpred2.2 and PRIME2.0 reveal potent SARS-CoV-2 CD8(+) T-cell epitopes.
Gfeller D, Schmidt J, Croce G, Guillaume P, Bobisse S, Genolet R, Queiroz L, Cesbron J, Racle J, Harari A
Cell systems 2023 Jan 18;14(1):72-83.e5
Cell systems 2023 Jan 18;14(1):72-83.e5
IFN-γ-Based ELISpot as a New Tool to Detect Human Infections with Borna Disease Virus 1 (BoDV-1): A Pilot Study.
Eidenschink L, Knoll G, Tappe D, Offner R, Drasch T, Ehrl Y, Banas B, Banas MC, Niller HH, Gessner A, Köstler J, Lampl BMJ, Pregler M, Völkl M, Kunkel J, Neumann B, Angstwurm K, Schmidt B, Bauswein M
Viruses 2023 Jan 10;15(1)
Viruses 2023 Jan 10;15(1)
T-cell responses induced by ChAdOx1 nCoV-19 (AZD1222) vaccine to wild-type severe acute respiratory syndrome coronavirus 2 among people with and without HIV in South Africa.
McMahon WC, Kwatra G, Izu A, Koen AL, Greffrath J, Fairlie L, Patel F, Mukendi CK, Mbele NJ, Lala R, Burgers WA, Nunes MC, Cutland CL, Gilbert SC, Lambe T, Pollard AJ, Madhi SA
AIDS (London, England) 2023 Jan 1;37(1):105-112
AIDS (London, England) 2023 Jan 1;37(1):105-112
Preclinical development of a vaccine-based immunotherapy regimen (VBIR) that induces potent and durable T cell responses to tumor-associated self-antigens.
Cho H, Binder J, Weeratna R, Dermyer M, Dai S, Boccia A, Li W, Li S, Jooss K, Merson J, Hollingsworth RE
Cancer immunology, immunotherapy : CII 2023 Feb;72(2):287-300
Cancer immunology, immunotherapy : CII 2023 Feb;72(2):287-300
Long-lasting T-cell response to SARS-CoV-2 antigens after vaccination-a prospective cohort study of HCWs working with COVID-19 patients.
Krifors A, Freyhult E, Rashid Teljebäck M, Wallin RPA, Winqvist O, Månsson E
Infectious diseases (London, England) 2023 Feb;55(2):142-148
Infectious diseases (London, England) 2023 Feb;55(2):142-148
Effective personalized neoantigen vaccine plus anti-PD-1 in a PD-1 blockade-resistant lung cancer patient.
Gao S, Wang J, Zhu Z, Fang J, Zhao Y, Liu Z, Qin H, Wei Y, Xu H, Dan X, Yang L, Xu Q
Immunotherapy 2023 Feb;15(2):57-69
Immunotherapy 2023 Feb;15(2):57-69
SARS-CoV-2-specific T cell and humoral immunity in individuals with and without HIV in an African population: a prospective cohort study.
Ngalamika O, Lidenge SJ, Mukasine MC, Kawimbe M, Kamanzi P, Ngowi JR, Mwaiselage J, Tso FY
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 2023 Feb;127:106-115
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 2023 Feb;127:106-115
CD103 and CD39 coexpression identifies neoantigen-specific cytotoxic T cells in colorectal cancers with low mutation burden.
van den Bulk J, van der Ploeg M, Ijsselsteijn ME, Ruano D, van der Breggen R, Duhen R, Peeters KCMJ, Fariña-Sarasqueta A, Verdegaal EME, van der Burg SH, Duhen T, de Miranda NFCC
Journal for immunotherapy of cancer 2023 Feb;11(2)
Journal for immunotherapy of cancer 2023 Feb;11(2)
Aminobisphosphonates reactivate the latent reservoir in people living with HIV-1.
Sanz M, Weideman AMK, Ward AR, Clohosey ML, Garcia-Recio S, Selitsky SR, Mann BT, Iannone MA, Whitworth CP, Chitrakar A, Garrido C, Kirchherr J, Coffey AR, Tsai YH, Samir S, Xu Y, Copertino D, Bosque A, Jones BR, Parker JS, Hudgens MG, Goonetilleke N, Soriano-Sarabia N
bioRxiv : the preprint server for biology 2023 Feb 7;
bioRxiv : the preprint server for biology 2023 Feb 7;
Identification of T Cell Receptors Targeting a Neoantigen Derived from Recurrently Mutated FGFR3.
Tate T, Matsumoto S, Nemoto K, Leisegang M, Nagayama S, Obama K, Nakamura Y, Kiyotani K
Cancers 2023 Feb 6;15(4)
Cancers 2023 Feb 6;15(4)
Definition of a New HLA B*52-Restricted Rev CTL Epitope Targeted by an HIV-1-Infected Controller.
El Kenz B, Schmidt KG, Ogungbemi-Alt VK, Bergmann S, Steininger P, Korn K, Spriewald B, Harrer EG, Nganou-Makamdop K, Harrer T
Viruses 2023 Feb 18;15(2)
Viruses 2023 Feb 18;15(2)
Cohort-Specific Peptide Reagents Broaden Depth and Breadth Estimates of the CD8 T Cell Response to HIV-1 Gag Potential T Cell Epitopes.
Michelo CM, Fiore-Gartland A, Dalel JA, Hayes P, Tang J, McGowan E, Kilembe W, Fernandez N, Gilmour J, Hunter E
Vaccines 2023 Feb 17;11(2)
Vaccines 2023 Feb 17;11(2)
Serum Neutralization Against SARS-CoV-2 Variants Is Heterogenic and Depends on Vaccination Regimen.
Jäger M, Dichtl S, Bellmann-Weiler R, Reindl M, Lass-Flörl C, Wilflingseder D, Posch W
The Journal of infectious diseases 2023 Feb 14;227(4):528-532
The Journal of infectious diseases 2023 Feb 14;227(4):528-532
Hsp70, in Combination with IL-15 and PD-1 Blocker, Interferes with The Induction of Cytotoxic NK Cells in Relapsed Acute Myeloid Leukemia Patients.
Firouzi J, Hajifathali A, Azimi M, Parvini N, Ghaemi F, Shayan Asl N, Hedayati Asl AA, Safa M, Ebrahimi M
Cell journal 2023 Feb 1;25(2):92-101
Cell journal 2023 Feb 1;25(2):92-101
The Negative Effect of Preexisting Immunity on Influenza Vaccine Responses Transcends the Impact of Vaccine Formulation Type and Vaccination History.
Moritzky SA, Richards KA, Glover MA, Krammer F, Chaves FA, Topham DJ, Branche A, Nayak JL, Sant AJ
The Journal of infectious diseases 2023 Feb 1;227(3):381-390
The Journal of infectious diseases 2023 Feb 1;227(3):381-390
HPV-associated head and neck cancer is characterized by distinct profiles of CD8(+) T cells and myeloid-derived suppressor cells.
Kansy BA, Wehrs TP, Bruderek K, Si Y, Ludwig S, Droege F, Hasskamp P, Henkel U, Dominas N, Hoffmann TK, Horn PA, Schuler M, Gauler TC, Lindemann M, Lang S, Bankfalvi A, Brandau S
Cancer immunology, immunotherapy : CII 2023 Dec;72(12):4367-4383
Cancer immunology, immunotherapy : CII 2023 Dec;72(12):4367-4383
ATOR-1017 (evunzekibart), an Fc-gamma receptor conditional 4-1BB agonist designed for optimal safety and efficacy, activates exhausted T cells in combination with anti-PD-1.
Enell Smith K, Fritzell S, Nilsson A, Barchan K, Rosén A, Schultz L, Varas L, Säll A, Rose N, Håkansson M, von Schantz L, Ellmark P
Cancer immunology, immunotherapy : CII 2023 Dec;72(12):4145-4159
Cancer immunology, immunotherapy : CII 2023 Dec;72(12):4145-4159
Safety, efficacy, and immunogenicity of a replication-defective human cytomegalovirus vaccine, V160, in cytomegalovirus-seronegative women: a double-blind, randomised, placebo-controlled, phase 2b trial.
Das R, Blázquez-Gamero D, Bernstein DI, Gantt S, Bautista O, Beck K, Conlon A, Rosenbloom DIS, Wang D, Ritter M, Arnold B, Annunziato P, Russell KL, V160-002 study group
The Lancet. Infectious diseases 2023 Dec;23(12):1383-1394
The Lancet. Infectious diseases 2023 Dec;23(12):1383-1394
Immunogenicity, safety, and preliminary efficacy evaluation of OVX836, a nucleoprotein-based universal influenza A vaccine candidate: a randomised, double-blind, placebo-controlled, phase 2a trial.
Leroux-Roels I, Willems P, Waerlop G, Janssens Y, Tourneur J, De Boever F, Bruhwyler J, Alhatemi A, Jacobs B, Nicolas F, Leroux-Roels G, Le Vert A
The Lancet. Infectious diseases 2023 Dec;23(12):1360-1369
The Lancet. Infectious diseases 2023 Dec;23(12):1360-1369
TScan-II: A genome-scale platform for the de novo identification of CD4(+) T cell epitopes.
Dezfulian MH, Kula T, Pranzatelli T, Kamitaki N, Meng Q, Khatri B, Perez P, Xu Q, Chang A, Kohlgruber AC, Leng Y, Jupudi AA, Joachims ML, Chiorini JA, Lessard CJ, Farris AD, Muthuswamy SK, Warner BM, Elledge SJ
Cell 2023 Dec 7;186(25):5569-5586.e21
Cell 2023 Dec 7;186(25):5569-5586.e21
Impaired long-term anti-HBs responses in choronic hepatitis C patients: Results from a five-year follow-up study with healthy control.
Yan B, Lu J, Jia L, Feng Y, Wang J, Meng X, Liang X, Wang F, Wan Y, Xu A, Zhang L
Human vaccines & immunotherapeutics 2023 Dec 31;19(1):2168432
Human vaccines & immunotherapeutics 2023 Dec 31;19(1):2168432
Personalized neoantigen-based T cell therapy triggers cytotoxic lymphocytes expressing polyclonal TCR against metastatic ovarian cancer.
Hung SI, Chu MT, Hou MM, Lee YS, Yang CK, Chu SY, Liu FY, Hsu HC, Pao SC, Teng YC, Chen CB, Chao A, Chung WH, Chang JW, Lai CH
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec 31;169:115928
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec 31;169:115928
Investigating the Immune Basis of Green Tea Extract Induced Liver Injury in Healthy Donors Expressing HLA-B*35:01.
Line J, Ali SE, Grice S, Rao T, Naisbitt DJ
Chemical research in toxicology 2023 Dec 18;36(12):1872-1875
Chemical research in toxicology 2023 Dec 18;36(12):1872-1875
HBHA-IGRA and cytotoxic mediators release assays for the diagnosis of cervical tuberculous lymphadenitis.
Bchiri S, Bouzekri A, Ouni R, Lahiani R, Romdhane E, Dekhil N, Ben Hamouda S, Mardassi H, Ferjani A, Petit E, Corbière V, Rammeh S, Mascart F, Locht C, Ben Salah M, Barbouche MR, Benabdessalem C
Microbiology spectrum 2023 Dec 12;11(6):e0163823
Microbiology spectrum 2023 Dec 12;11(6):e0163823
Humoral and T cell responses to SARS-CoV-2 reveal insights into immunity during the early pandemic period in Pakistan.
Masood KI, Qaiser S, Abidi SH, Khan E, Mahmood SF, Hussain A, Ghous Z, Imtiaz K, Ali N, Hasan M, Memon HA, Yameen M, Ali S, Baloch S, Lakhani G, Alves PM, Iqbal NT, Ahmed K, Iqbal J, Bhutta ZA, Hussain R, Rottenberg M, Simas JP, Veldhoen M, Ghias K, Hasan Z
BMC infectious diseases 2023 Dec 1;23(1):846
BMC infectious diseases 2023 Dec 1;23(1):846
Intradermal skin test with mRNA vaccines as a surrogate marker of T cell immunity in immunocompromised patients.
Fallet B, Foglierini M, Porret R, Alcaraz-Serna A, Sauvage C, Jenelten R, Caplanusi T, Gilliet M, Perez L, Fenwick C, Genolet R, Harari A, Bobisse S, Gottardo R, Pantaleo G, Muller YD
The Journal of infection 2023 Aug;87(2):111-119
The Journal of infection 2023 Aug;87(2):111-119
Effect of wash media type during PBMC isolation on downstream characterization of SARS-CoV-2-specific T cells.
Congrave-Wilson Z, Kim M, Sutherland A, Jumarang J, Lee Y, Del Valle J, Cheng WA, da Silva Antunes R, Pannaraj PS
Journal of immunological methods 2023 Aug;519:113520
Journal of immunological methods 2023 Aug;519:113520
Impact of delayed PBMC processing on functional and genomic assays.
Yi PC, Zhuo L, Lin J, Chang C, Goddard A, Yoon OK
Journal of immunological methods 2023 Aug;519:113514
Journal of immunological methods 2023 Aug;519:113514
Lenalidomide overcomes the resistance to third-generation CD19-CAR-T cell therapy in preclinical models of diffuse large B-cell lymphoma.
Jin Z, Xiang R, Qing K, Li D, Liu Z, Li X, Zhu H, Zhang Y, Wang L, Xue K, Liu H, Xu Z, Wang Y, Li J
Cellular oncology (Dordrecht, Netherlands) 2023 Aug;46(4):1143-1157
Cellular oncology (Dordrecht, Netherlands) 2023 Aug;46(4):1143-1157
Validation of Multi-epitope Peptides Encapsulated in PLGA Nanoparticles Against Influenza A Virus.
Heng WT, Lim HX, Tan KO, Poh CL
Pharmaceutical research 2023 Aug;40(8):1999-2025
Pharmaceutical research 2023 Aug;40(8):1999-2025
SARS-CoV-2-specific T cell therapy for severe COVID-19: a randomized phase 1/2 trial.
Papadopoulou A, Karavalakis G, Papadopoulou E, Xochelli A, Bousiou Z, Vogiatzoglou A, Papayanni PG, Georgakopoulou A, Giannaki M, Stavridou F, Vallianou I, Kammenou M, Varsamoudi E, Papadimitriou V, Giannaki C, Sileli M, Stergiouda Z, Stefanou G, Kourlaba G, Gounelas G, Triantafyllidou M, Siotou E, Karaglani A, Zotou E, Chatzika G, Boukla A, Papalexandri A, Koutra MG, Apostolou D, Pitsiou G, Morfesis P, Doumas M, Karampatakis T, Kapravelos N, Bitzani M, Theodorakopoulou M, Serasli E, Georgolopoulos G, Sakellari I, Fylaktou A, Tryfon S, Anagnostopoulos A, Yannaki E
Nature medicine 2023 Aug;29(8):2019-2029
Nature medicine 2023 Aug;29(8):2019-2029
Multifunctional IgG/IgM antibodies and cellular cytotoxicity are elicited by the full-length MSP1 SumayaVac-1 malaria vaccine.
Rosenkranz M, Fürle K, Hibbert J, Ulmer A, Ali A, Giese T, Blank A, Haefeli WE, Böhnlein E, Lanzer M, Thomson-Luque R
NPJ vaccines 2023 Aug 9;8(1):112
NPJ vaccines 2023 Aug 9;8(1):112
Structural definition of HLA class II-presented SARS-CoV-2 epitopes reveals a mechanism to escape pre-existing CD4(+) T cell immunity.
Chen Y, Mason GH, Scourfield DO, Greenshields-Watson A, Haigh TA, Sewell AK, Long HM, Gallimore AM, Rizkallah P, MacLachlan BJ, Godkin A
Cell reports 2023 Aug 29;42(8):112827
Cell reports 2023 Aug 29;42(8):112827
Persistent symptoms after COVID-19 are not associated with differential SARS-CoV-2 antibody or T cell immunity.
Altmann DM, Reynolds CJ, Joy G, Otter AD, Gibbons JM, Pade C, Swadling L, Maini MK, Brooks T, Semper A, McKnight Á, Noursadeghi M, Manisty C, Treibel TA, Moon JC, COVIDsortium investigators, Boyton RJ
Nature communications 2023 Aug 23;14(1):5139
Nature communications 2023 Aug 23;14(1):5139
Omicron infection following vaccination enhances a broad spectrum of immune responses dependent on infection history.
Hornsby H, Nicols AR, Longet S, Liu C, Tomic A, Angyal A, Kronsteiner B, Tyerman JK, Tipton T, Zhang P, Gallis M, Supasa P, Selvaraj M, Abraham P, Neale I, Ali M, Barratt NA, Nell JM, Gustafsson L, Strickland S, Grouneva I, Rostron T, Moore SC, Hering LM, Dobson SL, Bibi S, Mongkolsapaya J, Lambe T, Wootton D, Hall V, Hopkins S, Dong T, Barnes E, Screaton G, PITCH Consortium, Richter A, Turtle L, Rowland-Jones SL, Carroll M, Duncan CJA, Klenerman P, Dunachie SJ, Payne RP, de Silva TI
Nature communications 2023 Aug 21;14(1):5065
Nature communications 2023 Aug 21;14(1):5065
Proteogenomic analysis reveals RNA as a source for tumor-agnostic neoantigen identification.
Tretter C, de Andrade Krätzig N, Pecoraro M, Lange S, Seifert P, von Frankenberg C, Untch J, Zuleger G, Wilhelm M, Zolg DP, Dreyer FS, Bräunlein E, Engleitner T, Uhrig S, Boxberg M, Steiger K, Slotta-Huspenina J, Ochsenreither S, von Bubnoff N, Bauer S, Boerries M, Jost PJ, Schenck K, Dresing I, Bassermann F, Friess H, Reim D, Grützmann K, Pfütze K, Klink B, Schröck E, Haller B, Kuster B, Mann M, Weichert W, Fröhling S, Rad R, Hiltensperger M, Krackhardt AM
Nature communications 2023 Aug 2;14(1):4632
Nature communications 2023 Aug 2;14(1):4632
Phase III Pivotal comparative clinical trial of intranasal (iNCOVACC) and intramuscular COVID 19 vaccine (Covaxin(®)).
Singh C, Verma S, Reddy P, Diamond MS, Curiel DT, Patel C, Jain MK, Redkar SV, Bhate AS, Gundappa V, Konatham R, Toppo L, Joshi AC, Kushwaha JS, Singh AP, Bawankule S, Ella R, Prasad S, Ganneru B, Chiteti SR, Kataram S, Vadrevu KM
NPJ vaccines 2023 Aug 18;8(1):125
NPJ vaccines 2023 Aug 18;8(1):125
Phase 1 clinical trial to assess safety and efficacy of NY-ESO-1-specific TCR T cells in HLA-A∗02:01 patients with advanced soft tissue sarcoma.
Pan Q, Weng D, Liu J, Han Z, Ou Y, Xu B, Peng R, Que Y, Wen X, Yang J, Zhong S, Zeng L, Chen A, Gong H, Lin Y, Chen J, Ma K, Lau JYN, Li Y, Fan Z, Zhang X
Cell reports. Medicine 2023 Aug 15;4(8):101133
Cell reports. Medicine 2023 Aug 15;4(8):101133
Complementarity-determining region clustering may cause CAR-T cell dysfunction.
Sarén T, Saronio G, Marti Torrell P, Zhu X, Thelander J, Andersson Y, Hofström C, Nestor M, Dimberg A, Persson H, Ramachandran M, Yu D, Essand M
Nature communications 2023 Aug 10;14(1):4732
Nature communications 2023 Aug 10;14(1):4732
Higher Cell-Mediated Immune Responses in Patients With Inflammatory Bowel Disease on Anti-TNF Therapy After COVID-19 Vaccination.
Caldera F, Farraye FA, Necela BM, Cogen D, Saha S, Wald A, Daoud ND, Chun K, Grimes I, Lutz M, Van Helden SR, Swift MD, Virk A, Bharucha AE, Patel TC, Gores GJ, Chumsri S, Hayney MS, Knutson KL
Inflammatory bowel diseases 2023 Aug 1;29(8):1202-1209
Inflammatory bowel diseases 2023 Aug 1;29(8):1202-1209
Validation of the performance and suitability of a new class of FBS optimized for use in single-cell functional assays.
Berrong M, Ferrari G, Porth C, Davis D, Denny T, Janetzki S, Rountree W
Journal of immunological methods 2023 Apr;515:113452
Journal of immunological methods 2023 Apr;515:113452
Exhausted intratumoral Vδ2(-) γδ T cells in human kidney cancer retain effector function.
Rancan C, Arias-Badia M, Dogra P, Chen B, Aran D, Yang H, Luong D, Ilano A, Li J, Chang H, Kwek SS, Zhang L, Lanier LL, Meng MV, Farber DL, Fong L
Nature immunology 2023 Apr;24(4):612-624
Nature immunology 2023 Apr;24(4):612-624
Third dose of COVID-19 mRNA vaccine closes the gap in immune response between naïve nursing home residents and healthy adults.
Pannus P, Depickère S, Kemlin D, Georges D, Houben S, Olislagers V, Waegemans A, De Craeye S, Francotte A, Chaumont F, Van Oostveldt C, Heyndrickx L, Michiels J, Willems E, Dhondt E, Krauchuk M, Schmickler MN, Verbrugghe M, Van Loon N, Dierick K, Matagne A, Desombere I, Ariën KK, Marchant A, Goossens ME
Vaccine 2023 Apr 24;41(17):2829-2836
Vaccine 2023 Apr 24;41(17):2829-2836
PP19128R, a Multiepitope Vaccine Designed to Prevent Latent Tuberculosis Infection, Induced Immune Responses In Silico and In Vitro Assays.
Jiang F, Peng C, Cheng P, Wang J, Lian J, Gong W
Vaccines 2023 Apr 17;11(4)
Vaccines 2023 Apr 17;11(4)
Case report: Treatment of long COVID with a SARS-CoV-2 antiviral and IL-6 blockade in a patient with rheumatoid arthritis and SARS-CoV-2 antigen persistence.
Visvabharathy L, Orban ZS, Koralnik IJ
Frontiers in medicine 2022;9:1003103
Frontiers in medicine 2022;9:1003103
Safety and immunogenicity of a reduced dose of the BNT162b2 mRNA COVID-19 vaccine (REDU-VAC): A single blind, randomized, non-inferiority trial.
Pannus P, Depickère S, Kemlin D, Houben S, Neven KY, Heyndrickx L, Michiels J, Willems E, De Craeye S, Francotte A, Chaumont F, Olislagers V, Waegemans A, Verbrugghe M, Schmickler MN, Van Gucht S, Dierick K, Marchant A, Desombere I, Ariën KK, Goossens ME
PLOS global public health 2022;2(12):e0001308
PLOS global public health 2022;2(12):e0001308
A phase 1b open-label dose-finding study of ustekinumab in young adults with type 1 diabetes.
Marwaha AK, Chow S, Pesenacker AM, Cook L, Sun A, Long SA, Yang JHM, Ward-Hartstonge KA, Williams E, Domingo-Vila C, Halani K, Harris KM, Tree TIM, Levings MK, Elliott T, Tan R, Dutz JP
Immunotherapy advances 2022;2(1):ltab022
Immunotherapy advances 2022;2(1):ltab022
Early SARS-CoV-2 dynamics and immune responses in unvaccinated participants of an intensely sampled longitudinal surveillance study.
Gunawardana M, Webster S, Rivera S, Cortez JM Jr, Breslin J, Pinales C, Buser C, Ibarrondo FJ, Yang OO, Bobardt M, Gallay PA, Adler AP, Ramirez CM, Anton PA, Baum MM
Communications medicine 2022;2:129
Communications medicine 2022;2:129
Durable T-cellular and humoral responses in SARS-CoV-2 hospitalized and community patients.
Mohn KG, Bredholt G, Zhou F, Madsen A, Onyango TB, Fjelltveit EB, Jalloh SL, Brokstad KA, Cantoni D, Mayora-Neto M, Temperton N, Langeland N, Cox RJ, Bergen COVID-19 research group
PloS one 2022;17(2):e0261979
PloS one 2022;17(2):e0261979
Harmonization and qualification of an IFN-γ Enzyme-Linked ImmunoSpot assay (ELISPOT) to measure influenza-specific cell-mediated immunity within the FLUCOP consortium.
Waerlop G, Leroux-Roels G, Lambe T, Bellamy D, Medaglini D, Pettini E, Cox RJ, Trieu MC, Davies R, Bredholt G, Montomoli E, Gianchecchi E, Clement F
Frontiers in immunology 2022;13:984642
Frontiers in immunology 2022;13:984642
T cell perturbations persist for at least 6 months following hospitalization for COVID-19.
Govender M, Hopkins FR, Göransson R, Svanberg C, Shankar EM, Hjorth M, Nilsdotter-Augustinsson Å, Sjöwall J, Nyström S, Larsson M
Frontiers in immunology 2022;13:931039
Frontiers in immunology 2022;13:931039
Brief Research Report: Anti-SARS-CoV-2 Immunity in Long Lasting Responders to Cancer Immunotherapy Through mRNA-Based COVID-19 Vaccination.
Sisteré-Oró M, Wortmann DDJ, Andrade N, Aguilar A, Mayo de Las Casas C, Casabal FG, Torres S, Bona Salinas E, Raventos Soler L, Arcas A, Esparre C, Garcia B, Valarezo J, Rosell R, Güerri-Fernandez R, Gonzalez-Cao M, Meyerhans A
Frontiers in immunology 2022;13:908108
Frontiers in immunology 2022;13:908108
CoVITEST: A Fast and Reliable Method to Monitor Anti-SARS-CoV-2 Specific T Cells From Whole Blood.
Egri N, Olivé V, Hernández-Rodríguez J, Castro P, De Guzman C, Heredia L, Segura AC, Fernandez MD, de Moner N, Torradeflot M, Ballús J, Martinez R, Vazquez M, Costa MV, Dobaño C, Mazza M, Mazzotti L, Pascal M, Juan M, González-Navarro EA, Calderón H
Frontiers in immunology 2022;13:848586
Frontiers in immunology 2022;13:848586
Children and Adults With Mild COVID-19: Dynamics of the Memory T Cell Response up to 10 Months.
Kaaijk P, Pimentel VO, Emmelot ME, Poelen MCM, Cevirgel A, Schepp RM, den Hartog G, Reukers DFM, Beckers L, van Beek J, van Els CACM, Meijer A, Rots NY, de Wit J
Frontiers in immunology 2022;13:817876
Frontiers in immunology 2022;13:817876
Evaluation of radio-immunotherapy sequence on immunological responses and clinical outcomes in patients with melanoma brain metastases (ELEKTRA).
Hassel JC, Schank TE, Smetak H, Mühlbauer J, Salzmann M, Machiraju D, Menzer C, Lang K, König L, Haefner MF, Hülsmeyer I, Kohler C, Spang R, Enk A, Debus J, Beckhove P
Oncoimmunology 2022;11(1):2066609
Oncoimmunology 2022;11(1):2066609
Identification of Claudin 6-specific HLA class I- and HLA class II-restricted T cell receptors for cellular immunotherapy in ovarian cancer.
Matsuzaki J, Lele S, Odunsi K, Tsuji T
Oncoimmunology 2022;11(1):2020983
Oncoimmunology 2022;11(1):2020983
Transcriptional and functional analyses of neoantigen-specific CD4 T cells during a profound response to anti-PD-L1 in metastatic Merkel cell carcinoma.
Church C, Pulliam T, Longino N, Park SY, Smythe KS, Makarov V, Riaz N, Jing L, Amezquita R, Campbell JS, Gottardo R, Pierce RH, Choi J, Chan TA, Koelle DM, Nghiem P
Journal for immunotherapy of cancer 2022 Sep;10(9)
Journal for immunotherapy of cancer 2022 Sep;10(9)
Interferon-γ induces immunosuppression in salivary adenoid cystic carcinoma by regulating programmed death ligand 1 secretion.
Fu Q, Liu X, Xia H, Li Y, Yu Z, Liu B, Xiong X, Chen G
International journal of oral science 2022 Sep 28;14(1):47
International journal of oral science 2022 Sep 28;14(1):47
Safety and immune response kinetics of GRAd-COV2 vaccine: phase 1 clinical trial results.
Agrati C, Castilletti C, Battella S, Cimini E, Matusali G, Sommella A, Sacchi A, Colavita F, Contino AM, Bordoni V, Meschi S, Gramigna G, Barra F, Grassi G, Bordi L, Lapa D, Notari S, Casetti R, Bettini A, Francalancia M, Ciufoli F, Vergori A, Vita S, Gentile M, Raggioli A, Plazzi MM, Bacchieri A, Nicastri E, Antinori A, Milleri S, Lanini S, Colloca S, Girardi E, Camerini R, Ippolito G, Vaia F, Folgori A, Capone S
NPJ vaccines 2022 Sep 24;7(1):111
NPJ vaccines 2022 Sep 24;7(1):111
Accumulation of mutations in antibody and CD8 T cell epitopes in a B cell depleted lymphoma patient with chronic SARS-CoV-2 infection.
Khatamzas E, Antwerpen MH, Rehn A, Graf A, Hellmuth JC, Hollaus A, Mohr AW, Gaitzsch E, Weiglein T, Georgi E, Scherer C, Stecher SS, Gruetzner S, Blum H, Krebs S, Reischer A, Leutbecher A, Subklewe M, Dick A, Zange S, Girl P, Müller K, Weigert O, Hopfner KP, Stemmler HJ, von Bergwelt-Baildon M, Keppler OT, Wölfel R, Muenchhoff M, Moosmann A
Nature communications 2022 Sep 23;13(1):5586
Nature communications 2022 Sep 23;13(1):5586
A randomized controlled trial of heterologous ChAdOx1 nCoV-19 and recombinant subunit vaccine MVC-COV1901 against COVID-19.
Chen CJ, Yang LY, Chang WY, Huang YC, Chiu CH, Shih SR, Huang CG, Huang KA
Nature communications 2022 Sep 17;13(1):5466
Nature communications 2022 Sep 17;13(1):5466
Immunodeficiency syndromes differentially impact the functional profile of SARS-CoV-2-specific T cells elicited by mRNA vaccination.
Gao Y, Cai C, Wullimann D, Niessl J, Rivera-Ballesteros O, Chen P, Lange J, Cuapio A, Blennow O, Hansson L, Mielke S, Nowak P, Vesterbacka J, Akber M, Perez-Potti A, Sekine T, Müller TR, Boulouis C, Kammann T, Parrot T, Muvva JR, Sobkowiak M, Healy K, Bogdanovic G, Muschiol S, Söderdahl G, Österborg A, Hellgren F, Grifoni A, Weiskopf D, Sette A, Loré K, Sällberg Chen M, Ljungman P, Sandberg JK, Smith CIE, Bergman P, Ljunggren HG, Aleman S, Buggert M
Immunity 2022 Sep 13;55(9):1732-1746.e5
Immunity 2022 Sep 13;55(9):1732-1746.e5
Effectiveness of Booster Doses of the SARS-CoV-2 Inactivated Vaccine KCONVAC against the Mutant Strains.
Xiao C, Su J, Zhang C, Huang B, Mao L, Ren Z, Bai W, Li H, Lei G, Zheng J, Chen G, Liang X, Qiu C
Viruses 2022 Sep 12;14(9)
Viruses 2022 Sep 12;14(9)
Anti-SARS-CoV-2 T-stem cell memory persists in ocrelizumab-treated MS patients.
Guerrera G, Mandelli A, Finardi A, Orrico M, D'Orso S, Picozza M, Noviello M, Beretta V, Bonetti B, Calabrese M, Marastoni D, De Rossi N, Capra R, Salvetti M, Buscarinu MC, Inglese M, Uccelli A, Moiola L, Raposo C, Muros-Le Rouzic E, Pedotti R, Filippi M, Bonini C, Battistini L, Borsellino G, Furlan R
Multiple sclerosis (Houndmills, Basingstoke, England) 2022 Oct;28(12):1937-1943
Multiple sclerosis (Houndmills, Basingstoke, England) 2022 Oct;28(12):1937-1943
Safety and immunogenicity of VPM1002 versus BCG in South African newborn babies: a randomised, phase 2 non-inferiority double-blind controlled trial.
Cotton MF, Madhi SA, Luabeya AK, Tameris M, Hesseling AC, Shenje J, Schoeman E, Hatherill M, Desai S, Kapse D, Brückner S, Koen A, Jose L, Moultrie A, Bhikha S, Walzl G, Gutschmidt A, Kotze LA, Allies DL, Loxton AG, Shaligram U, Abraham M, Johnstone H, Grode L, Kaufmann SHE, Kulkarni PS
The Lancet. Infectious diseases 2022 Oct;22(10):1472-1483
The Lancet. Infectious diseases 2022 Oct;22(10):1472-1483
De novo construction of T cell compartment in humanized mice engrafted with iPSC-derived thymus organoids.
Zeleniak A, Wiegand C, Liu W, McCormick C, K R, Alavi A, Guan H, Bertera S, Lakomy R, Tajima A, Cohen H, Wong S, Balikani L, Mizerak B, Bar-Joseph Z, Trucco M, Banerjee I, Fan Y
Nature methods 2022 Oct;19(10):1306-1319
Nature methods 2022 Oct;19(10):1306-1319
Arginase-2-specific cytotoxic T cells specifically recognize functional regulatory T cells.
Weis-Banke SE, Lisle TL, Perez-Penco M, Schina A, Hübbe ML, Siersbæk M, Holmström MO, Jørgensen MA, Marie Svane I, Met Ö, Ødum N, Madsen DH, Donia M, Grøntved L, Andersen MH
Journal for immunotherapy of cancer 2022 Oct;10(10)
Journal for immunotherapy of cancer 2022 Oct;10(10)
Administration of broadly neutralizing anti-HIV-1 antibodies at ART initiation maintains long-term CD8(+) T cell immunity.
Rosás-Umbert M, Gunst JD, Pahus MH, Olesen R, Schleimann M, Denton PW, Ramos V, Ward A, Kinloch NN, Copertino DC, Escribà T, Llano A, Brumme ZL, Brad Jones R, Mothe B, Brander C, Fox J, Nussenzweig MC, Fidler S, Caskey M, Tolstrup M, Søgaard OS
Nature communications 2022 Oct 29;13(1):6473
Nature communications 2022 Oct 29;13(1):6473
A phase I study of an adenoviral vector delivering a MUC1/CD40-ligand fusion protein in patients with advanced adenocarcinoma.
Tan TJ, Ang WXG, Wang WW, Chong HS, Tan SH, Cheong R, Chia JW, Syn NL, Shuen WH, Ba R, Kaliaperumal N, Au B, Hopkins R, Li X, Tan AC, Seet AOL, Connolly JE, Arkachaisri T, Chew V, Lajam ABM, Guo D, Chew MZW, Wasser M, Kumar P, Albani S, Toh HC
Nature communications 2022 Oct 28;13(1):6453
Nature communications 2022 Oct 28;13(1):6453
The primordial differentiation of tumor-specific memory CD8(+) T cells as bona fide responders to PD-1/PD-L1 blockade in draining lymph nodes.
Huang Q, Wu X, Wang Z, Chen X, Wang L, Lu Y, Xiong D, Liu Q, Tian Y, Lin H, Guo J, Wen S, Dong W, Yang X, Yuan Y, Yue Z, Lei S, Wu Q, Ran L, Xie L, Wang Y, Gao L, Tian Q, Zhou X, Sun B, Xu L, Tang Z, Ye L
Cell 2022 Oct 27;185(22):4049-4066.e25
Cell 2022 Oct 27;185(22):4049-4066.e25
The oncogenic fusion protein DNAJB1-PRKACA can be specifically targeted by peptide-based immunotherapy in fibrolamellar hepatocellular carcinoma.
Bauer J, Köhler N, Maringer Y, Bucher P, Bilich T, Zwick M, Dicks S, Nelde A, Dubbelaar M, Scheid J, Wacker M, Heitmann JS, Schroeder S, Rieth J, Denk M, Richter M, Klein R, Bonzheim I, Luibrand J, Holzer U, Ebinger M, Brecht IB, Bitzer M, Boerries M, Feucht J, Salih HR, Rammensee HG, Hailfinger S, Walz JS
Nature communications 2022 Oct 27;13(1):6401
Nature communications 2022 Oct 27;13(1):6401
Quiescent innate and adaptive immune responses maintain the long-term integrity of corneal endothelium reconstituted through allogeneic cell injection therapy.
Toda M, Ueno M, Yamada J, Hiraga A, Asada K, Hamuro J, Sotozono C, Kinoshita S
Scientific reports 2022 Oct 27;12(1):18072
Scientific reports 2022 Oct 27;12(1):18072
CD4 T cell epitope abundance in ferritin core potentiates responses to hemagglutinin nanoparticle vaccines.
Nelson SA, Richards KA, Glover MA, Chaves FA, Crank MC, Graham BS, Kanekiyo M, Sant AJ
NPJ vaccines 2022 Oct 26;7(1):124
NPJ vaccines 2022 Oct 26;7(1):124
Evolution of inflammation and immunity in a dengue virus 1 human infection model.
Waickman AT, Lu JQ, Fang H, Waldran MJ, Gebo C, Currier JR, Ware L, Van Wesenbeeck L, Verpoorten N, Lenz O, Tambuyzer L, Herrera-Taracena G, Van Loock M, Endy TP, Thomas SJ
Science translational medicine 2022 Oct 26;14(668):eabo5019
Science translational medicine 2022 Oct 26;14(668):eabo5019
Epstein Barr virus-mediated transformation of B cells from XIAP-deficient patients leads to increased expression of the tumor suppressor CADM1.
Engelmann C, Schuhmachers P, Zdimerova H, Virdi S, Hauri-Hohl M, Pachlopnik Schmid J, Grundhoff A, Marsh RA, Wong WW, Münz C
Cell death & disease 2022 Oct 22;13(10):892
Cell death & disease 2022 Oct 22;13(10):892
Development of an Interferon-Gamma Release Assay (IGRA) to Aid Diagnosis of Histoplasmosis.
Datta K, LaRue R, Permpalung N, Das S, Zhang S, Mehta Steinke S, Bushkin Y, Nosanchuk JD, Marr KA
Journal of clinical microbiology 2022 Oct 19;60(10):e0112822
Journal of clinical microbiology 2022 Oct 19;60(10):e0112822
Immune Response after the Fourth Dose of SARS-CoV-2 mRNA Vaccine Compared to Natural Infection in Three Doses' Vaccinated Solid Organ Transplant Recipients.
Busà R, Russelli G, Miele M, Sorrentino MC, Di Bella M, Timoneri F, Di Mento G, Mularoni A, Vitulo P, Conaldi PG, Bulati M
Viruses 2022 Oct 19;14(10)
Viruses 2022 Oct 19;14(10)
Modification of the HLA-A*24:02 Peptide Binding Pocket Enhances Cognate Peptide-Binding Capacity and Antigen-Specific T Cell Activation.
Murata K, Ly D, Saijo H, Matsunaga Y, Sugata K, Ihara F, Oryoji D, Ohashi Y, Saso K, Wang CH, Zheng EYF, Burt BD, Butler MO, Hirano N
Journal of immunology (Baltimore, Md. : 1950) 2022 Oct 15;209(8):1481-1491
Journal of immunology (Baltimore, Md. : 1950) 2022 Oct 15;209(8):1481-1491
Control of HIV-1 Replication by CD8(+) T Cells Specific for Two Novel Pol Protective Epitopes in HIV-1 Subtype A/E Infection.
Nguyen HT, Kuse N, Zhang Y, Murakoshi H, Maeda Y, Tamura Y, Maruyama R, Tran GV, Nguyen TV, Nguyen KV, Oka S, Chikata T, Takiguchi M
Journal of virology 2022 Oct 12;96(19):e0081122
Journal of virology 2022 Oct 12;96(19):e0081122
S100A8-mediated metabolic adaptation controls HIV-1 persistence in macrophages in vivo.
Real F, Zhu A, Huang B, Belmellat A, Sennepin A, Vogl T, Ransy C, Revol M, Arrigucci R, Lombès A, Roth J, Gennaro ML, Bouillaud F, Cristofari S, Bomsel M
Nature communications 2022 Oct 11;13(1):5956
Nature communications 2022 Oct 11;13(1):5956
Peroxynitrite in the tumor microenvironment changes the profile of antigens allowing escape from cancer immunotherapy.
Tcyganov EN, Sanseviero E, Marvel D, Beer T, Tang HY, Hembach P, Speicher DW, Zhang Q, Donthireddy LR, Mostafa A, Tsyganova S, Pisarev V, Laufer T, Ignatov D, Ferrone S, Meyer C, Maby-El Hajjami H, Speiser DE, Altiok S, Antonia S, Xu X, Xu W, Zheng C, Schuchter LM, Amaravadi RK, Mitchell TC, Karakousis GC, Yuan Z, Montaner LJ, Celis E, Gabrilovich DI
Cancer cell 2022 Oct 10;40(10):1173-1189.e6
Cancer cell 2022 Oct 10;40(10):1173-1189.e6
Humoral and Cellular Immune Responses After a 3-dose Course of mRNA-1273 COVID-19 Vaccine in Kidney Transplant Recipients: A Prospective Cohort Study.
Cucchiari D, Egri N, Rodriguez-Espinosa D, Montagud-Marrahi E, Casals-Urquiza J, Del Risco-Zevallos J, Bodro M, Ventura-Aguiar P, Cofan F, Cacho J, Molina-Andujar A, Rovira J, Banon-Maneus E, José Ramirez-Bajo M, Pérez-Olmos A, Garcia-Pascual M, Pascal M, Vilella A, Trilla A, Palou E, Revuelta I, Juan M, Campistol JM, Oppenheimer F, Moreno A, Miró JM, Bayés B, Diekmann F
Transplantation direct 2022 Nov;8(11):e1389
Transplantation direct 2022 Nov;8(11):e1389
SARS-CoV-2 Spike-specific IFN-γ T-cell Response After COVID-19 Vaccination in Patients With Chronic Kidney Disease, on Dialysis, or Living With a Kidney Transplant.
Imhof C, Messchendorp AL, van der Heiden M, Baan CC, van der Molen RG, Remmerswaal EBM, de Vries RD, Diavatopoulos DA, Boerma A, Bakker FJ, Oosterhout E, Bemelman FJ, Hilbrands LB, Reinders MEJ, Gansevoort RT, Sanders JS, van Baarle D
Transplantation direct 2022 Nov;8(11):e1387
Transplantation direct 2022 Nov;8(11):e1387
Comparison of the rapidity of SARS-CoV-2 immune responses between primary and booster vaccination for COVID-19.
Kim JY, Kwon JS, Cha HH, Lim SY, Bae S, Kim SH
The Korean journal of internal medicine 2022 Nov;37(6):1234-1240
The Korean journal of internal medicine 2022 Nov;37(6):1234-1240
Immunogenicity and safety of two doses of SARS-CoV-2 mRNA vaccine in kidney transplant recipients with low-dose rituximab.
Takai S, Nishida H, Ito H, Fukuhara H, Nawano T, Narisawa T, Kanno H, Yagi M, Yamagishi A, Sakurai T, Naito S, Kato T, Morikane K, Tsuchiya N
International journal of urology : official journal of the Japanese Urological Association 2022 Nov;29(11):1279-1286
International journal of urology : official journal of the Japanese Urological Association 2022 Nov;29(11):1279-1286
Differential immune transcriptomic profiles between vaccinated and resolved HCV reinfected subjects.
Mazouz S, Salinas E, Bédard N, Filali A, Khedr O, Swadling L, Abdel-Hakeem MS, Siddique A, Barnes E, Bruneau J, Grakoui A, Shoukry NH
PLoS pathogens 2022 Nov;18(11):e1010968
PLoS pathogens 2022 Nov;18(11):e1010968
IFN-γ ELISpot in Severe Cutaneous Adverse Reactions to First-Line Antituberculosis Drugs in an HIV Endemic Setting.
Porter M, Choshi P, Pedretti S, Chimbetete T, Smith R, Meintjes G, Phillips E, Lehloenya R, Peter J
The Journal of investigative dermatology 2022 Nov;142(11):2920-2928.e5
The Journal of investigative dermatology 2022 Nov;142(11):2920-2928.e5
Shared Clavulanate and Tazobactam Antigenic Determinants Activate T-Cells from Hypersensitive Patients.
Ariza A, Jaruthamsophon K, Meng X, Labella M, Adair K, Tailor A, Sukasem C, Whitaker P, Peckham D, Pirmohamed M, Torres MJ, Naisbitt DJ
Chemical research in toxicology 2022 Nov 21;35(11):2122-2132
Chemical research in toxicology 2022 Nov 21;35(11):2122-2132
Synthetic selenium nanoparticles as co-adjuvant improved immune responses against methicillin-resistant Staphylococcus aureus.
Ranjbariyan A, Haghighat S, Yazdi MH, Arbabi Bidgoli S
World journal of microbiology & biotechnology 2022 Nov 19;39(1):16
World journal of microbiology & biotechnology 2022 Nov 19;39(1):16
Kinetics of immune responses elicited after three mRNA COVID-19 vaccine doses in predominantly antibody-deficient individuals.
Ainsua-Enrich E, Pedreño-Lopez N, Bracke C, Ávila-Nieto C, Rodríguez de la Concepción ML, Pradenas E, Trinité B, Marfil S, Miranda C, González S, Toledo R, Font M, Benet S, Escribà T, Jimenez-Moyano E, Peña R, Cedeño S, Prado JG, Mothe B, Brander C, Izquierdo-Useros N, Vergara-Alert J, Segalés J, Massanella M, Benitez RM, Romero A, Molina-Morant D, Blanco J, Clotet B, Mateu L, Pedro-Botet ML, Carrillo J
iScience 2022 Nov 18;25(11):105455
iScience 2022 Nov 18;25(11):105455
A comparative characterization of SARS-CoV-2-specific T cells induced by mRNA or inactive virus COVID-19 vaccines.
Lim JME, Hang SK, Hariharaputran S, Chia A, Tan N, Lee ES, Chng E, Lim PL, Young BE, Lye DC, Le Bert N, Bertoletti A, Tan AT
Cell reports. Medicine 2022 Nov 15;3(11):100793
Cell reports. Medicine 2022 Nov 15;3(11):100793
Additional heterologous versus homologous booster vaccination in immunosuppressed patients without SARS-CoV-2 antibody seroconversion after primary mRNA vaccination: a randomised controlled trial.
Bonelli M, Mrak D, Tobudic S, Sieghart D, Koblischke M, Mandl P, Kornek B, Simader E, Radner H, Perkmann T, Haslacher H, Mayer M, Hofer P, Redlich K, Husar-Memmer E, Fritsch-Stork R, Thalhammer R, Stiasny K, Winkler S, Smolen JS, Aberle JH, Zeitlinger M, Heinz LX, Aletaha D
Annals of the rheumatic diseases 2022 May;81(5):687-694
Annals of the rheumatic diseases 2022 May;81(5):687-694
Elevated CD21(low) B Cell Frequency Is a Marker of Poor Immunity to Pfizer-BioNTech BNT162b2 mRNA Vaccine Against SARS-CoV-2 in Patients with Common Variable Immunodeficiency.
Bergman P, Wullimann D, Gao Y, Wahren Borgström E, Norlin AC, Lind Enoksson S, Aleman S, Ljunggren HG, Buggert M, Smith CIE
Journal of clinical immunology 2022 May;42(4):716-727
Journal of clinical immunology 2022 May;42(4):716-727
Sensitive identification of neoantigens and cognate TCRs in human solid tumors.
Arnaud M, Chiffelle J, Genolet R, Navarro Rodrigo B, Perez MAS, Huber F, Magnin M, Nguyen-Ngoc T, Guillaume P, Baumgaertner P, Chong C, Stevenson BJ, Gfeller D, Irving M, Speiser DE, Schmidt J, Zoete V, Kandalaft LE, Bassani-Sternberg M, Bobisse S, Coukos G, Harari A
Nature biotechnology 2022 May;40(5):656-660
Nature biotechnology 2022 May;40(5):656-660
Immune responses against SARS-CoV-2 variants after two and three doses of vaccine in B-cell malignancies: UK PROSECO study.
Lim SH, Stuart B, Joseph-Pietras D, Johnson M, Campbell N, Kelly A, Jeffrey D, Turaj AH, Rolfvondenbaumen K, Galloway C, Wynn T, Coleman AR, Ward B, Long K, Coleman H, Mundy C, Bates AT, Ayres D, Lown R, Falconer J, Brake O, Batchelor J, Willimott V, Bowzyk Al-Naeeb A, Robinson L, O'Callaghan A, Collins GP, Menne T, Faust SN, Fox CP, Ahearne M, Johnson PWM, Davies AJ, Goldblatt D
Nature cancer 2022 May;3(5):552-564
Nature cancer 2022 May;3(5):552-564
Anti-SARS-CoV-2 vaccines in recipient and/or donor before allotransplant.
Jullien M, Coste-Burel M, Clemenceau B, Letailleur V, Guillaume T, Peterlin P, Garnier A, Bourgeois AL, Imbert BM, Ollier J, Grain A, Touzeau C, Moreau P, Béné MC, Vié H, Chevallier P
EJHaem 2022 May;3(2):484-487
EJHaem 2022 May;3(2):484-487
Safety and immunogenicity of heterologous boost immunization with an adenovirus type-5-vectored and protein-subunit-based COVID-19 vaccine (Convidecia/ZF2001): A randomized, observer-blinded, placebo-controlled trial.
Jin P, Guo X, Chen W, Ma S, Pan H, Dai L, Du P, Wang L, Jin L, Chen Y, Shi F, Liu J, Xu X, Zhang Y, Gao GF, Chen C, Feng J, Li J, Zhu F
PLoS medicine 2022 May;19(5):e1003953
PLoS medicine 2022 May;19(5):e1003953
A phenotypic signature that identifies neoantigen-reactive T cells in fresh human lung cancers.
Hanada KI, Zhao C, Gil-Hoyos R, Gartner JJ, Chow-Parmer C, Lowery FJ, Krishna S, Prickett TD, Kivitz S, Parkhurst MR, Wong N, Rae Z, Kelly MC, Goff SL, Robbins PF, Rosenberg SA, Yang JC
Cancer cell 2022 May 9;40(5):479-493.e6
Cancer cell 2022 May 9;40(5):479-493.e6
Systemic Cancer Therapy Does Not Significantly Impact Early Vaccine-Elicited SARS-CoV-2 Immunity in Patients with Solid Tumors.
Waickman AT, Lu J, Chase C, Fang H, McDowell E, Bingham E, Bogart J, Graziano S, Thomas SJ, Gentile T
Vaccines 2022 May 9;10(5)
Vaccines 2022 May 9;10(5)
Competent immune responses to SARS-CoV-2 variants in older adults following two doses of mRNA vaccination.
Jergović M, Uhrlaub JL, Watanabe M, Bradshaw CM, White LM, LaFleur BJ, Edwards T, Sprissler R, Worobey M, Bhattacharya D, Nikolich-Žugich J
Nature communications 2022 May 24;13(1):2891
Nature communications 2022 May 24;13(1):2891
Immunogenicity and safety of an intradermal ChAdOx1 nCoV-19 boost in a healthy population.
Pinpathomrat N, Intapiboon P, Seepathomnarong P, Ongarj J, Sophonmanee R, Hengprakop J, Surasombatpattana S, Uppanisakorn S, Mahasirimongkol S, Sawaengdee W, Phumiamorn S, Sapsutthipas S, Kongkamol C, Ingviya T, Sangsupawanich P, Chusri S
NPJ vaccines 2022 May 13;7(1):52
NPJ vaccines 2022 May 13;7(1):52
Functional in-vitro evaluation of the non-specific effects of BCG vaccination in a randomised controlled clinical study.
Wilkie M, Tanner R, Wright D, Lopez Ramon R, Beglov J, Riste M, Marshall JL, Harris SA, Bettencourt PJG, Hamidi A, van Diemen PM, Moss P, Satti I, Wyllie D, McShane H
Scientific reports 2022 May 12;12(1):7808
Scientific reports 2022 May 12;12(1):7808
Vaccines elicit highly conserved cellular immunity to SARS-CoV-2 Omicron.
Liu J, Chandrashekar A, Sellers D, Barrett J, Jacob-Dolan C, Lifton M, McMahan K, Sciacca M, VanWyk H, Wu C, Yu J, Collier AY, Barouch DH
Nature 2022 Mar;603(7901):493-496
Nature 2022 Mar;603(7901):493-496
Phospholipase activity of acyloxyacyl hydrolase induces IL-22-producing CD1a-autoreactive T cells in individuals with psoriasis.
Singh R, Chen YL, Ng SW, Cain D, Etherington R, Hardman C, Ogg G
European journal of immunology 2022 Mar;52(3):511-524
European journal of immunology 2022 Mar;52(3):511-524
Reverted exhaustion phenotype of circulating lymphocytes as immune correlate of anti-PD1 first-line treatment in Hodgkin lymphoma.
Garcia-Marquez MA, Thelen M, Reinke S, Keller D, Wennhold K, Lehmann J, Veldman J, Borchmann S, Rosenwald A, Sasse S, Diepstra A, Borchmann P, Engert A, Klapper W, von Bergwelt-Baildon M, Bröckelmann PJ, Schlößer HA
Leukemia 2022 Mar;36(3):760-771
Leukemia 2022 Mar;36(3):760-771
Activation of human γδ T cells and NK cells by Staphylococcal enterotoxins requires both monocytes and conventional T cells.
Mata Forsberg M, Arasa C, van Zwol W, Uzunçayir S, Schönbichler A, Regenthal P, Schelin J, Lindkvist-Petersson K, Björkander S, Sverremark-Ekström E
Journal of leukocyte biology 2022 Mar;111(3):597-609
Journal of leukocyte biology 2022 Mar;111(3):597-609
Enhanced antigen cross-presentation in human colorectal cancer-associated fibroblasts through upregulation of the lysosomal protease cathepsin S.
Harryvan TJ, Visser M, de Bruin L, Plug L, Griffioen L, Mulder A, van Veelen PA, van der Heden van Noort GJ, Jongsma ML, Meeuwsen MH, Wiertz EJ, Santegoets SJ, Hardwick JC, Van Hall T, Neefjes J, Van der Burg SH, Hawinkels LJ, Verdegaal EM
Journal for immunotherapy of cancer 2022 Mar;10(3)
Journal for immunotherapy of cancer 2022 Mar;10(3)
Development of a T cell-based immunodiagnostic system to effectively distinguish SARS-CoV-2 infection and COVID-19 vaccination status.
Yu ED, Wang E, Garrigan E, Goodwin B, Sutherland A, Tarke A, Chang J, Gálvez RI, Mateus J, Ramirez SI, Rawlings SA, Smith DM, Filaci G, Frazier A, Weiskopf D, Dan JM, Crotty S, Grifoni A, Sette A, da Silva Antunes R
Cell host & microbe 2022 Mar 9;30(3):388-399.e3
Cell host & microbe 2022 Mar 9;30(3):388-399.e3
Enhancement of Antiviral T-Cell Responses by Vitamin C Suggests New Strategies to Improve Manufacturing of Virus-Specific T Cells for Adoptive Immunotherapy.
Laubert M, Bonifacius A, Dragon AC, Mangare C, Blasczyk R, Huehn J, Eiz-Vesper B
Biology 2022 Mar 30;11(4)
Biology 2022 Mar 30;11(4)
Immunoescape of HIV-1 in Env-EL9 CD8 + T cell response restricted by HLA-B*14:02 in a Non progressor who lost twenty-seven years of HIV-1 control.
Moyano A, Blanch-Lombarte O, Tarancon-Diez L, Pedreño-Lopez N, Arenas M, Alvaro T, Casado C, Olivares I, Vera M, Rodriguez C, Del Romero J, López-Galíndez C, Ruiz-Mateos E, Prado JG, Pernas M
Retrovirology 2022 Mar 26;19(1):6
Retrovirology 2022 Mar 26;19(1):6
T cell reactivity to the SARS-CoV-2 Omicron variant is preserved in most but not all individuals.
Naranbhai V, Nathan A, Kaseke C, Berrios C, Khatri A, Choi S, Getz MA, Tano-Menka R, Ofoman O, Gayton A, Senjobe F, Zhao Z, St Denis KJ, Lam EC, Carrington M, Garcia-Beltran WF, Balazs AB, Walker BD, Iafrate AJ, Gaiha GD
Cell 2022 Mar 17;185(6):1041-1051.e6
Cell 2022 Mar 17;185(6):1041-1051.e6
Differential T cell immune responses to deamidated adeno-associated virus vector.
Bing SJ, Justesen S, Wu WW, Sajib AM, Warrington S, Baer A, Thorgrimsen S, Shen RF, Mazor R
Molecular therapy. Methods & clinical development 2022 Mar 10;24:255-267
Molecular therapy. Methods & clinical development 2022 Mar 10;24:255-267
Divergent trajectories of antiviral memory after SARS-CoV-2 infection.
Tomic A, Skelly DT, Ogbe A, O'Connor D, Pace M, Adland E, Alexander F, Ali M, Allott K, Azim Ansari M, Belij-Rammerstorfer S, Bibi S, Blackwell L, Brown A, Brown H, Cavell B, Clutterbuck EA, de Silva T, Eyre D, Lumley S, Flaxman A, Grist J, Hackstein CP, Halkerston R, Harding AC, Hill J, James T, Jay C, Johnson SA, Kronsteiner B, Lie Y, Linder A, Longet S, Marinou S, Matthews PC, Mellors J, Petropoulos C, Rongkard P, Sedik C, Silva-Reyes L, Smith H, Stockdale L, Taylor S, Thomas S, Tipoe T, Turtle L, Vieira VA, Wrin T, OPTIC Clinical Group, PITCH Study Group, C-MORE Group, Pollard AJ, Lambe T, Conlon CP, Jeffery K, Travis S, Goulder P, Frater J, Mentzer AJ, Stafford L, Carroll MW, James WS, Klenerman P, Barnes E, Dold C, Dunachie SJ
Nature communications 2022 Mar 10;13(1):1251
Nature communications 2022 Mar 10;13(1):1251
Antibody-Peptide Epitope Conjugates for Personalized Cancer Therapy.
Zhang S, Yan C, Millar DG, Yang Q, Heather JM, Langenbucher A, Morton LT, Sepulveda S, Alpert E, Whelton LR, Zarrella DT, Guo M, Minogue E, Lawrence MS, Rueda BR, Spriggs DR, Lu W, Langenau DM, Cobbold M
Cancer research 2022 Mar 1;82(5):773-784
Cancer research 2022 Mar 1;82(5):773-784
Robust SARS-CoV-2-specific and heterologous immune responses in vaccine-naïve residents of long-term care facilities who survive natural infection.
Tut G, Lancaster T, Butler MS, Sylla P, Spalkova E, Bone D, Kaur N, Bentley C, Amin U, Jadir AT, Hulme S, Ayodel M, Dowell AC, Pearce H, Zuo J, Margielewska-Davies S, Verma K, Nicol S, Begum J, Jinks E, Tut E, Bruton R, Krutikov M, Shrotri M, Giddings R, Azmi B, Fuller C, Irwin-Singer A, Hayward A, Copas A, Shallcross L, Moss P
Nature aging 2022 Jun;2(6):536-547
Nature aging 2022 Jun;2(6):536-547
Persistence of immune responses to the Sinopharm/BBIBP-CorV vaccine.
Jeewandara C, Aberathna IS, Pushpakumara PD, Kamaladasa A, Guruge D, Wijesinghe A, Gunasekera B, Ramu ST, Kuruppu H, Ranasinghe T, Dayarathna S, Dissanayake O, Gamalath N, Ekanayake D, Jayamali J, Jayathilaka D, Dissanayake M, Jayadas TT, Mudunkotuwa A, Somathilake G, Harvie M, Nimasha T, Danasekara S, Wijayamuni R, Schimanski L, Rijal P, Tan TK, Dong T, Townsend A, Ogg GS, Malavige GN
Immunity, inflammation and disease 2022 Jun;10(6):e621
Immunity, inflammation and disease 2022 Jun;10(6):e621
Targeting of Nrf2 improves antitumoral responses by human NK cells, TIL and CAR T cells during oxidative stress.
Renken S, Nakajima T, Magalhaes I, Mattsson J, Lundqvist A, Arnér ESJ, Kiessling R, Wickström SL
Journal for immunotherapy of cancer 2022 Jun;10(6)
Journal for immunotherapy of cancer 2022 Jun;10(6)
T Cell Immunogenicity, Gene Expression Profile, and Safety of Four Heterologous Prime-Boost Combinations of HIV Vaccine Candidates in Healthy Volunteers: Results of the Randomized Multi-Arm Phase I/II ANRS VRI01 Trial.
Richert L, Lelièvre JD, Lacabaratz C, Hardel L, Hocini H, Wiedemann A, Lucht F, Poizot-Martin I, Bauduin C, Diallo A, Rieux V, Rouch E, Surenaud M, Lefebvre C, Foucat E, Tisserand P, Guillaumat L, Durand M, Hejblum B, Launay O, Thiébaut R, Lévy Y, ANRS VRI01 Study Group
Journal of immunology (Baltimore, Md. : 1950) 2022 Jun 15;208(12):2663-2674
Journal of immunology (Baltimore, Md. : 1950) 2022 Jun 15;208(12):2663-2674
PD-1 and ICOS coexpression identifies tumor-reactive CD4+ T cells in human solid tumors.
Duhen R, Fesneau O, Samson KA, Frye AK, Beymer M, Rajamanickam V, Ross D, Tran E, Bernard B, Weinberg AD, Duhen T
The Journal of clinical investigation 2022 Jun 15;132(12)
The Journal of clinical investigation 2022 Jun 15;132(12)
Phase II Trial of Sipuleucel-T and Stereotactic Ablative Body Radiation for Patients with Metastatic Castrate-Resistant Prostate Cancer.
Hannan R, Dohopolski MJ, Pop LM, Mannala S, Watumull L, Mathews D, Gao A, Garant A, Arriaga YE, Bowman I, Chung JS, Wang J, Ariizumi K, Ahn C, Timmerman R, Courtney K
Biomedicines 2022 Jun 15;10(6)
Biomedicines 2022 Jun 15;10(6)
Cutting Edge: T Cell Responses to B.1.1.529 (Omicron) SARS-CoV-2 Variant Induced by COVID-19 Infection and/or mRNA Vaccination Are Largely Preserved.
Jergović M, Coplen CP, Uhrlaub JL, Beitel SC, Burgess JL, Lutrick K, Ellingson KD, Watanabe M, Nikolich-Žugich J
Journal of immunology (Baltimore, Md. : 1950) 2022 Jun 1;208(11):2461-2465
Journal of immunology (Baltimore, Md. : 1950) 2022 Jun 1;208(11):2461-2465
CAR T cells expressing a bacterial virulence factor trigger potent bystander antitumour responses in solid cancers.
Jin C, Ma J, Ramachandran M, Yu D, Essand M
Nature biomedical engineering 2022 Jul;6(7):830-841
Nature biomedical engineering 2022 Jul;6(7):830-841
Contribution of pre-existing neoantigen-specific T cells to a durable complete response after tumor-pulsed dendritic cell vaccine plus nivolumab therapy in a patient with metastatic salivary duct carcinoma.
Ichimiya S, Fujimura A, Masuda M, Masuda S, Yasumatsu R, Umebayashi M, Tanaka H, Koya N, Nakagawa S, Yew PY, Yoshimura S, Onishi H, Nakamura M, Nakamura Y, Morisaki T
Immunological investigations 2022 Jul;51(5):1498-1514
Immunological investigations 2022 Jul;51(5):1498-1514
Identification of shared neoantigens in esophageal carcinoma by the combination of comprehensive analysis of genomic data and in silico neoantigen prediction.
Yuan Y, Chen C, Liu S, Xiong H, Huang Y, Zhang X, Zhang X, Li B
Cellular immunology 2022 Jul;377:104537
Cellular immunology 2022 Jul;377:104537
Antibody and cellular immune responses following dual COVID-19 vaccination within infection-naive residents of long-term care facilities: an observational cohort study.
Tut G, Lancaster T, Sylla P, Butler MS, Kaur N, Spalkova E, Bentley C, Amin U, Jadir A, Hulme S, Ayodele M, Bone D, Tut E, Bruton R, Krutikov M, Giddings R, Shrotri M, Azmi B, Fuller C, Baynton V, Irwin-Singer A, Hayward A, Copas A, Shallcross L, Moss P
The lancet. Healthy longevity 2022 Jul;3(7):e461-e469
The lancet. Healthy longevity 2022 Jul;3(7):e461-e469
Safety and immunogenicity of anti-SARS CoV-2 vaccine SOBERANA 02 in homologous or heterologous scheme: Open label phase I and phase IIa clinical trials.
Eugenia-Toledo-Romaní M, Verdecia-Sánchez L, Rodríguez-González M, Rodríguez-Noda L, Valenzuela-Silva C, Paredes-Moreno B, Sánchez-Ramírez B, Pérez-Nicado R, González-Mugica R, Hernández-García T, Bergado-Baez G, Pi-Estopiñán F, Cruz-Sui O, Fraga-Quintero A, García-Montero M, Palenzuela-Díaz A, Baró-Román G, Mendoza-Hernández I, Fernandez-Castillo S, Climent-Ruiz Y, Santana-Mederos D, Ramírez Gonzalez U, García-Vega Y, Pérez-Massón B, Guang-Wu-Chen, Boggiano-Ayo T, Ojito-Magaz E, Rivera DG, Valdés-Balbín Y, García-Rivera D, Vérez-Bencomo V, SOBERANA Research Group, Gómez-Maceo Y, Reyes-Matienzo R, Manuel Coviella-Artime J, Morffi-Cinta I, Martínez-Pérez M, Castillo-Quintana I, Garcés-Hechavarría A, Valera-Fernández R, Martínez-Bedoya D, Garrido-Arteaga R, Cardoso-SanJorge F, Quintero Moreno L, Ontivero-Pino I, Teresa Pérez-Guevara M, Morales-García M, Noa-Romero E, Orosa-Vázquez I, Díaz-Hernández M, Rojas G, Tundidor Y, García-López E, Muñoz-Morejon Y, Galano-Frutos E, Rodríguez-Alvarez J, Arteaga A, Medina Nápoles M, Espi Ávila J, Fontanies Fernández M
Vaccine 2022 Jul 29;40(31):4220-4230
Vaccine 2022 Jul 29;40(31):4220-4230
Immunopotentiation by linking Hsp70 T-cell epitopes to Gag-Pol-Env-Nef-Rev multiepitope construct and increased IFN-gamma secretion in infected lymphocytes.
Akbari E, Ajdary S, Mirabzadeh Ardakani E, Agi E, Milani A, Seyedinkhorasani M, Khalaj V, Bolhassani A
Pathogens and disease 2022 Jul 28;80(1)
Pathogens and disease 2022 Jul 28;80(1)
Comparison of two T-cell assays to evaluate T-cell responses to SARS-CoV-2 following vaccination in naïve and convalescent healthcare workers.
Phillips E, Adele S, Malone T, Deeks A, Stafford L, Dobson SL, Amini A, Skelly D, Eyre D, Jeffery K, Conlon CP, Dold C, Otter A, D'Arcangelo S, Turtle L, PITCH Consortium, Klenerman P, Barnes E, Dunachie SJ
Clinical and experimental immunology 2022 Jul 22;209(1):90-98
Clinical and experimental immunology 2022 Jul 22;209(1):90-98
Local delivery of low-dose anti-CTLA-4 to the melanoma lymphatic basin leads to systemic T(reg) reduction and effector T cell activation.
van Pul KM, Notohardjo JCL, Fransen MF, Koster BD, Stam AGM, Chondronasiou D, Lougheed SM, Bakker J, Kandiah V, van den Tol MP, Jooss K, Vuylsteke RJCLM, van den Eertwegh AJM, de Gruijl TD
Science immunology 2022 Jul 15;7(73):eabn8097
Science immunology 2022 Jul 15;7(73):eabn8097
Persistence of immunity and impact of third dose of inactivated COVID-19 vaccine against emerging variants.
Vadrevu KM, Ganneru B, Reddy S, Jogdand H, Raju D, Sapkal G, Yadav P, Reddy P, Verma S, Singh C, Redkar SV, Gillurkar CS, Kushwaha JS, Mohapatra S, Bhate A, Rai SK, Ella R, Abraham P, Prasad S, Ella K
Scientific reports 2022 Jul 14;12(1):12038
Scientific reports 2022 Jul 14;12(1):12038
Immunogenicity and Reactogenicity of Ad26.COV2.S in Korean Adults: A Prospective Cohort Study.
Hyun H, Choi MJ, Heo JY, Seo YB, Nham E, Yoon JG, Seong H, Noh JY, Cheong HJ, Kim WJ, Choi JY, Lee YJ, Lee HW, Kim SS, Kim B, Song JY
Journal of Korean medical science 2022 Jul 11;37(27):e210
Journal of Korean medical science 2022 Jul 11;37(27):e210
A COVID-19 peptide vaccine for the induction of SARS-CoV-2 T cell immunity.
Heitmann JS, Bilich T, Tandler C, Nelde A, Maringer Y, Marconato M, Reusch J, Jäger S, Denk M, Richter M, Anton L, Weber LM, Roerden M, Bauer J, Rieth J, Wacker M, Hörber S, Peter A, Meisner C, Fischer I, Löffler MW, Karbach J, Jäger E, Klein R, Rammensee HG, Salih HR, Walz JS
Nature 2022 Jan;601(7894):617-622
Nature 2022 Jan;601(7894):617-622
Pre-existing polymerase-specific T cells expand in abortive seronegative SARS-CoV-2.
Swadling L, Diniz MO, Schmidt NM, Amin OE, Chandran A, Shaw E, Pade C, Gibbons JM, Le Bert N, Tan AT, Jeffery-Smith A, Tan CCS, Tham CYL, Kucykowicz S, Aidoo-Micah G, Rosenheim J, Davies J, Johnson M, Jensen MP, Joy G, McCoy LE, Valdes AM, Chain BM, Goldblatt D, Altmann DM, Boyton RJ, Manisty C, Treibel TA, Moon JC, COVIDsortium Investigators, van Dorp L, Balloux F, McKnight Á, Noursadeghi M, Bertoletti A, Maini MK
Nature 2022 Jan;601(7891):110-117
Nature 2022 Jan;601(7891):110-117
T-cell and antibody responses to first BNT162b2 vaccine dose in previously infected and SARS-CoV-2-naive UK health-care workers: a multicentre prospective cohort study.
Angyal A, Longet S, Moore SC, Payne RP, Harding A, Tipton T, Rongkard P, Ali M, Hering LM, Meardon N, Austin J, Brown R, Skelly D, Gillson N, Dobson SL, Cross A, Sandhar G, Kilby JA, Tyerman JK, Nicols AR, Spegarova JS, Mehta H, Hornsby H, Whitham R, Conlon CP, Jeffery K, Goulder P, Frater J, Dold C, Pace M, Ogbe A, Brown H, Ansari MA, Adland E, Brown A, Chand M, Shields A, Matthews PC, Hopkins S, Hall V, James W, Rowland-Jones SL, Klenerman P, Dunachie S, Richter A, Duncan CJA, Barnes E, Carroll M, Turtle L, de Silva TI, PITCH Consortium
The Lancet. Microbe 2022 Jan;3(1):e21-e31
The Lancet. Microbe 2022 Jan;3(1):e21-e31
Children develop robust and sustained cross-reactive spike-specific immune responses to SARS-CoV-2 infection.
Dowell AC, Butler MS, Jinks E, Tut G, Lancaster T, Sylla P, Begum J, Bruton R, Pearce H, Verma K, Logan N, Tyson G, Spalkova E, Margielewska-Davies S, Taylor GS, Syrimi E, Baawuah F, Beckmann J, Okike IO, Ahmad S, Garstang J, Brent AJ, Brent B, Ireland G, Aiano F, Amin-Chowdhury Z, Jones S, Borrow R, Linley E, Wright J, Azad R, Waiblinger D, Davis C, Thomson EC, Palmarini M, Willett BJ, Barclay WS, Poh J, Amirthalingam G, Brown KE, Ramsay ME, Zuo J, Moss P, Ladhani S
Nature immunology 2022 Jan;23(1):40-49
Nature immunology 2022 Jan;23(1):40-49
CD161 expression and regulation defines rapidly responding effector CD4+ T cells associated with improved survival in HPV16-associated tumors.
Duurland CL, Santegoets SJ, Abdulrahman Z, Loof NM, Sturm G, Wesselink TH, Arens R, Boekestijn S, Ehsan I, van Poelgeest MIE, Finotello F, Hackl H, Trajanoski Z, Ten Dijke P, Braud VM, Welters MJP, van der Burg SH
Journal for immunotherapy of cancer 2022 Jan;10(1)
Journal for immunotherapy of cancer 2022 Jan;10(1)
Gut commensal Limosilactobacillus reuteri induces atypical memory-like phenotype in human dendritic cells in vitro.
Lasaviciute G, Barz M, van der Heiden M, Arasa C, Tariq K, Quin J, Östlund Farrants AK, Sverremark-Ekström E
Gut microbes 2022 Jan-Dec;14(1):2045046
Gut microbes 2022 Jan-Dec;14(1):2045046
Towards large-scale identification of HLA-restricted T cell epitopes from four vaccine candidate antigens in a malaria endemic community in Ghana.
Kusi KA, Ofori EA, Akyea-Mensah K, Kyei-Baafour E, Frimpong A, Ennuson NA, Belmonte M, Ganeshan H, Huang J, Amoah LE, Villasante E, Sedegah M
Vaccine 2022 Jan 31;40(5):757-764
Vaccine 2022 Jan 31;40(5):757-764
Vaccines Elicit Highly Cross-Reactive Cellular Immunity to the SARS-CoV-2 Omicron Variant.
Liu J, Chandrashekar A, Sellers D, Barrett J, Lifton M, McMahan K, Sciacca M, VanWyk H, Wu C, Yu J, Collier AY, Barouch DH
medRxiv : the preprint server for health sciences 2022 Jan 3;
medRxiv : the preprint server for health sciences 2022 Jan 3;
Two Distinct Mechanisms Leading to Loss of Virological Control in the Rare Group of Antiretroviral Therapy-Naive, Transiently Aviremic Children Living with HIV.
Vieira VA, Adland E, Grayson NE, Csala A, Richards F, Dacon C, Athavale R, Tsai MH, D'Souza R, Muenchhoff M, Bonsall D, Jooste P, Goulder PJR
Journal of virology 2022 Jan 26;96(2):e0153521
Journal of virology 2022 Jan 26;96(2):e0153521
T-cells of invasive candidiasis patients show patterns of T-cell-exhaustion suggesting checkpoint blockade as treatment option.
Mellinghoff SC, Thelen M, Bruns C, Garcia-Marquez M, Hartmann P, Lammertz T, Lehmann J, Nowag A, Stemler J, Wennhold K, Cornely OA, von Bergwelt-Baildon MS, Schlößer HA
The Journal of infection 2022 Feb;84(2):237-247
The Journal of infection 2022 Feb;84(2):237-247
Primary immune responses are negatively impacted by persistent herpesvirus infections in older people: results from an observational study on healthy subjects and a vaccination trial on subjects aged more than 70 years old.
Nicoli F, Clave E, Wanke K, von Braun A, Bondet V, Alanio C, Douay C, Baque M, Lependu C, Marconi P, Stiasny K, Heinz FX, Muetsch M, Duffy D, Boddaert J, Sauce D, Toubert A, Karrer U, Appay V
EBioMedicine 2022 Feb;76:103852
EBioMedicine 2022 Feb;76:103852
SARS-CoV-2 specific cellular response following COVID-19 vaccination in patients with chronic lymphocytic leukemia.
Mellinghoff SC, Robrecht S, Mayer L, Weskamm LM, Dahlke C, Gruell H, Vanshylla K, Schlösser HA, Thelen M, Fink AM, Fischer K, Klein F, Addo MM, Eichhorst B, Hallek M, Langerbeins P
Leukemia 2022 Feb;36(2):562-565
Leukemia 2022 Feb;36(2):562-565
Heterologous AD5-nCOV plus CoronaVac versus homologous CoronaVac vaccination: a randomized phase 4 trial.
Li J, Hou L, Guo X, Jin P, Wu S, Zhu J, Pan H, Wang X, Song Z, Wan J, Cui L, Li J, Chen Y, Wang X, Jin L, Liu J, Shi F, Xu X, Zhu T, Chen W, Zhu F
Nature medicine 2022 Feb;28(2):401-409
Nature medicine 2022 Feb;28(2):401-409
Off-the-Shelf Third-Party Virus-Specific T Cell Therapy to Treat JC Polyomavirus Infection in Hematopoietic Stem Cell Transplantation Recipients.
Rubinstein JD, Jodele S, Heyenbruch D, Wilhelm J, Thomas S, Lutzko C, Zhu X, Leemhuis T, Cancelas JA, Keller M, Bollard CM, Hanley PJ, Boghdadly ZE, Mims A, Davies SM, Grimley MS, Nelson AS
Transplantation and cellular therapy 2022 Feb;28(2):116.e1-116.e7
Transplantation and cellular therapy 2022 Feb;28(2):116.e1-116.e7
WT1 epitope-specific IgG and IgM antibodies for immune-monitoring in patients with advanced sarcoma treated with a WT1 peptide cancer vaccine.
Alzaaqi S, Naka N, Hamada K, Hosen N, Kanegae M, Outani H, Adachi M, Imanishi R, Morii E, Iwai M, Nakata J, Fujiki F, Morimoto S, Nakajima H, Nishida S, Tsuboi A, Oka Y, Sugiyama H, Oji Y
Oncology letters 2022 Feb;23(2):65
Oncology letters 2022 Feb;23(2):65
SARS-CoV-2 memory B and T cell profiles in mild COVID-19 convalescent patients.
Gurevich M, Zilkha-Falb R, Sonis P, Magalashvili D, Menascu S, Flechter S, Dolev M, Mandel M, Achiron A
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 2022 Feb;115:208-214
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 2022 Feb;115:208-214
Short-Term Immunogenicity Profiles and Predictors for Suboptimal Immune Responses in Patients with End-Stage Kidney Disease Immunized with Inactivated SARS-CoV-2 Vaccine.
Boongird S, Chuengsaman P, Setthaudom C, Nongnuch A, Assanatham M, Phanprasert S, Kitpermkiat R, Kiertiburanakul S, Malathum K, Phuphuakrat A, Davenport A, Bruminhent J
Infectious diseases and therapy 2022 Feb;11(1):351-365
Infectious diseases and therapy 2022 Feb;11(1):351-365
Tumor RNA transfected DCs derived from iPS cells elicit cytotoxicity against cancer cells induced from colorectal cancer patients in vitro.
Maruoka S, Ojima T, Iwamoto H, Kitadani J, Tabata H, Tominaga S, Katsuda M, Hayata K, Takeuchi A, Yamaue H
Scientific reports 2022 Feb 28;12(1):3295
Scientific reports 2022 Feb 28;12(1):3295
Hepatitis B vaccine co-administration influences the heterologous effects of neonatal BCG vaccination in a sex-differential manner.
Pittet LF, Cox L, Freyne B, Germano S, Bonnici R, Gardiner K, Donath S, Collins CL, Casalaz D, Robins-Browne R, Flanagan KL, Messina NL, Curtis N
Vaccine 2022 Feb 23;40(9):1334-1341
Vaccine 2022 Feb 23;40(9):1334-1341
Characterization of Teicoplanin-Specific T-Cells from Drug Naïve Donors Expressing HLA-A*32:01.
Gardner J, Ogese M, Betts CJ, Pirmohamed M, Naisbitt DJ
Chemical research in toxicology 2022 Feb 21;35(2):199-202
Chemical research in toxicology 2022 Feb 21;35(2):199-202
Development of a skin- and neuro-attenuated live vaccine for varicella.
Wang W, Pan D, Fu W, Ye X, Han J, Yang L, Jia J, Liu J, Zhu R, Zhang Y, Liu C, Ye J, Selariu A, Que Y, Zhao Q, Wu T, Li Y, Zhang J, Cheng T, Zhu H, Xia N
Nature communications 2022 Feb 11;13(1):824
Nature communications 2022 Feb 11;13(1):824
Immunogenicity and safety of a fourth COVID-19 vaccination in rituximab-treated patients: an open-label extension study.
Mrak D, Simader E, Sieghart D, Mandl P, Radner H, Perkmann T, Haslacher H, Mayer M, Koblischke M, Hofer P, Göschl L, Kartnig F, Deimel T, Kerschbaumer A, Hummel T, Kornek B, Thalhammer R, Stiasny K, Winkler S, Smolen JS, Aberle JH, Aletaha D, Heinz LX, Bonelli M
Annals of the rheumatic diseases 2022 Dec;81(12):1750-1756
Annals of the rheumatic diseases 2022 Dec;81(12):1750-1756
Assessing anti-SARS-CoV-2 cellular immunity in 571 vaccines by using an IFN-γ release assay.
Wakui M, Uwamino Y, Yatabe Y, Nakagawa T, Sakai A, Kurafuji T, Shibata A, Tomita Y, Noguchi M, Tanabe A, Arai T, Ohno A, Yokota H, Uno S, Yamasawa W, Sato Y, Ikeda M, Yoshimura A, Hasegawa N, Saya H, Murata M
European journal of immunology 2022 Dec;52(12):1961-1971
European journal of immunology 2022 Dec;52(12):1961-1971
Safety, immunogenicity and effect on viral rebound of HTI vaccines in early treated HIV-1 infection: a randomized, placebo-controlled phase 1 trial.
Bailón L, Llano A, Cedeño S, Escribà T, Rosás-Umbert M, Parera M, Casadellà M, Lopez M, Pérez F, Oriol-Tordera B, Ruiz-Riol M, Coll J, Perez F, Rivero À, Leselbaum AR, McGowan I, Sengupta D, Wee EG, Hanke T, Paredes R, Alarcón-Soto Y, Clotet B, Noguera-Julian M, Brander C, Molto J, Mothe B, AELIX002 Study Group
Nature medicine 2022 Dec;28(12):2611-2621
Nature medicine 2022 Dec;28(12):2611-2621
Heterologous Prime-boost of SARS-CoV-2 inactivated vaccine and mRNA BNT162b2 among Healthy Thai Adolescents.
Puthanakit T, Nantanee R, Jaru-Ampornpan P, Chantasrisawad N, Sophonphan J, Meepuksom T, Jupimai T, Sodsai P, Anugulruengkitt S, Hirankarn N, Study Team
Vaccine: X 2022 Dec;12:100211
Vaccine: X 2022 Dec;12:100211
T cells of colorectal cancer patients' stimulated by neoantigenic and cryptic peptides better recognize autologous tumor cells.
Schwarz S, Schmitz J, Löffler MW, Ghosh M, Rammensee HG, Olshvang E, Markel M, Mockel-Tenbrinck N, Dzionek A, Krake S, Arslan B, Kampe KD, Wendt A, Bauer P, Mullins CS, Schlosser A, Linnebacher M
Journal for immunotherapy of cancer 2022 Dec;10(12)
Journal for immunotherapy of cancer 2022 Dec;10(12)
CD1a promotes systemic manifestations of skin inflammation.
Hardman CS, Chen YL, Wegrecki M, Ng SW, Murren R, Mangat D, Silva JP, Munro R, Chan WY, O'Dowd V, Doyle C, Mori P, Popplewell A, Rossjohn J, Lightwood D, Ogg GS
Nature communications 2022 Dec 7;13(1):7535
Nature communications 2022 Dec 7;13(1):7535
The Autophagy Receptor TAX1BP1 (T6BP) improves antigen presentation by MHC-II molecules.
Sarango G, Richetta C, Pereira M, Kumari A, Ghosh M, Bertrand L, Pionneau C, Le Gall M, Grégoire S, Jeger-Madiot R, Rosoy E, Subra F, Delelis O, Faure M, Esclatine A, Graff-Dubois S, Stevanović S, Manoury B, Ramirez BC, Moris A
EMBO reports 2022 Dec 6;23(12):e55470
EMBO reports 2022 Dec 6;23(12):e55470
An engineered SARS-CoV-2 receptor-binding domain produced in Pichia pastoris as a candidate vaccine antigen.
Limonta-Fernández M, Chinea-Santiago G, Martín-Dunn AM, Gonzalez-Roche D, Bequet-Romero M, Marquez-Perera G, González-Moya I, Canaan-Haden-Ayala C, Cabrales-Rico A, Espinosa-Rodríguez LA, Ramos-Gómez Y, Andujar-Martínez I, González-López LJ, de la Iglesia MP, Zamora-Sanchez J, Cruz-Sui O, Lemos-Pérez G, Cabrera-Herrera G, Valdes-Hernández J, Martinez-Diaz E, Pimentel-Vazquez E, Ayala-Avila M, Guillén-Nieto G
New biotechnology 2022 Dec 25;72:11-21
New biotechnology 2022 Dec 25;72:11-21
Durable spike-specific T cell responses after different COVID-19 vaccination regimens are not further enhanced by booster vaccination.
Maringer Y, Nelde A, Schroeder SM, Schuhmacher J, Hörber S, Peter A, Karbach J, Jäger E, Walz JS
Science immunology 2022 Dec 23;7(78):eadd3899
Science immunology 2022 Dec 23;7(78):eadd3899
Dynamics of Antibody and T Cell Immunity against SARS-CoV-2 Variants of Concern and the Impact of Booster Vaccinations in Previously Infected and Infection-Naïve Individuals.
Faas MR, Mak WA, Markus HY, van der Zwan EM, van der Vliet M, Koeleman JGM, Ong DSY
Vaccines 2022 Dec 13;10(12)
Vaccines 2022 Dec 13;10(12)
Immunogenicity, Immune Dynamics, and Subsequent Response to the Booster Dose of Heterologous versus Homologous Prime-Boost Regimens with Adenoviral Vector and mRNA SARS-CoV-2 Vaccine among Liver Transplant Recipients: A Prospective Study.
Sriphoosanaphan S, Suksawatamnuay S, Srisoonthorn N, Siripon N, Thaimai P, Ananchuensook P, Thanapirom K, Nonthasoot B, Hansasuta P, Komolmit P
Vaccines 2022 Dec 12;10(12)
Vaccines 2022 Dec 12;10(12)
T-cell responses to SARS-CoV-2 Omicron spike epitopes with mutations after the third booster dose of an inactivated vaccine.
Li Y, Wang X, Jin J, Ma Z, Liu Y, Zhang X, Su B
Journal of medical virology 2022 Aug;94(8):3998-4004
Journal of medical virology 2022 Aug;94(8):3998-4004
SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway.
Willett BJ, Grove J, MacLean OA, Wilkie C, De Lorenzo G, Furnon W, Cantoni D, Scott S, Logan N, Ashraf S, Manali M, Szemiel A, Cowton V, Vink E, Harvey WT, Davis C, Asamaphan P, Smollett K, Tong L, Orton R, Hughes J, Holland P, Silva V, Pascall DJ, Puxty K, da Silva Filipe A, Yebra G, Shaaban S, Holden MTG, Pinto RM, Gunson R, Templeton K, Murcia PR, Patel AH, Klenerman P, Dunachie S, PITCH Consortium, COVID-19 Genomics UK (COG-UK) Consortium, Haughney J, Robertson DL, Palmarini M, Ray S, Thomson EC
Nature microbiology 2022 Aug;7(8):1161-1179
Nature microbiology 2022 Aug;7(8):1161-1179
Blood Th17 cells and IL-17A as candidate biomarkers estimating the progression of cognitive impairment in stroke patients.
Lu T, Ma L, Xu Q, Wang X
Journal of clinical laboratory analysis 2022 Aug;36(8):e24581
Journal of clinical laboratory analysis 2022 Aug;36(8):e24581
Impaired humoral and cellular response to primary COVID-19 vaccination in patients less than 2 years after allogeneic bone marrow transplant.
Murray SM, Barbanti M, Campbell C, Brown A, Chen L, Dhanapal J, Tseu B, Pervaiz O, Peters L, Springett S, Danby R, Adele S, Phillips E, Malone T, Amini A, Stafford L, Deeks AS, Dunachie S, Klenerman P, Peniket A, Barnes E, Kesavan M
British journal of haematology 2022 Aug;198(4):668-679
British journal of haematology 2022 Aug;198(4):668-679
The phenotype of HLA-binding B cells from sensitized kidney transplant recipients correlates with clinically prognostic patterns of interferon-γ production against purified HLA proteins.
Burton H, McLaughlin L, Shiu KY, Shaw O, Mamode N, Spencer J, Dorling A
Kidney international 2022 Aug;102(2):355-369
Kidney international 2022 Aug;102(2):355-369
Safety and immunogenicity of a live-attenuated influenza virus vector-based intranasal SARS-CoV-2 vaccine in adults: randomised, double-blind, placebo-controlled, phase 1 and 2 trials.
Zhu F, Zhuang C, Chu K, Zhang L, Zhao H, Huang S, Su Y, Lin H, Yang C, Jiang H, Zang X, Liu D, Pan H, Hu Y, Liu X, Chen Q, Song Q, Quan J, Huang Z, Zhong G, Chen J, Han J, Sun H, Cui L, Li J, Chen Y, Zhang T, Ye X, Li C, Wu T, Zhang J, Xia NS
The Lancet. Respiratory medicine 2022 Aug;10(8):749-760
The Lancet. Respiratory medicine 2022 Aug;10(8):749-760
Safety and immunogenicity of heterologous boost immunisation with an orally administered aerosolised Ad5-nCoV after two-dose priming with an inactivated SARS-CoV-2 vaccine in Chinese adults: a randomised, open-label, single-centre trial.
Li JX, Wu SP, Guo XL, Tang R, Huang BY, Chen XQ, Chen Y, Hou LH, Liu JX, Zhong J, Pan HX, Shi FJ, Xu XY, Li ZP, Zhang XY, Cui LB, Tan WJ, Chen W, Zhu FC, CanSino COVID-19 Study Group
The Lancet. Respiratory medicine 2022 Aug;10(8):739-748
The Lancet. Respiratory medicine 2022 Aug;10(8):739-748
Prediction of Th1 and Cytotoxic T Lymphocyte Epitopes of Mycobacterium tuberculosis and Evaluation of Their Potential in the Diagnosis of Tuberculosis in a Mouse Model and in Humans.
Gong W, Liang Y, Wang J, Liu Y, Xue Y, Mi J, Li P, Wang X, Wang L, Wu X
Microbiology spectrum 2022 Aug 31;10(4):e0143822
Microbiology spectrum 2022 Aug 31;10(4):e0143822
SARS-CoV-2 vaccine-induced antibody and T cell response in SARS-CoV-1 survivors.
Duan LJ, Cui XM, Zhu KL, Yao L, Wang GL, Cao WC, Ma MJ
Cell reports 2022 Aug 30;40(9):111284
Cell reports 2022 Aug 30;40(9):111284
Protective Immunity of COVID-19 Vaccination with ChAdOx1 nCoV-19 Following Previous SARS-CoV-2 Infection: A Humoral and Cellular Investigation.
Azamor T, Horbach IS, Brito E Cunha D, Melgaço JG, Silva AMVD, Tubarão LN, Azevedo AS, Santos RT, Alves NDS, Machado TL, Silva J, Souza AF, Bayma C, Rocha VP, Frederico ABT, Dias BM, Setatino BP, Denani CB, Campos SPDC, Schwarcz WD, Sucupira MV, Mendes EP, Silva EDD, Barbosa de Lima SM, Ano Bom APD, Missailidis S
Viruses 2022 Aug 30;14(9)
Viruses 2022 Aug 30;14(9)
Adoptive Cellular Therapy with Autologous Tumor-Infiltrating Lymphocytes and T-cell Receptor-Engineered T Cells Targeting Common p53 Neoantigens in Human Solid Tumors.
Kim SP, Vale NR, Zacharakis N, Krishna S, Yu Z, Gasmi B, Gartner JJ, Sindiri S, Malekzadeh P, Deniger DC, Lowery FJ, Parkhurst MR, Ngo LT, Ray S, Li YF, Hill V, Florentin M, Masi RV, Paria BC, Levin N, Bera A, Hedges EA, Choi A, Chatani PD, Parikh AY, Levi S, Seitter S, Lu YC, Zheng Z, Prickett TD, Jia L, Hernandez JM, Hoang CD, Robbins PF, Goff SL, Sherry RM, Yang JC, Rosenberg SA
Cancer immunology research 2022 Aug 3;10(8):932-946
Cancer immunology research 2022 Aug 3;10(8):932-946
Analysis of the Specific Immune Response after the Third Dose of mRNA COVID-19 Vaccines in Organ Transplant Recipients: Possible Spike-S1 Reactive IgA Signature in Protection from SARS-CoV-2 Infection.
Miele M, Busà R, Russelli G, Sorrentino MC, Di Bella M, Timoneri F, Vitale G, Calzolari E, Vitulo P, Mularoni A, Conaldi PG, Bulati M
Microorganisms 2022 Aug 3;10(8)
Microorganisms 2022 Aug 3;10(8)
HLA-B∗46 associates with rapid HIV disease progression in Asian cohorts and prominent differences in NK cell phenotype.
Li SS, Hickey A, Shangguan S, Ehrenberg PK, Geretz A, Butler L, Kundu G, Apps R, Creegan M, Clifford RJ, Pinyakorn S, Eller LA, Luechai P, Gilbert PB, Holtz TH, Chitwarakorn A, Sacdalan C, Kroon E, Phanuphak N, de Souza M, Ananworanich J, O'Connell RJ, Robb ML, Michael NL, Vasan S, Thomas R
Cell host & microbe 2022 Aug 10;30(8):1173-1185.e8
Cell host & microbe 2022 Aug 10;30(8):1173-1185.e8
Adenoviral-based vaccine promotes neoantigen-specific CD8(+) T cell stemness and tumor rejection.
D'Alise AM, Brasu N, De Intinis C, Leoni G, Russo V, Langone F, Baev D, Micarelli E, Petiti L, Picelli S, Fakih M, Le DT, Overman MJ, Shields AF, Pedersen KS, Shah MA, Mukherjee S, Faivre T, Delaite P, Scarselli E, Pace L
Science translational medicine 2022 Aug 10;14(657):eabo7604
Science translational medicine 2022 Aug 10;14(657):eabo7604
Identification of four novel T cell autoantigens and personal autoreactive profiles in multiple sclerosis.
Bronge M, Högelin KA, Thomas OG, Ruhrmann S, Carvalho-Queiroz C, Nilsson OB, Kaiser A, Zeitelhofer M, Holmgren E, Linnerbauer M, Adzemovic MZ, Hellström C, Jelcic I, Liu H, Nilsson P, Hillert J, Brundin L, Fink K, Kockum I, Tengvall K, Martin R, Tegel H, Gräslund T, Al Nimer F, Guerreiro-Cacais AO, Khademi M, Gafvelin G, Olsson T, Grönlund H
Science advances 2022 Apr 29;8(17):eabn1823
Science advances 2022 Apr 29;8(17):eabn1823
In-situ scalable manufacturing of Epstein-Barr virus-specific T-cells using bioreactor with an expandable culture area (BECA).
Chen S, Bin Abdul Rahim AA, Wang WW, Cheong R, Prabhu AV, Tan JZY, Naing MW, Toh HC, Liu D
Scientific reports 2022 Apr 29;12(1):7045
Scientific reports 2022 Apr 29;12(1):7045
Impaired humoral and T cell response to vaccination against SARS-CoV-2 in chronic myeloproliferative neoplasm patients treated with ruxolitinib.
Harrington P, Doores KJ, Saunders J, de Lord M, Saha C, Lechmere T, Khan H, Lam HPJ, Reilly AO, Woodley C, Asirvatham S, Dillon R, Curto-Garcia N, Sullivan JO, Kordasti S, Raj K, Malim MH, Radia D, McLornan D, Harrison C, de Lavallade H
Blood cancer journal 2022 Apr 22;12(4):73
Blood cancer journal 2022 Apr 22;12(4):73
Characterization of immune responses in fully vaccinated individuals after breakthrough infection with the SARS-CoV-2 delta variant.
Collier AY, Brown CM, McMahan KA, Yu J, Liu J, Jacob-Dolan C, Chandrashekar A, Tierney D, Ansel JL, Rowe M, Sellers D, Ahmad K, Aguayo R, Anioke T, Gardner S, Siamatu M, Bermudez-Rivera L, Hacker MR, Madoff LC, Barouch DH
Science translational medicine 2022 Apr 20;14(641):eabn6150
Science translational medicine 2022 Apr 20;14(641):eabn6150
Dynamics of Neutralizing Antibody and T-Cell Responses to SARS-CoV-2 and Variants of Concern after Primary Immunization with CoronaVac and Booster with BNT162b2 or ChAdOx1 in Health Care Workers.
Jantarabenjakul W, Sodsai P, Chantasrisawad N, Jitsatja A, Ninwattana S, Thippamom N, Ruenjaiman V, Tan CW, Pradit R, Sophonphan J, Wacharapluesadee S, Wang LF, Puthanakit T, Hirankarn N, Putcharoen O
Vaccines 2022 Apr 19;10(5)
Vaccines 2022 Apr 19;10(5)
Enhanced Cross-Reactive and Polyfunctional Effector-Memory T Cell Responses by ICVAX-a Human PD1-Based Bivalent HIV-1 Gag-p41 Mosaic DNA Vaccine.
Chen SMY, Wong YC, Yim LY, Zhang H, Wang H, Lui GCY, Li X, Tang X, Cheng L, Du Y, Peng Q, Wang J, Kwok HY, Huang H, Lau TT, Chan DPC, Wong BCK, Liu L, Chakrabarti LA, Lee SS, Chen Z
Journal of virology 2022 Apr 13;96(7):e0216121
Journal of virology 2022 Apr 13;96(7):e0216121
Transcriptomic profiles of neoantigen-reactive T cells in human gastrointestinal cancers.
Zheng C, Fass JN, Shih YP, Gunderson AJ, Sanjuan Silva N, Huang H, Bernard BM, Rajamanickam V, Slagel J, Bifulco CB, Piening B, Newell PHA, Hansen PD, Tran E
Cancer cell 2022 Apr 11;40(4):410-423.e7
Cancer cell 2022 Apr 11;40(4):410-423.e7
Neoantigen-specific CD4(+) T cells in human melanoma have diverse differentiation states and correlate with CD8(+) T cell, macrophage, and B cell function.
Veatch JR, Lee SM, Shasha C, Singhi N, Szeto JL, Moshiri AS, Kim TS, Smythe K, Kong P, Fitzgibbon M, Jesernig B, Bhatia S, Tykodi SS, Hall ET, Byrd DR, Thompson JA, Pillarisetty VG, Duhen T, McGarry Houghton A, Newell E, Gottardo R, Riddell SR
Cancer cell 2022 Apr 11;40(4):393-409.e9
Cancer cell 2022 Apr 11;40(4):393-409.e9
T cell mediated immunity against influenza H5N1 nucleoprotein, matrix and hemagglutinin derived epitopes in H5N1 survivors and non-H5N1 subjects.
Noisumdaeng P, Roytrakul T, Prasertsopon J, Pooruk P, Lerdsamran H, Assanasen S, Kitphati R, Auewarakul P, Puthavathana P
PeerJ 2021;9:e11021
PeerJ 2021;9:e11021
Immune Characters and Plasticity of the Sentinel Lymph Node in Colorectal Cancer Patients.
Li X, Tang J, Du H, Wang X, Wu L, Hu P, Zhang H, Zhang R, Yang Y
Journal of immunology research 2021;2021:5516399
Journal of immunology research 2021;2021:5516399
Comparative analysis of the ex vivo IFN-gamma responses to CD8+ T cell epitopes within allelic forms of PfAMA1 in subjects with natural exposure to malaria.
Nlinwe ON, Ofori EA, Akyea-Mensah K, Kyei-Baafour E, Ganeshan H, Belmonte M, Peters B, Villasante E, Sedegah M, Kusi KA
PloS one 2021;16(9):e0257219
PloS one 2021;16(9):e0257219
Immune alterations in subacute sclerosing panencephalitis reflect an incompetent response to eliminate the measles virus.
Yentür SP, Demirbilek V, Gurses C, Baris S, Kuru U, Ayta S, Yapici Z, Adin-Cinar S, Uysal S, Celik Yilmaz G, Onal E, Cokar O, Saruhan-Direskeneli G
PloS one 2021;16(1):e0245077
PloS one 2021;16(1):e0245077
Final results regarding the addition of dendritic cell vaccines to neoadjuvant chemotherapy in early HER2-negative breast cancer patients: clinical and translational analysis.
Santisteban M, Solans BP, Hato L, Urrizola A, Mejías LD, Salgado E, Sánchez-Bayona R, Toledo E, Rodríguez-Spiteri N, Olartecoechea B, Idoate MA, López-Díaz de Cerio A, Inogés S
Therapeutic advances in medical oncology 2021;13:17588359211064653
Therapeutic advances in medical oncology 2021;13:17588359211064653
Oxidized-Desialylated Low-Density Lipoprotein Inhibits the Antitumor Functions of Lymphokine Activated Killer Cells.
Aguilar Díaz de León JS, Glenn HL, Knappenberger M, Borges CR
Journal of Cancer 2021;12(16):4993-5004
Journal of Cancer 2021;12(16):4993-5004
HPV-16 E7-Specific Cellular Immune Response in Women With Cervical Intraepithelial Lesion Contributes to Viral Clearance: A Cross-Sectional and Longitudinal Clinical Study.
Zhang L, Shi X, Zhang Q, Mao Z, Shi X, Zhou J, Jian A, Zhu R, Jiang S, Lu W
Frontiers in immunology 2021;12:768144
Frontiers in immunology 2021;12:768144
Adding Help to an HLA-A*24:02 Tumor-Reactive γδTCR Increases Tumor Control.
Johanna I, Hernández-López P, Heijhuurs S, Scheper W, Bongiovanni L, de Bruin A, Beringer DX, Oostvogels R, Straetemans T, Sebestyen Z, Kuball J
Frontiers in immunology 2021;12:752699
Frontiers in immunology 2021;12:752699
Latent CMV Infection Is Associated With Lower Influenza Virus-Specific Memory T-Cell Frequencies, but Not With an Impaired T-Cell Response to Acute Influenza Virus Infection.
van den Berg SPH, Lanfermeijer J, Jacobi RHJ, Hendriks M, Vos M, van Schuijlenburg R, Nanlohy NM, Borghans JAM, van Beek J, van Baarle D, de Wit J
Frontiers in immunology 2021;12:663664
Frontiers in immunology 2021;12:663664
Vγ9Vδ2 T Cells Concurrently Kill Cancer Cells and Cross-Present Tumor Antigens.
Holmen Olofsson G, Idorn M, Carnaz Simões AM, Aehnlich P, Skadborg SK, Noessner E, Debets R, Moser B, Met Ö, Thor Straten P
Frontiers in immunology 2021;12:645131
Frontiers in immunology 2021;12:645131
Differential Longevity of Memory CD4 and CD8 T Cells in a Cohort of the Mothers With a History of ZIKV Infection and Their Children.
Badolato-Corrêa J, Carvalho FR, Paiva IA, Familiar-Macedo D, Dias HG, Pauvolid-Corrêa A, Fernandes-Santos C, Lima MDRQ, Gandini M, Silva AA, Baeta Cavalcanti SM, de Oliveira SA, de Oliveira Vianna RA, de Azeredo EL, Cardoso CAA, Grifoni A, Sette A, Weiskopf D, de-Oliveira-Pinto LM
Frontiers in immunology 2021;12:610456
Frontiers in immunology 2021;12:610456
An immunogenic first-in-human immune modulatory vaccine with PD-L1 and PD-L2 peptides is feasible and shows early signs of efficacy in follicular lymphoma.
Klausen U, Grønne Dahlager Jørgensen N, Grauslund JH, Munir Ahmad S, Gang AO, Martinenaite E, Weis-Banke SE, Breinholt MF, Novotny GW, Kjeldsen JW, Orebo Holmström M, Pedersen LB, Poulsen CB, Hansen PB, Met Ö, Svane IM, Niemann CU, Pedersen LM, Andersen MH
Oncoimmunology 2021;10(1):1975889
Oncoimmunology 2021;10(1):1975889
Functional analysis of peripheral and intratumoral neoantigen-specific TCRs identified in a patient with melanoma.
Bräunlein E, Lupoli G, Füchsl F, Abualrous ET, de Andrade Krätzig N, Gosmann D, Wietbrock L, Lange S, Engleitner T, Lan H, Audehm S, Effenberger M, Boxberg M, Steiger K, Chang Y, Yu K, Atay C, Bassermann F, Weichert W, Busch DH, Rad R, Freund C, Antes I, Krackhardt AM
Journal for immunotherapy of cancer 2021 Sep;9(9)
Journal for immunotherapy of cancer 2021 Sep;9(9)
Assessment of commonly used methods to determine myelin-reactivity of T cells in multiple sclerosis.
von Essen MR, Ammitzbøll C, Börnsen L, Sellebjerg F
Clinical immunology (Orlando, Fla.) 2021 Sep;230:108817
Clinical immunology (Orlando, Fla.) 2021 Sep;230:108817
Distinct tumour antigen-specific T-cell immune response profiles at different hepatocellular carcinoma stages.
Zang C, Zhao Y, Qin L, Liu G, Sun J, Li K, Zhao Y, Sheng S, Zhang H, He N, Zhao P, Wang Q, Li X, Peng Y, Dong T, Zhang Y
BMC cancer 2021 Sep 8;21(1):1007
BMC cancer 2021 Sep 8;21(1):1007
Intradermal ChAdOx1 Vaccine Following Two CoronaVac Shots: A Case Report.
Singhatiraj E, Pongpirul K, Jongkaewwattana A, Hirankarn N
Vaccines 2021 Sep 4;9(9)
Vaccines 2021 Sep 4;9(9)
HPV16 E6-specific T cell response and HLA-A alleles are related to the prognosis of patients with cervical cancer.
Cai H, Feng Y, Fan P, Guo Y, Kuerban G, Chang C, Yao X, Peng Y, Wang R
Infectious agents and cancer 2021 Sep 16;16(1):61
Infectious agents and cancer 2021 Sep 16;16(1):61
Virus-specific T cells for adenovirus infection after stem cell transplantation are highly effective and class II HLA restricted.
Rubinstein JD, Zhu X, Leemhuis T, Pham G, Ray L, Emberesh S, Jodele S, Thomas S, Cancelas JA, Bollard CM, Hanley PJ, Keller MD, Grimley O, Clark D, Clark T, Lindestam Arlehamn CS, Sette A, Davies SM, Nelson AS, Grimley MS, Lutzko C
Blood advances 2021 Sep 14;5(17):3309-3321
Blood advances 2021 Sep 14;5(17):3309-3321
Monitoring cell-mediated immune responses in AAV gene therapy clinical trials using a validated IFN-γ ELISpot method.
Patton KS, Harrison MT, Long BR, Lau K, Holcomb J, Owen R, Kasprzyk T, Janetzki S, Zoog SJ, Vettermann C
Molecular therapy. Methods & clinical development 2021 Sep 10;22:183-195
Molecular therapy. Methods & clinical development 2021 Sep 10;22:183-195
A functional assay for serum detection of antibodies against SARS-CoV-2 nucleoprotein.
Albecka A, Clift D, Vaysburd M, Rhinesmith T, Caddy SL, Favara DM, Baxendale HE, James LC
The EMBO journal 2021 Sep 1;40(17):e108588
The EMBO journal 2021 Sep 1;40(17):e108588
Rapid measurement of SARS-CoV-2 spike T cells in whole blood from vaccinated and naturally infected individuals.
Tan AT, Lim JM, Le Bert N, Kunasegaran K, Chia A, Qui MD, Tan N, Chia WN, de Alwis R, Ying D, Sim JX, Ooi EE, Wang LF, Chen MI, Young BE, Hsu LY, Low JG, Lye DC, Bertoletti A
The Journal of clinical investigation 2021 Sep 1;131(17)
The Journal of clinical investigation 2021 Sep 1;131(17)
Defining the RBPome of primary T helper cells to elucidate higher-order Roquin-mediated mRNA regulation.
Hoefig KP, Reim A, Gallus C, Wong EH, Behrens G, Conrad C, Xu M, Kifinger L, Ito-Kureha T, Defourny KAY, Geerlof A, Mautner J, Hauck SM, Baumjohann D, Feederle R, Mann M, Wierer M, Glasmacher E, Heissmeyer V
Nature communications 2021 Sep 1;12(1):5208
Nature communications 2021 Sep 1;12(1):5208
SARS-CoV-2 vaccination in rituximab-treated patients: B cells promote humoral immune responses in the presence of T-cell-mediated immunity.
Mrak D, Tobudic S, Koblischke M, Graninger M, Radner H, Sieghart D, Hofer P, Perkmann T, Haslacher H, Thalhammer R, Winkler S, Blüml S, Stiasny K, Aberle JH, Smolen JS, Heinz LX, Aletaha D, Bonelli M
Annals of the rheumatic diseases 2021 Oct;80(10):1345-1350
Annals of the rheumatic diseases 2021 Oct;80(10):1345-1350
Boosting CAR T-cell responses in lymphoma by simultaneous targeting of CD40/4-1BB using oncolytic viral gene therapy.
Wenthe J, Naseri S, Labani-Motlagh A, Enblad G, Wikström KI, Eriksson E, Loskog A, Lövgren T
Cancer immunology, immunotherapy : CII 2021 Oct;70(10):2851-2865
Cancer immunology, immunotherapy : CII 2021 Oct;70(10):2851-2865
High-affinity neoantigens correlate with better prognosis and trigger potent antihepatocellular carcinoma (HCC) activity by activating CD39(+)CD8(+) T cells.
Liu T, Tan J, Wu M, Fan W, Wei J, Zhu B, Guo J, Wang S, Zhou P, Zhang H, Shi L, Li J
Gut 2021 Oct;70(10):1965-1977
Gut 2021 Oct;70(10):1965-1977
Rational design of a hydrolysis-resistant mycobacterial phosphoglycolipid antigen presented by CD1c to T cells.
Reijneveld JF, Marino L, Cao TP, Cheng TY, Dam D, Shahine A, Witte MD, Filippov DV, Suliman S, van der Marel GA, Moody DB, Minnaard AJ, Rossjohn J, Codée JDC, Van Rhijn I
The Journal of biological chemistry 2021 Oct;297(4):101197
The Journal of biological chemistry 2021 Oct;297(4):101197
Safety, pharmacokinetics and antiviral activity of PGT121, a broadly neutralizing monoclonal antibody against HIV-1: a randomized, placebo-controlled, phase 1 clinical trial.
Stephenson KE, Julg B, Tan CS, Zash R, Walsh SR, Rolle CP, Monczor AN, Lupo S, Gelderblom HC, Ansel JL, Kanjilal DG, Maxfield LF, Nkolola J, Borducchi EN, Abbink P, Liu J, Peter L, Chandrashekar A, Nityanandam R, Lin Z, Setaro A, Sapiente J, Chen Z, Sunner L, Cassidy T, Bennett C, Sato A, Mayer B, Perelson AS, deCamp A, Priddy FH, Wagh K, Giorgi EE, Yates NL, Arduino RC, DeJesus E, Tomaras GD, Seaman MS, Korber B, Barouch DH
Nature medicine 2021 Oct;27(10):1718-1724
Nature medicine 2021 Oct;27(10):1718-1724
Patients with autoimmune polyendocrine syndrome type 1 have an increased susceptibility to severe herpesvirus infections.
Hetemäki I, Laakso S, Välimaa H, Kleino I, Kekäläinen E, Mäkitie O, Arstila TP
Clinical immunology (Orlando, Fla.) 2021 Oct;231:108851
Clinical immunology (Orlando, Fla.) 2021 Oct;231:108851
HLA Class-II‒Restricted CD8(+) T Cells Contribute to the Promiscuous Immune Response in Dapsone-Hypersensitive Patients.
Zhao Q, Almutairi M, Tailor A, Lister A, Harper N, Line J, Meng X, Pratoomwun J, Jaruthamsophon K, Sukasem C, Sun Y, Sun L, Ogese MO, MacEwan DJ, Pirmohamed M, Liu J, Ostrov DA, Liu H, Zhang F, Naisbitt DJ
The Journal of investigative dermatology 2021 Oct;141(10):2412-2425.e2
The Journal of investigative dermatology 2021 Oct;141(10):2412-2425.e2
CD4+ T cells in the lungs of acute sarcoidosis patients recognize an Aspergillus nidulans epitope.
Greaves SA, Ravindran A, Santos RG, Chen L, Falta MT, Wang Y, Mitchell AM, Atif SM, Mack DG, Tinega AN, Maier LA, Dai S, Pinilla C, Grunewald J, Fontenot AP
The Journal of experimental medicine 2021 Oct 4;218(10)
The Journal of experimental medicine 2021 Oct 4;218(10)
The evaluation of novel oral vaccines based on self-amplifying RNA lipid nanparticles (saRNA LNPs), saRNA transfected Lactobacillus plantarum LNPs, and saRNA transfected Lactobacillus plantarum to neutralize SARS-CoV-2 variants alpha and delta.
Keikha R, Hashemi-Shahri SM, Jebali A
Scientific reports 2021 Oct 29;11(1):21308
Scientific reports 2021 Oct 29;11(1):21308
Novel HLA-B7-restricted human metapneumovirus epitopes enhance viral clearance in mice and are recognized by human CD8(+) T cells.
Miranda-Katz M, Erickson JJ, Lan J, Ecker A, Zhang Y, Joyce S, Williams JV
Scientific reports 2021 Oct 21;11(1):20769
Scientific reports 2021 Oct 21;11(1):20769
Innate-like Gene Expression of Lung-Resident Memory CD8(+) T Cells during Experimental Human Influenza: A Clinical Study.
Paterson S, Kar S, Ung SK, Gardener Z, Bergstrom E, Ascough S, Kalyan M, Zyla J, Maertzdorf J, Mollenkopf HJ, Weiner J, Jozwik A, Jarvis H, Jha A, Nicholson BP, Veldman T, Woods CW, Mallia P, Kon OM, Kaufmann SHE, Openshaw PJ, Chiu C
American journal of respiratory and critical care medicine 2021 Oct 1;204(7):826-841
American journal of respiratory and critical care medicine 2021 Oct 1;204(7):826-841
Empirical identification and validation of tumor-targeting T cell receptors from circulation using autologous pancreatic tumor organoids.
Meng Q, Xie S, Gray GK, Dezfulian MH, Li W, Huang L, Akshinthala D, Ferrer E, Conahan C, Perea Del Pino S, Grossman J, Elledge SJ, Hidalgo M, Muthuswamy SK
Journal for immunotherapy of cancer 2021 Nov;9(11)
Journal for immunotherapy of cancer 2021 Nov;9(11)
The cellular immune response against Epstein-Barr virus decreases during ocrelizumab treatment.
Pham HPT, Gupta R, Lindsey JW
Multiple sclerosis and related disorders 2021 Nov;56:103282
Multiple sclerosis and related disorders 2021 Nov;56:103282
SARS-CoV-2-reactive T-cell receptors isolated from convalescent COVID-19 patients confer potent T-cell effector function.
Brunk F, Moritz A, Nelde A, Bilich T, Casadei N, Fraschka SAK, Heitmann JS, Hörber S, Peter A, Rammensee HG, Singh H, Walz J, Maurer D, Wagner C
European journal of immunology 2021 Nov;51(11):2651-2664
European journal of immunology 2021 Nov;51(11):2651-2664
Immune responses to two and three doses of the BNT162b2 mRNA vaccine in adults with solid tumors.
Shroff RT, Chalasani P, Wei R, Pennington D, Quirk G, Schoenle MV, Peyton KL, Uhrlaub JL, Ripperger TJ, Jergović M, Dalgai S, Wolf A, Whitmer R, Hammad H, Carrier A, Scott AJ, Nikolich-Žugich J, Worobey M, Sprissler R, Dake M, LaFleur BJ, Bhattacharya D
Nature medicine 2021 Nov;27(11):2002-2011
Nature medicine 2021 Nov;27(11):2002-2011
DNA and modified vaccinia Ankara prime-boost vaccination generates strong CD8(+) T cell responses against minor histocompatibility antigen HA-1.
Eldershaw SA, Pearce H, Inman CF, Piper KP, Abbotts B, Stephens C, Nicol S, Croft W, Powell R, Begum J, Taylor G, Nunnick J, Walsh D, Sirovica M, Saddique S, Nagra S, Ferguson P, Moss P, Malladi R
British journal of haematology 2021 Nov;195(3):433-446
British journal of haematology 2021 Nov;195(3):433-446
The Safety and Immunologic Effectiveness of the Live Varicella-Zoster Vaccine in Patients Receiving Tumor Necrosis Factor Inhibitor Therapy : A Randomized Controlled Trial.
Curtis JR, Cofield SS, Bridges SL Jr, Bassler J, Deodhar A, Ford TL, Huffstutter J, Jankeel A, Kivitz A, Kamal S, Lindsey S, Messaoudi I, Mendoza N, Michaud K, Mikuls TR, Ridley D, Shergy W, Siegel SAR, Winthrop KL
Annals of internal medicine 2021 Nov;174(11):1510-1518
Annals of internal medicine 2021 Nov;174(11):1510-1518
Oncolytic herpes simplex virus type-1 expressing IL-12 efficiently replicates and kills human colorectal cancer cells.
Haghighi-Najafabadi N, Roohvand F, Shams Nosrati MS, Teimoori-Toolabi L, Azadmanesh K
Microbial pathogenesis 2021 Nov;160:105164
Microbial pathogenesis 2021 Nov;160:105164
Myeloid-derived suppressor cells and their association with vaccine immunogenicity in South African infants.
Kidzeru E, Gasper MA, Shao D, Edlefsen PT, Lejarcegui N, Havyarimana E, Urdahl K, Gantt S, Horton H, Jaspan H, Gervassi A
Journal of leukocyte biology 2021 Nov;110(5):939-950
Journal of leukocyte biology 2021 Nov;110(5):939-950
Immunogenicity and Safety of an Intradermal BNT162b2 mRNA Vaccine Booster after Two Doses of Inactivated SARS-CoV-2 Vaccine in Healthy Population.
Intapiboon P, Seepathomnarong P, Ongarj J, Surasombatpattana S, Uppanisakorn S, Mahasirimongkol S, Sawaengdee W, Phumiamorn S, Sapsutthipas S, Sangsupawanich P, Chusri S, Pinpathomrat N
Vaccines 2021 Nov 23;9(12)
Vaccines 2021 Nov 23;9(12)
Challenging the Conventional Interpretation of HCMV Seronegativity.
Waters S, Lee S, Irish A, Price P
Microorganisms 2021 Nov 18;9(11)
Microorganisms 2021 Nov 18;9(11)
The Role of In Vivo and Ex Vivo Diagnostic Tools in Severe Delayed Immune-Mediated Adverse Antibiotic Drug Reactions.
Copaescu A, Mouhtouris E, Vogrin S, James F, Chua KYL, Holmes NE, Douglas A, Slavin MA, Cleland H, Zubrinich C, Aung AK, Goh MSY, Phillips EJ, Trubiano JA, Australasian Registry of Severe Cutaneous Adverse Reactions (AUS-SCAR)
The journal of allergy and clinical immunology. In practice 2021 May;9(5):2010-2015.e4
The journal of allergy and clinical immunology. In practice 2021 May;9(5):2010-2015.e4
Pre-existing immune status associated with response to combination of sipuleucel-T and ipilimumab in patients with metastatic castration-resistant prostate cancer.
Sinha M, Zhang L, Subudhi S, Chen B, Marquez J, Liu EV, Allaire K, Cheung A, Ng S, Nguyen C, Friedlander TW, Aggarwal R, Spitzer M, Allison JP, Small EJ, Sharma P, Fong L
Journal for immunotherapy of cancer 2021 May;9(5)
Journal for immunotherapy of cancer 2021 May;9(5)
T cell mediated hypersensitivity to previously tolerated iodinated contrast media precipitated by introduction of atezolizumab.
Hammond S, Olsson-Brown A, Gardner J, Thomson P, Ali SE, Jolly C, Carr D, Ressel L, Pirmohamed M, Naisbitt D
Journal for immunotherapy of cancer 2021 May;9(5)
Journal for immunotherapy of cancer 2021 May;9(5)
Unique Cholangiocyte-Targeted IgM Autoantibodies Correlate With Poor Outcome in Biliary Atresia.
Luo Y, Brigham D, Bednarek J, Torres R, Wang D, Ahmad S, Mack CL
Hepatology (Baltimore, Md.) 2021 May;73(5):1855-1867
Hepatology (Baltimore, Md.) 2021 May;73(5):1855-1867
Weighting tumor-specific TCR repertoires as a classifier to stratify the immunotherapy delivery in non-small cell lung cancers.
Han J, Yu R, Duan J, Li J, Zhao W, Feng G, Bai H, Wang Y, Zhang X, Wan R, Xu J, Wang X, Guan Y, Xia X, Yao Z, Fei K, Carbone DP, Wang Z, Wang J
Science advances 2021 May;7(21)
Science advances 2021 May;7(21)
Stepwise Reversal of Immune Dysregulation Due to STAT1 Gain-of-Function Mutation Following Ruxolitinib Bridge Therapy and Transplantation.
Kayaoglu B, Kasap N, Yilmaz NS, Charbonnier LM, Geckin B, Akcay A, Eltan SB, Ozturk G, Ozen A, Karakoc-Aydiner E, Chatila TA, Gursel M, Baris S
Journal of clinical immunology 2021 May;41(4):769-779
Journal of clinical immunology 2021 May;41(4):769-779
Failure of Viral-Specific T Cells Administered in Pre-transplant Settings in Children with Inborn Errors of Immunity.
Alonso L, Méndez-Echevarría A, Rudilla F, Mozo Y, Soler-Palacin P, Sisinni L, Bueno D, Riviere J, de Paz R, Sánchez-Zapardiel E, Querol S, Rodriguez-Pena R, López-Granados E, Gimeno R, Díaz de Heredia C, Pérez-Martínez A
Journal of clinical immunology 2021 May;41(4):748-755
Journal of clinical immunology 2021 May;41(4):748-755
Combined inhibition of PD-1/PD-L1, Lag-3, and Tim-3 axes augments antitumor immunity in gastric cancer-T cell coculture models.
Mimura K, Kua LF, Xiao JF, Asuncion BR, Nakayama Y, Syn N, Fazreen Z, Soong R, Kono K, Yong WP
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2021 May;24(3):611-623
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2021 May;24(3):611-623
Targeted Delivery of BZLF1 to DEC205 Drives EBV-Protective Immunity in a Spontaneous Model of EBV-Driven Lymphoproliferative Disease.
Ahmed EH, Brooks E, Sloan S, Schlotter S, Jeney F, Hale C, Mao C, Zhang X, McLaughlin E, Shindiapina P, Shire S, Das M, Prouty A, Lozanski G, Mamuye AT, Abebe T, Alinari L, Caligiuri MA, Baiocchi RA
Vaccines 2021 May 26;9(6)
Vaccines 2021 May 26;9(6)
Pre-existing T Cell Memory against Zika Virus.
Schouest B, Grifoni A, Pham J, Mateus J, Sydney J, Brien JD, De Silva AD, Balmaseda A, Harris E, Sette A, Weiskopf D
Journal of virology 2021 May 24;95(12)
Journal of virology 2021 May 24;95(12)
Quality Verification with a Cluster-Controlled Manufacturing System to Generate Monocyte-Derived Dendritic Cells.
Kawaguchi H, Sakamoto T, Koya T, Togi M, Date I, Watanabe A, Yoshida K, Kato T, Nakamura Y, Ishigaki Y, Shimodaira S
Vaccines 2021 May 20;9(5)
Vaccines 2021 May 20;9(5)
Persistent COVID-19 Symptoms Minimally Impact the Development of SARS-CoV-2-Specific T Cell Immunity.
Fang H, Wegman AD, Ripich K, Friberg H, Currier JR, Thomas SJ, Endy TP, Waickman AT
Viruses 2021 May 15;13(5)
Viruses 2021 May 15;13(5)
Highly conserved, non-human-like, and cross-reactive SARS-CoV-2 T cell epitopes for COVID-19 vaccine design and validation.
Meyers LM, Gutiérrez AH, Boyle CM, Terry F, McGonnigal BG, Salazar A, Princiotta MF, Martin WD, De Groot AS, Moise L
NPJ vaccines 2021 May 13;6(1):71
NPJ vaccines 2021 May 13;6(1):71
A phase 1, single centre, open label, escalating dose study to assess the safety, tolerability and immunogenicity of a therapeutic human papillomavirus (HPV) DNA vaccine (AMV002) for HPV-associated head and neck cancer (HNC).
Chandra J, Woo WP, Finlayson N, Liu HY, McGrath M, Ladwa R, Brauer M, Xu Y, Hanson S, Panizza B, Frazer IH, Porceddu SV
Cancer immunology, immunotherapy : CII 2021 Mar;70(3):743-753
Cancer immunology, immunotherapy : CII 2021 Mar;70(3):743-753
Clinical Trial of a Cancer Vaccine Targeting VEGF and KIF20A in Advanced Biliary Tract Cancer.
Murahashi M, Tsuruta T, Yamada K, Hijikata Y, Ogata H, Kishimoto J, Yoshimura S, Hikichi T, Nakanishi Y, Tani K
Anticancer research 2021 Mar;41(3):1485-1496
Anticancer research 2021 Mar;41(3):1485-1496
Resident and circulating memory T cells persist for years in melanoma patients with durable responses to immunotherapy.
Han J, Zhao Y, Shirai K, Molodtsov A, Kolling FW, Fisher JL, Zhang P, Yan S, Searles TG, Bader JM, Gui J, Cheng C, Ernstoff MS, Turk MJ, Angeles CV
Nature cancer 2021 Mar;2(3):300-311
Nature cancer 2021 Mar;2(3):300-311
The mutational load and a T-cell inflamed tumour phenotype identify ovarian cancer patients rendering tumour-reactive T cells from PD-1(+) tumour-infiltrating lymphocytes.
Salas-Benito D, Conde E, Tamayo-Uria I, Mancheño U, Elizalde E, Garcia-Ros D, Aramendia JM, Muruzabal JC, Alcaide J, Guillen-Grima F, Minguez JA, Amores-Tirado J, Gonzalez-Martin A, Sarobe P, Lasarte JJ, Ponz-Sarvise M, De Andrea CE, Hervas-Stubbs S
British journal of cancer 2021 Mar;124(6):1138-1149
British journal of cancer 2021 Mar;124(6):1138-1149
Shared recognition of citrullinated tenascin-C peptides by T and B cells in rheumatoid arthritis.
Song J, Schwenzer A, Wong A, Turcinov S, Rims C, Martinez LR, Arribas-Layton D, Gerstner C, Muir VS, Midwood KS, Malmström V, James EA, Buckner JH
JCI insight 2021 Mar 8;6(5)
JCI insight 2021 Mar 8;6(5)
SARS-CoV-2 mutations in MHC-I-restricted epitopes evade CD8(+) T cell responses.
Agerer B, Koblischke M, Gudipati V, Montaño-Gutierrez LF, Smyth M, Popa A, Genger JW, Endler L, Florian DM, Mühlgrabner V, Graninger M, Aberle SW, Husa AM, Shaw LE, Lercher A, Gattinger P, Torralba-Gombau R, Trapin D, Penz T, Barreca D, Fae I, Wenda S, Traugott M, Walder G, Pickl WF, Thiel V, Allerberger F, Stockinger H, Puchhammer-Stöckl E, Weninger W, Fischer G, Hoepler W, Pawelka E, Zoufaly A, Valenta R, Bock C, Paster W, Geyeregger R, Farlik M, Halbritter F, Huppa JB, Aberle JH, Bergthaler A
Science immunology 2021 Mar 4;6(57)
Science immunology 2021 Mar 4;6(57)
Immune memory in convalescent patients with asymptomatic or mild COVID-19.
Long QX, Jia YJ, Wang X, Deng HJ, Cao XX, Yuan J, Fang L, Cheng XR, Luo C, He AR, Tang XJ, Hu JL, Hu Y, Tang N, Cai XF, Wang DQ, Hu J, Qiu JF, Liu BZ, Chen J, Huang AL
Cell discovery 2021 Mar 25;7(1):18
Cell discovery 2021 Mar 25;7(1):18
Stability of interleukin-1β, -4, -6, -8, -10, -13, interferon-γ and tumor necrosis factor-α in human sera after repetitive freeze-thaw cycles and long storage.
Kordulewska NK, Topa J, Tańska M, Cieślińska A, Fiedorowicz E, Jarmołowska B
Journal of pharmaceutical and biomedical analysis 2021 Mar 20;196:113900
Journal of pharmaceutical and biomedical analysis 2021 Mar 20;196:113900
T Cells Specific for a Mycobacterial Glycolipid Expand after Intravenous Bacillus Calmette-Guérin Vaccination.
Layton ED, Barman S, Wilburn DB, Yu KKQ, Smith MT, Altman JD, Scriba TJ, Tahiri N, Minnaard AJ, Roederer M, Seder RA, Darrah PA, Seshadri C
Journal of immunology (Baltimore, Md. : 1950) 2021 Mar 15;206(6):1240-1250
Journal of immunology (Baltimore, Md. : 1950) 2021 Mar 15;206(6):1240-1250
Persistence of SARS-CoV-2-specific B and T cell responses in convalescent COVID-19 patients 6-8 months after the infection.
Sherina N, Piralla A, Du L, Wan H, Kumagai-Braesch M, Andréll J, Braesch-Andersen S, Cassaniti I, Percivalle E, Sarasini A, Bergami F, Di Martino R, Colaneri M, Vecchia M, Sambo M, Zuccaro V, Bruno R, Sachs M, Oggionni T, Meloni F, Abolhassani H, Bertoglio F, Schubert M, Byrne-Steele M, Han J, Hust M, Xue Y, Hammarström L, Baldanti F, Marcotte H, Pan-Hammarström Q
Med (New York, N.Y.) 2021 Mar 12;2(3):281-295.e4
Med (New York, N.Y.) 2021 Mar 12;2(3):281-295.e4
Two Cases of anti-PIT-1 Hypophysitis Exhibited as a Form of Paraneoplastic Syndrome not Associated With Thymoma.
Kanie K, Iguchi G, Inuzuka M, Sakaki K, Bando H, Urai S, Shichi H, Fujita Y, Matsumoto R, Suda K, Yamamoto M, Fukuoka H, Taniguchi T, Ogawa W, Takahashi Y
Journal of the Endocrine Society 2021 Mar 1;5(3):bvaa194
Journal of the Endocrine Society 2021 Mar 1;5(3):bvaa194
TGM4: an immunogenic prostate-restricted antigen.
Lopez-Bujanda ZA, Obradovic A, Nirschl TR, Crowley L, Macedo R, Papachristodoulou A, O'Donnell T, Laserson U, Zarif JC, Reshef R, Yuan T, Soni MK, Antonarakis ES, Haffner MC, Larman HB, Shen MM, Muranski P, Drake CG
Journal for immunotherapy of cancer 2021 Jun;9(6)
Journal for immunotherapy of cancer 2021 Jun;9(6)
Circulating leukocyte-platelet complexes as a predictive biomarker for the development of immune-related adverse events in advanced non-small cell lung cancer patients receiving anti-PD-(L)1 blocking agents.
Zamora C, Riudavets M, Anguera G, Alserawan L, Sullivan I, Barba A, Serra J, Ortiz MA, Gallardo P, Perea L, Gavira J, Barnadas A, Majem M, Vidal S
Cancer immunology, immunotherapy : CII 2021 Jun;70(6):1691-1704
Cancer immunology, immunotherapy : CII 2021 Jun;70(6):1691-1704
CD52/GPI- T-Cells Are Enriched for Alloreactive Specificity and Predict Acute Graft-Versus-Host-Disease After Stem Cell Transplantation.
Kinsella FA, Inman CF, Croft W, Zuo J, Pearce H, Barbieri S, Craddock C, Malladi R, Moss P
Transplantation and cellular therapy 2021 Jun;27(6):475.e1-475.e9
Transplantation and cellular therapy 2021 Jun;27(6):475.e1-475.e9
Whole blood interleukin-2 release test to detect and characterize rare circulating gluten-specific T cell responses in coeliac disease.
Anderson RP, Goel G, Hardy MY, Russell AK, Wang S, Szymczak E, Zhang R, Goldstein KE, Neff K, Truitt KE, Williams LJ, Dzuris JL, Tye-Din JA
Clinical and experimental immunology 2021 Jun;204(3):321-334
Clinical and experimental immunology 2021 Jun;204(3):321-334
Deep learning boosts sensitivity of mass spectrometry-based immunopeptidomics.
Wilhelm M, Zolg DP, Graber M, Gessulat S, Schmidt T, Schnatbaum K, Schwencke-Westphal C, Seifert P, de Andrade Krätzig N, Zerweck J, Knaute T, Bräunlein E, Samaras P, Lautenbacher L, Klaeger S, Wenschuh H, Rad R, Delanghe B, Huhmer A, Carr SA, Clauser KR, Krackhardt AM, Reimer U, Kuster B
Nature communications 2021 Jun 7;12(1):3346
Nature communications 2021 Jun 7;12(1):3346
Cellular Immune Response Induced by DNA Immunization of Mice with Drug Resistant Integrases of HIV-1 Clade A Offers Partial Protection against Growth and Metastatic Activity of Integrase-Expressing Adenocarcinoma Cells.
Isaguliants M, Krotova O, Petkov S, Jansons J, Bayurova E, Mezale D, Fridrihsone I, Kilpelainen A, Podschwadt P, Agapkina Y, Smirnova O, Kostic L, Saleem M, Latyshev O, Eliseeva O, Malkova A, Gorodnicheva T, Wahren B, Gordeychuk I, Starodubova E, Latanova A
Microorganisms 2021 Jun 4;9(6)
Microorganisms 2021 Jun 4;9(6)
SARS-CoV-2-specific T cell memory is sustained in COVID-19 convalescent patients for 10 months with successful development of stem cell-like memory T cells.
Jung JH, Rha MS, Sa M, Choi HK, Jeon JH, Seok H, Park DW, Park SH, Jeong HW, Choi WS, Shin EC
Nature communications 2021 Jun 30;12(1):4043
Nature communications 2021 Jun 30;12(1):4043
Neoantigens elicit T cell responses in breast cancer.
Morisaki T, Kubo M, Umebayashi M, Yew PY, Yoshimura S, Park JH, Kiyotani K, Kai M, Yamada M, Oda Y, Nakamura Y, Morisaki T, Nakamura M
Scientific reports 2021 Jun 30;11(1):13590
Scientific reports 2021 Jun 30;11(1):13590
Correlates of Neutralization against SARS-CoV-2 Variants of Concern by Early Pandemic Sera.
Vidal SJ, Collier AY, Yu J, McMahan K, Tostanoski LH, Ventura JD, Aid M, Peter L, Jacob-Dolan C, Anioke T, Chang A, Wan H, Aguayo R, Ngo D, Gerszten RE, Seaman MS, Barouch DH
Journal of virology 2021 Jun 24;95(14):e0040421
Journal of virology 2021 Jun 24;95(14):e0040421
Immunogenicity of COVID-19 mRNA Vaccines in Pregnant and Lactating Women.
Collier AY, McMahan K, Yu J, Tostanoski LH, Aguayo R, Ansel J, Chandrashekar A, Patel S, Apraku Bondzie E, Sellers D, Barrett J, Sanborn O, Wan H, Chang A, Anioke T, Nkolola J, Bradshaw C, Jacob-Dolan C, Feldman J, Gebre M, Borducchi EN, Liu J, Schmidt AG, Suscovich T, Linde C, Alter G, Hacker MR, Barouch DH
JAMA 2021 Jun 15;325(23):2370-2380
JAMA 2021 Jun 15;325(23):2370-2380
Manufacturing NKG2D CAR-T cells with piggyBac transposon vectors and K562 artificial antigen-presenting cells.
Tay JCK, Wang J, Du Z, Ng YY, Li Z, Ren Y, Zhang C, Zhu J, Xu XH, Wang S
Molecular therapy. Methods & clinical development 2021 Jun 11;21:107-120
Molecular therapy. Methods & clinical development 2021 Jun 11;21:107-120
Reduced blood-stage malaria growth and immune correlates in humans following RH5 vaccination.
Minassian AM, Silk SE, Barrett JR, Nielsen CM, Miura K, Diouf A, Loos C, Fallon JK, Michell AR, White MT, Edwards NJ, Poulton ID, Mitton CH, Payne RO, Marks M, Maxwell-Scott H, Querol-Rubiera A, Bisnauthsing K, Batra R, Ogrina T, Brendish NJ, Themistocleous Y, Rawlinson TA, Ellis KJ, Quinkert D, Baker M, Lopez Ramon R, Ramos Lopez F, Barfod L, Folegatti PM, Silman D, Datoo M, Taylor IJ, Jin J, Pulido D, Douglas AD, de Jongh WA, Smith R, Berrie E, Noe AR, Diggs CL, Soisson LA, Ashfield R, Faust SN, Goodman AL, Lawrie AM, Nugent FL, Alter G, Long CA, Draper SJ
Med (New York, N.Y.) 2021 Jun 11;2(6):701-719.e19
Med (New York, N.Y.) 2021 Jun 11;2(6):701-719.e19
Genome-Wide B Cell, CD4(+), and CD8(+) T Cell Epitopes That Are Highly Conserved between Human and Animal Coronaviruses, Identified from SARS-CoV-2 as Targets for Preemptive Pan-Coronavirus Vaccines.
Prakash S, Srivastava R, Coulon PG, Dhanushkodi NR, Chentoufi AA, Tifrea DF, Edwards RA, Figueroa CJ, Schubl SD, Hsieh L, Buchmeier MJ, Bouziane M, Nesburn AB, Kuppermann BD, BenMohamed L
Journal of immunology (Baltimore, Md. : 1950) 2021 Jun 1;206(11):2566-2582
Journal of immunology (Baltimore, Md. : 1950) 2021 Jun 1;206(11):2566-2582
Bi/tri-specific antibodies (HN-Fc-CD16 and HN-Fc-IL-15-CD16) cross-linking natural killer (NK)-CD16 and Newcastle Disease Virus (NDV)-HN, enhanced NK activation for cancer immunotherapy.
Bahrololoumi Shapourabadi M, Momburg F, Roohvand F, Jarahian M, Mohajel N, Arashkia A, Hajari Taheri F, Abbasalipour M, Azadmanesh K
International immunopharmacology 2021 Jul;96:107762
International immunopharmacology 2021 Jul;96:107762
Phase 1 study of safety, tolerability and immunogenicity of the human telomerase (hTERT)-encoded DNA plasmids INO-1400 and INO-1401 with or without IL-12 DNA plasmid INO-9012 in adult patients with solid tumors.
Vonderheide RH, Kraynyak KA, Shields AF, McRee AJ, Johnson JM, Sun W, Chintakuntlawar AV, Pawlicki J, Sylvester AJ, McMullan T, Samuels R, Kim JJ, Weiner D, Boyer JD, Morrow MP, Humeau L, Skolnik JM
Journal for immunotherapy of cancer 2021 Jul;9(7)
Journal for immunotherapy of cancer 2021 Jul;9(7)
Neoantigen vaccination induces clinical and immunologic responses in non-small cell lung cancer patients harboring EGFR mutations.
Li F, Deng L, Jackson KR, Talukder AH, Katailiha AS, Bradley SD, Zou Q, Chen C, Huo C, Chiu Y, Stair M, Feng W, Bagaev A, Kotlov N, Svekolkin V, Ataullakhanov R, Miheecheva N, Frenkel F, Wang Y, Zhang M, Hawke D, Han L, Zhou S, Zhang Y, Wang Z, Decker WK, Sonnemann HM, Roszik J, Forget MA, Davies MA, Bernatchez C, Yee C, Bassett R, Hwu P, Du X, Lizee G
Journal for immunotherapy of cancer 2021 Jul;9(7)
Journal for immunotherapy of cancer 2021 Jul;9(7)
Identification of neoantigen-reactive T lymphocytes in the peripheral blood of a patient with glioblastoma.
Leko V, Cafri G, Yossef R, Paria B, Hill V, Gurusamy D, Zheng Z, Gartner JJ, Prickett TD, Goff SL, Robbins P, Lu YC, Rosenberg SA
Journal for immunotherapy of cancer 2021 Jul;9(7)
Journal for immunotherapy of cancer 2021 Jul;9(7)
Hepatitis E Infection in a Longitudinal Cohort of Hepatitis C Virus and HCV/HIV Coinfected Persons.
Sherman KE, Kottilil S, Rouster SD, Abdel-Hameed EA, Boyce CL, Meeds HL, Terrault N, Shata MT
AIDS research and human retroviruses 2021 Jul;37(7):534-541
AIDS research and human retroviruses 2021 Jul;37(7):534-541
Immune responses to a single dose of the AZD1222/Covishield vaccine in health care workers.
Jeewandara C, Kamaladasa A, Pushpakumara PD, Jayathilaka D, Aberathna IS, Danasekara DRSR, Guruge D, Ranasinghe T, Dayarathna S, Pathmanathan T, Somathilake G, Deshan Madhusanka PA, Ramu ST, Pramanayagam Jayadas TT, Kuruppu H, Wijesinghe A, Thashmi Nimasha HM, Milroy D, Nandasena AA, Nilanka Sanjeewani PKG, Wijayamuni R, Samaraweera S, Schimanski L, Tan TK, Dong T, Ogg GS, Townsend A, Malavige GN
Nature communications 2021 Jul 29;12(1):4617
Nature communications 2021 Jul 29;12(1):4617
Impact of SARS-CoV-2 variants on the total CD4(+) and CD8(+) T cell reactivity in infected or vaccinated individuals.
Tarke A, Sidney J, Methot N, Yu ED, Zhang Y, Dan JM, Goodwin B, Rubiro P, Sutherland A, Wang E, Frazier A, Ramirez SI, Rawlings SA, Smith DM, da Silva Antunes R, Peters B, Scheuermann RH, Weiskopf D, Crotty S, Grifoni A, Sette A
Cell reports. Medicine 2021 Jul 20;2(7):100355
Cell reports. Medicine 2021 Jul 20;2(7):100355
Young infants exhibit robust functional antibody responses and restrained IFN-γ production to SARS-CoV-2.
Goenka A, Halliday A, Gregorova M, Milodowski E, Thomas A, Williamson MK, Baum H, Oliver E, Long AE, Knezevic L, Williams AJK, Lampasona V, Piemonti L, Gupta K, Di Bartolo N, Berger I, Toye AM, Vipond B, Muir P, Bernatoniene J, Bailey M, Gillespie KM, Davidson AD, Wooldridge L, Rivino L, Finn A
Cell reports. Medicine 2021 Jul 20;2(7):100327
Cell reports. Medicine 2021 Jul 20;2(7):100327
Cell-Associated HIV Cross-Presentation by Plasmacytoid Dendritic Cells Is Potentiated by Noncognate CD8(+) T Cell Preactivation.
Isnard S, Hatton EX, Iannetta M, Guillerme JB, Hosmalin A
Journal of immunology (Baltimore, Md. : 1950) 2021 Jul 1;207(1):15-22
Journal of immunology (Baltimore, Md. : 1950) 2021 Jul 1;207(1):15-22
Safety and immunogenicity of INO-4800 DNA vaccine against SARS-CoV-2: A preliminary report of an open-label, Phase 1 clinical trial.
Tebas P, Yang S, Boyer JD, Reuschel EL, Patel A, Christensen-Quick A, Andrade VM, Morrow MP, Kraynyak K, Agnes J, Purwar M, Sylvester A, Pawlicki J, Gillespie E, Maricic I, Zaidi FI, Kim KY, Dia Y, Frase D, Pezzoli P, Schultheis K, Smith TRF, Ramos SJ, McMullan T, Buttigieg K, Carroll MW, Ervin J, Diehl MC, Blackwood E, Mammen MP, Lee J, Dallas MJ, Brown AS, Shea JE, Kim JJ, Weiner DB, Broderick KE, Humeau LM
EClinicalMedicine 2021 Jan;31:100689
EClinicalMedicine 2021 Jan;31:100689
Cellular Immunity in COVID-19 Convalescents with PCR-Confirmed Infection but with Undetectable SARS-CoV-2-Specific IgG.
Schwarzkopf S, Krawczyk A, Knop D, Klump H, Heinold A, Heinemann FM, Thümmler L, Temme C, Breyer M, Witzke O, Dittmer U, Lenz V, Horn PA, Lindemann M
Emerging infectious diseases 2021 Jan;27(1)
Emerging infectious diseases 2021 Jan;27(1)
Identification of new cytokine combinations for antigen-specific T-cell therapy products via a high-throughput multi-parameter assay.
Lazarski CA, Datar AA, Reynolds EK, Keller MD, Bollard CM, Hanley PJ
Cytotherapy 2021 Jan;23(1):65-76
Cytotherapy 2021 Jan;23(1):65-76
SARS-CoV-2-derived peptides define heterologous and COVID-19-induced T cell recognition.
Nelde A, Bilich T, Heitmann JS, Maringer Y, Salih HR, Roerden M, Lübke M, Bauer J, Rieth J, Wacker M, Peter A, Hörber S, Traenkle B, Kaiser PD, Rothbauer U, Becker M, Junker D, Krause G, Strengert M, Schneiderhan-Marra N, Templin MF, Joos TO, Kowalewski DJ, Stos-Zweifel V, Fehr M, Rabsteyn A, Mirakaj V, Karbach J, Jäger E, Graf M, Gruber LC, Rachfalski D, Preuß B, Hagelstein I, Märklin M, Bakchoul T, Gouttefangeas C, Kohlbacher O, Klein R, Stevanović S, Rammensee HG, Walz JS
Nature immunology 2021 Jan;22(1):74-85
Nature immunology 2021 Jan;22(1):74-85
Safety and immunogenicity of an inactivated SARS-CoV-2 vaccine, BBIBP-CorV: a randomised, double-blind, placebo-controlled, phase 1/2 trial.
Xia S, Zhang Y, Wang Y, Wang H, Yang Y, Gao GF, Tan W, Wu G, Xu M, Lou Z, Huang W, Xu W, Huang B, Wang H, Wang W, Zhang W, Li N, Xie Z, Ding L, You W, Zhao Y, Yang X, Liu Y, Wang Q, Huang L, Yang Y, Xu G, Luo B, Wang W, Liu P, Guo W, Yang X
The Lancet. Infectious diseases 2021 Jan;21(1):39-51
The Lancet. Infectious diseases 2021 Jan;21(1):39-51
Simultaneous testing of immunological sensitization to multiple antigens in sarcoidosis reveals an association with inorganic antigens specifically related to a fibrotic phenotype.
Beijer E, Kraaijvanger R, Roodenburg C, Grutters JC, Meek B, Veltkamp M
Clinical and experimental immunology 2021 Jan;203(1):115-124
Clinical and experimental immunology 2021 Jan;203(1):115-124
Restoration of T-cell Effector Function, Depletion of Tregs, and Direct Killing of Tumor Cells: The Multiple Mechanisms of Action of a-TIGIT Antagonist Antibodies.
Preillon J, Cuende J, Rabolli V, Garnero L, Mercier M, Wald N, Pappalardo A, Denies S, Jamart D, Michaux AC, Pirson R, Pitard V, Bagot M, Prasad S, Houthuys E, Brouwer M, Marillier R, Lambolez F, Marchante JR, Nyawouame F, Carter MJ, Baron-Bodo V, Marie-Cardine A, Cragg M, Déchanet-Merville J, Driessens G, Hoofd C
Molecular cancer therapeutics 2021 Jan;20(1):121-131
Molecular cancer therapeutics 2021 Jan;20(1):121-131
Dissemination of Mycobacterium tuberculosis is associated to a SIGLEC1 null variant that limits antigen exchange via trafficking extracellular vesicles.
Benet S, Gálvez C, Drobniewski F, Kontsevaya I, Arias L, Monguió-Tortajada M, Erkizia I, Urrea V, Ong RY, Luquin M, Dupont M, Chojnacki J, Dalmau J, Cardona P, Neyrolles O, Lugo-Villarino G, Vérollet C, Julián E, Furrer H, Günthard HF, Crocker PR, Tapia G, Borràs FE, Fellay J, McLaren PJ, Telenti A, Cardona PJ, Clotet B, Vilaplana C, Martinez-Picado J, Izquierdo-Useros N
Journal of extracellular vesicles 2021 Jan;10(3):e12046
Journal of extracellular vesicles 2021 Jan;10(3):e12046
A biomimetic assay platform for the interrogation of antigen-dependent anti-tumor T-cell function.
To J, Quackenbush D, Rowell E, Li L, Reed C, Lo F, Horman SR
Communications biology 2021 Jan 8;4(1):56
Communications biology 2021 Jan 8;4(1):56
Human skin is colonized by T cells that recognize CD1a independently of lipid.
Cotton RN, Cheng TY, Wegrecki M, Le Nours J, Orgill DP, Pomahac B, Talbot SG, Willis RA, Altman JD, de Jong A, Ogg G, Van Rhijn I, Rossjohn J, Clark RA, Moody DB
The Journal of clinical investigation 2021 Jan 4;131(1)
The Journal of clinical investigation 2021 Jan 4;131(1)
Evaluation of the Expression of CCR5 and CX3CR1 Receptors and Correlation with the Functionality of T Cells in Women infected with ZIKV during Pregnancy.
Familiar-Macedo D, Amancio Paiva I, Badolato-Corrêa da Silva J, de Carvalho FR, Dias HG, Pauvolid-Corrêa A, Dos Santos CF, Gandini M, Silva AA, Baeta Cavalcanti SM, Artimos de Oliveira S, Artimos de Oliveira Vianna R, Leal de Azeredo E, Grifoni A, Sette A, Weiskopf D, Araújo Cardoso CA, de-Oliveira-Pinto LM
Viruses 2021 Jan 28;13(2)
Viruses 2021 Jan 28;13(2)
Constitutively Activated DAP12 Induces Functional Anti-Tumor Activation and Maturation of Human Monocyte-Derived DC.
Dalton R, Calescibetta A, Zhou JM, Maurin M, Ward G, Trinh TL, Tu N, Gilvary D, Chen X, Cheng P, Kostenko E, Wei S, Wright KL, Eksioglu EA
International journal of molecular sciences 2021 Jan 27;22(3)
International journal of molecular sciences 2021 Jan 27;22(3)
Characterization of ascites- and tumor-infiltrating γδ T cells reveals distinct repertoires and a beneficial role in ovarian cancer.
Foord E, Arruda LCM, Gaballa A, Klynning C, Uhlin M
Science translational medicine 2021 Jan 20;13(577)
Science translational medicine 2021 Jan 20;13(577)
The TCR repertoire of α-synuclein-specific T cells in Parkinson's disease is surprisingly diverse.
Singhania A, Pham J, Dhanwani R, Frazier A, Rezende Dutra J, Marder KS, Phillips E, Mallal S, Amara AW, Standaert DG, Sulzer D, Peters B, Sette A, Lindestam Arlehamn CS
Scientific reports 2021 Jan 11;11(1):302
Scientific reports 2021 Jan 11;11(1):302
Safety, tolerability, and immunogenicity of an inactivated SARS-CoV-2 vaccine in healthy adults aged 18-59 years: a randomised, double-blind, placebo-controlled, phase 1/2 clinical trial.
Zhang Y, Zeng G, Pan H, Li C, Hu Y, Chu K, Han W, Chen Z, Tang R, Yin W, Chen X, Hu Y, Liu X, Jiang C, Li J, Yang M, Song Y, Wang X, Gao Q, Zhu F
The Lancet. Infectious diseases 2021 Feb;21(2):181-192
The Lancet. Infectious diseases 2021 Feb;21(2):181-192
Cytotoxic T cells isolated from healthy donors and cancer patients kill TGFβ-expressing cancer cells in a TGFβ-dependent manner.
Holmström MO, Mortensen REJ, Pavlidis AM, Martinenaite E, Weis-Banke SE, Aaboe-Jørgensen M, Bendtsen SK, Met Ö, Pedersen AW, Donia M, Svane IM, Andersen MH
Cellular & molecular immunology 2021 Feb;18(2):415-426
Cellular & molecular immunology 2021 Feb;18(2):415-426
In vivo dynamics and adaptation of HTLV-1-infected clones under different clinical conditions.
Izaki M, Yasunaga JI, Nosaka K, Sugata K, Utsunomiya H, Suehiro Y, Shichijo T, Yamada A, Sugawara Y, Hibi T, Inomata Y, Akari H, Melamed A, Bangham C, Matsuoka M
PLoS pathogens 2021 Feb;17(2):e1009271
PLoS pathogens 2021 Feb;17(2):e1009271
Identification of the association between HBcAg-specific T cell and viral control in chronic HBV infection using a cultured ELISPOT assay.
Chen C, Jiang X, Liu X, Guo L, Wang W, Gu S, Wen C, Yi X, Tang L, Li Y
Journal of leukocyte biology 2021 Feb;109(2):455-465
Journal of leukocyte biology 2021 Feb;109(2):455-465
Early induction of functional SARS-CoV-2-specific T cells associates with rapid viral clearance and mild disease in COVID-19 patients.
Tan AT, Linster M, Tan CW, Le Bert N, Chia WN, Kunasegaran K, Zhuang Y, Tham CYL, Chia A, Smith GJD, Young B, Kalimuddin S, Low JGH, Lye D, Wang LF, Bertoletti A
Cell reports 2021 Feb 9;34(6):108728
Cell reports 2021 Feb 9;34(6):108728
HIV-specific T cell responses reflect substantive in vivo interactions with antigen despite long-term therapy.
Stevenson EM, Ward AR, Truong R, Thomas AS, Huang SH, Dilling TR, Terry S, Bui JK, Mota TM, Danesh A, Lee GQ, Gramatica A, Khadka P, Alberto WDC, Gandhi RT, McMahon DK, Lalama CM, Bosch RJ, Macatangay B, Cyktor JC, Eron JJ, Mellors JW, Jones RB, AIDS Clinical Trials Group A5321 Team
JCI insight 2021 Feb 8;6(3)
JCI insight 2021 Feb 8;6(3)
First-in-Human Phase I Clinical Trial of an SFV-Based RNA Replicon Cancer Vaccine against HPV-Induced Cancers.
Komdeur FL, Singh A, van de Wall S, Meulenberg JJM, Boerma A, Hoogeboom BN, Paijens ST, Oyarce C, de Bruyn M, Schuuring E, Regts J, Marra R, Werner N, Sluis J, van der Zee AGJ, Wilschut JC, Allersma DP, van Zanten CJ, Kosterink JGW, Jorritsma-Smit A, Yigit R, Nijman HW, Daemen T
Molecular therapy : the journal of the American Society of Gene Therapy 2021 Feb 3;29(2):611-625
Molecular therapy : the journal of the American Society of Gene Therapy 2021 Feb 3;29(2):611-625
Ageing of Immune System and Response to a Live-Attenuated Herpes Zoster Vaccine in Lung Transplant Candidates.
Wang L, Verschuuren EAM, Paap D, Rondaan C, Raveling-Eelsing E, Liu S, Westra J, Bos NA
Vaccines 2021 Feb 28;9(3)
Vaccines 2021 Feb 28;9(3)
Characterization of the Class I MHC Peptidome Resulting From DNCB Exposure of HaCaT Cells.
Bailey A, Nicholas B, Darley R, Parkinson E, Teo Y, Aleksic M, Maxwell G, Elliott T, Ardern-Jones M, Skipp P
Toxicological sciences : an official journal of the Society of Toxicology 2021 Feb 26;180(1):136-147
Toxicological sciences : an official journal of the Society of Toxicology 2021 Feb 26;180(1):136-147
Characterization of a Unique γδ T-Cell Subset as a Specific Marker of Cytomegalovirus Infection Severity.
Kaminski H, Ménard C, El Hayani B, Adjibabi AN, Marsères G, Courant M, Zouine A, Pitard V, Garrigue I, Burrel S, Moreau JF, Couzi L, Visentin J, Merville P, Déchanet-Merville J
The Journal of infectious diseases 2021 Feb 24;223(4):655-666
The Journal of infectious diseases 2021 Feb 24;223(4):655-666
Vaccination against PD-L1 with IO103 a Novel Immune Modulatory Vaccine in Basal Cell Carcinoma: A Phase IIa Study.
Jørgensen NG, Kaae J, Grauslund JH, Met Ö, Nielsen SL, Pedersen AW, Svane IM, Ehrnrooth E, Andersen MH, Zachariae C, Skov L
Cancers 2021 Feb 22;13(4)
Cancers 2021 Feb 22;13(4)
Prediction of neo-epitope immunogenicity reveals TCR recognition determinants and provides insight into immunoediting.
Schmidt J, Smith AR, Magnin M, Racle J, Devlin JR, Bobisse S, Cesbron J, Bonnet V, Carmona SJ, Huber F, Ciriello G, Speiser DE, Bassani-Sternberg M, Coukos G, Baker BM, Harari A, Gfeller D
Cell reports. Medicine 2021 Feb 16;2(2):100194
Cell reports. Medicine 2021 Feb 16;2(2):100194
Neoadjuvant anti-OX40 (MEDI6469) therapy in patients with head and neck squamous cell carcinoma activates and expands antigen-specific tumor-infiltrating T cells.
Duhen R, Ballesteros-Merino C, Frye AK, Tran E, Rajamanickam V, Chang SC, Koguchi Y, Bifulco CB, Bernard B, Leidner RS, Curti BD, Fox BA, Urba WJ, Bell RB, Weinberg AD
Nature communications 2021 Feb 16;12(1):1047
Nature communications 2021 Feb 16;12(1):1047
Characterization of humoral and SARS-CoV-2 specific T cell responses in people living with HIV.
Alrubayyi A, Gea-Mallorquí E, Touizer E, Hameiri-Bowen D, Kopycinski J, Charlton B, Fisher-Pearson N, Muir L, Rosa A, Roustan C, Earl C, Cherepanov P, Pellegrino P, Waters L, Burns F, Kinloch S, Dong T, Dorrell L, Rowland-Jones S, McCoy LE, Peppa D
bioRxiv : the preprint server for biology 2021 Feb 16;
bioRxiv : the preprint server for biology 2021 Feb 16;
Cellular and humoral immune response after mRNA-1273 SARS-CoV-2 vaccine in liver and heart transplant recipients.
Herrera S, Colmenero J, Pascal M, Escobedo M, Castel MA, Sole-González E, Palou E, Egri N, Ruiz P, Mosquera M, Moreno A, Juan M, Vilella A, Soriano A, Farrero M, Bodro M
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2021 Dec;21(12):3971-3979
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2021 Dec;21(12):3971-3979
Adaptive immunity and neutralizing antibodies against SARS-CoV-2 variants of concern following vaccination in patients with cancer: The CAPTURE study.
Fendler A, Shepherd STC, Au L, Wilkinson KA, Wu M, Byrne F, Cerrone M, Schmitt AM, Joharatnam-Hogan N, Shum B, Tippu Z, Rzeniewicz K, Boos LA, Harvey R, Carlyle E, Edmonds K, Del Rosario L, Sarker S, Lingard K, Mangwende M, Holt L, Ahmod H, Korteweg J, Foley T, Bazin J, Gordon W, Barber T, Emslie-Henry A, Xie W, Gerard CL, Deng D, Wall EC, Agua-Doce A, Namjou S, Caidan S, Gavrielides M, MacRae JI, Kelly G, Peat K, Kelly D, Murra A, Kelly K, O'Flaherty M, Dowdie L, Ash N, Gronthoud F, Shea RL, Gardner G, Murray D, Kinnaird F, Cui W, Pascual J, Rodney S, Mencel J, Curtis O, Stephenson C, Robinson A, Oza B, Farag S, Leslie I, Rogiers A, Iyengar S, Ethell M, Messiou C, Cunningham D, Chau I, Starling N, Turner N, Welsh L, van As N, Jones RL, Droney J, Banerjee S, Tatham KC, O'Brien M, Harrington K, Bhide S, Okines A, Reid A, Young K, Furness AJS, Pickering L, Swanton C, Crick COVID19 consortium, Gandhi S, Gamblin S, Bauer DL, Kassiotis G, Kumar S, Yousaf N, Jhanji S, Nicholson E, Howell M, Walker S, Wilkinson RJ, Larkin J, Turajlic S
Nature cancer 2021 Dec;2:1321-1337
Nature cancer 2021 Dec;2:1321-1337
Acute exercise increases immune responses to SARS CoV-2 in a previously infected man.
Baker FL, Smith KA, Zúñiga TM, Batatinha H, Niemiro GM, Pedlar CR, Burgess SC, Katsanis E, Simpson RJ
Brain, behavior, & immunity - health 2021 Dec;18:100343
Brain, behavior, & immunity - health 2021 Dec;18:100343
Cytotoxic CD4+ T-cells specific for EBV capsid antigen BORF1 are maintained in long-term latently infected healthy donors.
Dowell AC, Haigh TA, Ryan GB, Turner JE, Long HM, Taylor GS
PLoS pathogens 2021 Dec;17(12):e1010137
PLoS pathogens 2021 Dec;17(12):e1010137
Hydroxychloroquine inhibits the mitochondrial antioxidant system in activated T cells.
Kim ML, Hardy MY, Edgington-Mitchell LE, Ramarathinam SH, Chung SZ, Russell AK, Currie I, Sleebs BE, Purcell AW, Tye-Din JA, Wicks IP
iScience 2021 Dec 17;24(12):103509
iScience 2021 Dec 17;24(12):103509
Kaposi's sarcoma-associated herpesvirus T cell responses in HIV seronegative individuals from rural Uganda.
Nalwoga A, Roshan R, Moore K, Marshall V, Miley W, Labo N, Nakibuule M, Cose S, Rochford R, Newton R, Whitby D
Nature communications 2021 Dec 16;12(1):7323
Nature communications 2021 Dec 16;12(1):7323
Platelet PD-L1 reflects collective intratumoral PD-L1 expression and predicts immunotherapy response in non-small cell lung cancer.
Hinterleitner C, Strähle J, Malenke E, Hinterleitner M, Henning M, Seehawer M, Bilich T, Heitmann J, Lutz M, Mattern S, Scheuermann S, Horger M, Maurer S, Walz J, Fend F, Handgretinger R, Seitz C, Weigelin B, Singer S, Salih H, Borst O, Kopp HG, Zender L
Nature communications 2021 Dec 1;12(1):7005
Nature communications 2021 Dec 1;12(1):7005
Phase Ib study of patients with metastatic castrate-resistant prostate cancer treated with different sequencing regimens of atezolizumab and sipuleucel-T.
Dorff T, Hirasawa Y, Acoba J, Pagano I, Tamura D, Pal S, Zhang M, Waitz R, Dhal A, Haynes W, Shon J, Scholz M, Furuya H, Chan OTM, Huang J, Rosser C
Journal for immunotherapy of cancer 2021 Aug;9(8)
Journal for immunotherapy of cancer 2021 Aug;9(8)
IL-7 expands lymphocyte populations and enhances immune responses to sipuleucel-T in patients with metastatic castration-resistant prostate cancer (mCRPC).
Pachynski RK, Morishima C, Szmulewitz R, Harshman L, Appleman L, Monk P, Bitting RL, Kucuk O, Millard F, Seigne JD, Fling SP, Maecker HT, Duault C, Ramchurren N, Hess B, D'Amico L, Lacroix A, Kaiser JC, Morre M, Grégoire A, Cheever M, Yu EY, Fong L
Journal for immunotherapy of cancer 2021 Aug;9(8)
Journal for immunotherapy of cancer 2021 Aug;9(8)
Safety and immunogenicity of the ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 in HIV infection: a single-arm substudy of a phase 2/3 clinical trial.
Frater J, Ewer KJ, Ogbe A, Pace M, Adele S, Adland E, Alagaratnam J, Aley PK, Ali M, Ansari MA, Bara A, Bittaye M, Broadhead S, Brown A, Brown H, Cappuccini F, Cooney E, Dejnirattisai W, Dold C, Fairhead C, Fok H, Folegatti PM, Fowler J, Gibbs C, Goodman AL, Jenkin D, Jones M, Makinson R, Marchevsky NG, Mujadidi YF, Nguyen H, Parolini L, Petersen C, Plested E, Pollock KM, Ramasamy MN, Rhead S, Robinson H, Robinson N, Rongkard P, Ryan F, Serrano S, Tipoe T, Voysey M, Waters A, Zacharopoulou P, Barnes E, Dunachie S, Goulder P, Klenerman P, Screaton GR, Winston A, Hill AVS, Gilbert SC, Pollard AJ, Fidler S, Fox J, Lambe T, Oxford COVID Vaccine Trial Group
The lancet. HIV 2021 Aug;8(8):e474-e485
The lancet. HIV 2021 Aug;8(8):e474-e485
ELISpot assay as a diagnostic tool in drug hypersensitivity reactions.
Porebski G, Piotrowicz-Wojcik K, Spiewak R
Journal of immunological methods 2021 Aug;495:113062
Journal of immunological methods 2021 Aug;495:113062
Alternative Evaluation of an ELISPOT Assay Using Cytokine Activity as a Novel Parameter.
Maeda C, Iizuka A, Miyata H, Kondou R, Ashizawa T, Kanematsu A, Watanabe K, Deguchi S, Mitsuya K, Hayashi N, Abe Y, Yamaguchi K, Akiyama Y
Anticancer research 2021 Aug;41(8):3825-3831
Anticancer research 2021 Aug;41(8):3825-3831
Tumor-infiltrating lymphocyte treatment for anti-PD-1-resistant metastatic lung cancer: a phase 1 trial.
Creelan BC, Wang C, Teer JK, Toloza EM, Yao J, Kim S, Landin AM, Mullinax JE, Saller JJ, Saltos AN, Noyes DR, Montoya LB, Curry W, Pilon-Thomas SA, Chiappori AA, Tanvetyanon T, Kaye FJ, Thompson ZJ, Yoder SJ, Fang B, Koomen JM, Sarnaik AA, Chen DT, Conejo-Garcia JR, Haura EB, Antonia SJ
Nature medicine 2021 Aug;27(8):1410-1418
Nature medicine 2021 Aug;27(8):1410-1418
Cytokine release syndrome in a patient with colorectal cancer after vaccination with BNT162b2.
Au L, Fendler A, Shepherd STC, Rzeniewicz K, Cerrone M, Byrne F, Carlyle E, Edmonds K, Del Rosario L, Shon J, Haynes WA, Ward B, Shum B, Gordon W, Gerard CL, Xie W, Joharatnam-Hogan N, Young K, Pickering L, Furness AJS, Larkin J, Harvey R, Kassiotis G, Gandhi S, Crick COVID-19 Consortium, Swanton C, Fribbens C, Wilkinson KA, Wilkinson RJ, Lau DK, Banerjee S, Starling N, Chau I, CAPTURE Consortium, Turajlic S
Nature medicine 2021 Aug;27(8):1362-1366
Nature medicine 2021 Aug;27(8):1362-1366
Preexisting and Post-COVID-19 Immune Responses to SARS-CoV-2 in Patients with Cancer.
Bilich T, Roerden M, Maringer Y, Nelde A, Heitmann JS, Dubbelaar ML, Peter A, Hörber S, Bauer J, Rieth J, Wacker M, Berner F, Flatz L, Held S, Brossart P, Märklin M, Wagner P, Erne E, Klein R, Rammensee HG, Salih HR, Walz JS
Cancer discovery 2021 Aug;11(8):1982-1995
Cancer discovery 2021 Aug;11(8):1982-1995
Deciphering Adverse Drug Reactions: In Vitro Priming and Characterization of Vancomycin-Specific T Cells From Healthy Donors Expressing HLA-A*32:01.
Ogese MO, Lister A, Gardner J, Meng X, Alfirevic A, Pirmohamed M, Park BK, Naisbitt DJ
Toxicological sciences : an official journal of the Society of Toxicology 2021 Aug 30;183(1):139-153
Toxicological sciences : an official journal of the Society of Toxicology 2021 Aug 30;183(1):139-153
The RECOVAC IR study: the immune response and safety of the mRNA-1273 COVID-19 vaccine in patients with chronic kidney disease, on dialysis or living with a kidney transplant.
Kho MML, Reinders MEJ, Baan CC, van Baarle D, Bemelman FJ, Diavatopoulos DA, Gansevoort RT, van der Klis FRM, Koopmans MPG, Messchendorp AL, van der Molen RG, Remmerswaal EBM, Rots N, Vart P, de Vries RD, Hilbrands LB, Sanders JF, RECOVAC Collaborators
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2021 Aug 27;36(9):1761-1764
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2021 Aug 27;36(9):1761-1764
Development of a novel ZIKV vaccine comprised of immunodominant CD4+ and CD8+ T cell epitopes identified through comprehensive epitope mapping in Zika virus infected mice.
Sun J, Zheng Z, Li M, Liu Z, Su X, Jin X
Vaccine 2021 Aug 23;39(36):5173-5186
Vaccine 2021 Aug 23;39(36):5173-5186
A high-affinity human TCR-like antibody detects celiac disease gluten peptide-MHC complexes and inhibits T cell activation.
Frick R, Høydahl LS, Petersen J, du Pré MF, Kumari S, Berntsen G, Dewan AE, Jeliazkov JR, Gunnarsen KS, Frigstad T, Vik ES, Llerena C, Lundin KEA, Yaqub S, Jahnsen J, Gray JJ, Rossjohn J, Sollid LM, Sandlie I, Løset GÅ
Science immunology 2021 Aug 20;6(62)
Science immunology 2021 Aug 20;6(62)
Two doses of SARS-CoV-2 vaccination induce robust immune responses to emerging SARS-CoV-2 variants of concern.
Skelly DT, Harding AC, Gilbert-Jaramillo J, Knight ML, Longet S, Brown A, Adele S, Adland E, Brown H, Medawar Laboratory Team, Tipton T, Stafford L, Mentzer AJ, Johnson SA, Amini A, OPTIC (Oxford Protective T cell Immunology for COVID-19) Clinical Group, Tan TK, Schimanski L, Huang KA, Rijal P, PITCH (Protective Immunity T cells in Health Care Worker) Study Group, C-MORE/PHOSP-C Group, Frater J, Goulder P, Conlon CP, Jeffery K, Dold C, Pollard AJ, Sigal A, de Oliveira T, Townsend AR, Klenerman P, Dunachie SJ, Barnes E, Carroll MW, James WS
Nature communications 2021 Aug 17;12(1):5061
Nature communications 2021 Aug 17;12(1):5061
Comparison of SARS-CoV-2- and HCoV-Specific T Cell Response Using IFN-γ ELISpot.
Thümmler L, Schwarzkopf S, Knop D, Ross JA, Berg V, Horn PA, Lindemann M
Diagnostics (Basel, Switzerland) 2021 Aug 10;11(8)
Diagnostics (Basel, Switzerland) 2021 Aug 10;11(8)
A vaccine targeting mutant IDH1 in newly diagnosed glioma.
Platten M, Bunse L, Wick A, Bunse T, Le Cornet L, Harting I, Sahm F, Sanghvi K, Tan CL, Poschke I, Green E, Justesen S, Behrens GA, Breckwoldt MO, Freitag A, Rother LM, Schmitt A, Schnell O, Hense J, Misch M, Krex D, Stevanovic S, Tabatabai G, Steinbach JP, Bendszus M, von Deimling A, Schmitt M, Wick W
Nature 2021 Apr;592(7854):463-468
Nature 2021 Apr;592(7854):463-468
Comprehensive epitope mapping using polyclonally expanded human CD8 T cells and a two-step ELISpot assay for testing large peptide libraries.
Michelo CM, Dalel JA, Hayes P, Fernandez N, Fiore-Gartland A, Kilembe W, Tang J, Streatfield C, Gilmour J, Hunter E
Journal of immunological methods 2021 Apr;491:112970
Journal of immunological methods 2021 Apr;491:112970
Illuminating the in vitro effects of Epstein-Barr virus and vitamin D on immune response in multiple sclerosis patients.
Teymoori-Rad M, Sahraian MA, Mokhtariazad T, Nejati A, Mozdabadi RSK, Amiri MM, Shokri F, Marashi SM
Journal of neurovirology 2021 Apr;27(2):260-271
Journal of neurovirology 2021 Apr;27(2):260-271
Longitudinal antibody and T cell responses in Ebola virus disease survivors and contacts: an observational cohort study.
Thom R, Tipton T, Strecker T, Hall Y, Akoi Bore J, Maes P, Raymond Koundouno F, Fehling SK, Krähling V, Steeds K, Varghese A, Bailey G, Matheson M, Kouyate S, Coné M, Moussa Keita B, Kouyate S, Richard Ablam A, Laenen L, Vergote V, Guiver M, Timothy J, Atkinson B, Ottowell L, Richards KS, Bosworth A, Longet S, Mellors J, Pannetier D, Duraffour S, Muñoz-Fontela C, Sow O, Koivogui L, Newman E, Becker S, Sprecher A, Raoul H, Hiscox J, Henao-Restrepo AM, Sakoba K, Magassouba N, Günther S, Kader Konde M, Carroll MW
The Lancet. Infectious diseases 2021 Apr;21(4):507-516
The Lancet. Infectious diseases 2021 Apr;21(4):507-516
Phase I studies of peptide vaccine cocktails derived from GPC3, WDRPUH and NEIL3 for advanced hepatocellular carcinoma.
Ikeda M, Okusaka T, Ohno I, Mitsunaga S, Kondo S, Ueno H, Morizane C, Gemmoto K, Suna H, Ushida Y, Furuse J
Immunotherapy 2021 Apr;13(5):371-385
Immunotherapy 2021 Apr;13(5):371-385
Prognostic significance of interleukin-17A-producing colorectal tumour antigen-specific T cells.
Thomson A, Bento DFC, Scurr MJ, Smart K, Somerville MS, Keita ÅV, Gallimore A, Godkin A
British journal of cancer 2021 Apr;124(9):1552-1555
British journal of cancer 2021 Apr;124(9):1552-1555
T cell assays differentiate clinical and subclinical SARS-CoV-2 infections from cross-reactive antiviral responses.
Ogbe A, Kronsteiner B, Skelly DT, Pace M, Brown A, Adland E, Adair K, Akhter HD, Ali M, Ali SE, Angyal A, Ansari MA, Arancibia-Cárcamo CV, Brown H, Chinnakannan S, Conlon C, de Lara C, de Silva T, Dold C, Dong T, Donnison T, Eyre D, Flaxman A, Fletcher H, Gardner J, Grist JT, Hackstein CP, Jaruthamsophon K, Jeffery K, Lambe T, Lee L, Li W, Lim N, Matthews PC, Mentzer AJ, Moore SC, Naisbitt DJ, Ogese M, Ogg G, Openshaw P, Pirmohamed M, Pollard AJ, Ramamurthy N, Rongkard P, Rowland-Jones S, Sampson O, Screaton G, Sette A, Stafford L, Thompson C, Thomson PJ, Thwaites R, Vieira V, Weiskopf D, Zacharopoulou P, Oxford Immunology Network Covid-19 Response T Cell Consortium, Oxford Protective T Cell Immunology for COVID-19 (OPTIC) Clinical Team, Turtle L, Klenerman P, Goulder P, Frater J, Barnes E, Dunachie S
Nature communications 2021 Apr 6;12(1):2055
Nature communications 2021 Apr 6;12(1):2055
T cell and antibody kinetics delineate SARS-CoV-2 peptides mediating long-term immune responses in COVID-19 convalescent individuals.
Bilich T, Nelde A, Heitmann JS, Maringer Y, Roerden M, Bauer J, Rieth J, Wacker M, Peter A, Hörber S, Rachfalski D, Märklin M, Stevanović S, Rammensee HG, Salih HR, Walz JS
Science translational medicine 2021 Apr 21;13(590)
Science translational medicine 2021 Apr 21;13(590)
Optimized polyepitope neoantigen DNA vaccines elicit neoantigen-specific immune responses in preclinical models and in clinical translation.
Li L, Zhang X, Wang X, Kim SW, Herndon JM, Becker-Hapak MK, Carreno BM, Myers NB, Sturmoski MA, McLellan MD, Miller CA, Johanns TM, Tan BR, Dunn GP, Fleming TP, Hansen TH, Goedegebuure SP, Gillanders WE
Genome medicine 2021 Apr 21;13(1):56
Genome medicine 2021 Apr 21;13(1):56
Atypical acute myeloid leukemia-specific transcripts generate shared and immunogenic MHC class-I-associated epitopes.
Ehx G, Larouche JD, Durette C, Laverdure JP, Hesnard L, Vincent K, Hardy MP, Thériault C, Rulleau C, Lanoix J, Bonneil E, Feghaly A, Apavaloaei A, Noronha N, Laumont CM, Delisle JS, Vago L, Hébert J, Sauvageau G, Lemieux S, Thibault P, Perreault C
Immunity 2021 Apr 13;54(4):737-752.e10
Immunity 2021 Apr 13;54(4):737-752.e10
Noncytotoxic Inhibition of the Immunoproteasome Regulates Human Immune Cells In Vitro and Suppresses Cutaneous Inflammation in the Mouse.
Ah Kioon MD, Pierides M, Pannellini T, Lin G, Nathan CF, Barrat FJ
Journal of immunology (Baltimore, Md. : 1950) 2021 Apr 1;206(7):1631-1641
Journal of immunology (Baltimore, Md. : 1950) 2021 Apr 1;206(7):1631-1641
Rift Valley fever virus vaccination induces long-lived, antigen-specific human T cell responses.
Harmon JR, Barbeau DJ, Nichol ST, Spiropoulou CF, McElroy AK
NPJ vaccines 2020;5(1):17
NPJ vaccines 2020;5(1):17
Immunization with full-length Plasmodium falciparum merozoite surface protein 1 is safe and elicits functional cytophilic antibodies in a randomized first-in-human trial.
Blank A, Fürle K, Jäschke A, Mikus G, Lehmann M, Hüsing J, Heiss K, Giese T, Carter D, Böhnlein E, Lanzer M, Haefeli WE, Bujard H
NPJ vaccines 2020;5(1):10
NPJ vaccines 2020;5(1):10
Optimising T cell (re)boosting strategies for adenoviral and modified vaccinia Ankara vaccine regimens in humans.
Capone S, Brown A, Hartnell F, Sorbo MD, Traboni C, Vassilev V, Colloca S, Nicosia A, Cortese R, Folgori A, Klenerman P, Barnes E, Swadling L
NPJ vaccines 2020;5:94
NPJ vaccines 2020;5:94
Profound Functional Suppression of Tumor-Infiltrating T-Cells in Ovarian Cancer Patients Can Be Reversed Using PD-1-Blocking Antibodies or DARPin® Proteins.
Foord E, Klynning C, Schoutrop E, Förster JM, Krieg J, Mörtberg A, Müller MR, Herzog C, Schiegg D, Villemagne D, Fiedler U, Snell D, Kebble B, Mattsson J, Levitsky V, Uhlin M
Journal of immunology research 2020;2020:7375947
Journal of immunology research 2020;2020:7375947
IMRAS-A clinical trial of mosquito-bite immunization with live, radiation-attenuated P. falciparum sporozoites: Impact of immunization parameters on protective efficacy and generation of a repository of immunologic reagents.
Hickey B, Teneza-Mora N, Lumsden J, Reyes S, Sedegah M, Garver L, Hollingdale MR, Banania JG, Ganeshan H, Dowler M, Reyes A, Tamminga C, Singer A, Simmons A, Belmonte M, Belmonte A, Huang J, Inoue S, Velasco R, Abot S, Vasquez CS, Guzman I, Wong M, Twomey P, Wojnarski M, Moon J, Alcorta Y, Maiolatesi S, Spring M, Davidson S, Chaudhury S, Villasante E, Richie TL, Epstein JE
PloS one 2020;15(6):e0233840
PloS one 2020;15(6):e0233840
Peptide Vaccination Against PD-L1 With IO103 a Novel Immune Modulatory Vaccine in Multiple Myeloma: A Phase I First-in-Human Trial.
Jørgensen NG, Klausen U, Grauslund JH, Helleberg C, Aagaard TG, Do TH, Ahmad SM, Olsen LR, Klausen TW, Breinholt MF, Hansen M, Martinenaite E, Met Ö, Svane IM, Knudsen LM, Andersen MH
Frontiers in immunology 2020;11:595035
Frontiers in immunology 2020;11:595035
The Safety and Efficacy of Live Viral Vaccines in Patients With Cartilage-Hair Hypoplasia.
Vakkilainen S, Kleino I, Honkanen J, Salo H, Kainulainen L, Gräsbeck M, Kekäläinen E, Mäkitie O, Klemetti P
Frontiers in immunology 2020;11:2020
Frontiers in immunology 2020;11:2020
Pregnancy Gestation Impacts on HIV-1-Specific Granzyme B Response and Central Memory CD4 T Cells.
Cocker ATH, Shah NM, Raj I, Dermont S, Khan W, Mandalia S, Imami N, Johnson MR
Frontiers in immunology 2020;11:153
Frontiers in immunology 2020;11:153
Mucosal-Associated Invariant T Cells Develop an Innate-Like Transcriptomic Program in Anti-mycobacterial Responses.
Sharma M, Zhang S, Niu L, Lewinsohn DM, Zhang X, Huang S
Frontiers in immunology 2020;11:1136
Frontiers in immunology 2020;11:1136
Elevated nucleoprotein-induced interferon-γ release in COVID-19 patients detected in a SARS-CoV-2 enzyme-linked immunosorbent spot assay.
Thijsen S, Heron M, Gremmels H, van der Kieft R, Reusken C, Kremer K, Limonard G, Bossink A
The Journal of infection 2020 Sep;81(3):452-482
The Journal of infection 2020 Sep;81(3):452-482
An RNA vaccine drives immunity in checkpoint-inhibitor-treated melanoma.
Sahin U, Oehm P, Derhovanessian E, Jabulowsky RA, Vormehr M, Gold M, Maurus D, Schwarck-Kokarakis D, Kuhn AN, Omokoko T, Kranz LM, Diken M, Kreiter S, Haas H, Attig S, Rae R, Cuk K, Kemmer-Brück A, Breitkreuz A, Tolliver C, Caspar J, Quinkhardt J, Hebich L, Stein M, Hohberger A, Vogler I, Liebig I, Renken S, Sikorski J, Leierer M, Müller V, Mitzel-Rink H, Miederer M, Huber C, Grabbe S, Utikal J, Pinter A, Kaufmann R, Hassel JC, Loquai C, Türeci Ö
Nature 2020 Sep;585(7823):107-112
Nature 2020 Sep;585(7823):107-112
Reinventing the nutraceutical value of gluten: The case of l-theanine-gluten as a potential alternative to the gluten exclusion diet in celiac disease.
Ribeiro M, Lopes S, Picascia S, Gianfrani C, Nunes FM
Food chemistry 2020 Sep 15;324:126840
Food chemistry 2020 Sep 15;324:126840
Impaired Cellular Immune Responses During the First Week of Severe Acute Influenza Infection.
Turner JS, Lei T, Schmitz AJ, Day A, Choreño-Parra JA, Jiménez-Alvarez L, Cruz-Lagunas A, House SL, Zúñiga J, Ellebedy AH, Mudd PA
The Journal of infectious diseases 2020 Sep 1;222(7):1235-1244
The Journal of infectious diseases 2020 Sep 1;222(7):1235-1244
The MAIT TCRβ chain contributes to discrimination of microbial ligand.
Narayanan GA, McLaren JE, Meermeier EW, Ladell K, Swarbrick GM, Price DA, Tran JG, Worley AH, Vogt T, Wong EB, Lewinsohn DM
Immunology and cell biology 2020 Oct;98(9):770-781
Immunology and cell biology 2020 Oct;98(9):770-781
Breast cancer-induced immune suppression in the sentinel lymph node is effectively countered by CpG-B in conjunction with inhibition of the JAK2/STAT3 pathway.
van Pul KM, Vuylsteke RJCLM, de Beijer MTA, van de Ven R, van den Tol MP, Stockmann HBAC, de Gruijl TD
Journal for immunotherapy of cancer 2020 Oct;8(2)
Journal for immunotherapy of cancer 2020 Oct;8(2)
Characterization of amoxicillin and clavulanic acid specific T-cell clones from patients with immediate drug hypersensitivity.
Ariza A, Fernández-Santamaría R, Meng X, Salas M, Ogese MO, Tailor A, Bogas G, Torres MJ, Naisbitt DJ
Allergy 2020 Oct;75(10):2562-2573
Allergy 2020 Oct;75(10):2562-2573
COVID-19 vaccine BNT162b1 elicits human antibody and T(H)1 T cell responses.
Sahin U, Muik A, Derhovanessian E, Vogler I, Kranz LM, Vormehr M, Baum A, Pascal K, Quandt J, Maurus D, Brachtendorf S, Lörks V, Sikorski J, Hilker R, Becker D, Eller AK, Grützner J, Boesler C, Rosenbaum C, Kühnle MC, Luxemburger U, Kemmer-Brück A, Langer D, Bexon M, Bolte S, Karikó K, Palanche T, Fischer B, Schultz A, Shi PY, Fontes-Garfias C, Perez JL, Swanson KA, Loschko J, Scully IL, Cutler M, Kalina W, Kyratsous CA, Cooper D, Dormitzer PR, Jansen KU, Türeci Ö
Nature 2020 Oct;586(7830):594-599
Nature 2020 Oct;586(7830):594-599
Systemic and respiratory T-cells induced by seasonal H1N1 influenza protect against pandemic H2N2 in ferrets.
van de Ven K, de Heij F, van Dijken H, Ferreira JA, de Jonge J
Communications biology 2020 Oct 9;3(1):564
Communications biology 2020 Oct 9;3(1):564
Selective and cross-reactive SARS-CoV-2 T cell epitopes in unexposed humans.
Mateus J, Grifoni A, Tarke A, Sidney J, Ramirez SI, Dan JM, Burger ZC, Rawlings SA, Smith DM, Phillips E, Mallal S, Lammers M, Rubiro P, Quiambao L, Sutherland A, Yu ED, da Silva Antunes R, Greenbaum J, Frazier A, Markmann AJ, Premkumar L, de Silva A, Peters B, Crotty S, Sette A, Weiskopf D
Science (New York, N.Y.) 2020 Oct 2;370(6512):89-94
Science (New York, N.Y.) 2020 Oct 2;370(6512):89-94
Healthy Donors Harbor Memory T Cell Responses to RAS Neo-Antigens.
Holmström MO, Andersen MH
Cancers 2020 Oct 19;12(10)
Cancers 2020 Oct 19;12(10)
The vitamin D analogue calcipotriol promotes an anti-tumorigenic phenotype of human pancreatic CAFs but reduces T cell mediated immunity.
Gorchs L, Ahmed S, Mayer C, Knauf A, Fernández Moro C, Svensson M, Heuchel R, Rangelova E, Bergman P, Kaipe H
Scientific reports 2020 Oct 15;10(1):17444
Scientific reports 2020 Oct 15;10(1):17444
Robust T Cell Immunity in Convalescent Individuals with Asymptomatic or Mild COVID-19.
Sekine T, Perez-Potti A, Rivera-Ballesteros O, Strålin K, Gorin JB, Olsson A, Llewellyn-Lacey S, Kamal H, Bogdanovic G, Muschiol S, Wullimann DJ, Kammann T, Emgård J, Parrot T, Folkesson E, Karolinska COVID-19 Study Group, Rooyackers O, Eriksson LI, Henter JI, Sönnerborg A, Allander T, Albert J, Nielsen M, Klingström J, Gredmark-Russ S, Björkström NK, Sandberg JK, Price DA, Ljunggren HG, Aleman S, Buggert M
Cell 2020 Oct 1;183(1):158-168.e14
Cell 2020 Oct 1;183(1):158-168.e14
In vitro 4-1BB stimulation promotes expansion of CD8(+) tumor-infiltrating lymphocytes from various sarcoma subtypes.
Nielsen M, Krarup-Hansen A, Hovgaard D, Petersen MM, Loya AC, Westergaard MCW, Svane IM, Junker N
Cancer immunology, immunotherapy : CII 2020 Nov;69(11):2179-2191
Cancer immunology, immunotherapy : CII 2020 Nov;69(11):2179-2191
Immune suppression caused by PD-L2 expression on tumor cells in gastric cancer.
Nakayama Y, Mimura K, Kua LF, Okayama H, Min AKT, Saito K, Hanayama H, Watanabe Y, Saito M, Momma T, Saze Z, Ohki S, Suzuki Y, Ichikawa D, Yong WP, Kono K
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2020 Nov;23(6):961-973
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2020 Nov;23(6):961-973
Antigen-reactive regulatory T cells can be expanded in vitro with monocytes and anti-CD28 and anti-CD154 antibodies.
Iwaszkiewicz-Grzes D, Gliwinski M, Eugster A, Piotrowska M, Dahl A, Marek-Trzonkowska N, Trzonkowski P
Cytotherapy 2020 Nov;22(11):629-641
Cytotherapy 2020 Nov;22(11):629-641
Hazara virus and Crimean-Congo Hemorrhagic Fever Virus show a different pattern of entry in fully-polarized Caco-2 cell line.
Monteil V, Salata C, Appelberg S, Mirazimi A
PLoS neglected tropical diseases 2020 Nov;14(11):e0008863
PLoS neglected tropical diseases 2020 Nov;14(11):e0008863
Varicella-zoster-virus vaccination of immunosuppressed children with inflammatory bowel disease or autoimmune hepatitis: A prospective observational study.
Seitel T, Cagol L, Prelog M, Frivolt K, Krahl A, Trenkel S, Speth F, Mayer B, Almanzar G, Koletzko S, Debatin KM, Mertens T, Posovszky C
Vaccine 2020 Nov 25;38(50):8024-8031
Vaccine 2020 Nov 25;38(50):8024-8031
Virus-specific T-cell therapy to treat BK polyomavirus infection in bone marrow and solid organ transplant recipients.
Nelson AS, Heyenbruch D, Rubinstein JD, Sabulski A, Jodele S, Thomas S, Lutzko C, Zhu X, Leemhuis T, Cancelas JA, Keller M, Bollard CM, Hanley PJ, Davies SM, Grimley MS
Blood advances 2020 Nov 24;4(22):5745-5754
Blood advances 2020 Nov 24;4(22):5745-5754
Identification and Characterization of CD4(+) T Cell Epitopes after Shingrix Vaccination.
Voic H, de Vries RD, Sidney J, Rubiro P, Moore E, Phillips E, Mallal S, Schwan B, Weiskopf D, Sette A, Grifoni A
Journal of virology 2020 Nov 23;94(24)
Journal of virology 2020 Nov 23;94(24)
mRNA vaccine-induced neoantigen-specific T cell immunity in patients with gastrointestinal cancer.
Cafri G, Gartner JJ, Zaks T, Hopson K, Levin N, Paria BC, Parkhurst MR, Yossef R, Lowery FJ, Jafferji MS, Prickett TD, Goff SL, McGowan CT, Seitter S, Shindorf ML, Parikh A, Chatani PD, Robbins PF, Rosenberg SA
The Journal of clinical investigation 2020 Nov 2;130(11):5976-5988
The Journal of clinical investigation 2020 Nov 2;130(11):5976-5988
TruNeo: an integrated pipeline improves personalized true tumor neoantigen identification.
Tang Y, Wang Y, Wang J, Li M, Peng L, Wei G, Zhang Y, Li J, Gao Z
BMC bioinformatics 2020 Nov 18;21(1):532
BMC bioinformatics 2020 Nov 18;21(1):532
Identification of Novel Yellow Fever Class II Epitopes in YF-17D Vaccinees.
Mateus J, Grifoni A, Voic H, Angelo MA, Phillips E, Mallal S, Sidney J, Sette A, Weiskopf D
Viruses 2020 Nov 12;12(11)
Viruses 2020 Nov 12;12(11)
HLA DRB1*15:01-DQB1*06:02-Restricted Human CD4+ T Cells Are Selectively Activated With Amoxicillin-Peptide Adducts.
Tailor A, Meng X, Adair K, Farrell J, Waddington JC, Daly A, Pirmohamed M, Dear G, Park BK, Naisbitt DJ
Toxicological sciences : an official journal of the Society of Toxicology 2020 Nov 1;178(1):115-126
Toxicological sciences : an official journal of the Society of Toxicology 2020 Nov 1;178(1):115-126
Personalized neoantigen-based immunotherapy for advanced collecting duct carcinoma: case report.
Zeng Y, Zhang W, Li Z, Zheng Y, Wang Y, Chen G, Qiu L, Ke K, Su X, Cai Z, Liu J, Liu X
Journal for immunotherapy of cancer 2020 May;8(1)
Journal for immunotherapy of cancer 2020 May;8(1)
Characterisation of clinical and immune reactivity to barley and rye ingestion in children with coeliac disease.
Hardy MY, Russell AK, Pizzey C, Jones CM, Watson KA, La Gruta NL, Cameron DJ, Tye-Din JA
Gut 2020 May;69(5):830-840
Gut 2020 May;69(5):830-840
Reader-free ELISPOT assay for immuno-monitoring in peptide-based cancer vaccine immunotherapy.
Hayashi S, Imanishi R, Adachi M, Ikejima S, Nakata J, Morimoto S, Fujiki F, Nishida S, Tsuboi A, Hosen N, Nakajima H, Hasegawa K, Oka Y, Sugiyama H, Oji Y
Biomedical reports 2020 May;12(5):244-250
Biomedical reports 2020 May;12(5):244-250
Cathepsin S Alterations Induce a Tumor-Promoting Immune Microenvironment in Follicular Lymphoma.
Bararia D, Hildebrand JA, Stolz S, Haebe S, Alig S, Trevisani CP, Osorio-Barrios F, Bartoschek MD, Mentz M, Pastore A, Gaitzsch E, Heide M, Jurinovic V, Rautter K, Gunawardana J, Sabdia MB, Szczepanowski M, Richter J, Klapper W, Louissaint A Jr, Ludwig C, Bultmann S, Leonhardt H, Eustermann S, Hopfner KP, Hiddemann W, von Bergwelt-Baildon M, Steidl C, Kridel R, Tobin JWD, Gandhi MK, Weinstock DM, Schmidt-Supprian M, Sárosi MB, Rudelius M, Passerini V, Mautner J, Weigert O
Cell reports 2020 May 5;31(5):107522
Cell reports 2020 May 5;31(5):107522
Ligand-dependent downregulation of MR1 cell surface expression.
Salio M, Awad W, Veerapen N, Gonzalez-Lopez C, Kulicke C, Waithe D, Martens AWJ, Lewinsohn DM, Hobrath JV, Cox LR, Rossjohn J, Besra GS, Cerundolo V
Proceedings of the National Academy of Sciences of the United States of America 2020 May 12;117(19):10465-10475
Proceedings of the National Academy of Sciences of the United States of America 2020 May 12;117(19):10465-10475
Phase II study of α-galactosylceramide-pulsed antigen-presenting cells in patients with advanced or recurrent non-small cell lung cancer.
Toyoda T, Kamata T, Tanaka K, Ihara F, Takami M, Suzuki H, Nakajima T, Ikeuchi T, Kawasaki Y, Hanaoka H, Nakayama T, Yoshino I, Motohashi S
Journal for immunotherapy of cancer 2020 Mar;8(1)
Journal for immunotherapy of cancer 2020 Mar;8(1)
Human Immune Responses to Melioidosis and Cross-Reactivity to Low-Virulence Burkholderia Species, Thailand(1).
Rongkard P, Kronsteiner B, Hantrakun V, Jenjaroen K, Sumonwiriya M, Chaichana P, Chumseng S, Chantratita N, Wuthiekanun V, Fletcher HA, Teparrukkul P, Limmathurotsakul D, Day NPJ, Dunachie SJ
Emerging infectious diseases 2020 Mar;26(3):463-471
Emerging infectious diseases 2020 Mar;26(3):463-471
A novel α-fetoprotein-derived helper T-lymphocyte epitope with strong immunogenicity in patients with hepatocellular carcinoma.
Tamai T, Mizukoshi E, Kumagai M, Terashima T, Iida N, Kitahara M, Shimakami T, Kitamura K, Arai K, Yamashita T, Sakai Y, Yamashita T, Honda M, Fushimi K, Kaneko S
Scientific reports 2020 Mar 4;10(1):4021
Scientific reports 2020 Mar 4;10(1):4021
Assessing the impact of AGS-004, a dendritic cell-based immunotherapy, and vorinostat on persistent HIV-1 Infection.
Gay CL, Kuruc JD, Falcinelli SD, Warren JA, Reifeis SA, Kirchherr JL, James KS, Dewey MG, Helms A, Allard B, Stuelke E, Gamble A, Plachco A, Gorelick RJ, Eron JJ, Hudgens M, Garrido C, Goonetilleke N, DeBenedette MA, Tcherepanova IY, Nicolette CA, Archin NM, Margolis DM
Scientific reports 2020 Mar 20;10(1):5134
Scientific reports 2020 Mar 20;10(1):5134
Human Immunodeficiency Virus Exposure but Not Early Cytomegalovirus Infection Is Associated With Increased Hospitalization and Decreased Memory T-Cell Responses to Tetanus Vaccine.
Smith C, Moraka NO, Ibrahim M, Moyo S, Mayondi G, Kammerer B, Leidner J, Gaseitsiwe S, Li S, Shapiro R, Lockman S, Weinberg A
The Journal of infectious diseases 2020 Mar 16;221(7):1167-1175
The Journal of infectious diseases 2020 Mar 16;221(7):1167-1175
Safety, immunogenicity, and clinical efficacy of durvalumab in combination with folate receptor alpha vaccine TPIV200 in patients with advanced ovarian cancer: a phase II trial.
Zamarin D, Walderich S, Holland A, Zhou Q, Iasonos AE, Torrisi JM, Merghoub T, Chesebrough LF, Mcdonnell AS, Gallagher JM, Li Y, Hollmann TJ, Grisham RN, Erskine CL, Block MS, Knutson KL, O'Cearbhaill RE, Aghajanian C, Konner JA
Journal for immunotherapy of cancer 2020 Jun;8(1)
Journal for immunotherapy of cancer 2020 Jun;8(1)
Oncolytic Newcastle disease virus activation of the innate immune response and priming of antitumor adaptive responses in vitro.
Burke S, Shergold A, Elder MJ, Whitworth J, Cheng X, Jin H, Wilkinson RW, Harper J, Carroll DK
Cancer immunology, immunotherapy : CII 2020 Jun;69(6):1015-1027
Cancer immunology, immunotherapy : CII 2020 Jun;69(6):1015-1027
Experimental Antiglomerular Basement Membrane GN Induced by a Peptide from Actinomyces.
Gu QH, Huynh M, Shi Y, Jia XY, Luo JJ, Jiang TJ, Cui Z, Ooi JD, Kitching AR, Zhao MH
Journal of the American Society of Nephrology : JASN 2020 Jun;31(6):1282-1295
Journal of the American Society of Nephrology : JASN 2020 Jun;31(6):1282-1295
Quantitative and Qualitative Perturbations of CD8(+) MAITs in Healthy Mycobacterium tuberculosis-Infected Individuals.
Pomaznoy M, Kuan R, Lindvall M, Burel JG, Seumois G, Vijayanand P, Taplitz R, Gilman RH, Saito M, Lewinsohn DM, Sette A, Peters B, Lindestam Arlehamn CS
ImmunoHorizons 2020 Jun 4;4(6):292-307
ImmunoHorizons 2020 Jun 4;4(6):292-307
Detection of SARS-CoV-2-Specific Humoral and Cellular Immunity in COVID-19 Convalescent Individuals.
Ni L, Ye F, Cheng ML, Feng Y, Deng YQ, Zhao H, Wei P, Ge J, Gou M, Li X, Sun L, Cao T, Wang P, Zhou C, Zhang R, Liang P, Guo H, Wang X, Qin CF, Chen F, Dong C
Immunity 2020 Jun 16;52(6):971-977.e3
Immunity 2020 Jun 16;52(6):971-977.e3
Human CLEC9A antibodies deliver NY-ESO-1 antigen to CD141(+) dendritic cells to activate naïve and memory NY-ESO-1-specific CD8(+) T cells.
Masterman KA, Haigh OL, Tullett KM, Leal-Rojas IM, Walpole C, Pearson FE, Cebon J, Schmidt C, O'Brien L, Rosendahl N, Daraj G, Caminschi I, Gschweng EH, Hollis RP, Kohn DB, Lahoud MH, Radford KJ
Journal for immunotherapy of cancer 2020 Jul;8(2)
Journal for immunotherapy of cancer 2020 Jul;8(2)
Experimental treatment of colorectal cancer in mice with human T cells electroporated with NKG2D RNA CAR.
Li Z, Chi Z, Ang WX, Chen C, Tay JC, Ng YY, Xu X, Wang J, Zhu J, Wang S
Immunotherapy 2020 Jul;12(10):733-748
Immunotherapy 2020 Jul;12(10):733-748
Toll-like receptor dual-acting agonists are potent inducers of PBMC-produced cytokines that inhibit hepatitis B virus production in primary human hepatocytes.
Janovec V, Hodek J, Clarova K, Hofman T, Dostalik P, Fronek J, Chlupac J, Chaperot L, Durand S, Baumert TF, Pichova I, Lubyova B, Hirsch I, Weber J
Scientific reports 2020 Jul 29;10(1):12767
Scientific reports 2020 Jul 29;10(1):12767
Interrogating the recognition landscape of a conserved HIV-specific TCR reveals distinct bacterial peptide cross-reactivity.
Mendoza JL, Fischer S, Gee MH, Lam LH, Brackenridge S, Powrie FM, Birnbaum M, McMichael AJ, Garcia KC, Gillespie GM
eLife 2020 Jul 27;9
eLife 2020 Jul 27;9
Cancer Antigen Discovery Is Enabled by RNA Sequencing of Highly Purified Malignant and Nonmalignant Cells.
Scurr MJ, Greenshields-Watson A, Campbell E, Somerville MS, Chen Y, Hulin-Curtis SL, Burnell SEA, Davies JA, Davies MM, Hargest R, Phillips S, Christian AD, Ashelford KE, Andrews R, Parker AL, Stanton RJ, Gallimore A, Godkin A
Clinical cancer research : an official journal of the American Association for Cancer Research 2020 Jul 1;26(13):3360-3370
Clinical cancer research : an official journal of the American Association for Cancer Research 2020 Jul 1;26(13):3360-3370
Cinnamon extract inhibits allergen-specific immune responses in human and murine allergy models.
Ose R, Tu J, Schink A, Maxeiner J, Schuster P, Lucas K, Saloga J, Bellinghausen I
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2020 Jan;50(1):41-50
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2020 Jan;50(1):41-50
Interferon-γ Secretion Enzyme-Linked Immunospot Assay Determined Among Human T Cell Lymphotropic Virus Type 1-Infected Subjects: A Potential Laboratory Marker for Early HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis Diagnosis.
Apoliano CF, Assone T, Maciel da Silva BC, Andreetta Corral M, de Oliveira ACP, Fonseca LAM, Duarte AJDS, Tang Y, Casseb J
AIDS research and human retroviruses 2020 Jan;36(1):6-7
AIDS research and human retroviruses 2020 Jan;36(1):6-7
T cell receptor cross-reactivity between gliadin and bacterial peptides in celiac disease.
Petersen J, Ciacchi L, Tran MT, Loh KL, Kooy-Winkelaar Y, Croft NP, Hardy MY, Chen Z, McCluskey J, Anderson RP, Purcell AW, Tye-Din JA, Koning F, Reid HH, Rossjohn J
Nature structural & molecular biology 2020 Jan;27(1):49-61
Nature structural & molecular biology 2020 Jan;27(1):49-61
CD39(+) regulatory T cells modulate the immune response to carbamazepine in HLA-B*15:02 carriers.
Shen M, Lim JME, Chia C, Ren EC
Immunobiology 2020 Jan;225(1):151868
Immunobiology 2020 Jan;225(1):151868
Cell-Mediated Immunity Generated in Response to a Purified Inactivated Vaccine for Dengue Virus Type 1.
Friberg H, Martinez LJ, Lin L, Blaylock JM, De La Barrera RA, Rothman AL, Putnak JR, Eckels KH, Thomas SJ, Jarman RG, Currier JR
mSphere 2020 Jan 22;5(1)
mSphere 2020 Jan 22;5(1)
A phase I trial evaluating the safety and immunogenicity of a candidate tuberculosis vaccination regimen, ChAdOx1 85A prime - MVA85A boost in healthy UK adults.
Wilkie M, Satti I, Minhinnick A, Harris S, Riste M, Ramon RL, Sheehan S, Thomas ZM, Wright D, Stockdale L, Hamidi A, O'Shea MK, Dwivedi K, Behrens HM, Davenne T, Morton J, Vermaak S, Lawrie A, Moss P, McShane H
Vaccine 2020 Jan 22;38(4):779-789
Vaccine 2020 Jan 22;38(4):779-789
Characterization of virus-mediated immunogenic cancer cell death and the consequences for oncolytic virus-based immunotherapy of cancer.
Ma J, Ramachandran M, Jin C, Quijano-Rubio C, Martikainen M, Yu D, Essand M
Cell death & disease 2020 Jan 22;11(1):48
Cell death & disease 2020 Jan 22;11(1):48
Automated Flow Synthesis of Tumor Neoantigen Peptides for Personalized Immunotherapy.
Truex NL, Holden RL, Wang BY, Chen PG, Hanna S, Hu Z, Shetty K, Olive O, Neuberg D, Hacohen N, Keskin DB, Ott PA, Wu CJ, Pentelute BL
Scientific reports 2020 Jan 20;10(1):723
Scientific reports 2020 Jan 20;10(1):723
Epitope-specific airway-resident CD4+ T cell dynamics during experimental human RSV infection.
Guvenel A, Jozwik A, Ascough S, Ung SK, Paterson S, Kalyan M, Gardener Z, Bergstrom E, Kar S, Habibi MS, Paras A, Zhu J, Park M, Dhariwal J, Almond M, Wong EH, Sykes A, Del Rosario J, Trujillo-Torralbo MB, Mallia P, Sidney J, Peters B, Kon OM, Sette A, Johnston SL, Openshaw PJ, Chiu C
The Journal of clinical investigation 2020 Jan 2;130(1):523-538
The Journal of clinical investigation 2020 Jan 2;130(1):523-538
Evaluation of Newcastle disease virus mediated dendritic cell activation and cross-priming tumor-specific immune responses ex vivo.
Xu Q, Rangaswamy US, Wang W, Robbins SH, Harper J, Jin H, Cheng X
International journal of cancer 2020 Jan 15;146(2):531-541
International journal of cancer 2020 Jan 15;146(2):531-541
Intratumoral Plasmid IL12 Electroporation Therapy in Patients with Advanced Melanoma Induces Systemic and Intratumoral T-cell Responses.
Greaney SK, Algazi AP, Tsai KK, Takamura KT, Chen L, Twitty CG, Zhang L, Paciorek A, Pierce RH, Le MH, Daud AI, Fong L
Cancer immunology research 2020 Feb;8(2):246-254
Cancer immunology research 2020 Feb;8(2):246-254
Human labour is associated with altered regulatory T cell function and maternal immune activation.
Shah NM, Edey LF, Imami N, Johnson MR
Clinical and experimental immunology 2020 Feb;199(2):182-200
Clinical and experimental immunology 2020 Feb;199(2):182-200
A high infectious simian adenovirus type 23 vector based vaccine efficiently protects common marmosets against Zika virus infection.
Luo S, Zhao W, Ma X, Zhang P, Liu B, Zhang L, Wang W, Wang Y, Fu Y, Allain JP, Li T, Li C
PLoS neglected tropical diseases 2020 Feb;14(2):e0008027
PLoS neglected tropical diseases 2020 Feb;14(2):e0008027
Mobilization of pre-existing polyclonal T cells specific to neoantigens but not self-antigens during treatment of a patient with melanoma with bempegaldesleukin and nivolumab.
Veatch JR, Singhi N, Jesernig B, Paulson KG, Zalevsky J, Iaccucci E, Tykodi SS, Riddell SR
Journal for immunotherapy of cancer 2020 Dec;8(2)
Journal for immunotherapy of cancer 2020 Dec;8(2)
Immunostimulatory oncolytic virotherapy for multiple myeloma targeting 4-1BB and/or CD40.
Wenthe J, Naseri S, Hellström AC, Wiklund HJ, Eriksson E, Loskog A
Cancer gene therapy 2020 Dec;27(12):948-959
Cancer gene therapy 2020 Dec;27(12):948-959
Antigenic competition in the generation of multi-virus-specific cell lines for immunotherapy of human cytomegalovirus, polyomavirus BK, Epstein-Barr virus and adenovirus infection in haematopoietic stem cell transplant recipients.
Roubalová K, Němečková Š, Kryštofová J, Hainz P, Pumannová M, Hamšíková E
Immunology letters 2020 Dec;228:64-69
Immunology letters 2020 Dec;228:64-69
Designed Ankyrin Repeat Protein (DARPin) to target chimeric antigen receptor (CAR)-redirected T cells towards CD4(+) T cells to reduce the latent HIV(+) cell reservoir.
Patasic L, Seifried J, Bezler V, Kaljanac M, Schneider IC, Schmitz H, Tondera C, Hartmann J, Hombach A, Buchholz CJ, Abken H, König R, Cichutek K
Medical microbiology and immunology 2020 Dec;209(6):681-691
Medical microbiology and immunology 2020 Dec;209(6):681-691
Comprehensive analysis of T cell immunodominance and immunoprevalence of SARS-CoV-2 epitopes in COVID-19 cases.
Tarke A, Sidney J, Kidd CK, Dan JM, Ramirez SI, Yu ED, Mateus J, da Silva Antunes R, Moore E, Rubiro P, Methot N, Phillips E, Mallal S, Frazier A, Rawlings SA, Greenbaum JA, Peters B, Smith DM, Crotty S, Weiskopf D, Grifoni A, Sette A
bioRxiv : the preprint server for biology 2020 Dec 9;
bioRxiv : the preprint server for biology 2020 Dec 9;
Interferon-α-Induced Dendritic Cells Generated with Human Platelet Lysate Exhibit Elevated Antigen Presenting Ability to Cytotoxic T Lymphocytes.
Date I, Koya T, Sakamoto T, Togi M, Kawaguchi H, Watanabe A, Kato T Jr, Shimodaira S
Vaccines 2020 Dec 24;9(1)
Vaccines 2020 Dec 24;9(1)
Discordant neutralizing antibody and T cell responses in asymptomatic and mild SARS-CoV-2 infection.
Reynolds CJ, Swadling L, Gibbons JM, Pade C, Jensen MP, Diniz MO, Schmidt NM, Butler DK, Amin OE, Bailey SNL, Murray SM, Pieper FP, Taylor S, Jones J, Jones M, Lee WJ, Rosenheim J, Chandran A, Joy G, Di Genova C, Temperton N, Lambourne J, Cutino-Moguel T, Andiapen M, Fontana M, Smit A, Semper A, O'Brien B, Chain B, Brooks T, Manisty C, Treibel T, Moon JC, COVIDsortium investigators, Noursadeghi M, COVIDsortium immune correlates network, Altmann DM, Maini MK, McKnight Á, Boyton RJ
Science immunology 2020 Dec 23;5(54)
Science immunology 2020 Dec 23;5(54)
HLA Class II Genotype Does Not Affect the Myelin Responsiveness of Multiple Sclerosis Patients.
Derdelinckx J, Nkansah I, Ooms N, Van Bruggen L, Emonds MP, Daniëls L, Reynders T, Willekens B, Cras P, Berneman ZN, Cools N
Cells 2020 Dec 17;9(12)
Cells 2020 Dec 17;9(12)
Shared Immunogenic Poly-Epitope Frameshift Mutations in Microsatellite Unstable Tumors.
Roudko V, Bozkus CC, Orfanelli T, McClain CB, Carr C, O'Donnell T, Chakraborty L, Samstein R, Huang KL, Blank SV, Greenbaum B, Bhardwaj N
Cell 2020 Dec 10;183(6):1634-1649.e17
Cell 2020 Dec 10;183(6):1634-1649.e17
Healthy donor T cell responses to common cold coronaviruses and SARS-CoV-2.
Woldemeskel BA, Kwaa AK, Garliss CC, Laeyendecker O, Ray SC, Blankson JN
The Journal of clinical investigation 2020 Dec 1;130(12):6631-6638
The Journal of clinical investigation 2020 Dec 1;130(12):6631-6638
Rapid tumor vaccine using Toll-like receptor-activated ovarian cancer ascites monocytes.
Adams SF, Grimm AJ, Chiang CL, Mookerjee A, Flies D, Jean S, McCann GA, Michaux J, Pak H, Huber F, Neal C, Dangaj D, Bassani-Sternberg M, Rusakiewicz S, Facciabene A, Coukos G, Gimotty PA, Kandalaft LE
Journal for immunotherapy of cancer 2020 Aug;8(2)
Journal for immunotherapy of cancer 2020 Aug;8(2)
SARS-CoV-2-specific T cell immunity in cases of COVID-19 and SARS, and uninfected controls.
Le Bert N, Tan AT, Kunasegaran K, Tham CYL, Hafezi M, Chia A, Chng MHY, Lin M, Tan N, Linster M, Chia WN, Chen MI, Wang LF, Ooi EE, Kalimuddin S, Tambyah PA, Low JG, Tan YJ, Bertoletti A
Nature 2020 Aug;584(7821):457-462
Nature 2020 Aug;584(7821):457-462
EBV renders B cells susceptible to HIV-1 in humanized mice.
McHugh D, Myburgh R, Caduff N, Spohn M, Kok YL, Keller CW, Murer A, Chatterjee B, Rühl J, Engelmann C, Chijioke O, Quast I, Shilaih M, Strouvelle VP, Neumann K, Menter T, Dirnhofer S, Lam JK, Hui KF, Bredl S, Schlaepfer E, Sorce S, Zbinden A, Capaul R, Lünemann JD, Aguzzi A, Chiang AK, Kempf W, Trkola A, Metzner KJ, Manz MG, Grundhoff A, Speck RF, Münz C
Life science alliance 2020 Aug;3(8)
Life science alliance 2020 Aug;3(8)
Generation of high-affinity CMV-specific T cells for adoptive immunotherapy using IL-2, IL-15, and IL-21.
Luo XH, Meng Q, Liu Z, Paraschoudi G
Clinical immunology (Orlando, Fla.) 2020 Aug;217:108456
Clinical immunology (Orlando, Fla.) 2020 Aug;217:108456
Immunogenicity and safety of a recombinant adenovirus type-5-vectored COVID-19 vaccine in healthy adults aged 18 years or older: a randomised, double-blind, placebo-controlled, phase 2 trial.
Zhu FC, Guan XH, Li YH, Huang JY, Jiang T, Hou LH, Li JX, Yang BF, Wang L, Wang WJ, Wu SP, Wang Z, Wu XH, Xu JJ, Zhang Z, Jia SY, Wang BS, Hu Y, Liu JJ, Zhang J, Qian XA, Li Q, Pan HX, Jiang HD, Deng P, Gou JB, Wang XW, Wang XH, Chen W
Lancet (London, England) 2020 Aug 15;396(10249):479-488
Lancet (London, England) 2020 Aug 15;396(10249):479-488
Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial.
Folegatti PM, Ewer KJ, Aley PK, Angus B, Becker S, Belij-Rammerstorfer S, Bellamy D, Bibi S, Bittaye M, Clutterbuck EA, Dold C, Faust SN, Finn A, Flaxman AL, Hallis B, Heath P, Jenkin D, Lazarus R, Makinson R, Minassian AM, Pollock KM, Ramasamy M, Robinson H, Snape M, Tarrant R, Voysey M, Green C, Douglas AD, Hill AVS, Lambe T, Gilbert SC, Pollard AJ, Oxford COVID Vaccine Trial Group
Lancet (London, England) 2020 Aug 15;396(10249):467-478
Lancet (London, England) 2020 Aug 15;396(10249):467-478
Coordinated In Vitro Release of Granulysin, Perforin and IFN-γ in TB and HIV/TB Co-Infection Associated with Clinical Outcomes before and after Anti-TB Treatment.
Pitabut N, Dhepakson P, Sakurada S, Keicho N, Khusmith S
Pathogens (Basel, Switzerland) 2020 Aug 14;9(8)
Pathogens (Basel, Switzerland) 2020 Aug 14;9(8)
Adaptive immune responses to SARS-CoV-2 infection in severe versus mild individuals.
Zhang F, Gan R, Zhen Z, Hu X, Li X, Zhou F, Liu Y, Chen C, Xie S, Zhang B, Wu X, Huang Z
Signal transduction and targeted therapy 2020 Aug 14;5(1):156
Signal transduction and targeted therapy 2020 Aug 14;5(1):156
Specific T-cell immune responses against colony-forming cells including leukemic progenitor cells of AML patients were increased by immune checkpoint inhibition.
Greiner J, Götz M, Hofmann S, Schrezenmeier H, Wiesneth M, Bullinger L, Döhner H, Schneider V
Cancer immunology, immunotherapy : CII 2020 Apr;69(4):629-640
Cancer immunology, immunotherapy : CII 2020 Apr;69(4):629-640
Bispecific antibody activated T cells: A newly developed T cells with enhanced proliferation ability and cytotoxicity.
Guo Q, Zhang Z, Zhao P, Zou S, Li L, Li N, Sun W, Wei X, Hou L, Yang Z, Gao D
Immunology letters 2020 Apr;220:79-87
Immunology letters 2020 Apr;220:79-87
Efficacy, immunogenicity, and safety of an oral influenza vaccine: a placebo-controlled and active-controlled phase 2 human challenge study.
Liebowitz D, Gottlieb K, Kolhatkar NS, Garg SJ, Asher JM, Nazareno J, Kim K, McIlwain DR, Tucker SN
The Lancet. Infectious diseases 2020 Apr;20(4):435-444
The Lancet. Infectious diseases 2020 Apr;20(4):435-444
Early Induction of Cross-Reactive CD8+ T-Cell Responses in Tonsils After Live-Attenuated Influenza Vaccination in Children.
Mohn KG, Brokstad KA, Islam S, Oftung F, Tøndel C, Aarstad HJ, Cox RJ
The Journal of infectious diseases 2020 Apr 7;221(9):1528-1537
The Journal of infectious diseases 2020 Apr 7;221(9):1528-1537
Sublethal Radiation Affects Antigen Processing and Presentation Genes to Enhance Immunogenicity of Cancer Cells.
Punnanitinont A, Kannisto ED, Matsuzaki J, Odunsi K, Yendamuri S, Singh AK, Patnaik SK
International journal of molecular sciences 2020 Apr 7;21(7)
International journal of molecular sciences 2020 Apr 7;21(7)
α-Synuclein-specific T cell reactivity is associated with preclinical and early Parkinson's disease.
Lindestam Arlehamn CS, Dhanwani R, Pham J, Kuan R, Frazier A, Rezende Dutra J, Phillips E, Mallal S, Roederer M, Marder KS, Amara AW, Standaert DG, Goldman JG, Litvan I, Peters B, Sulzer D, Sette A
Nature communications 2020 Apr 20;11(1):1875
Nature communications 2020 Apr 20;11(1):1875
Neoantigen responses, immune correlates, and favorable outcomes after ipilimumab treatment of patients with prostate cancer.
Subudhi SK, Vence L, Zhao H, Blando J, Yadav SS, Xiong Q, Reuben A, Aparicio A, Corn PG, Chapin BF, Pisters LL, Troncoso P, Tidwell RS, Thall P, Wu CJ, Zhang J, Logothetis CL, Futreal A, Allison JP, Sharma P
Science translational medicine 2020 Apr 1;12(537)
Science translational medicine 2020 Apr 1;12(537)
A durable protective immune response to wild-type measles virus infection of macaques is due to viral replication and spread in lymphoid tissues.
Lin WW, Moran E, Adams RJ, Sievers RE, Hauer D, Godin S, Griffin DE
Science translational medicine 2020 Apr 1;12(537)
Science translational medicine 2020 Apr 1;12(537)
Prominent T-Cell Responses against the Acetylcholine Receptor ε Subunit in Myasthenia Gravis.
Neuhaus O, Wiesmüller KH, Hartung HP, Wiendl H
Neurology research international 2019;2019:1969068
Neurology research international 2019;2019:1969068
TRAV1-2(+) CD8(+) T-cells including oligoconal expansions of MAIT cells are enriched in the airways in human tuberculosis.
Wong EB, Gold MC, Meermeier EW, Xulu BZ, Khuzwayo S, Sullivan ZA, Mahyari E, Rogers Z, Kløverpris H, Sharma PK, Worley AH, Lalloo U, Baijnath P, Ambaram A, Naidoo L, Suleman M, Madansein R, McLaren JE, Ladell K, Miners KL, Price DA, Behar SM, Nielsen M, Kasprowicz VO, Leslie A, Bishai WR, Ndung'u T, Lewinsohn DM
Communications biology 2019;2:203
Communications biology 2019;2:203
Variability in German Cockroach Extract Composition Greatly Impacts T Cell Potency in Cockroach-Allergic Donors.
Birrueta G, Frazier A, Pomés A, Glesner J, Filep S, Schal C, Jeong KY, McMurtrey C, Vander Schans T, Hildebrand WH, Busse P, Beigelman A, Bacharier LB, Peters B, Sette A, Schulten V
Frontiers in immunology 2019;10:313
Frontiers in immunology 2019;10:313
Successful engraftment of gene-corrected hematopoietic stem cells in non-conditioned patients with Fanconi anemia.
Río P, Navarro S, Wang W, Sánchez-Domínguez R, Pujol RM, Segovia JC, Bogliolo M, Merino E, Wu N, Salgado R, Lamana ML, Yañez RM, Casado JA, Giménez Y, Román-Rodríguez FJ, Álvarez L, Alberquilla O, Raimbault A, Guenechea G, Lozano ML, Cerrato L, Hernando M, Gálvez E, Hladun R, Giralt I, Barquinero J, Galy A, García de Andoín N, López R, Catalá A, Schwartz JD, Surrallés J, Soulier J, Schmidt M, Díaz de Heredia C, Sevilla J, Bueren JA
Nature medicine 2019 Sep;25(9):1396-1401
Nature medicine 2019 Sep;25(9):1396-1401
Generation of donor-derived Wilms tumor antigen 1-specific cytotoxic T lymphocytes with potent anti-leukemia activity for somatic cell therapy in children given haploidentical stem cell transplantation: a feasibility pre-clinical study.
Ferulli F, Tanzi M, Turin I, Montini E, Rosti V, Acquafredda G, Lisini D, Compagno F, Boghen S, Licari A, Marseglia G, Zecca M, Montagna D
Cytotherapy 2019 Sep;21(9):958-972
Cytotherapy 2019 Sep;21(9):958-972
E40, a novel microbial protease efficiently detoxifying gluten proteins, for the dietary management of gluten intolerance.
Cavaletti L, Taravella A, Carrano L, Carenzi G, Sigurtà A, Solinas N, Caro S, Stasio LD, Picascia S, Laezza M, Troncone R, Gianfrani C, Mamone G
Scientific reports 2019 Sep 11;9(1):13147
Scientific reports 2019 Sep 11;9(1):13147
Identification of Immunodominant HIV-1 Epitopes Presented by HLA-C*12:02, a Protective Allele, Using an Immunopeptidomics Approach.
Chikata T, Paes W, Akahoshi T, Partridge T, Murakoshi H, Gatanaga H, Ternette N, Oka S, Borrow P, Takiguchi M
Journal of virology 2019 Sep 1;93(17)
Journal of virology 2019 Sep 1;93(17)
Functional immune response to influenza H1N1 in children and adults after live attenuated influenza virus vaccination.
Islam S, Zhou F, Lartey S, Mohn KGI, Krammer F, Cox RJ, Brokstad KA
Scandinavian journal of immunology 2019 Oct;90(4):e12801
Scandinavian journal of immunology 2019 Oct;90(4):e12801
Development of a novel human phage display-derived anti-LAG3 scFv antibody targeting CD8(+) T lymphocyte exhaustion.
Ascione A, Arenaccio C, Mallano A, Flego M, Gellini M, Andreotti M, Fenwick C, Pantaleo G, Vella S, Federico M
BMC biotechnology 2019 Oct 17;19(1):67
BMC biotechnology 2019 Oct 17;19(1):67
Enhanced IFN-γ, but not IL-2, response to Mycobacterium tuberculosis antigens in HIV/latent TB co-infected patients on long-term HAART.
Desalegn G, Tsegaye A, Gebreegziabiher D, Aseffa A, Howe R
BMC immunology 2019 Oct 11;20(1):35
BMC immunology 2019 Oct 11;20(1):35
Robust prediction of HLA class II epitopes by deep motif deconvolution of immunopeptidomes.
Racle J, Michaux J, Rockinger GA, Arnaud M, Bobisse S, Chong C, Guillaume P, Coukos G, Harari A, Jandus C, Bassani-Sternberg M, Gfeller D
Nature biotechnology 2019 Nov;37(11):1283-1286
Nature biotechnology 2019 Nov;37(11):1283-1286
Secondary resistance to immunotherapy associated with β-catenin pathway activation or PTEN loss in metastatic melanoma.
Trujillo JA, Luke JJ, Zha Y, Segal JP, Ritterhouse LL, Spranger S, Matijevich K, Gajewski TF
Journal for immunotherapy of cancer 2019 Nov 8;7(1):295
Journal for immunotherapy of cancer 2019 Nov 8;7(1):295
Antigenic competition in CD4(+) T cell responses in a randomized, multicenter, double-blind clinical HIV vaccine trial.
Kallas EG, Grunenberg NA, Yu C, Manso B, Pantaleo G, Casapia M, Baden LR, Valencia J, Sobieszczyk M, Van Tieu H, Allen M, Hural J, Graham BS, Kublin J, Gilbert PB, Corey L, Goepfert PA, McElrath MJ, Johnson RP, Huang Y, Frahm N
Science translational medicine 2019 Nov 20;11(519)
Science translational medicine 2019 Nov 20;11(519)
A PBMC-Based System to Assess Human T Cell Responses to Influenza Vaccine Candidates In Vitro.
Tapia-Calle G, Born PA, Koutsoumpli G, Gonzalez-Rodriguez MI, Hinrichs WLJ, Huckriede ALW
Vaccines 2019 Nov 13;7(4)
Vaccines 2019 Nov 13;7(4)
Increased CD83 expression of CD34-positive monocytes in donors during peripheral blood stem cell mobilization in humans.
Nakasone H, Kikuchi M, Kawamura K, Akahoshi Y, Sato M, Kawamura S, Yoshino N, Takeshita J, Yoshimura K, Misaki Y, Gomyo A, Tanihara A, Kusuda M, Tamaki M, Kimura SI, Kako S, Kanda Y
Scientific reports 2019 Nov 11;9(1):16499
Scientific reports 2019 Nov 11;9(1):16499
Tofacitinib modulates the VZV-specific CD4+ T cell immune response in vitro in lymphocytes of patients with rheumatoid arthritis.
Almanzar G, Kienle F, Schmalzing M, Maas A, Tony HP, Prelog M
Rheumatology (Oxford, England) 2019 Nov 1;58(11):2051-2060
Rheumatology (Oxford, England) 2019 Nov 1;58(11):2051-2060
CD1b presents self and Borrelia burgdorferi diacylglycerols to human T cells.
Reinink P, Souter MNT, Cheng TY, van Gorkom T, Lenz S, Kubler-Kielb J, Strle K, Kremer K, Thijsen SFT, Steere AC, Godfrey DI, Pellicci DG, Moody DB, Van Rhijn I
European journal of immunology 2019 May;49(5):737-746
European journal of immunology 2019 May;49(5):737-746
Identification and characterization of a naïve CD8+ T cell repertoire for benzylpenicillin.
Bechara R, Maillere B, Joseph D, Weaver RJ, Pallardy M
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2019 May;49(5):636-643
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2019 May;49(5):636-643
Type 1-programmed dendritic cells drive antigen-specific latency reversal and immune elimination of persistent HIV-1.
Kristoff J, Palma ML, Garcia-Bates TM, Shen C, Sluis-Cremer N, Gupta P, Rinaldo CR, Mailliard RB
EBioMedicine 2019 May;43:295-306
EBioMedicine 2019 May;43:295-306
UVB-induced depletion of donor-derived dendritic cells prevents allograft rejection of immune-privileged hair follicles in humanized mice.
Kim JY, Kang BM, Lee JS, Park HJ, Wi HJ, Yoon JS, Ahn C, Shin S, Kim KH, Jung KC, Kwon O
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2019 May;19(5):1344-1355
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2019 May;19(5):1344-1355
Therapeutic Vaccination Refocuses T-cell Responses Towards Conserved Regions of HIV-1 in Early Treated Individuals (BCN 01 study).
Mothe B, Manzardo C, Sanchez-Bernabeu A, Coll P, Morón-López S, Puertas MC, Rosas-Umbert M, Cobarsi P, Escrig R, Perez-Alvarez N, Ruiz I, Rovira C, Meulbroek M, Crook A, Borthwick N, Wee EG, Yang H, Miró JM, Dorrell L, Clotet B, Martinez-Picado J, Brander C, Hanke T
EClinicalMedicine 2019 May-Jun;11:65-80
EClinicalMedicine 2019 May-Jun;11:65-80
Robust Identification of Suitable T-Cell Subsets for Personalized CMV-Specific T-Cell Immunotherapy Using CD45RA and CD62L Microbeads.
Mangare C, Tischer-Zimmermann S, Riese SB, Dragon AC, Prinz I, Blasczyk R, Maecker-Kolhoff B, Eiz-Vesper B
International journal of molecular sciences 2019 Mar 20;20(6)
International journal of molecular sciences 2019 Mar 20;20(6)
MR1 recycling and blockade of endosomal trafficking reveal distinguishable antigen presentation pathways between Mycobacterium tuberculosis infection and exogenously delivered antigens.
Karamooz E, Harriff MJ, Narayanan GA, Worley A, Lewinsohn DM
Scientific reports 2019 Mar 18;9(1):4797
Scientific reports 2019 Mar 18;9(1):4797
Evaluating in vivo efficacy - toxicity profile of TEG001 in humanized mice xenografts against primary human AML disease and healthy hematopoietic cells.
Johanna I, Straetemans T, Heijhuurs S, Aarts-Riemens T, Norell H, Bongiovanni L, de Bruin A, Sebestyen Z, Kuball J
Journal for immunotherapy of cancer 2019 Mar 12;7(1):69
Journal for immunotherapy of cancer 2019 Mar 12;7(1):69
Contrasting Roles of the PD-1 Signaling Pathway in Dendritic Cell-Mediated Induction and Regulation of HIV-1-Specific Effector T Cell Functions.
Garcia-Bates TM, Palma ML, Shen C, Gambotto A, Macatangay BJC, Ferris RL, Rinaldo CR, Mailliard RB
Journal of virology 2019 Mar 1;93(5)
Journal of virology 2019 Mar 1;93(5)
Development of T cell immunity to norovirus and rotavirus in children under five years of age.
Malm M, Hyöty H, Knip M, Vesikari T, Blazevic V
Scientific reports 2019 Mar 1;9(1):3199
Scientific reports 2019 Mar 1;9(1):3199
Role of Mycobacterium avium lysate INF-γ, IL-17, and IL-2 ELISPOT assays in diagnosing nontuberculous mycobacteria lymphadenitis in children.
Della Bella C, Venturini E, Devente S, Piccini P, Tapinassi S, Bianchi L, Grassi A, Benagiano M, Alnwaisri HFM, Montagnani C, Chiappini E, Bitter W, D'Elios MM, de Martino M, Galli L
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 2019 Jun;38(6):1113-1122
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 2019 Jun;38(6):1113-1122
Healthy Donors Exhibit a CD4 T Cell Repertoire Specific to the Immunogenic Human Hormone H2-Relaxin before Injection.
Azam A, Gallais Y, Mallart S, Illiano S, Duclos O, Prades C, Maillère B
Journal of immunology (Baltimore, Md. : 1950) 2019 Jun 15;202(12):3507-3513
Journal of immunology (Baltimore, Md. : 1950) 2019 Jun 15;202(12):3507-3513
Immunogenicity and safety of a new live attenuated herpes zoster vaccine (NBP608) compared to Zostavax® in healthy adults aged 50 years and older.
Choi WS, Choi JH, Jung DS, Choi HJ, Kim YS, Lee J, Jang HC, Shin EC, Park JS, Kim H, Cheong HJ
Vaccine 2019 Jun 12;37(27):3605-3610
Vaccine 2019 Jun 12;37(27):3605-3610
Five Years of Successful Inducible Transgene Expression Following Locoregional Adeno-Associated Virus Delivery in Nonhuman Primates with No Detectable Immunity.
Guilbaud M, Devaux M, Couzinié C, Le Duff J, Toromanoff A, Vandamme C, Jaulin N, Gernoux G, Larcher T, Moullier P, Le Guiner C, Adjali O
Human gene therapy 2019 Jul;30(7):802-813
Human gene therapy 2019 Jul;30(7):802-813
Role of human and porcine MHC DRB1 alleles in determining the intensity of individual human anti-pig T-cell responses.
Hundrieser J, Hein R, Pokoyski C, Brinkmann A, Düvel H, Dinkel A, Trautewig B, Siegert JF, Römermann D, Petersen B, Schwinzer R
Xenotransplantation 2019 Jul;26(4):e12523
Xenotransplantation 2019 Jul;26(4):e12523
Investigation of the role of typhoid toxin in acute typhoid fever in a human challenge model.
Gibani MM, Jones E, Barton A, Jin C, Meek J, Camara S, Galal U, Heinz E, Rosenberg-Hasson Y, Obermoser G, Jones C, Campbell D, Black C, Thomaides-Brears H, Darlow C, Dold C, Silva-Reyes L, Blackwell L, Lara-Tejero M, Jiao X, Stack G, Blohmke CJ, Hill J, Angus B, Dougan G, Galán J, Pollard AJ
Nature medicine 2019 Jul;25(7):1082-1088
Nature medicine 2019 Jul;25(7):1082-1088
Molecular properties of gp100-reactive T-cell receptors drive the cytokine profile and antitumor efficacy of transgenic host T cells.
Eby JM, Smith AR, Riley TP, Cosgrove C, Ankney CM, Henning SW, Paulos CM, Garrett-Mayer E, Luiten RM, Nishimura MI, Baker BM, Le Poole IC
Pigment cell & melanoma research 2019 Jan;32(1):68-78
Pigment cell & melanoma research 2019 Jan;32(1):68-78
Evaluation of interleukin-12 receptor β1 and interferon gamma receptor 1 deficiency in patients with disseminated BCG infection.
Pourakbari B, Hosseinpour Sadeghi R, Mahmoudi S, Parvaneh N, Keshavarz Valian S, Mamishi S
Allergologia et immunopathologia 2019 Jan-Feb;47(1):38-42
Allergologia et immunopathologia 2019 Jan-Feb;47(1):38-42
Persistence of Varicella-Zoster Virus Cell-Mediated Immunity After the Administration of a Second Dose of Live Herpes Zoster Vaccine.
Weinberg A, Popmihajlov Z, Schmader KE, Johnson MJ, Caldas Y, Salazar AT, Canniff J, McCarson BJ, Martin J, Pang L, Levin MJ
The Journal of infectious diseases 2019 Jan 7;219(2):335-338
The Journal of infectious diseases 2019 Jan 7;219(2):335-338
A T-cell receptor escape channel allows broad T-cell response to CD1b and membrane phospholipids.
Shahine A, Reinink P, Reijneveld JF, Gras S, Holzheimer M, Cheng TY, Minnaard AJ, Altman JD, Lenz S, Prandi J, Kubler-Kielb J, Moody DB, Rossjohn J, Van Rhijn I
Nature communications 2019 Jan 4;10(1):56
Nature communications 2019 Jan 4;10(1):56
Inhibition of Heme Oxygenase-1 Activity Enhances Wilms Tumor-1-Specific T-Cell Responses in Cancer Immunotherapy.
Schillingmann DA, Riese SB, Vijayan V, Tischer-Zimmermann S, Schmetzer H, Maecker-Kolhoff B, Blasczyk R, Immenschuh S, Eiz-Vesper B
International journal of molecular sciences 2019 Jan 23;20(3)
International journal of molecular sciences 2019 Jan 23;20(3)
Dose Optimization of H56:IC31 Vaccine for Tuberculosis-Endemic Populations. A Double-Blind, Placebo-controlled, Dose-Selection Trial.
Suliman S, Luabeya AKK, Geldenhuys H, Tameris M, Hoff ST, Shi Z, Tait D, Kromann I, Ruhwald M, Rutkowski KT, Shepherd B, Hokey D, Ginsberg AM, Hanekom WA, Andersen P, Scriba TJ, Hatherill M, H56-035 Trial Group
American journal of respiratory and critical care medicine 2019 Jan 15;199(2):220-231
American journal of respiratory and critical care medicine 2019 Jan 15;199(2):220-231
MicroRNAs of Epstein-Barr Virus Attenuate T-Cell-Mediated Immune Control In Vivo.
Murer A, Rühl J, Zbinden A, Capaul R, Hammerschmidt W, Chijioke O, Münz C
mBio 2019 Jan 15;10(1)
mBio 2019 Jan 15;10(1)
Impairment of Vα24-Jα18(+)Vβ11(+) natural killer T cells in adult acute lymphoblastic leukemia patients.
Zhao H, Li Z, Xie S, Luo Y, Zhou Y, Deng M, Zeng H, Zhao J, Yu L, Xu B
Experimental cell research 2019 Jan 1;374(1):69-75
Experimental cell research 2019 Jan 1;374(1):69-75
The nature of the human T cell response to the cancer antigen 5T4 is determined by the balance of regulatory and inflammatory T cells of the same antigen-specificity: implications for vaccine design.
Besneux M, Greenshields-Watson A, Scurr MJ, MacLachlan BJ, Christian A, Davies MM, Hargest R, Phillips S, Godkin A, Gallimore A
Cancer immunology, immunotherapy : CII 2019 Feb;68(2):247-256
Cancer immunology, immunotherapy : CII 2019 Feb;68(2):247-256
In vitro analysis of immunomodulatory effects of mesenchymal stem cell- and tumor cell -derived exosomes on recall antigen-specific responses.
Fathollahi A, Hashemi SM, Haji Molla Hoseini M, Yeganeh F
International immunopharmacology 2019 Feb;67:302-310
International immunopharmacology 2019 Feb;67:302-310
Specific T-cell receptor gene transfer enhances immune response: A potential therapeutic strategy for the control of human cytomegalovirus infection in immunocompromised patients.
Zhang R, Zhang Y, Hu J, Wu W, Chen X, Lu Z, Yang R, Huang Y, Fan J
Cellular immunology 2019 Feb;336:58-65
Cellular immunology 2019 Feb;336:58-65
Neoantigenic Potential of Complex Chromosomal Rearrangements in Mesothelioma.
Mansfield AS, Peikert T, Smadbeck JB, Udell JBM, Garcia-Rivera E, Elsbernd L, Erskine CL, Van Keulen VP, Kosari F, Murphy SJ, Ren H, Serla VV, Schaefer Klein JL, Karagouga G, Harris FR, Sosa C, Johnson SH, Nevala W, Markovic SN, Bungum AO, Edell ES, Dong H, Cheville JC, Aubry MC, Jen J, Vasmatzis G
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2019 Feb;14(2):276-287
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2019 Feb;14(2):276-287
Tumour-reactive T cell subsets in the microenvironment of ovarian cancer.
Westergaard MCW, Andersen R, Chong C, Kjeldsen JW, Pedersen M, Friese C, Hasselager T, Lajer H, Coukos G, Bassani-Sternberg M, Donia M, Svane IM
British journal of cancer 2019 Feb;120(4):424-434
British journal of cancer 2019 Feb;120(4):424-434
Mechanisms of Abrupt Loss of Virus Control in a Cohort of Previous HIV Controllers.
Rosás-Umbert M, Llano A, Bellido R, Olvera A, Ruiz-Riol M, Rocafort M, Fernández MA, Cobarsi P, Crespo M, Dorrell L, Del Romero J, Alcami J, Paredes R, Brander C, Mothe B
Journal of virology 2019 Feb 15;93(4)
Journal of virology 2019 Feb 15;93(4)
Efficacy of PD-1 blockade in cervical cancer is related to a CD8(+)FoxP3(+)CD25(+) T-cell subset with operational effector functions despite high immune checkpoint levels.
Heeren AM, Rotman J, Stam AGM, Pocorni N, Gassama AA, Samuels S, Bleeker MCG, Mom CH, Zijlmans HJMAA, Kenter GG, Jordanova ES, de Gruijl TD
Journal for immunotherapy of cancer 2019 Feb 12;7(1):43
Journal for immunotherapy of cancer 2019 Feb 12;7(1):43
Interferon Alpha Enhances NK Cell Function and the Suppressive Capacity of HIV-Specific CD8(+) T Cells.
Kwaa AKR, Talana CAG, Blankson JN
Journal of virology 2019 Feb 1;93(3)
Journal of virology 2019 Feb 1;93(3)
50-Gy Stereotactic Body Radiation Therapy to the Dominant Intraprostatic Nodule: Results From a Phase 1a/b Trial.
Herrera FG, Valerio M, Berthold D, Tawadros T, Meuwly JY, Vallet V, Baumgartner P, Thierry AC, De Bari B, Jichlinski P, Kandalaft L, Coukos G, Harari A, Bourhis J
International journal of radiation oncology, biology, physics 2019 Feb 1;103(2):320-334
International journal of radiation oncology, biology, physics 2019 Feb 1;103(2):320-334
Neoantigen-specific immunity in low mutation burden colorectal cancers of the consensus molecular subtype 4.
van den Bulk J, Verdegaal EME, Ruano D, Ijsselsteijn ME, Visser M, van der Breggen R, Duhen T, van der Ploeg M, de Vries NL, Oosting J, Peeters KCMJ, Weinberg AD, Farina-Sarasqueta A, van der Burg SH, de Miranda NFCC
Genome medicine 2019 Dec 30;11(1):87
Genome medicine 2019 Dec 30;11(1):87
Human leukocyte antigen (HLA) class II peptide flanking residues tune the immunogenicity of a human tumor-derived epitope.
MacLachlan BJ, Dolton G, Papakyriakou A, Greenshields-Watson A, Mason GH, Schauenburg A, Besneux M, Szomolay B, Elliott T, Sewell AK, Gallimore A, Rizkallah P, Cole DK, Godkin A
The Journal of biological chemistry 2019 Dec 27;294(52):20246-20258
The Journal of biological chemistry 2019 Dec 27;294(52):20246-20258
Early suppression of peripheral mononuclear blood cells in sepsis in response to stimulation with cytomegalovirus, OKT3, and pokeweed mitogen.
Malewicz NM, Walstein K, Heine T, Engler A, Bick A, Cox L, Dötsch A, Westendorf AM, Horn PA, Lindemann M, Peters J, Schäfer ST
Journal of applied physiology (Bethesda, Md. : 1985) 2019 Dec 1;127(6):1539-1547
Journal of applied physiology (Bethesda, Md. : 1985) 2019 Dec 1;127(6):1539-1547
The association of allergic sensitization patterns in early childhood with disease manifestations and immunological reactivity at 10 years of age.
Schulten V, Frazier A, Calatroni A, Kattan M, Bacharier LB, O'Connor GT, Sandel MT, Wood RA, Wheatley LM, Togias A, Visness CM, Dresen A, Gern JE, Sette A
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2019 Aug;49(8):1087-1094
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2019 Aug;49(8):1087-1094
The effects of CCR7 and related signaling pathways on Leishmania major -infected human dendritic cells.
Zhao Y, Dang Z, Wei R, Gui W, Zhang Y, Chong S
Journal of cellular physiology 2019 Aug;234(8):13145-13156
Journal of cellular physiology 2019 Aug;234(8):13145-13156
Generation of Zika virus-specific T cells from seropositive and virus-naïve donors for potential use as an autologous or "off-the-shelf" immunotherapeutic.
Hanajiri R, Sani GM, Hanley PJ, Silveira CG, Kallas EG, Keller MD, Bollard CM
Cytotherapy 2019 Aug;21(8):840-855
Cytotherapy 2019 Aug;21(8):840-855
Myelin oligodendrocyte glycoprotein revisited-sensitive detection of MOG-specific T-cells in multiple sclerosis.
Bronge M, Ruhrmann S, Carvalho-Queiroz C, Nilsson OB, Kaiser A, Holmgren E, Macrini C, Winklmeier S, Meinl E, Brundin L, Khademi M, Olsson T, Gafvelin G, Grönlund H
Journal of autoimmunity 2019 Aug;102:38-49
Journal of autoimmunity 2019 Aug;102:38-49
Chaperones of the class I peptide-loading complex facilitate the constitutive presentation of endogenous antigens on HLA-DP(84GGPM87).
Anczurowski M, Sugata K, Matsunaga Y, Yamashita Y, Wang CH, Guo T, Murata K, Saijo H, Kagoya Y, Saso K, Butler MO, Hirano N
Journal of autoimmunity 2019 Aug;102:114-125
Journal of autoimmunity 2019 Aug;102:114-125
The Effect of Age on the Immunogenicity of the Live Attenuated Zoster Vaccine Is Predicted by Baseline Regulatory T Cells and Varicella-Zoster Virus-Specific T Cell Immunity.
Weinberg A, Pang L, Johnson MJ, Caldas Y, Cho A, Tovar-Salazar A, Canniff J, Schmader KE, Popmihajlov Z, Levin MJ
Journal of virology 2019 Aug 1;93(15)
Journal of virology 2019 Aug 1;93(15)
Incomplete functional T-cell reconstitution in immunological non-responders at one year after initiation of antiretroviral therapy possibly predisposes them to infectious diseases.
Shete A, Dhayarkar S, Sangale S, Medhe U, Panchal N, Rahane G, Yelgate R, Dhamanage A, Gangakhedkar R
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 2019 Apr;81:114-122
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 2019 Apr;81:114-122
Leukoreduction system chambers are a reliable cellular source for the manufacturing of T-cell therapeutics.
Boudreau G, Carli C, Lamarche C, Rulleau C, Bonnaure G, Néron S, Delisle JS
Transfusion 2019 Apr;59(4):1300-1311
Transfusion 2019 Apr;59(4):1300-1311
HIV-1 reservoirs in urethral macrophages of patients under suppressive antiretroviral therapy.
Ganor Y, Real F, Sennepin A, Dutertre CA, Prevedel L, Xu L, Tudor D, Charmeteau B, Couedel-Courteille A, Marion S, Zenak AR, Jourdain JP, Zhou Z, Schmitt A, Capron C, Eugenin EA, Cheynier R, Revol M, Cristofari S, Hosmalin A, Bomsel M
Nature microbiology 2019 Apr;4(4):633-644
Nature microbiology 2019 Apr;4(4):633-644
Effective Suppression of HIV-1 Replication by Cytotoxic T Lymphocytes Specific for Pol Epitopes in Conserved Mosaic Vaccine Immunogens.
Zou C, Murakoshi H, Kuse N, Akahoshi T, Chikata T, Gatanaga H, Oka S, Hanke T, Takiguchi M
Journal of virology 2019 Apr 1;93(7)
Journal of virology 2019 Apr 1;93(7)
Characterization of Healthy Donor-Derived T-Cell Responses Specific to Telaprevir Diastereomers.
Alhilali KA, Al-Attar Z, Gibson A, Tailor A, Meng X, Monshouwer M, Snoeys J, Park BK, Naisbitt DJ
Toxicological sciences : an official journal of the Society of Toxicology 2019 Apr 1;168(2):597-609
Toxicological sciences : an official journal of the Society of Toxicology 2019 Apr 1;168(2):597-609
Immune Response and Intraocular Inflammation in Patients With Leber Hereditary Optic Neuropathy Treated With Intravitreal Injection of Recombinant Adeno-Associated Virus 2 Carrying the ND4 Gene: A Secondary Analysis of a Phase 1/2 Clinical Trial.
Bouquet C, Vignal Clermont C, Galy A, Fitoussi S, Blouin L, Munk MR, Valero S, Meunier S, Katz B, Sahel JA, Thomasson N
JAMA ophthalmology 2019 Apr 1;137(4):399-406
JAMA ophthalmology 2019 Apr 1;137(4):399-406
KIR3DL1-Negative CD8 T Cells and KIR3DL1-Negative Natural Killer Cells Contribute to the Advantageous Control of Early Human Immunodeficiency Virus Type 1 Infection in HLA-B Bw4 Homozygous Individuals.
Zhang X, Lu X, Moog C, Yuan L, Liu Z, Li Z, Xia W, Zhou Y, Wu H, Zhang T, Su B
Frontiers in immunology 2018;9:1855
Frontiers in immunology 2018;9:1855
A novel prostate cancer immunotherapy using prostate-specific antigen peptides and Candida skin test reagent as an adjuvant.
Abdallah AO, Coleman H, Kamel M, Davis R, Landrum T, Spencer H, Mackintosh S, Mahmoud FA, Milojkovic N, Wicker C, Arnaoutakis K, Nakagawa M
SAGE open medicine 2018;6:2050312118800202
SAGE open medicine 2018;6:2050312118800202
A heterogeneous human immunodeficiency virus-like particle (VLP) formulation produced by a novel vector system.
Pankrac J, Klein K, McKay PF, King DFL, Bain K, Knapp J, Biru T, Wijewardhana CN, Pawa R, Canaday DH, Gao Y, Fidler S, Shattock RJ, Arts EJ, Mann JFS
NPJ vaccines 2018;3:2
NPJ vaccines 2018;3:2
DNA immunization site determines the level of gene expression and the magnitude, but not the type of the induced immune response.
Petkov S, Starodubova E, Latanova A, Kilpeläinen A, Latyshev O, Svirskis S, Wahren B, Chiodi F, Gordeychuk I, Isaguliants M
PloS one 2018;13(6):e0197902
PloS one 2018;13(6):e0197902
The effect of acylation with fatty acids and other modifications on HLA class II:peptide binding and T cell stimulation for three model peptides.
Schultz HS, Østergaard S, Sidney J, Lamberth K, Sette A
PloS one 2018;13(5):e0197407
PloS one 2018;13(5):e0197407
Randomized phase I trial HIV-CORE 003: Depletion of serum amyloid P component and immunogenicity of DNA vaccination against HIV-1.
Borthwick NJ, Lane T, Moyo N, Crook A, Shim JM, Baines I, Wee EG, Hawkins PN, Gillmore JD, Hanke T, Pepys MB
PloS one 2018;13(5):e0197299
PloS one 2018;13(5):e0197299
Microbiota epitope similarity either dampens or enhances the immunogenicity of disease-associated antigenic epitopes.
Carrasco Pro S, Lindestam Arlehamn CS, Dhanda SK, Carpenter C, Lindvall M, Faruqi AA, Santee CA, Renz H, Sidney J, Peters B, Sette A
PloS one 2018;13(5):e0196551
PloS one 2018;13(5):e0196551
Cross-reactive microbial peptides can modulate HIV-specific CD8+ T cell responses.
Pohlmeyer CW, Laskey SB, Beck SE, Xu DC, Capoferri AA, Garliss CC, May ME, Livingston A, Lichmira W, Moore RD, Leffell MS, Butler NJ, Thorne JE, Flynn JA, Siliciano RF, Blankson JN
PloS one 2018;13(2):e0192098
PloS one 2018;13(2):e0192098
Immunotherapy with cancer peptides in combination with intravesical bacillus Calmette-Guerin for patients with non-muscle invasive bladder cancer.
Obara W, Hara I, Kato Y, Kato R, Inoue K, Sato F, Mimata H, Nakamura Y, Fujioka T
Cancer immunology, immunotherapy : CII 2018 Sep;67(9):1371-1380
Cancer immunology, immunotherapy : CII 2018 Sep;67(9):1371-1380
High background in ELISpot assays is associated with elevated levels of immune activation in HIV-1-seronegative individuals in Nairobi.
Liu AY, De Rosa SC, Guthrie BL, Choi RY, Kerubo-Bosire R, Richardson BA, Kiarie J, Farquhar C, Lohman-Payne B
Immunity, inflammation and disease 2018 Sep;6(3):392-401
Immunity, inflammation and disease 2018 Sep;6(3):392-401
Fumarate hydratase-specific T cell response in Chinese patients with autoimmune hepatitis.
Zhao Y, Li Y, Zhao D, Zhang H, Liu Y, Liao H, Zhang Y, Yan H
Clinics and research in hepatology and gastroenterology 2018 Sep;42(4):339-346
Clinics and research in hepatology and gastroenterology 2018 Sep;42(4):339-346
Immune response to human telomerase reverse transcriptase-derived helper T cell epitopes in hepatocellular carcinoma patients.
Kumagai M, Mizukoshi E, Tamai T, Kitahara M, Yamashita T, Arai K, Terashima T, Iida N, Fushimi K, Kaneko S
Liver international : official journal of the International Association for the Study of the Liver 2018 Sep;38(9):1635-1645
Liver international : official journal of the International Association for the Study of the Liver 2018 Sep;38(9):1635-1645
Combined Skin and Muscle DNA Priming Provides Enhanced Humoral Responses to a Human Immunodeficency Virus Type 1 Clade C Envelope Vaccine.
Cheeseman HM, Day S, McFarlane LR, Fleck S, Miller A, Cole T, Sousa-Santos N, Cope A, Cizmeci D, Tolazzi M, Hwekwete E, Hannaman D, Kratochvil S, McKay PF, Chung AW, Kent SJ, Cook A, Scarlatti G, Abraham S, Combadiere B, McCormack S, Lewis DJ, Shattock RJ
Human gene therapy 2018 Sep;29(9):1011-1028
Human gene therapy 2018 Sep;29(9):1011-1028
Retinal AAV8-RS1 Gene Therapy for X-Linked Retinoschisis: Initial Findings from a Phase I/IIa Trial by Intravitreal Delivery.
Cukras C, Wiley HE, Jeffrey BG, Sen HN, Turriff A, Zeng Y, Vijayasarathy C, Marangoni D, Ziccardi L, Kjellstrom S, Park TK, Hiriyanna S, Wright JF, Colosi P, Wu Z, Bush RA, Wei LL, Sieving PA
Molecular therapy : the journal of the American Society of Gene Therapy 2018 Sep 5;26(9):2282-2294
Molecular therapy : the journal of the American Society of Gene Therapy 2018 Sep 5;26(9):2282-2294
A randomized phase II clinical trial of dendritic cell vaccination following complete resection of colon cancer liver metastasis.
Rodriguez J, Castañón E, Perez-Gracia JL, Rodriguez I, Viudez A, Alfaro C, Oñate C, Perez G, Rotellar F, Inogés S, López-Diaz de Cerio A, Resano L, Ponz-Sarvise M, Rodriguez-Ruiz ME, Chopitea A, Vera R, Melero I
Journal for immunotherapy of cancer 2018 Sep 29;6(1):96
Journal for immunotherapy of cancer 2018 Sep 29;6(1):96
RNA editing derived epitopes function as cancer antigens to elicit immune responses.
Zhang M, Fritsche J, Roszik J, Williams LJ, Peng X, Chiu Y, Tsou CC, Hoffgaard F, Goldfinger V, Schoor O, Talukder A, Forget MA, Haymaker C, Bernatchez C, Han L, Tsang YH, Kong K, Xu X, Scott KL, Singh-Jasuja H, Lizee G, Liang H, Weinschenk T, Mills GB, Hwu P
Nature communications 2018 Sep 25;9(1):3919
Nature communications 2018 Sep 25;9(1):3919
Long-term remission despite clonal expansion of replication-competent HIV-1 isolates.
Veenhuis RT, Kwaa AK, Garliss CC, Latanich R, Salgado M, Pohlmeyer CW, Nobles CL, Gregg J, Scully EP, Bailey JR, Bushman FD, Blankson JN
JCI insight 2018 Sep 20;3(18)
JCI insight 2018 Sep 20;3(18)
Memory B Cells Activate Brain-Homing, Autoreactive CD4(+) T Cells in Multiple Sclerosis.
Jelcic I, Al Nimer F, Wang J, Lentsch V, Planas R, Jelcic I, Madjovski A, Ruhrmann S, Faigle W, Frauenknecht K, Pinilla C, Santos R, Hammer C, Ortiz Y, Opitz L, Grönlund H, Rogler G, Boyman O, Reynolds R, Lutterotti A, Khademi M, Olsson T, Piehl F, Sospedra M, Martin R
Cell 2018 Sep 20;175(1):85-100.e23
Cell 2018 Sep 20;175(1):85-100.e23
Enterobacteriaceae are essential for the modulation of colitis severity by fungi.
Sovran B, Planchais J, Jegou S, Straube M, Lamas B, Natividad JM, Agus A, Dupraz L, Glodt J, Da Costa G, Michel ML, Langella P, Richard ML, Sokol H
Microbiome 2018 Sep 1;6(1):152
Microbiome 2018 Sep 1;6(1):152
A novel allogeneic off-the-shelf dendritic cell vaccine for post-remission treatment of elderly patients with acute myeloid leukemia.
van de Loosdrecht AA, van Wetering S, Santegoets SJAM, Singh SK, Eeltink CM, den Hartog Y, Koppes M, Kaspers J, Ossenkoppele GJ, Kruisbeek AM, de Gruijl TD
Cancer immunology, immunotherapy : CII 2018 Oct;67(10):1505-1518
Cancer immunology, immunotherapy : CII 2018 Oct;67(10):1505-1518
Isolated adrenocorticotropic hormone deficiency as a form of paraneoplastic syndrome.
Bando H, Iguchi G, Kanie K, Nishizawa H, Matsumoto R, Fujita Y, Odake Y, Yoshida K, Suda K, Fukuoka H, Tanaka K, Ogawa W, Takahashi Y
Pituitary 2018 Oct;21(5):480-489
Pituitary 2018 Oct;21(5):480-489
Enhanced detection of neoantigen-reactive T cells targeting unique and shared oncogenes for personalized cancer immunotherapy.
Yossef R, Tran E, Deniger DC, Gros A, Pasetto A, Parkhurst MR, Gartner JJ, Prickett TD, Cafri G, Robbins PF, Rosenberg SA
JCI insight 2018 Oct 4;3(19)
JCI insight 2018 Oct 4;3(19)
Utilizing TAPBPR to promote exogenous peptide loading onto cell surface MHC I molecules.
Ilca FT, Neerincx A, Wills MR, de la Roche M, Boyle LH
Proceedings of the National Academy of Sciences of the United States of America 2018 Oct 2;115(40):E9353-E9361
Proceedings of the National Academy of Sciences of the United States of America 2018 Oct 2;115(40):E9353-E9361
Immune landscape and in vivo immunogenicity of NY-ESO-1 tumor antigen in advanced neuroblastoma patients.
Camisaschi C, Renne SL, Beretta V, Rini F, Spagnuolo RD, Tuccitto A, Podda MG, Parmiani G, Rivoltini L, Collini P, Castelli C, Luksch R
BMC cancer 2018 Oct 16;18(1):983
BMC cancer 2018 Oct 16;18(1):983
Antisense-Derived HIV-1 Cryptic Epitopes Are Not Major Drivers of Viral Evolution during the Acute Phase of Infection.
Peng BJ, Carlson JM, Liu MKP, Gao F, Goonetilleke N, McMichael AJ, Borrow P, Gilmour J, Heath SL, Hunter E, Bansal A, Goepfert PA
Journal of virology 2018 Oct 1;92(19)
Journal of virology 2018 Oct 1;92(19)
Th1 memory differentiates recombinant from live herpes zoster vaccines.
Levin MJ, Kroehl ME, Johnson MJ, Hammes A, Reinhold D, Lang N, Weinberg A
The Journal of clinical investigation 2018 Oct 1;128(10):4429-4440
The Journal of clinical investigation 2018 Oct 1;128(10):4429-4440
Ex Vivo Generation of Donor Antigen-Specific Immunomodulatory Cells: A Comparison Study of Anti-CD80/86 mAbs and CTLA4-lg Costimulatory Blockade.
Watanabe M, Kumagai-Braesch M, Yao M, Thunberg S, Berglund D, Sellberg F, Jorns C, Enoksson SL, Henriksson J, Lundgren T, Uhlin M, Berglund E, Ericzon BG
Cell transplantation 2018 Nov;27(11):1692-1704
Cell transplantation 2018 Nov;27(11):1692-1704
Cytokines concentrations in serum samples from allergic children-Multiple analysis to define biomarkers for better diagnosis of allergic inflammatory process.
Kordulewska NK, Cieślińska A, Fiedorowicz E, Jarmołowska B, Piskorz-Ogórek K, Kostyra E
Immunobiology 2018 Nov;223(11):648-657
Immunobiology 2018 Nov;223(11):648-657
Assessing and screening for T-cell epitopes from Mycobacterium tuberculosis RD2 proteins for the diagnosis of active tuberculosis.
Chen J, Ruan Q, Shen Y, Wang S, Shao L, Zhang W
The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases 2018 Nov-Dec;22(6):462-471
The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases 2018 Nov-Dec;22(6):462-471
Low-Density Lipoprotein-Reactive T Cells Regulate Plasma Cholesterol Levels and Development of Atherosclerosis in Humanized Hypercholesterolemic Mice.
Gisterå A, Klement ML, Polyzos KA, Mailer RKW, Duhlin A, Karlsson MCI, Ketelhuth DFJ, Hansson GK
Circulation 2018 Nov 27;138(22):2513-2526
Circulation 2018 Nov 27;138(22):2513-2526
CMV and EBV targets recognized by tumor-infiltrating B lymphocytes in pancreatic cancer and brain tumors.
Meng Q, Valentini D, Rao M, Dodoo E, Maeurer M
Scientific reports 2018 Nov 20;8(1):17079
Scientific reports 2018 Nov 20;8(1):17079
Strong and frequent T-cell responses to the minor allergen Phl p 12 in Spanish patients IgE-sensitized to Profilins.
Lund G, Brand S, Ramos T, Jimeno L, Boissy P, Vega F, Arina M, Christensen LH, Hoof I, Meno KH, Barber D, Blanco C, Würtzen PA, Andersen PS
Allergy 2018 May;73(5):1013-1021
Allergy 2018 May;73(5):1013-1021
The effect of splenectomy on the levels of PCV-13-induced memory B- and T cells.
Gazi U, Karasartova D, Sahiner IT, Gureser AS, Tosun O, Derici MK, Dolapci M, Taylan Ozkan A
International journal of clinical practice 2018 May;72(5):e13077
International journal of clinical practice 2018 May;72(5):e13077
IgG response to MHC class I epitope peptides is a quantitative predictive biomarker in the early course of treatment of colorectal cancer using therapeutic peptides.
Kanekiyo S, Hazama S, Takenouchi H, Nakajima M, Shindo Y, Matsui H, Tokumitsu Y, Tomochika S, Tsunedomi R, Tokuhisa Y, Iida M, Sakamoto K, Suzuki N, Takeda S, Yamamoto S, Yoshino S, Okuno K, Udaka K, Kawakami Y, Matsueda S, Ito K, Nagano H
Oncology reports 2018 May;39(5):2385-2392
Oncology reports 2018 May;39(5):2385-2392
Identification of two novel foot-and-mouth disease virus cytotoxic T lymphocyte epitopes that can bind six SLA-I proteins.
Gao FS, Zhai XX, Jiang P, Zhang Q, Gao H, Li ZB, Han Y, Yang J, Zhang ZH
Gene 2018 May 5;653:91-101
Gene 2018 May 5;653:91-101
Heat shock protein peptide complex-96 vaccination for newly diagnosed glioblastoma: a phase I, single-arm trial.
Ji N, Zhang Y, Liu Y, Xie J, Wang Y, Hao S, Gao Z
JCI insight 2018 May 17;3(10)
JCI insight 2018 May 17;3(10)
DOT1L inhibition attenuates graft-versus-host disease by allogeneic T cells in adoptive immunotherapy models.
Kagoya Y, Nakatsugawa M, Saso K, Guo T, Anczurowski M, Wang CH, Butler MO, Arrowsmith CH, Hirano N
Nature communications 2018 May 15;9(1):1915
Nature communications 2018 May 15;9(1):1915
Large-scale expansion of Vγ9Vδ2 T cells with engineered K562 feeder cells in G-Rex vessels and their use as chimeric antigen receptor-modified effector cells.
Xiao L, Chen C, Li Z, Zhu S, Tay JC, Zhang X, Zha S, Zeng J, Tan WK, Liu X, Chng WJ, Wang S
Cytotherapy 2018 Mar;20(3):420-435
Cytotherapy 2018 Mar;20(3):420-435
Human papilloma virus-specific T cells can be generated from naïve T cells for use as an immunotherapeutic strategy for immunocompromised patients.
McCormack SE, Cruz CRY, Wright KE, Powell AB, Lang H, Trimble C, Keller MD, Fuchs E, Bollard CM
Cytotherapy 2018 Mar;20(3):385-393
Cytotherapy 2018 Mar;20(3):385-393
Phenotypic and functional characterization of mesenchymal stromal cells isolated from pediatric patients with severe idiopathic nephrotic syndrome.
Starc N, Li M, Algeri M, Conforti A, Tomao L, Pitisci A, Emma F, Montini G, Messa P, Locatelli F, Bernardo ME, Vivarelli M
Cytotherapy 2018 Mar;20(3):322-334
Cytotherapy 2018 Mar;20(3):322-334
Adoptive cancer immunotherapy using DNA-demethylated T helper cells as antigen-presenting cells.
Kirkin AF, Dzhandzhugazyan KN, Guldberg P, Fang JJ, Andersen RS, Dahl C, Mortensen J, Lundby T, Wagner A, Law I, Broholm H, Madsen L, Lundell-Ek C, Gjerstorff MF, Ditzel HJ, Jensen MR, Fischer W
Nature communications 2018 Mar 6;9(1):785
Nature communications 2018 Mar 6;9(1):785
Mechanisms underlying the lack of endogenous processing and CLIP-mediated binding of the invariant chain by HLA-DP(84Gly).
Anczurowski M, Yamashita Y, Nakatsugawa M, Ochi T, Kagoya Y, Guo T, Wang CH, Rahman MA, Saso K, Butler MO, Hirano N
Scientific reports 2018 Mar 19;8(1):4804
Scientific reports 2018 Mar 19;8(1):4804
Sensitive and frequent identification of high avidity neo-epitope specific CD8 (+) T cells in immunotherapy-naive ovarian cancer.
Bobisse S, Genolet R, Roberti A, Tanyi JL, Racle J, Stevenson BJ, Iseli C, Michel A, Le Bitoux MA, Guillaume P, Schmidt J, Bianchi V, Dangaj D, Fenwick C, Derré L, Xenarios I, Michielin O, Romero P, Monos DS, Zoete V, Gfeller D, Kandalaft LE, Coukos G, Harari A
Nature communications 2018 Mar 15;9(1):1092
Nature communications 2018 Mar 15;9(1):1092
Donor-specific hypo-responsiveness occurs in simultaneous liver-kidney transplant recipients after the first year.
Taner T, Gustafson MP, Hansen MJ, Park WD, Bornschlegl S, Dietz AB, Stegall MD
Kidney international 2018 Jun;93(6):1465-1474
Kidney international 2018 Jun;93(6):1465-1474
A hypothesis for the existence of two types of tuberculosis, reflecting two distinct types of immune failure to control the pathogen, based upon prevalence of mycobacterium-specific IgG subclasses.
Menon J, Hoeppner VH, Judd A, Power CA, Bretscher PA
Scandinavian journal of immunology 2018 Jun;87(6):e12665
Scandinavian journal of immunology 2018 Jun;87(6):e12665
Quantitative T-cell repertoire analysis of peripheral blood mononuclear cells from lung cancer patients following long-term cancer peptide vaccination.
Takeda K, Kitaura K, Suzuki R, Owada Y, Muto S, Okabe N, Hasegawa T, Osugi J, Hoshino M, Tsunoda T, Okumura K, Suzuki H
Cancer immunology, immunotherapy : CII 2018 Jun;67(6):949-964
Cancer immunology, immunotherapy : CII 2018 Jun;67(6):949-964
Human T cell responses to Dengue and Zika virus infection compared to Dengue/Zika coinfection.
Badolato-Corrêa J, Sánchez-Arcila JC, Alves de Souza TM, Santos Barbosa L, Conrado Guerra Nunes P, da Rocha Queiroz Lima M, Gandini M, Bispo de Filippis AM, Venâncio da Cunha R, Leal de Azeredo E, de-Oliveira-Pinto LM
Immunity, inflammation and disease 2018 Jun;6(2):194-206
Immunity, inflammation and disease 2018 Jun;6(2):194-206
HLA mismatches that are identical for the antigen recognition domain are less immunogenic.
Roelen D, de Vaal Y, Vierra-Green C, Waldvogel S, Spellman S, Claas F, Oudshoorn M
Bone marrow transplantation 2018 Jun;53(6):729-740
Bone marrow transplantation 2018 Jun;53(6):729-740
Identification of HLA-A2-restricted immunogenic peptides derived from Vitamin D-Binding Protein.
Zhang M, Lu G, Meng F, Li S, Li X, Gong X
Cellular immunology 2018 Jun;328:18-23
Cellular immunology 2018 Jun;328:18-23
Immune recognition of somatic mutations leading to complete durable regression in metastatic breast cancer.
Zacharakis N, Chinnasamy H, Black M, Xu H, Lu YC, Zheng Z, Pasetto A, Langhan M, Shelton T, Prickett T, Gartner J, Jia L, Trebska-McGowan K, Somerville RP, Robbins PF, Rosenberg SA, Goff SL, Feldman SA
Nature medicine 2018 Jun;24(6):724-730
Nature medicine 2018 Jun;24(6):724-730
Reversibility of peripheral blood leukocyte phenotypic and functional changes after exposure to and withdrawal from tofacitinib, a Janus kinase inhibitor, in healthy volunteers.
Weinhold KJ, Bukowski JF, Brennan TV, Noveck RJ, Staats JS, Lin L, Stempora L, Hammond C, Wouters A, Mojcik CF, Cheng J, Collinge M, Jesson MI, Hazra A, Biswas P, Lan S, Clark JD, Hodge JA
Clinical immunology (Orlando, Fla.) 2018 Jun;191:10-20
Clinical immunology (Orlando, Fla.) 2018 Jun;191:10-20
Baseline immune profile by CyTOF can predict response to an investigational adjuvanted vaccine in elderly adults.
Lingblom CMD, Kowli S, Swaminathan N, Maecker HT, Lambert SL
Journal of translational medicine 2018 Jun 5;16(1):153
Journal of translational medicine 2018 Jun 5;16(1):153
Human Leukocyte Antigen-A Allele Distribution in Nasopharyngeal Carcinoma Patients Showing Anti-Melanoma-Associated Antigen A or Synovial Sarcoma X-2 T Cell Response in Blood.
Fan PW, Huang L, Chang XM, Feng YN, Yao X, Peng YC, Dong T, Wang RZ
Chinese medical journal 2018 Jun 5;131(11):1289-1295
Chinese medical journal 2018 Jun 5;131(11):1289-1295
Up-Regulation of T-Cell Activation MicroRNAs in Drug-Specific CD4(+) T-Cells from Hypersensitive Patients.
Monroy-Arreola A, Durán-Figueroa NV, Méndez-Flores S, Domínguez-Cherit J, Watkinson J, Badillo-Corona JA, Whitaker P, Naisbitt DJ, Castrejón-Flores JL
Chemical research in toxicology 2018 Jun 18;31(6):454-461
Chemical research in toxicology 2018 Jun 18;31(6):454-461
Variation at Extra-epitopic Amino Acid Residues Influences Suppression of Influenza Virus Replication by M1(58-66) Epitope-Specific CD8(+) T Lymphocytes.
van de Sandt CE, Pronk MR, van Baalen CA, Fouchier RAM, Rimmelzwaan GF
Journal of virology 2018 Jun 1;92(11)
Journal of virology 2018 Jun 1;92(11)
Validation of a CD1b tetramer assay for studies of human mycobacterial infection or vaccination.
Layton ED, Yu KKQ, Smith MT, Scriba TJ, De Rosa SC, Seshadri C
Journal of immunological methods 2018 Jul;458:44-52
Journal of immunological methods 2018 Jul;458:44-52
Cytokine Networks and Survivin Peptide-Specific Cellular Immune Responses Predict Improved Survival in Patients With Glioblastoma Multiforme.
Zhenjiang L, Rao M, Luo X, Valentini D, von Landenberg A, Meng Q, Sinclair G, Hoffmann N, Karbach J, Altmannsberger HM, Jäger E, Peredo IH, Dodoo E, Maeurer M
EBioMedicine 2018 Jul;33:49-56
EBioMedicine 2018 Jul;33:49-56
Survivin-peptide vaccination elicits immune response after allogeneic nonmyeloablative transplantation: a safe strategy to enhance the graft versus tumor effect.
Circosta P, Vitaggio K, Elia AR, Todorovic M, Sangiolo D, Carnevale-Schianca F, Vallario A, Geuna M, Aglietta M, Cignetti A
Immunotherapy 2018 Jul;10(9):753-767
Immunotherapy 2018 Jul;10(9):753-767
The Combined Utility of Ex Vivo IFN-γ Release Enzyme-Linked ImmunoSpot Assay and In Vivo Skin Testing in Patients with Antibiotic-Associated Severe Cutaneous Adverse Reactions.
Trubiano JA, Strautins K, Redwood AJ, Pavlos R, Konvinse KC, Aung AK, Slavin MA, Thursky KA, Grayson ML, Phillips EJ
The journal of allergy and clinical immunology. In practice 2018 Jul-Aug;6(4):1287-1296.e1
The journal of allergy and clinical immunology. In practice 2018 Jul-Aug;6(4):1287-1296.e1
Epstein-Barr virus- and cytomegalovirus-specific immune response in patients with brain cancer.
Liu Z, Poiret T, Meng Q, Rao M, von Landenberg A, Schoutrop E, Valentini D, Dodoo E, Peredo-Harvey I, Maeurer M
Journal of translational medicine 2018 Jul 3;16(1):182
Journal of translational medicine 2018 Jul 3;16(1):182
CD8(+) T cells specific for conserved, cross-reactive Gag epitopes with strong ability to suppress HIV-1 replication.
Murakoshi H, Zou C, Kuse N, Akahoshi T, Chikata T, Gatanaga H, Oka S, Hanke T, Takiguchi M
Retrovirology 2018 Jul 3;15(1):46
Retrovirology 2018 Jul 3;15(1):46
Co-expression of CD39 and CD103 identifies tumor-reactive CD8 T cells in human solid tumors.
Duhen T, Duhen R, Montler R, Moses J, Moudgil T, de Miranda NF, Goodall CP, Blair TC, Fox BA, McDermott JE, Chang SC, Grunkemeier G, Leidner R, Bell RB, Weinberg AD
Nature communications 2018 Jul 13;9(1):2724
Nature communications 2018 Jul 13;9(1):2724
Induction of Cross-Clade Antibody and T-Cell Responses by a Modified Vaccinia Virus Ankara-Based Influenza A(H5N1) Vaccine in a Randomized Phase 1/2a Clinical Trial.
de Vries RD, Altenburg AF, Nieuwkoop NJ, de Bruin E, van Trierum SE, Pronk MR, Lamers MM, Richard M, Nieuwenhuijse DF, Koopmans MPG, Kreijtz JHCM, Fouchier RAM, Osterhaus ADME, Sutter G, Rimmelzwaan GF
The Journal of infectious diseases 2018 Jul 13;218(4):614-623
The Journal of infectious diseases 2018 Jul 13;218(4):614-623
IFN-γ, CXCL16, uPAR: potential biomarkers for systemic lupus erythematosus.
Wen S, He F, Zhu X, Yuan S, Liu H, Sun L
Clinical and experimental rheumatology 2018 Jan-Feb;36(1):36-43
Clinical and experimental rheumatology 2018 Jan-Feb;36(1):36-43
Safety and Long-Term Efficacy of AAV4 Gene Therapy in Patients with RPE65 Leber Congenital Amaurosis.
Le Meur G, Lebranchu P, Billaud F, Adjali O, Schmitt S, Bézieau S, Péréon Y, Valabregue R, Ivan C, Darmon C, Moullier P, Rolling F, Weber M
Molecular therapy : the journal of the American Society of Gene Therapy 2018 Jan 3;26(1):256-268
Molecular therapy : the journal of the American Society of Gene Therapy 2018 Jan 3;26(1):256-268
Personalized adoptive immunotherapy for patients with EBV-associated tumors and complications: Evaluation of novel naturally processed and presented EBV-derived T-cell epitopes.
Bieling M, Tischer S, Kalinke U, Blasczyk R, Buus S, Maecker-Kolhoff B, Eiz-Vesper B
Oncotarget 2018 Jan 12;9(4):4737-4757
Oncotarget 2018 Jan 12;9(4):4737-4757
A phase I vaccination study with dendritic cells loaded with NY-ESO-1 and α-galactosylceramide: induction of polyfunctional T cells in high-risk melanoma patients.
Gasser O, Sharples KJ, Barrow C, Williams GM, Bauer E, Wood CE, Mester B, Dzhelali M, Caygill G, Jones J, Hayman CM, Hinder VA, Macapagal J, McCusker M, Weinkove R, Painter GF, Brimble MA, Findlay MP, Dunbar PR, Hermans IF
Cancer immunology, immunotherapy : CII 2018 Feb;67(2):285-298
Cancer immunology, immunotherapy : CII 2018 Feb;67(2):285-298
Sensitive detection of rare antigen-specific T cells directed against Wilms' tumor 1 by FluoroSpot assay.
Danielzik T, Koldehoff M, Buttkereit U, Beelen DW, Horn PA, Lindemann M
Leukemia & lymphoma 2018 Feb;59(2):490-492
Leukemia & lymphoma 2018 Feb;59(2):490-492
Intradermal HIV-1 DNA Immunization Using Needle-Free Zetajet Injection Followed by HIV-Modified Vaccinia Virus Ankara Vaccination Is Safe and Immunogenic in Mozambican Young Adults: A Phase I Randomized Controlled Trial.
Viegas EO, Tembe N, Nilsson C, Meggi B, Maueia C, Augusto O, Stout R, Scarlatti G, Ferrari G, Earl PL, Wahren B, Andersson S, Robb ML, Osman N, Biberfeld G, Jani I, Sandström E
AIDS research and human retroviruses 2018 Feb;34(2):193-205
AIDS research and human retroviruses 2018 Feb;34(2):193-205
Efficacy of intracellular immune checkpoint-silenced DC vaccine.
Wang D, Huang XF, Hong B, Song XT, Hu L, Jiang M, Zhang B, Ning H, Li Y, Xu C, Lou X, Li B, Yu Z, Hu J, Chen J, Yang F, Gao H, Ding G, Liao L, Rollins L, Jones L, Chen SY, Chen H
JCI insight 2018 Feb 8;3(3)
JCI insight 2018 Feb 8;3(3)
Hematopoiesis by iPSC-derived hematopoietic stem cells of aplastic anemia that escape cytotoxic T-cell attack.
Espinoza JL, Elbadry MI, Chonabayashi K, Yoshida Y, Katagiri T, Harada K, Nakagawa N, Zaimoku Y, Imi T, Takamatsu H, Ozawa T, Maruyama H, Hassanein HA, Khalifa A Noreldin A, Takenaka K, Akashi K, Hamana H, Kishi H, Akatsuka Y, Nakao S
Blood advances 2018 Feb 27;2(4):390-400
Blood advances 2018 Feb 27;2(4):390-400
Increased interferon-mediated immunity following in vitro and in vivo Modafinil treatment on peripheral immune cells.
Zager A, Brandão WN, Margatho RO, Cruz DSG, Peron JP, Tufik S, Andersen ML, Moresco M, Pizza F, Plazzi G, Kornum BR, Palermo-Neto J
Progress in neuro-psychopharmacology & biological psychiatry 2018 Feb 2;81:297-305
Progress in neuro-psychopharmacology & biological psychiatry 2018 Feb 2;81:297-305
Effective screening of T cells recognizing neoantigens and construction of T-cell receptor-engineered T cells.
Kato T, Matsuda T, Ikeda Y, Park JH, Leisegang M, Yoshimura S, Hikichi T, Harada M, Zewde M, Sato S, Hasegawa K, Kiyotani K, Nakamura Y
Oncotarget 2018 Feb 16;9(13):11009-11019
Oncotarget 2018 Feb 16;9(13):11009-11019
Extracellular Lactate: A Novel Measure of T Cell Proliferation.
Grist JT, Jarvis LB, Georgieva Z, Thompson S, Kaur Sandhu H, Burling K, Clarke A, Jackson S, Wills M, Gallagher FA, Jones JL
Journal of immunology (Baltimore, Md. : 1950) 2018 Feb 1;200(3):1220-1226
Journal of immunology (Baltimore, Md. : 1950) 2018 Feb 1;200(3):1220-1226
In Situ Gluten-Chitosan Interlocked Self-Assembled Supramolecular Architecture Reduces T-Cell-Mediated Immune Response to Gluten in Celiac Disease.
Ribeiro M, Picascia S, Rhazi L, Gianfrani C, Carrillo JM, Rodriguez-Quijano M, Branlard G, Nunes FM
Molecular nutrition & food research 2018 Dec;62(23):e1800646
Molecular nutrition & food research 2018 Dec;62(23):e1800646
Regulatory T cell abundance and activation status before and after priming with HIVIS-DNA and boosting with MVA-HIV/rgp140/GLA-AF may impact the magnitude of the vaccine-induced immune responses.
Chissumba RM, Luciano A, Namalango E, Bauer A, Bhatt N, Wahren B, Nilsson C, Geldmacher C, Scarlatti G, Jani I, Kestens L, TaMoVac II group
Immunobiology 2018 Dec;223(12):792-801
Immunobiology 2018 Dec;223(12):792-801
The effect of lipopolysaccharide on anti-inflammatory and pro-inflammatory cytokines production of human amniotic epithelial cells.
Motedayyen H, Fathi F, Fasihi-Ramandi M, Ali Taheri R
Reproductive biology 2018 Dec;18(4):404-409
Reproductive biology 2018 Dec;18(4):404-409
Immunogenic particles with a broad antigenic spectrum stimulate cytolytic T cells and offer increased protection against EBV infection ex vivo and in mice.
van Zyl DG, Tsai MH, Shumilov A, Schneidt V, Poirey R, Schlehe B, Fluhr H, Mautner J, Delecluse HJ
PLoS pathogens 2018 Dec;14(12):e1007464
PLoS pathogens 2018 Dec;14(12):e1007464
Deep learning using tumor HLA peptide mass spectrometry datasets improves neoantigen identification.
Bulik-Sullivan B, Busby J, Palmer CD, Davis MJ, Murphy T, Clark A, Busby M, Duke F, Yang A, Young L, Ojo NC, Caldwell K, Abhyankar J, Boucher T, Hart MG, Makarov V, Montpreville VT, Mercier O, Chan TA, Scagliotti G, Bironzo P, Novello S, Karachaliou N, Rosell R, Anderson I, Gabrail N, Hrom J, Limvarapuss C, Choquette K, Spira A, Rousseau R, Voong C, Rizvi NA, Fadel E, Frattini M, Jooss K, Skoberne M, Francis J, Yelensky R
Nature biotechnology 2018 Dec 17;
Nature biotechnology 2018 Dec 17;
Suppression of antitumor T cell immunity by the oncometabolite (R)-2-hydroxyglutarate.
Bunse L, Pusch S, Bunse T, Sahm F, Sanghvi K, Friedrich M, Alansary D, Sonner JK, Green E, Deumelandt K, Kilian M, Neftel C, Uhlig S, Kessler T, von Landenberg A, Berghoff AS, Marsh K, Steadman M, Zhu D, Nicolay B, Wiestler B, Breckwoldt MO, Al-Ali R, Karcher-Bausch S, Bozza M, Oezen I, Kramer M, Meyer J, Habel A, Eisel J, Poschet G, Weller M, Preusser M, Nadji-Ohl M, Thon N, Burger MC, Harter PN, Ratliff M, Harbottle R, Benner A, Schrimpf D, Okun J, Herold-Mende C, Turcan S, Kaulfuss S, Hess-Stumpp H, Bieback K, Cahill DP, Plate KH, Hänggi D, Dorsch M, Suvà ML, Niemeyer BA, von Deimling A, Wick W, Platten M
Nature medicine 2018 Aug;24(8):1192-1203
Nature medicine 2018 Aug;24(8):1192-1203
CMV-infected kidney grafts drive the expansion of blood-borne CMV-specific T cells restricted by shared class I HLA molecules via presentation on donor cells.
Gatault P, Al-Hajj S, Noble J, Chevallier E, Piollet M, Forconi C, Gaudy-Graffin C, Thibault G, Miquelestorena-Standley E, Halimi JM, Büchler M, Lemoine R, Baron C
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2018 Aug;18(8):1904-1913
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2018 Aug;18(8):1904-1913
Potential role of extracellular vesicle-mediated antigen presentation in Helicobacter pylori hypersensitivity during eradication therapy.
Ito T, Shiromizu T, Ohnishi S, Suzuki S, Mabe K, Hasegawa A, Ujiie H, Fujita Y, Sato Y, Terai S, Kato M, Asaka M, Tomonaga T, Shimizu H, Abe R
The Journal of allergy and clinical immunology 2018 Aug;142(2):672-676.e12
The Journal of allergy and clinical immunology 2018 Aug;142(2):672-676.e12
A Diverse Lipid Antigen-Specific TCR Repertoire Is Clonally Expanded during Active Tuberculosis.
DeWitt WS, Yu KKQ, Wilburn DB, Sherwood A, Vignali M, Day CL, Scriba TJ, Robins HS, Swanson WJ, Emerson RO, Bradley PH, Seshadri C
Journal of immunology (Baltimore, Md. : 1950) 2018 Aug 1;201(3):888-896
Journal of immunology (Baltimore, Md. : 1950) 2018 Aug 1;201(3):888-896
Epstein-Barr virus strain heterogeneity impairs human T-cell immunity.
Cirac A, Stützle S, Dieckmeyer M, Adhikary D, Moosmann A, Körber N, Bauer T, Witter K, Delecluse HJ, Behrends U, Mautner J
Cancer immunology, immunotherapy : CII 2018 Apr;67(4):663-674
Cancer immunology, immunotherapy : CII 2018 Apr;67(4):663-674
An Enzyme-Linked Immunosorbent Spot Assay Measuring Borrelia burgdorferi B31-Specific Interferon Gamma-Secreting T Cells Cannot Discriminate Active Lyme Neuroborreliosis from Past Lyme Borreliosis: a Prospective Study in the Netherlands.
van Gorkom T, Sankatsing SUC, Voet W, Ismail DM, Muilwijk RH, Salomons M, Vlaminckx BJM, Bossink AWJ, Notermans DW, Bouwman JJM, Kremer K, Thijsen SFT
Journal of clinical microbiology 2018 Apr;56(4)
Journal of clinical microbiology 2018 Apr;56(4)
WT1-pulsed Dendritic Cell Vaccine Combined with Chemotherapy for Resected Pancreatic Cancer in a Phase I Study.
Yanagisawa R, Koizumi T, Koya T, Sano K, Koido S, Nagai K, Kobayashi M, Okamoto M, Sugiyama H, Shimodaira S
Anticancer research 2018 Apr;38(4):2217-2225
Anticancer research 2018 Apr;38(4):2217-2225
Assessment of Humoral, Innate, and T-Cell Immune Responses to Adeno-Associated Virus Vectors.
Calcedo R, Chichester JA, Wilson JM
Human gene therapy methods 2018 Apr;29(2):86-95
Human gene therapy methods 2018 Apr;29(2):86-95
Adenovirus-specific T-lymphocyte efficacy in the presence of methylprednisolone: An in vitro study.
Campidelli A, Qian C, Laroye C, Decot V, Reppel L, D'aveni M, Bensoussan D
Cytotherapy 2018 Apr;20(4):524-531
Cytotherapy 2018 Apr;20(4):524-531
T cell autoreactivity directed toward CD1c itself rather than toward carried self lipids.
Wun KS, Reijneveld JF, Cheng TY, Ladell K, Uldrich AP, Le Nours J, Miners KL, McLaren JE, Grant EJ, Haigh OL, Watkins TS, Suliman S, Iwany S, Jimenez J, Calderon R, Tamara KL, Leon SR, Murray MB, Mayfield JA, Altman JD, Purcell AW, Miles JJ, Godfrey DI, Gras S, Price DA, Van Rhijn I, Moody DB, Rossjohn J
Nature immunology 2018 Apr;19(4):397-406
Nature immunology 2018 Apr;19(4):397-406
Prediction of improved survival in patients with pancreatic cancer via IL-21 enhanced detection of mesothelin epitope-reactive T-cell responses.
Meng Q, Valentini D, Rao M, Liu Z, Xie S, Morgell A, Dodoo E, Löhr M, Rangelova E, Del Chiaro M, Ernberg I, Maeurer M
Oncotarget 2018 Apr 27;9(32):22451-22459
Oncotarget 2018 Apr 27;9(32):22451-22459
Persistence of memory B-cell and T-cell responses to the quadrivalent HPV vaccine in HIV-infected children.
Weinberg A, Huang S, Moscicki AB, Saah A, Levin MJ, IMPAACT P1085 Protocol Team
AIDS (London, England) 2018 Apr 24;32(7):851-860
AIDS (London, England) 2018 Apr 24;32(7):851-860
Peptide mimic for influenza vaccination using nonnatural combinatorial chemistry.
Miles JJ, Tan MP, Dolton G, Edwards ES, Galloway SA, Laugel B, Clement M, Makinde J, Ladell K, Matthews KK, Watkins TS, Tungatt K, Wong Y, Lee HS, Clark RJ, Pentier JM, Attaf M, Lissina A, Ager A, Gallimore A, Rizkallah PJ, Gras S, Rossjohn J, Burrows SR, Cole DK, Price DA, Sewell AK
The Journal of clinical investigation 2018 Apr 2;128(4):1569-1580
The Journal of clinical investigation 2018 Apr 2;128(4):1569-1580
CD1b Tetramers Identify T Cells that Recognize Natural and Synthetic Diacylated Sulfoglycolipids from Mycobacterium tuberculosis.
James CA, Yu KKQ, Gilleron M, Prandi J, Yedulla VR, Moleda ZZ, Diamanti E, Khan M, Aggarwal VK, Reijneveld JF, Reinink P, Lenz S, Emerson RO, Scriba TJ, Souter MNT, Godfrey DI, Pellicci DG, Moody DB, Minnaard AJ, Seshadri C, Van Rhijn I
Cell chemical biology 2018 Apr 19;25(4):392-402.e14
Cell chemical biology 2018 Apr 19;25(4):392-402.e14
Impact of lenalidomide maintenance on the immune environment of multiple myeloma patients with low tumor burden after autologous stem cell transplantation.
Fostier K, Caers J, Meuleman N, Broos K, Corthals J, Thielemans K, Schots R, De Keersmaecker B
Oncotarget 2018 Apr 17;9(29):20476-20489
Oncotarget 2018 Apr 17;9(29):20476-20489
Direct-Acting Antiviral Prophylaxis in Kidney Transplantation From Hepatitis C Virus-Infected Donors to Noninfected Recipients: An Open-Label Nonrandomized Trial.
Durand CM, Bowring MG, Brown DM, Chattergoon MA, Massaccesi G, Bair N, Wesson R, Reyad A, Naqvi FF, Ostrander D, Sugarman J, Segev DL, Sulkowski M, Desai NM
Annals of internal medicine 2018 Apr 17;168(8):533-540
Annals of internal medicine 2018 Apr 17;168(8):533-540
Identification of neoepitopes recognized by tumor-infiltrating lymphocytes (TILs) from patients with glioma.
Valentini D, Rao M, Meng Q, von Landenberg A, Bartek J Jr, Sinclair G, Paraschoudi G, Jäger E, Harvey-Peredo I, Dodoo E, Maeurer M
Oncotarget 2018 Apr 13;9(28):19469-19480
Oncotarget 2018 Apr 13;9(28):19469-19480
Sustained Specific and Cross-Reactive T Cell Responses to Zika and Dengue Virus NS3 in West Africa.
Herrera BB, Tsai WY, Chang CA, Hamel DJ, Wang WK, Lu Y, Mboup S, Kanki PJ
Journal of virology 2018 Apr 1;92(7)
Journal of virology 2018 Apr 1;92(7)
Cancer-associated fibroblasts induce PDL1+ neutrophils through the IL6-STAT3 pathway that foster immune suppression in hepatocellular carcinoma.
Cheng Y, Li H, Deng Y, Tai Y, Zeng K, Zhang Y, Liu W, Zhang Q, Yang Y
Cell death & disease 2018 Apr 1;9(4):422
Cell death & disease 2018 Apr 1;9(4):422
Peptide-MHC Class I Tetramers Can Fail To Detect Relevant Functional T Cell Clonotypes and Underestimate Antigen-Reactive T Cell Populations.
Rius C, Attaf M, Tungatt K, Bianchi V, Legut M, Bovay A, Donia M, Thor Straten P, Peakman M, Svane IM, Ott S, Connor T, Szomolay B, Dolton G, Sewell AK
Journal of immunology (Baltimore, Md. : 1950) 2018 Apr 1;200(7):2263-2279
Journal of immunology (Baltimore, Md. : 1950) 2018 Apr 1;200(7):2263-2279
Latent Cytomegalovirus (CMV) Infection Does Not Detrimentally Alter T Cell Responses in the Healthy Old, But Increased Latent CMV Carriage Is Related to Expanded CMV-Specific T Cells.
Jackson SE, Sedikides GX, Okecha G, Poole EL, Sinclair JH, Wills MR
Frontiers in immunology 2017;8:733
Frontiers in immunology 2017;8:733
A Phase 1 Human Immunodeficiency Virus Vaccine Trial for Cross-Profiling the Kinetics of Serum and Mucosal Antibody Responses to CN54gp140 Modulated by Two Homologous Prime-Boost Vaccine Regimens.
Kratochvil S, McKay PF, Kopycinski JT, Bishop C, Hayes PJ, Muir L, Pinder CL, Cizmeci D, King D, Aldon Y, Wines BD, Hogarth PM, Chung AW, Kent SJ, Held K, Geldmacher C, Dally L, Santos NS, Cole T, Gilmour J, Fidler S, Shattock RJ
Frontiers in immunology 2017;8:595
Frontiers in immunology 2017;8:595
Preservation of Antigen-Specific Functions of αβ T Cells and B Cells Removed from Hematopoietic Stem Cell Transplants Suggests Their Use As an Alternative Cell Source for Advanced Manipulation and Adoptive Immunotherapy.
Li Pira G, Di Cecca S, Biagini S, Girolami E, Cicchetti E, Bertaina V, Quintarelli C, Caruana I, Lucarelli B, Merli P, Pagliara D, Brescia LP, Bertaina A, Montanari M, Locatelli F
Frontiers in immunology 2017;8:332
Frontiers in immunology 2017;8:332
Mucosal-Associated Invariant T Cells Display a Poor Reconstitution and Altered Phenotype after Allogeneic Hematopoietic Stem Cell Transplantation.
Solders M, Erkers T, Gorchs L, Poiret T, Remberger M, Magalhaes I, Kaipe H
Frontiers in immunology 2017;8:1861
Frontiers in immunology 2017;8:1861
Safety and Immunogenicity of Malaria Vectored Vaccines Given with Routine Expanded Program on Immunization Vaccines in Gambian Infants and Neonates: A Randomized Controlled Trial.
Mensah VA, Roetynck S, Kanteh EK, Bowyer G, Ndaw A, Oko F, Bliss CM, Jagne YJ, Cortese R, Nicosia A, Roberts R, D'Alessio F, Leroy O, Faye B, Kampmann B, Cisse B, Bojang K, Gerry S, Viebig NK, Lawrie AM, Clarke E, Imoukhuede EB, Ewer KJ, Hill AVS, Afolabi MO
Frontiers in immunology 2017;8:1551
Frontiers in immunology 2017;8:1551
Global Assessment of Dengue Virus-Specific CD4(+) T Cell Responses in Dengue-Endemic Areas.
Grifoni A, Angelo MA, Lopez B, O'Rourke PH, Sidney J, Cerpas C, Balmaseda A, Silveira CGT, Maestri A, Costa PR, Durbin AP, Diehl SA, Phillips E, Mallal S, De Silva AD, Nchinda G, Nkenfou C, Collins MH, de Silva AM, Lim MQ, Macary PA, Tatullo F, Solomon T, Satchidanandam V, Desai A, Ravi V, Coloma J, Turtle L, Rivino L, Kallas EG, Peters B, Harris E, Sette A, Weiskopf D
Frontiers in immunology 2017;8:1309
Frontiers in immunology 2017;8:1309
Intratumorally injected pro-inflammatory allogeneic dendritic cells as immune enhancers: a first-in-human study in unfavourable risk patients with metastatic renal cell carcinoma.
Laurell A, Lönnemark M, Brekkan E, Magnusson A, Tolf A, Wallgren AC, Andersson B, Adamson L, Kiessling R, Karlsson-Parra A
Journal for immunotherapy of cancer 2017;5:52
Journal for immunotherapy of cancer 2017;5:52
Indoleamine 2,3-dioxygenase and survivin peptide vaccine combined with temozolomide in metastatic melanoma.
Nitschke NJ, Bjoern J, Iversen TZ, Andersen MH, Svane IM
Stem cell investigation 2017;4:77
Stem cell investigation 2017;4:77
Sp17 Protein Expression and Major Histocompatibility Class I and II Epitope Presentation in Diffuse Large B Cell Lymphoma Patients.
Ait-Tahar K, Anderson AP, Barnardo M, Collins GP, Hatton CSR, Banham AH, Pulford K
Advances in hematology 2017;2017:6527306
Advances in hematology 2017;2017:6527306
Analysis of LC3-Associated Phagocytosis and Antigen Presentation.
Ligeon LA, Romao S, Münz C
Methods in molecular biology (Clifton, N.J.) 2017;1519:145-168
Methods in molecular biology (Clifton, N.J.) 2017;1519:145-168
Single-cell profiling of dynamic cytokine secretion and the phenotype of immune cells.
An X, Sendra VG, Liadi I, Ramesh B, Romain G, Haymaker C, Martinez-Paniagua M, Lu Y, Radvanyi LG, Roysam B, Varadarajan N
PloS one 2017;12(8):e0181904
PloS one 2017;12(8):e0181904
An aerosol challenge model of tuberculosis in Mauritian cynomolgus macaques.
Sharpe SA, White AD, Sibley L, Gleeson F, Hall GA, Basaraba RJ, McIntyre A, Clark SO, Gooch K, Marsh PD, Williams A, Dennis MJ
PloS one 2017;12(3):e0171906
PloS one 2017;12(3):e0171906
Comprehensive mapping of antigen specific T cell responses in hepatitis C virus infected patients with or without spontaneous viral clearance.
Zhang C, Hua R, Cui Y, Wang S, Yan H, Li D, Zhang Y, Tu Z, Hao P, Chen X, Zhong J, Niu J, Jin X
PloS one 2017;12(2):e0171217
PloS one 2017;12(2):e0171217
Immunodominant cytomegalovirus-specific CD8+ T-cell responses in sub-Saharan African populations.
Malik A, Adland E, Laker L, Kløverpris H, Fardoos R, Roider J, Severinsen MC, Chen F, Riddell L, Edwards A, Buus S, Jooste P, Matthews PC, Goulder PJR
PloS one 2017;12(12):e0189612
PloS one 2017;12(12):e0189612
CD1b-mycolic acid tetramers demonstrate T-cell fine specificity for mycobacterial lipid tails.
Van Rhijn I, Iwany SK, Fodran P, Cheng TY, Gapin L, Minnaard AJ, Moody DB
European journal of immunology 2017 Sep;47(9):1525-1534
European journal of immunology 2017 Sep;47(9):1525-1534
Influence of Transmitted Virus on the Host's Immune Response: A Case Study.
Merani S, Lucas M, Deshpande P, Pfafferott K, Chopra A, Cooper D, Leary S, Luciani F, Gaudieri S
Viral immunology 2017 Sep;30(7):533-541
Viral immunology 2017 Sep;30(7):533-541
Mesothelin-specific Immune Responses Predict Survival of Patients With Brain Metastasis.
Zhenjiang L, Rao M, Luo X, Sandberg E, Bartek J Jr, Schoutrop E, von Landenberg A, Meng Q, Valentini D, Poiret T, Sinclair G, Peredo IH, Dodoo E, Maeurer M
EBioMedicine 2017 Sep;23:20-24
EBioMedicine 2017 Sep;23:20-24
Strong interferon-gamma mediated cellular immunity to scrub typhus demonstrated using a novel whole cell antigen ELISpot assay in rhesus macaques and humans.
Sumonwiriya M, Paris DH, Sunyakumthorn P, Anantatat T, Jenjaroen K, Chumseng S, Im-Erbsin R, Tanganuchitcharnchai A, Jintaworn S, Blacksell SD, Chowdhury FR, Kronsteiner B, Teparrukkul P, Burke RL, Lombardini ED, Richards AL, Mason CJ, Jones JW, Day NPJ, Dunachie SJ
PLoS neglected tropical diseases 2017 Sep;11(9):e0005846
PLoS neglected tropical diseases 2017 Sep;11(9):e0005846
Flavonolignans Inhibit IL1-β-Induced Cross-Talk between Blood Platelets and Leukocytes.
Bijak M, Dziedzic A, Synowiec E, Sliwinski T, Saluk-Bijak J
Nutrients 2017 Sep 15;9(9)
Nutrients 2017 Sep 15;9(9)
A synthetic human cytomegalovirus pp65-IE1 fusion antigen efficiently induces and expands virus specific T cells.
Link EK, Brandmüller C, Suezer Y, Ameres S, Volz A, Moosmann A, Sutter G, Lehmann MH
Vaccine 2017 Sep 12;35(38):5131-5139
Vaccine 2017 Sep 12;35(38):5131-5139
Adaptive from Innate: Human IFN-γ(+)CD4(+) T Cells Can Arise Directly from CXCL8-Producing Recent Thymic Emigrants in Babies and Adults.
Das A, Rouault-Pierre K, Kamdar S, Gomez-Tourino I, Wood K, Donaldson I, Mein CA, Bonnet D, Hayday AC, Gibbons DL
Journal of immunology (Baltimore, Md. : 1950) 2017 Sep 1;199(5):1696-1705
Journal of immunology (Baltimore, Md. : 1950) 2017 Sep 1;199(5):1696-1705
Enhanced stimulation of human tumor-specific T cells by dendritic cells matured in the presence of interferon-γ and multiple toll-like receptor agonists.
Lövgren T, Sarhan D, Truxová I, Choudhary B, Maas R, Melief J, Nyström M, Edbäck U, Vermeij R, Scurti G, Nishimura M, Masucci G, Karlsson-Parra A, Lundqvist A, Adamson L, Kiessling R
Cancer immunology, immunotherapy : CII 2017 Oct;66(10):1333-1344
Cancer immunology, immunotherapy : CII 2017 Oct;66(10):1333-1344
Circulating follicular helper T cells presented distinctively different responses toward bacterial antigens in primary biliary cholangitis.
Zhou ZQ, Tong DN, Guan J, Li MF, Feng QM, Zhou MJ, Zhang ZY
International immunopharmacology 2017 Oct;51:76-81
International immunopharmacology 2017 Oct;51:76-81
Remnant Epitope Autoimmunity in Human Abdominal Aortic Aneurysm: A Pilot Study with Elastin Peptides.
Verhoeven J, Lambrecht A, Verbrugghe P, Herijgers P, Fourneau I
Annals of vascular surgery 2017 Oct;44:408-413
Annals of vascular surgery 2017 Oct;44:408-413
T-cell regulation through a basic suppressive mechanism targeting low-density lipoprotein receptor-related protein 1.
Panezai J, Bergdahl E, Sundqvist KG
Immunology 2017 Oct;152(2):308-327
Immunology 2017 Oct;152(2):308-327
Tetanus Toxoid carrier protein induced T-helper cell responses upon vaccination of middle-aged adults.
van der Heiden M, Duizendstra A, Berbers GAM, Boots AMH, Buisman AM
Vaccine 2017 Oct 9;35(42):5581-5588
Vaccine 2017 Oct 9;35(42):5581-5588
Gastric expression of IL-17A and IFNγ in Helicobacter pylori infected individuals is related to symptoms.
Adamsson J, Ottsjö LS, Lundin SB, Svennerholm AM, Raghavan S
Cytokine 2017 Nov;99:30-34
Cytokine 2017 Nov;99:30-34
Genome editing for scalable production of alloantigen-free lentiviral vectors for in vivo gene therapy.
Milani M, Annoni A, Bartolaccini S, Biffi M, Russo F, Di Tomaso T, Raimondi A, Lengler J, Holmes MC, Scheiflinger F, Lombardo A, Cantore A, Naldini L
EMBO molecular medicine 2017 Nov;9(11):1558-1573
EMBO molecular medicine 2017 Nov;9(11):1558-1573
Artificial human antigen-presenting cells are superior to dendritic cells at inducing cytotoxic T-cell responses.
Li H, Shao S, Cai J, Burner D, Lu L, Chen Q, Minev B, Ma W
Immunology 2017 Nov;152(3):462-471
Immunology 2017 Nov;152(3):462-471
Interleukin 10 enhanced CD8+ T cell activity and reduced CD8(+) T cell apoptosis in patients with diffuse large B cell lymphoma.
Qiu H, Hu X, Gao L, Chen L, Chen J, Yuan J, Huang C, Xu X, Yang J
Experimental cell research 2017 Nov 15;360(2):146-152
Experimental cell research 2017 Nov 15;360(2):146-152
Low-Dose Cyclophosphamide Induces Antitumor T-Cell Responses, which Associate with Survival in Metastatic Colorectal Cancer.
Scurr M, Pembroke T, Bloom A, Roberts D, Thomson A, Smart K, Bridgeman H, Adams R, Brewster A, Jones R, Gwynne S, Blount D, Harrop R, Hills R, Gallimore A, Godkin A
Clinical cancer research : an official journal of the American Association for Cancer Research 2017 Nov 15;23(22):6771-6780
Clinical cancer research : an official journal of the American Association for Cancer Research 2017 Nov 15;23(22):6771-6780
DNA Vaccination by Electroporation Amplifies Broadly Cross-Restricted Public TCR Clonotypes Shared with HIV Controllers.
Mukhopadhyay M, Galperin M, Patgaonkar M, Vasan S, Ho DD, Nouël A, Claireaux M, Benati D, Lambotte O, Huang Y, Chakrabarti LA
Journal of immunology (Baltimore, Md. : 1950) 2017 Nov 15;199(10):3437-3452
Journal of immunology (Baltimore, Md. : 1950) 2017 Nov 15;199(10):3437-3452
Cytomegalovirus (CMV) Epitope-Specific CD4(+) T Cells Are Inflated in HIV(+) CMV(+) Subjects.
Abana CO, Pilkinton MA, Gaudieri S, Chopra A, McDonnell WJ, Wanjalla C, Barnett L, Gangula R, Hager C, Jung DK, Engelhardt BG, Jagasia MH, Klenerman P, Phillips EJ, Koelle DM, Kalams SA, Mallal SA
Journal of immunology (Baltimore, Md. : 1950) 2017 Nov 1;199(9):3187-3201
Journal of immunology (Baltimore, Md. : 1950) 2017 Nov 1;199(9):3187-3201
Multiple therapeutic peptide vaccines for patients with advanced gastric cancer.
Fujiwara Y, Okada K, Omori T, Sugimura K, Miyata H, Ohue M, Kobayashi S, Takahashi H, Nakano H, Mochizuki C, Shimizu K, Yano M, Nakamura Y, Mori M, Doki Y
International journal of oncology 2017 May;50(5):1655-1662
International journal of oncology 2017 May;50(5):1655-1662
Human papillomavirus 16 (HPV16) and HPV52 E6-specific immunity in HIV-infected adults on combination antiretroviral therapy.
Leng CY, Low HC, Chua LL, Chong ML, Sulaiman H, Azwa I, Roberts JM, Kamarulzaman A, Rajasuriar R, Woo YL
HIV medicine 2017 May;18(5):321-331
HIV medicine 2017 May;18(5):321-331
Boosting of post-exposure human T-cell and B-cell recall responses in vivo by Burkholderia pseudomallei-related proteins.
Nithichanon A, Gourlay LJ, Bancroft GJ, Ato M, Takahashi Y, Lertmemongkolchai G
Immunology 2017 May;151(1):98-109
Immunology 2017 May;151(1):98-109
Antigen delivery to dendritic cells shapes human CD4+ and CD8+ T cell memory responses to Staphylococcus aureus.
Uebele J, Stein C, Nguyen MT, Schneider A, Kleinert F, Tichá O, Bierbaum G, Götz F, Bekeredjian-Ding I
PLoS pathogens 2017 May;13(5):e1006387
PLoS pathogens 2017 May;13(5):e1006387
The effect of current Schistosoma mansoni infection on the immunogenicity of a candidate TB vaccine, MVA85A, in BCG-vaccinated adolescents: An open-label trial.
Wajja A, Kizito D, Nassanga B, Nalwoga A, Kabagenyi J, Kimuda S, Galiwango R, Mutonyi G, Vermaak S, Satti I, Verweij J, Tukahebwa E, Cose S, Levin J, Kaleebu P, Elliott AM, McShane H
PLoS neglected tropical diseases 2017 May;11(5):e0005440
PLoS neglected tropical diseases 2017 May;11(5):e0005440
Smoking reduces circulating CD26(hi)CD161(hi) MAIT cells in healthy individuals and patients with multiple sclerosis.
Ammitzbøll C, Börnsen L, Romme Christensen J, Ratzer R, Romme Nielsen B, Søndergaard HB, von Essen MR, Sellebjerg F
Journal of leukocyte biology 2017 May;101(5):1211-1220
Journal of leukocyte biology 2017 May;101(5):1211-1220
Exploration of Biomarkers for Amoxicillin/Clavulanate-Induced Liver Injury: Multi-Omics Approaches.
Lee J, Ji SC, Kim B, Yi S, Shin KH, Cho JY, Lim KS, Lee SH, Yoon SH, Chung JY, Yu KS, Park HS, Kim SH, Jang IJ
Clinical and translational science 2017 May;10(3):163-171
Clinical and translational science 2017 May;10(3):163-171
Drug-specific upregulation of CD137 on CD8+ T cells aids in the diagnosis of multiple antibiotic toxic epidermal necrolysis.
Trubiano JA, Redwood A, Strautins K, Pavlos R, Woolnough E, Chang CC, Phillips E
The journal of allergy and clinical immunology. In practice 2017 May-Jun;5(3):823-826
The journal of allergy and clinical immunology. In practice 2017 May-Jun;5(3):823-826
Varicella vaccination elicits a humoral and cellular response in children with rheumatic diseases using immune suppressive treatment.
Groot N, Pileggi G, Sandoval CB, Grein I, Berbers G, Ferriani VPL, Wulffraat N, de Roock S
Vaccine 2017 May 15;35(21):2818-2822
Vaccine 2017 May 15;35(21):2818-2822
Boosting of Cross-Reactive and Protection-Associated T Cells in Children After Live Attenuated Influenza Vaccination.
Mohn KGI, Zhou F, Brokstad KA, Sridhar S, Cox RJ
The Journal of infectious diseases 2017 May 15;215(10):1527-1535
The Journal of infectious diseases 2017 May 15;215(10):1527-1535
A phase II trial of autologous dendritic cell vaccination and radiochemotherapy following fluorescence-guided surgery in newly diagnosed glioblastoma patients.
Inogés S, Tejada S, de Cerio AL, Gállego Pérez-Larraya J, Espinós J, Idoate MA, Domínguez PD, de Eulate RG, Aristu J, Bendandi M, Pastor F, Alonso M, Andreu E, Cardoso FP, Valle RD
Journal of translational medicine 2017 May 12;15(1):104
Journal of translational medicine 2017 May 12;15(1):104
Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells.
Ooi JD, Petersen J, Tan YH, Huynh M, Willett ZJ, Ramarathinam SH, Eggenhuizen PJ, Loh KL, Watson KA, Gan PY, Alikhan MA, Dudek NL, Handel A, Hudson BG, Fugger L, Power DA, Holt SG, Coates PT, Gregersen JW, Purcell AW, Holdsworth SR, La Gruta NL, Reid HH, Rossjohn J, Kitching AR
Nature 2017 May 11;545(7653):243-247
Nature 2017 May 11;545(7653):243-247
Assessment of the Plasmodium falciparum Preerythrocytic Antigen UIS3 as a Potential Candidate for a Malaria Vaccine.
Longley RJ, Halbroth BR, Salman AM, Ewer KJ, Hodgson SH, Janse CJ, Khan SM, Hill AVS, Spencer AJ
Infection and immunity 2017 Mar;85(3)
Infection and immunity 2017 Mar;85(3)
Polymorphism in programmed cell death 1 gene is strongly associated with lung and kidney allograft survival in recipients from CMV-positive donors.
Forconi C, Gatault P, Miquelestorena-Standley E, Noble J, Al-Hajj S, Guillemain R, Stern M, Hoffmann T, Prat L, Suberbielle C, Masson E, Cesbron-Gautier A, Gaudy-Graffin C, Goudeau A, Thibault G, Ivanes F, Guibon R, Kazma I, Lebranchu Y, Büchler M, Magnan A, Halimi JM, Baron C
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2017 Mar;36(3):315-324
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2017 Mar;36(3):315-324
Evaluation of the efficacy of a therapeutic HIV vaccine by in vitro stimulation assay.
He X, Wang W, Xu K, Feng X, Zeng Y
Cellular immunology 2017 Mar;313:67-71
Cellular immunology 2017 Mar;313:67-71
Microwave-based treatments of wheat kernels do not abolish gluten epitopes implicated in celiac disease.
Gianfrani C, Mamone G, la Gatta B, Camarca A, Di Stasio L, Maurano F, Picascia S, Capozzi V, Perna G, Picariello G, Di Luccia A
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2017 Mar;101:105-113
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2017 Mar;101:105-113
An optimized IFN-γ ELISpot assay for the sensitive and standardized monitoring of CMV protein-reactive effector cells of cell-mediated immunity.
Barabas S, Spindler T, Kiener R, Tonar C, Lugner T, Batzilla J, Bendfeldt H, Rascle A, Asbach B, Wagner R, Deml L
BMC immunology 2017 Mar 7;18(1):14
BMC immunology 2017 Mar 7;18(1):14
The therapeutic HIV Env C5/gp41 vaccine candidate Vacc-C5 induces specific T cell regulation in a phase I/II clinical study.
Brekke K, Sommerfelt M, Ökvist M, Dyrhol-Riise AM, Kvale D
BMC infectious diseases 2017 Mar 24;17(1):228
BMC infectious diseases 2017 Mar 24;17(1):228
Human Cytomegalovirus (HCMV)-Specific CD4(+) T Cells Are Polyfunctional and Can Respond to HCMV-Infected Dendritic Cells In Vitro.
Jackson SE, Sedikides GX, Mason GM, Okecha G, Wills MR
Journal of virology 2017 Mar 15;91(6)
Journal of virology 2017 Mar 15;91(6)
Human CD4(+) T Cell Responses to an Attenuated Tetravalent Dengue Vaccine Parallel Those Induced by Natural Infection in Magnitude, HLA Restriction, and Antigen Specificity.
Angelo MA, Grifoni A, O'Rourke PH, Sidney J, Paul S, Peters B, de Silva AD, Phillips E, Mallal S, Diehl SA, Kirkpatrick BD, Whitehead SS, Durbin AP, Sette A, Weiskopf D
Journal of virology 2017 Mar 1;91(5)
Journal of virology 2017 Mar 1;91(5)
IFNγ enhances cytotoxic efficiency of the cytotoxic T lymphocytes against human glioma cells.
Shao S, Risch E, Burner D, Lu L, Minev B, Ma W
International immunopharmacology 2017 Jun;47:159-165
International immunopharmacology 2017 Jun;47:159-165
Human Effector Memory T Helper Cells Engage with Mouse Macrophages and Cause Graft-versus-Host-Like Pathology in Skin of Humanized Mice Used in a Nonclinical Immunization Study.
Sundarasetty B, Volk V, Theobald SJ, Rittinghausen S, Schaudien D, Neuhaus V, Figueiredo C, Schneider A, Gerasch L, Mucci A, Moritz T, von Kaisenberg C, Spineli LM, Sewald K, Braun A, Weigt H, Ganser A, Stripecke R
The American journal of pathology 2017 Jun;187(6):1380-1398
The American journal of pathology 2017 Jun;187(6):1380-1398
Therapeutic protein deimmunization by T-cell epitope removal: antigen-specific immune responses in vitro and in vivo.
Asgari S, Ebrahim-Habibi A, Mahdavi M, Choopani M, Mirzahoseini H
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2017 Jun;125(6):544-552
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2017 Jun;125(6):544-552
Pyruvate controls the checkpoint inhibitor PD-L1 and suppresses T cell immunity.
Watanabe R, Shirai T, Namkoong H, Zhang H, Berry GJ, Wallis BB, Schaefgen B, Harrison DG, Tremmel JA, Giacomini JC, Goronzy JJ, Weyand CM
The Journal of clinical investigation 2017 Jun 30;127(7):2725-2738
The Journal of clinical investigation 2017 Jun 30;127(7):2725-2738
Specific humoral and cellular immune responses in cancer patients undergoing chronic immunization with a VEGF-based therapeutic vaccine.
Morera Y, Sánchez J, Bequet-Romero M, Selman-Housein KH, de la Torre A, Hernández-Bernal F, Martín Y, Garabito A, Piñero J, Bermúdez C, de la Torre J, Ayala M, Gavilondo JV
Vaccine 2017 Jun 16;35(28):3582-3590
Vaccine 2017 Jun 16;35(28):3582-3590
Spontaneous CD4(+) and CD8(+) T-cell responses directed against cancer testis antigens are present in the peripheral blood of testicular cancer patients.
Pearce H, Hutton P, Chaudhri S, Porfiri E, Patel P, Viney R, Moss P
European journal of immunology 2017 Jul;47(7):1232-1242
European journal of immunology 2017 Jul;47(7):1232-1242
Characterization of High-Avidity Cytomegalovirus-Specific T Cells with Differential Tetramer Binding Coappearing after Allogeneic Stem Cell Transplantation.
Ogonek J, Verma K, Schultze-Florey C, Varanasi P, Luther S, Schweier P, Kühnau W, Göhring G, Dammann E, Stadler M, Ganser A, Koehl U, Koenecke C, Weissinger EM, Hambach L
Journal of immunology (Baltimore, Md. : 1950) 2017 Jul 15;199(2):792-805
Journal of immunology (Baltimore, Md. : 1950) 2017 Jul 15;199(2):792-805
Epstein-Barr virus-specific adoptive immunotherapy for recurrent, metastatic nasopharyngeal carcinoma.
Huang J, Fogg M, Wirth LJ, Daley H, Ritz J, Posner MR, Wang FC, Lorch JH
Cancer 2017 Jul 15;123(14):2642-2650
Cancer 2017 Jul 15;123(14):2642-2650
Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer.
Sahin U, Derhovanessian E, Miller M, Kloke BP, Simon P, Löwer M, Bukur V, Tadmor AD, Luxemburger U, Schrörs B, Omokoko T, Vormehr M, Albrecht C, Paruzynski A, Kuhn AN, Buck J, Heesch S, Schreeb KH, Müller F, Ortseifer I, Vogler I, Godehardt E, Attig S, Rae R, Breitkreuz A, Tolliver C, Suchan M, Martic G, Hohberger A, Sorn P, Diekmann J, Ciesla J, Waksmann O, Brück AK, Witt M, Zillgen M, Rothermel A, Kasemann B, Langer D, Bolte S, Diken M, Kreiter S, Nemecek R, Gebhardt C, Grabbe S, Höller C, Utikal J, Huber C, Loquai C, Türeci Ö
Nature 2017 Jul 13;547(7662):222-226
Nature 2017 Jul 13;547(7662):222-226
An immunogenic personal neoantigen vaccine for patients with melanoma.
Ott PA, Hu Z, Keskin DB, Shukla SA, Sun J, Bozym DJ, Zhang W, Luoma A, Giobbie-Hurder A, Peter L, Chen C, Olive O, Carter TA, Li S, Lieb DJ, Eisenhaure T, Gjini E, Stevens J, Lane WJ, Javeri I, Nellaiappan K, Salazar AM, Daley H, Seaman M, Buchbinder EI, Yoon CH, Harden M, Lennon N, Gabriel S, Rodig SJ, Barouch DH, Aster JC, Getz G, Wucherpfennig K, Neuberg D, Ritz J, Lander ES, Fritsch EF, Hacohen N, Wu CJ
Nature 2017 Jul 13;547(7662):217-221
Nature 2017 Jul 13;547(7662):217-221
Dual non-contiguous peptide occupancy of HLA class I evoke antiviral human CD8 T cell response and form neo-epitopes with self-antigens.
Xiao Z, Ye Z, Tadwal VS, Shen M, Ren EC
Scientific reports 2017 Jul 11;7(1):5072
Scientific reports 2017 Jul 11;7(1):5072
Expression of CD14, IL10, and Tolerogenic Signature in Dendritic Cells Inversely Correlate with Clinical and Immunologic Response to TARP Vaccination in Prostate Cancer Patients.
Castiello L, Sabatino M, Ren J, Terabe M, Khuu H, Wood LV, Berzofsky JA, Stroncek DF
Clinical cancer research : an official journal of the American Association for Cancer Research 2017 Jul 1;23(13):3352-3364
Clinical cancer research : an official journal of the American Association for Cancer Research 2017 Jul 1;23(13):3352-3364
Immunogenicity of tocilizumab in patients with rheumatoid arthritis.
Sigaux J, Hamze M, Daien C, Morel J, Krzysiek R, Pallardy M, Maillere B, Mariette X, Miceli-Richard C
Joint bone spine 2017 Jan;84(1):39-45
Joint bone spine 2017 Jan;84(1):39-45
Immunological consequences of immunization with tumor lysate vaccine and propranolol as an adjuvant: A study on cytokine profiles in breast tumor microenvironment.
Ashrafi S, Shapouri R, Mahdavi M
Immunology letters 2017 Jan;181:63-70
Immunology letters 2017 Jan;181:63-70
Safety and immunogenicity of a live attenuated pentavalent rotavirus vaccine in HIV-exposed infants with or without HIV infection in Africa.
Levin MJ, Lindsey JC, Kaplan SS, Schimana W, Lawrence J, McNeal MM, Bwakura-Dangarembizi M, Ogwu A, Mpabalwani EM, Sato P, Siberry G, Nelson M, Hille D, Weinberg GA, Weinberg A
AIDS (London, England) 2017 Jan 2;31(1):49-59
AIDS (London, England) 2017 Jan 2;31(1):49-59
Protection against Plasmodium falciparum malaria by PfSPZ Vaccine.
Epstein JE, Paolino KM, Richie TL, Sedegah M, Singer A, Ruben AJ, Chakravarty S, Stafford A, Ruck RC, Eappen AG, Li T, Billingsley PF, Manoj A, Silva JC, Moser K, Nielsen R, Tosh D, Cicatelli S, Ganeshan H, Case J, Padilla D, Davidson S, Garver L, Saverino E, Murshedkar T, Gunasekera A, Twomey PS, Reyes S, Moon JE, James ER, Kc N, Li M, Abot E, Belmonte A, Hauns K, Belmonte M, Huang J, Vasquez C, Remich S, Carrington M, Abebe Y, Tillman A, Hickey B, Regules J, Villasante E, Sim BKL, Hoffman SL
JCI insight 2017 Jan 12;2(1):e89154
JCI insight 2017 Jan 12;2(1):e89154
Towards standardized automated immunomonitoring: an automated ELISpot assay for safe and parallelized functionality analysis of immune cells.
Neubauer JC, Sébastien I, Germann A, Müller SC, Meyerhans A, von Briesen H, Zimmermann H
Cytotechnology 2017 Feb;69(1):57-73
Cytotechnology 2017 Feb;69(1):57-73
Systematic evaluation of monoclonal antibodies and immunoassays for the detection of Interferon-γ and Interleukin-2 in old and new world non-human primates.
Höglind A, Areström I, Ehrnfelt C, Masjedi K, Zuber B, Giavedoni L, Ahlborg N
Journal of immunological methods 2017 Feb;441:39-48
Journal of immunological methods 2017 Feb;441:39-48
Safety and Immunogenicity of the Recombinant Mycobacterium bovis BCG Vaccine VPM1002 in HIV-Unexposed Newborn Infants in South Africa.
Loxton AG, Knaul JK, Grode L, Gutschmidt A, Meller C, Eisele B, Johnstone H, van der Spuy G, Maertzdorf J, Kaufmann SHE, Hesseling AC, Walzl G, Cotton MF
Clinical and vaccine immunology : CVI 2017 Feb;24(2)
Clinical and vaccine immunology : CVI 2017 Feb;24(2)
Expression of specific inflammasome gene modules stratifies older individuals into two extreme clinical and immunological states.
Furman D, Chang J, Lartigue L, Bolen CR, Haddad F, Gaudilliere B, Ganio EA, Fragiadakis GK, Spitzer MH, Douchet I, Daburon S, Moreau JF, Nolan GP, Blanco P, Déchanet-Merville J, Dekker CL, Jojic V, Kuo CJ, Davis MM, Faustin B
Nature medicine 2017 Feb;23(2):174-184
Nature medicine 2017 Feb;23(2):174-184
Hepatic carcinoma-associated fibroblasts enhance immune suppression by facilitating the generation of myeloid-derived suppressor cells.
Deng Y, Cheng J, Fu B, Liu W, Chen G, Zhang Q, Yang Y
Oncogene 2017 Feb 23;36(8):1090-1101
Oncogene 2017 Feb 23;36(8):1090-1101
Accumulation of Pol Mutations Selected by HLA-B*52:01-C*12:02 Protective Haplotype-Restricted Cytotoxic T Lymphocytes Causes Low Plasma Viral Load Due to Low Viral Fitness of Mutant Viruses.
Murakoshi H, Koyanagi M, Chikata T, Rahman MA, Kuse N, Sakai K, Gatanaga H, Oka S, Takiguchi M
Journal of virology 2017 Feb 15;91(4)
Journal of virology 2017 Feb 15;91(4)
Phase II clinical trial using novel peptide cocktail vaccine as a postoperative adjuvant treatment for surgically resected pancreatic cancer patients.
Miyazawa M, Katsuda M, Maguchi H, Katanuma A, Ishii H, Ozaka M, Yamao K, Imaoka H, Kawai M, Hirono S, Okada KI, Yamaue H
International journal of cancer 2017 Feb 15;140(4):973-982
International journal of cancer 2017 Feb 15;140(4):973-982
Study on age-dependent pre-existing 2009 pandemic influenza virus T and B cell responses from Chinese population.
Lv J, Ren ZY, Zhang YY, Liu YE, Gao J, Yao K, Feng D, Li ZY, Feng X, Liu YX, Jia N
BMC infectious diseases 2017 Feb 10;17(1):136
BMC infectious diseases 2017 Feb 10;17(1):136
The state of T cells before cryopreservation: Effects on post-thaw proliferation and function.
Luo Y, Wang P, Liu H, Zhu Z, Li C, Gao Y
Cryobiology 2017 Dec;79:65-70
Cryobiology 2017 Dec;79:65-70
Circulating gluten-specific FOXP3(+)CD39(+) regulatory T cells have impaired suppressive function in patients with celiac disease.
Cook L, Munier CML, Seddiki N, van Bockel D, Ontiveros N, Hardy MY, Gillies JK, Levings MK, Reid HH, Petersen J, Rossjohn J, Anderson RP, Zaunders JJ, Tye-Din JA, Kelleher AD
The Journal of allergy and clinical immunology 2017 Dec;140(6):1592-1603.e8
The Journal of allergy and clinical immunology 2017 Dec;140(6):1592-1603.e8
Long-lived CD8+ T cell responses following Crimean-Congo haemorrhagic fever virus infection.
Goedhals D, Paweska JT, Burt FJ
PLoS neglected tropical diseases 2017 Dec;11(12):e0006149
PLoS neglected tropical diseases 2017 Dec;11(12):e0006149
Ontogeny of the B- and T-cell response in a primary Zika virus infection of a dengue-naïve individual during the 2016 outbreak in Miami, FL.
Ricciardi MJ, Magnani DM, Grifoni A, Kwon YC, Gutman MJ, Grubaugh ND, Gangavarapu K, Sharkey M, Silveira CGT, Bailey VK, Pedreño-Lopez N, Gonzalez-Nieto L, Maxwell HS, Domingues A, Martins MA, Pham J, Weiskopf D, Altman J, Kallas EG, Andersen KG, Stevenson M, Lichtenberger P, Choe H, Whitehead SS, Sette A, Watkins DI
PLoS neglected tropical diseases 2017 Dec;11(12):e0006000
PLoS neglected tropical diseases 2017 Dec;11(12):e0006000
CD1a presentation of endogenous antigens by group 2 innate lymphoid cells.
Hardman CS, Chen YL, Salimi M, Jarrett R, Johnson D, Järvinen VJ, Owens RJ, Repapi E, Cousins DJ, Barlow JL, McKenzie ANJ, Ogg G
Science immunology 2017 Dec 22;2(18)
Science immunology 2017 Dec 22;2(18)
Prior Dengue Virus Exposure Shapes T Cell Immunity to Zika Virus in Humans.
Grifoni A, Pham J, Sidney J, O'Rourke PH, Paul S, Peters B, Martini SR, de Silva AD, Ricciardi MJ, Magnani DM, Silveira CGT, Maestri A, Costa PR, de-Oliveira-Pinto LM, de Azeredo EL, Damasco PV, Phillips E, Mallal S, de Silva AM, Collins M, Durbin A, Diehl SA, Cerpas C, Balmaseda A, Kuan G, Coloma J, Harris E, Crowe JE Jr, Stone M, Norris PJ, Busch M, Vivanco-Cid H, Cox J, Graham BS, Ledgerwood JE, Turtle L, Solomon T, Kallas EG, Watkins DI, Weiskopf D, Sette A
Journal of virology 2017 Dec 15;91(24)
Journal of virology 2017 Dec 15;91(24)
T-cell responses to KSHV infection: a systematic approach.
Roshan R, Labo N, Trivett M, Miley W, Marshall V, Coren L, Cornejo Castro EM, Perez H, Holdridge B, Davis E, Matus-Nicodemos R, Ayala VI, Sowder R 2nd, Wyvill KM, Aleman K, Fennessey C, Lifson J, Polizzotto MN, Douek D, Keele B, Uldrick TS, Yarchoan R, Ohlen C, Ott D, Whitby D
Oncotarget 2017 Dec 12;8(65):109402-109416
Oncotarget 2017 Dec 12;8(65):109402-109416
Control of HIV-1 by an HLA-B*52:01-C*12:02 Protective Haplotype.
Chikata T, Murakoshi H, Koyanagi M, Honda K, Gatanaga H, Oka S, Takiguchi M
The Journal of infectious diseases 2017 Dec 12;216(11):1415-1424
The Journal of infectious diseases 2017 Dec 12;216(11):1415-1424
Parity improves anti-tumor immunity in breast cancer patients.
Krause AL, Schuetz F, Boudewijns M, Pritsch M, Wallwiener M, Golatta M, Rom J, Heil J, Sohn C, Schneeweiss A, Beckhove P, Domschke C
Oncotarget 2017 Dec 1;8(62):104981-104991
Oncotarget 2017 Dec 1;8(62):104981-104991
Three-Year Durability of Immune Responses Induced by HIV-DNA and HIV-Modified Vaccinia Virus Ankara and Effect of a Late HIV-Modified Vaccinia Virus Ankara Boost in Tanzanian Volunteers.
Joachim A, Munseri PJ, Nilsson C, Bakari M, Aboud S, Lyamuya EF, Tecleab T, Liakina V, Scarlatti G, Robb ML, Earl PL, Moss B, Wahren B, Mhalu F, Ferrari G, Sandstrom E, Biberfeld G
AIDS research and human retroviruses 2017 Aug;33(8):880-888
AIDS research and human retroviruses 2017 Aug;33(8):880-888
Anti-HERV-K (HML-2) capsid antibody responses in HIV elite controllers.
de Mulder M, SenGupta D, Deeks SG, Martin JN, Pilcher CD, Hecht FM, Sacha JB, Nixon DF, Michaud HA
Retrovirology 2017 Aug 22;14(1):41
Retrovirology 2017 Aug 22;14(1):41
Intratumoral injection of IFN-β induces chemokine production in melanoma and augments the therapeutic efficacy of anti-PD-L1 mAb.
Uehara J, Ohkuri T, Kosaka A, Ishibashi K, Hirata Y, Ohara K, Nagato T, Oikawa K, Aoki N, Harabuchi Y, Ishida-Yamamoto A, Kobayashi H
Biochemical and biophysical research communications 2017 Aug 19;490(2):521-527
Biochemical and biophysical research communications 2017 Aug 19;490(2):521-527
Identification of Interleukin-27 (IL-27)/IL-27 Receptor Subunit Alpha as a Critical Immune Axis for In Vivo HIV Control.
Ruiz-Riol M, Berdnik D, Llano A, Mothe B, Gálvez C, Pérez-Álvarez S, Oriol-Tordera B, Olvera A, Silva-Arrieta S, Meulbroek M, Pujol F, Coll J, Martinez-Picado J, Ganoza C, Sanchez J, Gómez G, Wyss-Coray T, Brander C
Journal of virology 2017 Aug 15;91(16)
Journal of virology 2017 Aug 15;91(16)
Identification of Mycobacterial RplJ/L10 and RpsA/S1 Proteins as Novel Targets for CD4(+) T Cells.
Johnson AJ, Kennedy SC, Lindestam Arlehamn CS, Goldberg MF, Saini NK, Xu J, Paul S, Hegde SS, Blanchard JS, Chan J, Jacobs WR Jr, Sette A, Porcelli SA
Infection and immunity 2017 Apr;85(4)
Infection and immunity 2017 Apr;85(4)
Presentation of a Conserved Adenoviral Epitope on HLA-C*0702 Allows Evasion of Natural Killer but Not T Cell Responses.
Keib A, Günther PS, Faist B, Halenius A, Busch DH, Neuenhahn M, Jahn G, Dennehy KM
Viral immunology 2017 Apr;30(3):149-156
Viral immunology 2017 Apr;30(3):149-156
Anti-HER2 CD4(+) T-Helper Type 1 Immune Response is Superior to Breast MRI for Assessing Response to Neoadjuvant Therapy in Patients with HER2-Positive Breast Cancer.
De La Cruz LM, McDonald ES, Mick R, Datta J, Nocera NF, Xu S, Fisher CS, Czerniecki BJ
Annals of surgical oncology 2017 Apr;24(4):1057-1063
Annals of surgical oncology 2017 Apr;24(4):1057-1063
Immune reactivity after adenoviral-mediated aquaporin-1 cDNA transfer to human parotid glands.
Alevizos I, Zheng C, Cotrim AP, Goldsmith CM, McCullagh L, Berkowitz T, Strobl SL, Malyguine A, Kopp WC, Chiorini JA, Nikolov NP, Neely M, Illei GG, Baum BJ
Oral diseases 2017 Apr;23(3):337-346
Oral diseases 2017 Apr;23(3):337-346
Dendritic cell vaccination in combination with docetaxel for patients with metastatic castration-resistant prostate cancer: A randomized phase II study.
Kongsted P, Borch TH, Ellebaek E, Iversen TZ, Andersen R, Met Ö, Hansen M, Lindberg H, Sengeløv L, Svane IM
Cytotherapy 2017 Apr;19(4):500-513
Cytotherapy 2017 Apr;19(4):500-513
M1-like monocytes are a major immunological determinant of severity in previously healthy adults with life-threatening influenza.
Cole SL, Dunning J, Kok WL, Benam KH, Benlahrech A, Repapi E, Martinez FO, Drumright L, Powell TJ, Bennett M, Elderfield R, Thomas C, MOSAIC investigators, Dong T, McCauley J, Liew FY, Taylor S, Zambon M, Barclay W, Cerundolo V, Openshaw PJ, McMichael AJ, Ho LP
JCI insight 2017 Apr 6;2(7):e91868
JCI insight 2017 Apr 6;2(7):e91868
Cryopreservation-related loss of antigen-specific IFNγ producing CD4(+) T-cells can skew immunogenicity data in vaccine trials: Lessons from a malaria vaccine trial substudy.
Ford T, Wenden C, Mbekeani A, Dally L, Cox JH, Morin M, Winstone N, Hill AVS, Gilmour J, Ewer KJ
Vaccine 2017 Apr 4;35(15):1898-1906
Vaccine 2017 Apr 4;35(15):1898-1906
Twelve-year survival and immune correlates in dendritic cell-vaccinated melanoma patients.
Gross S, Erdmann M, Haendle I, Voland S, Berger T, Schultz E, Strasser E, Dankerl P, Janka R, Schliep S, Heinzerling L, Sotlar K, Coulie P, Schuler G, Schuler-Thurner B
JCI insight 2017 Apr 20;2(8)
JCI insight 2017 Apr 20;2(8)
HIV-Specific Granzyme B-Secreting but Not Gamma Interferon-Secreting T Cells Are Associated with Reduced Viral Reservoirs in Early HIV Infection.
Yue FY, Cohen JC, Ho M, Rahman AKMN, Liu J, Mujib S, Saiyed A, Hundal S, Khozin A, Bonner P, Liu D, Benko E, Kovacs C, Ostrowski M
Journal of virology 2017 Apr 15;91(8)
Journal of virology 2017 Apr 15;91(8)
HIV Controllers Exhibit Enhanced Frequencies of Major Histocompatibility Complex Class II Tetramer(+) Gag-Specific CD4(+) T Cells in Chronic Clade C HIV-1 Infection.
Laher F, Ranasinghe S, Porichis F, Mewalal N, Pretorius K, Ismail N, Buus S, Stryhn A, Carrington M, Walker BD, Ndung'u T, Ndhlovu ZM
Journal of virology 2017 Apr 1;91(7)
Journal of virology 2017 Apr 1;91(7)
Norovirus-Specific Memory T Cell Responses in Adult Human Donors.
Malm M, Tamminen K, Vesikari T, Blazevic V
Frontiers in microbiology 2016;7:1570
Frontiers in microbiology 2016;7:1570
Immune Responses to Circulating and Vaccine Viral Strains in HIV-Infected and Uninfected Children and Youth Who Received the 2013/2014 Quadrivalent Live-Attenuated Influenza Vaccine.
Weinberg A, Curtis D, Ning MF, Claypool DJ, Jalbert E, Patterson J, Frank DN, Ir D, Armon C
Frontiers in immunology 2016;7:142
Frontiers in immunology 2016;7:142
Incorporation of GM-CSF or CD40L Enhances the Immunogenicity of Hantaan Virus-Like Particles.
Cheng LF, Wang F, Zhang L, Yu L, Ye W, Liu ZY, Ying QK, Wu XA, Xu ZK, Zhang FL
Frontiers in cellular and infection microbiology 2016;6:185
Frontiers in cellular and infection microbiology 2016;6:185
mRNA-transfected dendritic cell vaccine in combination with metronomic cyclophosphamide as treatment for patients with advanced malignant melanoma.
Borch TH, Engell-Noerregaard L, Zeeberg Iversen T, Ellebaek E, Met Ö, Hansen M, Andersen MH, Thor Straten P, Svane IM
Oncoimmunology 2016;5(9):e1207842
Oncoimmunology 2016;5(9):e1207842
Phase II/III Study of Radiofrequency Ablation Combined with Cytokine-Induced Killer Cells Treating Colorectal Liver Metastases.
Li X, Dai X, Shi L, Jiang Y, Chen X, Chen L, Zhao J, Qiang W, Wu J, Ji M, Jiang J, Wu C
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;40(1-2):137-145
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;40(1-2):137-145
Single dose denileukin diftitox does not enhance vaccine-induced T cell responses or effectively deplete Tregs in advanced melanoma: immune monitoring and clinical results of a randomized phase II trial.
Luke JJ, Zha Y, Matijevich K, Gajewski TF
Journal for immunotherapy of cancer 2016;4:35
Journal for immunotherapy of cancer 2016;4:35
Peptide vaccination against multiple myeloma using peptides derived from anti-apoptotic proteins: a phase I trial.
Jørgensen NG, Ahmad SM, Abildgaard N, Straten PT, Svane IM, Andersen MH, Knudsen LM
Stem cell investigation 2016;3:95
Stem cell investigation 2016;3:95
Broad HIV-1 inhibition in vitro by vaccine-elicited CD8(+) T cells in African adults.
Mutua G, Farah B, Langat R, Indangasi J, Ogola S, Onsembe B, Kopycinski JT, Hayes P, Borthwick NJ, Ashraf A, Dally L, Barin B, Tillander A, Gilmour J, De Bont J, Crook A, Hannaman D, Cox JH, Anzala O, Fast PE, Reilly M, Chinyenze K, Jaoko W, Hanke T, Hiv-Core 004 Study Group T
Molecular therapy. Methods & clinical development 2016;3:16061
Molecular therapy. Methods & clinical development 2016;3:16061
Immunomodulatory Effects of 1,25-Dihydroxyvitamin D(3) on Dendritic Cells Promote Induction of T Cell Hyporesponsiveness to Myelin-Derived Antigens.
Lee WP, Willekens B, Cras P, Goossens H, Martínez-Cáceres E, Berneman ZN, Cools N
Journal of immunology research 2016;2016:5392623
Journal of immunology research 2016;2016:5392623
Is There Any Difference between the In Situ and Systemic IL-10 and IFN-γ Production when Clinical Forms of Cutaneous Sporotrichosis Are Compared?
Morgado FN, Schubach AO, Pimentel MI, Lyra MR, Vasconcellos ÉC, Valete-Rosalino CM, Conceição-Silva F
PloS one 2016;11(9):e0162764
PloS one 2016;11(9):e0162764
Co-Expansion of Cytokine-Induced Killer Cells and Vγ9Vδ2 T Cells for CAR T-Cell Therapy.
Du SH, Li Z, Chen C, Tan WK, Chi Z, Kwang TW, Xu XH, Wang S
PloS one 2016;11(9):e0161820
PloS one 2016;11(9):e0161820
Human Peripheral Blood Mononuclear Cell Function and Dendritic Cell Differentiation Are Affected by Bisphenol-A Exposure.
Camarca A, Gianfrani C, Ariemma F, Cimmino I, Bruzzese D, Scerbo R, Picascia S, D'Esposito V, Beguinot F, Formisano P, Valentino R
PloS one 2016;11(8):e0161122
PloS one 2016;11(8):e0161122
Use of In Vitro Assays to Assess Immunogenicity Risk of Antibody-Based Biotherapeutics.
Joubert MK, Deshpande M, Yang J, Reynolds H, Bryson C, Fogg M, Baker MP, Herskovitz J, Goletz TJ, Zhou L, Moxness M, Flynn GC, Narhi LO, Jawa V
PloS one 2016;11(8):e0159328
PloS one 2016;11(8):e0159328
Boosting with Subtype C CN54rgp140 Protein Adjuvanted with Glucopyranosyl Lipid Adjuvant after Priming with HIV-DNA and HIV-MVA Is Safe and Enhances Immune Responses: A Phase I Trial.
Joachim A, Bauer A, Joseph S, Geldmacher C, Munseri PJ, Aboud S, Missanga M, Mann P, Wahren B, Ferrari G, Polonis VR, Robb ML, Weber J, Tatoud R, Maboko L, Hoelscher M, Lyamuya EF, Biberfeld G, Sandström E, Kroidl A, Bakari M, Nilsson C, McCormack S
PloS one 2016;11(5):e0155702
PloS one 2016;11(5):e0155702
Recombinant Dengue 2 Virus NS3 Helicase Protein Enhances Antibody and T-Cell Response of Purified Inactivated Vaccine.
Simmons M, Sun P, Putnak R
PloS one 2016;11(4):e0152811
PloS one 2016;11(4):e0152811
Mucorales-Specific T Cells in Patients with Hematologic Malignancies.
Potenza L, Vallerini D, Barozzi P, Riva G, Gilioli A, Forghieri F, Candoni A, Cesaro S, Quadrelli C, Maertens J, Rossi G, Morselli M, Codeluppi M, Mussini C, Colaci E, Messerotti A, Paolini A, Maccaferri M, Fantuzzi V, Del Giovane C, Stefani A, Morandi U, Maffei R, Marasca R, Narni F, Fanin R, Comoli P, Romani L, Beauvais A, Viale PL, Latgè JP, Lewis RE, Luppi M
PloS one 2016;11(2):e0149108
PloS one 2016;11(2):e0149108
Identification of Immunogenic Cytotoxic T Lymphocyte Epitopes Containing Drug Resistance Mutations in Antiretroviral Treatment-Naïve HIV-Infected Individuals.
Blanco-Heredia J, Lecanda A, Valenzuela-Ponce H, Brander C, Ávila-Ríos S, Reyes-Terán G
PloS one 2016;11(1):e0147571
PloS one 2016;11(1):e0147571
Prediction of T Cell Epitopes from Leishmania major Potentially Excreted/Secreted Proteins Inducing Granzyme B Production.
Naouar I, Boussoffara T, Chenik M, Gritli S, Ben Ahmed M, Belhadj Hmida N, Bahi-Jaber N, Bardi R, Gorgi Y, Ben Salah A, Louzir H
PloS one 2016;11(1):e0147076
PloS one 2016;11(1):e0147076
Identification of Novel HLA-A*24:02-Restricted Epitope Derived from a Homeobox Protein Expressed in Hematological Malignancies.
Matsushita M, Otsuka Y, Tsutsumida N, Tanaka C, Uchiumi A, Ozawa K, Suzuki T, Ichikawa D, Aburatani H, Okamoto S, Kawakami Y, Hattori Y
PloS one 2016;11(1):e0146371
PloS one 2016;11(1):e0146371
Human cytomegalovirus miR-UL112-1 promotes the down-regulation of viral immediate early-gene expression during latency to prevent T-cell recognition of latently infected cells.
Lau B, Poole E, Van Damme E, Bunkens L, Sowash M, King H, Murphy E, Wills M, Van Loock M, Sinclair J
The Journal of general virology 2016 Sep;97(9):2387-2398
The Journal of general virology 2016 Sep;97(9):2387-2398
Epitope Mapping of Neutralizing Monoclonal Antibodies to Human Interferon-γ Using Human-Bovine Interferon-γ Chimeras.
Zuber B, Rudström K, Ehrnfelt C, Ahlborg N
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2016 Sep;36(9):542-51
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2016 Sep;36(9):542-51
Identification of HLA-A*11:01-restricted Mycobacterium tuberculosis CD8(+) T cell epitopes.
Liu SD, Su J, Zhang SM, Dong HP, Wang H, Luo W, Wen Q, He JC, Yang XF, Ma L
Journal of cellular and molecular medicine 2016 Sep;20(9):1718-28
Journal of cellular and molecular medicine 2016 Sep;20(9):1718-28
Structural characterization of the lipid A from the LPS of the haloalkaliphilic bacterium Halomonas pantelleriensis.
Carillo S, Pieretti G, Casillo A, Lindner B, Romano I, Nicolaus B, Parrilli M, Giuliano M, Cammarota M, Lanzetta R, Corsaro MM
Extremophiles : life under extreme conditions 2016 Sep;20(5):687-94
Extremophiles : life under extreme conditions 2016 Sep;20(5):687-94
Combination treatment with decitabine and ionizing radiation enhances tumor cells susceptibility of T cells.
Son CH, Lee HR, Koh EK, Shin DY, Bae JH, Yang K, Park YS
Scientific reports 2016 Sep 27;6:32470
Scientific reports 2016 Sep 27;6:32470
Adjuvanted multi-epitope vaccines protect HLA-A*11:01 transgenic mice against Toxoplasma gondii.
El Bissati K, Chentoufi AA, Krishack PA, Zhou Y, Woods S, Dubey JP, Vang L, Lykins J, Broderick KE, Mui E, Suzuki Y, Sa Q, Bi S, Cardona N, Verma SK, Fraczek L, Reardon CA, Sidney J, Alexander J, Sette A, Vedvick T, Fox C, Guderian JA, Reed S, Roberts CW, McLeod R
JCI insight 2016 Sep 22;1(15):e85955
JCI insight 2016 Sep 22;1(15):e85955
Epstein-Barr viral miRNAs inhibit antiviral CD4+ T cell responses targeting IL-12 and peptide processing.
Tagawa T, Albanese M, Bouvet M, Moosmann A, Mautner J, Heissmeyer V, Zielinski C, Lutter D, Hoser J, Hastreiter M, Hayes M, Sugden B, Hammerschmidt W
The Journal of experimental medicine 2016 Sep 19;213(10):2065-80
The Journal of experimental medicine 2016 Sep 19;213(10):2065-80
Abnormal thymic stromal lymphopoietin expression in the duodenal mucosa of patients with coeliac disease.
Biancheri P, Di Sabatino A, Rescigno M, Giuffrida P, Fornasa G, Tsilingiri K, Pender SL, Papadia C, Wood E, Pasini A, Ubezio C, Vanoli A, Forbes A, MacDonald TT, Corazza GR
Gut 2016 Oct;65(10):1670-80
Gut 2016 Oct;65(10):1670-80
Vaccination Against Human Papilloma Viruses Leads to a Favorable Cytokine Profile of Specific T Cells.
Luckau S, Wehrs TP, Brandau S, Horn PA, Lindemann M
Journal of immunotherapy (Hagerstown, Md. : 1997) 2016 Oct;39(8):316-20
Journal of immunotherapy (Hagerstown, Md. : 1997) 2016 Oct;39(8):316-20
Circulating functional T cells specific to human herpes virus 6 (HHV6) antigens in individuals with chromosomally integrated HHV6.
Barozzi P, Riva G, Vallerini D, Quadrelli C, Lagreca I, Eccheli R, Forghieri F, Coluccio V, Maccaferri M, Paolini A, Colaci E, Morselli M, Marasca R, Narni F, Comoli P, Campioli D, Trenti T, Potenza L, Luppi M
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 2016 Oct;22(10):893-895
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 2016 Oct;22(10):893-895
Comparison of Three Isolation Techniques for Human Peripheral Blood Mononuclear Cells: Cell Recovery and Viability, Population Composition, and Cell Functionality.
Grievink HW, Luisman T, Kluft C, Moerland M, Malone KE
Biopreservation and biobanking 2016 Oct;14(5):410-415
Biopreservation and biobanking 2016 Oct;14(5):410-415
Defective T Memory Cell Differentiation after Varicella Zoster Vaccination in Older Individuals.
Qi Q, Cavanagh MM, Le Saux S, Wagar LE, Mackey S, Hu J, Maecker H, Swan GE, Davis MM, Dekker CL, Tian L, Weyand CM, Goronzy JJ
PLoS pathogens 2016 Oct;12(10):e1005892
PLoS pathogens 2016 Oct;12(10):e1005892
Protective Efficacy of Plasmodium vivax Radiation-Attenuated Sporozoites in Colombian Volunteers: A Randomized Controlled Trial.
Arévalo-Herrera M, Vásquez-Jiménez JM, Lopez-Perez M, Vallejo AF, Amado-Garavito AB, Céspedes N, Castellanos A, Molina K, Trejos J, Oñate J, Epstein JE, Richie TL, Herrera S
PLoS neglected tropical diseases 2016 Oct;10(10):e0005070
PLoS neglected tropical diseases 2016 Oct;10(10):e0005070
Epstein-Barr virus microRNAs reduce immune surveillance by virus-specific CD8+ T cells.
Albanese M, Tagawa T, Bouvet M, Maliqi L, Lutter D, Hoser J, Hastreiter M, Hayes M, Sugden B, Martin L, Moosmann A, Hammerschmidt W
Proceedings of the National Academy of Sciences of the United States of America 2016 Oct 18;113(42):E6467-E6475
Proceedings of the National Academy of Sciences of the United States of America 2016 Oct 18;113(42):E6467-E6475
Psoriatic T cells recognize neolipid antigens generated by mast cell phospholipase delivered by exosomes and presented by CD1a.
Cheung KL, Jarrett R, Subramaniam S, Salimi M, Gutowska-Owsiak D, Chen YL, Hardman C, Xue L, Cerundolo V, Ogg G
The Journal of experimental medicine 2016 Oct 17;213(11):2399-2412
The Journal of experimental medicine 2016 Oct 17;213(11):2399-2412
CD8(+) T cell response to human papillomavirus 16 E7 is able to predict survival outcome in oropharyngeal cancer.
Masterson L, Lechner M, Loewenbein S, Mohammed H, Davies-Husband C, Fenton T, Sudhoff H, Jani P, Goon P, Sterling J
European journal of cancer (Oxford, England : 1990) 2016 Nov;67:141-151
European journal of cancer (Oxford, England : 1990) 2016 Nov;67:141-151
Protective Role of Cross-Reactive CD8 T Cells Against Dengue Virus Infection.
Elong Ngono A, Chen HW, Tang WW, Joo Y, King K, Weiskopf D, Sidney J, Sette A, Shresta S
EBioMedicine 2016 Nov;13:284-293
EBioMedicine 2016 Nov;13:284-293
The CD8⁺ T Cell-Mediated Immunity Induced by HPV-E6 Uploaded in Engineered Exosomes Is Improved by ISCOMATRIX(TM) Adjuvant.
Manfredi F, di Bonito P, Ridolfi B, Anticoli S, Arenaccio C, Chiozzini C, Baz Morelli A, Federico M
Vaccines 2016 Nov 9;4(4)
Vaccines 2016 Nov 9;4(4)
A phase 1, randomized, controlled dose-escalation study of EP-1300 polyepitope DNA vaccine against Plasmodium falciparum malaria administered via electroporation.
Spearman P, Mulligan M, Anderson EJ, Shane AL, Stephens K, Gibson T, Hartwell B, Hannaman D, Watson NL, Singh K
Vaccine 2016 Nov 4;34(46):5571-5578
Vaccine 2016 Nov 4;34(46):5571-5578
Graft versus self (GvS) against T-cell autoantigens is a mechanism of graft-host interaction.
Mirza N, Zierhut M, Korn A, Bornemann A, Vogel W, Schmid-Horch B, Bethge WA, Stevanović S, Salih HR, Kanz L, Rammensee HG, Haen SP
Proceedings of the National Academy of Sciences of the United States of America 2016 Nov 29;113(48):13827-13832
Proceedings of the National Academy of Sciences of the United States of America 2016 Nov 29;113(48):13827-13832
Direct identification of clinically relevant neoepitopes presented on native human melanoma tissue by mass spectrometry.
Bassani-Sternberg M, Bräunlein E, Klar R, Engleitner T, Sinitcyn P, Audehm S, Straub M, Weber J, Slotta-Huspenina J, Specht K, Martignoni ME, Werner A, Hein R, H Busch D, Peschel C, Rad R, Cox J, Mann M, Krackhardt AM
Nature communications 2016 Nov 21;7:13404
Nature communications 2016 Nov 21;7:13404
Matrix metalloproteinase-10 is a target of T and B cell responses that correlate with synovial pathology in patients with antibiotic-refractory Lyme arthritis.
Crowley JT, Strle K, Drouin EE, Pianta A, Arvikar SL, Wang Q, Costello CE, Steere AC
Journal of autoimmunity 2016 May;69:24-37
Journal of autoimmunity 2016 May;69:24-37
Diagnosis of latent tuberculosis by ELISPOT assay and tuberculin skin test.
Du F, Zhang Z, Gao T, Liu Z, Jia H, Xing A, Du B, Sun Q, Cao T, Zhang Z
Medecine et maladies infectieuses 2016 May;46(3):150-3
Medecine et maladies infectieuses 2016 May;46(3):150-3
Immunostimulatory Activity of the Cytokine-Based Biologic, IRX-2, on Human Papillomavirus-Exposed Langerhans Cells.
Da Silva DM, Woodham AW, Naylor PH, Egan JE, Berinstein NL, Kast WM
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2016 May;36(5):291-301
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2016 May;36(5):291-301
Evaluating the Role of Cellular Immune Responses in the Emergence of HCV NS3 Resistance Mutations During Protease Inhibitor Therapy.
Abdel-Hameed EA, Rouster SD, Ji H, Ulm A, Hetta HF, Anwar N, Sherman KE, Shata MT
Viral immunology 2016 May;29(4):252-8
Viral immunology 2016 May;29(4):252-8
Functional cloning of a gp100-reactive T-cell receptor from vitiligo patient skin.
Klarquist J, Eby JM, Henning SW, Li M, Wainwright DA, Westerhof W, Luiten RM, Nishimura MI, Le Poole IC
Pigment cell & melanoma research 2016 May;29(3):379-84
Pigment cell & melanoma research 2016 May;29(3):379-84
Phase I clinical trial of a five-peptide cancer vaccine combined with cyclophosphamide in advanced solid tumors.
Murahashi M, Hijikata Y, Yamada K, Tanaka Y, Kishimoto J, Inoue H, Marumoto T, Takahashi A, Okazaki T, Takeda K, Hirakawa M, Fujii H, Okano S, Morita M, Baba E, Mizumoto K, Maehara Y, Tanaka M, Akashi K, Nakanishi Y, Yoshida K, Tsunoda T, Tamura K, Nakamura Y, Tani K
Clinical immunology (Orlando, Fla.) 2016 May;166-167:48-58
Clinical immunology (Orlando, Fla.) 2016 May;166-167:48-58
Discovery of the First α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Antagonist Dependent upon Transmembrane AMPA Receptor Regulatory Protein (TARP) γ-8.
Gardinier KM, Gernert DL, Porter WJ, Reel JK, Ornstein PL, Spinazze P, Stevens FC, Hahn P, Hollinshead SP, Mayhugh D, Schkeryantz J, Khilevich A, De Frutos O, Gleason SD, Kato AS, Luffer-Atlas D, Desai PV, Swanson S, Burris KD, Ding C, Heinz BA, Need AB, Barth VN, Stephenson GA, Diseroad BA, Woods TA, Yu H, Bredt D, Witkin JM
Journal of medicinal chemistry 2016 May 26;59(10):4753-68
Journal of medicinal chemistry 2016 May 26;59(10):4753-68
Novel HLA-A2-restricted human metapneumovirus epitopes reduce viral titers in mice and are recognized by human T cells.
Hastings AK, Gilchuk P, Joyce S, Williams JV
Vaccine 2016 May 23;34(24):2663-70
Vaccine 2016 May 23;34(24):2663-70
The Antitumor Efficacy of IL2/IL21-Cultured Polyfunctional Neu-Specific T Cells Is TNFα/IL17 Dependent.
Phan-Lai V, Dang Y, Gad E, Childs J, Disis ML
Clinical cancer research : an official journal of the American Association for Cancer Research 2016 May 1;22(9):2207-16
Clinical cancer research : an official journal of the American Association for Cancer Research 2016 May 1;22(9):2207-16
Mechanisms of immune escape in central nervous system infection with neurotropic JC virus variant.
Jelcic I, Jelcic I, Kempf C, Largey F, Planas R, Schippling S, Budka H, Sospedra M, Martin R
Annals of neurology 2016 Mar;79(3):404-18
Annals of neurology 2016 Mar;79(3):404-18
T-cell libraries allow simple parallel generation of multiple peptide-specific human T-cell clones.
Theaker SM, Rius C, Greenshields-Watson A, Lloyd A, Trimby A, Fuller A, Miles JJ, Cole DK, Peakman M, Sewell AK, Dolton G
Journal of immunological methods 2016 Mar;430:43-50
Journal of immunological methods 2016 Mar;430:43-50
Markers of Protection in Children and Adolescents Six to Fourteen Years After Primary Hepatitis B Vaccination in Real Life: A Pilot Study.
Brunskole Hummel I, Huber B, Wenzel JJ, Jilg W
The Pediatric infectious disease journal 2016 Mar;35(3):286-91
The Pediatric infectious disease journal 2016 Mar;35(3):286-91
CD4(+) and CD8(+) TCRβ repertoires possess different potentials to generate extraordinarily high-avidity T cells.
Nakatsugawa M, Rahman MA, Yamashita Y, Ochi T, Wnuk P, Tanaka S, Chamoto K, Kagoya Y, Saso K, Guo T, Anczurowski M, Butler MO, Hirano N
Scientific reports 2016 Mar 31;6:23821
Scientific reports 2016 Mar 31;6:23821
Enhanced Cytotoxic CD8 T Cell Priming Using Dendritic Cell-Expressing Human Papillomavirus-16 E6/E7-p16INK4 Fusion Protein with Sequenced Anti-Programmed Death-1.
Garcia-Bates TM, Kim E, Concha-Benavente F, Trivedi S, Mailliard RB, Gambotto A, Ferris RL
Journal of immunology (Baltimore, Md. : 1950) 2016 Mar 15;196(6):2870-8
Journal of immunology (Baltimore, Md. : 1950) 2016 Mar 15;196(6):2870-8
Transgenic antigen-specific, HLA-A*02:01-allo-restricted cytotoxic T cells recognize tumor-associated target antigen STEAP1 with high specificity.
Schirmer D, Grünewald TG, Klar R, Schmidt O, Wohlleber D, Rubío RA, Uckert W, Thiel U, Bohne F, Busch DH, Krackhardt AM, Burdach S, Richter GH
Oncoimmunology 2016 Jun;5(6):e1175795
Oncoimmunology 2016 Jun;5(6):e1175795
Human CD8(+) T Cells Target Multiple Epitopes in Respiratory Syncytial Virus Polymerase.
Burbulla D, Günther PS, Peper JK, Jahn G, Dennehy KM
Viral immunology 2016 Jun;29(5):307-14
Viral immunology 2016 Jun;29(5):307-14
Reconstitution of cytomegalovirus-specific T-cell response in allogeneic hematopoietic stem cell recipients: the contribution of six frequently recognized, virus-encoded ORFs.
Nemeckova S, Krystofova J, Babiarova K, Hainz P, Musil J, Sroller V, Maly M, Stastna-Markova M
Transplant infectious disease : an official journal of the Transplantation Society 2016 Jun;18(3):381-9
Transplant infectious disease : an official journal of the Transplantation Society 2016 Jun;18(3):381-9
Effect of mTORC1/mTORC2 inhibition on T cell function: potential role in graft-versus-host disease control.
Herrero-Sánchez MC, Rodríguez-Serrano C, Almeida J, San-Segundo L, Inogés S, Santos-Briz Á, García-Briñón J, SanMiguel JF, Del Cañizo C, Blanco B
British journal of haematology 2016 Jun;173(5):754-68
British journal of haematology 2016 Jun;173(5):754-68
Aberrant Glycosylation of Anchor-Optimized MUC1 Peptides Can Enhance Antigen Binding Affinity and Reverse Tolerance to Cytotoxic T Lymphocytes.
Pathangey LB, Lakshminarayanan V, Suman VJ, Pockaj BA, Mukherjee P, Gendler SJ
Biomolecules 2016 Jun 29;6(3)
Biomolecules 2016 Jun 29;6(3)
Human T cell responses to Japanese encephalitis virus in health and disease.
Turtle L, Bali T, Buxton G, Chib S, Chan S, Soni M, Hussain M, Isenman H, Fadnis P, Venkataswamy MM, Satishkumar V, Lewthwaite P, Kurioka A, Krishna S, Shankar MV, Ahmed R, Begum A, Ravi V, Desai A, Yoksan S, Fernandez S, Willberg CB, Kloverpris HN, Conlon C, Klenerman P, Satchidanandam V, Solomon T
The Journal of experimental medicine 2016 Jun 27;213(7):1331-52
The Journal of experimental medicine 2016 Jun 27;213(7):1331-52
Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy.
Kranz LM, Diken M, Haas H, Kreiter S, Loquai C, Reuter KC, Meng M, Fritz D, Vascotto F, Hefesha H, Grunwitz C, Vormehr M, Hüsemann Y, Selmi A, Kuhn AN, Buck J, Derhovanessian E, Rae R, Attig S, Diekmann J, Jabulowsky RA, Heesch S, Hassel J, Langguth P, Grabbe S, Huber C, Türeci Ö, Sahin U
Nature 2016 Jun 16;534(7607):396-401
Nature 2016 Jun 16;534(7607):396-401
Serotype-Specific Cell-Mediated Immunity Associated With Clearance of Homotypic Group B Streptococcus Rectovaginal Colonization in Pregnant Women.
Kwatra G, Adrian PV, Shiri T, Izu A, Cutland CL, Buchmann EJ, Madhi SA
The Journal of infectious diseases 2016 Jun 15;213(12):1923-6
The Journal of infectious diseases 2016 Jun 15;213(12):1923-6
Validation of an IFNγ/IL2 FluoroSpot assay for clinical trial monitoring.
Körber N, Behrends U, Hapfelmeier A, Protzer U, Bauer T
Journal of translational medicine 2016 Jun 14;14(1):175
Journal of translational medicine 2016 Jun 14;14(1):175
Multiple T-cell responses are associated with better control of acute HIV-1 infection: An observational study.
Sun J, Zhao Y, Peng Y, Han Z, Liu G, Qin L, Liu S, Sun H, Wu H, Dong T, Zhang Y
Medicine 2016 Jul;95(30):e4429
Medicine 2016 Jul;95(30):e4429
PD-L1-specific T cells.
Ahmad SM, Borch TH, Hansen M, Andersen MH
Cancer immunology, immunotherapy : CII 2016 Jul;65(7):797-804
Cancer immunology, immunotherapy : CII 2016 Jul;65(7):797-804
Granulocyte colony-stimulating factor impairs CD8(+) T cell functionality by interfering with central activation elements.
Bunse CE, Tischer S, Lahrberg J, Oelke M, Figueiredo C, Blasczyk R, Eiz-Vesper B
Clinical and experimental immunology 2016 Jul;185(1):107-18
Clinical and experimental immunology 2016 Jul;185(1):107-18
A Quantitative Analysis of Complexity of Human Pathogen-Specific CD4 T Cell Responses in Healthy M. tuberculosis Infected South Africans.
Lindestam Arlehamn CS, McKinney DM, Carpenter C, Paul S, Rozot V, Makgotlho E, Gregg Y, van Rooyen M, Ernst JD, Hatherill M, Hanekom WA, Peters B, Scriba TJ, Sette A
PLoS pathogens 2016 Jul;12(7):e1005760
PLoS pathogens 2016 Jul;12(7):e1005760
In vitro rapid diagnostic tests for severe drug hypersensitivity reactions in children.
Haw WY, Polak ME, McGuire C, Erlewyn-Lajeunesse M, Ardern-Jones MR
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2016 Jul;117(1):61-6
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2016 Jul;117(1):61-6
A Longitudinal Hepatitis B Vaccine Cohort Demonstrates Long-lasting Hepatitis B Virus (HBV) Cellular Immunity Despite Loss of Antibody Against HBV Surface Antigen.
Simons BC, Spradling PR, Bruden DJ, Zanis C, Case S, Choromanski TL, Apodaca M, Brogdon HD, Dwyer G, Snowball M, Negus S, Bruce MG, Morishima C, Knall C, McMahon BJ
The Journal of infectious diseases 2016 Jul 15;214(2):273-80
The Journal of infectious diseases 2016 Jul 15;214(2):273-80
Transcriptional Profiling of Th2 Cells Identifies Pathogenic Features Associated with Asthma.
Seumois G, Zapardiel-Gonzalo J, White B, Singh D, Schulten V, Dillon M, Hinz D, Broide DH, Sette A, Peters B, Vijayanand P
Journal of immunology (Baltimore, Md. : 1950) 2016 Jul 15;197(2):655-64
Journal of immunology (Baltimore, Md. : 1950) 2016 Jul 15;197(2):655-64
MiR-381-3p Regulates the Antigen-Presenting Capability of Dendritic Cells and Represses Antituberculosis Cellular Immune Responses by Targeting CD1c.
Wen Q, Zhou C, Xiong W, Su J, He J, Zhang S, Du X, Liu S, Wang J, Ma L
Journal of immunology (Baltimore, Md. : 1950) 2016 Jul 15;197(2):580-9
Journal of immunology (Baltimore, Md. : 1950) 2016 Jul 15;197(2):580-9
Adjuvant Immunotherapy to Improve Outcome in High-Risk Pediatric Sarcomas.
Merchant MS, Bernstein D, Amoako M, Baird K, Fleisher TA, Morre M, Steinberg SM, Sabatino M, Stroncek DF, Venkatasan AM, Wood BJ, Wright M, Zhang H, Mackall CL
Clinical cancer research : an official journal of the American Association for Cancer Research 2016 Jul 1;22(13):3182-91
Clinical cancer research : an official journal of the American Association for Cancer Research 2016 Jul 1;22(13):3182-91
Elevated and cross-responsive CD1a-reactive T cells in bee and wasp venom allergic individuals.
Subramaniam S, Aslam A, Misbah SA, Salio M, Cerundolo V, Moody DB, Ogg G
European journal of immunology 2016 Jan;46(1):242-52
European journal of immunology 2016 Jan;46(1):242-52
Characteristics of immune memory 10-15 years after primary hepatitis B vaccination.
Brunskole Hummel I, Zitzmann A, Erl M, Wenzel JJ, Jilg W
Vaccine 2016 Jan 27;34(5):636-642
Vaccine 2016 Jan 27;34(5):636-642
Human autoreactive T cells recognize CD1b and phospholipids.
Van Rhijn I, van Berlo T, Hilmenyuk T, Cheng TY, Wolf BJ, Tatituri RV, Uldrich AP, Napolitani G, Cerundolo V, Altman JD, Willemsen P, Huang S, Rossjohn J, Besra GS, Brenner MB, Godfrey DI, Moody DB
Proceedings of the National Academy of Sciences of the United States of America 2016 Jan 12;113(2):380-5
Proceedings of the National Academy of Sciences of the United States of America 2016 Jan 12;113(2):380-5
The Tumor Antigen NY-ESO-1 Mediates Direct Recognition of Melanoma Cells by CD4+ T Cells after Intercellular Antigen Transfer.
Fonteneau JF, Brilot F, Münz C, Gannagé M
Journal of immunology (Baltimore, Md. : 1950) 2016 Jan 1;196(1):64-71
Journal of immunology (Baltimore, Md. : 1950) 2016 Jan 1;196(1):64-71
Monocyte Stabilin-1 Suppresses the Activation of Th1 Lymphocytes.
Palani S, Elima K, Ekholm E, Jalkanen S, Salmi M
Journal of immunology (Baltimore, Md. : 1950) 2016 Jan 1;196(1):115-23
Journal of immunology (Baltimore, Md. : 1950) 2016 Jan 1;196(1):115-23
Population tailored modification of tuberculosis specific interferon-gamma release assay.
Horvati K, Bősze S, Gideon HP, Bacsa B, Szabó TG, Goliath R, Rangaka MX, Hudecz F, Wilkinson RJ, Wilkinson KA
The Journal of infection 2016 Feb;72(2):179-88
The Journal of infection 2016 Feb;72(2):179-88
Immunoregulatory effects on T lymphocytes by human mesenchymal stromal cells isolated from bone marrow, amniotic fluid, and placenta.
Mareschi K, Castiglia S, Sanavio F, Rustichelli D, Muraro M, Defedele D, Bergallo M, Fagioli F
Experimental hematology 2016 Feb;44(2):138-150.e1
Experimental hematology 2016 Feb;44(2):138-150.e1
Human Wharton's jelly-derived mesenchymal stromal cells engineered to secrete Epstein-Barr virus interleukin-10 show enhanced immunosuppressive properties.
Quaranta P, Focosi D, Di Iesu M, Cursi C, Zucca A, Curcio M, Lapi S, Boldrini L, Stampacchia G, Paolicchi A, Scatena F, Freer G, Pistello M
Cytotherapy 2016 Feb;18(2):205-18
Cytotherapy 2016 Feb;18(2):205-18
Chronic and recurrent benign lymphadenopathy without constitutional symptoms associated with human herpesvirus-6B reactivation.
Forghieri F, Luppi M, Barozzi P, Riva G, Morselli M, Bigliardi S, Quadrelli C, Vallerini D, Maccaferri M, Coluccio V, Paolini A, Colaci E, Bonacorsi G, Maiorana A, Tagliazucchi S, Rumpianesi F, Mattioli F, Presutti L, Gelmini R, Cermelli C, Rossi G, Comoli P, Marasca R, Narni F, Potenza L
British journal of haematology 2016 Feb;172(4):561-72
British journal of haematology 2016 Feb;172(4):561-72
Reduced naïve CD8(+) T-cell priming efficacy in elderly adults.
Briceño O, Lissina A, Wanke K, Afonso G, von Braun A, Ragon K, Miquel T, Gostick E, Papagno L, Stiasny K, Price DA, Mallone R, Sauce D, Karrer U, Appay V
Aging cell 2016 Feb;15(1):14-21
Aging cell 2016 Feb;15(1):14-21
Expansion of Tumor-reactive T Cells From Patients With Pancreatic Cancer.
Meng Q, Liu Z, Rangelova E, Poiret T, Ambati A, Rane L, Xie S, Verbeke C, Dodoo E, Del Chiaro M, Löhr M, Segersvärd R, Maeurer MJ
Journal of immunotherapy (Hagerstown, Md. : 1997) 2016 Feb-Mar;39(2):81-9
Journal of immunotherapy (Hagerstown, Md. : 1997) 2016 Feb-Mar;39(2):81-9
CD46 Activation Regulates miR-150-Mediated Control of GLUT1 Expression and Cytokine Secretion in Human CD4+ T Cells.
King BC, Esguerra JL, Golec E, Eliasson L, Kemper C, Blom AM
Journal of immunology (Baltimore, Md. : 1950) 2016 Feb 15;196(4):1636-45
Journal of immunology (Baltimore, Md. : 1950) 2016 Feb 15;196(4):1636-45
Filaggrin inhibits generation of CD1a neolipid antigens by house dust mite-derived phospholipase.
Jarrett R, Salio M, Lloyd-Lavery A, Subramaniam S, Bourgeois E, Archer C, Cheung KL, Hardman C, Chandler D, Salimi M, Gutowska-Owsiak D, de la Serna JB, Fallon PG, Jolin H, Mckenzie A, Dziembowski A, Podobas EI, Bal W, Johnson D, Moody DB, Cerundolo V, Ogg G
Science translational medicine 2016 Feb 10;8(325):325ra18
Science translational medicine 2016 Feb 10;8(325):325ra18
Effect of Depot Medoxyprogesterone Acetate on Immune Functions and Inflammatory Markers of HIV-Infected Women.
Weinberg A, Park JG, Bosch R, Cho A, Livingston E, Aweeka F, Cramer Y, Watts DH, Luque AE, Cohn SE
Journal of acquired immune deficiency syndromes (1999) 2016 Feb 1;71(2):137-45
Journal of acquired immune deficiency syndromes (1999) 2016 Feb 1;71(2):137-45
Measurement of ex vivo ELISpot interferon-gamma recall responses to Plasmodium falciparum AMA1 and CSP in Ghanaian adults with natural exposure to malaria.
Ganeshan H, Kusi KA, Anum D, Hollingdale MR, Peters B, Kim Y, Tetteh JK, Ofori MF, Gyan BA, Koram KA, Huang J, Belmonte M, Banania JG, Dodoo D, Villasante E, Sedegah M
Malaria journal 2016 Feb 1;15:55
Malaria journal 2016 Feb 1;15:55
Phase I/II trial of combination of temozolomide chemotherapy and immunotherapy with fusions of dendritic and glioma cells in patients with glioblastoma.
Akasaki Y, Kikuchi T, Homma S, Koido S, Ohkusa T, Tasaki T, Hayashi K, Komita H, Watanabe N, Suzuki Y, Yamamoto Y, Mori R, Arai T, Tanaka T, Joki T, Yanagisawa T, Murayama Y
Cancer immunology, immunotherapy : CII 2016 Dec;65(12):1499-1509
Cancer immunology, immunotherapy : CII 2016 Dec;65(12):1499-1509
Human parainfluenza virus-3 can be targeted by rapidly ex vivo expanded T lymphocytes.
McLaughlin LP, Lang H, Williams E, Wright KE, Powell A, Cruz CR, Colberg-Poley AM, Barese C, Hanley PJ, Bollard CM, Keller MD
Cytotherapy 2016 Dec;18(12):1515-1524
Cytotherapy 2016 Dec;18(12):1515-1524
Detection of Primary T Cell Responses to Drugs and Chemicals in HLA-Typed Volunteers: Implications for the Prediction of Drug Immunogenicity.
Faulkner L, Gibson A, Sullivan A, Tailor A, Usui T, Alfirevic A, Pirmohamed M, Naisbitt DJ, Kevin Park B
Toxicological sciences : an official journal of the Society of Toxicology 2016 Dec;154(2):416-429
Toxicological sciences : an official journal of the Society of Toxicology 2016 Dec;154(2):416-429
Toward Optimal Cryopreservation and Storage for Achievement of High Cell Recovery and Maintenance of Cell Viability and T Cell Functionality.
Angel S, von Briesen H, Oh YJ, Baller MK, Zimmermann H, Germann A
Biopreservation and biobanking 2016 Dec;14(6):539-547
Biopreservation and biobanking 2016 Dec;14(6):539-547
Cytomegalovirus-Specific IL-10-Producing CD4+ T Cells Are Governed by Type-I IFN-Induced IL-27 and Promote Virus Persistence.
Clement M, Marsden M, Stacey MA, Abdul-Karim J, Gimeno Brias S, Costa Bento D, Scurr MJ, Ghazal P, Weaver CT, Carlesso G, Clare S, Jones SA, Godkin A, Jones GW, Humphreys IR
PLoS pathogens 2016 Dec;12(12):e1006050
PLoS pathogens 2016 Dec;12(12):e1006050
An escalating dose study to assess the safety, tolerability and immunogenicity of a Herpes Simplex Virus DNA vaccine, COR-1.
Dutton JL, Woo WP, Chandra J, Xu Y, Li B, Finlayson N, Griffin P, Frazer IH
Human vaccines & immunotherapeutics 2016 Dec;12(12):3079-3088
Human vaccines & immunotherapeutics 2016 Dec;12(12):3079-3088
A functional polymorphism in the NKG2D gene modulates NK-cell cytotoxicity and is associated with susceptibility to Human Papilloma Virus-related cancers.
Espinoza JL, Nguyen VH, Ichimura H, Pham TT, Nguyen CH, Pham TV, Elbadry MI, Yoshioka K, Tanaka J, Trung LQ, Takami A, Nakao S
Scientific reports 2016 Dec 20;6:39231
Scientific reports 2016 Dec 20;6:39231
Processing and MHC class II presentation of exogenous soluble antigen involving a proteasome-dependent cytosolic pathway in CD40-activated B cells.
Becker HJ, Kondo E, Shimabukuro-Vornhagen A, Theurich S, von Bergwelt-Baildon MS
European journal of haematology 2016 Aug;97(2):166-74
European journal of haematology 2016 Aug;97(2):166-74
Establishment and characterization of a highly immunogenic human renal carcinoma cell line.
Prattichizzo C, Gigante M, Pontrelli P, Stella A, Rocchetti MT, Gigante M, Maiorano E, Herr W, Battaglia M, Gesualdo L, Ranieri E
International journal of oncology 2016 Aug;49(2):457-70
International journal of oncology 2016 Aug;49(2):457-70
Expanded lung T-bet+RORγT+ CD4+ T-cells in sarcoidosis patients with a favourable disease phenotype.
Kaiser Y, Lepzien R, Kullberg S, Eklund A, Smed-Sörensen A, Grunewald J
The European respiratory journal 2016 Aug;48(2):484-94
The European respiratory journal 2016 Aug;48(2):484-94
A statistical approach to determining responses to individual peptides from pooled-peptide ELISpot data.
Ström P, Støer N, Borthwick N, Dong T, Hanke T, Reilly M
Journal of immunological methods 2016 Aug;435:43-9
Journal of immunological methods 2016 Aug;435:43-9
Identification of proteins derived from Listeria monocytogenes inducing human dendritic cell maturation.
Mirzaei R, Saei A, Torkashvand F, Azarian B, Jalili A, Noorbakhsh F, Vaziri B, Hadjati J
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Aug;37(8):10893-907
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Aug;37(8):10893-907
Safety, immune and clinical responses in metastatic melanoma patients vaccinated with a long peptide derived from indoleamine 2,3-dioxygenase in combination with ipilimumab.
Bjoern J, Iversen TZ, Nitschke NJ, Andersen MH, Svane IM
Cytotherapy 2016 Aug;18(8):1043-1055
Cytotherapy 2016 Aug;18(8):1043-1055
Human TRAV1-2-negative MR1-restricted T cells detect S. pyogenes and alternatives to MAIT riboflavin-based antigens.
Meermeier EW, Laugel BF, Sewell AK, Corbett AJ, Rossjohn J, McCluskey J, Harriff MJ, Franks T, Gold MC, Lewinsohn DM
Nature communications 2016 Aug 16;7:12506
Nature communications 2016 Aug 16;7:12506
Development of an IFNγ ELISPOT for the analysis of the human T cell response against mumps virus.
Han WG, Emmelot ME, Jaadar H, Ten Hulscher HI, van Els CA, Kaaijk P
Journal of immunological methods 2016 Apr;431:52-9
Journal of immunological methods 2016 Apr;431:52-9
Analysis of HIV-1c-Specific CTL Responses with HIV-1 Reservoir Size and Forms.
Kang W, Zhu W, Li Y, Jiao Y, Zhuang Y, Xie Y, Zhao K, Dang B, Liu Q, Zhang Y, Sun Y
Viral immunology 2016 Apr;29(3):184-91
Viral immunology 2016 Apr;29(3):184-91
Cellular Interferon Gamma and Granzyme B Responses to Cytomegalovirus-pp65 and Influenza N1 Are Positively Associated in Elderly.
Theeten H, Mathei C, Peeters K, Ogunjimi B, Goossens H, Ieven M, Van Damme P, Cools N
Viral immunology 2016 Apr;29(3):169-75
Viral immunology 2016 Apr;29(3):169-75
Dendritic-tumor cell hybrids induce tumor-specific immune responses more effectively than the simple mixture of dendritic and tumor cells.
Pinho MP, Sundarasetty BS, Bergami-Santos PC, Steponavicius-Cruz K, Ferreira AK, Stripecke R, Barbuto JA
Cytotherapy 2016 Apr;18(4):570-80
Cytotherapy 2016 Apr;18(4):570-80
Higher numbers of memory B-cells and Th2-cytokine skewing in high responders to hepatitis B vaccination.
Doedée AM, Kannegieter N, Öztürk K, van Loveren H, Janssen R, Buisman AM
Vaccine 2016 Apr 27;34(19):2281-9
Vaccine 2016 Apr 27;34(19):2281-9
Dasatinib inhibits HIV-1 replication through the interference of SAMHD1 phosphorylation in CD4+ T cells.
Bermejo M, López-Huertas MR, García-Pérez J, Climent N, Descours B, Ambrosioni J, Mateos E, Rodríguez-Mora S, Rus-Bercial L, Benkirane M, Miró JM, Plana M, Alcamí J, Coiras M
Biochemical pharmacology 2016 Apr 15;106:30-45
Biochemical pharmacology 2016 Apr 15;106:30-45
T-cell activation is an immune correlate of risk in BCG vaccinated infants.
Fletcher HA, Snowden MA, Landry B, Rida W, Satti I, Harris SA, Matsumiya M, Tanner R, O'Shea MK, Dheenadhayalan V, Bogardus L, Stockdale L, Marsay L, Chomka A, Harrington-Kandt R, Manjaly-Thomas ZR, Naranbhai V, Stylianou E, Darboe F, Penn-Nicholson A, Nemes E, Hatherill M, Hussey G, Mahomed H, Tameris M, McClain JB, Evans TG, Hanekom WA, Scriba TJ, McShane H
Nature communications 2016 Apr 12;7:11290
Nature communications 2016 Apr 12;7:11290
A Diverse Repertoire of CD4 T Cells Targets the Immediate-Early 1 Protein of Human Cytomegalovirus.
Ameres S, Liang X, Wiesner M, Mautner J, Moosmann A
Frontiers in immunology 2015;6:598
Frontiers in immunology 2015;6:598
Boosted Influenza-Specific T Cell Responses after H5N1 Pandemic Live Attenuated Influenza Virus Vaccination.
Peng Y, Wang B, Talaat K, Karron R, Powell TJ, Zeng H, Dong D, Luke CJ, McMichael A, Subbarao K, Dong T
Frontiers in immunology 2015;6:287
Frontiers in immunology 2015;6:287
The immunological footprint of CMV in HIV-1 patients stable on long-term ART.
Affandi JS, Montgomery J, Brunt SJ, Nolan D, Price P
Immunity & ageing : I & A 2015;12:14
Immunity & ageing : I & A 2015;12:14
Pre-Vaccination Frequencies of Th17 Cells Correlate with Vaccine-Induced T-Cell Responses to Survivin-Derived Peptide Epitopes.
Køllgaard T, Ugurel-Becker S, Idorn M, Andersen MH, Becker JC, Straten PT
PloS one 2015;10(7):e0131934
PloS one 2015;10(7):e0131934
Study of the BCG Vaccine-Induced Cellular Immune Response in Schoolchildren in Antananarivo, Madagascar.
Ranaivomanana P, Raharimanga V, Dubois PM, Richard V, Rasolofo Razanamparany V
PloS one 2015;10(7):e0127590
PloS one 2015;10(7):e0127590
Anti-hepatitis C virus T-cell immunity in the context of multiple exposures to the virus.
Pfafferott K, Deshpande P, McKinnon E, Merani S, Lucas A, Heckerman D, Mallal S, John M, Gaudieri S, Lucas M
PloS one 2015;10(6):e0130420
PloS one 2015;10(6):e0130420
The use of wavelength modulated Raman spectroscopy in label-free identification of T lymphocyte subsets, natural killer cells and dendritic cells.
Chen M, McReynolds N, Campbell EC, Mazilu M, Barbosa J, Dholakia K, Powis SJ
PloS one 2015;10(5):e0125158
PloS one 2015;10(5):e0125158
Determinants of vaccine immunogenicity in HIV-infected pregnant women: analysis of B and T cell responses to pandemic H1N1 monovalent vaccine.
Weinberg A, Muresan P, Richardson KM, Fenton T, Dominguez T, Bloom A, Watts DH, Abzug MJ, Nachman SA, Levin MJ, P1086 team
PloS one 2015;10(4):e0122431
PloS one 2015;10(4):e0122431
Viral infection of human lung macrophages increases PDL1 expression via IFNβ.
Staples KJ, Nicholas B, McKendry RT, Spalluto CM, Wallington JC, Bragg CW, Robinson EC, Martin K, Djukanović R, Wilkinson TM
PloS one 2015;10(3):e0121527
PloS one 2015;10(3):e0121527
Abacavir-reactive memory T cells are present in drug naïve individuals.
Lucas A, Lucas M, Strhyn A, Keane NM, McKinnon E, Pavlos R, Moran EM, Meyer-Pannwitt V, Gaudieri S, D'Orsogna L, Kalams S, Ostrov DA, Buus S, Peters B, Mallal S, Phillips E
PloS one 2015;10(2):e0117160
PloS one 2015;10(2):e0117160
Spontaneous Immunity Against the Receptor Tyrosine Kinase ROR1 in Patients with Chronic Lymphocytic Leukemia.
Hojjat-Farsangi M, Jeddi-Tehrani M, Daneshmanesh AH, Mozaffari F, Moshfegh A, Hansson L, Razavi SM, Sharifian RA, Rabbani H, Österborg A, Mellstedt H, Shokri F
PloS one 2015;10(11):e0142310
PloS one 2015;10(11):e0142310
Ratite oils promote keratinocyte cell growth and inhibit leukocyte activation.
Bennett DC, Leung G, Wang E, Ma S, Lo BK, McElwee KJ, Cheng KM
Poultry science 2015 Sep;94(9):2288-96
Poultry science 2015 Sep;94(9):2288-96
Phase I/II study of adjuvant immunotherapy with sentinel lymph node T lymphocytes in patients with colorectal cancer.
Zhen YH, Liu XH, Yang Y, Li B, Tang JL, Zeng QX, Hu J, Zeng XN, Zhang L, Wang ZJ, Li XY, Ge HX, Winqvist O, Hu PS, Xiu J
Cancer immunology, immunotherapy : CII 2015 Sep;64(9):1083-93
Cancer immunology, immunotherapy : CII 2015 Sep;64(9):1083-93
Characterization of amoxicillin- and clavulanic acid-specific T cells in patients with amoxicillin-clavulanate-induced liver injury.
Kim SH, Saide K, Farrell J, Faulkner L, Tailor A, Ogese M, Daly AK, Pirmohamed M, Park BK, Naisbitt DJ
Hepatology (Baltimore, Md.) 2015 Sep;62(3):887-99
Hepatology (Baltimore, Md.) 2015 Sep;62(3):887-99
Integration of humoral and cellular HLA-specific immune responses in cord blood allograft rejection.
Hanajiri R, Murata M, Sugimoto K, Murase M, Sakemura R, Goto T, Watanabe K, Imahashi N, Terakura S, Ohashi H, Akatsuka Y, Kurahashi S, Miyamura K, Kiyoi H, Nishida T, Naoe T
Bone marrow transplantation 2015 Sep;50(9):1187-94
Bone marrow transplantation 2015 Sep;50(9):1187-94
T-Regulatory Cells and Inflammatory and Inhibitory Cytokines in Malawian Children Residing in an Area of High and an Area of Low Malaria Transmission During Acute Uncomplicated Malaria and in Convalescence.
Nyirenda TS, Molyneux ME, Kenefeck R, Walker LS, MacLennan CA, Heyderman RS, Mandala WL
Journal of the Pediatric Infectious Diseases Society 2015 Sep;4(3):232-41
Journal of the Pediatric Infectious Diseases Society 2015 Sep;4(3):232-41
Thrombin may modulate dendritic cell activation in kidney transplant recipients with delayed graft function.
Pontrelli P, Cariello M, Rascio F, Gigante M, Verrienti R, Tataranni T, Castellano G, Divella C, Ranieri E, Stallone G, Gesualdo L, Grandaliano G
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2015 Sep;30(9):1480-7
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2015 Sep;30(9):1480-7
Exome Sequencing to Predict Neoantigens in Melanoma.
Pritchard AL, Burel JG, Neller MA, Hayward NK, Lopez JA, Fatho M, Lennerz V, Wölfel T, Schmidt CW
Cancer immunology research 2015 Sep;3(9):992-8
Cancer immunology research 2015 Sep;3(9):992-8
IL-35 inhibits HBV antigen-specific IFN-γ-producing CTLs in vitro.
Li X, Tian L, Dong Y, Zhu Q, Wang Y, Han W, Liu X, Ni Q, Chen Y, Li L
Clinical science (London, England : 1979) 2015 Sep;129(5):395-404
Clinical science (London, England : 1979) 2015 Sep;129(5):395-404
The antigenic landscape of multiple myeloma: mass spectrometry (re)defines targets for T-cell-based immunotherapy.
Walz S, Stickel JS, Kowalewski DJ, Schuster H, Weisel K, Backert L, Kahn S, Nelde A, Stroh T, Handel M, Kohlbacher O, Kanz L, Salih HR, Rammensee HG, Stevanović S
Blood 2015 Sep 3;126(10):1203-13
Blood 2015 Sep 3;126(10):1203-13
Immune Reconstitution After Allogeneic Hematopoietic Stem Cell Transplantation and Association With Occurrence and Outcome of Invasive Aspergillosis.
Stuehler C, Kuenzli E, Jaeger VK, Baettig V, Ferracin F, Rajacic Z, Kaiser D, Bernardini C, Forrer P, Weisser M, Elzi L, Battegay M, Halter J, Passweg J, Khanna N
The Journal of infectious diseases 2015 Sep 15;212(6):959-67
The Journal of infectious diseases 2015 Sep 15;212(6):959-67
Role of the 2B4 Receptor in CD8+ T-Cell-Dependent Immune Control of Epstein-Barr Virus Infection in Mice With Reconstituted Human Immune System Components.
Chijioke O, Marcenaro E, Moretta A, Capaul R, Münz C
The Journal of infectious diseases 2015 Sep 1;212(5):803-7
The Journal of infectious diseases 2015 Sep 1;212(5):803-7
T-Cell Responses Are Associated with Survival in Acute Melioidosis Patients.
Jenjaroen K, Chumseng S, Sumonwiriya M, Ariyaprasert P, Chantratita N, Sunyakumthorn P, Hongsuwan M, Wuthiekanun V, Fletcher HA, Teparrukkul P, Limmathurotsakul D, Day NP, Dunachie SJ
PLoS neglected tropical diseases 2015 Oct;9(10):e0004152
PLoS neglected tropical diseases 2015 Oct;9(10):e0004152
Innate Immune Activity Correlates with CD4 T Cell-Associated HIV-1 DNA Decline during Latency-Reversing Treatment with Panobinostat.
Olesen R, Vigano S, Rasmussen TA, Søgaard OS, Ouyang Z, Buzon M, Bashirova A, Carrington M, Palmer S, Brinkmann CR, Yu XG, Østergaard L, Tolstrup M, Lichterfeld M
Journal of virology 2015 Oct;89(20):10176-89
Journal of virology 2015 Oct;89(20):10176-89
Therapeutic bispecific T-cell engager antibody targeting the intracellular oncoprotein WT1.
Dao T, Pankov D, Scott A, Korontsvit T, Zakhaleva V, Xu Y, Xiang J, Yan S, de Morais Guerreiro MD, Veomett N, Dubrovsky L, Curcio M, Doubrovina E, Ponomarev V, Liu C, O'Reilly RJ, Scheinberg DA
Nature biotechnology 2015 Oct;33(10):1079-86
Nature biotechnology 2015 Oct;33(10):1079-86
Investigation of inflammatory profile in MSUD patients: benefit of L-carnitine supplementation.
Mescka CP, Guerreiro G, Donida B, Marchetti D, Wayhs CA, Ribas GS, Coitinho AS, Wajner M, Dutra-Filho CS, Vargas CR
Metabolic brain disease 2015 Oct;30(5):1167-74
Metabolic brain disease 2015 Oct;30(5):1167-74
Heteroclitic Peptides Increase Proliferation and Reduce Evidence of Human Immunodeficiency Virus-Specific CD8⁺ T Cell Dysfunction.
Adegoke A, Gladney K, Gallant M, Grant M
Viral immunology 2015 Oct;28(8):455-63
Viral immunology 2015 Oct;28(8):455-63
AZ17: a new bispecific drug targeting IL-6 and IL-23 with potential clinical use--improves psoriasis in a human xenograft transplantation model.
Stenderup K, Rosada C, Shanebeck K, Brady W, Van Brunt MP, King G, Marelli M, Slagle P, Xu H, Nairn NW, Johnson J, Wang AA, Li G, Thornton KC, Dam TN, Grabstein KH
Protein engineering, design & selection : PEDS 2015 Oct;28(10):467-80
Protein engineering, design & selection : PEDS 2015 Oct;28(10):467-80
Annexin A2 is a target of autoimmune T and B cell responses associated with synovial fibroblast proliferation in patients with antibiotic-refractory Lyme arthritis.
Pianta A, Drouin EE, Crowley JT, Arvikar S, Strle K, Costello CE, Steere AC
Clinical immunology (Orlando, Fla.) 2015 Oct;160(2):336-41
Clinical immunology (Orlando, Fla.) 2015 Oct;160(2):336-41
In Vitro Priming of Naı̈ve T-cells with p-Phenylenediamine and Bandrowski's Base.
Gibson A, Kim SH, Faulkner L, Evely J, Pirmohamed M, Park KB, Naisbitt DJ
Chemical research in toxicology 2015 Oct 19;28(10):2069-77
Chemical research in toxicology 2015 Oct 19;28(10):2069-77
Zoster Vaccination Increases the Breadth of CD4+ T Cells Responsive to Varicella Zoster Virus.
Laing KJ, Russell RM, Dong L, Schmid DS, Stern M, Magaret A, Haas JG, Johnston C, Wald A, Koelle DM
The Journal of infectious diseases 2015 Oct 1;212(7):1022-31
The Journal of infectious diseases 2015 Oct 1;212(7):1022-31
Gut commensal microbes do not represent a dominant antigenic source for continuous CD4+ T-cell activation during HIV-1 infection.
Zimmermann K, Bastidas S, Knecht L, Kuster H, Vavricka SR, Günthard HF, Oxenius A
European journal of immunology 2015 Nov;45(11):3107-13
European journal of immunology 2015 Nov;45(11):3107-13
Cytomegalovirus Encephalitis in a Patient with Severe Combined Immunodeficiency.
Motobayashi M, Shigemura T, Tanaka M, Kurata T, Kobayashi N, Agematsu K, Amano Y, Inaba Y, Koike K, Nakazawa Y
Journal of clinical immunology 2015 Nov;35(8):689-91
Journal of clinical immunology 2015 Nov;35(8):689-91
Long-term control of diabetes in immunosuppressed nonhuman primates (NHP) by the transplantation of adult porcine islets.
Shin JS, Kim JM, Kim JS, Min BH, Kim YH, Kim HJ, Jang JY, Yoon IH, Kang HJ, Kim J, Hwang ES, Lim DG, Lee WW, Ha J, Jung KC, Park SH, Kim SJ, Park CG
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2015 Nov;15(11):2837-50
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2015 Nov;15(11):2837-50
Identification of novel Lck-derived T helper epitope long peptides applicable for HLA-A2(+) cancer patients as cancer vaccine.
Matsueda S, Shichijo S, Nagata S, Seki C, Yamada A, Noguchi M, Itoh K
Cancer science 2015 Nov;106(11):1493-8
Cancer science 2015 Nov;106(11):1493-8
Identification of novel Mycobacterium tuberculosis CD4 T-cell antigens via high throughput proteome screening.
Nayak K, Jing L, Russell RM, Davies DH, Hermanson G, Molina DM, Liang X, Sherman DR, Kwok WW, Yang J, Kenneth J, Ahamed SF, Chandele A, Murali-Krishna K, Koelle DM
Tuberculosis (Edinburgh, Scotland) 2015 May;95(3):275-87
Tuberculosis (Edinburgh, Scotland) 2015 May;95(3):275-87
Transmitted/Founder Viruses Rapidly Escape from CD8+ T Cell Responses in Acute Hepatitis C Virus Infection.
Bull RA, Leung P, Gaudieri S, Deshpande P, Cameron B, Walker M, Chopra A, Lloyd AR, Luciani F
Journal of virology 2015 May;89(10):5478-90
Journal of virology 2015 May;89(10):5478-90
Clinical Control of HIV-1 by Cytotoxic T Cells Specific for Multiple Conserved Epitopes.
Murakoshi H, Akahoshi T, Koyanagi M, Chikata T, Naruto T, Maruyama R, Tamura Y, Ishizuka N, Gatanaga H, Oka S, Takiguchi M
Journal of virology 2015 May;89(10):5330-9
Journal of virology 2015 May;89(10):5330-9
Th22 cells increase in poor prognosis multiple myeloma and promote tumor cell growth and survival.
Di Lullo G, Marcatti M, Heltai S, Brunetto E, Tresoldi C, Bondanza A, Bonini C, Ponzoni M, Tonon G, Ciceri F, Bordignon C, Protti MP
Oncoimmunology 2015 May;4(5):e1005460
Oncoimmunology 2015 May;4(5):e1005460
Transitional B lymphocytes are associated with protection from kidney allograft rejection: a prospective study.
Shabir S, Girdlestone J, Briggs D, Kaul B, Smith H, Daga S, Chand S, Jham S, Navarrete C, Harper L, Ball S, Borrows R
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2015 May;15(5):1384-91
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2015 May;15(5):1384-91
Antibody and T-cell responses associated with experimental human malaria infection or vaccination show limited relationships.
Walker KM, Okitsu S, Porter DW, Duncan C, Amacker M, Pluschke G, Cavanagh DR, Hill AV, Todryk SM
Immunology 2015 May;145(1):71-81
Immunology 2015 May;145(1):71-81
Anti-HER2 CD4(+) T-helper type 1 response is a novel immune correlate to pathologic response following neoadjuvant therapy in HER2-positive breast cancer.
Datta J, Berk E, Xu S, Fitzpatrick E, Rosemblit C, Lowenfeld L, Goodman N, Lewis DA, Zhang PJ, Fisher C, Roses RE, DeMichele A, Czerniecki BJ
Breast cancer research : BCR 2015 May 23;17(1):71
Breast cancer research : BCR 2015 May 23;17(1):71
Tumor-infiltrating lymphocyte activity is enhanced in tumors with low IL-10 production in HBV-induced hepatocellular carcinoma.
Shi Y, Song Q, Hu D, Zhuang X, Yu S
Biochemical and biophysical research communications 2015 May 22;461(1):109-14
Biochemical and biophysical research communications 2015 May 22;461(1):109-14
Longevity of B-cell and T-cell responses after live attenuated influenza vaccination in children.
Mohn KG, Bredholt G, Brokstad KA, Pathirana RD, Aarstad HJ, Tøndel C, Cox RJ
The Journal of infectious diseases 2015 May 15;211(10):1541-9
The Journal of infectious diseases 2015 May 15;211(10):1541-9
T Cell Immunity to the Alkyl Hydroperoxide Reductase of Burkholderia pseudomallei: A Correlate of Disease Outcome in Acute Melioidosis.
Reynolds C, Goudet A, Jenjaroen K, Sumonwiriya M, Rinchai D, Musson J, Overbeek S, Makinde J, Quigley K, Manji J, Spink N, Yos P, Wuthiekanun V, Bancroft G, Robinson J, Lertmemongkolchai G, Dunachie S, Maillere B, Holden M, Altmann D, Boyton R
Journal of immunology (Baltimore, Md. : 1950) 2015 May 15;194(10):4814-24
Journal of immunology (Baltimore, Md. : 1950) 2015 May 15;194(10):4814-24
Complete regression of metastatic cervical cancer after treatment with human papillomavirus-targeted tumor-infiltrating T cells.
Stevanović S, Draper LM, Langhan MM, Campbell TE, Kwong ML, Wunderlich JR, Dudley ME, Yang JC, Sherry RM, Kammula US, Restifo NP, Rosenberg SA, Hinrichs CS
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2015 May 10;33(14):1543-50
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2015 May 10;33(14):1543-50
Mapping the HLA ligandome landscape of acute myeloid leukemia: a targeted approach toward peptide-based immunotherapy.
Berlin C, Kowalewski DJ, Schuster H, Mirza N, Walz S, Handel M, Schmid-Horch B, Salih HR, Kanz L, Rammensee HG, Stevanović S, Stickel JS
Leukemia 2015 Mar;29(3):647-59
Leukemia 2015 Mar;29(3):647-59
Safety and tolerability of allogeneic dendritic cell vaccination with induction of Wilms tumor 1-specific T cells in a pediatric donor and pediatric patient with relapsed leukemia: a case report and review of the literature.
Saito S, Yanagisawa R, Yoshikawa K, Higuchi Y, Koya T, Yoshizawa K, Tanaka M, Sakashita K, Kobayashi T, Kurata T, Hirabayashi K, Nakazawa Y, Shiohara M, Yonemitsu Y, Okamoto M, Sugiyama H, Koike K, Shimodaira S
Cytotherapy 2015 Mar;17(3):330-5
Cytotherapy 2015 Mar;17(3):330-5
Alternative effector-function profiling identifies broad HIV-specific T-cell responses in highly HIV-exposed individuals who remain uninfected.
Ruiz-Riol M, Llano A, Ibarrondo J, Zamarreño J, Yusim K, Bach V, Mothe B, Perez-Alvarez S, Fernandez MA, Requena G, Meulbroek M, Pujol F, Leon A, Cobarsi P, Korber BT, Clotet B, Ganoza C, Sanchez J, Coll J, Brander C
The Journal of infectious diseases 2015 Mar 15;211(6):936-46
The Journal of infectious diseases 2015 Mar 15;211(6):936-46
Early Kinetics of the HLA Class I-Associated Peptidome of MVA.HIVconsv-Infected Cells.
Ternette N, Block PD, Sánchez-Bernabéu Á, Borthwick N, Pappalardo E, Abdul-Jawad S, Ondondo B, Charles PD, Dorrell L, Kessler BM, Hanke T
Journal of virology 2015 Jun;89(11):5760-71
Journal of virology 2015 Jun;89(11):5760-71
Differences in immune responses between CMV-seronegative and -seropositive patients with myocardial ischemia and reperfusion.
Shmeleva EV, Boag SE, Murali S, Bennaceur K, Das R, Egred M, Purcell I, Edwards R, Todryk S, Spyridopoulos I
Immunity, inflammation and disease 2015 Jun;3(2):56-70
Immunity, inflammation and disease 2015 Jun;3(2):56-70
Kinetics and Immunodominance of Virus-Specific T Cell Responses During Hantaan Virus Infection.
Wang M, Wang J, Kang Z, Zhao Q, Wang X, Hui L
Viral immunology 2015 Jun;28(5):265-71
Viral immunology 2015 Jun;28(5):265-71
Aging influences the response of T cells to stimulation by the ellagitannin, oenothein B.
Ramstead AG, Schepetkin IA, Todd K, Loeffelholz J, Berardinelli JG, Quinn MT, Jutila MA
International immunopharmacology 2015 Jun;26(2):367-77
International immunopharmacology 2015 Jun;26(2):367-77
Maternal plasma and breastmilk viral loads are associated with HIV-1-specific cellular immune responses among HIV-1-exposed, uninfected infants in Kenya.
Liu AY, Lohman-Payne B, Chung MH, Kiarie J, Kinuthia J, Slyker J, Richardson B, Lehman D, Farquhar C, John-Stewart G
Clinical and experimental immunology 2015 Jun;180(3):509-19
Clinical and experimental immunology 2015 Jun;180(3):509-19
Gastrointestinal immunity against tryptophan hydroxylase-1, aromatic L-amino-acid decarboxylase, AIE-75, villin and Paneth cells in APECED.
Kluger N, Jokinen M, Lintulahti A, Krohn K, Ranki A
Clinical immunology (Orlando, Fla.) 2015 Jun;158(2):212-20
Clinical immunology (Orlando, Fla.) 2015 Jun;158(2):212-20
Generation of TCR-engineered T cells and their use to control the performance of T cell assays.
Bidmon N, Attig S, Rae R, Schröder H, Omokoko TA, Simon P, Kuhn AN, Kreiter S, Sahin U, Gouttefangeas C, van der Burg SH, Britten CM
Journal of immunology (Baltimore, Md. : 1950) 2015 Jun 15;194(12):6177-89
Journal of immunology (Baltimore, Md. : 1950) 2015 Jun 15;194(12):6177-89
WT1 vaccination in AML and MDS: A pilot trial with synthetic analog peptides.
Brayer J, Lancet JE, Powers J, List A, Balducci L, Komrokji R, Pinilla-Ibarz J
American journal of hematology 2015 Jul;90(7):602-7
American journal of hematology 2015 Jul;90(7):602-7
The Epstein-Barr Virus Lytic Protein BZLF1 as a Candidate Target Antigen for Vaccine Development.
Hartlage AS, Liu T, Patton JT, Garman SL, Zhang X, Kurt H, Lozanski G, Lustberg ME, Caligiuri MA, Baiocchi RA
Cancer immunology research 2015 Jul;3(7):787-94
Cancer immunology research 2015 Jul;3(7):787-94
Generation of tumor-specific cytotoxic T-lymphocytes from the peripheral blood of colorectal cancer patients for adoptive T-cell transfer.
Carluccio S, Delbue S, Signorini L, Setola E, Bagliani A, Della Valle A, Galli A, Ferrante P, Bregni M
Journal of cellular physiology 2015 Jul;230(7):1457-65
Journal of cellular physiology 2015 Jul;230(7):1457-65
A Synthetic Influenza Virus Vaccine Induces a Cellular Immune Response That Correlates with Reduction in Symptomatology and Virus Shedding in a Randomized Phase Ib Live-Virus Challenge in Humans.
Pleguezuelos O, Robinson S, Fernández A, Stoloff GA, Mann A, Gilbert A, Balaratnam G, Wilkinson T, Lambkin-Williams R, Oxford J, Caparrós-Wanderley W
Clinical and vaccine immunology : CVI 2015 Jul;22(7):828-35
Clinical and vaccine immunology : CVI 2015 Jul;22(7):828-35
Mycobacterium bovis BCG Vaccination Induces Divergent Proinflammatory or Regulatory T Cell Responses in Adults.
Boer MC, Prins C, van Meijgaarden KE, van Dissel JT, Ottenhoff TH, Joosten SA
Clinical and vaccine immunology : CVI 2015 Jul;22(7):778-88
Clinical and vaccine immunology : CVI 2015 Jul;22(7):778-88
Bifidobacteria Enhance Antigen Sampling and Processing by Dendritic Cells in Pediatric Inflammatory Bowel Disease.
Strisciuglio C, Miele E, Giugliano FP, Vitale S, Andreozzi M, Vitale A, Catania MR, Staiano A, Troncone R, Gianfrani C
Inflammatory bowel diseases 2015 Jul;21(7):1491-8
Inflammatory bowel diseases 2015 Jul;21(7):1491-8
Identification of autoreactive CD8+ T cell responses targeting chromogranin A in humanized NOD mice and type 1 diabetes patients.
Li Y, Zhou L, Li Y, Zhang J, Guo B, Meng G, Chen X, Zheng Q, Zhang L, Zhang M, Wang L
Clinical immunology (Orlando, Fla.) 2015 Jul;159(1):63-71
Clinical immunology (Orlando, Fla.) 2015 Jul;159(1):63-71
Detection of HIV-1-specific T-cell immune responses in highly HIV-exposed uninfected individuals by in-vitro dendritic cell co-culture.
Guardo AC, Ruiz-Riol M, Fernández E, Maleno MJ, Bargalló ME, León A, Climent N, García F, Gatell JM, Brander C, Plana M
AIDS (London, England) 2015 Jul 17;29(11):1309-18
AIDS (London, England) 2015 Jul 17;29(11):1309-18
T cell epitope clustering in the highly immunogenic BZLF1 antigen of Epstein-Barr virus.
Rist MJ, Neller MA, Burrows JM, Burrows SR
Journal of virology 2015 Jan;89(1):703-12
Journal of virology 2015 Jan;89(1):703-12
Ingestion of oats and barley in patients with celiac disease mobilizes cross-reactive T cells activated by avenin peptides and immuno-dominant hordein peptides.
Hardy MY, Tye-Din JA, Stewart JA, Schmitz F, Dudek NL, Hanchapola I, Purcell AW, Anderson RP
Journal of autoimmunity 2015 Jan;56:56-65
Journal of autoimmunity 2015 Jan;56:56-65
Cellular immune response following pre-exposure and postexposure rabies vaccination by intradermal and intramuscular routes.
Venkataswamy MM, Madhusudana SN, Sanyal SS, Taj S, Belludi AY, Mani RS, Hazra N
Clinical and experimental vaccine research 2015 Jan;4(1):68-74
Clinical and experimental vaccine research 2015 Jan;4(1):68-74
Immunity to the vacuolar ATPase complex accessory unit ATP6S1 in patients with malignant melanoma.
Zhou J, Gupta M, Wu X, Yoon C, Giobbie-Hurder A, Hodi FS
Cancer immunology research 2015 Jan;3(1):59-67
Cancer immunology research 2015 Jan;3(1):59-67
Reactivity against microsatellite instability-induced frameshift mutations in patients with inflammatory bowel disease.
Kuehn F, Klar E, Bliemeister A, Linnebacher M
World journal of gastroenterology 2015 Jan 7;21(1):221-8
World journal of gastroenterology 2015 Jan 7;21(1):221-8
Myocardial ischemia and reperfusion leads to transient CD8 immune deficiency and accelerated immunosenescence in CMV-seropositive patients.
Hoffmann J, Shmeleva EV, Boag SE, Fiser K, Bagnall A, Murali S, Dimmick I, Pircher H, Martin-Ruiz C, Egred M, Keavney B, von Zglinicki T, Das R, Todryk S, Spyridopoulos I
Circulation research 2015 Jan 2;116(1):87-98
Circulation research 2015 Jan 2;116(1):87-98
Phase II clinical trial of multiple peptide vaccination for advanced head and neck cancer patients revealed induction of immune responses and improved OS.
Yoshitake Y, Fukuma D, Yuno A, Hirayama M, Nakayama H, Tanaka T, Nagata M, Takamune Y, Kawahara K, Nakagawa Y, Yoshida R, Hirosue A, Ogi H, Hiraki A, Jono H, Hamada A, Yoshida K, Nishimura Y, Nakamura Y, Shinohara M
Clinical cancer research : an official journal of the American Association for Cancer Research 2015 Jan 15;21(2):312-21
Clinical cancer research : an official journal of the American Association for Cancer Research 2015 Jan 15;21(2):312-21
Identification of promiscuous HPV16-derived T helper cell epitopes for therapeutic HPV vaccine design.
Grabowska AK, Kaufmann AM, Riemer AB
International journal of cancer 2015 Jan 1;136(1):212-24
International journal of cancer 2015 Jan 1;136(1):212-24
Characterisation of the cytokine milieu associated with the up-regulation of IL-6 and suppressor of cytokine 3 in chronic hepatitis C treatment non-responders.
Martinez D, Palmer C, Simar D, Cameron BA, Nguyen N, Aggarwal V, Lloyd AR, Zekry A
Liver international : official journal of the International Association for the Study of the Liver 2015 Feb;35(2):463-72
Liver international : official journal of the International Association for the Study of the Liver 2015 Feb;35(2):463-72
Broadly-specific cytotoxic T cells targeting multiple HIV antigens are expanded from HIV+ patients: implications for immunotherapy.
Lam S, Sung J, Cruz C, Castillo-Caro P, Ngo M, Garrido C, Kuruc J, Archin N, Rooney C, Margolis D, Bollard C
Molecular therapy : the journal of the American Society of Gene Therapy 2015 Feb;23(2):387-95
Molecular therapy : the journal of the American Society of Gene Therapy 2015 Feb;23(2):387-95
Effects of antiviral therapy on the cellular immune response in patients with chronic hepatitis B.
Luo G, Feng X, Huang Y, Yi T, Wang D, Guo X, Yan H, Zhang G
Molecular medicine reports 2015 Feb;11(2):1284-91
Molecular medicine reports 2015 Feb;11(2):1284-91
Bee venom processes human skin lipids for presentation by CD1a.
Bourgeois EA, Subramaniam S, Cheng TY, De Jong A, Layre E, Ly D, Salimi M, Legaspi A, Modlin RL, Salio M, Cerundolo V, Moody DB, Ogg G
The Journal of experimental medicine 2015 Feb 9;212(2):149-63
The Journal of experimental medicine 2015 Feb 9;212(2):149-63
Safety and immunogenicity of DNA vaccines encoding Ebolavirus and Marburgvirus wild-type glycoproteins in a phase I clinical trial.
Sarwar UN, Costner P, Enama ME, Berkowitz N, Hu Z, Hendel CS, Sitar S, Plummer S, Mulangu S, Bailer RT, Koup RA, Mascola JR, Nabel GJ, Sullivan NJ, Graham BS, Ledgerwood JE, VRC 206 Study Team
The Journal of infectious diseases 2015 Feb 15;211(4):549-57
The Journal of infectious diseases 2015 Feb 15;211(4):549-57
A side-by-side comparison of T cell reactivity to fifty-nine Mycobacterium tuberculosis antigens in diverse populations from five continents.
Carpenter C, Sidney J, Kolla R, Nayak K, Tomiyama H, Tomiyama C, Padilla OA, Rozot V, Ahamed SF, Ponte C, Rolla V, Antas PR, Chandele A, Kenneth J, Laxmi S, Makgotlho E, Vanini V, Ippolito G, Kazanova AS, Panteleev AV, Hanekom W, Mayanja-Kizza H, Lewinsohn D, Saito M, McElrath MJ, Boom WH, Goletti D, Gilman R, Lyadova IV, Scriba TJ, Kallas EG, Murali-Krishna K, Sette A, Lindestam Arlehamn CS
Tuberculosis (Edinburgh, Scotland) 2015 Dec;95(6):713-721
Tuberculosis (Edinburgh, Scotland) 2015 Dec;95(6):713-721
T- and B-cell responses and previous exposure to hepatitis B virus in 'anti-HBc alone' patients.
Wang Q, Sachse P, Semmo M, Lokhande M, Montani M, Dufour JF, Zoulim F, Klenerman P, Semmo N
Journal of viral hepatitis 2015 Dec;22(12):1068-78
Journal of viral hepatitis 2015 Dec;22(12):1068-78
Recombinant Immunotoxin with T-cell Epitope Mutations That Greatly Reduce Immunogenicity for Treatment of Mesothelin-Expressing Tumors.
Mazor R, Zhang J, Xiang L, Addissie S, Awuah P, Beers R, Hassan R, Pastan I
Molecular cancer therapeutics 2015 Dec;14(12):2789-96
Molecular cancer therapeutics 2015 Dec;14(12):2789-96
Melanocyte antigen triggers autoimmunity in human psoriasis.
Arakawa A, Siewert K, Stöhr J, Besgen P, Kim SM, Rühl G, Nickel J, Vollmer S, Thomas P, Krebs S, Pinkert S, Spannagl M, Held K, Kammerbauer C, Besch R, Dornmair K, Prinz JC
The Journal of experimental medicine 2015 Dec 14;212(13):2203-12
The Journal of experimental medicine 2015 Dec 14;212(13):2203-12
A Highly Expressed Human Protein, Apolipoprotein B-100, Serves as an Autoantigen in a Subgroup of Patients With Lyme Disease.
Crowley JT, Drouin EE, Pianta A, Strle K, Wang Q, Costello CE, Steere AC
The Journal of infectious diseases 2015 Dec 1;212(11):1841-50
The Journal of infectious diseases 2015 Dec 1;212(11):1841-50
Human papillomavirus-exposed Langerhans cells are activated by stabilized Poly-I:C.
Da Silva DM, Woodham AW, Rijkee LK, Skeate JG, Taylor JR, Koopman ME, Brand HE, Wong MK, McKee GM, Salazar AM, Kast WM
Papillomavirus research (Amsterdam, Netherlands) 2015 Dec 1;1:12-21
Papillomavirus research (Amsterdam, Netherlands) 2015 Dec 1;1:12-21
Immune responses to latent tuberculosis antigen Rv2659c in Chinese populations.
Bai XJ, Liang Y, Yang YR, Li N, Zhang XY, An HR, Zhang JX, Chen D, Wang L, Wu XQ
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 2015 Aug;48(4):381-9
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 2015 Aug;48(4):381-9
Oral administration of non-absorbable delayed release 6-mercaptopurine is locally active in the gut, exerts a systemic immune effect and alleviates Crohn's disease with low rate of side effects: results of double blind Phase II clinical trial.
Israeli E, Goldin E, Fishman S, Konikoff F, Lavy A, Chowers Y, Melzer E, Lahat A, Mahamid M, Shirin H, Nussinson E, Segol O, Ya'acov AB, Shabbat Y, Ilan Y
Clinical and experimental immunology 2015 Aug;181(2):362-72
Clinical and experimental immunology 2015 Aug;181(2):362-72
Cross-Reactivity Between Influenza Matrix- and HIV-1 P17-Specific CTL-A Large Cohort Study.
Hückelhoven AG, Etschel JK, Bergmann S, Zitzelsberger K, Mueller-Schmucker SM, Harrer EG, Harrer T
Journal of acquired immune deficiency syndromes (1999) 2015 Aug 15;69(5):528-35
Journal of acquired immune deficiency syndromes (1999) 2015 Aug 15;69(5):528-35
The Tumor Antigen Cyclin B1 Hosts Multiple CD4 T Cell Epitopes Differently Recognized by Pre-Existing Naive and Memory Cells in Both Healthy and Cancer Donors.
Chevaleyre C, Benhamouda N, Favry E, Fabre E, Mhoumadi A, Nozach H, Marcon E, Cosler G, Vinatier E, Oudard S, Hans S, Le Pimpec-Barthes F, Bats AS, Castelli FA, Tartour E, Maillère B
Journal of immunology (Baltimore, Md. : 1950) 2015 Aug 15;195(4):1891-901
Journal of immunology (Baltimore, Md. : 1950) 2015 Aug 15;195(4):1891-901
Langerhans Cell-Dendritic Cell Cross-Talk via Langerin and Hyaluronic Acid Mediates Antigen Transfer and Cross-Presentation of HIV-1.
van den Berg LM, Cardinaud S, van der Aar AM, Sprokholt JK, de Jong MA, Zijlstra-Willems EM, Moris A, Geijtenbeek TB
Journal of immunology (Baltimore, Md. : 1950) 2015 Aug 15;195(4):1763-73
Journal of immunology (Baltimore, Md. : 1950) 2015 Aug 15;195(4):1763-73
IL-15 induces strong but short-lived tumor-infiltrating CD8 T cell responses through the regulation of Tim-3 in breast cancer.
Heon EK, Wulan H, Macdonald LP, Malek AO, Braunstein GH, Eaves CG, Schattner MD, Allen PM, Alexander MO, Hawkins CA, McGovern DW, Freeman RL, Amir EP, Huse JD, Zaltzman JS, Kauff NP, Meyers PG, Gleason MH, Overholtzer MG, Wiseman SS, Streutker CD, Asa SW, McAlindon TP, Newcomb PO, Sorensen PM, Press OA
Biochemical and biophysical research communications 2015 Aug 14;464(1):360-6
Biochemical and biophysical research communications 2015 Aug 14;464(1):360-6
Functionality of dengue virus specific memory T cell responses in individuals who were hospitalized or who had mild or subclinical dengue infection.
Jeewandara C, Adikari TN, Gomes L, Fernando S, Fernando RH, Perera MK, Ariyaratne D, Kamaladasa A, Salimi M, Prathapan S, Ogg GS, Malavige GN
PLoS neglected tropical diseases 2015 Apr;9(4):e0003673
PLoS neglected tropical diseases 2015 Apr;9(4):e0003673
A high-throughput RNAi screen for detection of immune-checkpoint molecules that mediate tumor resistance to cytotoxic T lymphocytes.
Khandelwal N, Breinig M, Speck T, Michels T, Kreutzer C, Sorrentino A, Sharma AK, Umansky L, Conrad H, Poschke I, Offringa R, König R, Bernhard H, Machlenkin A, Boutros M, Beckhove P
EMBO molecular medicine 2015 Apr;7(4):450-63
EMBO molecular medicine 2015 Apr;7(4):450-63
Cytokine-induced killer cells engineered with exogenous T-cell receptors directed against melanoma antigens: enhanced efficacy of effector cells endowed with a double mechanism of tumor recognition.
Elia AR, Circosta P, Sangiolo D, Bonini C, Gammaitoni L, Mastaglio S, Genovese P, Geuna M, Avolio F, Inghirami G, Tarella C, Cignetti A
Human gene therapy 2015 Apr;26(4):220-31
Human gene therapy 2015 Apr;26(4):220-31
Antigen-induced regulation of T-cell motility, interaction with antigen-presenting cells and activation through endogenous thrombospondin-1 and its receptors.
Bergström SE, Uzunel M, Talme T, Bergdahl E, Sundqvist KG
Immunology 2015 Apr;144(4):687-703
Immunology 2015 Apr;144(4):687-703
Assessing the prognostic value of preoperative carcinoembryonic antigen-specific T-cell responses in colorectal cancer.
Scurr MJ, Brown CM, Costa Bento DF, Betts GJ, Rees BI, Hills RK, Gallimore A, Godkin A
Journal of the National Cancer Institute 2015 Apr;107(4)
Journal of the National Cancer Institute 2015 Apr;107(4)
Optimal PEGylation can improve the exposure of interferon in the lungs following pulmonary administration.
Mcleod VM, Chan LJ, Ryan GM, Porter CJ, Kaminskas LM
Journal of pharmaceutical sciences 2015 Apr;104(4):1421-30
Journal of pharmaceutical sciences 2015 Apr;104(4):1421-30
Correction: Santos, R.S., et al. Improvement of IFNγ ELISPOT Performance Following Overnight Resting of Frozen PBMC Samples Confirmed Through Rigorous Statistical Analysis. Cells 2015, 4, 1-18.
Santos R, Buying A, Sabri N, Yu J, Gringeri A, Bender J, Janetzki S, Pinilla C, Judkowski VA
Cells 2015 Apr 21;4(2):133-4
Cells 2015 Apr 21;4(2):133-4
Analysis of protein kinase C theta inhibitors for the control of HIV-1 replication in human CD4+ T cells reveals an effect on retrotranscription in addition to viral transcription.
Bermejo M, López-Huertas MR, Hedgpeth J, Mateos E, Rodríguez-Mora S, Maleno MJ, Plana M, Swindle J, Alcamí J, Coiras M
Biochemical pharmacology 2015 Apr 15;94(4):241-56
Biochemical pharmacology 2015 Apr 15;94(4):241-56
Association of antigen-specific T-cell responses with antigen expression and immunoparalysis in multiple myeloma.
Fichtner S, Hose D, Engelhardt M, Meißner T, Neuber B, Krasniqi F, Raab M, Schönland S, Ho AD, Goldschmidt H, Hundemer M
Clinical cancer research : an official journal of the American Association for Cancer Research 2015 Apr 1;21(7):1712-21
Clinical cancer research : an official journal of the American Association for Cancer Research 2015 Apr 1;21(7):1712-21
Incomplete recovery of pneumococcal CD4 T cell immunity after initiation of antiretroviral therapy in HIV-infected malawian adults.
Sepako E, Glennie SJ, Jambo KC, Mzinza D, Iwajomo OH, Banda D, van Oosterhout JJ, A Williams N, Gordon SB, Heyderman RS
PloS one 2014;9(6):e100640
PloS one 2014;9(6):e100640
Novel approach to activity evaluation for release-active forms of anti-interferon-gamma antibodies based on enzyme-linked immunoassay.
Gavrilova ES, Bobrovnik SA, Sherriff G, Myslivets AA, Tarasov SA, Epstein OI
PloS one 2014;9(5):e97017
PloS one 2014;9(5):e97017
Identification and HLA-tetramer-validation of human CD4+ and CD8+ T cell responses against HCMV proteins IE1 and IE2.
Braendstrup P, Mortensen BK, Justesen S, Osterby T, Rasmussen M, Hansen AM, Christiansen CB, Hansen MB, Nielsen M, Vindeløv L, Buus S, Stryhn A
PloS one 2014;9(4):e94892
PloS one 2014;9(4):e94892
The effect of maternal helminth infection on maternal and neonatal immune function and immunity to tuberculosis.
Gebreegziabiher D, Desta K, Desalegn G, Howe R, Abebe M
PloS one 2014;9(4):e93429
PloS one 2014;9(4):e93429
The candidate TB vaccine, MVA85A, induces highly durable Th1 responses.
Tameris M, Geldenhuys H, Luabeya AK, Smit E, Hughes JE, Vermaak S, Hanekom WA, Hatherill M, Mahomed H, McShane H, Scriba TJ
PloS one 2014;9(2):e87340
PloS one 2014;9(2):e87340
Safety and comparability of controlled human Plasmodium falciparum infection by mosquito bite in malaria-naïve subjects at a new facility for sporozoite challenge.
Talley AK, Healy SA, Finney OC, Murphy SC, Kublin J, Salas CJ, Lundebjerg S, Gilbert P, Van Voorhis WC, Whisler J, Wang R, Ockenhouse CF, Heppner DG, Kappe SH, Duffy PE
PloS one 2014;9(11):e109654
PloS one 2014;9(11):e109654
Neonatal BCG vaccination is associated with enhanced T-helper 1 immune responses to heterologous infant vaccines.
Libraty DH, Zhang L, Woda M, Acosta LP, Obcena A, Brion JD, Capeding RZ
Trials in vaccinology 2014;3:1-5
Trials in vaccinology 2014;3:1-5
The effect of in vivo exposure to zearalenone on cytokine secretion by Th1 and Th2 lymphocytes in porcine Peyer's patches after in vitro stimulation with LPS.
Obremski K
Polish journal of veterinary sciences 2014;17(4):625-32
Polish journal of veterinary sciences 2014;17(4):625-32
Greater frequency of CD5-negative CD8(+) T cells against human immunodeficiency virus type 1 than other viruses is consistent with adaptation to antigenic variation.
Penney SJ, Gallant ME, Grant MD
AIDS research and therapy 2014;11:30
AIDS research and therapy 2014;11:30
Cell-mediated immune responses to respiratory syncytial virus infection: magnitude, kinetics, and correlates with morbidity and age.
Geevarghese B, Weinberg A
Human vaccines & immunotherapeutics 2014;10(4):1047-56
Human vaccines & immunotherapeutics 2014;10(4):1047-56
Clinical validation of IFNγ/IL-10 and IFNγ/IL-2 FluoroSpot assays for the detection of Tr1 T cells and influenza vaccine monitoring in humans.
Chauvat A, Benhamouda N, Gey A, Lemoine FM, Paulie S, Carrat F, Gougeon ML, Rozenberg F, Krivine A, Cherai M, Lehmann P 5th, Quintin-Colonna F, Launay O, Tartour E
Human vaccines & immunotherapeutics 2014;10(1):104-13
Human vaccines & immunotherapeutics 2014;10(1):104-13
A Human Papillomavirus Type 16 E6 52-62 CD4 T-Cell Epitope Restricted by the HLA-DR11 Molecule Described in an Epitope Hotspot.
Coleman HN, Wang X, Greenfield WW, Nakagawa M
MOJ immunology 2014;1(3)
MOJ immunology 2014;1(3)
Involvement of PIT-1-reactive cytotoxic T lymphocytes in anti-PIT-1 antibody syndrome.
Bando H, Iguchi G, Fukuoka H, Yamamoto M, Hidaka-Takeno R, Okimura Y, Matsumoto R, Suda K, Nishizawa H, Takahashi M, Tojo K, Takahashi Y
The Journal of clinical endocrinology and metabolism 2014 Sep;99(9):E1744-9
The Journal of clinical endocrinology and metabolism 2014 Sep;99(9):E1744-9
Telomerase (GV1001) vaccination together with gemcitabine in advanced pancreatic cancer patients.
Staff C, Mozaffari F, Frödin JE, Mellstedt H, Liljefors M
International journal of oncology 2014 Sep;45(3):1293-303
International journal of oncology 2014 Sep;45(3):1293-303
Acute respiratory failure secondary to eosinophilic pneumonia following influenza vaccination in an elderly man with chronic obstructive pulmonary disease.
Pornsuriyasak P, Suwatanapongched T, Klaewsongkram J, Buranapraditkun S, Rotjanapan P
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 2014 Sep;26:14-6
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 2014 Sep;26:14-6
Nanogel-based immunologically stealth vaccine targets macrophages in the medulla of lymph node and induces potent antitumor immunity.
Muraoka D, Harada N, Hayashi T, Tahara Y, Momose F, Sawada S, Mukai SA, Akiyoshi K, Shiku H
ACS nano 2014 Sep 23;8(9):9209-18
ACS nano 2014 Sep 23;8(9):9209-18
High frequency of cytolytic 21-hydroxylase-specific CD8+ T cells in autoimmune Addison's disease patients.
Dawoodji A, Chen JL, Shepherd D, Dalin F, Tarlton A, Alimohammadi M, Penna-Martinez M, Meyer G, Mitchell AL, Gan EH, Bratland E, Bensing S, Husebye ES, Pearce SH, Badenhoop K, Kämpe O, Cerundolo V
Journal of immunology (Baltimore, Md. : 1950) 2014 Sep 1;193(5):2118-26
Journal of immunology (Baltimore, Md. : 1950) 2014 Sep 1;193(5):2118-26
The cytokine production of peripheral blood mononuclear cells reflects the autoantibody profile of patients suffering from type 1 diabetes.
Labikova J, Vcelakova J, Ulmannova T, Petruzelkova L, Kolouskova S, Stechova K
Cytokine 2014 Oct;69(2):189-95
Cytokine 2014 Oct;69(2):189-95
Common Ewing sarcoma-associated antigens fail to induce natural T cell responses in both patients and healthy individuals.
Altvater B, Kailayangiri S, Theimann N, Ahlmann M, Farwick N, Chen C, Pscherer S, Neumann I, Mrachatz G, Hansmeier A, Hardes J, Gosheger G, Juergens H, Rossig C
Cancer immunology, immunotherapy : CII 2014 Oct;63(10):1047-60
Cancer immunology, immunotherapy : CII 2014 Oct;63(10):1047-60
Protection against hepatitis C infection via NK cells in highly-exposed uninfected injecting drug users.
Sugden PB, Cameron B, Mina M, Lloyd AR, HITS investigators
Journal of hepatology 2014 Oct;61(4):738-45
Journal of hepatology 2014 Oct;61(4):738-45
Early initiation of combination antiretroviral therapy in HIV-1-infected newborns can achieve sustained virologic suppression with low frequency of CD4+ T cells carrying HIV in peripheral blood.
Bitnun A, Samson L, Chun TW, Kakkar F, Brophy J, Murray D, Justement S, Soudeyns H, Ostrowski M, Mujib S, Harrigan PR, Kim J, Sandstrom P, Read SE
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2014 Oct;59(7):1012-9
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2014 Oct;59(7):1012-9
Blood dendritic cell levels associated with impaired IL-12 production and T-cell deficiency in patients with kidney disease: implications for post-transplant viral infections.
Chen P, Sun Q, Huang Y, Atta MG, Turban S, Segev DL, Marr KA, Naqvi FF, Alachkar N, Kraus ES, Womer KL
Transplant international : official journal of the European Society for Organ Transplantation 2014 Oct;27(10):1069-76
Transplant international : official journal of the European Society for Organ Transplantation 2014 Oct;27(10):1069-76
Dynamics of T-cell IFN-γ and miR-29a expression during active pulmonary tuberculosis.
Afum-Adjei Awuah A, Ueberberg B, Owusu-Dabo E, Frempong M, Jacobsen M
International immunology 2014 Oct;26(10):579-82
International immunology 2014 Oct;26(10):579-82
Hydrogen peroxide inactivation of influenza virus preserves antigenic structure and immunogenicity.
Dembinski JL, Hungnes O, Hauge AG, Kristoffersen AC, Haneberg B, Mjaaland S
Journal of virological methods 2014 Oct;207:232-7
Journal of virological methods 2014 Oct;207:232-7
Health maintenance and inflammatory bowel disease.
Manolakis CS, Cash BD
Current gastroenterology reports 2014 Oct;16(10):402
Current gastroenterology reports 2014 Oct;16(10):402
Identification and translational validation of novel mammaglobin-A CD8 T cell epitopes.
Soysal SD, Muenst S, Kan-Mitchell J, Huarte E, Zhang X, Wilkinson-Ryan I, Fleming T, Tiriveedhi V, Mohanakumar T, Li L, Herndon J, Oertli D, Goedegebuure SP, Gillanders WE
Breast cancer research and treatment 2014 Oct;147(3):527-37
Breast cancer research and treatment 2014 Oct;147(3):527-37
Oral vaccination against HPV E7 for treatment of cervical intraepithelial neoplasia grade 3 (CIN3) elicits E7-specific mucosal immunity in the cervix of CIN3 patients.
Kawana K, Adachi K, Kojima S, Taguchi A, Tomio K, Yamashita A, Nishida H, Nagasaka K, Arimoto T, Yokoyama T, Wada-Hiraike O, Oda K, Sewaki T, Osuga Y, Fujii T
Vaccine 2014 Oct 29;32(47):6233-9
Vaccine 2014 Oct 29;32(47):6233-9
Altered cellular and humoral immunity to varicella-zoster virus in patients with autoimmune diseases.
Rondaan C, de Haan A, Horst G, Hempel JC, van Leer C, Bos NA, van Assen S, Bijl M, Westra J
Arthritis & rheumatology (Hoboken, N.J.) 2014 Nov;66(11):3122-8
Arthritis & rheumatology (Hoboken, N.J.) 2014 Nov;66(11):3122-8
Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens.
Gubin MM, Zhang X, Schuster H, Caron E, Ward JP, Noguchi T, Ivanova Y, Hundal J, Arthur CD, Krebber WJ, Mulder GE, Toebes M, Vesely MD, Lam SS, Korman AJ, Allison JP, Freeman GJ, Sharpe AH, Pearce EL, Schumacher TN, Aebersold R, Rammensee HG, Melief CJ, Mardis ER, Gillanders WE, Artyomov MN, Schreiber RD
Nature 2014 Nov 27;515(7528):577-81
Nature 2014 Nov 27;515(7528):577-81
Triple Cytokine FluoroSpot Analysis of Human Antigen-Specific IFN-γ, IL-17A and IL-22 Responses.
Dillenbeck T, Gelius E, Fohlstedt J, Ahlborg N
Cells 2014 Nov 27;3(4):1116-30
Cells 2014 Nov 27;3(4):1116-30
Microvescicles derived from mesenchymal stromal cells are not as effective as their cellular counterpart in the ability to modulate immune responses in vitro.
Conforti A, Scarsella M, Starc N, Giorda E, Biagini S, Proia A, Carsetti R, Locatelli F, Bernardo ME
Stem cells and development 2014 Nov 1;23(21):2591-9
Stem cells and development 2014 Nov 1;23(21):2591-9
P53, hTERT, WT-1, and VEGFR2 are the most suitable targets for cancer vaccine therapy in HLA-A24 positive pancreatic adenocarcinoma.
Terashima T, Mizukoshi E, Arai K, Yamashita T, Yoshida M, Ota H, Onishi I, Kayahara M, Ohtsubo K, Kagaya T, Honda M, Kaneko S
Cancer immunology, immunotherapy : CII 2014 May;63(5):479-89
Cancer immunology, immunotherapy : CII 2014 May;63(5):479-89
First-in-man clinical results with good manufacturing practice (GMP)-compliant polypeptide-expanded adenovirus-specific T cells after haploidentical hematopoietic stem cell transplantation.
Geyeregger R, Freimüller C, Stemberger J, Artwohl M, Witt V, Lion T, Fischer G, Lawitschka A, Ritter J, Hummel M, Holter W, Fritsch G, Matthes-Martin S
Journal of immunotherapy (Hagerstown, Md. : 1997) 2014 May;37(4):245-9
Journal of immunotherapy (Hagerstown, Md. : 1997) 2014 May;37(4):245-9
Results of a randomized phase I gene therapy clinical trial of nononcolytic fowlpox viruses encoding T cell costimulatory molecules.
Kaufman HL, Kim DW, Kim-Schulze S, DeRaffele G, Jagoda MC, Broucek JR, Zloza A
Human gene therapy 2014 May;25(5):452-60
Human gene therapy 2014 May;25(5):452-60
Enzyme-linked immunospot assay for detection of human respiratory syncytial virus f protein-specific gamma interferon-producing T cells.
Patton K, Aslam S, Lin J, Yu L, Lambert S, Dawes G, Esser MT, Woo J, Janetzki S, Cherukuri A
Clinical and vaccine immunology : CVI 2014 May;21(5):628-35
Clinical and vaccine immunology : CVI 2014 May;21(5):628-35
Engineering human peripheral blood stem cell grafts that are depleted of naïve T cells and retain functional pathogen-specific memory T cells.
Bleakley M, Heimfeld S, Jones LA, Turtle C, Krause D, Riddell SR, Shlomchik W
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2014 May;20(5):705-16
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2014 May;20(5):705-16
Raltegravir and elvitegravir-resistance mutation E92Q affects HLA-B*40:02-restricted HIV-1-specific CTL recognition.
Rahman MA, Kuse N, Murakoshi H, Chikata T, Gatanaga H, Oka S, Takiguchi M
Microbes and infection 2014 May;16(5):434-8
Microbes and infection 2014 May;16(5):434-8
Dominant CD4-dependent RNA-dependent RNA polymerase-specific T-cell responses in children acutely infected with human enterovirus 71 and healthy adult controls.
Dang S, Gao N, Li Y, Li M, Wang X, Jia X, Zhai S, Zhang X, Liu J, Deng H, Dong T
Immunology 2014 May;142(1):89-100
Immunology 2014 May;142(1):89-100
Switching and emergence of CTL epitopes in HIV-1 infection.
Han C, Kawana-Tachikawa A, Shimizu A, Zhu D, Nakamura H, Adachi E, Kikuchi T, Koga M, Koibuchi T, Gao GF, Sato Y, Yamagata A, Martin E, Fukai S, Brumme ZL, Iwamoto A
Retrovirology 2014 May 21;11:38
Retrovirology 2014 May 21;11:38
The human immune system recognizes neopeptides derived from mitochondrial DNA deletions.
Duvvuri B, Duvvuri VR, Wang C, Chen L, Wagar LE, Jamnik V, Wu J, Yeung RS, Grigull J, Watts TH, Wu GE
Journal of immunology (Baltimore, Md. : 1950) 2014 May 15;192(10):4581-91
Journal of immunology (Baltimore, Md. : 1950) 2014 May 15;192(10):4581-91
TCR bias and affinity define two compartments of the CD1b-glycolipid-specific T Cell repertoire.
Van Rhijn I, Gherardin NA, Kasmar A, de Jager W, Pellicci DG, Kostenko L, Tan LL, Bhati M, Gras S, Godfrey DI, Rossjohn J, Moody DB
Journal of immunology (Baltimore, Md. : 1950) 2014 May 1;192(9):4054-60
Journal of immunology (Baltimore, Md. : 1950) 2014 May 1;192(9):4054-60
Broad and potent cellular and humoral immune responses after a second late HIV-modified vaccinia virus ankara vaccination in HIV-DNA-primed and HIV-modified vaccinia virus Ankara-boosted Swedish vaccinees.
Nilsson C, Godoy-Ramirez K, Hejdeman B, Bråve A, Gudmundsdotter L, Hallengärd D, Currier JR, Wieczorek L, Hasselrot K, Earl PL, Polonis VR, Marovich MA, Robb ML, Sandström E, Wahren B, Biberfeld G
AIDS research and human retroviruses 2014 Mar;30(3):299-311
AIDS research and human retroviruses 2014 Mar;30(3):299-311
Immunological and antiviral responses after therapeutic DNA immunization in chronic hepatitis B patients efficiently treated by analogues.
Godon O, Fontaine H, Kahi S, Meritet JF, Scott-Algara D, Pol S, Michel ML, Bourgine M, ANRS HB02 study group
Molecular therapy : the journal of the American Society of Gene Therapy 2014 Mar;22(3):675-684
Molecular therapy : the journal of the American Society of Gene Therapy 2014 Mar;22(3):675-684
Enhancement of Immune Responses by Co-delivery of CCL19/MIP-3beta Chemokine Plasmid With HCV Core DNA/Protein Immunization.
Hartoonian C, Sepehrizadeh Z, Tabatabai Yazdi M, Jang YS, Langroudi L, Amir Kalvanagh P, Negahdari B, Karami A, Ebtekar M, Azadmanesh K
Hepatitis monthly 2014 Mar;14(3):e14611
Hepatitis monthly 2014 Mar;14(3):e14611
Universal cytotoxic activity of a HTLV-1 Tax-specific T cell clone from an HLA-A*24:02⁺ patient with adult T-cell leukemia against a variety of HTLV-I-infected T-cells.
Tanaka Y, Yamazaki R, Terasako-Saito K, Nakasone H, Akahoshi Y, Nakano H, Ugai T, Wada H, Yamasaki R, Ishihara Y, Kawamura K, Sakamoto K, Ashizawa M, Sato M, Kimura S, Kikuchi M, Kako S, Kanda J, Tanihara A, Nishida J, Kanda Y
Immunology letters 2014 Mar-Apr;158(1-2):120-5
Immunology letters 2014 Mar-Apr;158(1-2):120-5
Phase I clinical trial of multiple-peptide vaccination for patients with advanced biliary tract cancer.
Aruga A, Takeshita N, Kotera Y, Okuyama R, Matsushita N, Ohta T, Takeda K, Yamamoto M
Journal of translational medicine 2014 Mar 7;12:61
Journal of translational medicine 2014 Mar 7;12:61
Immunogenicity of ALVAC-HIV vCP1521 in infants of HIV-1-infected women in Uganda (HPTN 027): the first pediatric HIV vaccine trial in Africa.
Kaleebu P, Njai HF, Wang L, Jones N, Ssewanyana I, Richardson P, Kintu K, Emel L, Musoke P, Fowler MG, Ou SS, Jackson JB, Guay L, Andrew P, Baglyos L, Cao H, HPTN 027 protocol team
Journal of acquired immune deficiency syndromes (1999) 2014 Mar 1;65(3):268-77
Journal of acquired immune deficiency syndromes (1999) 2014 Mar 1;65(3):268-77
Frequent occurrence of cytomegalovirus retinitis during immune reconstitution warrants regular ophthalmic screening in high-risk pediatric allogeneic hematopoietic stem cell transplant recipients.
Hiwarkar P, Gajdosova E, Qasim W, Worth A, Breuer J, Chiesa R, Ridout D, Edelsten C, Moore A, Amrolia P, Veys P, Rao K
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2014 Jun;58(12):1700-6
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2014 Jun;58(12):1700-6
IGRA-positive patients and interferon-gamma/interleukin-2 signatures: can the Fluorospot assay provide further information?
Bittel P, Mayor D, Iseli P, Bodmer T, Suter-Riniker F
Infection 2014 Jun;42(3):539-43
Infection 2014 Jun;42(3):539-43
Clinical trial of a 7-peptide cocktail vaccine with oral chemotherapy for patients with metastatic colorectal cancer.
Okuno K, Sugiura F, Inoue K, Sukegawa Y
Anticancer research 2014 Jun;34(6):3045-52
Anticancer research 2014 Jun;34(6):3045-52
Submicroscopic infections with Plasmodium falciparum during pregnancy and their association with circulating cytokine, chemokine, and cellular profiles.
Ibitokou SA, Boström S, Brutus L, Tuikue Ndam N, Vianou B, Agbowaï C, Amadoudji Zin M, Huynh BT, Massougbodji A, Deloron P, Troye-Blomberg M, Fievet N, Luty AJ
Clinical and vaccine immunology : CVI 2014 Jun;21(6):859-66
Clinical and vaccine immunology : CVI 2014 Jun;21(6):859-66
Adjuvant effects of aluminium hydroxide-adsorbed allergens and allergoids - differences in vivo and in vitro.
Heydenreich B, Bellinghausen I, Lund L, Henmar H, Lund G, Adler Würtzen P, Saloga J
Clinical and experimental immunology 2014 Jun;176(3):310-9
Clinical and experimental immunology 2014 Jun;176(3):310-9
Viable mononuclear cell stability study for implementation in a proficiency testing program: impact of shipment conditions.
Kofanova OA, Davis K, Glazer B, De Souza Y, Kessler J, Betsou F, ISBER Biospecimen Science Working Group
Biopreservation and biobanking 2014 Jun;12(3):206-16
Biopreservation and biobanking 2014 Jun;12(3):206-16
CD8 T cell-evasive functions of human cytomegalovirus display pervasive MHC allele specificity, complementarity, and cooperativity.
Ameres S, Besold K, Plachter B, Moosmann A
Journal of immunology (Baltimore, Md. : 1950) 2014 Jun 15;192(12):5894-905
Journal of immunology (Baltimore, Md. : 1950) 2014 Jun 15;192(12):5894-905
Induction of Gag-specific CD4 T cell responses during acute HIV infection is associated with improved viral control.
Schieffer M, Jessen HK, Oster AF, Pissani F, Soghoian DZ, Lu R, Jessen AB, Zedlack C, Schultz BT, Davis I, Ranasinghe S, Rosenberg ES, Alter G, Schumann RR, Streeck H
Journal of virology 2014 Jul;88(13):7357-66
Journal of virology 2014 Jul;88(13):7357-66
Statistical methods for the assessment of EQAPOL proficiency testing: ELISpot, Luminex, and Flow Cytometry.
Rountree W, Vandergrift N, Bainbridge J, Sanchez AM, Denny TN
Journal of immunological methods 2014 Jul;409:72-81
Journal of immunological methods 2014 Jul;409:72-81
The External Quality Assurance Oversight Laboratory (EQAPOL) proficiency program for IFN-gamma enzyme-linked immunospot (IFN-γ ELISpot) assay.
Sanchez AM, Rountree W, Berrong M, Garcia A, Schuetz A, Cox J, Frahm N, Manak M, Sarzotti-Kelsoe M, D'Souza MP, Denny T, Ferrari G
Journal of immunological methods 2014 Jul;409:31-43
Journal of immunological methods 2014 Jul;409:31-43
Establishment and maintenance of a PBMC repository for functional cellular studies in support of clinical vaccine trials.
Sambor A, Garcia A, Berrong M, Pickeral J, Brown S, Rountree W, Sanchez A, Pollara J, Frahm N, Keinonen S, Kijak GH, Roederer M, Levine G, D'Souza MP, Jaimes M, Koup R, Denny T, Cox J, Ferrari G
Journal of immunological methods 2014 Jul;409:107-16
Journal of immunological methods 2014 Jul;409:107-16
Identification of host and viral factors involved in a dissimilar resolution of a hepatitis C virus infection.
Cubero M, Gregori J, Esteban JI, García-Cehic D, Bes M, Perales C, Domingo E, Rodríguez-Frías F, Sauleda S, Casillas R, Sanchez A, Ortega I, Esteban R, Guardia J, Quer J
Liver international : official journal of the International Association for the Study of the Liver 2014 Jul;34(6):896-906
Liver international : official journal of the International Association for the Study of the Liver 2014 Jul;34(6):896-906
Differential T-cell responses of semi-immune and susceptible malaria subjects to in silico predicted and synthetic peptides of Plasmodium falciparum.
Dinga JN, Kimbung Mbandi S, Cho-Ngwa F, Fon NP, Moliki J, Efeti RM, Nyasa BR, Anong DN, Jojic N, Heckerman D, Wang R, Titanji VP
Acta tropica 2014 Jul;135:104-21
Acta tropica 2014 Jul;135:104-21
Immunotherapy with an HIV-DNA Vaccine in Children and Adults.
Palma P, Gudmundsdotter L, Finocchi A, Eriksson LE, Mora N, Santilli V, Aquilani A, Manno EC, Zangari P, Romiti ML, Montesano C, Grifoni A, Brave A, Ljungberg K, Blomberg P, Bernardi S, Sandström E, Hejdeman B, Rossi P, Wahren B
Vaccines 2014 Jul 17;2(3):563-80
Vaccines 2014 Jul 17;2(3):563-80
Efficient identification of mutated cancer antigens recognized by T cells associated with durable tumor regressions.
Lu YC, Yao X, Crystal JS, Li YF, El-Gamil M, Gross C, Davis L, Dudley ME, Yang JC, Samuels Y, Rosenberg SA, Robbins PF
Clinical cancer research : an official journal of the American Association for Cancer Research 2014 Jul 1;20(13):3401-10
Clinical cancer research : an official journal of the American Association for Cancer Research 2014 Jul 1;20(13):3401-10
T cell response to alpha crystallin and Mycobacterium tuberculosis specific antigens using ex-vivo elispot assay for detecting latent tuberculosis infection in Addis Ababa, Ethiopia.
Mamo G, Mihret A, Taffesse M, Gebru G, Afework M, Yamuah LK, Wassie L, Abebe M, Aseffa A, Parida SK
Ethiopian medical journal 2014 Jan;Suppl 1:15-22
Ethiopian medical journal 2014 Jan;Suppl 1:15-22
Immunoprevalence and immunodominance of HLA-Cw*0801-restricted T cell response targeting the hepatitis B virus envelope transmembrane region.
Tan AT, Sodsai P, Chia A, Moreau E, Chng MH, Tham CY, Ho ZZ, Banu N, Hirankarn N, Bertoletti A
Journal of virology 2014 Jan;88(2):1332-41
Journal of virology 2014 Jan;88(2):1332-41
Brucella melitensis T cell epitope recognition in humans with brucellosis in Peru.
Cannella AP, Arlehamn CS, Sidney J, Patra KP, Torres K, Tsolis RM, Liang L, Felgner PL, Saito M, Gotuzzo E, Gilman RH, Sette A, Vinetz JM
Infection and immunity 2014 Jan;82(1):124-31
Infection and immunity 2014 Jan;82(1):124-31
A phase I clinical trial of vaccination with KIF20A-derived peptide in combination with gemcitabine for patients with advanced pancreatic cancer.
Suzuki N, Hazama S, Ueno T, Matsui H, Shindo Y, Iida M, Yoshimura K, Yoshino S, Takeda K, Oka M
Journal of immunotherapy (Hagerstown, Md. : 1997) 2014 Jan;37(1):36-42
Journal of immunotherapy (Hagerstown, Md. : 1997) 2014 Jan;37(1):36-42
Combination of Epstein-Barr virus nuclear antigen 1, 3 and lytic antigen BZLF1 peptide pools allows fast and efficient stimulation of Epstein-Barr virus-specific T cells for adoptive immunotherapy.
Wang Y, Aïssi-Rothe L, Virion JM, De Carvalho Bittencourt M, Ulas N, Audonnet S, Salmon A, Clement L, Venard V, Jeulin H, Stoltz JF, Decot V, Bensoussan D
Cytotherapy 2014 Jan;16(1):122-34
Cytotherapy 2014 Jan;16(1):122-34
Detection of HCV-Specific IFN-γ Responses in HCV Antibody and HCV RNA Negative Injecting Drug Users.
Flynn JK, Sacks-Davis R, Higgs P, Aitken C, Moneer S, Suppiah V, Tracy L, Ffrench R, Bowden S, Drummer H, George J, Bharadwaj M, Hellard M
Hepatitis monthly 2014 Jan;14(1):e14678
Hepatitis monthly 2014 Jan;14(1):e14678
Anti-melanoma activity of T cells redirected with a TCR-like chimeric antigen receptor.
Zhang G, Wang L, Cui H, Wang X, Zhang G, Ma J, Han H, He W, Wang W, Zhao Y, Liu C, Sun M, Gao B
Scientific reports 2014 Jan 6;4:3571
Scientific reports 2014 Jan 6;4:3571
Systemic treatment with CAR-engineered T cells against PSCA delays subcutaneous tumor growth and prolongs survival of mice.
Hillerdal V, Ramachandran M, Leja J, Essand M
BMC cancer 2014 Jan 18;14:30
BMC cancer 2014 Jan 18;14:30
Memory CD8(+) T cells elicited by HIV-1 lipopeptide vaccines display similar phenotypic profiles but differences in term of magnitude and multifunctionality compared with FLU- or EBV-specific memory T cells in humans.
Figueiredo S, Charmeteau B, Surenaud M, Salmon D, Launay O, Guillet JG, Hosmalin A, Gahery H
Vaccine 2014 Jan 16;32(4):492-501
Vaccine 2014 Jan 16;32(4):492-501
Susceptibility to CD8 T-cell-mediated killing influences the reservoir of latently HIV-1-infected CD4 T cells.
Buzon MJ, Yang Y, Ouyang Z, Sun H, Seiss K, Rogich J, Le Gall S, Pereyra F, Rosenberg ES, Yu XG, Lichterfeld M
Journal of acquired immune deficiency syndromes (1999) 2014 Jan 1;65(1):1-9
Journal of acquired immune deficiency syndromes (1999) 2014 Jan 1;65(1):1-9
Long-lasting disease stabilization in the absence of toxicity in metastatic lung cancer patients vaccinated with an epitope derived from indoleamine 2,3 dioxygenase.
Iversen TZ, Engell-Noerregaard L, Ellebaek E, Andersen R, Larsen SK, Bjoern J, Zeyher C, Gouttefangeas C, Thomsen BM, Holm B, Thor Straten P, Mellemgaard A, Andersen MH, Svane IM
Clinical cancer research : an official journal of the American Association for Cancer Research 2014 Jan 1;20(1):221-32
Clinical cancer research : an official journal of the American Association for Cancer Research 2014 Jan 1;20(1):221-32
Human cytotoxic T lymphocytes directed to seasonal influenza A viruses cross-react with the newly emerging H7N9 virus.
van de Sandt CE, Kreijtz JH, de Mutsert G, Geelhoed-Mieras MM, Hillaire ML, Vogelzang-van Trierum SE, Osterhaus AD, Fouchier RA, Rimmelzwaan GF
Journal of virology 2014 Feb;88(3):1684-93
Journal of virology 2014 Feb;88(3):1684-93
Interferon-gamma ELISPOT detecting reactivity of T cells to TSH receptor peptides in Graves' disease.
Côté-Bigras S, Dionne A, Asselin-Mullen P, Leblicq C, Rottembourg D
Clinical endocrinology 2014 Feb;80(2):296-300
Clinical endocrinology 2014 Feb;80(2):296-300
Pre-eclampsia affects cord blood NK cell expression of activation receptors and serum cytokine levels but not CB monocyte characteristics.
Sohlberg E, Saghafian-Hedengren S, Bachmayer N, Hamad RR, Bremme K, Holmlund U
American journal of reproductive immunology (New York, N.Y. : 1989) 2014 Feb;71(2):178-88
American journal of reproductive immunology (New York, N.Y. : 1989) 2014 Feb;71(2):178-88
Adoptive immunotherapy with antigen-specific T cells during extracorporeal membrane oxygenation (ECMO) for adenovirus-related respiratory failure in a child given haploidentical stem cell transplantation.
Di Nardo M, Li Pira G, Amodeo A, Cecchetti C, Giorda E, Ceccarelli S, Brescia LP, Pirozzi N, Rutella S, Locatelli F, Bertaina A
Pediatric blood & cancer 2014 Feb;61(2):376-9
Pediatric blood & cancer 2014 Feb;61(2):376-9
Vaccine-elicited human T cells recognizing conserved protein regions inhibit HIV-1.
Borthwick N, Ahmed T, Ondondo B, Hayes P, Rose A, Ebrahimsa U, Hayton EJ, Black A, Bridgeman A, Rosario M, Hill AV, Berrie E, Moyle S, Frahm N, Cox J, Colloca S, Nicosia A, Gilmour J, McMichael AJ, Dorrell L, Hanke T
Molecular therapy : the journal of the American Society of Gene Therapy 2014 Feb;22(2):464-475
Molecular therapy : the journal of the American Society of Gene Therapy 2014 Feb;22(2):464-475
Ex-vivo whole blood secretion of interferon (IFN)-γ and IFN-γ-inducible protein-10 measured by enzyme-linked immunosorbent assay are as sensitive as IFN-γ enzyme-linked immunospot for the detection of gluten-reactive T cells in human leucocyte antigen (HLA)-DQ2·5(+) -associated coeliac disease.
Ontiveros N, Tye-Din JA, Hardy MY, Anderson RP
Clinical and experimental immunology 2014 Feb;175(2):305-15
Clinical and experimental immunology 2014 Feb;175(2):305-15
The immunological and clinical effects of mutated ras peptide vaccine in combination with IL-2, GM-CSF, or both in patients with solid tumors.
Rahma OE, Hamilton JM, Wojtowicz M, Dakheel O, Bernstein S, Liewehr DJ, Steinberg SM, Khleif SN
Journal of translational medicine 2014 Feb 24;12:55
Journal of translational medicine 2014 Feb 24;12:55
CD8+ T cells are activated in an antigen-independent manner in HIV-infected individuals.
Bastidas S, Graw F, Smith MZ, Kuster H, Günthard HF, Oxenius A
Journal of immunology (Baltimore, Md. : 1950) 2014 Feb 15;192(4):1732-44
Journal of immunology (Baltimore, Md. : 1950) 2014 Feb 15;192(4):1732-44
Gap junction intercellular communications regulate NK cell activation and modulate NK cytotoxic capacity.
Tittarelli A, Mendoza-Naranjo A, Farías M, Guerrero I, Ihara F, Wennerberg E, Riquelme S, Gleisner A, Kalergis A, Lundqvist A, López MN, Chambers BJ, Salazar-Onfray F
Journal of immunology (Baltimore, Md. : 1950) 2014 Feb 1;192(3):1313-9
Journal of immunology (Baltimore, Md. : 1950) 2014 Feb 1;192(3):1313-9
High IP-10 levels decrease T cell function in HIV-1-infected individuals on ART.
Ramirez LA, Arango TA, Thompson E, Naji M, Tebas P, Boyer JD
Journal of leukocyte biology 2014 Dec;96(6):1055-63
Journal of leukocyte biology 2014 Dec;96(6):1055-63
A registry of HLA-typed donors for production of virus-specific CD4 and CD8 T lymphocytes for adoptive reconstitution of immune-compromised patients.
Li Pira G, Ivaldi F, Starc N, Landi F, Rutella S, Locatelli F, Sacchi N, Tripodi G, Manca F
Transfusion 2014 Dec;54(12):3145-54
Transfusion 2014 Dec;54(12):3145-54
Seasonal influenza vaccination is the strongest correlate of cross-reactive antibody responses in migratory bird handlers.
Oshansky CM, Wong SS, Jeevan T, Smallwood HS, Webby RJ, Shafir SC, Thomas PG
mBio 2014 Dec 9;5(6):e02107
mBio 2014 Dec 9;5(6):e02107
Pre-immature dendritic cells (PIDC) pulsed with HPV16 E6 or E7 peptide are capable of eliciting specific immune response in patients with advanced cervical cancer.
Rahma OE, Herrin VE, Ibrahim RA, Toubaji A, Bernstein S, Dakheel O, Steinberg SM, Abu Eid R, Mkrtichyan M, Berzofsky JA, Khleif SN
Journal of translational medicine 2014 Dec 16;12:353
Journal of translational medicine 2014 Dec 16;12:353
Chemoradiotherapy-induced upregulation of PD-1 antagonizes immunity to HPV-related oropharyngeal cancer.
Parikh F, Duluc D, Imai N, Clark A, Misiukiewicz K, Bonomi M, Gupta V, Patsias A, Parides M, Demicco EG, Zhang DY, Kim-Schulze S, Kao J, Gnjatic S, Oh S, Posner MR, Sikora AG
Cancer research 2014 Dec 15;74(24):7205-16
Cancer research 2014 Dec 15;74(24):7205-16
Experimental evidence that mutated-self peptides derived from mitochondrial DNA somatic mutations have the potential to trigger autoimmunity.
Chen L, Duvvuri B, Grigull J, Jamnik R, Wither JE, Wu GE
Human immunology 2014 Aug;75(8):873-9
Human immunology 2014 Aug;75(8):873-9
Mesenchymal stromal cell therapy is associated with increased adenovirus-associated but not cytomegalovirus-associated mortality in children with severe acute graft-versus-host disease.
Calkoen FG, Vervat C, van Halteren AG, Welters MJ, Veltrop-Duits LA, Lankester AC, Egeler RM, Ball LM, van Tol MJ
Stem cells translational medicine 2014 Aug;3(8):899-910
Stem cells translational medicine 2014 Aug;3(8):899-910
Artificial antigen-presenting cells expressing CD80, CD70, and 4-1BB ligand efficiently expand functional T cells specific to tumor-associated antigens.
Zeng W, Su M, Anderson KS, Sasada T
Immunobiology 2014 Aug;219(8):583-92
Immunobiology 2014 Aug;219(8):583-92
IFN-gamma and TNF associated with severe falciparum malaria infection in Saudi pregnant women.
Nasr A, Allam G, Hamid O, Al-Ghamdi A
Malaria journal 2014 Aug 13;13:314
Malaria journal 2014 Aug 13;13:314
Alpha fetoprotein DNA prime and adenovirus boost immunization of two hepatocellular cancer patients.
Butterfield LH, Economou JS, Gamblin TC, Geller DA
Journal of translational medicine 2014 Apr 5;12:86
Journal of translational medicine 2014 Apr 5;12:86
Phase I clinical study of multiple epitope peptide vaccine combined with chemoradiation therapy in esophageal cancer patients.
Iinuma H, Fukushima R, Inaba T, Tamura J, Inoue T, Ogawa E, Horikawa M, Ikeda Y, Matsutani N, Takeda K, Yoshida K, Tsunoda T, Ikeda T, Nakamura Y, Okinaga K
Journal of translational medicine 2014 Apr 3;12:84
Journal of translational medicine 2014 Apr 3;12:84
Impact of immunosuppression on recall immune responses to influenza vaccination in stable renal transplant recipients.
Cowan M, Chon WJ, Desai A, Andrews S, Bai Y, Veguilla V, Katz JM, Josephson MA, Wilson PC, Sciammas R, Chong AS
Transplantation 2014 Apr 27;97(8):846-53
Transplantation 2014 Apr 27;97(8):846-53
Specific active immunotherapy with a VEGF vaccine in patients with advanced solid tumors. results of the CENTAURO antigen dose escalation phase I clinical trial.
Gavilondo JV, Hernández-Bernal F, Ayala-Ávila M, de la Torre AV, de la Torre J, Morera-Díaz Y, Bequet-Romero M, Sánchez J, Valenzuela CM, Martín Y, Selman-Housein KH, Garabito A, Lazo OC, CENTAURO Group of Investigators
Vaccine 2014 Apr 17;32(19):2241-50
Vaccine 2014 Apr 17;32(19):2241-50
Highly significant antiviral activity of HIV-1 LTR-specific tre-recombinase in humanized mice.
Hauber I, Hofmann-Sieber H, Chemnitz J, Dubrau D, Chusainow J, Stucka R, Hartjen P, Schambach A, Ziegler P, Hackmann K, Schröck E, Schumacher U, Lindner C, Grundhoff A, Baum C, Manz MG, Buchholz F, Hauber J
PLoS pathogens 2013;9(9):e1003587
PLoS pathogens 2013;9(9):e1003587
Presentation of an immunodominant immediate-early CD8+ T cell epitope resists human cytomegalovirus immunoevasion.
Ameres S, Mautner J, Schlott F, Neuenhahn M, Busch DH, Plachter B, Moosmann A
PLoS pathogens 2013;9(5):e1003383
PLoS pathogens 2013;9(5):e1003383
Impairment of IFN-gamma response to synthetic peptides of Mycobacterium tuberculosis in a 7-day whole blood assay.
Gideon HP, Hamilton MS, Wood K, Pepper D, Oni T, Seldon R, Banwell C, Langford PR, Wilkinson RJ, Wilkinson KA
PloS one 2013;8(8):e71351
PloS one 2013;8(8):e71351
Trivalent combination vaccine induces broad heterologous immune responses to norovirus and rotavirus in mice.
Tamminen K, Lappalainen S, Huhti L, Vesikari T, Blazevic V
PloS one 2013;8(7):e70409
PloS one 2013;8(7):e70409
Bee Venom Phospholipase A2, a Good "Chauffeur" for Delivering Tumor Antigen to the MHC I and MHC II Peptide-Loading Compartments of the Dendritic Cells: The Case of NY-ESO-1.
Almunia C, Bretaudeau M, Held G, Babon A, Marchetti C, Castelli FA, Ménez A, Maillere B, Gillet D
PloS one 2013;8(6):e67645
PloS one 2013;8(6):e67645
Two doses of candidate TB vaccine MVA85A in antiretroviral therapy (ART) naïve subjects gives comparable immunogenicity to one dose in ART+ subjects.
Dieye TN, Ndiaye BP, Dieng AB, Fall M, Brittain N, Vermaak S, Camara M, Diop-Ndiaye H, Ngom-Gueye NF, Diaw PA, Toure-Kane C, Sow PS, Mboup S, McShane H
PloS one 2013;8(6):e67177
PloS one 2013;8(6):e67177
Virus-specific immune response in HBeAg-negative chronic hepatitis B: relationship with clinical profile and HBsAg serum levels.
Loggi E, Bihl FK, Cursaro C, Granieri C, Galli S, Brodosi L, Furlini G, Bernardi M, Brander C, Andreone P
PloS one 2013;8(6):e65327
PloS one 2013;8(6):e65327
Cytotoxicity of tumor antigen specific human T cells is unimpaired by arginine depletion.
Munder M, Engelhardt M, Knies D, Medenhoff S, Wabnitz G, Luckner-Minden C, Feldmeyer N, Voss RH, Kropf P, Müller I, Conradi R, Samstag Y, Theobald M, Ho AD, Goldschmidt H, Hundemer M
PloS one 2013;8(5):e63521
PloS one 2013;8(5):e63521
Short-term in-vitro expansion improves monitoring and allows affordable generation of virus-specific T-cells against several viruses for a broad clinical application.
Geyeregger R, Freimüller C, Stevanovic S, Stemberger J, Mester G, Dmytrus J, Lion T, Rammensee HG, Fischer G, Eiz-Vesper B, Lawitschka A, Matthes S, Fritsch G
PloS one 2013;8(4):e59592
PloS one 2013;8(4):e59592
Use of RT-defective HIV virions: new tool to evaluate specific response in chronic asymptomatic HIV-infected individuals.
Guardo AC, Alvarez-Fernández C, Arberas H, García-Pérez J, García F, Bargalló ME, Maleno MJ, Gatell JM, Mothe B, Alcami J, Sánchez-Palomino S, Plana M
PloS one 2013;8(3):e58927
PloS one 2013;8(3):e58927
IRX-2, a novel immunotherapeutic, enhances functions of human dendritic cells.
Schilling B, Harasymczuk M, Schuler P, Egan J, Ferrone S, Whiteside TL
PloS one 2013;8(2):e47234
PloS one 2013;8(2):e47234
Challenges in the development of an immunochromatographic interferon-gamma test for diagnosis of pleural tuberculosis.
Denkinger CM, Kalantri Y, Schumacher SG, Michael JS, Shankar D, Saxena A, Sriram N, Balamugesh T, Luo R, Pollock NR, Pai M, Christopher DJ
PloS one 2013;8(12):e85447
PloS one 2013;8(12):e85447
Loss of multi-epitope specificity in memory CD4(+) T cell responses to B. pertussis with age.
Han WG, van Twillert I, Poelen MC, Helm K, van de Kassteele J, Verheij TJ, Versteegh FG, Boog CJ, van Els CA
PloS one 2013;8(12):e83583
PloS one 2013;8(12):e83583
Recall responses to tetanus and diphtheria vaccination are frequently insufficient in elderly persons.
Weinberger B, Schirmer M, Matteucci Gothe R, Siebert U, Fuchs D, Grubeck-Loebenstein B
PloS one 2013;8(12):e82967
PloS one 2013;8(12):e82967
A phase 1b randomized, controlled, double-blinded dosage-escalation trial to evaluate the safety, reactogenicity and immunogenicity of an adenovirus type 35 based circumsporozoite malaria vaccine in Burkinabe healthy adults 18 to 45 years of age.
Ouédraogo A, Tiono AB, Kargougou D, Yaro JB, Ouédraogo E, Kaboré Y, Kangoye D, Bougouma EC, Gansane A, Henri N, Diarra A, Sanon S, Soulama I, Konate AT, Watson NL, Brown V, Hendriks J, Pau MG, Versteege I, Wiesken E, Sadoff J, Nebie I, Sirima SB
PloS one 2013;8(11):e78679
PloS one 2013;8(11):e78679
Preserved antigen-specific immune response in patients with multiple sclerosis responding to IFNβ-therapy.
Mehling M, Fritz S, Hafner P, Eichin D, Yonekawa T, Klimkait T, Lindberg RL, Kappos L, Hess C
PloS one 2013;8(11):e78532
PloS one 2013;8(11):e78532
Biological, functional and genetic characterization of bone marrow-derived mesenchymal stromal cells from pediatric patients affected by acute lymphoblastic leukemia.
Conforti A, Biagini S, Del Bufalo F, Sirleto P, Angioni A, Starc N, Li Pira G, Moretta F, Proia A, Contoli B, Genovese S, Ciardi C, Avanzini MA, Rosti V, Lo-Coco F, Locatelli F, Bernardo ME
PloS one 2013;8(11):e76989
PloS one 2013;8(11):e76989
Lactobacilli regulate Staphylococcus aureus 161:2-induced pro-inflammatory T-cell responses in vitro.
Haileselassie Y, Johansson MA, Zimmer CL, Björkander S, Petursdottir DH, Dicksved J, Petersson M, Persson JO, Fernandez C, Roos S, Holmlund U, Sverremark-Ekström E
PloS one 2013;8(10):e77893
PloS one 2013;8(10):e77893
Suppression of virus specific immune responses by IL-10 in acute dengue infection.
Malavige GN, Jeewandara C, Alles KM, Salimi M, Gomes L, Kamaladasa A, Jayaratne SD, Ogg GS
PLoS neglected tropical diseases 2013;7(9):e2409
PLoS neglected tropical diseases 2013;7(9):e2409
Expansion in CD39⁺ CD4⁺ immunoregulatory t cells and rarity of Th17 cells in HTLV-1 infected patients is associated with neurological complications.
Leal FE, Ndhlovu LC, Hasenkrug AM, Bruno FR, Carvalho KI, Wynn-Williams H, Neto WK, Sanabani SS, Segurado AC, Nixon DF, Kallas EG
PLoS neglected tropical diseases 2013;7(2):e2028
PLoS neglected tropical diseases 2013;7(2):e2028
An Influenza Virus M2 Protein Specific Chimeric Antigen Receptor Modulates Influenza A/WSN/33 H1N1 Infection In Vivo.
Talbot SJ, Blair NF, McGill N, Ligertwood Y, Dutia BM, Johannessen I
The open virology journal 2013;7:28-36
The open virology journal 2013;7:28-36
Protective CD8+ T-cell immunity to human malaria induced by chimpanzee adenovirus-MVA immunisation.
Ewer KJ, O'Hara GA, Duncan CJ, Collins KA, Sheehy SH, Reyes-Sandoval A, Goodman AL, Edwards NJ, Elias SC, Halstead FD, Longley RJ, Rowland R, Poulton ID, Draper SJ, Blagborough AM, Berrie E, Moyle S, Williams N, Siani L, Folgori A, Colloca S, Sinden RE, Lawrie AM, Cortese R, Gilbert SC, Nicosia A, Hill AV
Nature communications 2013;4:2836
Nature communications 2013;4:2836
Brief Exercise Increases Peripheral Blood NK Cell Counts without Immediate Functional Changes, but Impairs their Responses to ex vivo Stimulation.
Millard AL, Valli PV, Stussi G, Mueller NJ, Yung GP, Seebach JD
Frontiers in immunology 2013;4:125
Frontiers in immunology 2013;4:125
Placenta-derived gp96 as a multivalent prophylactic cancer vaccine.
Zhao B, Wang Y, Wu B, Liu S, Wu E, Fan H, Gui M, Chen L, Li C, Ju Y, Zhang W, Meng S
Scientific reports 2013;3:1947
Scientific reports 2013;3:1947
T-Cell Response to Hepatitis B Core Antigen: Identification of Prior Exposure to and Confirmatory Testing for Screening for Anti-HBc.
Araujo P, Dodd RY, Latinni F, Souza R, Diaz R, Barreto JA
Journal of biomarkers 2013;2013:812170
Journal of biomarkers 2013;2013:812170
Comparing effects of BK virus agnoprotein and herpes simplex-1 ICP47 on MHC-I and MHC-II expression.
Cioni M, Mittelholzer C, Wernli M, Hirsch HH
Clinical & developmental immunology 2013;2013:626823
Clinical & developmental immunology 2013;2013:626823
Application of IgG-derived natural Treg epitopes (IgG Tregitopes) to antigen-specific tolerance induction in a murine model of type 1 diabetes.
Cousens LP, Su Y, McClaine E, Li X, Terry F, Smith R, Lee J, Martin W, Scott DW, De Groot AS
Journal of diabetes research 2013;2013:621693
Journal of diabetes research 2013;2013:621693
Therapeutic DNA vaccination using in vivo electroporation followed by standard of care therapy in patients with genotype 1 chronic hepatitis C.
Weiland O, Ahlén G, Diepolder H, Jung MC, Levander S, Fons M, Mathiesen I, Sardesai NY, Vahlne A, Frelin L, Sällberg M
Molecular therapy : the journal of the American Society of Gene Therapy 2013 Sep;21(9):1796-805
Molecular therapy : the journal of the American Society of Gene Therapy 2013 Sep;21(9):1796-805
T-cell immunophenotyping distinguishes active from latent tuberculosis.
Pollock KM, Whitworth HS, Montamat-Sicotte DJ, Grass L, Cooke GS, Kapembwa MS, Kon OM, Sampson RD, Taylor GP, Lalvani A
The Journal of infectious diseases 2013 Sep;208(6):952-68
The Journal of infectious diseases 2013 Sep;208(6):952-68
Enzyme-linked immunospot assay response to recombinant CFP-10/ESAT-6 fusion protein among patients with spinal tuberculosis: implications for diagnosis and monitoring of surgical therapy.
Yuan K, Wu X, Zhang Q, Zhong Z, Chen J
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 2013 Sep;17(9):e733-8
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 2013 Sep;17(9):e733-8
Autologous CLL cell vaccination early after transplant induces leukemia-specific T cells.
Burkhardt UE, Hainz U, Stevenson K, Goldstein NR, Pasek M, Naito M, Wu D, Ho VT, Alonso A, Hammond NN, Wong J, Sievers QL, Brusic A, McDonough SM, Zeng W, Perrin A, Brown JR, Canning CM, Koreth J, Cutler C, Armand P, Neuberg D, Lee JS, Antin JH, Mulligan RC, Sasada T, Ritz J, Soiffer RJ, Dranoff G, Alyea EP, Wu CJ
The Journal of clinical investigation 2013 Sep;123(9):3756-65
The Journal of clinical investigation 2013 Sep;123(9):3756-65
Lower CD28+ T cell proportions were associated with CMV-seropositivity in patients with Hashimoto's thyroiditis.
Prelog M, Schönlaub J, Würzner R, Koppelstaetter C, Almanzar G, Brunner A, Gasser M, Prommegger R, Häusler G, Kapelari K, Högler W
BMC endocrine disorders 2013 Sep 5;13:34
BMC endocrine disorders 2013 Sep 5;13:34
Lack of variant specific CD8+ T-cell response against mutant and pre-existing variants leads to outgrowth of particular clones in acute hepatitis C.
Ulsenheimer A, Paranhos-Baccalà G, Komurian-Pradel F, Raziorrouh B, Kurktschiev P, Diepolder HM, Zachoval R, Spannagl M, Jung MC, Gruener NH
Virology journal 2013 Sep 28;10:295
Virology journal 2013 Sep 28;10:295
Generation of tumor antigen-specific T cell lines from pediatric patients with acute lymphoblastic leukemia--implications for immunotherapy.
Weber G, Caruana I, Rouce RH, Barrett AJ, Gerdemann U, Leen AM, Rabin KR, Bollard CM
Clinical cancer research : an official journal of the American Association for Cancer Research 2013 Sep 15;19(18):5079-91
Clinical cancer research : an official journal of the American Association for Cancer Research 2013 Sep 15;19(18):5079-91
Long-term CD4(+) and CD8(+) T-cell responses induced in HIV-uninfected volunteers following intradermal or intramuscular administration of an HIV-lipopeptide vaccine (ANRS VAC16).
Launay O, Surenaud M, Desaint C, Ben Hamouda N, Pialoux G, Bonnet B, Poizot-Martin I, Gonzales G, Cuzin L, Bourgault-Villada I, Lévy Y, Choppin J, Durier C
Vaccine 2013 Sep 13;31(40):4406-15
Vaccine 2013 Sep 13;31(40):4406-15
The effect of rituximab on vaccine responses in patients with immune thrombocytopenia.
Nazi I, Kelton JG, Larché M, Snider DP, Heddle NM, Crowther MA, Cook RJ, Tinmouth AT, Mangel J, Arnold DM
Blood 2013 Sep 12;122(11):1946-53
Blood 2013 Sep 12;122(11):1946-53
Characterization of the T-cell-mediated immune response against the Aspergillus fumigatus proteins Crf1 and catalase 1 in healthy individuals.
Jolink H, Meijssen IC, Hagedoorn RS, Arentshorst M, Drijfhout JW, Mulder A, Claas FH, van Dissel JT, Falkenburg JH, Heemskerk MH
The Journal of infectious diseases 2013 Sep 1;208(5):847-56
The Journal of infectious diseases 2013 Sep 1;208(5):847-56
Temperature fluctuations during deep temperature cryopreservation reduce PBMC recovery, viability and T-cell function.
Germann A, Oh YJ, Schmidt T, Schön U, Zimmermann H, von Briesen H
Cryobiology 2013 Oct;67(2):193-200
Cryobiology 2013 Oct;67(2):193-200
Evaluation of human cytomegalovirus-specific CD8+ T-cells in allogeneic haematopoietic stem cell transplant recipients using pentamer and interferon-γ-enzyme-linked immunospot assays.
Liu A, Ma Y, Wu W, Chen X, Huang Y, Hu J, Liang H, Wang H, Yang R, Fan J
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2013 Oct;58(2):427-31
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2013 Oct;58(2):427-31
Quantification of IFNγ- and IL17-producing cells after stimulation with citrullinated proteins in healthy subjects and RA patients.
Van Steendam K, De Ceuleneer M, Tilleman K, Elewaut D, De Keyser F, Deforce D
Rheumatology international 2013 Oct;33(10):2661-4
Rheumatology international 2013 Oct;33(10):2661-4
Decreased functional T lymphocyte-mediated cytokine responses in patients with chemotherapy-induced neutropenia.
Öhrmalm L, Smedman C, Wong M, Broliden K, Tolfvenstam T, Norbeck O
Journal of internal medicine 2013 Oct;274(4):363-70
Journal of internal medicine 2013 Oct;274(4):363-70
Modification of hematopoietic stem/progenitor cells with CD19-specific chimeric antigen receptors as a novel approach for cancer immunotherapy.
De Oliveira SN, Ryan C, Giannoni F, Hardee CL, Tremcinska I, Katebian B, Wherley J, Sahaghian A, Tu A, Grogan T, Elashoff D, Cooper LJ, Hollis RP, Kohn DB
Human gene therapy 2013 Oct;24(10):824-39
Human gene therapy 2013 Oct;24(10):824-39
Response to HER-2 pulsed DC1 vaccines is predicted by both HER-2 and estrogen receptor expression in DCIS.
Fracol M, Xu S, Mick R, Fitzpatrick E, Nisenbaum H, Roses R, Fisher C, Tchou J, Fox K, Zhang P, Czerniecki BJ
Annals of surgical oncology 2013 Oct;20(10):3233-9
Annals of surgical oncology 2013 Oct;20(10):3233-9
CMV-, EBV- and ADV-specific T cell immunity: screening and monitoring of potential third-party donors to improve post-transplantation outcome.
Sukdolak C, Tischer S, Dieks D, Figueiredo C, Goudeva L, Heuft HG, Verboom M, Immenschuh S, Heim A, Borchers S, Mischak-Weissinger E, Blasczyk R, Maecker-Kolhoff B, Eiz-Vesper B
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2013 Oct;19(10):1480-92
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2013 Oct;19(10):1480-92
Cellular immune correlates of protection against symptomatic pandemic influenza.
Sridhar S, Begom S, Bermingham A, Hoschler K, Adamson W, Carman W, Bean T, Barclay W, Deeks JJ, Lalvani A
Nature medicine 2013 Oct;19(10):1305-12
Nature medicine 2013 Oct;19(10):1305-12
Enhancement of tumor-reactive cytotoxic CD4+ T cell responses after ipilimumab treatment in four advanced melanoma patients.
Kitano S, Tsuji T, Liu C, Hirschhorn-Cymerman D, Kyi C, Mu Z, Allison JP, Gnjatic S, Yuan JD, Wolchok JD
Cancer immunology research 2013 Oct;1(4):235-44
Cancer immunology research 2013 Oct;1(4):235-44
Merkel polyomavirus-specific T cells fluctuate with merkel cell carcinoma burden and express therapeutically targetable PD-1 and Tim-3 exhaustion markers.
Afanasiev OK, Yelistratova L, Miller N, Nagase K, Paulson K, Iyer JG, Ibrani D, Koelle DM, Nghiem P
Clinical cancer research : an official journal of the American Association for Cancer Research 2013 Oct 1;19(19):5351-60
Clinical cancer research : an official journal of the American Association for Cancer Research 2013 Oct 1;19(19):5351-60
A case of sulfasalazine-induced hypersensitivity syndrome confirmed by enzyme-linked immunospot assay.
Phatharacharukul P, Klaewsongkram J
Allergy, asthma & immunology research 2013 Nov;5(6):415-7
Allergy, asthma & immunology research 2013 Nov;5(6):415-7
Maintenance of Th1 hepatitis C virus (HCV)-specific responses in individuals with acute HCV who achieve sustained virological clearance after treatment.
Flynn JK, Dore GJ, Hellard M, Yeung B, Rawlinson WD, White PA, Kaldor JM, Lloyd AR, Ffrench RA, ATAHC Study Group
Journal of gastroenterology and hepatology 2013 Nov;28(11):1770-81
Journal of gastroenterology and hepatology 2013 Nov;28(11):1770-81
Identification of human leucocyte antigen (HLA)-A*0201-restricted cytotoxic T lymphocyte epitopes derived from HLA-DOβ as a novel target for multiple myeloma.
Kang YJ, Zeng W, Song W, Reinhold B, Choi J, Brusic V, Yamashita T, Munshi A, Li C, Minvielle S, Anderson KC, Munshi N, Reinherz EL, Sasada T
British journal of haematology 2013 Nov;163(3):343-51
British journal of haematology 2013 Nov;163(3):343-51
Structure-based design of altered MHC class II-restricted peptide ligands with heterogeneous immunogenicity.
Chen S, Li Y, Depontieu FR, McMiller TL, English AM, Shabanowitz J, Kos F, Sidney J, Sette A, Rosenberg SA, Hunt DF, Mariuzza RA, Topalian SL
Journal of immunology (Baltimore, Md. : 1950) 2013 Nov 15;191(10):5097-106
Journal of immunology (Baltimore, Md. : 1950) 2013 Nov 15;191(10):5097-106
High proportions of regulatory B and T cells are associated with decreased cellular responses to pH1N1 influenza vaccine in HIV-infected children and youth (IMPAACT P1088).
Weinberg A, Muresan P, Fenton T, Richardson K, Dominguez T, Bloom A, Petzold E, Anthony P, Cunningham CK, Spector SA, Nachman S, Siberry GK, Handelsman E, Flynn PM, IMPAACT P1088 study team
Human vaccines & immunotherapeutics 2013 May;9(5):957-68
Human vaccines & immunotherapeutics 2013 May;9(5):957-68
Immunological hallmarks of JC virus replication in multiple sclerosis patients on long-term natalizumab therapy.
Hendel-Chavez H, de Goër de Herve MG, Giannesini C, Mazet AA, Papeix C, Louapre C, Chardain A, Boutarfa N, Théaudin M, Adams D, Gasnault J, Stankoff B, Taoufik Y
Journal of virology 2013 May;87(10):6055-9
Journal of virology 2013 May;87(10):6055-9
A strategy to determine HLA class II restriction broadly covering the DR, DP, and DQ allelic variants most commonly expressed in the general population.
McKinney DM, Southwood S, Hinz D, Oseroff C, Arlehamn CS, Schulten V, Taplitz R, Broide D, Hanekom WA, Scriba TJ, Wood R, Alam R, Peters B, Sidney J, Sette A
Immunogenetics 2013 May;65(5):357-70
Immunogenetics 2013 May;65(5):357-70
Effects of cyclophosphamide and IL-2 on regulatory CD4+ T cell frequency and function in melanoma patients vaccinated with HLA-class I peptides: impact on the antigen-specific T cell response.
Camisaschi C, Filipazzi P, Tazzari M, Casati C, Beretta V, Pilla L, Patuzzo R, Maurichi A, Cova A, Maio M, Chiarion-Sileni V, Tragni G, Santinami M, Vergani B, Villa A, Berti E, Umansky L, Beckhove P, Umansky V, Parmiani G, Rivoltini L, Castelli C
Cancer immunology, immunotherapy : CII 2013 May;62(5):897-908
Cancer immunology, immunotherapy : CII 2013 May;62(5):897-908
Allelic exclusion and peripheral reconstitution by TCR transgenic T cells arising from transduced human hematopoietic stem/progenitor cells.
Giannoni F, Hardee CL, Wherley J, Gschweng E, Senadheera S, Kaufman ML, Chan R, Bahner I, Gersuk V, Wang X, Gjertson D, Baltimore D, Witte ON, Economou JS, Ribas A, Kohn DB
Molecular therapy : the journal of the American Society of Gene Therapy 2013 May;21(5):1044-54
Molecular therapy : the journal of the American Society of Gene Therapy 2013 May;21(5):1044-54
Discovering naturally processed antigenic determinants that confer protective T cell immunity.
Gilchuk P, Spencer CT, Conant SB, Hill T, Gray JJ, Niu X, Zheng M, Erickson JJ, Boyd KL, McAfee KJ, Oseroff C, Hadrup SR, Bennink JR, Hildebrand W, Edwards KM, Crowe JE Jr, Williams JV, Buus S, Sette A, Schumacher TN, Link AJ, Joyce S
The Journal of clinical investigation 2013 May;123(5):1976-87
The Journal of clinical investigation 2013 May;123(5):1976-87
Reduced varicella-zoster-virus (VZV)-specific lymphocytes and IgG antibody avidity in solid organ transplant recipients.
Prelog M, Schönlaub J, Jeller V, Almanzar G, Höfner K, Gruber S, Eiwegger T, Würzner R
Vaccine 2013 May 7;31(20):2420-6
Vaccine 2013 May 7;31(20):2420-6
T cell memory to evolutionarily conserved and shared hemagglutinin epitopes of H1N1 viruses: a pilot scale study.
Duvvuri VR, Duvvuri B, Jamnik V, Gubbay JB, Wu J, Wu GE
BMC infectious diseases 2013 May 4;13:204
BMC infectious diseases 2013 May 4;13:204
Comprehensive analysis of dengue virus-specific responses supports an HLA-linked protective role for CD8+ T cells.
Weiskopf D, Angelo MA, de Azeredo EL, Sidney J, Greenbaum JA, Fernando AN, Broadwater A, Kolla RV, De Silva AD, de Silva AM, Mattia KA, Doranz BJ, Grey HM, Shresta S, Peters B, Sette A
Proceedings of the National Academy of Sciences of the United States of America 2013 May 28;110(22):E2046-53
Proceedings of the National Academy of Sciences of the United States of America 2013 May 28;110(22):E2046-53
Differential targeting of viral components by CD4+ versus CD8+ T lymphocytes in dengue virus infection.
Rivino L, Kumaran EA, Jovanovic V, Nadua K, Teo EW, Pang SW, Teo GH, Gan VC, Lye DC, Leo YS, Hanson BJ, Smith KG, Bertoletti A, Kemeny DM, MacAry PA
Journal of virology 2013 Mar;87(5):2693-706
Journal of virology 2013 Mar;87(5):2693-706
Thalidomide maintenance therapy maturates the T cell compartment and compromises antigen-specific antitumor immunity in patients with multiple myeloma.
Herth I, Witzens-Harig M, Beckhove P, Hose D, Meissner T, Neuber B, Engelhardt M, Haas J, Neben K, Ho AD, Klein B, Goldschmidt H, Hundemer M
Experimental hematology 2013 Mar;41(3):231-40
Experimental hematology 2013 Mar;41(3):231-40
Human leucocyte antigen-Bw4 and Gag-specific T cell responses are associated with slow disease progression in HIV-1B-infected anti-retroviral therapy-naive Chinese.
Li WH, Li CY, Yang HB, Zhang HP, Zhang X, Kong LS, Xu XN, Lu SC, Yan HP
Clinical and experimental immunology 2013 Mar;171(3):298-306
Clinical and experimental immunology 2013 Mar;171(3):298-306
In vitro diagnostic assays are effective during the acute phase of delayed-type drug hypersensitivity reactions.
Polak ME, Belgi G, McGuire C, Pickard C, Healy E, Friedmann PS, Ardern-Jones MR
The British journal of dermatology 2013 Mar;168(3):539-49
The British journal of dermatology 2013 Mar;168(3):539-49
Oral administration of an adenovirus vector encoding both an avian influenza A hemagglutinin and a TLR3 ligand induces antigen specific granzyme B and IFN-γ T cell responses in humans.
Peters W, Brandl JR, Lindbloom JD, Martinez CJ, Scallan CD, Trager GR, Tingley DW, Kabongo ML, Tucker SN
Vaccine 2013 Mar 25;31(13):1752-8
Vaccine 2013 Mar 25;31(13):1752-8
HLA-restricted CTL that are specific for the immune checkpoint ligand PD-L1 occur with high frequency in cancer patients.
Munir S, Andersen GH, Met Ö, Donia M, Frøsig TM, Larsen SK, Klausen TW, Svane IM, Andersen MH
Cancer research 2013 Mar 15;73(6):1764-76
Cancer research 2013 Mar 15;73(6):1764-76
Long-term survival after adoptive bone marrow T cell therapy of advanced metastasized breast cancer: follow-up analysis of a clinical pilot trial.
Domschke C, Ge Y, Bernhardt I, Schott S, Keim S, Juenger S, Bucur M, Mayer L, Blumenstein M, Rom J, Heil J, Sohn C, Schneeweiss A, Beckhove P, Schuetz F
Cancer immunology, immunotherapy : CII 2013 Jun;62(6):1053-60
Cancer immunology, immunotherapy : CII 2013 Jun;62(6):1053-60
Rapid expansion of T cells: Effects of culture and cryopreservation and importance of short-term cell recovery.
Sadeghi A, Ullenhag G, Wagenius G, Tötterman TH, Eriksson F
Acta oncologica (Stockholm, Sweden) 2013 Jun;52(5):978-86
Acta oncologica (Stockholm, Sweden) 2013 Jun;52(5):978-86
Complement opsonization of HIV-1 results in a different intracellular processing pattern and enhanced MHC class I presentation by dendritic cells.
Tjomsland V, Ellegård R, Burgener A, Mogk K, Che KF, Westmacott G, Hinkula J, Lifson JD, Larsson M
European journal of immunology 2013 Jun;43(6):1470-83
European journal of immunology 2013 Jun;43(6):1470-83
Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells.
Robbins PF, Lu YC, El-Gamil M, Li YF, Gross C, Gartner J, Lin JC, Teer JK, Cliften P, Tycksen E, Samuels Y, Rosenberg SA
Nature medicine 2013 Jun;19(6):747-52
Nature medicine 2013 Jun;19(6):747-52
Silencing of the glucocorticoid-induced leucine zipper improves the immunogenicity of clinical-grade dendritic cells.
Cathelin D, Met Ö, Svane IM
Cytotherapy 2013 Jun;15(6):740-9
Cytotherapy 2013 Jun;15(6):740-9
CD141+ dendritic cells produce prominent amounts of IFN-α after dsRNA recognition and can be targeted via DEC-205 in humanized mice.
Meixlsperger S, Leung CS, Rämer PC, Pack M, Vanoaica LD, Breton G, Pascolo S, Salazar AM, Dzionek A, Schmitz J, Steinman RM, Münz C
Blood 2013 Jun 20;121(25):5034-44
Blood 2013 Jun 20;121(25):5034-44
β-Lactam antibiotics form distinct haptenic structures on albumin and activate drug-specific T-lymphocyte responses in multiallergic patients with cystic fibrosis.
Jenkins RE, Yaseen FS, Monshi MM, Whitaker P, Meng X, Farrell J, Hamlett J, Sanderson JP, El-Ghaiesh S, Peckham D, Pirmohamed M, Park BK, Naisbitt DJ
Chemical research in toxicology 2013 Jun 17;26(6):963-75
Chemical research in toxicology 2013 Jun 17;26(6):963-75
HLA Class II tetramers reveal tissue-specific regulatory T cells that suppress T-cell responses in breast carcinoma patients.
Schmidt HH, Ge Y, Hartmann FJ, Conrad H, Klug F, Nittel S, Bernhard H, Domschke C, Schuetz F, Sohn C, Beckhove P
Oncoimmunology 2013 Jun 1;2(6):e24962
Oncoimmunology 2013 Jun 1;2(6):e24962
Hierarchy of CD4 T cell epitopes of the ANRS Lipo5 synthetic vaccine relies on the frequencies of pre-existing peptide-specific T cells in healthy donors.
Castelli FA, Szely N, Olivain A, Casartelli N, Grygar C, Schneider A, Besse A, Levy Y, Schwartz O, Maillère B
Journal of immunology (Baltimore, Md. : 1950) 2013 Jun 1;190(11):5757-63
Journal of immunology (Baltimore, Md. : 1950) 2013 Jun 1;190(11):5757-63
HLA-B*44 is associated with a lower viral set point and slow CD4 decline in a cohort of Chinese homosexual men acutely infected with HIV-1.
Zhang X, Huang X, Xia W, Li W, Zhang T, Wu H, Xu X, Yan H
Clinical and vaccine immunology : CVI 2013 Jul;20(7):1048-54
Clinical and vaccine immunology : CVI 2013 Jul;20(7):1048-54
A conserved human T cell population targets mycobacterial antigens presented by CD1b.
Van Rhijn I, Kasmar A, de Jong A, Gras S, Bhati M, Doorenspleet ME, de Vries N, Godfrey DI, Altman JD, de Jager W, Rossjohn J, Moody DB
Nature immunology 2013 Jul;14(7):706-13
Nature immunology 2013 Jul;14(7):706-13
Therapeutic targeting of regulatory T cells enhances tumor-specific CD8+ T cell responses in Epstein-Barr virus associated nasopharyngeal carcinoma.
Fogg M, Murphy JR, Lorch J, Posner M, Wang F
Virology 2013 Jul 5;441(2):107-13
Virology 2013 Jul 5;441(2):107-13
Serum IL-10 as a marker of severe dengue infection.
Malavige GN, Gomes L, Alles L, Chang T, Salimi M, Fernando S, Nanayakkara KD, Jayaratne S, Ogg GS
BMC infectious diseases 2013 Jul 24;13:341
BMC infectious diseases 2013 Jul 24;13:341
HLA peptide length preferences control CD8+ T cell responses.
Rist MJ, Theodossis A, Croft NP, Neller MA, Welland A, Chen Z, Sullivan LC, Burrows JM, Miles JJ, Brennan RM, Gras S, Khanna R, Brooks AG, McCluskey J, Purcell AW, Rossjohn J, Burrows SR
Journal of immunology (Baltimore, Md. : 1950) 2013 Jul 15;191(2):561-71
Journal of immunology (Baltimore, Md. : 1950) 2013 Jul 15;191(2):561-71
Hepatitis B virus (HBV)-specific T-cell responses to recombinant HBV core protein in patients with normal liver function and co-infected with chronic HBV and human immunodeficiency virus 1 (HIV-1).
Zhang X, Xing H, Feng X, Zhang H, Wang Y, Yan H
Virology journal 2013 Jul 12;10:232
Virology journal 2013 Jul 12;10:232
Melanoma-educated CD14+ cells acquire a myeloid-derived suppressor cell phenotype through COX-2-dependent mechanisms.
Mao Y, Poschke I, Wennerberg E, Pico de Coaña Y, Egyhazi Brage S, Schultz I, Hansson J, Masucci G, Lundqvist A, Kiessling R
Cancer research 2013 Jul 1;73(13):3877-87
Cancer research 2013 Jul 1;73(13):3877-87
Interleukin-10 spot-forming cells as a novel biomarker of chronic graft-versus-host disease.
Hirayama M, Azuma E, Nakagawa-Nakazawa A, Kumamoto T, Iwamoto S, Amano K, Tamaki S, Usui E, Komada Y
Haematologica 2013 Jan;98(1):41-9
Haematologica 2013 Jan;98(1):41-9
The potential of using enzyme-linked immunospot to diagnose cephalosporin-induced maculopapular exanthems.
Tanvarasethee B, Buranapraditkun S, Klaewsongkram J
Acta dermato-venereologica 2013 Jan;93(1):66-9
Acta dermato-venereologica 2013 Jan;93(1):66-9
Memory T cells in latent Mycobacterium tuberculosis infection are directed against three antigenic islands and largely contained in a CXCR3+CCR6+ Th1 subset.
Lindestam Arlehamn CS, Gerasimova A, Mele F, Henderson R, Swann J, Greenbaum JA, Kim Y, Sidney J, James EA, Taplitz R, McKinney DM, Kwok WW, Grey H, Sallusto F, Peters B, Sette A
PLoS pathogens 2013 Jan;9(1):e1003130
PLoS pathogens 2013 Jan;9(1):e1003130
A novel human autoantigen, endothelial cell growth factor, is a target of T and B cell responses in patients with Lyme disease.
Drouin EE, Seward RJ, Strle K, McHugh G, Katchar K, Londoño D, Yao C, Costello CE, Steere AC
Arthritis and rheumatism 2013 Jan;65(1):186-96
Arthritis and rheumatism 2013 Jan;65(1):186-96
Sipuleucel-T immune parameters correlate with survival: an analysis of the randomized phase 3 clinical trials in men with castration-resistant prostate cancer.
Sheikh NA, Petrylak D, Kantoff PW, Dela Rosa C, Stewart FP, Kuan LY, Whitmore JB, Trager JB, Poehlein CH, Frohlich MW, Urdal DL
Cancer immunology, immunotherapy : CII 2013 Jan;62(1):137-47
Cancer immunology, immunotherapy : CII 2013 Jan;62(1):137-47
Short communication: broader T cell responses directed against human immunodeficiency virus type 1 in infected Chinese individuals through blood-borne transmission in comparison with mucosal transmission.
Zhou D, Zhang X, Li W, Xu X, Goonetilleke N, Yang H, Dong T, Yan H
AIDS research and human retroviruses 2013 Jan;29(1):89-93
AIDS research and human retroviruses 2013 Jan;29(1):89-93
Enhanced function of redirected human T cells expressing linker for activation of T cells that is resistant to ubiquitylation.
Kunii N, Zhao Y, Jiang S, Liu X, Scholler J, Balagopalan L, Samelson LE, Milone MC, June CH
Human gene therapy 2013 Jan;24(1):27-37
Human gene therapy 2013 Jan;24(1):27-37
Vertical T cell immunodominance and epitope entropy determine HIV-1 escape.
Liu MK, Hawkins N, Ritchie AJ, Ganusov VV, Whale V, Brackenridge S, Li H, Pavlicek JW, Cai F, Rose-Abrahams M, Treurnicht F, Hraber P, Riou C, Gray C, Ferrari G, Tanner R, Ping LH, Anderson JA, Swanstrom R, CHAVI Core B, Cohen M, Karim SS, Haynes B, Borrow P, Perelson AS, Shaw GM, Hahn BH, Williamson C, Korber BT, Gao F, Self S, McMichael A, Goonetilleke N
The Journal of clinical investigation 2013 Jan;123(1):380-93
The Journal of clinical investigation 2013 Jan;123(1):380-93
Functional single-cell analysis of T-cell activation by supported lipid bilayer-tethered ligands on arrays of nanowells.
Torres AJ, Contento RL, Gordo S, Wucherpfennig KW, Love JC
Lab on a chip 2013 Jan 7;13(1):90-9
Lab on a chip 2013 Jan 7;13(1):90-9
CD8+ T Lymphocyte Epitopes From The Herpes Simplex Virus Type 2 ICP27, VP22 and VP13/14 Proteins To Facilitate Vaccine Design And Characterization.
Platt RJ, Khodai T, Townend TJ, Bright HH, Cockle P, Perez-Tosar L, Webster R, Champion B, Hickling TP, Mirza F
Cells 2013 Jan 4;2(1):19-42
Cells 2013 Jan 4;2(1):19-42
Poor HIV control in HLA-B*27 and B*57/58 noncontrollers is associated with limited number of polyfunctional Gag p24-specific CD8+ T cells.
Techakriengkrai N, Tansiri Y, Hansasuta P
AIDS (London, England) 2013 Jan 2;27(1):17-27
AIDS (London, England) 2013 Jan 2;27(1):17-27
Lipoproteins are major targets of the polyclonal human T cell response to Mycobacterium tuberculosis.
Seshadri C, Turner MT, Lewinsohn DM, Moody DB, Van Rhijn I
Journal of immunology (Baltimore, Md. : 1950) 2013 Jan 1;190(1):278-84
Journal of immunology (Baltimore, Md. : 1950) 2013 Jan 1;190(1):278-84
Distinct HIV-1 escape patterns selected by cytotoxic T cells with identical epitope specificity.
Yagita Y, Kuse N, Kuroki K, Gatanaga H, Carlson JM, Chikata T, Brumme ZL, Murakoshi H, Akahoshi T, Pfeifer N, Mallal S, John M, Ose T, Matsubara H, Kanda R, Fukunaga Y, Honda K, Kawashima Y, Ariumi Y, Oka S, Maenaka K, Takiguchi M
Journal of virology 2013 Feb;87(4):2253-63
Journal of virology 2013 Feb;87(4):2253-63
Herpes simplex virus 2 (HSV-2) prevents dendritic cell maturation, induces apoptosis, and triggers release of proinflammatory cytokines: potential links to HSV-HIV synergy.
Stefanidou M, Ramos I, Mas Casullo V, Trépanier JB, Rosenbaum S, Fernandez-Sesma A, Herold BC
Journal of virology 2013 Feb;87(3):1443-53
Journal of virology 2013 Feb;87(3):1443-53
CD40L-Tri, a novel formulation of recombinant human CD40L that effectively activates B cells.
Naito M, Hainz U, Burkhardt UE, Fu B, Ahove D, Stevenson KE, Rajasagi M, Zhu B, Alonso A, Witten E, Matsuoka K, Neuberg D, Duke-Cohan JS, Wu CJ, Freeman GJ
Cancer immunology, immunotherapy : CII 2013 Feb;62(2):347-57
Cancer immunology, immunotherapy : CII 2013 Feb;62(2):347-57
Human leukocyte antigen (HLA)-B*57:01-restricted activation of drug-specific T cells provides the immunological basis for flucloxacillin-induced liver injury.
Monshi MM, Faulkner L, Gibson A, Jenkins RE, Farrell J, Earnshaw CJ, Alfirevic A, Cederbrant K, Daly AK, French N, Pirmohamed M, Park BK, Naisbitt DJ
Hepatology (Baltimore, Md.) 2013 Feb;57(2):727-39
Hepatology (Baltimore, Md.) 2013 Feb;57(2):727-39
A rationally engineered anti-HIV peptide fusion inhibitor with greatly reduced immunogenicity.
Brauer F, Schmidt K, Zahn RC, Richter C, Radeke HH, Schmitz JE, von Laer D, Egerer L
Antimicrobial agents and chemotherapy 2013 Feb;57(2):679-88
Antimicrobial agents and chemotherapy 2013 Feb;57(2):679-88
Relationship between chemokine receptor expression, chemokine levels and HIV-1 replication in the lungs of persons exposed to Mycobacterium tuberculosis.
Kalsdorf B, Skolimowska KH, Scriba TJ, Dawson R, Dheda K, Wood K, Hofmeister J, Hanekom WA, Lange C, Wilkinson RJ
European journal of immunology 2013 Feb;43(2):540-9
European journal of immunology 2013 Feb;43(2):540-9
Cancer regression and neurological toxicity following anti-MAGE-A3 TCR gene therapy.
Morgan RA, Chinnasamy N, Abate-Daga D, Gros A, Robbins PF, Zheng Z, Dudley ME, Feldman SA, Yang JC, Sherry RM, Phan GQ, Hughes MS, Kammula US, Miller AD, Hessman CJ, Stewart AA, Restifo NP, Quezado MM, Alimchandani M, Rosenberg AZ, Nath A, Wang T, Bielekova B, Wuest SC, Akula N, McMahon FJ, Wilde S, Mosetter B, Schendel DJ, Laurencot CM, Rosenberg SA
Journal of immunotherapy (Hagerstown, Md. : 1997) 2013 Feb;36(2):133-51
Journal of immunotherapy (Hagerstown, Md. : 1997) 2013 Feb;36(2):133-51
Adults 65 years old and older have reduced numbers of functional memory T cells to respiratory syncytial virus fusion protein.
Cherukuri A, Patton K, Gasser RA Jr, Zuo F, Woo J, Esser MT, Tang RS
Clinical and vaccine immunology : CVI 2013 Feb;20(2):239-47
Clinical and vaccine immunology : CVI 2013 Feb;20(2):239-47
Comparing the safety and immunogenicity of a candidate TB vaccine MVA85A administered by intramuscular and intradermal delivery.
Meyer J, Harris SA, Satti I, Poulton ID, Poyntz HC, Tanner R, Rowland R, Griffiths KL, Fletcher HA, McShane H
Vaccine 2013 Feb 4;31(7):1026-33
Vaccine 2013 Feb 4;31(7):1026-33
SHP2 is overexpressed and inhibits pSTAT1-mediated APM component expression, T-cell attracting chemokine secretion, and CTL recognition in head and neck cancer cells.
Leibowitz MS, Srivastava RM, Andrade Filho PA, Egloff AM, Wang L, Seethala RR, Ferrone S, Ferris RL
Clinical cancer research : an official journal of the American Association for Cancer Research 2013 Feb 15;19(4):798-808
Clinical cancer research : an official journal of the American Association for Cancer Research 2013 Feb 15;19(4):798-808
Epstein-Barr virus coinfection in children boosts cytomegalovirus-induced differentiation of natural killer cells.
Saghafian-Hedengren S, Sohlberg E, Theorell J, Carvalho-Queiroz C, Nagy N, Persson JO, Nilsson C, Bryceson YT, Sverremark-Ekström E
Journal of virology 2013 Dec;87(24):13446-55
Journal of virology 2013 Dec;87(24):13446-55
Decreased HPV-specific T cell responses and accumulation of immunosuppressive influences in oropharyngeal cancer patients following radical therapy.
Al-Taei S, Banner R, Powell N, Evans M, Palaniappan N, Tabi Z, Man S
Cancer immunology, immunotherapy : CII 2013 Dec;62(12):1821-30
Cancer immunology, immunotherapy : CII 2013 Dec;62(12):1821-30
CD8(+) T-cell priming and boosting: more antigen-presenting DC, or more antigen per DC?
Schaft N, Wellner V, Wohn C, Schuler G, Dörrie J
Cancer immunology, immunotherapy : CII 2013 Dec;62(12):1769-80
Cancer immunology, immunotherapy : CII 2013 Dec;62(12):1769-80
Functional characterization of Foxp3-specific spontaneous immune responses.
Larsen SK, Munir S, Woetmann A, Frøsig TM, Odum N, Svane IM, Becker JC, Andersen MH
Leukemia 2013 Dec;27(12):2332-40
Leukemia 2013 Dec;27(12):2332-40
The MAPK pathway is a predominant regulator of HLA-A expression in esophageal and gastric cancer.
Mimura K, Shiraishi K, Mueller A, Izawa S, Kua LF, So J, Yong WP, Fujii H, Seliger B, Kiessling R, Kono K
Journal of immunology (Baltimore, Md. : 1950) 2013 Dec 15;191(12):6261-72
Journal of immunology (Baltimore, Md. : 1950) 2013 Dec 15;191(12):6261-72
Cytomegalovirus-seropositive children show inhibition of in vitro EBV infection that is associated with CD8+CD57+ T cell enrichment and IFN-γ.
Sohlberg E, Saghafian-Hedengren S, Rasul E, Marchini G, Nilsson C, Klein E, Nagy N, Sverremark-Ekström E
Journal of immunology (Baltimore, Md. : 1950) 2013 Dec 1;191(11):5669-76
Journal of immunology (Baltimore, Md. : 1950) 2013 Dec 1;191(11):5669-76
Quantitative and qualitative differences in the T cell response to HIV in uninfected Ugandans exposed or unexposed to HIV-infected partners.
Pala P, Serwanga J, Watera C, Ritchie AJ, Moodie Z, Wang M, Goonetilleke N, Birabwa E, Hughes P, Senkaali D, Nakiboneka R, Grosskurth H, Haynes B, McMichael A, Kaleebu P, Center for HIV/AIDS Vaccine Immunology
Journal of virology 2013 Aug;87(16):9053-63
Journal of virology 2013 Aug;87(16):9053-63
Prenatal maternal anxiety predicts reduced adaptive immunity in infants.
O'Connor TG, Winter MA, Hunn J, Carnahan J, Pressman EK, Glover V, Robertson-Blackmore E, Moynihan JA, Lee FE, Caserta MT
Brain, behavior, and immunity 2013 Aug;32:21-8
Brain, behavior, and immunity 2013 Aug;32:21-8
Experimental respiratory Marburg virus haemorrhagic fever infection in the common marmoset (Callithrix jacchus).
Smither SJ, Nelson M, Eastaugh L, Laws TR, Taylor C, Smith SA, Salguero FJ, Lever MS
International journal of experimental pathology 2013 Apr;94(2):156-68
International journal of experimental pathology 2013 Apr;94(2):156-68
Serum-free freezing media support high cell quality and excellent ELISPOT assay performance across a wide variety of different assay protocols.
Filbert H, Attig S, Bidmon N, Renard BY, Janetzki S, Sahin U, Welters MJ, Ottensmeier C, van der Burg SH, Gouttefangeas C, Britten CM
Cancer immunology, immunotherapy : CII 2013 Apr;62(4):615-27
Cancer immunology, immunotherapy : CII 2013 Apr;62(4):615-27
CD1c tetramers detect ex vivo T cell responses to processed phosphomycoketide antigens.
Ly D, Kasmar AG, Cheng TY, de Jong A, Huang S, Roy S, Bhatt A, van Summeren RP, Altman JD, Jacobs WR Jr, Adams EJ, Minnaard AJ, Porcelli SA, Moody DB
The Journal of experimental medicine 2013 Apr 8;210(4):729-41
The Journal of experimental medicine 2013 Apr 8;210(4):729-41
Glycosylphosphatidylinositol-specific, CD1d-restricted T cells in paroxysmal nocturnal hemoglobinuria.
Gargiulo L, Papaioannou M, Sica M, Talini G, Chaidos A, Richichi B, Nikolaev AV, Nativi C, Layton M, de la Fuente J, Roberts I, Luzzatto L, Notaro R, Karadimitris A
Blood 2013 Apr 4;121(14):2753-61
Blood 2013 Apr 4;121(14):2753-61
Phase I clinical trial of human vascular endothelial growth factor receptor 1 peptide vaccines for patients with metastatic renal cell carcinoma.
Yoshimura K, Minami T, Nozawa M, Uemura H
British journal of cancer 2013 Apr 2;108(6):1260-6
British journal of cancer 2013 Apr 2;108(6):1260-6
Long-term Vaccination with Multiple Peptides Derived from Cancer-Testis Antigens Can Maintain a Specific T-cell Response and Achieve Disease Stability in Advanced Biliary Tract Cancer.
Aruga A, Takeshita N, Kotera Y, Okuyama R, Matsushita N, Ohta T, Takeda K, Yamamoto M
Clinical cancer research : an official journal of the American Association for Cancer Research 2013 Apr 15;19(8):2224-31
Clinical cancer research : an official journal of the American Association for Cancer Research 2013 Apr 15;19(8):2224-31
Multiple therapeutic peptide vaccines consisting of combined novel cancer testis antigens and anti-angiogenic peptides for patients with non-small cell lung cancer.
Suzuki H, Fukuhara M, Yamaura T, Mutoh S, Okabe N, Yaginuma H, Hasegawa T, Yonechi A, Osugi J, Hoshino M, Kimura T, Higuchi M, Shio Y, Ise K, Takeda K, Gotoh M
Journal of translational medicine 2013 Apr 11;11:97
Journal of translational medicine 2013 Apr 11;11:97
The immune checkpoint regulator PD-L1 is a specific target for naturally occurring CD4(+) T cells.
Munir S, Andersen GH, Svane IM, Andersen MH
Oncoimmunology 2013 Apr 1;2(4):e23991
Oncoimmunology 2013 Apr 1;2(4):e23991
The EBV immunoevasins vIL-10 and BNLF2a protect newly infected B cells from immune recognition and elimination.
Jochum S, Moosmann A, Lang S, Hammerschmidt W, Zeidler R
PLoS pathogens 2012;8(5):e1002704
PLoS pathogens 2012;8(5):e1002704
Recovered patients with Stevens-Johson syndrome and toxic epidermal necrolysis maintain long-lived IFN-γ and sFasL memory response.
Fu M, Gao Y, Pan Y, Li W, Liao W, Wang G, Li C, Li C, Gao T, Liu Y
PloS one 2012;7(9):e45516
PloS one 2012;7(9):e45516
MRKAd5 HIV-1 Gag/Pol/Nef vaccine-induced T-cell responses inadequately predict distance of breakthrough HIV-1 sequences to the vaccine or viral load.
Janes H, Frahm N, DeCamp A, Rolland M, Gabriel E, Wolfson J, Hertz T, Kallas E, Goepfert P, Friedrich DP, Corey L, Mullins JI, McElrath MJ, Gilbert P
PloS one 2012;7(8):e43396
PloS one 2012;7(8):e43396
HIV-1 envelope resistance to proteasomal cleavage: implications for vaccine induced immune responses.
Steers NJ, Ratto-Kim S, de Souza MS, Currier JR, Kim JH, Michael NL, Alving CR, Rao M
PloS one 2012;7(8):e42579
PloS one 2012;7(8):e42579
Estimating point and interval frequency of antigen-specific CD4+ T cells based on short in vitro expansion and improved poisson distribution analysis.
Di Lullo G, Ieva F, Longhi R, Paganoni AM, Protti MP
PloS one 2012;7(8):e42340
PloS one 2012;7(8):e42340
Pertussis circulation has increased T-cell immunity during childhood more than a second acellular booster vaccination in Dutch children 9 years of age.
Schure RM, de Rond L, Oztürk K, Hendrikx L, Sanders E, Berbers G, Buisman AM
PloS one 2012;7(7):e41928
PloS one 2012;7(7):e41928
The effect of HLA polymorphisms on the recognition of Gag epitopes in HIV-1 CRF01_AE infection.
Sriwanthana B, Mori M, Tanaka M, Nishimura S, Miura T, Pathipvanich P, Sawanpanyalert P, Ariyoshi K
PloS one 2012;7(7):e41696
PloS one 2012;7(7):e41696
Distinct effector memory CD4+ T cell signatures in latent Mycobacterium tuberculosis infection, BCG vaccination and clinically resolved tuberculosis.
Adekambi T, Ibegbu CC, Kalokhe AS, Yu T, Ray SM, Rengarajan J
PloS one 2012;7(4):e36046
PloS one 2012;7(4):e36046
Natural CD4+ T-cell responses against indoleamine 2,3-dioxygenase.
Munir S, Larsen SK, Iversen TZ, Donia M, Klausen TW, Svane IM, Straten PT, Andersen MH
PloS one 2012;7(4):e34568
PloS one 2012;7(4):e34568
Low-replicating viruses and strong anti-viral immune response associated with prolonged disease control in a superinfected HIV-1 LTNP elite controller.
Pernas M, Casado C, Arcones C, Llano A, Sánchez-Merino V, Mothe B, Vicario JL, Grau E, Ruiz L, Sánchez J, Telenti A, Yuste E, Brander C, Galíndez CL
PloS one 2012;7(2):e31928
PloS one 2012;7(2):e31928
Revisiting the effect of acute P. falciparum malaria on Epstein-Barr virus: host balance in the setting of reduced malaria endemicity.
Jayasooriya S, Hislop A, Peng Y, Croom-Carter D, Jankey Y, Bell A, Dong T, Rowland-Jones S, Rickinson A, Walther M, Whittle H
PloS one 2012;7(2):e31142
PloS one 2012;7(2):e31142
Differential expression of CD96 surface molecule represents CD8⁺ T cells with dissimilar effector function during HIV-1 infection.
Eriksson EM, Keh CE, Deeks SG, Martin JN, Hecht FM, Nixon DF
PloS one 2012;7(12):e51696
PloS one 2012;7(12):e51696
Early-life gut bacteria associate with IL-4-, IL-10- and IFN-γ production at two years of age.
Johansson MA, Saghafian-Hedengren S, Haileselassie Y, Roos S, Troye-Blomberg M, Nilsson C, Sverremark-Ekström E
PloS one 2012;7(11):e49315
PloS one 2012;7(11):e49315
Generation and characterization of a defective HIV-1 Virus as an immunogen for a therapeutic vaccine.
Álvarez-Fernández C, Crespo Guardo A, García-Pérez J, García F, Blanco J, Escribà-García L, Gatell JM, Alcamí J, Plana M, Sánchez-Palomino S
PloS one 2012;7(11):e48848
PloS one 2012;7(11):e48848
Biomarkers of Plasmodium falciparum infection during pregnancy in women living in northeastern Tanzania.
Boström S, Ibitokou S, Oesterholt M, Schmiegelow C, Persson JO, Minja D, Lusingu J, Lemnge M, Fievet N, Deloron P, Luty AJ, Troye-Blomberg M
PloS one 2012;7(11):e48763
PloS one 2012;7(11):e48763
Fragmentation of SIV-gag vaccine induces broader T cell responses.
Benlahrech A, Meiser A, Herath S, Papagatsias T, Athanasopoulos T, Li F, Self S, Bachy V, Hervouet C, Logan K, Klavinskis L, Dickson G, Patterson S
PloS one 2012;7(10):e48038
PloS one 2012;7(10):e48038
CTL responses of high functional avidity and broad variant cross-reactivity are associated with HIV control.
Mothe B, Llano A, Ibarrondo J, Zamarreño J, Schiaulini M, Miranda C, Ruiz-Riol M, Berger CT, Herrero MJ, Palou E, Plana M, Rolland M, Khatri A, Heckerman D, Pereyra F, Walker BD, Weiner D, Paredes R, Clotet B, Felber BK, Pavlakis GN, Mullins JI, Brander C
PloS one 2012;7(1):e29717
PloS one 2012;7(1):e29717
PLGA nanoparticle-mediated delivery of tumor antigenic peptides elicits effective immune responses.
Ma W, Chen M, Kaushal S, McElroy M, Zhang Y, Ozkan C, Bouvet M, Kruse C, Grotjahn D, Ichim T, Minev B
International journal of nanomedicine 2012;7:1475-87
International journal of nanomedicine 2012;7:1475-87
Tumor associated antigen specific T-cell populations identified in ex vivo expanded TIL cultures.
Junker N, Kvistborg P, Køllgaard T, Straten Pt, Andersen MH, Svane IM
Cellular immunology 2012;273(1):1-9
Cellular immunology 2012;273(1):1-9
Human microRNA-1245 down-regulates the NKG2D receptor in natural killer cells and impairs NKG2D-mediated functions.
Espinoza JL, Takami A, Yoshioka K, Nakata K, Sato T, Kasahara Y, Nakao S
Haematologica 2012 Sep;97(9):1295-303
Haematologica 2012 Sep;97(9):1295-303
A human CD4+ T cell epitope in the influenza hemagglutinin is cross-reactive to influenza A virus subtypes and to influenza B virus.
Babon JA, Cruz J, Ennis FA, Yin L, Terajima M
Journal of virology 2012 Sep;86(17):9233-43
Journal of virology 2012 Sep;86(17):9233-43
The effect of chronological age on the inflammatory response of human fibroblasts.
Wolf J, Weinberger B, Arnold CR, Maier AB, Westendorp RG, Grubeck-Loebenstein B
Experimental gerontology 2012 Sep;47(9):749-53
Experimental gerontology 2012 Sep;47(9):749-53
HCV coinfection does not alter the frequency of regulatory T cells or CD8+ T cell immune activation in chronically infected HIV+ Chinese subjects.
Zhuang Y, Wei X, Li Y, Zhao K, Zhang J, Kang W, Sun Y
AIDS research and human retroviruses 2012 Sep;28(9):1044-51
AIDS research and human retroviruses 2012 Sep;28(9):1044-51
Ad3-hTERT-E1A, a fully serotype 3 oncolytic adenovirus, in patients with chemotherapy refractory cancer.
Hemminki O, Diaconu I, Cerullo V, Pesonen SK, Kanerva A, Joensuu T, Kairemo K, Laasonen L, Partanen K, Kangasniemi L, Lieber A, Pesonen S, Hemminki A
Molecular therapy : the journal of the American Society of Gene Therapy 2012 Sep;20(9):1821-30
Molecular therapy : the journal of the American Society of Gene Therapy 2012 Sep;20(9):1821-30
Comparison of in vivo Adjuvanticity of Liposomal PO CpG ODN with Liposomal PS CpG ODN: Soluble Leishmania Antigens as a Model.
Golali E, Jaafari MR, Khamesipour A, Abbasi A, Saberi Z, Badiee A
Iranian journal of basic medical sciences 2012 Sep;15(5):1032-45
Iranian journal of basic medical sciences 2012 Sep;15(5):1032-45
T cells engineered with a T cell receptor against the prostate antigen TARP specifically kill HLA-A2+ prostate and breast cancer cells.
Hillerdal V, Nilsson B, Carlsson B, Eriksson F, Essand M
Proceedings of the National Academy of Sciences of the United States of America 2012 Sep 25;109(39):15877-81
Proceedings of the National Academy of Sciences of the United States of America 2012 Sep 25;109(39):15877-81
Prolonged persistence of measles virus RNA is characteristic of primary infection dynamics.
Lin WH, Kouyos RD, Adams RJ, Grenfell BT, Griffin DE
Proceedings of the National Academy of Sciences of the United States of America 2012 Sep 11;109(37):14989-94
Proceedings of the National Academy of Sciences of the United States of America 2012 Sep 11;109(37):14989-94
Metastatic melanoma patients treated with dendritic cell vaccination, Interleukin-2 and metronomic cyclophosphamide: results from a phase II trial.
Ellebaek E, Engell-Noerregaard L, Iversen TZ, Froesig TM, Munir S, Hadrup SR, Andersen MH, Svane IM
Cancer immunology, immunotherapy : CII 2012 Oct;61(10):1791-804
Cancer immunology, immunotherapy : CII 2012 Oct;61(10):1791-804
Mutated BCR-ABL generates immunogenic T-cell epitopes in CML patients.
Cai A, Keskin DB, DeLuca DS, Alonso A, Zhang W, Zhang GL, Hammond NN, Nardi V, Stone RM, Neuberg D, Sidney J, Brusic V, Wu CJ
Clinical cancer research : an official journal of the American Association for Cancer Research 2012 Oct 15;18(20):5761-72
Clinical cancer research : an official journal of the American Association for Cancer Research 2012 Oct 15;18(20):5761-72
Detecting T-cell reactivity to whole cell vaccines: Proof of concept analysis of T-cell response to K562 cell antigens in CML patients.
Brusic A, Hainz U, Wadleigh M, Neuberg D, Su M, Canning CM, Deangelo DJ, Stone RM, Lee JS, Mulligan RC, Ritz J, Dranoff G, Sasada T, Wu CJ
Oncoimmunology 2012 Oct 1;1(7):1095-1103
Oncoimmunology 2012 Oct 1;1(7):1095-1103
Survivin-specific T-cell reactivity correlates with tumor response and patient survival: a phase-II peptide vaccination trial in metastatic melanoma.
Becker JC, Andersen MH, Hofmeister-Müller V, Wobser M, Frey L, Sandig C, Walter S, Singh-Jasuja H, Kämpgen E, Opitz A, Zapatka M, Bröcker EB, Thor Straten P, Schrama D, Ugurel S
Cancer immunology, immunotherapy : CII 2012 Nov;61(11):2091-103
Cancer immunology, immunotherapy : CII 2012 Nov;61(11):2091-103
Controlled-rate freezer cryopreservation of highly concentrated peripheral blood mononuclear cells results in higher cell yields and superior autologous T-cell stimulation for dendritic cell-based immunotherapy.
Buhl T, Legler TJ, Rosenberger A, Schardt A, Schön MP, Haenssle HA
Cancer immunology, immunotherapy : CII 2012 Nov;61(11):2021-31
Cancer immunology, immunotherapy : CII 2012 Nov;61(11):2021-31
The simultaneous ex vivo detection of low-frequency antigen-specific CD4+ and CD8+ T-cell responses using overlapping peptide pools.
Singh SK, Meyering M, Ramwadhdoebe TH, Stynenbosch LF, Redeker A, Kuppen PJ, Melief CJ, Welters MJ, van der Burg SH
Cancer immunology, immunotherapy : CII 2012 Nov;61(11):1953-63
Cancer immunology, immunotherapy : CII 2012 Nov;61(11):1953-63
HCV genotype-3a T cell immunity: specificity, function and impact of therapy.
Humphreys IS, von Delft A, Brown A, Hibbert L, Collier JD, Foster GR, Rahman M, Christian A, Klenerman P, Barnes E
Gut 2012 Nov;61(11):1589-99
Gut 2012 Nov;61(11):1589-99
Predominance of heterosubtypic IFN-γ-only-secreting effector memory T cells in pandemic H1N1 naive adults.
Sridhar S, Begom S, Bermingham A, Ziegler T, Roberts KL, Barclay WS, Openshaw P, Lalvani A
European journal of immunology 2012 Nov;42(11):2913-24
European journal of immunology 2012 Nov;42(11):2913-24
T-cell responses before and after the fifth consecutive acellular pertussis vaccination in 4-year-old Dutch children.
Schure RM, Hendrikx LH, de Rond LG, Oztürk K, Sanders EA, Berbers GA, Buisman AM
Clinical and vaccine immunology : CVI 2012 Nov;19(11):1879-86
Clinical and vaccine immunology : CVI 2012 Nov;19(11):1879-86
HIV-1-specific enzyme-linked immunosorbent spot assay responses in HIV-1-exposed uninfected partners in discordant relationships compared to those in low-risk controls.
Guthrie BL, Lohman-Payne B, Liu AY, Bosire R, Nuvor SV, Choi RY, Mackelprang RD, Kiarie JN, De Rosa SC, Richardson BA, John-Stewart GC, Farquhar C
Clinical and vaccine immunology : CVI 2012 Nov;19(11):1798-805
Clinical and vaccine immunology : CVI 2012 Nov;19(11):1798-805
Heteroclitic peptides enhance human immunodeficiency virus-specific CD8(+) T cell responses.
Gladney KH, Pohling J, Hollett NA, Zipperlen K, Gallant ME, Grant MD
Vaccine 2012 Nov 19;30(49):6997-7004
Vaccine 2012 Nov 19;30(49):6997-7004
Dendritic cell vaccination in glioblastoma after fluorescence-guided resection.
Valle RD, de Cerio AL, Inoges S, Tejada S, Pastor F, Villanueva H, Gallego J, Espinos J, Aristu J, Idoate MA, Andreu E, Bendandi M
World journal of clinical oncology 2012 Nov 10;3(11):142-9
World journal of clinical oncology 2012 Nov 10;3(11):142-9
Characterization of T-cell responses against IκBα in cancer patients.
Munir S, Frøsig TM, Hansen M, Svane IM, Andersen MH
Oncoimmunology 2012 Nov 1;1(8):1290-1296
Oncoimmunology 2012 Nov 1;1(8):1290-1296
Immunity to the melanoma inhibitor of apoptosis protein (ML-IAP; livin) in patients with malignant melanoma.
Zhou J, Yuen NK, Zhan Q, Velazquez EF, Murphy GF, Giobbie-Hurder A, Hodi FS
Cancer immunology, immunotherapy : CII 2012 May;61(5):655-65
Cancer immunology, immunotherapy : CII 2012 May;61(5):655-65
Safety and immunogenicity of vaccination with MART-1 (26-35, 27L), gp100 (209-217, 210M), and tyrosinase (368-376, 370D) in adjuvant with PF-3512676 and GM-CSF in metastatic melanoma.
Tarhini AA, Leng S, Moschos SJ, Yin Y, Sander C, Lin Y, Gooding WE, Kirkwood JM
Journal of immunotherapy (Hagerstown, Md. : 1997) 2012 May;35(4):359-66
Journal of immunotherapy (Hagerstown, Md. : 1997) 2012 May;35(4):359-66
Preferential CTL targeting of Gag is associated with relative viral control in long-term surviving HIV-1 infected former plasma donors from China.
Jia M, Hong K, Chen J, Ruan Y, Wang Z, Su B, Ren G, Zhang X, Liu Z, Zhao Q, Li D, Peng H, Altfeld M, Walker BD, Yu XG, Shao Y
Cell research 2012 May;22(5):903-14
Cell research 2012 May;22(5):903-14
Lower numbers of natural killer T cells in HIV-1 and Mycobacterium leprae co-infected patients.
Carvalho KI, Bruno FR, Snyder-Cappione JE, Maeda SM, Tomimori J, Xavier MB, Haslett PA, Nixon DF, Kallas EG
Immunology 2012 May;136(1):96-102
Immunology 2012 May;136(1):96-102
RNAs in Epstein-Barr virions control early steps of infection.
Jochum S, Ruiss R, Moosmann A, Hammerschmidt W, Zeidler R
Proceedings of the National Academy of Sciences of the United States of America 2012 May 22;109(21):E1396-404
Proceedings of the National Academy of Sciences of the United States of America 2012 May 22;109(21):E1396-404
Age of recipient and number of doses differentially impact human B and T cell immune memory responses to HPV vaccination.
Smolen KK, Gelinas L, Franzen L, Dobson S, Dawar M, Ogilvie G, Krajden M, Fortuno ES 3rd, Kollmann TR
Vaccine 2012 May 21;30(24):3572-9
Vaccine 2012 May 21;30(24):3572-9
The Thai phase III trial (RV144) vaccine regimen induces T cell responses that preferentially target epitopes within the V2 region of HIV-1 envelope.
de Souza MS, Ratto-Kim S, Chuenarom W, Schuetz A, Chantakulkij S, Nuntapinit B, Valencia-Micolta A, Thelian D, Nitayaphan S, Pitisuttithum P, Paris RM, Kaewkungwal J, Michael NL, Rerks-Ngarm S, Mathieson B, Marovich M, Currier JR, Kim JH, Ministry of Public Health–Thai AIDS Vaccine Evaluation Group Collaborators
Journal of immunology (Baltimore, Md. : 1950) 2012 May 15;188(10):5166-76
Journal of immunology (Baltimore, Md. : 1950) 2012 May 15;188(10):5166-76
Dissecting mechanisms of immunodominance to the common tuberculosis antigens ESAT-6, CFP10, Rv2031c (hspX), Rv2654c (TB7.7), and Rv1038c (EsxJ).
Arlehamn CS, Sidney J, Henderson R, Greenbaum JA, James EA, Moutaftsi M, Coler R, McKinney DM, Park D, Taplitz R, Kwok WW, Grey H, Peters B, Sette A
Journal of immunology (Baltimore, Md. : 1950) 2012 May 15;188(10):5020-31
Journal of immunology (Baltimore, Md. : 1950) 2012 May 15;188(10):5020-31
Human dendritic cells adenovirally-engineered to express three defined tumor antigens promote broad adaptive and innate immunity.
Blalock LT, Landsberg J, Messmer M, Shi J, Pardee AD, Haskell R, Vujanovic L, Kirkwood JM, Butterfield LH
Oncoimmunology 2012 May 1;1(3):287-357
Oncoimmunology 2012 May 1;1(3):287-357
A gynecologic oncology group phase II trial of two p53 peptide vaccine approaches: subcutaneous injection and intravenous pulsed dendritic cells in high recurrence risk ovarian cancer patients.
Rahma OE, Ashtar E, Czystowska M, Szajnik ME, Wieckowski E, Bernstein S, Herrin VE, Shams MA, Steinberg SM, Merino M, Gooding W, Visus C, Deleo AB, Wolf JK, Bell JG, Berzofsky JA, Whiteside TL, Khleif SN
Cancer immunology, immunotherapy : CII 2012 Mar;61(3):373-84
Cancer immunology, immunotherapy : CII 2012 Mar;61(3):373-84
Novel myeloma-associated antigens revealed in the context of syngeneic hematopoietic stem cell transplantation.
Biernacki MA, Tai YT, Zhang GL, Alonso A, Zhang W, Prabhala R, Zhang L, Munshi N, Neuberg D, Soiffer RJ, Ritz J, Alyea EP, Brusic V, Anderson KC, Wu CJ
Blood 2012 Mar 29;119(13):3142-50
Blood 2012 Mar 29;119(13):3142-50
The ganglioside antigen G(D2) is surface-expressed in Ewing sarcoma and allows for MHC-independent immune targeting.
Kailayangiri S, Altvater B, Meltzer J, Pscherer S, Luecke A, Dierkes C, Titze U, Leuchte K, Landmeier S, Hotfilder M, Dirksen U, Hardes J, Gosheger G, Juergens H, Rossig C
British journal of cancer 2012 Mar 13;106(6):1123-33
British journal of cancer 2012 Mar 13;106(6):1123-33
Effective treatment of metastatic forms of Epstein-Barr virus-associated nasopharyngeal carcinoma with a novel adenovirus-based adoptive immunotherapy.
Smith C, Tsang J, Beagley L, Chua D, Lee V, Li V, Moss DJ, Coman W, Chan KH, Nicholls J, Kwong D, Khanna R
Cancer research 2012 Mar 1;72(5):1116-25
Cancer research 2012 Mar 1;72(5):1116-25
Exploiting the mutanome for tumor vaccination.
Castle JC, Kreiter S, Diekmann J, Löwer M, van de Roemer N, de Graaf J, Selmi A, Diken M, Boegel S, Paret C, Koslowski M, Kuhn AN, Britten CM, Huber C, Türeci O, Sahin U
Cancer research 2012 Mar 1;72(5):1081-91
Cancer research 2012 Mar 1;72(5):1081-91
Vaccination with dendritic cells loaded with tumor apoptotic bodies (Apo-DC) in patients with chronic lymphocytic leukemia: effects of various adjuvants and definition of immune response criteria.
Palma M, Hansson L, Choudhury A, Näsman-Glaser B, Eriksson I, Adamson L, Rossmann E, Widén K, Horváth R, Kokhaei P, Vertuani S, Mellstedt H, Osterborg A
Cancer immunology, immunotherapy : CII 2012 Jun;61(6):865-79
Cancer immunology, immunotherapy : CII 2012 Jun;61(6):865-79
Altered serum pro-inflammatory cytokines in children with Down's syndrome.
Nateghi Rostami M, Douraghi M, Miramin Mohammadi A, Nikmanesh B
European cytokine network 2012 Jun;23(2):64-7
European cytokine network 2012 Jun;23(2):64-7
Therapeutic potential of transplanted placental mesenchymal stem cells in treating Chinese miniature pigs with acute liver failure.
Cao H, Yang J, Yu J, Pan Q, Li J, Zhou P, Li Y, Pan X, Li J, Wang Y, Li L
BMC medicine 2012 Jun 6;10:56
BMC medicine 2012 Jun 6;10:56
Drug hypersensitivity caused by alteration of the MHC-presented self-peptide repertoire.
Ostrov DA, Grant BJ, Pompeu YA, Sidney J, Harndahl M, Southwood S, Oseroff C, Lu S, Jakoncic J, de Oliveira CA, Yang L, Mei H, Shi L, Shabanowitz J, English AM, Wriston A, Lucas A, Phillips E, Mallal S, Grey HM, Sette A, Hunt DF, Buus S, Peters B
Proceedings of the National Academy of Sciences of the United States of America 2012 Jun 19;109(25):9959-64
Proceedings of the National Academy of Sciences of the United States of America 2012 Jun 19;109(25):9959-64
Humoral and cellular capsid-specific immune responses to adeno-associated virus type 1 in randomized healthy donors.
Veron P, Leborgne C, Monteilhet V, Boutin S, Martin S, Moullier P, Masurier C
Journal of immunology (Baltimore, Md. : 1950) 2012 Jun 15;188(12):6418-24
Journal of immunology (Baltimore, Md. : 1950) 2012 Jun 15;188(12):6418-24
Invariant natural killer T cells are not affected by lysosomal storage in patients with Niemann-Pick disease type C.
Speak AO, Platt N, Salio M, te Vruchte D, Smith DA, Shepherd D, Veerapen N, Besra GS, Yanjanin NM, Simmons L, Imrie J, Wraith JE, Lachmann RH, Hartung R, Runz H, Mengel E, Beck M, Hendriksz CJ, Porter FD, Cerundolo V, Platt FM
European journal of immunology 2012 Jul;42(7):1886-92
European journal of immunology 2012 Jul;42(7):1886-92
Human papillomavirus immunization is associated with increased expression of different innate immune regulatory receptors.
Colmenares V, Noyola DE, Monsiváis-Urenda A, Salgado-Bustamante M, Estrada-Capetillo L, González-Amaro R, Baranda L
Clinical and vaccine immunology : CVI 2012 Jul;19(7):1005-11
Clinical and vaccine immunology : CVI 2012 Jul;19(7):1005-11
Peptide-pulsed dendritic cell vaccination targeting interleukin-13 receptor α2 chain in recurrent malignant glioma patients with HLA-A*24/A*02 allele.
Iwami K, Shimato S, Ohno M, Okada H, Nakahara N, Sato Y, Yoshida J, Suzuki S, Nishikawa H, Shiku H, Natsume A, Wakabayashi T
Cytotherapy 2012 Jul;14(6):733-42
Cytotherapy 2012 Jul;14(6):733-42
Protective effect of human endogenous retrovirus K dUTPase variants on psoriasis susceptibility.
Lai OY, Chen H, Michaud HA, Hayashi G, Kuebler PJ, Hultman GK, Ariza ME, Williams MV, Batista MD, Nixon DF, Foerster J, Bowcock AM, Liao W
The Journal of investigative dermatology 2012 Jul;132(7):1833-40
The Journal of investigative dermatology 2012 Jul;132(7):1833-40
Multicenter, phase II clinical trial of cancer vaccination for advanced esophageal cancer with three peptides derived from novel cancer-testis antigens.
Kono K, Iinuma H, Akutsu Y, Tanaka H, Hayashi N, Uchikado Y, Noguchi T, Fujii H, Okinaka K, Fukushima R, Matsubara H, Ohira M, Baba H, Natsugoe S, Kitano S, Takeda K, Yoshida K, Tsunoda T, Nakamura Y
Journal of translational medicine 2012 Jul 9;10:141
Journal of translational medicine 2012 Jul 9;10:141
Human tissues contain CD141hi cross-presenting dendritic cells with functional homology to mouse CD103+ nonlymphoid dendritic cells.
Haniffa M, Shin A, Bigley V, McGovern N, Teo P, See P, Wasan PS, Wang XN, Malinarich F, Malleret B, Larbi A, Tan P, Zhao H, Poidinger M, Pagan S, Cookson S, Dickinson R, Dimmick I, Jarrett RF, Renia L, Tam J, Song C, Connolly J, Chan JK, Gehring A, Bertoletti A, Collin M, Ginhoux F
Immunity 2012 Jul 27;37(1):60-73
Immunity 2012 Jul 27;37(1):60-73
Analysis of T cell responses to the major allergens from German cockroach: epitope specificity and relationship to IgE production.
Oseroff C, Sidney J, Tripple V, Grey H, Wood R, Broide DH, Greenbaum J, Kolla R, Peters B, Pomés A, Sette A
Journal of immunology (Baltimore, Md. : 1950) 2012 Jul 15;189(2):679-88
Journal of immunology (Baltimore, Md. : 1950) 2012 Jul 15;189(2):679-88
Association of a functional Indoleamine 2,3-dioxygenase 2 genotype with specific immune responses.
Køllgaard T, Klausen TW, Idorn M, Holmgaard RB, Straten PT, Andersen MH
Oncoimmunology 2012 Jul 1;1(4):441-447
Oncoimmunology 2012 Jul 1;1(4):441-447
HIV-specific CD4 T cell responses to different viral proteins have discordant associations with viral load and clinical outcome.
Ranasinghe S, Flanders M, Cutler S, Soghoian DZ, Ghebremichael M, Davis I, Lindqvist M, Pereyra F, Walker BD, Heckerman D, Streeck H
Journal of virology 2012 Jan;86(1):277-83
Journal of virology 2012 Jan;86(1):277-83
HIV-1 infection alters CD4+ memory T-cell phenotype at the site of disease in extrapulmonary tuberculosis.
Matthews K, Ntsekhe M, Syed F, Scriba T, Russell J, Tibazarwa K, Deffur A, Hanekom W, Mayosi BM, Wilkinson RJ, Wilkinson KA
European journal of immunology 2012 Jan;42(1):147-57
European journal of immunology 2012 Jan;42(1):147-57
Humoral and cell-mediated immune responses to monovalent 2009 influenza A/H1N1 and seasonal trivalent influenza vaccines in high-risk children.
Long CB, Ramos I, Rastogi D, Manwani D, Janow G, Del Rio M, Mayers M, Herold BC, Fernandez-Sesma A, Madan RP
The Journal of pediatrics 2012 Jan;160(1):74-81
The Journal of pediatrics 2012 Jan;160(1):74-81
Human adenovirus-specific T cells modulate HIV-specific T cell responses to an Ad5-vectored HIV-1 vaccine.
Frahm N, DeCamp AC, Friedrich DP, Carter DK, Defawe OD, Kublin JG, Casimiro DR, Duerr A, Robertson MN, Buchbinder SP, Huang Y, Spies GA, De Rosa SC, McElrath MJ
The Journal of clinical investigation 2012 Jan;122(1):359-67
The Journal of clinical investigation 2012 Jan;122(1):359-67
Vaccine vectors derived from a large collection of simian adenoviruses induce potent cellular immunity across multiple species.
Colloca S, Barnes E, Folgori A, Ammendola V, Capone S, Cirillo A, Siani L, Naddeo M, Grazioli F, Esposito ML, Ambrosio M, Sparacino A, Bartiromo M, Meola A, Smith K, Kurioka A, O'Hara GA, Ewer KJ, Anagnostou N, Bliss C, Hill AV, Traboni C, Klenerman P, Cortese R, Nicosia A
Science translational medicine 2012 Jan 4;4(115):115ra2
Science translational medicine 2012 Jan 4;4(115):115ra2
Novel adenovirus-based vaccines induce broad and sustained T cell responses to HCV in man.
Barnes E, Folgori A, Capone S, Swadling L, Aston S, Kurioka A, Meyer J, Huddart R, Smith K, Townsend R, Brown A, Antrobus R, Ammendola V, Naddeo M, O'Hara G, Willberg C, Harrison A, Grazioli F, Esposito ML, Siani L, Traboni C, Oo Y, Adams D, Hill A, Colloca S, Nicosia A, Cortese R, Klenerman P
Science translational medicine 2012 Jan 4;4(115):115ra1
Science translational medicine 2012 Jan 4;4(115):115ra1
A new antigen scanning strategy for monitoring HIV-1 specific T-cell immune responses.
Malnati MS, Heltai S, Cosma A, Reitmeir P, Allgayer S, Glashoff RH, Liebrich W, Vardas E, Imami N, Westrop S, Nozza S, Tambussi G, Buttò S, Fanales-Belasio E, Ensoli B, Ensoli F, Tripiciano A, Fortis C, Lusso P, Poli G, Erfle V, Holmes H
Journal of immunological methods 2012 Jan 31;375(1-2):46-56
Journal of immunological methods 2012 Jan 31;375(1-2):46-56
High-avidity, high-IFNγ-producing CD8 T-cell responses following immune selection during HIV-1 infection.
Keane NM, Roberts SG, Almeida CA, Krishnan T, Chopra A, Demaine E, Laird R, Tschochner M, Carlson JM, Mallal S, Heckerman D, James I, John M
Immunology and cell biology 2012 Feb;90(2):224-34
Immunology and cell biology 2012 Feb;90(2):224-34
Characterization and comparison of 'standard' and 'young' tumour-infiltrating lymphocytes for adoptive cell therapy at a Danish translational research institution.
Donia M, Junker N, Ellebaek E, Andersen MH, Straten PT, Svane IM
Scandinavian journal of immunology 2012 Feb;75(2):157-67
Scandinavian journal of immunology 2012 Feb;75(2):157-67
Developing a new clinical tool for diagnosing chronic Q fever: the Coxiella ELISPOT.
Limonard GJ, Thijsen SF, Bossink AW, Asscheman A, Bouwman JJ
FEMS immunology and medical microbiology 2012 Feb;64(1):57-60
FEMS immunology and medical microbiology 2012 Feb;64(1):57-60
T-cell therapy for EBV-associated nasopharyngeal carcinoma: preparative lymphodepleting chemotherapy does not improve clinical results.
Secondino S, Zecca M, Licitra L, Gurrado A, Schiavetto I, Bossi P, Locati L, Schiavo R, Basso S, Baldanti F, Maccario R, Locatelli F, Siena S, Pedrazzoli P, Comoli P
Annals of oncology : official journal of the European Society for Medical Oncology 2012 Feb;23(2):435-41
Annals of oncology : official journal of the European Society for Medical Oncology 2012 Feb;23(2):435-41
Human endogenous retrovirus K(HML-2) Gag- and Env-specific T-cell responses are infrequently detected in HIV-1-infected subjects using standard peptide matrix-based screening.
Jones RB, John VM, Hunter DV, Martin E, Mujib S, Mihajlovic V, Burgers PC, Luider TM, Gyenes G, Sheppard NC, Sengupta D, Tandon R, Yue FY, Benko E, Kovacs C, Nixon DF, Ostrowski MA
Clinical and vaccine immunology : CVI 2012 Feb;19(2):288-92
Clinical and vaccine immunology : CVI 2012 Feb;19(2):288-92
Dynamics of cell-mediated immune responses to cytomegalovirus in pediatric transplantation recipients.
Patel M, Stefanidou M, Long CB, Fazzari MJ, Tesfa L, Del Rio M, Lamour J, Ricafort R, Madan RP, Herold BC
Pediatric transplantation 2012 Feb;16(1):18-28
Pediatric transplantation 2012 Feb;16(1):18-28
Modification of the carboxy-terminal flanking region of a universal influenza epitope alters CD4⁺ T-cell repertoire selection.
Cole DK, Gallagher K, Lemercier B, Holland CJ, Junaid S, Hindley JP, Wynn KK, Gostick E, Sewell AK, Gallimore AM, Ladell K, Price DA, Gougeon ML, Godkin A
Nature communications 2012 Feb 7;3:665
Nature communications 2012 Feb 7;3:665
Inclusion of a CRF01_AE HIV envelope protein boost with a DNA/MVA prime-boost vaccine: Impact on humoral and cellular immunogenicity and viral load reduction after SHIV-E challenge.
Cox JH, Ferrari MG, Earl P, Lane JR, Jagodzinski LL, Polonis VR, Kuta EG, Boyer JD, Ratto-Kim S, Eller LA, Pham DT, Hart L, Montefiori D, Ferrari G, Parrish S, Weiner DB, Moss B, Kim JH, Birx D, VanCott TC
Vaccine 2012 Feb 27;30(10):1830-40
Vaccine 2012 Feb 27;30(10):1830-40
IL-21 can supplement suboptimal Lck-independent MAPK activation in a STAT-3-dependent manner in human CD8(+) T cells.
Imataki O, Ansén S, Tanaka M, Butler MO, Berezovskaya A, Milstein MI, Kuzushima K, Nadler LM, Hirano N
Journal of immunology (Baltimore, Md. : 1950) 2012 Feb 15;188(4):1609-19
Journal of immunology (Baltimore, Md. : 1950) 2012 Feb 15;188(4):1609-19
Phase 1 clinical trial of HER2-specific immunotherapy with concomitant HER2 kinase inhibition [corrected].
Hamilton E, Blackwell K, Hobeika AC, Clay TM, Broadwater G, Ren XR, Chen W, Castro H, Lehmann F, Spector N, Wei J, Osada T, Lyerly HK, Morse MA
Journal of translational medicine 2012 Feb 10;10:28
Journal of translational medicine 2012 Feb 10;10:28
Immunological status in patients undergoing in vitro fertilisation: responses to hormone treatment and relationship to outcome.
Persson M, Ekerfelt C, Jablonowska B, Jonsson Y, Ernerudh J, Jenmalm MC, Berg G
Journal of reproductive immunology 2012 Dec;96(1-2):58-67
Journal of reproductive immunology 2012 Dec;96(1-2):58-67
Induction of MAGE-A3 and HPV-16 immunity by Trojan vaccines in patients with head and neck carcinoma.
Voskens CJ, Sewell D, Hertzano R, DeSanto J, Rollins S, Lee M, Taylor R, Wolf J, Suntharalingam M, Gastman B, Papadimitriou JC, Lu C, Tan M, Morales R, Cullen K, Celis E, Mann D, Strome SE
Head & neck 2012 Dec;34(12):1734-46
Head & neck 2012 Dec;34(12):1734-46
The high frequency of HIV type 1-specific cellular immune responses in seronegative individuals with parenteral and/or heterosexual HIV type 1 exposure.
Murashev BV, Nazarenko OV, Akulova EB, Artemyeva AK, Verevochkin SV, Shaboltas AV, Skochilov RV, Toussova OV, Kozlov AP
AIDS research and human retroviruses 2012 Dec;28(12):1598-605
AIDS research and human retroviruses 2012 Dec;28(12):1598-605
α-type-1 polarized dendritic cell-based vaccination in recurrent high-grade glioma: a phase I clinical trial.
Akiyama Y, Oshita C, Kume A, Iizuka A, Miyata H, Komiyama M, Ashizawa T, Yagoto M, Abe Y, Mitsuya K, Watanabe R, Sugino T, Yamaguchi K, Nakasu Y
BMC cancer 2012 Dec 27;12:623
BMC cancer 2012 Dec 27;12:623
Conservation of HIV-1 T cell epitopes across time and clades: validation of immunogenic HLA-A2 epitopes selected for the GAIA HIV vaccine.
Levitz L, Koita OA, Sangare K, Ardito MT, Boyle CM, Rozehnal J, Tounkara K, Dao SM, Koné Y, Koty Z, Buus S, Moise L, Martin WD, De Groot AS
Vaccine 2012 Dec 14;30(52):7547-60
Vaccine 2012 Dec 14;30(52):7547-60
Limited induction of tumor cross-reactive T cells without a measurable clinical benefit in early melanoma patients vaccinated with human leukocyte antigen class I-modified peptides.
Filipazzi P, Pilla L, Mariani L, Patuzzo R, Castelli C, Camisaschi C, Maurichi A, Cova A, Rigamonti G, Giardino F, Di Florio A, Asioli M, Frati P, Sovena G, Squarcina P, Maio M, Danielli R, Chiarion-Sileni V, Villa A, Lombardo C, Tragni G, Santinami M, Parmiani G, Rivoltini L
Clinical cancer research : an official journal of the American Association for Cancer Research 2012 Dec 1;18(23):6485-96
Clinical cancer research : an official journal of the American Association for Cancer Research 2012 Dec 1;18(23):6485-96
Endometrial receptivity defects and impaired implantation in diabetic NOD mice.
Albaghdadi AJ, Kan FW
Biology of reproduction 2012 Aug;87(2):30
Biology of reproduction 2012 Aug;87(2):30
Ex vivo enrichment of circulating anti-tumor T cells from both cutaneous and ocular melanoma patients: clinical implications for adoptive cell transfer therapy.
Mazzarella T, Cambiaghi V, Rizzo N, Pilla L, Parolini D, Orsenigo E, Colucci A, Modorati G, Doglioni C, Parmiani G, Maccalli C
Cancer immunology, immunotherapy : CII 2012 Aug;61(8):1169-82
Cancer immunology, immunotherapy : CII 2012 Aug;61(8):1169-82
Suppression of tumour-specific CD4⁺ T cells by regulatory T cells is associated with progression of human colorectal cancer.
Betts G, Jones E, Junaid S, El-Shanawany T, Scurr M, Mizen P, Kumar M, Jones S, Rees B, Williams G, Gallimore A, Godkin A
Gut 2012 Aug;61(8):1163-71
Gut 2012 Aug;61(8):1163-71
Generating CTLs against the subdominant EBV LMP antigens by transient expression of an A20 inhibitor with EBV LMP proteins in human DCs.
Hong B, Peng G, Berry L, Gottschalk S, Jung JU, Chen SY, Huang XF
Gene therapy 2012 Aug;19(8):818-27
Gene therapy 2012 Aug;19(8):818-27
Short wheat challenge is a reproducible in-vivo assay to detect immune response to gluten.
Camarca A, Radano G, Di Mase R, Terrone G, Maurano F, Auricchio S, Troncone R, Greco L, Gianfrani C
Clinical and experimental immunology 2012 Aug;169(2):129-36
Clinical and experimental immunology 2012 Aug;169(2):129-36
Adoptive cell therapy with autologous tumor infiltrating lymphocytes and low-dose Interleukin-2 in metastatic melanoma patients.
Ellebaek E, Iversen TZ, Junker N, Donia M, Engell-Noerregaard L, Met Ö, Hölmich LR, Andersen RS, Hadrup SR, Andersen MH, thor Straten P, Svane IM
Journal of translational medicine 2012 Aug 21;10:169
Journal of translational medicine 2012 Aug 21;10:169
T cell responses to known allergen proteins are differently polarized and account for a variable fraction of total response to allergen extracts.
Oseroff C, Sidney J, Vita R, Tripple V, McKinney DM, Southwood S, Brodie TM, Sallusto F, Grey H, Alam R, Broide D, Greenbaum JA, Kolla R, Peters B, Sette A
Journal of immunology (Baltimore, Md. : 1950) 2012 Aug 15;189(4):1800-11
Journal of immunology (Baltimore, Md. : 1950) 2012 Aug 15;189(4):1800-11
Doxycycline-mediated effects on persistent symptoms and systemic cytokine responses post-neuroborreliosis: a randomized, prospective, cross-over study.
Sjöwall J, Ledel A, Ernerudh J, Ekerfelt C, Forsberg P
BMC infectious diseases 2012 Aug 10;12:186
BMC infectious diseases 2012 Aug 10;12:186
Widespread CD4+ T-cell reactivity to novel hTERT epitopes following vaccination of cancer patients with a single hTERT peptide GV1001.
Inderberg-Suso EM, Trachsel S, Lislerud K, Rasmussen AM, Gaudernack G
Oncoimmunology 2012 Aug 1;1(5):670-686
Oncoimmunology 2012 Aug 1;1(5):670-686
Identification of an immunodominant region of the major house dust mite allergen Der p 2 presented by common human leucocyte antigen alleles.
Crack LR, Chan HW, McPherson T, Ogg GS
Clinical and experimental dermatology 2012 Apr;37(3):266-76
Clinical and experimental dermatology 2012 Apr;37(3):266-76
Changes in the levels of cytokines, chemokines and malaria-specific antibodies in response to Plasmodium falciparum infection in children living in sympatry in Mali.
Boström S, Giusti P, Arama C, Persson JO, Dara V, Traore B, Dolo A, Doumbo O, Troye-Blomberg M
Malaria journal 2012 Apr 5;11:109
Malaria journal 2012 Apr 5;11:109
Phase I randomised clinical trial of an HIV-1(CN54), clade C, trimeric envelope vaccine candidate delivered vaginally.
Lewis DJ, Fraser CA, Mahmoud AN, Wiggins RC, Woodrow M, Cope A, Cai C, Giemza R, Jeffs SA, Manoussaka M, Cole T, Cranage MP, Shattock RJ, Lacey CJ
PloS one 2011;6(9):e25165
PloS one 2011;6(9):e25165
A novel immunodominant CD8+ T cell response restricted by a common HLA-C allele targets a conserved region of Gag HIV-1 clade CRF01_AE infected Thais.
Buranapraditkun S, Hempel U, Pitakpolrat P, Allgaier RL, Thantivorasit P, Lorenzen SI, Sirivichayakul S, Hildebrand WH, Altfeld M, Brander C, Walker BD, Phanuphak P, Hansasuta P, Rowland-Jones SL, Allen TM, Ruxrungtham K
PloS one 2011;6(8):e23603
PloS one 2011;6(8):e23603
Unique CRF01_AE Gag CTL epitopes associated with lower HIV-viral load and delayed disease progression in a cohort of HIV-infected Thais.
Mori M, Sriwanthana B, Wichukchinda N, Boonthimat C, Tsuchiya N, Miura T, Pathipvanich P, Ariyoshi K, Sawanpanyalert P
PloS one 2011;6(8):e22680
PloS one 2011;6(8):e22680
A molecular assay for sensitive detection of pathogen-specific T-cells.
Kasprowicz VO, Mitchell JE, Chetty S, Govender P, Huang KH, Fletcher HA, Webster DP, Brown S, Kasmar A, Millington K, Day CL, Mkhwanazi N, McClurg C, Chonco F, Lalvani A, Walker BD, Ndung'u T, Klenerman P
PloS one 2011;6(8):e20606
PloS one 2011;6(8):e20606
Vaccination against heterologous R5 clade C SHIV: prevention of infection and correlates of protection.
Lakhashe SK, Wang W, Siddappa NB, Hemashettar G, Polacino P, Hu SL, Villinger F, Else JG, Novembre FJ, Yoon JK, Lee SJ, Montefiori DC, Ruprecht RM, Rasmussen RA
PloS one 2011;6(7):e22010
PloS one 2011;6(7):e22010
Immunodominance of HIV-1 specific CD8+ T-cell responses is related to disease progression rate in vertically infected adolescents.
Sharp ER, Willberg CB, Kuebler PJ, Abadi J, Fennelly GJ, Dobroszycki J, Wiznia AA, Rosenberg MG, Nixon DF
PloS one 2011;6(7):e21135
PloS one 2011;6(7):e21135
Day-4 myeloid dendritic cells pulsed with whole tumor lysate are highly immunogenic and elicit potent anti-tumor responses.
Chiang CL, Hagemann AR, Leskowitz R, Mick R, Garrabrant T, Czerniecki BJ, Kandalaft LE, Powell DJ Jr, Coukos G
PloS one 2011;6(12):e28732
PloS one 2011;6(12):e28732
Evaluation of approaches to identify the targets of cellular immunity on a proteome-wide scale.
Cardoso FC, Roddick JS, Groves P, Doolan DL
PloS one 2011;6(11):e27666
PloS one 2011;6(11):e27666
An MSI tumor specific frameshift mutation in a coding microsatellite of MSH3 encodes for HLA-A0201-restricted CD8+ cytotoxic T cell epitopes.
Garbe Y, Maletzki C, Linnebacher M
PloS one 2011;6(11):e26517
PloS one 2011;6(11):e26517
Identification of antigens specific to non-tuberculous mycobacteria: the Mce family of proteins as a target of T cell immune responses.
Checkley AM, Wyllie DH, Scriba TJ, Golubchik T, Hill AV, Hanekom WA, McShane H
PloS one 2011;6(10):e26434
PloS one 2011;6(10):e26434
Intra- and inter-clade cross-reactivity by HIV-1 Gag specific T-cells reveals exclusive and commonly targeted regions: implications for current vaccine trials.
Zembe L, Burgers WA, Jaspan HB, Bekker LG, Bredell H, Stevens G, Gilmour J, Cox JH, Fast P, Hayes P, Vardas E, Williamson C, Gray CM
PloS one 2011;6(10):e26096
PloS one 2011;6(10):e26096
Circumsporozoite-specific T cell responses in children vaccinated with RTS,S/AS01E and protection against P falciparum clinical malaria.
Olotu A, Moris P, Mwacharo J, Vekemans J, Kimani D, Janssens M, Kai O, Jongert E, Lievens M, Leach A, Villafana T, Savarese B, Marsh K, Cohen J, Bejon P
PloS one 2011;6(10):e25786
PloS one 2011;6(10):e25786
Direct ex-vivo evaluation of pneumococcal specific T-cells in healthy adults.
Aslam A, Chapel H, Ogg G
PloS one 2011;6(10):e25367
PloS one 2011;6(10):e25367
EBV-gp350 confers B-cell tropism to tailored exosomes and is a neo-antigen in normal and malignant B cells--a new option for the treatment of B-CLL.
Ruiss R, Jochum S, Mocikat R, Hammerschmidt W, Zeidler R
PloS one 2011;6(10):e25294
PloS one 2011;6(10):e25294
Evidence of hepatitis E virus exposure among seronegative healthy residents of an endemic area.
Husain MM, Srivastava R, Akondy R, Aggarwal R, Jameel S, Naik S
Intervirology 2011;54(3):139-43
Intervirology 2011;54(3):139-43
Immunosenescent CD57+CD4+ T-cells accumulate and contribute to interferon-γ responses in HIV patients responding stably to ART.
Fernandez S, French MA, Price P
Disease markers 2011;31(6):337-42
Disease markers 2011;31(6):337-42
Characterization of ex vivo expanded tumor infiltrating lymphocytes from patients with malignant melanoma for clinical application.
Junker N, Thor Straten P, Andersen MH, Svane IM
Journal of skin cancer 2011;2011:574695
Journal of skin cancer 2011;2011:574695
Safety and Immunogenicity of a Human Papillomavirus Peptide Vaccine (CIGB-228) in Women with High-Grade Cervical Intraepithelial Neoplasia: First-in-Human, Proof-of-Concept Trial.
Solares AM, Baladron I, Ramos T, Valenzuela C, Borbon Z, Fanjull S, Gonzalez L, Castillo D, Esmir J, Granadillo M, Batte A, Cintado A, Ale M, Fernandez de Cossio ME, Ferrer A, Torrens I, Lopez-Saura P
ISRN obstetrics and gynecology 2011;2011:292951
ISRN obstetrics and gynecology 2011;2011:292951
Standardized Serum-Free Cryomedia Maintain Peripheral Blood Mononuclear Cell Viability, Recovery, and Antigen-Specific T-Cell Response Compared to Fetal Calf Serum-Based Medium.
Germann A, Schulz JC, Kemp-Kamke B, Zimmermann H, von Briesen H
Biopreservation and biobanking 2011 Sep;9(3):229-236
Biopreservation and biobanking 2011 Sep;9(3):229-236
Phase I (safety) study of autologous tolerogenic dendritic cells in type 1 diabetic patients.
Giannoukakis N, Phillips B, Finegold D, Harnaha J, Trucco M
Diabetes care 2011 Sep;34(9):2026-32
Diabetes care 2011 Sep;34(9):2026-32
Immunological effects of low-dose cyclophosphamide in cancer patients treated with oncolytic adenovirus.
Cerullo V, Diaconu I, Kangasniemi L, Rajecki M, Escutenaire S, Koski A, Romano V, Rouvinen N, Tuuminen T, Laasonen L, Partanen K, Kauppinen S, Joensuu T, Oksanen M, Holm SL, Haavisto E, Karioja-Kallio A, Kanerva A, Pesonen S, Arstila PT, Hemminki A
Molecular therapy : the journal of the American Society of Gene Therapy 2011 Sep;19(9):1737-46
Molecular therapy : the journal of the American Society of Gene Therapy 2011 Sep;19(9):1737-46
Antigen-specific T cell responses to BK polyomavirus antigens identify functional anti-viral immunity and may help to guide immunosuppression following renal transplantation.
Chakera A, Bennett S, Lawrence S, Morteau O, Mason PD, O'Callaghan CA, Cornall RJ
Clinical and experimental immunology 2011 Sep;165(3):401-9
Clinical and experimental immunology 2011 Sep;165(3):401-9
A poxvirus vaccine is safe, induces T-cell responses, and decreases viral load in patients with chronic hepatitis C.
Habersetzer F, Honnet G, Bain C, Maynard-Muet M, Leroy V, Zarski JP, Feray C, Baumert TF, Bronowicki JP, Doffoël M, Trépo C, Agathon D, Toh ML, Baudin M, Bonnefoy JY, Limacher JM, Inchauspé G
Gastroenterology 2011 Sep;141(3):890-899.e1-4
Gastroenterology 2011 Sep;141(3):890-899.e1-4
Effect of oxygen levels on the physiology of dendritic cells: implications for adoptive cell therapy.
Futalan D, Huang CT, Schmidt-Wolf IG, Larsson M, Messmer D
Molecular medicine (Cambridge, Mass.) 2011 Sep-Oct;17(9-10):910-6
Molecular medicine (Cambridge, Mass.) 2011 Sep-Oct;17(9-10):910-6
Semiallogenic fusions of MSI(+) tumor cells and activated B cells induce MSI-specific T cell responses.
Garbe Y, Klier U, Linnebacher M
BMC cancer 2011 Sep 26;11:410
BMC cancer 2011 Sep 26;11:410
Development of an interferon-gamma ELISPOT assay to detect human T cell responses to HSV-2.
Posavad CM, Magaret AS, Zhao L, Mueller DE, Wald A, Corey L
Vaccine 2011 Sep 16;29(40):7058-66
Vaccine 2011 Sep 16;29(40):7058-66
Functional gap junctions accumulate at the immunological synapse and contribute to T cell activation.
Mendoza-Naranjo A, Bouma G, Pereda C, Ramírez M, Webb KF, Tittarelli A, López MN, Kalergis AM, Thrasher AJ, Becker DL, Salazar-Onfray F
Journal of immunology (Baltimore, Md. : 1950) 2011 Sep 15;187(6):3121-32
Journal of immunology (Baltimore, Md. : 1950) 2011 Sep 15;187(6):3121-32
Augmented HIV-specific interferon-gamma responses, but impaired lymphoproliferation during interruption of antiretroviral treatment initiated in primary HIV infection.
Connick E, Bosch RJ, Aga E, Schlichtemeier R, Demeter LM, Volberding P, ACTG 709 Team
Journal of acquired immune deficiency syndromes (1999) 2011 Sep 1;58(1):1-8
Journal of acquired immune deficiency syndromes (1999) 2011 Sep 1;58(1):1-8
Limited immunogenicity of HIV CD8+ T-cell epitopes in acute Clade C virus infection.
Radebe M, Nair K, Chonco F, Bishop K, Wright JK, van der Stok M, Bassett IV, Mncube Z, Altfeld M, Walker BD, Ndung'u T
The Journal of infectious diseases 2011 Sep 1;204(5):768-76
The Journal of infectious diseases 2011 Sep 1;204(5):768-76
Translation of HLA-HIV associations to the cellular level: HIV adapts to inflate CD8 T cell responses against Nef and HLA-adapted variant epitopes.
Almeida CA, Bronke C, Roberts SG, McKinnon E, Keane NM, Chopra A, Kadie C, Carlson J, Haas DW, Riddler SA, Haubrich R, Heckerman D, Mallal S, John M
Journal of immunology (Baltimore, Md. : 1950) 2011 Sep 1;187(5):2502-13
Journal of immunology (Baltimore, Md. : 1950) 2011 Sep 1;187(5):2502-13
Differences in Kaposi sarcoma-associated herpesvirus-specific and herpesvirus-non-specific immune responses in classic Kaposi sarcoma cases and matched controls in Sicily.
Amodio E, Goedert JJ, Barozzi P, Riva G, Firenze A, Bonura F, Viviano E, Romano N, Luppi M
Cancer science 2011 Oct;102(10):1769-73
Cancer science 2011 Oct;102(10):1769-73
A human Phase I/IIa malaria challenge trial of a polyprotein malaria vaccine.
Porter DW, Thompson FM, Berthoud TK, Hutchings CL, Andrews L, Biswas S, Poulton I, Prieur E, Correa S, Rowland R, Lang T, Williams J, Gilbert SC, Sinden RE, Todryk S, Hill AV
Vaccine 2011 Oct 6;29(43):7514-22
Vaccine 2011 Oct 6;29(43):7514-22
Broad and potent immune responses to a low dose intradermal HIV-1 DNA boosted with HIV-1 recombinant MVA among healthy adults in Tanzania.
Bakari M, Aboud S, Nilsson C, Francis J, Buma D, Moshiro C, Aris EA, Lyamuya EF, Janabi M, Godoy-Ramirez K, Joachim A, Polonis VR, Bråve A, Earl P, Robb M, Marovich M, Wahren B, Pallangyo K, Biberfeld G, Mhalu F, Sandström E
Vaccine 2011 Oct 26;29(46):8417-28
Vaccine 2011 Oct 26;29(46):8417-28
Virus aggregating peptide enhances the cell-mediated response to influenza virus vaccine.
Jones JC, Settles EW, Brandt CR, Schultz-Cherry S
Vaccine 2011 Oct 13;29(44):7696-703
Vaccine 2011 Oct 13;29(44):7696-703
Cell-mediated immune responses to inactivated trivalent influenza-vaccination are decreased in patients with common variable immunodeficiency.
van Assen S, de Haan A, Holvast A, Horst G, Gorter L, Westra J, Kallenberg CG, Telgt DS, Palache AM, Giezeman KM, Bijl M
Clinical immunology (Orlando, Fla.) 2011 Nov;141(2):161-8
Clinical immunology (Orlando, Fla.) 2011 Nov;141(2):161-8
Immunization with the RTS,S/AS malaria vaccine induces IFN-γ(+)CD4 T cells that recognize only discrete regions of the circumsporozoite protein and these specificities are maintained following booster immunizations and challenge.
Schwenk R, Lumsden JM, Rein LE, Juompan L, Kester KE, Heppner DG, Krzych U
Vaccine 2011 Nov 8;29(48):8847-54
Vaccine 2011 Nov 8;29(48):8847-54
Age-related changes in durability and function of vaccine-elicited influenza-specific CD4(+) T-cell responses.
Mahnke YD, Saqr A, Hazenfeld S, Brady RC, Roederer M, Subbramanian RA
Vaccine 2011 Nov 3;29(47):8606-14
Vaccine 2011 Nov 3;29(47):8606-14
Merkel cell polyomavirus-specific CD8⁺ and CD4⁺ T-cell responses identified in Merkel cell carcinomas and blood.
Iyer JG, Afanasiev OK, McClurkan C, Paulson K, Nagase K, Jing L, Marshak JO, Dong L, Carter J, Lai I, Farrar E, Byrd D, Galloway D, Yee C, Koelle DM, Nghiem P
Clinical cancer research : an official journal of the American Association for Cancer Research 2011 Nov 1;17(21):6671-80
Clinical cancer research : an official journal of the American Association for Cancer Research 2011 Nov 1;17(21):6671-80
Distinguishing between the innate immune response due to ocular inflammation and infection in a child with juvenile systemic granulomatous disease treated with anti-TNFα monoclonal antibodies.
Sharma SM, Martin TM, Rosé CD, Dick AD, Ramanan AV
Rheumatology (Oxford, England) 2011 May;50(5):990-2
Rheumatology (Oxford, England) 2011 May;50(5):990-2
Hypercytokinaemia accompanies HIV-tuberculosis immune reconstitution inflammatory syndrome.
Tadokera R, Meintjes G, Skolimowska KH, Wilkinson KA, Matthews K, Seldon R, Chegou NN, Maartens G, Rangaka MX, Rebe K, Walzl G, Wilkinson RJ
The European respiratory journal 2011 May;37(5):1248-59
The European respiratory journal 2011 May;37(5):1248-59
Identification of T cell epitopes on soluble liver antigen in Chinese patients with auto-immune hepatitis.
Zhao Y, Zhang Y, Liu YM, Liu Y, Feng X, Liao HY, Vergani D, Ma Y, Yan HP
Liver international : official journal of the International Association for the Study of the Liver 2011 May;31(5):721-9
Liver international : official journal of the International Association for the Study of the Liver 2011 May;31(5):721-9
CD200 expression suppresses natural killer cell function and directly inhibits patient anti-tumor response in acute myeloid leukemia.
Coles SJ, Wang EC, Man S, Hills RK, Burnett AK, Tonks A, Darley RL
Leukemia 2011 May;25(5):792-9
Leukemia 2011 May;25(5):792-9
The clinical value of concomitant Epstein Barr virus (EBV)-DNA load and specific immune reconstitution monitoring after allogeneic hematopoietic stem cell transplantation.
D'Aveni M, Aïssi-Rothé L, Venard V, Salmon A, Falenga A, Decot V, Virion JM, Wang Y, Clement L, Latger-Cannard V, Tomowiak C, Stoltz JF, Bordigoni P, Bensoussan D
Transplant immunology 2011 May;24(4):224-32
Transplant immunology 2011 May;24(4):224-32
IFN-α boosts epitope cross-presentation by dendritic cells via modulation of proteasome activity.
Lattanzi L, Rozera C, Marescotti D, D'Agostino G, Santodonato L, Cellini S, Belardelli F, Gavioli R, Ferrantini M
Immunobiology 2011 May;216(5):537-47
Immunobiology 2011 May;216(5):537-47
The polyomavirus BK large T-antigen-derived peptide elicits an HLA-DR promiscuous and polyfunctional CD4+ T-cell response.
Ramaswami B, Popescu I, Macedo C, Luo C, Shapiro R, Metes D, Chalasani G, Randhawa PS
Clinical and vaccine immunology : CVI 2011 May;18(5):815-24
Clinical and vaccine immunology : CVI 2011 May;18(5):815-24
Systematic identification of immunodominant CD8+ T-cell responses to influenza A virus in HLA-A2 individuals.
Wu C, Zanker D, Valkenburg S, Tan B, Kedzierska K, Zou QM, Doherty PC, Chen W
Proceedings of the National Academy of Sciences of the United States of America 2011 May 31;108(22):9178-83
Proceedings of the National Academy of Sciences of the United States of America 2011 May 31;108(22):9178-83
Th17/Th1 biased immunity to the pneumococcal proteins PcsB, StkP and PsaA in adults of different age.
Schmid P, Selak S, Keller M, Luhan B, Magyarics Z, Seidel S, Schlick P, Reinisch C, Lingnau K, Nagy E, Grubeck-Loebenstein B
Vaccine 2011 May 23;29(23):3982-9
Vaccine 2011 May 23;29(23):3982-9
EBV-specific CD8+ T cells from asymptomatic pediatric thoracic transplant patients carrying chronic high EBV loads display contrasting features: activated phenotype and exhausted function.
Macedo C, Webber SA, Donnenberg AD, Popescu I, Hua Y, Green M, Rowe D, Smith L, Brooks MM, Metes D
Journal of immunology (Baltimore, Md. : 1950) 2011 May 15;186(10):5854-62
Journal of immunology (Baltimore, Md. : 1950) 2011 May 15;186(10):5854-62
Natural killer cells from children with type 1 diabetes have defects in NKG2D-dependent function and signaling.
Qin H, Lee IF, Panagiotopoulos C, Wang X, Chu AD, Utz PJ, Priatel JJ, Tan R
Diabetes 2011 Mar;60(3):857-66
Diabetes 2011 Mar;60(3):857-66
Cotransfection of Poly(I: C) and siRNA of IL-10 into fusions of dendritic and glioma cells enhances antitumor T helper type 1 induction in patients with glioma.
Akasaki Y, Kikuchi T, Irie M, Yamamoto Y, Arai T, Tanaka T, Joki T, Abe T
Journal of immunotherapy (Hagerstown, Md. : 1997) 2011 Mar;34(2):121-8
Journal of immunotherapy (Hagerstown, Md. : 1997) 2011 Mar;34(2):121-8
Cytokine expression in tumors treated with donor lymphocyte infusions after allogeneic hematopoietic stem cell transplantation.
Conrad R, Remberger M, Cederlund K, Barkholt L
Immunotherapy 2011 Mar;3(3):443-51
Immunotherapy 2011 Mar;3(3):443-51
FLT3-regulated antigens as targets for leukemia-reactive cytotoxic T lymphocytes.
Brackertz B, Conrad H, Daniel J, Kast B, Krönig H, Busch DH, Adamski J, Peschel C, Bernhard H
Blood cancer journal 2011 Mar;1(3):e11
Blood cancer journal 2011 Mar;1(3):e11
Effect of hookworm infection on wheat challenge in celiac disease--a randomised double-blinded placebo controlled trial.
Daveson AJ, Jones DM, Gaze S, McSorley H, Clouston A, Pascoe A, Cooke S, Speare R, Macdonald GA, Anderson R, McCarthy JS, Loukas A, Croese J
PloS one 2011 Mar 8;6(3):e17366
PloS one 2011 Mar 8;6(3):e17366
Interethnic differences in antigen-presenting cell activation and TLR responses in Malian children during Plasmodium falciparum malaria.
Arama C, Giusti P, Boström S, Dara V, Traore B, Dolo A, Doumbo O, Varani S, Troye-Blomberg M
PloS one 2011 Mar 31;6(3):e18319
PloS one 2011 Mar 31;6(3):e18319
Decreased Th1-type inflammatory cytokine expression in the skin is associated with persisting symptoms after treatment of erythema migrans.
Sjöwall J, Fryland L, Nordberg M, Sjögren F, Garpmo U, Jansson C, Carlsson SA, Bergström S, Ernerudh J, Nyman D, Forsberg P, Ekerfelt C
PloS one 2011 Mar 31;6(3):e18220
PloS one 2011 Mar 31;6(3):e18220
CD8+ T cell immunity to 2009 pandemic and seasonal H1N1 influenza viruses.
Scheible K, Zhang G, Baer J, Azadniv M, Lambert K, Pryhuber G, Treanor JJ, Topham DJ
Vaccine 2011 Mar 3;29(11):2159-68
Vaccine 2011 Mar 3;29(11):2159-68
Ag85B-ESAT-6 adjuvanted with IC31® promotes strong and long-lived Mycobacterium tuberculosis specific T cell responses in volunteers with previous BCG vaccination or tuberculosis infection.
van Dissel JT, Soonawala D, Joosten SA, Prins C, Arend SM, Bang P, Tingskov PN, Lingnau K, Nouta J, Hoff ST, Rosenkrands I, Kromann I, Ottenhoff TH, Doherty TM, Andersen P
Vaccine 2011 Mar 3;29(11):2100-9
Vaccine 2011 Mar 3;29(11):2100-9
Specific recognition and inhibition of Ewing tumour growth by antigen-specific allo-restricted cytotoxic T cells.
Thiel U, Pirson S, Müller-Spahn C, Conrad H, Busch DH, Bernhard H, Burdach S, Richter GH
British journal of cancer 2011 Mar 15;104(6):948-56
British journal of cancer 2011 Mar 15;104(6):948-56
Intratumor T helper type 2 cell infiltrate correlates with cancer-associated fibroblast thymic stromal lymphopoietin production and reduced survival in pancreatic cancer.
De Monte L, Reni M, Tassi E, Clavenna D, Papa I, Recalde H, Braga M, Di Carlo V, Doglioni C, Protti MP
The Journal of experimental medicine 2011 Mar 14;208(3):469-78
The Journal of experimental medicine 2011 Mar 14;208(3):469-78
Comparison of antibody and T-cell responses elicited by licensed inactivated- and live-attenuated influenza vaccines against H3N2 hemagglutinin.
Basha S, Hazenfeld S, Brady RC, Subbramanian RA
Human immunology 2011 Jun;72(6):463-9
Human immunology 2011 Jun;72(6):463-9
Impaired tumor antigen processing by immunoproteasome-expressing CD40-activated B cells and dendritic cells.
Anderson KS, Zeng W, Sasada T, Choi J, Riemer AB, Su M, Drakoulakos D, Kang YJ, Brusic V, Wu C, Reinherz EL
Cancer immunology, immunotherapy : CII 2011 Jun;60(6):857-67
Cancer immunology, immunotherapy : CII 2011 Jun;60(6):857-67
Interferon-γ and proliferation responses to Salmonella enterica Serotype Typhi proteins in patients with S. Typhi Bacteremia in Dhaka, Bangladesh.
Sheikh A, Khanam F, Sayeed MA, Rahman T, Pacek M, Hu Y, Rollins A, Bhuiyan MS, Rollins S, Kalsy A, Arifuzzaman M, Leung DT, Sarracino DA, Krastins B, Charles RC, Larocque RC, Cravioto A, Calderwood SB, Brooks WA, Harris JB, Labaer J, Qadri F, Ryan ET
PLoS neglected tropical diseases 2011 Jun;5(6):e1193
PLoS neglected tropical diseases 2011 Jun;5(6):e1193
Quantitative analysis of the CD4 T-cell repertoire specific to therapeutic antibodies in healthy donors.
Delluc S, Ravot G, Maillere B
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2011 Jun;25(6):2040-8
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2011 Jun;25(6):2040-8
A mycolic acid-specific CD1-restricted T cell population contributes to acute and memory immune responses in human tuberculosis infection.
Montamat-Sicotte DJ, Millington KA, Willcox CR, Hingley-Wilson S, Hackforth S, Innes J, Kon OM, Lammas DA, Minnikin DE, Besra GS, Willcox BE, Lalvani A
The Journal of clinical investigation 2011 Jun;121(6):2493-503
The Journal of clinical investigation 2011 Jun;121(6):2493-503
Characterization of a branched lipopeptide candidate vaccine against influenza A/Puerto Rico 8/34 which is recognized by human B and T-cell immune responses.
Samayoa L, Diaz-Mitoma F, Azizi A
Virology journal 2011 Jun 16;8:309
Virology journal 2011 Jun 16;8:309
Human dendritic cell subsets from spleen and blood are similar in phenotype and function but modified by donor health status.
Mittag D, Proietto AI, Loudovaris T, Mannering SI, Vremec D, Shortman K, Wu L, Harrison LC
Journal of immunology (Baltimore, Md. : 1950) 2011 Jun 1;186(11):6207-17
Journal of immunology (Baltimore, Md. : 1950) 2011 Jun 1;186(11):6207-17
Strong human endogenous retrovirus-specific T cell responses are associated with control of HIV-1 in chronic infection.
SenGupta D, Tandon R, Vieira RG, Ndhlovu LC, Lown-Hecht R, Ormsby CE, Loh L, Jones RB, Garrison KE, Martin JN, York VA, Spotts G, Reyes-Terán G, Ostrowski MA, Hecht FM, Deeks SG, Nixon DF
Journal of virology 2011 Jul;85(14):6977-85
Journal of virology 2011 Jul;85(14):6977-85
Identification of Hydroxysteroid (17β) dehydrogenase type 12 (HSD17B12) as a CD8+ T-cell-defined human tumor antigen of human carcinomas.
Visus C, Ito D, Dhir R, Szczepanski MJ, Chang YJ, Latimer JJ, Grant SG, DeLeo AB
Cancer immunology, immunotherapy : CII 2011 Jul;60(7):919-29
Cancer immunology, immunotherapy : CII 2011 Jul;60(7):919-29
Decreased IFNγ production correlates with diminished production of cytokines by dendritic cells in patients infected with hepatitis C virus and receiving therapy.
Hammond T, Lee S, Watson MW, Flexman JP, Cheng W, Price P
Journal of viral hepatitis 2011 Jul;18(7):482-92
Journal of viral hepatitis 2011 Jul;18(7):482-92
The reconstitution of the thymus in immunosuppressed individuals restores CD4-specific cellular and humoral immune responses.
Plana M, Garcia F, Darwich L, Romeu J, López A, Cabrera C, Massanella M, Canto E, Ruiz-Hernandez R, Blanco J, Sánchez M, Gatell JM, Clotet B, Ruiz L, Bofill M, Red de Investigación en Sida (RIS)
Immunology 2011 Jul;133(3):318-28
Immunology 2011 Jul;133(3):318-28
Preparation, characterisation and entrapment of a non-glycosidic threitol ceramide into liposomes for presentation to invariant natural killer T cells.
Kaur R, Chen J, Dawoodji A, Cerundolo V, Garcia-Diaz YR, Wojno J, Cox LR, Besra GS, Moghaddam B, Perrie Y
Journal of pharmaceutical sciences 2011 Jul;100(7):2724-33
Journal of pharmaceutical sciences 2011 Jul;100(7):2724-33
Phylogenetic analysis consistent with a clinical history of sexual transmission of HIV-1 from a single donor reveals transmission of highly distinct variants.
English S, Katzourakis A, Bonsall D, Flanagan P, Duda A, Fidler S, Weber J, McClure M, SPARTAC Trial Investigators, Phillips R, Frater J
Retrovirology 2011 Jul 7;8:54
Retrovirology 2011 Jul 7;8:54
Single-walled carbon nanotubes deliver peptide antigen into dendritic cells and enhance IgG responses to tumor-associated antigens.
Villa CH, Dao T, Ahearn I, Fehrenbacher N, Casey E, Rey DA, Korontsvit T, Zakhaleva V, Batt CA, Philips MR, Scheinberg DA
ACS nano 2011 Jul 26;5(7):5300-11
ACS nano 2011 Jul 26;5(7):5300-11
Amplified antigen-specific immune responses in HIV-1 infected individuals in a double blind DNA immunization and therapy interruption trial.
Gudmundsdotter L, Wahren B, Haller BK, Boberg A, Edbäck U, Bernasconi D, Buttò S, Gaines H, Imami N, Gotch F, Lori F, Lisziewicz J, Sandström E, Hejdeman B
Vaccine 2011 Jul 26;29(33):5558-66
Vaccine 2011 Jul 26;29(33):5558-66
Multilayered defense in HLA-B51-associated HIV viral control.
Zhang Y, Peng Y, Yan H, Xu K, Saito M, Wu H, Chen X, Ranasinghe S, Kuse N, Powell T, Zhao Y, Li W, Zhang X, Feng X, Li N, Leligdowicz A, Xu X, John M, Takiguchi M, McMichael A, Rowland-Jones S, Dong T
Journal of immunology (Baltimore, Md. : 1950) 2011 Jul 15;187(2):684-91
Journal of immunology (Baltimore, Md. : 1950) 2011 Jul 15;187(2):684-91
Lenalidomide enhances antigen-specific activity and decreases CD45RA expression of T cells from patients with multiple myeloma.
Neuber B, Herth I, Tolliver C, Schoenland S, Hegenbart U, Hose D, Witzens-Harig M, Ho AD, Goldschmidt H, Klein B, Hundemer M
Journal of immunology (Baltimore, Md. : 1950) 2011 Jul 15;187(2):1047-56
Journal of immunology (Baltimore, Md. : 1950) 2011 Jul 15;187(2):1047-56
Phase I study utilizing a novel antigen-presenting cell-targeted vaccine with Toll-like receptor stimulation to induce immunity to self-antigens in cancer patients.
Morse MA, Chapman R, Powderly J, Blackwell K, Keler T, Green J, Riggs R, He LZ, Ramakrishna V, Vitale L, Zhao B, Butler SA, Hobeika A, Osada T, Davis T, Clay T, Lyerly HK
Clinical cancer research : an official journal of the American Association for Cancer Research 2011 Jul 15;17(14):4844-53
Clinical cancer research : an official journal of the American Association for Cancer Research 2011 Jul 15;17(14):4844-53
Multidrug-resistance proteins are weak tumor associated antigens for colorectal carcinoma.
Mullins CS, Eisold S, Klar E, Linnebacher M
BMC immunology 2011 Jul 10;12:38
BMC immunology 2011 Jul 10;12:38
CD4-positive T-helper cell responses to the PASD1 protein in patients with diffuse large B-cell lymphoma.
Ait-Tahar K, Liggins AP, Collins GP, Campbell A, Barnardo M, Cabes M, Lawrie CH, Moir D, Hatton C, Banham AH, Pulford K
Haematologica 2011 Jan;96(1):78-86
Haematologica 2011 Jan;96(1):78-86
Synbiotics reduce allergen-induced T-helper 2 response and improve peak expiratory flow in allergic asthmatics.
van de Pol MA, Lutter R, Smids BS, Weersink EJ, van der Zee JS
Allergy 2011 Jan;66(1):39-47
Allergy 2011 Jan;66(1):39-47
Hepatitis C virus-specific CD8+ T cell frequencies are associated with the responses of pegylated interferon-α and ribavirin combination therapy in patients with chronic hepatitis C virus infection.
Tatsumi T, Takehara T, Miyagi T, Nakazuru S, Mita E, Kanto T, Hiramatsu N, Hayashi N
Hepatology research : the official journal of the Japan Society of Hepatology 2011 Jan;41(1):30-8
Hepatology research : the official journal of the Japan Society of Hepatology 2011 Jan;41(1):30-8
Phase I clinical trial of a novel peptide vaccine in combination with UFT/LV for metastatic colorectal cancer.
Okuno K, Sugiura F, Hida JI, Tokoro T, Ishimaru E, Sukegawa Y, Ueda K
Experimental and therapeutic medicine 2011 Jan;2(1):73-79
Experimental and therapeutic medicine 2011 Jan;2(1):73-79
High immunogenic potential of p53 mRNA-transfected dendritic cells in patients with primary breast cancer.
Met O, Balslev E, Flyger H, Svane IM
Breast cancer research and treatment 2011 Jan;125(2):395-406
Breast cancer research and treatment 2011 Jan;125(2):395-406
Antibody-targeted NY-ESO-1 to mannose receptor or DEC-205 in vitro elicits dual human CD8+ and CD4+ T cell responses with broad antigen specificity.
Tsuji T, Matsuzaki J, Kelly MP, Ramakrishna V, Vitale L, He LZ, Keler T, Odunsi K, Old LJ, Ritter G, Gnjatic S
Journal of immunology (Baltimore, Md. : 1950) 2011 Jan 15;186(2):1218-27
Journal of immunology (Baltimore, Md. : 1950) 2011 Jan 15;186(2):1218-27
A live attenuated Listeria monocytogenes vaccine vector expressing SIV Gag is safe and immunogenic in macaques and can be administered repeatedly.
Sciaranghella G, Lakhashe SK, Ayash-Rashkovsky M, Mirshahidi S, Siddappa NB, Novembre FJ, Velu V, Amara RR, Zhou C, Li S, Li Z, Frankel FR, Ruprecht RM
Vaccine 2011 Jan 10;29(3):476-86
Vaccine 2011 Jan 10;29(3):476-86
Biologic and immunologic effects of preoperative trastuzumab for ductal carcinoma in situ of the breast.
Kuerer HM, Buzdar AU, Mittendorf EA, Esteva FJ, Lucci A, Vence LM, Radvanyi L, Meric-Bernstam F, Hunt KK, Symmans WF
Cancer 2011 Jan 1;117(1):39-47
Cancer 2011 Jan 1;117(1):39-47
Immune responses and protection of Aotus monkeys immunized with irradiated Plasmodium vivax sporozoites.
Jordán-Villegas A, Perdomo AB, Epstein JE, López J, Castellanos A, Manzano MR, Hernández MA, Soto L, Méndez F, Richie TL, Hoffman SL, Arévalo-Herrera M, Herrera S
The American journal of tropical medicine and hygiene 2011 Feb;84(2 Suppl):43-50
The American journal of tropical medicine and hygiene 2011 Feb;84(2 Suppl):43-50
Antibody-mediated and cellular immune responses induced in naive volunteers by vaccination with long synthetic peptides derived from the Plasmodium vivax circumsporozoite protein.
Arévalo-Herrera M, Soto L, Perlaza BL, Céspedes N, Vera O, Lenis AM, Bonelo A, Corradin G, Herrera S
The American journal of tropical medicine and hygiene 2011 Feb;84(2 Suppl):35-42
The American journal of tropical medicine and hygiene 2011 Feb;84(2 Suppl):35-42
Phase I safety and immunogenicity trial of Plasmodium vivax CS derived long synthetic peptides adjuvanted with montanide ISA 720 or montanide ISA 51.
Herrera S, Fernández OL, Vera O, Cárdenas W, Ramírez O, Palacios R, Chen-Mok M, Corradin G, Arévalo-Herrera M
The American journal of tropical medicine and hygiene 2011 Feb;84(2 Suppl):12-20
The American journal of tropical medicine and hygiene 2011 Feb;84(2 Suppl):12-20
Identification of a cyclin B1-derived CTL epitope eliciting spontaneous responses in both cancer patients and healthy donors.
Andersen RS, Sørensen RB, Ritter C, Svane IM, Becker JC, thor Straten P, Andersen MH
Cancer immunology, immunotherapy : CII 2011 Feb;60(2):227-34
Cancer immunology, immunotherapy : CII 2011 Feb;60(2):227-34
Partially randomized, non-blinded trial of DNA and MVA therapeutic vaccines based on hepatitis B virus surface protein for chronic HBV infection.
Cavenaugh JS, Awi D, Mendy M, Hill AV, Whittle H, McConkey SJ
PloS one 2011 Feb 15;6(2):e14626
PloS one 2011 Feb 15;6(2):e14626
In vivo expression of human T-lymphotropic virus type 1 basic leucine-zipper protein generates specific CD8+ and CD4+ T-lymphocyte responses that correlate with clinical outcome.
Hilburn S, Rowan A, Demontis MA, MacNamara A, Asquith B, Bangham CR, Taylor GP
The Journal of infectious diseases 2011 Feb 15;203(4):529-36
The Journal of infectious diseases 2011 Feb 15;203(4):529-36
Cellular immune responses in patients with hepatitis B surface antigen seroclearance induced by antiviral therapy.
Liang M, Ma S, Hu X, Zhou B, Zhang J, Chen J, Wang Z, Sun J, Zhu X, Abbott W, Hou J
Virology journal 2011 Feb 14;8:69
Virology journal 2011 Feb 14;8:69
Cytolytic T lymphocytes from HLA-B8+ donors frequently recognize the Hodgkin's lymphoma associated latent membrane protein 2 of Epstein Barr virus.
Tsang ML, Münz C
Herpesviridae 2011 Feb 11;2(1):4
Herpesviridae 2011 Feb 11;2(1):4
Alterations in immune function are associated with liver enzyme elevation in HIV and HCV co-infection after commencement of combination antiretroviral therapy.
Cameron BA, Emerson CR, Workman C, Kelly MD, Lloyd AR, Post JJ
Journal of clinical immunology 2011 Dec;31(6):1079-83
Journal of clinical immunology 2011 Dec;31(6):1079-83
Identification of three novel CTL epitopes within nucleocapsid protein of Hantaan virus.
Wang M, Zhu Y, Wang J, Lv T, Jin B
Viral immunology 2011 Dec;24(6):449-54
Viral immunology 2011 Dec;24(6):449-54
An engineered Plasmodium falciparum C-terminal 19-kilodalton merozoite surface protein 1 vaccine candidate induces high levels of interferon-gamma production associated with cellular immune responses to specific peptide sequences in Gambian adults naturally exposed to malaria.
Bisseye C, Yindom LM, Simporé J, Morgan WD, Holder AA, Ismaili J
Clinical and experimental immunology 2011 Dec;166(3):366-73
Clinical and experimental immunology 2011 Dec;166(3):366-73
Definition of the viral targets of protective HIV-1-specific T cell responses.
Mothe B, Llano A, Ibarrondo J, Daniels M, Miranda C, Zamarreño J, Bach V, Zuniga R, Pérez-Álvarez S, Berger CT, Puertas MC, Martinez-Picado J, Rolland M, Farfan M, Szinger JJ, Hildebrand WH, Yang OO, Sanchez-Merino V, Brumme CJ, Brumme ZL, Heckerman D, Allen TM, Mullins JI, Gómez G, Goulder PJ, Walker BD, Gatell JM, Clotet B, Korber BT, Sanchez J, Brander C
Journal of translational medicine 2011 Dec 7;9:208
Journal of translational medicine 2011 Dec 7;9:208
Pilot clinical trial of type 1 dendritic cells loaded with autologous tumor lysates combined with GM-CSF, pegylated IFN, and cyclophosphamide for metastatic cancer patients.
Alfaro C, Perez-Gracia JL, Suarez N, Rodriguez J, Fernandez de Sanmamed M, Sangro B, Martin-Algarra S, Calvo A, Redrado M, Agliano A, Gonzalez A, Rodriguez I, Bolaños E, Hervás-Stubbs S, Perez-Calvo J, Benito A, Peñuelas I, Vigil C, Richter J, Martinez-Forero I, Melero I
Journal of immunology (Baltimore, Md. : 1950) 2011 Dec 1;187(11):6130-42
Journal of immunology (Baltimore, Md. : 1950) 2011 Dec 1;187(11):6130-42
The immune response to the RT181-189 epitope in HIV-1-infected patients is associated with viral sequence polymorphism flanking the epitope.
Pacheco Y, Allavena C, Guilloux Y, Mueller-Schmucker SM, Hueckelhoven AG, André-Garnier E, Cleon F, Ferré V, Rodallec A, Billaud E, Harrer T, Raffi F, McIlroy D
Journal of clinical immunology 2011 Aug;31(4):681-9
Journal of clinical immunology 2011 Aug;31(4):681-9
Clinical significance of interleukin-2/gamma interferon ratios in Mycobacterium tuberculosis-specific T-cell signatures.
Suter-Riniker F, Berger A, Mayor D, Bittel P, Iseli P, Bodmer T
Clinical and vaccine immunology : CVI 2011 Aug;18(8):1395-6
Clinical and vaccine immunology : CVI 2011 Aug;18(8):1395-6
Bimodal ex vivo expansion of T cells from patients with head and neck squamous cell carcinoma: a prerequisite for adoptive cell transfer.
Junker N, Andersen MH, Wenandy L, Dombernowsky SL, Kiss K, Sørensen CH, Therkildsen MH, Von Buchwald C, Andersen E, Straten PT, Svane IM
Cytotherapy 2011 Aug;13(7):822-34
Cytotherapy 2011 Aug;13(7):822-34
A whole blood monokine-based reporter assay provides a sensitive and robust measurement of the antigen-specific T cell response.
Chakera A, Bennett SC, Cornall RJ
Journal of translational medicine 2011 Aug 26;9:143
Journal of translational medicine 2011 Aug 26;9:143
Precursor frequency and competition dictate the HLA-A2-restricted CD8+ T cell responses to influenza A infection and vaccination in HLA-A2.1 transgenic mice.
Tan AC, La Gruta NL, Zeng W, Jackson DC
Journal of immunology (Baltimore, Md. : 1950) 2011 Aug 15;187(4):1895-902
Journal of immunology (Baltimore, Md. : 1950) 2011 Aug 15;187(4):1895-902
Human epidermal Langerhans cells replenish skin xenografts and are depleted by alloreactive T cells in vivo.
Hemmerling J, Wegner-Kops J, von Stebut E, Wolff D, Wagner EM, Hartwig UF, André MC, Theobald M, Schopf RE, Herr W, Meyer RG
Journal of immunology (Baltimore, Md. : 1950) 2011 Aug 1;187(3):1142-9
Journal of immunology (Baltimore, Md. : 1950) 2011 Aug 1;187(3):1142-9
Differences in HIV-specific T cell responses between HIV-exposed and -unexposed HIV-seronegative individuals.
Ritchie AJ, Campion SL, Kopycinski J, Moodie Z, Wang ZM, Pandya K, Moore S, Liu MK, Brackenridge S, Kuldanek K, Legg K, Cohen MS, Delwart EL, Haynes BF, Fidler S, McMichael AJ, Goonetilleke N
Journal of virology 2011 Apr;85(7):3507-16
Journal of virology 2011 Apr;85(7):3507-16
Deficiency of activated STAT1 in head and neck cancer cells mediates TAP1-dependent escape from cytotoxic T lymphocytes.
Leibowitz MS, Andrade Filho PA, Ferrone S, Ferris RL
Cancer immunology, immunotherapy : CII 2011 Apr;60(4):525-35
Cancer immunology, immunotherapy : CII 2011 Apr;60(4):525-35
Altered decamer and nonamer from an HLA-A0201-restricted epitope of Survivin differentially stimulate T-cell responses in different individuals.
Bernatchez C, Zhu K, Li Y, Andersson H, Ionnides C, Fernandez-Vina M, Cano P, Cooper L, Abbruzzese J, Hwu P, Chang DZ, Radvanyi LG
Vaccine 2011 Apr 5;29(16):3021-30
Vaccine 2011 Apr 5;29(16):3021-30
Rv3615c is a highly immunodominant RD1 (Region of Difference 1)-dependent secreted antigen specific for Mycobacterium tuberculosis infection.
Millington KA, Fortune SM, Low J, Garces A, Hingley-Wilson SM, Wickremasinghe M, Kon OM, Lalvani A
Proceedings of the National Academy of Sciences of the United States of America 2011 Apr 5;108(14):5730-5
Proceedings of the National Academy of Sciences of the United States of America 2011 Apr 5;108(14):5730-5
HTLV-1 tax specific CD8+ T cells express low levels of Tim-3 in HTLV-1 infection: implications for progression to neurological complications.
Ndhlovu LC, Leal FE, Hasenkrug AM, Jha AR, Carvalho KI, Eccles-James IG, Bruno FR, Vieira RG, York VA, Chew GM, Jones RB, Tanaka Y, Neto WK, Sanabani SS, Ostrowski MA, Segurado AC, Nixon DF, Kallas EG
PLoS neglected tropical diseases 2011 Apr 26;5(4):e1030
PLoS neglected tropical diseases 2011 Apr 26;5(4):e1030
Differential cellular recognition of antigens during acute Plasmodium falciparum and Plasmodium vivax malaria.
Salwati E, Minigo G, Woodberry T, Piera KA, de Silva HD, Kenangalem E, Tjitra E, Coppel RL, Price RN, Anstey NM, Plebanski M
The Journal of infectious diseases 2011 Apr 15;203(8):1192-1199
The Journal of infectious diseases 2011 Apr 15;203(8):1192-1199
Peptide-loaded Langerhans cells, despite increased IL15 secretion and T-cell activation in vitro, elicit antitumor T-cell responses comparable to peptide-loaded monocyte-derived dendritic cells in vivo.
Romano E, Rossi M, Ratzinger G, de Cos MA, Chung DJ, Panageas KS, Wolchok JD, Houghton AN, Chapman PB, Heller G, Yuan J, Young JW
Clinical cancer research : an official journal of the American Association for Cancer Research 2011 Apr 1;17(7):1984-97
Clinical cancer research : an official journal of the American Association for Cancer Research 2011 Apr 1;17(7):1984-97
JAK3/STAT5/6 pathway alterations are associated with immune deviation in CD8 T cells in renal cell carcinoma patients.
Cavalcanti E, Gigante M, Mancini V, Battaglia M, Ditonno P, Capobianco C, Cincione RI, Selvaggi FP, Herr W, Storkus WJ, Gesualdo L, Ranieri E
Journal of biomedicine & biotechnology 2010;2010:935764
Journal of biomedicine & biotechnology 2010;2010:935764
Identification of an MSI-H tumor-specific cytotoxic T cell epitope generated by the (-1) frame of U79260(FTO).
Linnebacher M, Wienck A, Boeck I, Klar E
Journal of biomedicine & biotechnology 2010;2010:841451
Journal of biomedicine & biotechnology 2010;2010:841451
Risk factors and immune response to hepatitis E viral infection among acute hepatitis patients in Assiut, Egypt.
Eldin SS, Seddik I, Daef EA, Shata MT, Raafat M, Abdel Baky L, Nafeh MA
The Egyptian journal of immunology 2010;17(1):73-86
The Egyptian journal of immunology 2010;17(1):73-86
Diversity in CD8(+) T cell function and epitope breadth among persons with genital herpes.
Laing KJ, Magaret AS, Mueller DE, Zhao L, Johnston C, De Rosa SC, Koelle DM, Wald A, Corey L
Journal of clinical immunology 2010 Sep;30(5):703-22
Journal of clinical immunology 2010 Sep;30(5):703-22
IL-2 immunotherapy to recently HIV-1 infected adults maintains the numbers of IL-17 expressing CD4+ T (T(H)17) cells in the periphery.
Ndhlovu LC, Sinclair E, Epling L, Tan QX, Ho T, Jha AR, Eccles-James I, Tincati C, Levy JA, Nixon DF, Hecht FM, Barbour JD
Journal of clinical immunology 2010 Sep;30(5):681-92
Journal of clinical immunology 2010 Sep;30(5):681-92
Efficacy of dendritic cells matured early with OK-432 (Picibanil), prostaglandin E2, and interferon-alpha as a vaccine for a hormone refractory prostate cancer cell line.
Yoo C, Do HA, Jeong IG, Park H, Hwang JJ, Hong JH, Cho JS, Choo MS, Ahn H, Kim CS
Journal of Korean medical science 2010 Sep;25(9):1284-90
Journal of Korean medical science 2010 Sep;25(9):1284-90
Comparison of immunologic assays for detecting immune responses in HIV immunotherapeutic studies: AIDS Clinical Trials Group Trial A5181.
Macatangay BJ, Zheng L, Rinaldo CR, Landay AL, Pollard RB, Pahwa S, Lederman MM, Bucy RP
Clinical and vaccine immunology : CVI 2010 Sep;17(9):1452-9
Clinical and vaccine immunology : CVI 2010 Sep;17(9):1452-9
HLA class I binding of HBZ determines outcome in HTLV-1 infection.
Macnamara A, Rowan A, Hilburn S, Kadolsky U, Fujiwara H, Suemori K, Yasukawa M, Taylor G, Bangham CR, Asquith B
PLoS pathogens 2010 Sep 23;6(9):e1001117
PLoS pathogens 2010 Sep 23;6(9):e1001117
Dendritic cells reveal a broad range of MHC class I epitopes for HIV-1 in persons with suppressed viral load on antiretroviral therapy.
Huang XL, Fan Z, Borowski L, Mailliard RB, Rolland M, Mullins JI, Day RD, Rinaldo CR
PloS one 2010 Sep 23;5(9):e12936
PloS one 2010 Sep 23;5(9):e12936
A conserved E7-derived cytotoxic T lymphocyte epitope expressed on human papillomavirus 16-transformed HLA-A2+ epithelial cancers.
Riemer AB, Keskin DB, Zhang G, Handley M, Anderson KS, Brusic V, Reinhold B, Reinherz EL
The Journal of biological chemistry 2010 Sep 17;285(38):29608-22
The Journal of biological chemistry 2010 Sep 17;285(38):29608-22
Dynamic correlation between CTL response and viral load in primary human immunodeficiency virus-1 infected Koreans.
Kim GJ, Lee HS, Hong KJ, Kim SS
Virology journal 2010 Sep 16;7:239
Virology journal 2010 Sep 16;7:239
Immunodominant HIV-specific CD8+ T-cell responses are common to blood and gastrointestinal mucosa, and Gag-specific responses dominate in rectal mucosa of HIV controllers.
Ferre AL, Lemongello D, Hunt PW, Morris MM, Garcia JC, Pollard RB, Yee HF Jr, Martin JN, Deeks SG, Shacklett BL
Journal of virology 2010 Oct;84(19):10354-65
Journal of virology 2010 Oct;84(19):10354-65
CD8+ T cell recognition of polymorphic wild-type sequence p53(65-73) peptides in squamous cell carcinoma of the head and neck.
Andrade Filho PA, Ito D, Deleo AB, Ferris RL
Cancer immunology, immunotherapy : CII 2010 Oct;59(10):1561-8
Cancer immunology, immunotherapy : CII 2010 Oct;59(10):1561-8
Treatment of cancer patients with a serotype 5/3 chimeric oncolytic adenovirus expressing GMCSF.
Koski A, Kangasniemi L, Escutenaire S, Pesonen S, Cerullo V, Diaconu I, Nokisalmi P, Raki M, Rajecki M, Guse K, Ranki T, Oksanen M, Holm SL, Haavisto E, Karioja-Kallio A, Laasonen L, Partanen K, Ugolini M, Helminen A, Karli E, Hannuksela P, Pesonen S, Joensuu T, Kanerva A, Hemminki A
Molecular therapy : the journal of the American Society of Gene Therapy 2010 Oct;18(10):1874-84
Molecular therapy : the journal of the American Society of Gene Therapy 2010 Oct;18(10):1874-84
Monofunctional and polyfunctional CD8+ T cell responses to human herpesvirus 8 lytic and latency proteins.
Lepone L, Rappocciolo G, Knowlton E, Jais M, Piazza P, Jenkins FJ, Rinaldo CR
Clinical and vaccine immunology : CVI 2010 Oct;17(10):1507-16
Clinical and vaccine immunology : CVI 2010 Oct;17(10):1507-16
Methanol induces a discrete transcriptional dysregulation that leads to cytokine overproduction in activated lymphocytes.
Désy O, Carignan D, Caruso M, de Campos-Lima PO
Toxicological sciences : an official journal of the Society of Toxicology 2010 Oct;117(2):303-13
Toxicological sciences : an official journal of the Society of Toxicology 2010 Oct;117(2):303-13
Safety and immunogenicity of a replication-defective adenovirus type 5 HIV vaccine in Ad5-seronegative persons: a randomized clinical trial (HVTN 054).
Peiperl L, Morgan C, Moodie Z, Li H, Russell N, Graham BS, Tomaras GD, De Rosa SC, McElrath MJ, NIAID HIV Vaccine Trials Network
PloS one 2010 Oct 27;5(10):e13579
PloS one 2010 Oct 27;5(10):e13579
CD8 controls T cell cross-reactivity.
Wooldridge L, Laugel B, Ekeruche J, Clement M, van den Berg HA, Price DA, Sewell AK
Journal of immunology (Baltimore, Md. : 1950) 2010 Oct 15;185(8):4625-32
Journal of immunology (Baltimore, Md. : 1950) 2010 Oct 15;185(8):4625-32
CD8+ T cells as a source of IFN-γ production in human cutaneous leishmaniasis.
Nateghi Rostami M, Keshavarz H, Edalat R, Sarrafnejad A, Shahrestani T, Mahboudi F, Khamesipour A
PLoS neglected tropical diseases 2010 Oct 12;4(10):e845
PLoS neglected tropical diseases 2010 Oct 12;4(10):e845
Screening of human tumor antigens for CD4 T cell epitopes by combination of HLA-transgenic mice, recombinant adenovirus and antigen peptide libraries.
Osen W, Soltek S, Song M, Leuchs B, Steitz J, Tüting T, Eichmüller SB, Nguyen XD, Schadendorf D, Paschen A
PloS one 2010 Nov 30;5(11):e14137
PloS one 2010 Nov 30;5(11):e14137
A comprehensive ex vivo functional analysis of human NKT cells reveals production of MIP1-α and MIP1-β, a lack of IL-17, and a Th1-bias in males.
Snyder-Cappione JE, Tincati C, Eccles-James IG, Cappione AJ, Ndhlovu LC, Koth LL, Nixon DF
PloS one 2010 Nov 3;5(11):e15412
PloS one 2010 Nov 3;5(11):e15412
Phase I safety and immunogenicity evaluation of MVA-CMDR, a multigenic, recombinant modified vaccinia Ankara-HIV-1 vaccine candidate.
Currier JR, Ngauy V, de Souza MS, Ratto-Kim S, Cox JH, Polonis VR, Earl P, Moss B, Peel S, Slike B, Sriplienchan S, Thongcharoen P, Paris RM, Robb ML, Kim J, Michael NL, Marovich MA
PloS one 2010 Nov 15;5(11):e13983
PloS one 2010 Nov 15;5(11):e13983
A randomized trial of ex vivo CD40L activation of a dendritic cell vaccine in colorectal cancer patients: tumor-specific immune responses are associated with improved survival.
Barth RJ Jr, Fisher DA, Wallace PK, Channon JY, Noelle RJ, Gui J, Ernstoff MS
Clinical cancer research : an official journal of the American Association for Cancer Research 2010 Nov 15;16(22):5548-56
Clinical cancer research : an official journal of the American Association for Cancer Research 2010 Nov 15;16(22):5548-56
Virus-specific CD8+ T-cell responses better define HIV disease progression than HLA genotype.
Dinges WL, Richardt J, Friedrich D, Jalbert E, Liu Y, Stevens CE, Maenza J, Collier AC, Geraghty DE, Smith J, Moodie Z, Mullins JI, McElrath MJ, Horton H
Journal of virology 2010 May;84(9):4461-8
Journal of virology 2010 May;84(9):4461-8
Identification of broad binding class I HLA supertype epitopes to provide universal coverage of influenza A virus.
Alexander J, Bilsel P, del Guercio MF, Marinkovic-Petrovic A, Southwood S, Stewart S, Ishioka G, Kotturi MF, Botten J, Sidney J, Newman M, Sette A
Human immunology 2010 May;71(5):468-74
Human immunology 2010 May;71(5):468-74
Naturally occurring systemic immune responses to HPV antigens do not predict regression of CIN2/3.
Trimble CL, Peng S, Thoburn C, Kos F, Wu TC
Cancer immunology, immunotherapy : CII 2010 May;59(5):799-803
Cancer immunology, immunotherapy : CII 2010 May;59(5):799-803
3-hydroxyphthalic anhydride-modified chicken ovalbumin exhibits potent and broad anti-HIV-1 activity: a potential microbicide for preventing sexual transmission of HIV-1.
Li L, He L, Tan S, Guo X, Lu H, Qi Z, Pan C, An X, Jiang S, Liu S
Antimicrobial agents and chemotherapy 2010 May;54(5):1700-11
Antimicrobial agents and chemotherapy 2010 May;54(5):1700-11
Polyclonal expansion of cervical cytobrush-derived T cells to investigate HIV-specific responses in the female genital tract.
Bere A, Denny L, Burgers WA, Passmore JA
Immunology 2010 May;130(1):23-33
Immunology 2010 May;130(1):23-33
Human immunodeficiency virus-1 inhibition of immunoamphisomes in dendritic cells impairs early innate and adaptive immune responses.
Blanchet FP, Moris A, Nikolic DS, Lehmann M, Cardinaud S, Stalder R, Garcia E, Dinkins C, Leuba F, Wu L, Schwartz O, Deretic V, Piguet V
Immunity 2010 May 28;32(5):654-69
Immunity 2010 May 28;32(5):654-69
Reversion and conversion of Mycobacterium tuberculosis IFN-gamma ELISpot results during anti-tuberculous treatment in HIV-infected children.
Connell TG, Davies MA, Johannisen C, Wood K, Pienaar S, Wilkinson KA, Wilkinson RJ, Zar HJ, Beatty D, Nicol MP, Curtis N, Eley B
BMC infectious diseases 2010 May 27;10:138
BMC infectious diseases 2010 May 27;10:138
Human immunodeficiency virus type I-specific CD8+ T cell subset abnormalities in chronic infection persist through effective antiretroviral therapy.
Pohling J, Zipperlen K, Hollett NA, Gallant ME, Grant MD
BMC infectious diseases 2010 May 25;10:129
BMC infectious diseases 2010 May 25;10:129
Identification of T. gondii epitopes, adjuvants, and host genetic factors that influence protection of mice and humans.
Tan TG, Mui E, Cong H, Witola WH, Montpetit A, Muench SP, Sidney J, Alexander J, Sette A, Grigg ME, Maewal A, McLeod R
Vaccine 2010 May 21;28(23):3977-89
Vaccine 2010 May 21;28(23):3977-89
Construction and immunogenicity of replication-competent adenovirus 5 host range mutant recombinants expressing HIV-1 gp160 of SF162 and TV1 strains.
Hidajat R, Kuate S, Venzon D, Kalyanaraman V, Kalisz I, Treece J, Lian Y, Barnett SW, Robert-Guroff M
Vaccine 2010 May 21;28(23):3963-71
Vaccine 2010 May 21;28(23):3963-71
Graft-versus-leukemia antigen CML66 elicits coordinated B-cell and T-cell immunity after donor lymphocyte infusion.
Zhang W, Choi J, Zeng W, Rogers SA, Alyea EP, Rheinwald JG, Canning CM, Brusic V, Sasada T, Reinherz EL, Ritz J, Soiffer RJ, Wu CJ
Clinical cancer research : an official journal of the American Association for Cancer Research 2010 May 15;16(10):2729-39
Clinical cancer research : an official journal of the American Association for Cancer Research 2010 May 15;16(10):2729-39
Human immunodeficiency virus (HIV) infection during pregnancy induces CD4 T-cell differentiation and modulates responses to Bacille Calmette-Guérin (BCG) vaccine in HIV-uninfected infants.
Miles DJ, Gadama L, Gumbi A, Nyalo F, Makanani B, Heyderman RS
Immunology 2010 Mar;129(3):446-54
Immunology 2010 Mar;129(3):446-54
Detailed characterization of T cell responses to herpes simplex virus-2 in immune seronegative persons.
Posavad CM, Remington M, Mueller DE, Zhao L, Magaret AS, Wald A, Corey L
Journal of immunology (Baltimore, Md. : 1950) 2010 Mar 15;184(6):3250-9
Journal of immunology (Baltimore, Md. : 1950) 2010 Mar 15;184(6):3250-9
Anti-inflammatory triterpenoid blocks immune suppressive function of MDSCs and improves immune response in cancer.
Nagaraj S, Youn JI, Weber H, Iclozan C, Lu L, Cotter MJ, Meyer C, Becerra CR, Fishman M, Antonia S, Sporn MB, Liby KT, Rawal B, Lee JH, Gabrilovich DI
Clinical cancer research : an official journal of the American Association for Cancer Research 2010 Mar 15;16(6):1812-23
Clinical cancer research : an official journal of the American Association for Cancer Research 2010 Mar 15;16(6):1812-23
Virological footprint of CD4+ T-cell responses during chronic hepatitis C virus infection.
Fleming VM, Harcourt G, Barnes E, Klenerman P
The Journal of general virology 2010 Jun;91(Pt 6):1396-406
The Journal of general virology 2010 Jun;91(Pt 6):1396-406
Enhanced anti-HIV functional activity associated with Gag-specific CD8 T-cell responses.
Julg B, Williams KL, Reddy S, Bishop K, Qi Y, Carrington M, Goulder PJ, Ndung'u T, Walker BD
Journal of virology 2010 Jun;84(11):5540-9
Journal of virology 2010 Jun;84(11):5540-9
Different in vivo effects of HIV-1 immunodominant epitope-specific cytotoxic T lymphocytes on selection of escape mutant viruses.
Koizumi H, Hashimoto M, Fujiwara M, Murakoshi H, Chikata T, Borghan MA, Hachiya A, Kawashima Y, Takata H, Ueno T, Oka S, Takiguchi M
Journal of virology 2010 Jun;84(11):5508-19
Journal of virology 2010 Jun;84(11):5508-19
HLA-A2-restricted T-cell epitopes specific for prostatic acid phosphatase.
Olson BM, Frye TP, Johnson LE, Fong L, Knutson KL, Disis ML, McNeel DG
Cancer immunology, immunotherapy : CII 2010 Jun;59(6):943-53
Cancer immunology, immunotherapy : CII 2010 Jun;59(6):943-53
Development of a cross-platform biomarker signature to detect renal transplant tolerance in humans.
Sagoo P, Perucha E, Sawitzki B, Tomiuk S, Stephens DA, Miqueu P, Chapman S, Craciun L, Sergeant R, Brouard S, Rovis F, Jimenez E, Ballow A, Giral M, Rebollo-Mesa I, Le Moine A, Braudeau C, Hilton R, Gerstmayer B, Bourcier K, Sharif A, Krajewska M, Lord GM, Roberts I, Goldman M, Wood KJ, Newell K, Seyfert-Margolis V, Warrens AN, Janssen U, Volk HD, Soulillou JP, Hernandez-Fuentes MP, Lechler RI
The Journal of clinical investigation 2010 Jun;120(6):1848-61
The Journal of clinical investigation 2010 Jun;120(6):1848-61
Vaccination with a plasmid DNA encoding HER-2/neu together with low doses of GM-CSF and IL-2 in patients with metastatic breast carcinoma: a pilot clinical trial.
Norell H, Poschke I, Charo J, Wei WZ, Erskine C, Piechocki MP, Knutson KL, Bergh J, Lidbrink E, Kiessling R
Journal of translational medicine 2010 Jun 7;8:53
Journal of translational medicine 2010 Jun 7;8:53
The small molecule curcumin analog FLLL32 induces apoptosis in melanoma cells via STAT3 inhibition and retains the cellular response to cytokines with anti-tumor activity.
Bill MA, Fuchs JR, Li C, Yui J, Bakan C, Benson DM Jr, Schwartz EB, Abdelhamid D, Lin J, Hoyt DG, Fossey SL, Young GS, Carson WE 3rd, Li PK, Lesinski GB
Molecular cancer 2010 Jun 25;9:165
Molecular cancer 2010 Jun 25;9:165
Correlates of spontaneous viral control among long-term survivors of perinatal HIV-1 infection expressing human leukocyte antigen-B57.
Tang Y, Huang S, Dunkley-Thompson J, Steel-Duncan JC, Ryland EG, St John MA, Hazra R, Christie CD, Feeney ME
AIDS (London, England) 2010 Jun 19;24(10):1425-35
AIDS (London, England) 2010 Jun 19;24(10):1425-35
Synergism from combined immunologic and pharmacologic inhibition of HER2 in vivo.
Morse MA, Wei J, Hartman Z, Xia W, Ren XR, Lei G, Barry WT, Osada T, Hobeika AC, Peplinski S, Jiang H, Devi GR, Chen W, Spector N, Amalfitano A, Lyerly HK, Clay TM
International journal of cancer 2010 Jun 15;126(12):2893-903
International journal of cancer 2010 Jun 15;126(12):2893-903
Control of HIV-1 in elite suppressors despite ongoing replication and evolution in plasma virus.
O'Connell KA, Brennan TP, Bailey JR, Ray SC, Siliciano RF, Blankson JN
Journal of virology 2010 Jul;84(14):7018-28
Journal of virology 2010 Jul;84(14):7018-28
Variation in gamma interferon responses to different infecting strains of Mycobacterium tuberculosis in acid-fast bacillus smear-positive patients and household contacts in Antananarivo, Madagascar.
Rakotosamimanana N, Raharimanga V, Andriamandimby SF, Soares JL, Doherty TM, Ratsitorahina M, Ramarokoto H, Zumla A, Huggett J, Rook G, Richard V, Gicquel B, Rasolofo-Razanamparany V, VACSEL/VACSIS Study Group
Clinical and vaccine immunology : CVI 2010 Jul;17(7):1094-103
Clinical and vaccine immunology : CVI 2010 Jul;17(7):1094-103
Virally infected and matured human dendritic cells activate natural killer cells via cooperative activity of plasma membrane-bound TNF and IL-15.
Vujanovic L, Szymkowski DE, Alber S, Watkins SC, Vujanovic NL, Butterfield LH
Blood 2010 Jul 29;116(4):575-83
Blood 2010 Jul 29;116(4):575-83
An investigation of clinical and immunological events following repeated aerodigestive tract challenge infections with live Mycobacterium bovis Bacille Calmette Guérin.
Schreiber F, Huo Z, Giemza R, Woodrow M, Fenner N, Stephens Z, Dougan G, Prideaux S, Castello-Branco LR, Lewis DJ
Vaccine 2010 Jul 26;28(33):5427-31
Vaccine 2010 Jul 26;28(33):5427-31
Unexpected diversity of cellular immune responses against Nef and Vif in HIV-1-infected patients who spontaneously control viral replication.
Tarosso LF, Sauer MM, Sanabani S, Giret MT, Tomiyama HI, Sidney J, Piaskowski SM, Diaz RS, Sabino EC, Sette A, Kalil-Filho J, Watkins DI, Kallas EG
PloS one 2010 Jul 2;5(7):e11436
PloS one 2010 Jul 2;5(7):e11436
Molecular determinants of T cell epitope recognition to the common Timothy grass allergen.
Oseroff C, Sidney J, Kotturi MF, Kolla R, Alam R, Broide DH, Wasserman SI, Weiskopf D, McKinney DM, Chung JL, Petersen A, Grey H, Peters B, Sette A
Journal of immunology (Baltimore, Md. : 1950) 2010 Jul 15;185(2):943-55
Journal of immunology (Baltimore, Md. : 1950) 2010 Jul 15;185(2):943-55
Vaccination with synthetic analog peptides derived from WT1 oncoprotein induces T-cell responses in patients with complete remission from acute myeloid leukemia.
Maslak PG, Dao T, Krug LM, Chanel S, Korontsvit T, Zakhaleva V, Zhang R, Wolchok JD, Yuan J, Pinilla-Ibarz J, Berman E, Weiss M, Jurcic J, Frattini MG, Scheinberg DA
Blood 2010 Jul 15;116(2):171-9
Blood 2010 Jul 15;116(2):171-9
Could a loss of memory T cells limit responses to hepatitis C virus (HCV) antigens in blood leucocytes from patients chronically infected with HCV before and during pegylated interferon-alpha and ribavirin therapy?
Lee S, Hammond T, Watson MW, Flexman JP, Cheng W, Fernandez S, Price P
Clinical and experimental immunology 2010 Jul 1;161(1):118-26
Clinical and experimental immunology 2010 Jul 1;161(1):118-26
Novel approach to the formulation of an Epstein-Barr virus antigen-based nasopharyngeal carcinoma vaccine.
Lutzky VP, Corban M, Heslop L, Morrison LE, Crooks P, Hall DF, Coman WB, Thomson SA, Moss DJ
Journal of virology 2010 Jan;84(1):407-17
Journal of virology 2010 Jan;84(1):407-17
Modified vaccinia Ankara-expressing Ag85A, a novel tuberculosis vaccine, is safe in adolescents and children, and induces polyfunctional CD4+ T cells.
Scriba TJ, Tameris M, Mansoor N, Smit E, van der Merwe L, Isaacs F, Keyser A, Moyo S, Brittain N, Lawrie A, Gelderbloem S, Veldsman A, Hatherill M, Hawkridge A, Hill AV, Hussey GD, Mahomed H, McShane H, Hanekom WA
European journal of immunology 2010 Jan;40(1):279-90
European journal of immunology 2010 Jan;40(1):279-90
Novel immunogenic HLA-A*0201-restricted epidermal growth factor receptor-specific T-cell epitope in head and neck cancer patients.
Andrade Filho PA, López-Albaitero A, Gooding W, Ferris RL
Journal of immunotherapy (Hagerstown, Md. : 1997) 2010 Jan;33(1):83-91
Journal of immunotherapy (Hagerstown, Md. : 1997) 2010 Jan;33(1):83-91
Cellular immune responses against CT7 (MAGE-C1) and humoral responses against other cancer-testis antigens in multiple myeloma patients.
Lendvai N, Gnjatic S, Ritter E, Mangone M, Austin W, Reyner K, Jayabalan D, Niesvizky R, Jagannath S, Bhardwaj N, Chen-Kiang S, Old LJ, Cho HJ
Cancer immunity 2010 Jan 29;10:4
Cancer immunity 2010 Jan 29;10:4
A pilot clinical trial testing mutant von Hippel-Lindau peptide as a novel immune therapy in metastatic renal cell carcinoma.
Rahma OE, Ashtar E, Ibrahim R, Toubaji A, Gause B, Herrin VE, Linehan WM, Steinberg SM, Grollman F, Grimes G, Bernstein SA, Berzofsky JA, Khleif SN
Journal of translational medicine 2010 Jan 28;8:8
Journal of translational medicine 2010 Jan 28;8:8
Viral adaptation to immune selection pressure by HLA class I-restricted CTL responses targeting epitopes in HIV frameshift sequences.
Berger CT, Carlson JM, Brumme CJ, Hartman KL, Brumme ZL, Henry LM, Rosato PC, Piechocka-Trocha A, Brockman MA, Harrigan PR, Heckerman D, Kaufmann DE, Brander C
The Journal of experimental medicine 2010 Jan 18;207(1):61-75
The Journal of experimental medicine 2010 Jan 18;207(1):61-75
Elevated Epstein-Barr virus-encoded nuclear antigen-1 immune responses predict conversion to multiple sclerosis.
Lünemann JD, Tintoré M, Messmer B, Strowig T, Rovira A, Perkal H, Caballero E, Münz C, Montalban X, Comabella M
Annals of neurology 2010 Feb;67(2):159-69
Annals of neurology 2010 Feb;67(2):159-69
Hepatocellular carcinoma immunopathogenesis: clinical evidence for global T cell defects and an immunomodulatory role for soluble CD25 (sCD25).
Cabrera R, Ararat M, Cao M, Xu Y, Wasserfall C, Atkinson MA, Liu C, Nelson DR
Digestive diseases and sciences 2010 Feb;55(2):484-95
Digestive diseases and sciences 2010 Feb;55(2):484-95
The establishment of dendritic cell-tumor fusion vaccines for hormone refractory prostate cancer cell.
Kim TB, Park HK, Chang JH, Choi IH, Kim KH, Yoon SJ, Lee MS, Jung H, Kim CS
Korean journal of urology 2010 Feb;51(2):139-44
Korean journal of urology 2010 Feb;51(2):139-44
DC expressing transgene Foxp3 are regulatory APC.
Lipscomb MW, Taylor JL, Goldbach CJ, Watkins SC, Wesa AK, Storkus WJ
European journal of immunology 2010 Feb;40(2):480-93
European journal of immunology 2010 Feb;40(2):480-93
HIV controller CD4+ T cells respond to minimal amounts of Gag antigen due to high TCR avidity.
Vingert B, Perez-Patrigeon S, Jeannin P, Lambotte O, Boufassa F, Lemaître F, Kwok WW, Theodorou I, Delfraissy JF, Thèze J, Chakrabarti LA, ANRS EP36 HIV Controllers Study Group
PLoS pathogens 2010 Feb 26;6(2):e1000780
PLoS pathogens 2010 Feb 26;6(2):e1000780
Healthy human T-Cell Responses to Aspergillus fumigatus antigens.
Chaudhary N, Staab JF, Marr KA
PloS one 2010 Feb 17;5(2):e9036
PloS one 2010 Feb 17;5(2):e9036
A case of seronegative HIV-1 infection.
Spivak AM, Brennan TP, O'Connell KA, Sydnor E, Williams TM, Siliciano RF, Gallant JE, Blankson JN
The Journal of infectious diseases 2010 Feb 1;201(3):341-5
The Journal of infectious diseases 2010 Feb 1;201(3):341-5
Peripheral blood invariant natural killer T cells throughout pregnancy and in preeclamptic women.
Southcombe J, Redman C, Sargent I
Journal of reproductive immunology 2010 Dec;87(1-2):52-9
Journal of reproductive immunology 2010 Dec;87(1-2):52-9
Sequence evolution of HIV-1 following mother-to-child transmission.
Ryland EG, Tang Y, Christie CD, Feeney ME
Journal of virology 2010 Dec;84(23):12437-44
Journal of virology 2010 Dec;84(23):12437-44
CD1a-autoreactive T cells are a normal component of the human αβ T cell repertoire.
de Jong A, Peña-Cruz V, Cheng TY, Clark RA, Van Rhijn I, Moody DB
Nature immunology 2010 Dec;11(12):1102-9
Nature immunology 2010 Dec;11(12):1102-9
Human immunome, bioinformatic analyses using HLA supermotifs and the parasite genome, binding assays, studies of human T cell responses, and immunization of HLA-A*1101 transgenic mice including novel adjuvants provide a foundation for HLA-A03 restricted CD8+T cell epitope based, adjuvanted vaccine protective against Toxoplasma gondii.
Cong H, Mui EJ, Witola WH, Sidney J, Alexander J, Sette A, Maewal A, McLeod R
Immunome research 2010 Dec 3;6:12
Immunome research 2010 Dec 3;6:12
Hypoxia induces an immunodominant target of tuberculosis specific T cells absent from common BCG vaccines.
Gideon HP, Wilkinson KA, Rustad TR, Oni T, Guio H, Kozak RA, Sherman DR, Meintjes G, Behr MA, Vordermeier HM, Young DB, Wilkinson RJ
PLoS pathogens 2010 Dec 23;6(12):e1001237
PLoS pathogens 2010 Dec 23;6(12):e1001237
Optimization of storage and shipment of cryopreserved peripheral blood mononuclear cells from HIV-infected and uninfected individuals for ELISPOT assays.
Weinberg A, Song LY, Wilkening CL, Fenton T, Hural J, Louzao R, Ferrari G, Etter PE, Berrong M, Canniff JD, Carter D, Defawe OD, Garcia A, Garrelts TL, Gelman R, Lambrecht LK, Pahwa S, Pilakka-Kanthikeel S, Shugarts DL, Tustin NB
Journal of immunological methods 2010 Dec 15;363(1):42-50
Journal of immunological methods 2010 Dec 15;363(1):42-50
Enumeration of functional T-cell subsets by fluorescence-immunospot defines signatures of pathogen burden in tuberculosis.
Casey R, Blumenkrantz D, Millington K, Montamat-Sicotte D, Kon OM, Wickremasinghe M, Bremang S, Magtoto M, Sridhar S, Connell D, Lalvani A
PloS one 2010 Dec 14;5(12):e15619
PloS one 2010 Dec 14;5(12):e15619
Equivalence of ELISpot assays demonstrated between major HIV network laboratories.
Gill DK, Huang Y, Levine GL, Sambor A, Carter DK, Sato A, Kopycinski J, Hayes P, Hahn B, Birungi J, Tarragona-Fiol T, Wan H, Randles M, Cooper AR, Ssemaganda A, Clark L, Kaleebu P, Self SG, Koup R, Wood B, McElrath MJ, Cox JH, Hural J, Gilmour J
PloS one 2010 Dec 14;5(12):e14330
PloS one 2010 Dec 14;5(12):e14330
Fine analysis of spontaneous MAGE-C1/CT7-specific immunity in melanoma patients.
Nuber N, Curioni-Fontecedro A, Matter C, Soldini D, Tiercy JM, von Boehmer L, Moch H, Dummer R, Knuth A, van den Broek M
Proceedings of the National Academy of Sciences of the United States of America 2010 Aug 24;107(34):15187-92
Proceedings of the National Academy of Sciences of the United States of America 2010 Aug 24;107(34):15187-92
Cerebrospinal T-cell responses aid in the diagnosis of tuberculous meningitis in a human immunodeficiency virus- and tuberculosis-endemic population.
Patel VB, Singh R, Connolly C, Coovadia Y, Peer AK, Parag P, Kasprowicz V, Zumla A, Ndung'u T, Dheda K
American journal of respiratory and critical care medicine 2010 Aug 15;182(4):569-77
American journal of respiratory and critical care medicine 2010 Aug 15;182(4):569-77
Inverse correlation of HER2 with MHC class I expression on oesophageal squamous cell carcinoma.
Maruyama T, Mimura K, Sato E, Watanabe M, Mizukami Y, Kawaguchi Y, Ando T, Kinouchi H, Fujii H, Kono K
British journal of cancer 2010 Aug 10;103(4):552-9
British journal of cancer 2010 Aug 10;103(4):552-9
Serum is not required for ex vivo IFN-gamma ELISPOT: a collaborative study of different protocols from the European CIMT Immunoguiding Program.
Mander A, Gouttefangeas C, Ottensmeier C, Welters MJ, Low L, van der Burg SH, Britten CM
Cancer immunology, immunotherapy : CII 2010 Apr;59(4):619-27
Cancer immunology, immunotherapy : CII 2010 Apr;59(4):619-27
Performance of serum-supplemented and serum-free media in IFNgamma Elispot Assays for human T cells.
Janetzki S, Price L, Britten CM, van der Burg SH, Caterini J, Currier JR, Ferrari G, Gouttefangeas C, Hayes P, Kaempgen E, Lennerz V, Nihlmark K, Souza V, Hoos A
Cancer immunology, immunotherapy : CII 2010 Apr;59(4):609-18
Cancer immunology, immunotherapy : CII 2010 Apr;59(4):609-18
Accelerated production of antigen-specific T cells for preclinical and clinical applications using gas-permeable rapid expansion cultureware (G-Rex).
Vera JF, Brenner LJ, Gerdemann U, Ngo MC, Sili U, Liu H, Wilson J, Dotti G, Heslop HE, Leen AM, Rooney CM
Journal of immunotherapy (Hagerstown, Md. : 1997) 2010 Apr;33(3):305-15
Journal of immunotherapy (Hagerstown, Md. : 1997) 2010 Apr;33(3):305-15
Changes in function of HIV-specific T-cell responses with increasing time from infection.
Ndongala ML, Kamya P, Boulet S, Peretz Y, Rouleau D, Tremblay C, Leblanc R, Côté P, Baril JG, Thomas R, Vézina S, Boulassel MR, Routy JP, Sékaly RP, Bernard NF
Viral immunology 2010 Apr;23(2):159-68
Viral immunology 2010 Apr;23(2):159-68
Cellular immunity in children with successful immunoprophylactic treatment for mother-to-child transmission of hepatitis B virus.
Komatsu H, Inui A, Sogo T, Hiejima E, Tateno A, Klenerman P, Fujisawa T
BMC infectious diseases 2010 Apr 28;10:103
BMC infectious diseases 2010 Apr 28;10:103
Rapid progressing allele HLA-B35 Px restricted anti-HIV-1 CD8+ T cells recognize vestigial CTL epitopes.
Willberg CB, Garrison KE, Jones RB, Meiklejohn DA, Spotts G, Liegler TJ, Ostrowski MA, Karlsson AC, Hecht FM, Nixon DF
PloS one 2010 Apr 21;5(4):e10249
PloS one 2010 Apr 21;5(4):e10249
MHC class I molecules with Superenhanced CD8 binding properties bypass the requirement for cognate TCR recognition and nonspecifically activate CTLs.
Wooldridge L, Clement M, Lissina A, Edwards ES, Ladell K, Ekeruche J, Hewitt RE, Laugel B, Gostick E, Cole DK, Debets R, Berrevoets C, Miles JJ, Burrows SR, Price DA, Sewell AK
Journal of immunology (Baltimore, Md. : 1950) 2010 Apr 1;184(7):3357-66
Journal of immunology (Baltimore, Md. : 1950) 2010 Apr 1;184(7):3357-66
Phase 1/2a study of the malaria vaccine candidate apical membrane antigen-1 (AMA-1) administered in adjuvant system AS01B or AS02A.
Spring MD, Cummings JF, Ockenhouse CF, Dutta S, Reidler R, Angov E, Bergmann-Leitner E, Stewart VA, Bittner S, Juompan L, Kortepeter MG, Nielsen R, Krzych U, Tierney E, Ware LA, Dowler M, Hermsen CC, Sauerwein RW, de Vlas SJ, Ofori-Anyinam O, Lanar DE, Williams JL, Kester KE, Tucker K, Shi M, Malkin E, Long C, Diggs CL, Soisson L, Dubois MC, Ballou WR, Cohen J, Heppner DG Jr
PloS one 2009;4(4):e5254
PloS one 2009;4(4):e5254
Immunodominant HIV-1 Cd4+ T cell epitopes in chronic untreated clade C HIV-1 infection.
Ramduth D, Day CL, Thobakgale CF, Mkhwanazi NP, de Pierres C, Reddy S, van der Stok M, Mncube Z, Nair K, Moodley ES, Kaufmann DE, Streeck H, Coovadia HM, Kiepiela P, Goulder PJ, Walker BD
PloS one 2009;4(4):e5013
PloS one 2009;4(4):e5013
A-kinase anchoring in dendritic cells is required for antigen presentation.
Schillace RV, Miller CL, Pisenti N, Grotzke JE, Swarbrick GM, Lewinsohn DM, Carr DW
PloS one 2009;4(3):e4807
PloS one 2009;4(3):e4807
Fludarabine modulates immune response and extends in vivo survival of adoptively transferred CD8 T cells in patients with metastatic melanoma.
Wallen H, Thompson JA, Reilly JZ, Rodmyre RM, Cao J, Yee C
PloS one 2009;4(3):e4749
PloS one 2009;4(3):e4749
Effect of methotrexate and anti-TNF on Epstein-Barr virus T-cell response and viral load in patients with rheumatoid arthritis or spondylarthropathies.
Miceli-Richard C, Gestermann N, Amiel C, Sellam J, Ittah M, Pavy S, Urrutia A, Girauld I, Carcelain G, Venet A, Mariette X
Arthritis research & therapy 2009;11(3):R77
Arthritis research & therapy 2009;11(3):R77
Human immunodeficiency virus type 1 escapes from interleukin-2-producing CD4+ T-cell responses without high-frequency fixation of mutations.
Jones RB, Yue FY, Gu XX, Hunter DV, Mujib S, Gyenes G, Mason RD, Mohamed R, MacDonald KS, Kovacs C, Ostrowski MA
Journal of virology 2009 Sep;83(17):8722-32
Journal of virology 2009 Sep;83(17):8722-32
Maternal transmission of human immunodeficiency virus escape mutations subverts HLA-B57 immunodominance but facilitates viral control in the haploidentical infant.
Schneidewind A, Tang Y, Brockman MA, Ryland EG, Dunkley-Thompson J, Steel-Duncan JC, St John MA, Conrad JA, Kalams SA, Noel F, Allen TM, Christie CD, Feeney ME
Journal of virology 2009 Sep;83(17):8616-27
Journal of virology 2009 Sep;83(17):8616-27
Curcumin induces proapoptotic effects against human melanoma cells and modulates the cellular response to immunotherapeutic cytokines.
Bill MA, Bakan C, Benson DM Jr, Fuchs J, Young G, Lesinski GB
Molecular cancer therapeutics 2009 Sep;8(9):2726-35
Molecular cancer therapeutics 2009 Sep;8(9):2726-35
HLA-A01-, -A03-, and -A024-binding nanomeric epitopes in polyomavirus BK large T antigen.
Ramaswami B, Popescu I, Macedo C, Metes D, Bueno M, Zeevi A, Shapiro R, Viscidi R, Randhawa PS
Human immunology 2009 Sep;70(9):722-8
Human immunology 2009 Sep;70(9):722-8
Genome-wide screening of human T-cell epitopes in influenza A virus reveals a broad spectrum of CD4(+) T-cell responses to internal proteins, hemagglutinins, and neuraminidases.
Babon JA, Cruz J, Orphin L, Pazoles P, Co MD, Ennis FA, Terajima M
Human immunology 2009 Sep;70(9):711-21
Human immunology 2009 Sep;70(9):711-21
CD4+ T cell responses to HLA-DP5-restricted wild-type sequence p53 peptides in patients with head and neck cancer.
Chikamatsu K, Sakakura K, Takahashi G, Okamoto A, Furuya N, Whiteside TL, DeLeo AB, Masuyama K
Cancer immunology, immunotherapy : CII 2009 Sep;58(9):1441-8
Cancer immunology, immunotherapy : CII 2009 Sep;58(9):1441-8
Genetic modification of T cells with IL-21 enhances antigen presentation and generation of central memory tumor-specific cytotoxic T-lymphocytes.
Kaka AS, Shaffer DR, Hartmaier R, Leen AM, Lu A, Bear A, Rooney CM, Foster AE
Journal of immunotherapy (Hagerstown, Md. : 1997) 2009 Sep;32(7):726-36
Journal of immunotherapy (Hagerstown, Md. : 1997) 2009 Sep;32(7):726-36
PD1 blockade reverses the suppression of melanoma antigen-specific CTL by CD4+ CD25(Hi) regulatory T cells.
Wang W, Lau R, Yu D, Zhu W, Korman A, Weber J
International immunology 2009 Sep;21(9):1065-77
International immunology 2009 Sep;21(9):1065-77
Functional effector memory T cells enrich the peritoneal cavity of patients treated with peritoneal dialysis.
Roberts GW, Baird D, Gallagher K, Jones RE, Pepper CJ, Williams JD, Topley N
Journal of the American Society of Nephrology : JASN 2009 Sep;20(9):1895-900
Journal of the American Society of Nephrology : JASN 2009 Sep;20(9):1895-900
Optimization of vaccine responses with an E1, E2b and E3-deleted Ad5 vector circumvents pre-existing anti-vector immunity.
Osada T, Yang XY, Hartman ZC, Glass O, Hodges BL, Niedzwiecki D, Morse MA, Lyerly HK, Amalfitano A, Clay TM
Cancer gene therapy 2009 Sep;16(9):673-82
Cancer gene therapy 2009 Sep;16(9):673-82
The relationship between human effector and memory T cells measured by ex vivo and cultured ELISPOT following recent and distal priming.
Todryk SM, Pathan AA, Keating S, Porter DW, Berthoud T, Thompson F, Klenerman P, Hill AV
Immunology 2009 Sep;128(1):83-91
Immunology 2009 Sep;128(1):83-91
Tumor-derived microvesicles promote regulatory T cell expansion and induce apoptosis in tumor-reactive activated CD8+ T lymphocytes.
Wieckowski EU, Visus C, Szajnik M, Szczepanski MJ, Storkus WJ, Whiteside TL
Journal of immunology (Baltimore, Md. : 1950) 2009 Sep 15;183(6):3720-30
Journal of immunology (Baltimore, Md. : 1950) 2009 Sep 15;183(6):3720-30
Epitope mapping of HIV-specific CD8+ T cells in a cohort dominated by clade A1 infection.
McKinnon LR, Mao X, Kimani J, Wachihi C, Semeniuk C, Mendoza M, Liang B, Luo M, Fowke KR, Plummer FA, Ball TB
PloS one 2009 Sep 11;4(9):e6965
PloS one 2009 Sep 11;4(9):e6965
In silico-accelerated identification of conserved and immunogenic variola/vaccinia T-cell epitopes.
Moise L, McMurry JA, Buus S, Frey S, Martin WD, De Groot AS
Vaccine 2009 Oct 30;27(46):6471-9
Vaccine 2009 Oct 30;27(46):6471-9
Non-redundant role for IL-12 and IL-27 in modulating Th2 polarization of carcinoembryonic antigen specific CD4 T cells from pancreatic cancer patients.
Tassi E, Braga M, Longhi R, Gavazzi F, Parmiani G, Di Carlo V, Protti MP
PloS one 2009 Oct 2;4(10):e7234
PloS one 2009 Oct 2;4(10):e7234
Quantitating T cell cross-reactivity for unrelated peptide antigens.
Ishizuka J, Grebe K, Shenderov E, Peters B, Chen Q, Peng Y, Wang L, Dong T, Pasquetto V, Oseroff C, Sidney J, Hickman H, Cerundolo V, Sette A, Bennink JR, McMichael A, Yewdell JW
Journal of immunology (Baltimore, Md. : 1950) 2009 Oct 1;183(7):4337-45
Journal of immunology (Baltimore, Md. : 1950) 2009 Oct 1;183(7):4337-45
Cytotoxic T lymphocyte therapy with donor T cells prevents and treats adenovirus and Epstein-Barr virus infections after haploidentical and matched unrelated stem cell transplantation.
Leen AM, Christin A, Myers GD, Liu H, Cruz CR, Hanley PJ, Kennedy-Nasser AA, Leung KS, Gee AP, Krance RA, Brenner MK, Heslop HE, Rooney CM, Bollard CM
Blood 2009 Nov 5;114(19):4283-92
Blood 2009 Nov 5;114(19):4283-92
Integrating in silico and in vitro analysis of peptide binding affinity to HLA-Cw*0102: a bioinformatic approach to the prediction of new epitopes.
Walshe VA, Hattotuwagama CK, Doytchinova IA, Wong M, Macdonald IK, Mulder A, Claas FH, Pellegrino P, Turner J, Williams I, Turnbull EL, Borrow P, Flower DR
PloS one 2009 Nov 30;4(11):e8095
PloS one 2009 Nov 30;4(11):e8095
Generation of Epstein-Barr virus-specific cytotoxic T lymphocytes resistant to the immunosuppressive drug tacrolimus (FK506).
De Angelis B, Dotti G, Quintarelli C, Huye LE, Zhang L, Zhang M, Pane F, Heslop HE, Brenner MK, Rooney CM, Savoldo B
Blood 2009 Nov 26;114(23):4784-91
Blood 2009 Nov 26;114(23):4784-91
Identification of major factors influencing ELISpot-based monitoring of cellular responses to antigens from Mycobacterium tuberculosis.
Smith SG, Joosten SA, Verscheure V, Pathan AA, McShane H, Ottenhoff TH, Dockrell HM, Mascart F
PloS one 2009 Nov 24;4(11):e7972
PloS one 2009 Nov 24;4(11):e7972
Ex vivo expansion of tumor specific lymphocytes with IL-15 and IL-21 for adoptive immunotherapy in melanoma.
Huarte E, Fisher J, Turk MJ, Mellinger D, Foster C, Wolf B, Meehan KR, Fadul CE, Ernstoff MS
Cancer letters 2009 Nov 18;285(1):80-8
Cancer letters 2009 Nov 18;285(1):80-8
Human follicular lymphoma CD39+-infiltrating T cells contribute to adenosine-mediated T cell hyporesponsiveness.
Hilchey SP, Kobie JJ, Cochran MR, Secor-Socha S, Wang JC, Hyrien O, Burack WR, Mosmann TR, Quataert SA, Bernstein SH
Journal of immunology (Baltimore, Md. : 1950) 2009 Nov 15;183(10):6157-66
Journal of immunology (Baltimore, Md. : 1950) 2009 Nov 15;183(10):6157-66
Functional properties and epitope characteristics of T-cells recognizing natural HIV-1 variants.
Malhotra U, Nolin J, Horton H, Li F, Corey L, Mullins JI, McElrath MJ
Vaccine 2009 Nov 12;27(48):6678-87
Vaccine 2009 Nov 12;27(48):6678-87
Decreased T cell reactivity to Epstein-Barr virus infected lymphoblastoid cell lines in multiple sclerosis.
Pender MP, Csurhes PA, Lenarczyk A, Pfluger CM, Burrows SR
Journal of neurology, neurosurgery, and psychiatry 2009 May;80(5):498-505
Journal of neurology, neurosurgery, and psychiatry 2009 May;80(5):498-505
Cholera caused by Vibrio cholerae O1 induces T-cell responses in the circulation.
Bhuiyan TR, Lundin SB, Khan AI, Lundgren A, Harris JB, Calderwood SB, Qadri F
Infection and immunity 2009 May;77(5):1888-93
Infection and immunity 2009 May;77(5):1888-93
Cell-mediated immune responses to human papillomavirus 16 E6 and E7 antigens as measured by interferon gamma enzyme-linked immunospot in women with cleared or persistent human papillomavirus infection.
Farhat S, Nakagawa M, Moscicki AB
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 2009 May;19(4):508-12
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 2009 May;19(4):508-12
Automation of the ELISpot assay for high-throughput detection of antigen-specific T-cell responses.
Almeida CA, Roberts SG, Laird R, McKinnon E, Ahmed I, Pfafferott K, Turley J, Keane NM, Lucas A, Rushton B, Chopra A, Mallal S, John M
Journal of immunological methods 2009 May 15;344(1):1-5
Journal of immunological methods 2009 May 15;344(1):1-5
Detection of tuberculosis in HIV-infected children using an enzyme-linked immunospot assay.
Davies MA, Connell T, Johannisen C, Wood K, Pienaar S, Wilkinson KA, Wilkinson RJ, Zar HJ, Eley B, Beatty D, Curtis N, Nicol MP
AIDS (London, England) 2009 May 15;23(8):961-969
AIDS (London, England) 2009 May 15;23(8):961-969
Host immune responses to chronic adenovirus infections in human and nonhuman primates.
Calcedo R, Vandenberghe LH, Roy S, Somanathan S, Wang L, Wilson JM
Journal of virology 2009 Mar;83(6):2623-31
Journal of virology 2009 Mar;83(6):2623-31
Decreased EBNA-1-specific CD8+ T cells in patients with Epstein-Barr virus-associated nasopharyngeal carcinoma.
Fogg MH, Wirth LJ, Posner M, Wang F
Proceedings of the National Academy of Sciences of the United States of America 2009 Mar 3;106(9):3318-23
Proceedings of the National Academy of Sciences of the United States of America 2009 Mar 3;106(9):3318-23
HV-1-specific cytotoxic T lymphocytes and breast milk HIV-1 transmission.
John-Stewart GC, Mbori-Ngacha D, Payne BL, Farquhar C, Richardson BA, Emery S, Otieno P, Obimbo E, Dong T, Slyker J, Nduati R, Overbaugh J, Rowland-Jones S
The Journal of infectious diseases 2009 Mar 15;199(6):889-98
The Journal of infectious diseases 2009 Mar 15;199(6):889-98
ESAT-6 inhibits production of IFN-gamma by Mycobacterium tuberculosis-responsive human T cells.
Wang X, Barnes PF, Dobos-Elder KM, Townsend JC, Chung YT, Shams H, Weis SE, Samten B
Journal of immunology (Baltimore, Md. : 1950) 2009 Mar 15;182(6):3668-77
Journal of immunology (Baltimore, Md. : 1950) 2009 Mar 15;182(6):3668-77
MHC class I/peptide transfer between dendritic cells overcomes poor cross-presentation by monocyte-derived APCs that engulf dying cells.
Qu C, Nguyen VA, Merad M, Randolph GJ
Journal of immunology (Baltimore, Md. : 1950) 2009 Mar 15;182(6):3650-9
Journal of immunology (Baltimore, Md. : 1950) 2009 Mar 15;182(6):3650-9
NY-ESO-1 DNA vaccine induces T-cell responses that are suppressed by regulatory T cells.
Gnjatic S, Altorki NK, Tang DN, Tu SM, Kundra V, Ritter G, Old LJ, Logothetis CJ, Sharma P
Clinical cancer research : an official journal of the American Association for Cancer Research 2009 Mar 15;15(6):2130-9
Clinical cancer research : an official journal of the American Association for Cancer Research 2009 Mar 15;15(6):2130-9
Enhancing the in vivo expansion of adoptively transferred EBV-specific CTL with lymphodepleting CD45 monoclonal antibodies in NPC patients.
Louis CU, Straathof K, Bollard CM, Gerken C, Huls MH, Gresik MV, Wu MF, Weiss HL, Gee AP, Brenner MK, Rooney CM, Heslop HE, Gottschalk S
Blood 2009 Mar 12;113(11):2442-50
Blood 2009 Mar 12;113(11):2442-50
Reversal of human papillomavirus-specific T cell immune suppression through TLR agonist treatment of Langerhans cells exposed to human papillomavirus type 16.
Fahey LM, Raff AB, Da Silva DM, Kast WM
Journal of immunology (Baltimore, Md. : 1950) 2009 Mar 1;182(5):2919-28
Journal of immunology (Baltimore, Md. : 1950) 2009 Mar 1;182(5):2919-28
Cytokine profiles and antibody responses to Plasmodium falciparum malaria infection in individuals living in Ibadan, southwest Nigeria.
Iriemenam NC, Okafor CM, Balogun HA, Ayede I, Omosun Y, Persson JO, Hagstedt M, Anumudu CI, Nwuba RI, Troye-Blomberg M, Berzins K
African health sciences 2009 Jun;9(2):66-74
African health sciences 2009 Jun;9(2):66-74
Maturation pathways of dendritic cells determine TAP1 and TAP2 levels and cross-presenting function.
López-Albaitero A, Mailliard R, Hackman T, Andrade Filho PA, Wang X, Gooding W, Ferrone S, Kalinski P, Ferris RL
Journal of immunotherapy (Hagerstown, Md. : 1997) 2009 Jun;32(5):465-73
Journal of immunotherapy (Hagerstown, Md. : 1997) 2009 Jun;32(5):465-73
Interleukin-12 is the optimum cytokine to expand human Th17 cells in vitro.
Nady S, Ignatz-Hoover J, Shata MT
Clinical and vaccine immunology : CVI 2009 Jun;16(6):798-805
Clinical and vaccine immunology : CVI 2009 Jun;16(6):798-805
Identification of C-glycoside analogues that display a potent biological activity against murine and human invariant natural killer T cells.
Li X, Chen G, Garcia-Navarro R, Franck RW, Tsuji M
Immunology 2009 Jun;127(2):216-225
Immunology 2009 Jun;127(2):216-225
CD1c bypasses lysosomes to present a lipopeptide antigen with 12 amino acids.
Van Rhijn I, Young DC, De Jong A, Vazquez J, Cheng TY, Talekar R, Barral DC, León L, Brenner MB, Katz JT, Riese R, Ruprecht RM, O'Connor PB, Costello CE, Porcelli SA, Briken V, Moody DB
The Journal of experimental medicine 2009 Jun 8;206(6):1409-22
The Journal of experimental medicine 2009 Jun 8;206(6):1409-22
Human T cell recognition of the blood stage antigen Plasmodium hypoxanthine guanine xanthine phosphoribosyl transferase (HGXPRT) in acute malaria.
Woodberry T, Pinzon-Charry A, Piera KA, Panpisutchai Y, Engwerda CR, Doolan DL, Salwati E, Kenangalem E, Tjitra E, Price RN, Good MF, Anstey NM
Malaria journal 2009 Jun 7;8:122
Malaria journal 2009 Jun 7;8:122
Dynamic interaction between STLV-1 proviral load and T-cell response during chronic infection and after immunosuppression in non-human primates.
Souquière S, Mouinga-Ondemé A, Makuwa M, Hermine O, Kazanji M
PloS one 2009 Jun 25;4(6):e6050
PloS one 2009 Jun 25;4(6):e6050
Programmed death (PD)-1 molecule and its ligand PD-L1 distribution among memory CD4 and CD8 T cell subsets in human immunodeficiency virus-1-infected individuals.
Rosignoli G, Lim CH, Bower M, Gotch F, Imami N
Clinical and experimental immunology 2009 Jul;157(1):90-7
Clinical and experimental immunology 2009 Jul;157(1):90-7
Phenotypic and functional markers for 1alpha,25-dihydroxyvitamin D(3)-modified regulatory dendritic cells.
Pedersen AW, Holmstrøm K, Jensen SS, Fuchs D, Rasmussen S, Kvistborg P, Claesson MH, Zocca MB
Clinical and experimental immunology 2009 Jul;157(1):48-59
Clinical and experimental immunology 2009 Jul;157(1):48-59
Patients with lung cancer and paraneoplastic Hu syndrome harbor HuD-specific type 2 CD8+ T cells.
Roberts WK, Deluca IJ, Thomas A, Fak J, Williams T, Buckley N, Dousmanis AG, Posner JB, Darnell RB
The Journal of clinical investigation 2009 Jul;119(7):2042-51
The Journal of clinical investigation 2009 Jul;119(7):2042-51
Recombinant Modified Vaccinia Ankara (MVA) effectively boosts DNA-primed HIV-specific immune responses in humans despite pre-existing vaccinia immunity.
Gudmundsdotter L, Nilsson C, Brave A, Hejdeman B, Earl P, Moss B, Robb M, Cox J, Michael N, Marovich M, Biberfeld G, Sandström E, Wahren B
Vaccine 2009 Jul 16;27(33):4468-74
Vaccine 2009 Jul 16;27(33):4468-74
Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen.
Johnson LA, Morgan RA, Dudley ME, Cassard L, Yang JC, Hughes MS, Kammula US, Royal RE, Sherry RM, Wunderlich JR, Lee CC, Restifo NP, Schwarz SL, Cogdill AP, Bishop RJ, Kim H, Brewer CC, Rudy SF, VanWaes C, Davis JL, Mathur A, Ripley RT, Nathan DA, Laurencot CM, Rosenberg SA
Blood 2009 Jul 16;114(3):535-46
Blood 2009 Jul 16;114(3):535-46
Enhanced systemic immune reactivity to a Basal cell carcinoma associated antigen following photodynamic therapy.
Kabingu E, Oseroff AR, Wilding GE, Gollnick SO
Clinical cancer research : an official journal of the American Association for Cancer Research 2009 Jul 1;15(13):4460-6
Clinical cancer research : an official journal of the American Association for Cancer Research 2009 Jul 1;15(13):4460-6
Human immunodeficiency virus-specific gamma interferon enzyme-linked immunospot assay responses targeting specific regions of the proteome during primary subtype C infection are poor predictors of the course of viremia and set point.
Gray CM, Mlotshwa M, Riou C, Mathebula T, de Assis Rosa D, Mashishi T, Seoighe C, Ngandu N, van Loggerenberg F, Morris L, Mlisana K, Williamson C, Karim SA, CAPRISA 002 Acute Infection Study Team
Journal of virology 2009 Jan;83(1):470-8
Journal of virology 2009 Jan;83(1):470-8
Human uterine NK cells interact with uterine macrophages via NKG2D upon stimulation with PAMPs.
Basu S, Eriksson M, Pioli PA, Conejo-Garcia J, Mselle TF, Yamamoto S, Wira CR, Sentman CL
American journal of reproductive immunology (New York, N.Y. : 1989) 2009 Jan;61(1):52-61
American journal of reproductive immunology (New York, N.Y. : 1989) 2009 Jan;61(1):52-61
Regulation of antigen presentation machinery in human dendritic cells by recombinant adenovirus.
Vujanovic L, Whiteside TL, Potter DM, Chu J, Ferrone S, Butterfield LH
Cancer immunology, immunotherapy : CII 2009 Jan;58(1):121-33
Cancer immunology, immunotherapy : CII 2009 Jan;58(1):121-33
Hepatitis C virus-specific T-cell immune responses in seronegative injection drug users.
Zeremski M, Shu MA, Brown Q, Wu Y, Des Jarlais DC, Busch MP, Talal AH, Edlin BR
Journal of viral hepatitis 2009 Jan;16(1):10-20
Journal of viral hepatitis 2009 Jan;16(1):10-20
In vitro evidence that commercial influenza vaccines are not similar in their ability to activate human T cell responses.
Co MD, Orphin L, Cruz J, Pazoles P, Green KM, Potts J, Leporati AM, Babon JA, Evans JE, Ennis FA, Terajima M
Vaccine 2009 Jan 7;27(2):319-27
Vaccine 2009 Jan 7;27(2):319-27
MIG (CXCL9) is a more sensitive measure than IFN-gamma of vaccine induced T-cell responses in volunteers receiving investigated malaria vaccines.
Berthoud TK, Dunachie SJ, Todryk S, Hill AV, Fletcher HA
Journal of immunological methods 2009 Jan 1;340(1):33-41
Journal of immunological methods 2009 Jan 1;340(1):33-41
Anti-moesin antibodies in the serum of patients with aplastic anemia stimulate peripheral blood mononuclear cells to secrete TNF-alpha and IFN-gamma.
Takamatsu H, Espinoza JL, Lu X, Qi Z, Okawa K, Nakao S
Journal of immunology (Baltimore, Md. : 1950) 2009 Jan 1;182(1):703-10
Journal of immunology (Baltimore, Md. : 1950) 2009 Jan 1;182(1):703-10
A phase I trial of a human papillomavirus DNA vaccine for HPV16+ cervical intraepithelial neoplasia 2/3.
Trimble CL, Peng S, Kos F, Gravitt P, Viscidi R, Sugar E, Pardoll D, Wu TC
Clinical cancer research : an official journal of the American Association for Cancer Research 2009 Jan 1;15(1):361-7
Clinical cancer research : an official journal of the American Association for Cancer Research 2009 Jan 1;15(1):361-7
Concordant proficiency in measurement of T-cell immunity in human immunodeficiency virus vaccine clinical trials by peripheral blood mononuclear cell and enzyme-linked immunospot assays in laboratories from three continents.
Boaz MJ, Hayes P, Tarragona T, Seamons L, Cooper A, Birungi J, Kitandwe P, Semaganda A, Kaleebu P, Stevens G, Anzala O, Farah B, Ogola S, Indangasi J, Mhlanga P, Van Eeden M, Thakar M, Pujari A, Mishra S, Goonetilleke N, Moore S, Mahmoud A, Sathyamoorthy P, Mahalingam J, Narayanan PR, Ramanathan VD, Cox JH, Dally L, Gill DK, Gilmour J
Clinical and vaccine immunology : CVI 2009 Feb;16(2):147-55
Clinical and vaccine immunology : CVI 2009 Feb;16(2):147-55
Increasing functional avidity of TCR-redirected T cells by removing defined N-glycosylation sites in the TCR constant domain.
Kuball J, Hauptrock B, Malina V, Antunes E, Voss RH, Wolfl M, Strong R, Theobald M, Greenberg PD
The Journal of experimental medicine 2009 Feb 16;206(2):463-75
The Journal of experimental medicine 2009 Feb 16;206(2):463-75
Herpesvirus seropositivity in childhood associates with decreased monocyte-induced NK cell IFN-gamma production.
Saghafian-Hedengren S, Sundström Y, Sohlberg E, Nilsson C, Linde A, Troye-Blomberg M, Berg L, Sverremark-Ekström E
Journal of immunology (Baltimore, Md. : 1950) 2009 Feb 15;182(4):2511-7
Journal of immunology (Baltimore, Md. : 1950) 2009 Feb 15;182(4):2511-7
Frequencies of region of difference 1 antigen-specific but not purified protein derivative-specific gamma interferon-secreting T cells correlate with the presence of tuberculosis disease but do not distinguish recent from remote latent infections.
Hinks TS, Dosanjh DP, Innes JA, Pasvol G, Hackforth S, Varia H, Millington KA, Liu XQ, Bakir M, Soysal A, Davidson RN, Gunatheesan R, Lalvani A
Infection and immunity 2009 Dec;77(12):5486-95
Infection and immunity 2009 Dec;77(12):5486-95
Melanoma-associated antigen expression in lymphangioleiomyomatosis renders tumor cells susceptible to cytotoxic T cells.
Klarquist J, Barfuss A, Kandala S, Reust MJ, Braun RK, Hu J, Dilling DF, McKee MD, Boissy RE, Love RB, Nishimura MI, Le Poole IC
The American journal of pathology 2009 Dec;175(6):2463-72
The American journal of pathology 2009 Dec;175(6):2463-72
Antiviral responses following L-leucyl-L-leucine methyl esther (LLME)-treated lymphocyte infusions: graft-versus-infection without graft-versus-host disease.
Filicko-O'Hara J, Grosso D, Flomenberg PR, Friedman TM, Brunner J, Drobyski W, Ferber A, Kakhniashvili I, Keever-Taylor C, Mookerjee B, Talano JA, Wagner JI, Korngold R, Flomenberg N
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2009 Dec;15(12):1609-19
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2009 Dec;15(12):1609-19
HIV-1 infection impairs the bronchoalveolar T-cell response to mycobacteria.
Kalsdorf B, Scriba TJ, Wood K, Day CL, Dheda K, Dawson R, Hanekom WA, Lange C, Wilkinson RJ
American journal of respiratory and critical care medicine 2009 Dec 15;180(12):1262-70
American journal of respiratory and critical care medicine 2009 Dec 15;180(12):1262-70
Identification of heme oxygenase-1-specific regulatory CD8+ T cells in cancer patients.
Andersen MH, Sørensen RB, Brimnes MK, Svane IM, Becker JC, thor Straten P
The Journal of clinical investigation 2009 Aug;119(8):2245-56
The Journal of clinical investigation 2009 Aug;119(8):2245-56
Identification of a human cyclin D1-derived peptide that induces human cytotoxic CD4 T cells.
Dao T, Korontsvit T, Zakhaleva V, Haro K, Packin J, Scheinberg DA
PloS one 2009 Aug 25;4(8):e6730
PloS one 2009 Aug 25;4(8):e6730
Minor viral and host genetic polymorphisms can dramatically impact the biologic outcome of an epitope-specific CD8 T-cell response.
Geldmacher C, Metzler IS, Tovanabutra S, Asher TE, Gostick E, Ambrozak DR, Petrovas C, Schuetz A, Ngwenyama N, Kijak G, Maboko L, Hoelscher M, McCutchan F, Price DA, Douek DC, Koup RA
Blood 2009 Aug 20;114(8):1553-62
Blood 2009 Aug 20;114(8):1553-62
Distinct roles for FOXP3 and FOXP3 CD4 T cells in regulating cellular immunity to uncomplicated and severe Plasmodium falciparum malaria.
Walther M, Jeffries D, Finney OC, Njie M, Ebonyi A, Deininger S, Lawrence E, Ngwa-Amambua A, Jayasooriya S, Cheeseman IH, Gomez-Escobar N, Okebe J, Conway DJ, Riley EM
PLoS pathogens 2009 Apr;5(4):e1000364
PLoS pathogens 2009 Apr;5(4):e1000364
Activated human gammadelta T cells as stimulators of specific CD8+ T-cell responses to subdominant Epstein Barr virus epitopes: potential for immunotherapy of cancer.
Landmeier S, Altvater B, Pscherer S, Juergens H, Varnholt L, Hansmeier A, Bollard CM, Moosmann A, Bisping G, Rossig C
Journal of immunotherapy (Hagerstown, Md. : 1997) 2009 Apr;32(3):310-21
Journal of immunotherapy (Hagerstown, Md. : 1997) 2009 Apr;32(3):310-21
Multiple T-cell epitopes overlap positively-selected residues in the p1 spacer protein of HIV-1 gag.
Semeniuk CA, McKinnon L, Peters HO, Gubbins M, Mao X, Ball TB, Luo M, Plummer FA
AIDS (London, England) 2009 Apr 27;23(7):771-7
AIDS (London, England) 2009 Apr 27;23(7):771-7
Rituximab immunotherapy results in the induction of a lymphoma idiotype-specific T-cell response in patients with follicular lymphoma: support for a "vaccinal effect" of rituximab.
Hilchey SP, Hyrien O, Mosmann TR, Livingstone AM, Friedberg JW, Young F, Fisher RI, Kelleher RJ Jr, Bankert RB, Bernstein SH
Blood 2009 Apr 16;113(16):3809-12
Blood 2009 Apr 16;113(16):3809-12
Association of HIV-specific and total CD8+ T memory phenotypes in subtype C HIV-1 infection with viral set point.
Burgers WA, Riou C, Mlotshwa M, Maenetje P, de Assis Rosa D, Brenchley J, Mlisana K, Douek DC, Koup R, Roederer M, de Bruyn G, Karim SA, Williamson C, Gray CM, CAPRISA 002 Acute Infection Study Team
Journal of immunology (Baltimore, Md. : 1950) 2009 Apr 15;182(8):4751-61
Journal of immunology (Baltimore, Md. : 1950) 2009 Apr 15;182(8):4751-61
Dendritic cells based immunotherapy of patient with chondrosarcoma--case report.
Tabarkiewicz J, Radej S, Hus I, Wasiak M, Wdowiak P, Giannopoulos K, Piechnik B, Kłos A, Dmoszyńska A, Rolinski J
Folia histochemica et cytobiologica 2008;46(2):165-70
Folia histochemica et cytobiologica 2008;46(2):165-70
Non-natural and photo-reactive amino acids as biochemical probes of immune function.
Gómez-Nuñez M, Haro KJ, Dao T, Chau D, Won A, Escobar-Alvarez S, Zakhaleva V, Korontsvit T, Gin DY, Scheinberg DA
PloS one 2008;3(12):e3938
PloS one 2008;3(12):e3938
Viral load, clinical disease severity and cellular immune responses in primary varicella zoster virus infection in Sri Lanka.
Malavige GN, Jones L, Kamaladasa SD, Wijewickrama A, Seneviratne SL, Black AP, Ogg GS
PloS one 2008;3(11):e3789
PloS one 2008;3(11):e3789
Tumor-infiltrating T cells correlate with NY-ESO-1-specific autoantibodies in ovarian cancer.
Milne K, Barnes RO, Girardin A, Mawer MA, Nesslinger NJ, Ng A, Nielsen JS, Sahota R, Tran E, Webb JR, Wong MQ, Wick DA, Wray A, McMurtrie E, Köbel M, Kalloger SE, Gilks CB, Watson PH, Nelson BH
PloS one 2008;3(10):e3409
PloS one 2008;3(10):e3409
In vitro study of pro-inflammatory and anti-tumour properties of microvesicles from bacterial cell wall of Pantoea agglomerans.
Spiewak R, Dutkiewicz J
Annals of agricultural and environmental medicine : AAEM 2008;15(1):153-61
Annals of agricultural and environmental medicine : AAEM 2008;15(1):153-61
Identification of HLA-A*01- and HLA-A*02-restricted CD8+ T-cell epitopes shared among group B enteroviruses.
Weinzierl AO, Rudolf D, Maurer D, Wernet D, Rammensee HG, Stevanović S, Klingel K
The Journal of general virology 2008 Sep;89(Pt 9):2090-2097
The Journal of general virology 2008 Sep;89(Pt 9):2090-2097
Higher homologous and lower cross-reactive Gag-specific T-cell responses in human immunodeficiency virus type 2 (HIV-2) than in HIV-1 infection.
Jennes W, Camara M, Dièye T, Mboup S, Kestens L
Journal of virology 2008 Sep;82(17):8619-28
Journal of virology 2008 Sep;82(17):8619-28
CD4+ T helper responses in squamous cell carcinoma of the head and neck.
Chikamatsu K, Sakakura K, Yamamoto T, Furuya N, Whiteside TL, Masuyama K
Oral oncology 2008 Sep;44(9):870-7
Oral oncology 2008 Sep;44(9):870-7
Inducing efficient cross-priming using antigen-coated yeast particles.
Howland SW, Tsuji T, Gnjatic S, Ritter G, Old LJ, Wittrup KD
Journal of immunotherapy (Hagerstown, Md. : 1997) 2008 Sep;31(7):607-19
Journal of immunotherapy (Hagerstown, Md. : 1997) 2008 Sep;31(7):607-19
Fiber-modified recombinant adenoviral constructs encoding hepatitis C virus proteins induce potent HCV-specific T cell response.
Thammanichanond D, Moneer S, Yotnda P, Aitken C, Earnest-Silveira L, Jackson D, Hellard M, McCluskey J, Torresi J, Bharadwaj M
Clinical immunology (Orlando, Fla.) 2008 Sep;128(3):329-39
Clinical immunology (Orlando, Fla.) 2008 Sep;128(3):329-39
Pilot study of diagnostic potential of the Mycobacterium tuberculosis recombinant HBHA protein in a vaccinated population in Finland.
Savolainen L, Pusa L, Kim HJ, Sillanpää H, Seppälä I, Tuuminen T
PloS one 2008 Sep 25;3(9):e3272
PloS one 2008 Sep 25;3(9):e3272
IL-15 as memory T-cell adjuvant for topical HIV-1 DermaVir vaccine.
Calarota SA, Dai A, Trocio JN, Weiner DB, Lori F, Lisziewicz J
Vaccine 2008 Sep 19;26(40):5188-95
Vaccine 2008 Sep 19;26(40):5188-95
Expansion of human cytomegalovirus (HCMV) immediate-early 1-specific CD8+ T cells and control of HCMV replication after allogeneic stem cell transplantation.
Sacre K, Nguyen S, Deback C, Carcelain G, Vernant JP, Leblond V, Autran B, Dhedin N
Journal of virology 2008 Oct;82(20):10143-52
Journal of virology 2008 Oct;82(20):10143-52
Activation of autologous leukemia-specific T cells in acute myeloid leukemia: monocyte-derived dendritic cells cocultured with leukemic blasts compared with leukemia-derived dendritic cells.
Draube A, Beyer M, Wolf J
European journal of haematology 2008 Oct;81(4):281-8
European journal of haematology 2008 Oct;81(4):281-8
Increased circulating paternal antigen-specific IFN-gamma- and IL-4-secreting cells during pregnancy in allergic and non-allergic women.
Persson M, Ekerfelt C, Ernerudh J, Matthiesen L, Jenmalm M, Jonsson Y, Sandberg M, Berg G
Journal of reproductive immunology 2008 Oct;79(1):70-8
Journal of reproductive immunology 2008 Oct;79(1):70-8
Studies on mRNA electroporation of immature and mature dendritic cells: effects on their immunogenic potential.
Met O, Eriksen J, Svane IM
Molecular biotechnology 2008 Oct;40(2):151-60
Molecular biotechnology 2008 Oct;40(2):151-60
Immunization with analog peptide in combination with CpG and montanide expands tumor antigen-specific CD8+ T cells in melanoma patients.
Fourcade J, Kudela P, Andrade Filho PA, Janjic B, Land SR, Sander C, Krieg A, Donnenberg A, Shen H, Kirkwood JM, Zarour HM
Journal of immunotherapy (Hagerstown, Md. : 1997) 2008 Oct;31(8):781-91
Journal of immunotherapy (Hagerstown, Md. : 1997) 2008 Oct;31(8):781-91
Treatment of leber congenital amaurosis due to RPE65 mutations by ocular subretinal injection of adeno-associated virus gene vector: short-term results of a phase I trial.
Hauswirth WW, Aleman TS, Kaushal S, Cideciyan AV, Schwartz SB, Wang L, Conlon TJ, Boye SL, Flotte TR, Byrne BJ, Jacobson SG
Human gene therapy 2008 Oct;19(10):979-90
Human gene therapy 2008 Oct;19(10):979-90
The intracellular detection of MIP-1beta enhances the capacity to detect IFN-gamma mediated HIV-1-specific CD8 T-cell responses in a flow cytometric setting providing a sensitive alternative to the ELISPOT.
Kutscher S, Dembek CJ, Allgayer S, Heltai S, Stadlbauer B, Biswas P, Nozza S, Tambussi G, Bogner JR, Stellbrink HJ, Goebel FD, Lusso P, Tinelli M, Poli G, Erfle V, Pohla H, Malnati M, Cosma A
AIDS research and therapy 2008 Oct 6;5:22
AIDS research and therapy 2008 Oct 6;5:22
Effects of recombinant human growth hormone on HIV-1-specific T-cell responses, thymic output and proviral DNA in patients on HAART: 48-week follow-up.
Herasimtschuk AA, Westrop SJ, Moyle GJ, Downey JS, Imami N
Journal of immune based therapies and vaccines 2008 Oct 31;6:7
Journal of immune based therapies and vaccines 2008 Oct 31;6:7
Dynamics of human respiratory virus-specific CD8+ T cell responses in blood and airways during episodes of common cold.
Heidema J, Rossen JW, Lukens MV, Ketel MS, Scheltens E, Kranendonk ME, van Maren WW, van Loon AM, Otten HG, Kimpen JL, van Bleek GM
Journal of immunology (Baltimore, Md. : 1950) 2008 Oct 15;181(8):5551-9
Journal of immunology (Baltimore, Md. : 1950) 2008 Oct 15;181(8):5551-9
T cell responses to whole SARS coronavirus in humans.
Li CK, Wu H, Yan H, Ma S, Wang L, Zhang M, Tang X, Temperton NJ, Weiss RA, Brenchley JM, Douek DC, Mongkolsapaya J, Tran BH, Lin CL, Screaton GR, Hou JL, McMichael AJ, Xu XN
Journal of immunology (Baltimore, Md. : 1950) 2008 Oct 15;181(8):5490-500
Journal of immunology (Baltimore, Md. : 1950) 2008 Oct 15;181(8):5490-500
Generation of HIV-1-specific CD8+ cell responses following allogeneic hematopoietic cell transplantation.
Woolfrey AE, Malhotra U, Harrington RD, McNevin J, Manley TJ, Riddell SR, Coombs RW, Appelbaum FR, Corey L, Storb R
Blood 2008 Oct 15;112(8):3484-7
Blood 2008 Oct 15;112(8):3484-7
Resting regulatory CD4 T cells: a site of HIV persistence in patients on long-term effective antiretroviral therapy.
Tran TA, de Goër de Herve MG, Hendel-Chavez H, Dembele B, Le Névot E, Abbed K, Pallier C, Goujard C, Gasnault J, Delfraissy JF, Balazuc AM, Taoufik Y
PloS one 2008 Oct 1;3(10):e3305
PloS one 2008 Oct 1;3(10):e3305
A comparison of IFNgamma detection methods used in tuberculosis vaccine trials.
Beveridge NE, Fletcher HA, Hughes J, Pathan AA, Scriba TJ, Minassian A, Sander CR, Whelan KT, Dockrell HM, Hill AV, Hanekom WA, McShane H
Tuberculosis (Edinburgh, Scotland) 2008 Nov;88(6):631-40
Tuberculosis (Edinburgh, Scotland) 2008 Nov;88(6):631-40
Host ethnicity and virus genotype shape the hepatitis B virus-specific T-cell repertoire.
Tan AT, Loggi E, Boni C, Chia A, Gehring AJ, Sastry KS, Goh V, Fisicaro P, Andreone P, Brander C, Lim SG, Ferrari C, Bihl F, Bertoletti A
Journal of virology 2008 Nov;82(22):10986-97
Journal of virology 2008 Nov;82(22):10986-97
Enhancement of human immunodeficiency virus (HIV)-specific CD8+ T cells in cerebrospinal fluid compared to those in blood among antiretroviral therapy-naive HIV-positive subjects.
Sadagopal S, Lorey SL, Barnett L, Basham R, Lebo L, Erdem H, Haman K, Avison M, Waddell K, Haas DW, Kalams SA
Journal of virology 2008 Nov;82(21):10418-28
Journal of virology 2008 Nov;82(21):10418-28
Optimizing peptide matrices for identifying T-cell antigens.
Precopio ML, Butterfield TR, Casazza JP, Little SJ, Richman DD, Koup RA, Roederer M
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2008 Nov;73(11):1071-8
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2008 Nov;73(11):1071-8
Urea-mediated cross-presentation of soluble Epstein-Barr virus BZLF1 protein.
Barabas S, Gary R, Bauer T, Lindner J, Lindner P, Weinberger B, Jilg W, Wolf H, Deml L
PLoS pathogens 2008 Nov;4(11):e1000198
PLoS pathogens 2008 Nov;4(11):e1000198
Identification of an immunodominant region of Fel d 1 and characterization of constituent epitopes.
Bateman EA, Ardern-Jones MR, Ogg GS
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2008 Nov;38(11):1760-8
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2008 Nov;38(11):1760-8
Improved cell mediated immune responses after successful re-vaccination of non-responders to the hepatitis B virus surface antigen (HBsAg) vaccine using the combined hepatitis A and B vaccine.
Nyström J, Cardell K, Björnsdottir TB, Fryden A, Hultgren C, Sällberg M
Vaccine 2008 Nov 5;26(47):5967-72
Vaccine 2008 Nov 5;26(47):5967-72
Immunodominant epitopes in herpes simplex virus type 2 glycoprotein D are recognized by CD4 lymphocytes from both HSV-1 and HSV-2 seropositive subjects.
Kim M, Taylor J, Sidney J, Mikloska Z, Bodsworth N, Lagios K, Dunckley H, Byth-Wilson K, Denis M, Finlayson R, Khanna R, Sette A, Cunningham AL
Journal of immunology (Baltimore, Md. : 1950) 2008 Nov 1;181(9):6604-15
Journal of immunology (Baltimore, Md. : 1950) 2008 Nov 1;181(9):6604-15
Functional impairment of cytomegalovirus specific CD8 T cells predicts high-level replication after renal transplantation.
Mattes FM, Vargas A, Kopycinski J, Hainsworth EG, Sweny P, Nebbia G, Bazeos A, Lowdell M, Klenerman P, Phillips RE, Griffiths PD, Emery VC
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2008 May;8(5):990-9
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2008 May;8(5):990-9
Immunogenicity of human mesenchymal stem cells in HLA-class I-restricted T-cell responses against viral or tumor-associated antigens.
Morandi F, Raffaghello L, Bianchi G, Meloni F, Salis A, Millo E, Ferrone S, Barnaba V, Pistoia V
Stem cells (Dayton, Ohio) 2008 May;26(5):1275-87
Stem cells (Dayton, Ohio) 2008 May;26(5):1275-87
A novel, helminth-derived immunostimulant enhances human recall responses to hepatitis C virus and tetanus toxoid and is dependent on CD56+ cells for its action.
MacDonald AJ, Libri NA, Lustigman S, Barker SJ, Whelan MA, Semper AE, Rosenberg WM
Clinical and experimental immunology 2008 May;152(2):265-73
Clinical and experimental immunology 2008 May;152(2):265-73
Antigen load and viral sequence diversification determine the functional profile of HIV-1-specific CD8+ T cells.
Streeck H, Brumme ZL, Anastario M, Cohen KW, Jolin JS, Meier A, Brumme CJ, Rosenberg ES, Alter G, Allen TM, Walker BD, Altfeld M
PLoS medicine 2008 May 6;5(5):e100
PLoS medicine 2008 May 6;5(5):e100
Comprehensive analysis of west nile virus-specific T cell responses in humans.
Lanteri MC, Heitman JW, Owen RE, Busch T, Gefter N, Kiely N, Kamel HT, Tobler LH, Busch MP, Norris PJ
The Journal of infectious diseases 2008 May 1;197(9):1296-306
The Journal of infectious diseases 2008 May 1;197(9):1296-306
Results and harmonization guidelines from two large-scale international Elispot proficiency panels conducted by the Cancer Vaccine Consortium (CVC/SVI).
Janetzki S, Panageas KS, Ben-Porat L, Boyer J, Britten CM, Clay TM, Kalos M, Maecker HT, Romero P, Yuan J, Kast WM, Hoos A, Elispot Proficiency Panel of the CVC Immune Assay Working Group
Cancer immunology, immunotherapy : CII 2008 Mar;57(3):303-15
Cancer immunology, immunotherapy : CII 2008 Mar;57(3):303-15
Regression of human kidney cancer following allogeneic stem cell transplantation is associated with recognition of an HERV-E antigen by T cells.
Takahashi Y, Harashima N, Kajigaya S, Yokoyama H, Cherkasova E, McCoy JP, Hanada K, Mena O, Kurlander R, Tawab A, Srinivasan R, Lundqvist A, Malinzak E, Geller N, Lerman MI, Childs RW
The Journal of clinical investigation 2008 Mar;118(3):1099-109
The Journal of clinical investigation 2008 Mar;118(3):1099-109
Improved diagnostic evaluation of suspected tuberculosis.
Dosanjh DP, Hinks TS, Innes JA, Deeks JJ, Pasvol G, Hackforth S, Varia H, Millington KA, Gunatheesan R, Guyot-Revol V, Lalvani A
Annals of internal medicine 2008 Mar 4;148(5):325-36
Annals of internal medicine 2008 Mar 4;148(5):325-36
Allogeneic granulocyte macrophage colony-stimulating factor-secreting tumor immunotherapy alone or in sequence with cyclophosphamide for metastatic pancreatic cancer: a pilot study of safety, feasibility, and immune activation.
Laheru D, Lutz E, Burke J, Biedrzycki B, Solt S, Onners B, Tartakovsky I, Nemunaitis J, Le D, Sugar E, Hege K, Jaffee E
Clinical cancer research : an official journal of the American Association for Cancer Research 2008 Mar 1;14(5):1455-63
Clinical cancer research : an official journal of the American Association for Cancer Research 2008 Mar 1;14(5):1455-63
Varicella zoster virus glycoprotein E-specific CD4+ T cells show evidence of recent activation and effector differentiation, consistent with frequent exposure to replicative cycle antigens in healthy immune donors.
Malavige GN, Jones L, Black AP, Ogg GS
Clinical and experimental immunology 2008 Jun;152(3):522-31
Clinical and experimental immunology 2008 Jun;152(3):522-31
Clinical phase 1 testing of the safety and immunogenicity of an epitope-based DNA vaccine in human immunodeficiency virus type 1-infected subjects receiving highly active antiretroviral therapy.
Wilson CC, Newman MJ, Livingston BD, MaWhinney S, Forster JE, Scott J, Schooley RT, Benson CA
Clinical and vaccine immunology : CVI 2008 Jun;15(6):986-94
Clinical and vaccine immunology : CVI 2008 Jun;15(6):986-94
Memory T cells specific for novel human papillomavirus type 16 (HPV16) E6 epitopes in women whose HPV16 infection has become undetectable.
Wang X, Moscicki AB, Tsang L, Brockman A, Nakagawa M
Clinical and vaccine immunology : CVI 2008 Jun;15(6):937-45
Clinical and vaccine immunology : CVI 2008 Jun;15(6):937-45
The Src/ABL kinase inhibitor dasatinib (BMS-354825) inhibits function of normal human T-lymphocytes in vitro.
Blake S, Hughes TP, Mayrhofer G, Lyons AB
Clinical immunology (Orlando, Fla.) 2008 Jun;127(3):330-9
Clinical immunology (Orlando, Fla.) 2008 Jun;127(3):330-9
Rapid diagnosis of Mycobacterium tuberculosis meningitis by enumeration of cerebrospinal fluid antigen-specific T-cells.
Thomas MM, Hinks TS, Raghuraman S, Ramalingam N, Ernst M, Nau R, Lange C, Kösters K, Gnanamuthu C, John GT, Marshall B, Lalvani A
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2008 Jun;12(6):651-7
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2008 Jun;12(6):651-7
Identification of immunogenic HLA-B7 "Achilles' heel" epitopes within highly conserved regions of HIV.
De Groot AS, Rivera DS, McMurry JA, Buus S, Martin W
Vaccine 2008 Jun 6;26(24):3059-71
Vaccine 2008 Jun 6;26(24):3059-71
Intrahepatic CD8(+) lymphocyte trapping during tolerance induction using mushroom derived formulations: a possible role for liver in tolerance induction.
Shuvy M, Hershcovici T, Lull-Noguera C, Wichers H, Danay O, Levanon D, Zolotarov L, Ilan Y
World journal of gastroenterology 2008 Jun 28;14(24):3872-8
World journal of gastroenterology 2008 Jun 28;14(24):3872-8
Comparison of alpha-Type-1 polarizing and standard dendritic cell cytokine cocktail for maturation of therapeutic monocyte-derived dendritic cell preparations from cancer patients.
Trepiakas R, Pedersen AE, Met O, Hansen MH, Berntsen A, Svane IM
Vaccine 2008 Jun 2;26(23):2824-32
Vaccine 2008 Jun 2;26(23):2824-32
Treatment of metastatic melanoma with autologous CD4+ T cells against NY-ESO-1.
Hunder NN, Wallen H, Cao J, Hendricks DW, Reilly JZ, Rodmyre R, Jungbluth A, Gnjatic S, Thompson JA, Yee C
The New England journal of medicine 2008 Jun 19;358(25):2698-703
The New England journal of medicine 2008 Jun 19;358(25):2698-703
Development and dynamics of robust T-cell responses to CML under imatinib treatment.
Chen CI, Maecker HT, Lee PP
Blood 2008 Jun 1;111(11):5342-9
Blood 2008 Jun 1;111(11):5342-9
Identification of HLA-A2 restricted T-cell epitopes within the conserved region of the immunoglobulin G heavy-chain in patients with multiple myeloma.
Belle S, Han F, Condomines M, Christensen O, Witzens-Harig M, Kasper B, Kleist C, Terness P, Moos M, Cremer F, Hose D, Ho AD, Goldschmidt H, Klein B, Hundemer M
European journal of haematology 2008 Jul;81(1):26-35
European journal of haematology 2008 Jul;81(1):26-35
Heterosubtypic T-cell responses against avian influenza H5 haemagglutinin are frequently detected in individuals vaccinated against or previously infected with human subtypes of influenza.
Goy K, Von Bibra S, Lewis J, Laurie K, Barr I, Anderson D, Hellard M, Ffrench R
Influenza and other respiratory viruses 2008 Jul;2(4):115-25
Influenza and other respiratory viruses 2008 Jul;2(4):115-25
Evaluation of immune responses to seasonal influenza vaccination in healthy volunteers and in patients after stem cell transplantation.
Avetisyan G, Aschan J, Hassan M, Ljungman P
Transplantation 2008 Jul 27;86(2):257-63
Transplantation 2008 Jul 27;86(2):257-63
CD4-specific designed ankyrin repeat proteins are novel potent HIV entry inhibitors with unique characteristics.
Schweizer A, Rusert P, Berlinger L, Ruprecht CR, Mann A, Corthésy S, Turville SG, Aravantinou M, Fischer M, Robbiani M, Amstutz P, Trkola A
PLoS pathogens 2008 Jul 25;4(7):e1000109
PLoS pathogens 2008 Jul 25;4(7):e1000109
Cross-subtype antibody and cellular immune responses induced by a polyvalent DNA prime-protein boost HIV-1 vaccine in healthy human volunteers.
Wang S, Kennedy JS, West K, Montefiori DC, Coley S, Lawrence J, Shen S, Green S, Rothman AL, Ennis FA, Arthos J, Pal R, Markham P, Lu S
Vaccine 2008 Jul 23;26(31):3947-57
Vaccine 2008 Jul 23;26(31):3947-57
Poor immunogenicity of BCG in helminth infected population is associated with increased in vitro TGF-beta production.
Elias D, Britton S, Aseffa A, Engers H, Akuffo H
Vaccine 2008 Jul 23;26(31):3897-902
Vaccine 2008 Jul 23;26(31):3897-902
Humoral and cellular response to influenza vaccine in HIV-infected children with full viroimmunologic response to antiretroviral therapy.
Viganò A, Zuccotti GV, Pacei M, Erba P, Castelletti E, Giacomet V, Amendola A, Pariani E, Tanzi E, Clerici M
Journal of acquired immune deficiency syndromes (1999) 2008 Jul 1;48(3):289-96
Journal of acquired immune deficiency syndromes (1999) 2008 Jul 1;48(3):289-96
Immunization of malignant melanoma patients with full-length NY-ESO-1 protein using TLR7 agonist imiquimod as vaccine adjuvant.
Adams S, O'Neill DW, Nonaka D, Hardin E, Chiriboga L, Siu K, Cruz CM, Angiulli A, Angiulli F, Ritter E, Holman RM, Shapiro RL, Berman RS, Berner N, Shao Y, Manches O, Pan L, Venhaus RR, Hoffman EW, Jungbluth A, Gnjatic S, Old L, Pavlick AC, Bhardwaj N
Journal of immunology (Baltimore, Md. : 1950) 2008 Jul 1;181(1):776-84
Journal of immunology (Baltimore, Md. : 1950) 2008 Jul 1;181(1):776-84
Hepatitis B virus e antigen loss during adefovir dipivoxil therapy is associated with enhanced virus-specific CD4+ T-cell reactivity.
Cooksley H, Chokshi S, Maayan Y, Wedemeyer H, Andreone P, Gilson R, Warnes T, Paganin S, Zoulim F, Frederick D, Neumann AU, Brosgart CL, Naoumov NV
Antimicrobial agents and chemotherapy 2008 Jan;52(1):312-20
Antimicrobial agents and chemotherapy 2008 Jan;52(1):312-20
The lipophilic hapten parthenolide induces interferon-gamma and interleukin-13 production by peripheral blood-derived CD8+ T cells from contact allergic subjects in vitro.
Wahlkvist H, Masjedi K, Gruvberger B, Zuber B, Karlberg AT, Bruze M, Ahlborg N
The British journal of dermatology 2008 Jan;158(1):70-7
The British journal of dermatology 2008 Jan;158(1):70-7
Therapeutic vaccination with a trivalent T-cell receptor (TCR) peptide vaccine restores deficient FoxP3 expression and TCR recognition in subjects with multiple sclerosis.
Vandenbark AA, Culbertson NE, Bartholomew RM, Huan J, Agotsch M, LaTocha D, Yadav V, Mass M, Whitham R, Lovera J, Milano J, Theofan G, Chou YK, Offner H, Bourdette DN
Immunology 2008 Jan;123(1):66-78
Immunology 2008 Jan;123(1):66-78
A phase I clinical study of vaccination of melanoma patients with dendritic cells loaded with allogeneic apoptotic/necrotic melanoma cells. Analysis of toxicity and immune response to the vaccine and of IL-10 -1082 promoter genotype as predictor of disease progression.
von Euw EM, Barrio MM, Furman D, Levy EM, Bianchini M, Peguillet I, Lantz O, Vellice A, Kohan A, Chacón M, Yee C, Wainstok R, Mordoh J
Journal of translational medicine 2008 Jan 25;6:6
Journal of translational medicine 2008 Jan 25;6:6
Increased antigen presentation efficiency by coupling antigens to MHC class I trafficking signals.
Kreiter S, Selmi A, Diken M, Sebastian M, Osterloh P, Schild H, Huber C, Türeci O, Sahin U
Journal of immunology (Baltimore, Md. : 1950) 2008 Jan 1;180(1):309-18
Journal of immunology (Baltimore, Md. : 1950) 2008 Jan 1;180(1):309-18
Induction of tumor-specific CD4+ and CD8+ T-cell immunity in cervical cancer patients by a human papillomavirus type 16 E6 and E7 long peptides vaccine.
Welters MJ, Kenter GG, Piersma SJ, Vloon AP, Löwik MJ, Berends-van der Meer DM, Drijfhout JW, Valentijn AR, Wafelman AR, Oostendorp J, Fleuren GJ, Offringa R, Melief CJ, van der Burg SH
Clinical cancer research : an official journal of the American Association for Cancer Research 2008 Jan 1;14(1):178-87
Clinical cancer research : an official journal of the American Association for Cancer Research 2008 Jan 1;14(1):178-87
Mannose-capped lipoarabinomannan- and prostaglandin E2-dependent expansion of regulatory T cells in human Mycobacterium tuberculosis infection.
Garg A, Barnes PF, Roy S, Quiroga MF, Wu S, García VE, Krutzik SR, Weis SE, Vankayalapati R
European journal of immunology 2008 Feb;38(2):459-69
European journal of immunology 2008 Feb;38(2):459-69
Peptide impurities in commercial synthetic peptides and their implications for vaccine trial assessment.
Currier JR, Galley LM, Wenschuh H, Morafo V, Ratto-Kim S, Gray CM, Maboko L, Hoelscher M, Marovich MA, Cox JH
Clinical and vaccine immunology : CVI 2008 Feb;15(2):267-76
Clinical and vaccine immunology : CVI 2008 Feb;15(2):267-76
Tonsilar NK cells restrict B cell transformation by the Epstein-Barr virus via IFN-gamma.
Strowig T, Brilot F, Arrey F, Bougras G, Thomas D, Muller WA, Münz C
PLoS pathogens 2008 Feb 8;4(2):e27
PLoS pathogens 2008 Feb 8;4(2):e27
Cross-subtype antibody and cellular immune responses induced by a polyvalent DNA prime-protein boost HIV-1 vaccine in healthy human volunteers.
Wang S, Kennedy JS, West K, Montefiori DC, Coley S, Lawrence J, Shen S, Green S, Rothman AL, Ennis FA, Arthos J, Pal R, Markham P, Lu S
Vaccine 2008 Feb 20;26(8):1098-110
Vaccine 2008 Feb 20;26(8):1098-110
Major histocompatibility complex class I cytotoxic T lymphocyte immunity to human metapneumovirus (hMPV) in individuals with previous hMPV infection and respiratory disease.
Herd KA, Nissen MD, Hopkins PM, Sloots TP, Tindle RW
The Journal of infectious diseases 2008 Feb 15;197(4):584-92
The Journal of infectious diseases 2008 Feb 15;197(4):584-92
Induction of regulatory T cell-resistant helper CD4+ T cells by bacterial vector.
Nishikawa H, Tsuji T, Jäger E, Briones G, Ritter G, Old LJ, Galán JE, Shiku H, Gnjatic S
Blood 2008 Feb 1;111(3):1404-12
Blood 2008 Feb 1;111(3):1404-12
Vaccinia virus-specific CD8(+) T-cell responses target a group of epitopes without a strong immunodominance hierarchy in humans.
Terajima M, Orphin L, Leporati AM, Pazoles P, Cruz J, Rothman AL, Ennis FA
Human immunology 2008 Dec;69(12):815-25
Human immunology 2008 Dec;69(12):815-25
RhoC a new target for therapeutic vaccination against metastatic cancer.
Wenandy L, Sørensen RB, Svane IM, Thor Straten P, Andersen MH
Cancer immunology, immunotherapy : CII 2008 Dec;57(12):1871-8
Cancer immunology, immunotherapy : CII 2008 Dec;57(12):1871-8
Lack of an inverse association between tuberculosis infection and atopy: by T-cell-based immune assay (RD1-ELISpot).
Soysal A, Bahçeciler N, Barlan I, Bakir M
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 2008 Dec;19(8):709-15
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 2008 Dec;19(8):709-15
Evaluation of antigen-specific T-cell responses with a miniaturized and automated method.
Li Pira G, Ivaldi F, Dentone C, Righi E, Del Bono V, Viscoli C, Koopman G, Manca F
Clinical and vaccine immunology : CVI 2008 Dec;15(12):1811-8
Clinical and vaccine immunology : CVI 2008 Dec;15(12):1811-8
Safety and immunogenicity of recombinant poxvirus HIV-1 vaccines in young adults on highly active antiretroviral therapy.
Greenough TC, Cunningham CK, Muresan P, McManus M, Persaud D, Fenton T, Barker P, Gaur A, Panicali D, Sullivan JL, Luzuriaga K, Pediatric AIDS Clinical Trials Group P1059 Team
Vaccine 2008 Dec 9;26(52):6883-93
Vaccine 2008 Dec 9;26(52):6883-93
Lessons from IAVI-006, a phase I clinical trial to evaluate the safety and immunogenicity of the pTHr.HIVA DNA and MVA.HIVA vaccines in a prime-boost strategy to induce HIV-1 specific T-cell responses in healthy volunteers.
Guimarães-Walker A, Mackie N, McCormack S, Hanke T, Schmidt C, Gilmour J, Barin B, McMichael A, Weber J, Legg K, Babiker A, Hayes P, Gotch F, Smith C, Dally L, Dorrell L, Cebere I, Kay R, Winstone N, Moore S, Goonetilleke N, Fast P, IAVI-006 Study Group
Vaccine 2008 Dec 2;26(51):6671-7
Vaccine 2008 Dec 2;26(51):6671-7
Naturally acquired humoral and cellular immune responses to Plasmodium vivax merozoite surface protein 9 in Northwestern Amazon individuals.
Lima-Junior JC, Tran TM, Meyer EV, Singh B, De-Simone SG, Santos F, Daniel-Ribeiro CT, Moreno A, Barnwell JW, Galinski MR, Oliveira-Ferreira J
Vaccine 2008 Dec 2;26(51):6645-54
Vaccine 2008 Dec 2;26(51):6645-54
T cell responses to mycobacterial catalase-peroxidase profile a pathogenic antigen in systemic sarcoidosis.
Chen ES, Wahlström J, Song Z, Willett MH, Wikén M, Yung RC, West EE, McDyer JF, Zhang Y, Eklund A, Grunewald J, Moller DR
Journal of immunology (Baltimore, Md. : 1950) 2008 Dec 15;181(12):8784-96
Journal of immunology (Baltimore, Md. : 1950) 2008 Dec 15;181(12):8784-96
Transduction with the antioxidant enzyme catalase protects human T cells against oxidative stress.
Ando T, Mimura K, Johansson CC, Hanson MG, Mougiakakos D, Larsson C, Martins da Palma T, Sakurai D, Norell H, Li M, Nishimura MI, Kiessling R
Journal of immunology (Baltimore, Md. : 1950) 2008 Dec 15;181(12):8382-90
Journal of immunology (Baltimore, Md. : 1950) 2008 Dec 15;181(12):8382-90
Mechanisms of HIV non-progression; robust and sustained CD4+ T-cell proliferative responses to p24 antigen correlate with control of viraemia and lack of disease progression after long-term transfusion-acquired HIV-1 infection.
Dyer WB, Zaunders JJ, Yuan FF, Wang B, Learmont JC, Geczy AF, Saksena NK, McPhee DA, Gorry PR, Sullivan JS
Retrovirology 2008 Dec 11;5:112
Retrovirology 2008 Dec 11;5:112
Nadir CD4 T-cell counts continue to influence interferon-gamma responses in HIV patients who began antiretroviral treatment with advanced immunodeficiency.
Price P, Fernandez S, Tan DB, James IR, Keane NM, French MA
Journal of acquired immune deficiency syndromes (1999) 2008 Dec 1;49(4):462-4
Journal of acquired immune deficiency syndromes (1999) 2008 Dec 1;49(4):462-4
CD4+ T helper cell responses against human bocavirus viral protein 2 viruslike particles in healthy adults.
Lindner J, Zehentmeier S, Franssila R, Barabas S, Schroeder J, Deml L, Modrow S
The Journal of infectious diseases 2008 Dec 1;198(11):1677-84
The Journal of infectious diseases 2008 Dec 1;198(11):1677-84
Deficiency of HIV-Gag-specific T cells in early childhood correlates with poor viral containment.
Huang S, Dunkley-Thompson J, Tang Y, Macklin EA, Steel-Duncan J, Singh-Minott I, Ryland EG, Smikle M, Walker BD, Christie CD, Feeney ME
Journal of immunology (Baltimore, Md. : 1950) 2008 Dec 1;181(11):8103-11
Journal of immunology (Baltimore, Md. : 1950) 2008 Dec 1;181(11):8103-11
Transmission of human immunodeficiency virus type 1 from a patient who developed AIDS to an elite suppressor.
Bailey JR, O'Connell K, Yang HC, Han Y, Xu J, Jilek B, Williams TM, Ray SC, Siliciano RF, Blankson JN
Journal of virology 2008 Aug;82(15):7395-410
Journal of virology 2008 Aug;82(15):7395-410
Analysis of the cellular immune response in patients with the digestive and indeterminate forms of Chagas' disease.
Ribeiro BM, Crema E, Rodrigues V Jr
Human immunology 2008 Aug;69(8):484-9
Human immunology 2008 Aug;69(8):484-9
Recognition of naturally processed and ovarian cancer reactive CD8+ T cell epitopes within a promiscuous HLA class II T-helper region of NY-ESO-1.
Matsuzaki J, Qian F, Luescher I, Lele S, Ritter G, Shrikant PA, Gnjatic S, Old LJ, Odunsi K
Cancer immunology, immunotherapy : CII 2008 Aug;57(8):1185-95
Cancer immunology, immunotherapy : CII 2008 Aug;57(8):1185-95
Immunologic response to primary cryoablation of high-risk prostate cancer.
Si T, Guo Z, Hao X
Cryobiology 2008 Aug;57(1):66-71
Cryobiology 2008 Aug;57(1):66-71
Leishmania surface protein gp63 binds directly to human natural killer cells and inhibits proliferation.
Lieke T, Nylén S, Eidsmo L, McMaster WR, Mohammadi AM, Khamesipour A, Berg L, Akuffo H
Clinical and experimental immunology 2008 Aug;153(2):221-30
Clinical and experimental immunology 2008 Aug;153(2):221-30
Influenza virus vaccination induces interleukin-12/23 receptor beta 1 (IL-12/23R beta 1)-independent production of gamma interferon (IFN-gamma) and humoral immunity in patients with genetic deficiencies in IL-12/23R beta 1 or IFN-gamma receptor I.
de Boer T, van Dissel JT, Kuijpers TW, Rimmelzwaan GF, Kroon FP, Ottenhoff TH
Clinical and vaccine immunology : CVI 2008 Aug;15(8):1171-5
Clinical and vaccine immunology : CVI 2008 Aug;15(8):1171-5
The number and function of circulating dendritic cells may limit effector memory CD4+ T-cell responses in HIV patients responding to antiretroviral therapy.
Fernandez S, Stone SF, Price P, French MA
Clinical immunology (Orlando, Fla.) 2008 Aug;128(2):228-37
Clinical immunology (Orlando, Fla.) 2008 Aug;128(2):228-37
Maintenance of large subpopulations of differentiated CD8 T-cells two years after cytomegalovirus infection in Gambian infants.
Miles DJ, van der Sande M, Jeffries D, Kaye S, Ojuola O, Sanneh M, Cox M, Palmero MS, Touray ES, Waight P, Rowland-Jones S, Whittle H, Marchant A
PloS one 2008 Aug 6;3(8):e2905
PloS one 2008 Aug 6;3(8):e2905
EBNA1-specific T cells from patients with multiple sclerosis cross react with myelin antigens and co-produce IFN-gamma and IL-2.
Lünemann JD, Jelcić I, Roberts S, Lutterotti A, Tackenberg B, Martin R, Münz C
The Journal of experimental medicine 2008 Aug 4;205(8):1763-73
The Journal of experimental medicine 2008 Aug 4;205(8):1763-73
Beneficial effect of TRAIL on HIV burden, without detectable immune consequences.
Shepard BD, De Forni D, McNamara DR, Foli A, Rizza SA, Abraham RS, Knutson K, Wettstein PJ, Lori F, Badley AD
PloS one 2008 Aug 28;3(8):e3096
PloS one 2008 Aug 28;3(8):e3096
Safety and immunogenicity of a new tuberculosis vaccine, MVA85A, in healthy adults in South Africa.
Hawkridge T, Scriba TJ, Gelderbloem S, Smit E, Tameris M, Moyo S, Lang T, Veldsman A, Hatherill M, Merwe Lv, Fletcher HA, Mahomed H, Hill AV, Hanekom WA, Hussey GD, McShane H
The Journal of infectious diseases 2008 Aug 15;198(4):544-52
The Journal of infectious diseases 2008 Aug 15;198(4):544-52
Immunosuppressive effect of isopropanol: down-regulation of cytokine production results from the alteration of discrete transcriptional pathways in activated lymphocytes.
Désy O, Carignan D, Caruso M, de Campos-Lima PO
Journal of immunology (Baltimore, Md. : 1950) 2008 Aug 15;181(4):2348-55
Journal of immunology (Baltimore, Md. : 1950) 2008 Aug 15;181(4):2348-55
The Wilms' tumor antigen is a novel target for human CD4+ regulatory T cells: implications for immunotherapy.
Lehe C, Ghebeh H, Al-Sulaiman A, Al Qudaihi G, Al-Hussein K, Almohareb F, Chaudhri N, Alsharif F, Al-Zahrani H, Tbakhi A, Aljurf M, Dermime S
Cancer research 2008 Aug 1;68(15):6350-9
Cancer research 2008 Aug 1;68(15):6350-9
Optimal blood mononuclear cell isolation procedures for gamma interferon enzyme-linked immunospot testing of healthy Swedish and Tanzanian subjects.
Nilsson C, Aboud S, Karlén K, Hejdeman B, Urassa W, Biberfeld G
Clinical and vaccine immunology : CVI 2008 Apr;15(4):585-9
Clinical and vaccine immunology : CVI 2008 Apr;15(4):585-9
Different types of in vitro generated human monocyte-derived dendritic cells release exosomes with distinct phenotypes.
Johansson SM, Admyre C, Scheynius A, Gabrielsson S
Immunology 2008 Apr;123(4):491-9
Immunology 2008 Apr;123(4):491-9
Correlation of memory T cell responses against TRAP with protection from clinical malaria, and CD4 CD25 high T cells with susceptibility in Kenyans.
Todryk SM, Bejon P, Mwangi T, Plebanski M, Urban B, Marsh K, Hill AV, Flanagan KL
PloS one 2008 Apr 30;3(4):e2027
PloS one 2008 Apr 30;3(4):e2027
Superoxide dismutase A antigens derived from molecular analysis of sarcoidosis granulomas elicit systemic Th-1 immune responses.
Allen SS, Evans W, Carlisle J, Hajizadeh R, Nadaf M, Shepherd BE, Pride DT, Johnson JE, Drake WP
Respiratory research 2008 Apr 25;9(1):36
Respiratory research 2008 Apr 25;9(1):36
Impact of clonal competition for peptide-MHC complexes on the CD8+ T-cell repertoire selection in a persistent viral infection.
Wynn KK, Fulton Z, Cooper L, Silins SL, Gras S, Archbold JK, Tynan FE, Miles JJ, McCluskey J, Burrows SR, Rossjohn J, Khanna R
Blood 2008 Apr 15;111(8):4283-92
Blood 2008 Apr 15;111(8):4283-92
Detection of polyfunctional Mycobacterium tuberculosis-specific T cells and association with viral load in HIV-1-infected persons.
Day CL, Mkhwanazi N, Reddy S, Mncube Z, van der Stok M, Klenerman P, Walker BD
The Journal of infectious diseases 2008 Apr 1;197(7):990-9
The Journal of infectious diseases 2008 Apr 1;197(7):990-9
Broadly immunogenic HLA class I supertype-restricted elite CTL epitopes recognized in a diverse population infected with different HIV-1 subtypes.
Pérez CL, Larsen MV, Gustafsson R, Norström MM, Atlas A, Nixon DF, Nielsen M, Lund O, Karlsson AC
Journal of immunology (Baltimore, Md. : 1950) 2008 Apr 1;180(7):5092-100
Journal of immunology (Baltimore, Md. : 1950) 2008 Apr 1;180(7):5092-100
Differential functional avidity of dengue virus-specific T-cell clones for variant peptides representing heterologous and previously encountered serotypes.
Imrie A, Meeks J, Gurary A, Sukhbataar M, Kitsutani P, Effler P, Zhao Z
Journal of virology 2007 Sep;81(18):10081-91
Journal of virology 2007 Sep;81(18):10081-91
Extensive HLA class I allele promiscuity among viral CTL epitopes.
Frahm N, Yusim K, Suscovich TJ, Adams S, Sidney J, Hraber P, Hewitt HS, Linde CH, Kavanagh DG, Woodberry T, Henry LM, Faircloth K, Listgarten J, Kadie C, Jojic N, Sango K, Brown NV, Pae E, Zaman MT, Bihl F, Khatri A, John M, Mallal S, Marincola FM, Walker BD, Sette A, Heckerman D, Korber BT, Brander C
European journal of immunology 2007 Sep;37(9):2419-33
European journal of immunology 2007 Sep;37(9):2419-33
The induction and persistence of T cell IFN-gamma responses after vaccination or natural exposure is suppressed by Plasmodium falciparum.
Bejon P, Mwacharo J, Kai O, Todryk S, Keating S, Lowe B, Lang T, Mwangi TW, Gilbert SC, Peshu N, Marsh K, Hill AV
Journal of immunology (Baltimore, Md. : 1950) 2007 Sep 15;179(6):4193-201
Journal of immunology (Baltimore, Md. : 1950) 2007 Sep 15;179(6):4193-201
High T-cell response to human cytomegalovirus induces chemokine-mediated endothelial cell damage.
Bolovan-Fritts CA, Trout RN, Spector SA
Blood 2007 Sep 15;110(6):1857-63
Blood 2007 Sep 15;110(6):1857-63
Toward the development of multi-epitope p53 cancer vaccines: an in vitro assessment of CD8(+) T cell responses to HLA class I-restricted wild-type sequence p53 peptides.
Sakakura K, Chikamatsu K, Furuya N, Appella E, Whiteside TL, Deleo AB
Clinical immunology (Orlando, Fla.) 2007 Oct;125(1):43-51
Clinical immunology (Orlando, Fla.) 2007 Oct;125(1):43-51
Robust Gag-specific T cell responses characterize viremia control in HIV-2 infection.
Leligdowicz A, Yindom LM, Onyango C, Sarge-Njie R, Alabi A, Cotten M, Vincent T, da Costa C, Aaby P, Jaye A, Dong T, McMichael A, Whittle H, Rowland-Jones S
The Journal of clinical investigation 2007 Oct;117(10):3067-74
The Journal of clinical investigation 2007 Oct;117(10):3067-74
Numerical and functional defects of blood dendritic cells in early- and late-stage breast cancer.
Pinzon-Charry A, Ho CS, Maxwell T, McGuckin MA, Schmidt C, Furnival C, Pyke CM, López JA
British journal of cancer 2007 Nov 5;97(9):1251-9
British journal of cancer 2007 Nov 5;97(9):1251-9
Immunological control of chronic HIV-1 infection: HLA-mediated immune function and viral evolution in adolescents.
Bansal A, Yue L, Conway J, Yusim K, Tang J, Kappes J, Kaslow RA, Wilson CM, Goepfert PA
AIDS (London, England) 2007 Nov 30;21(18):2387-97
AIDS (London, England) 2007 Nov 30;21(18):2387-97
A viral CTL escape mutation leading to immunoglobulin-like transcript 4-mediated functional inhibition of myelomonocytic cells.
Lichterfeld M, Kavanagh DG, Williams KL, Moza B, Mui SK, Miura T, Sivamurthy R, Allgaier R, Pereyra F, Trocha A, Feeney M, Gandhi RT, Rosenberg ES, Altfeld M, Allen TM, Allen R, Walker BD, Sundberg EJ, Yu XG
The Journal of experimental medicine 2007 Nov 26;204(12):2813-24
The Journal of experimental medicine 2007 Nov 26;204(12):2813-24
Enhanced detection of human immunodeficiency virus type 1 (HIV-1) Nef-specific T cells recognizing multiple variants in early HIV-1 infection.
Malhotra U, Li F, Nolin J, Allison M, Zhao H, Mullins JI, Self S, McElrath MJ
Journal of virology 2007 May;81(10):5225-37
Journal of virology 2007 May;81(10):5225-37
Hepatitis B virus splice-generated protein induces T-cell responses in HLA-transgenic mice and hepatitis B virus-infected patients.
Mancini-Bourgine M, Bayard F, Soussan P, Deng Q, Lone YC, Kremsdorf D, Michel ML
Journal of virology 2007 May;81(10):4963-72
Journal of virology 2007 May;81(10):4963-72
Phase I dose escalation safety and immunogenicity trial of Plasmodium falciparum apical membrane protein (AMA-1) FMP2.1, adjuvanted with AS02A, in malaria-naïve adults at the Walter Reed Army Institute of Research.
Polhemus ME, Magill AJ, Cummings JF, Kester KE, Ockenhouse CF, Lanar DE, Dutta S, Barbosa A, Soisson L, Diggs CL, Robinson SA, Haynes JD, Stewart VA, Ware LA, Brando C, Krzych U, Bowden RA, Cohen JD, Dubois MC, Ofori-Anyinam O, De-Kock E, Ballou WR, Heppner DG Jr
Vaccine 2007 May 22;25(21):4203-12
Vaccine 2007 May 22;25(21):4203-12
The length of lipids bound to human CD1d molecules modulates the affinity of NKT cell TCR and the threshold of NKT cell activation.
McCarthy C, Shepherd D, Fleire S, Stronge VS, Koch M, Illarionov PA, Bossi G, Salio M, Denkberg G, Reddington F, Tarlton A, Reddy BG, Schmidt RR, Reiter Y, Griffiths GM, van der Merwe PA, Besra GS, Jones EY, Batista FD, Cerundolo V
The Journal of experimental medicine 2007 May 14;204(5):1131-44
The Journal of experimental medicine 2007 May 14;204(5):1131-44
Cytokine responses in acute and persistent human parvovirus B19 infection.
Isa A, Lundqvist A, Lindblom A, Tolfvenstam T, Broliden K
Clinical and experimental immunology 2007 Mar;147(3):419-25
Clinical and experimental immunology 2007 Mar;147(3):419-25
CD8 tumor-infiltrating lymphocytes are predictive of survival in muscle-invasive urothelial carcinoma.
Sharma P, Shen Y, Wen S, Yamada S, Jungbluth AA, Gnjatic S, Bajorin DF, Reuter VE, Herr H, Old LJ, Sato E
Proceedings of the National Academy of Sciences of the United States of America 2007 Mar 6;104(10):3967-72
Proceedings of the National Academy of Sciences of the United States of America 2007 Mar 6;104(10):3967-72
A dual color ELISPOT method for the simultaneous detection of IL-2 and IFN-gamma HIV-specific immune responses.
Boulet S, Ndongala ML, Peretz Y, Boisvert MP, Boulassel MR, Tremblay C, Routy JP, Sekaly RP, Bernard NF
Journal of immunological methods 2007 Mar 30;320(1-2):18-29
Journal of immunological methods 2007 Mar 30;320(1-2):18-29
Fully differentiated HIV-1 specific CD8+ T effector cells are more frequently detectable in controlled than in progressive HIV-1 infection.
Addo MM, Draenert R, Rathod A, Verrill CL, Davis BT, Gandhi RT, Robbins GK, Basgoz NO, Stone DR, Cohen DE, Johnston MN, Flynn T, Wurcel AG, Rosenberg ES, Altfeld M, Walker BD
PloS one 2007 Mar 28;2(3):e321
PloS one 2007 Mar 28;2(3):e321
HIV patients developing primary CNS lymphoma lack EBV-specific CD4+ T cell function irrespective of absolute CD4+ T cell counts.
Gasser O, Bihl FK, Wolbers M, Loggi E, Steffen I, Hirsch HH, Günthard HF, Walker BD, Brander C, Battegay M, Hess C, Swiss HIV Cohort Study
PLoS medicine 2007 Mar 27;4(3):e96
PLoS medicine 2007 Mar 27;4(3):e96
Bacterial superantigen facilitates epithelial presentation of allergen to T helper 2 cells.
Ardern-Jones MR, Black AP, Bateman EA, Ogg GS
Proceedings of the National Academy of Sciences of the United States of America 2007 Mar 27;104(13):5557-62
Proceedings of the National Academy of Sciences of the United States of America 2007 Mar 27;104(13):5557-62
Facilitating matched pairing and expression of TCR chains introduced into human T cells.
Kuball J, Dossett ML, Wolfl M, Ho WY, Voss RH, Fowler C, Greenberg PD
Blood 2007 Mar 15;109(6):2331-8
Blood 2007 Mar 15;109(6):2331-8
Cytomegalovirus infection in Gambian infants leads to profound CD8 T-cell differentiation.
Miles DJ, van der Sande M, Jeffries D, Kaye S, Ismaili J, Ojuola O, Sanneh M, Touray ES, Waight P, Rowland-Jones S, Whittle H, Marchant A
Journal of virology 2007 Jun;81(11):5766-76
Journal of virology 2007 Jun;81(11):5766-76
T-cell recognition of the HspX protein of Mycobacterium tuberculosis correlates with latent M. tuberculosis infection but not with M. bovis BCG vaccination.
Geluk A, Lin MY, van Meijgaarden KE, Leyten EM, Franken KL, Ottenhoff TH, Klein MR
Infection and immunity 2007 Jun;75(6):2914-21
Infection and immunity 2007 Jun;75(6):2914-21
Human infant respiratory syncytial virus (RSV)-specific type 1 and 2 cytokine responses ex vivo during primary RSV infection.
Lee FE, Walsh EE, Falsey AR, Lumb ME, Okam NV, Liu N, Divekar AA, Hall CB, Mosmann TR
The Journal of infectious diseases 2007 Jun 15;195(12):1779-88
The Journal of infectious diseases 2007 Jun 15;195(12):1779-88
Availability of a diversely avid CD8+ T cell repertoire specific for the subdominant HLA-A2-restricted HIV-1 Gag p2419-27 epitope.
Schaubert KL, Price DA, Frahm N, Li J, Ng HL, Joseph A, Paul E, Majumder B, Ayyavoo V, Gostick E, Adams S, Marincola FM, Sewell AK, Altfeld M, Brenchley JM, Douek DC, Yang OO, Brander C, Goldstein H, Kan-Mitchell J
Journal of immunology (Baltimore, Md. : 1950) 2007 Jun 15;178(12):7756-66
Journal of immunology (Baltimore, Md. : 1950) 2007 Jun 15;178(12):7756-66
Recognition of a defined region within p24 gag by CD8+ T cells during primary human immunodeficiency virus type 1 infection in individuals expressing protective HLA class I alleles.
Streeck H, Lichterfeld M, Alter G, Meier A, Teigen N, Yassine-Diab B, Sidhu HK, Little S, Kelleher A, Routy JP, Rosenberg ES, Sekaly RP, Walker BD, Altfeld M
Journal of virology 2007 Jul;81(14):7725-31
Journal of virology 2007 Jul;81(14):7725-31
Direct comparison of antigen production and induction of apoptosis by canarypox virus- and modified vaccinia virus ankara-human immunodeficiency virus vaccine vectors.
Zhang X, Cassis-Ghavami F, Eller M, Currier J, Slike BM, Chen X, Tartaglia J, Marovich M, Spearman P
Journal of virology 2007 Jul;81(13):7022-33
Journal of virology 2007 Jul;81(13):7022-33
Mycobacterium tuberculosis Antigen 85A induces Th-1 immune responses in systemic sarcoidosis.
Hajizadeh R, Sato H, Carlisle J, Nadaf MT, Evans W, Shepherd BE, Miller RF, Kalams SA, Drake WP
Journal of clinical immunology 2007 Jul;27(4):445-54
Journal of clinical immunology 2007 Jul;27(4):445-54
Tracking virus-specific CD4+ T cells during and after acute hepatitis C virus infection.
Lucas M, Ulsenheimer A, Pfafferot K, Heeg MH, Gaudieri S, Grüner N, Rauch A, Gerlach JT, Jung MC, Zachoval R, Pape GR, Schraut W, Santantonio T, Nitschko H, Obermeier M, Phillips R, Scriba TJ, Semmo N, Day C, Weber JN, Fidler S, Thimme R, Haberstroh A, Baumert TF, Klenerman P, Diepolder HM
PloS one 2007 Jul 25;2(7):e649
PloS one 2007 Jul 25;2(7):e649
Antigen-loading compartments for major histocompatibility complex class II molecules continuously receive input from autophagosomes.
Schmid D, Pypaert M, Münz C
Immunity 2007 Jan;26(1):79-92
Immunity 2007 Jan;26(1):79-92
Decreased up-regulation of the interleukin-12Rbeta2-chain and interferon-gamma secretion and increased number of forkhead box P3-expressing cells in patients with a history of chronic Lyme borreliosis compared with asymptomatic Borrelia-exposed individuals.
Jarefors S, Janefjord CK, Forsberg P, Jenmalm MC, Ekerfelt C
Clinical and experimental immunology 2007 Jan;147(1):18-27
Clinical and experimental immunology 2007 Jan;147(1):18-27
Substantial improvements in performance indicators achieved in a peripheral blood mononuclear cell cryopreservation quality assurance program using single donor samples.
Dyer WB, Pett SL, Sullivan JS, Emery S, Cooper DA, Kelleher AD, Lloyd A, Lewin SR
Clinical and vaccine immunology : CVI 2007 Jan;14(1):52-9
Clinical and vaccine immunology : CVI 2007 Jan;14(1):52-9
Mutually exclusive T-cell receptor induction and differential susceptibility to human immunodeficiency virus type 1 mutational escape associated with a two-amino-acid difference between HLA class I subtypes.
Yu XG, Lichterfeld M, Chetty S, Williams KL, Mui SK, Miura T, Frahm N, Feeney ME, Tang Y, Pereyra F, Labute MX, Pfafferott K, Leslie A, Crawford H, Allgaier R, Hildebrand W, Kaslow R, Brander C, Allen TM, Rosenberg ES, Kiepiela P, Vajpayee M, Goepfert PA, Altfeld M, Goulder PJ, Walker BD
Journal of virology 2007 Feb;81(4):1619-31
Journal of virology 2007 Feb;81(4):1619-31
HLA class I binding promiscuity of the CD8 T-cell epitopes of human papillomavirus type 16 E6 protein.
Nakagawa M, Kim KH, Gillam TM, Moscicki AB
Journal of virology 2007 Feb;81(3):1412-23
Journal of virology 2007 Feb;81(3):1412-23
Proteasome-independent major histocompatibility complex class I cross-presentation mediated by papaya mosaic virus-like particles leads to expansion of specific human T cells.
Leclerc D, Beauseigle D, Denis J, Morin H, Paré C, Lamarre A, Lapointe R
Journal of virology 2007 Feb;81(3):1319-26
Journal of virology 2007 Feb;81(3):1319-26
Genomic analysis of HIV type 1 strains derived from a mother and child pair of long-term nonprogressors.
Reinis M, Weiser B, Kuiken C, Dong T, Lang D, Nachman S, Zhang Y, Rowland-Jones S, Burger H
AIDS research and human retroviruses 2007 Feb;23(2):309-15
AIDS research and human retroviruses 2007 Feb;23(2):309-15
Combined therapy of transcatheter hepatic arterial embolization with intratumoral dendritic cell infusion for hepatocellular carcinoma: clinical safety.
Nakamoto Y, Mizukoshi E, Tsuji H, Sakai Y, Kitahara M, Arai K, Yamashita T, Yokoyama K, Mukaida N, Matsushima K, Matsui O, Kaneko S
Clinical and experimental immunology 2007 Feb;147(2):296-305
Clinical and experimental immunology 2007 Feb;147(2):296-305
MUC1-specific immune therapy generates a strong anti-tumor response in a MUC1-tolerant colon cancer model.
Mukherjee P, Pathangey LB, Bradley JB, Tinder TL, Basu GD, Akporiaye ET, Gendler SJ
Vaccine 2007 Feb 19;25(9):1607-18
Vaccine 2007 Feb 19;25(9):1607-18
Phase 2 study of an HIV-1 canarypox vaccine (vCP1452) alone and in combination with rgp120: negative results fail to trigger a phase 3 correlates trial.
Russell ND, Graham BS, Keefer MC, McElrath MJ, Self SG, Weinhold KJ, Montefiori DC, Ferrari G, Horton H, Tomaras GD, Gurunathan S, Baglyos L, Frey SE, Mulligan MJ, Harro CD, Buchbinder SP, Baden LR, Blattner WA, Koblin BA, Corey L, National Institute of Allergy and Infectious Diseases HIV Vaccine Trials Network
Journal of acquired immune deficiency syndromes (1999) 2007 Feb 1;44(2):203-12
Journal of acquired immune deficiency syndromes (1999) 2007 Feb 1;44(2):203-12
Distinct memory CD4+ T-cell subsets mediate immune recognition of Epstein Barr virus nuclear antigen 1 in healthy virus carriers.
Heller KN, Upshaw J, Seyoum B, Zebroski H, Münz C
Blood 2007 Feb 1;109(3):1138-46
Blood 2007 Feb 1;109(3):1138-46
Human immunodeficiency virus-specific CD8+ T-cell activity is detectable from birth in the majority of in utero-infected infants.
Thobakgale CF, Ramduth D, Reddy S, Mkhwanazi N, de Pierres C, Moodley E, Mphatswe W, Blanckenberg N, Cengimbo A, Prendergast A, Tudor-Williams G, Dong K, Jeena P, Kindra G, Bobat R, Coovadia H, Kiepiela P, Walker BD, Goulder PJ
Journal of virology 2007 Dec;81(23):12775-84
Journal of virology 2007 Dec;81(23):12775-84
Multiple Mycobacterium antigens induce interferon-gamma production from sarcoidosis peripheral blood mononuclear cells.
Carlisle J, Evans W, Hajizadeh R, Nadaf M, Shepherd B, Ott RD, Richter K, Drake W
Clinical and experimental immunology 2007 Dec;150(3):460-8
Clinical and experimental immunology 2007 Dec;150(3):460-8
Rapid diagnosis of smear-negative tuberculosis using immunology and microbiology with induced sputum in HIV-infected and uninfected individuals.
Breen RA, Hardy GA, Perrin FM, Lear S, Kinloch S, Smith CJ, Cropley I, Janossy G, Lipman MC
PloS one 2007 Dec 19;2(12):e1335
PloS one 2007 Dec 19;2(12):e1335
A phase I pilot study of autologous heat shock protein vaccine HSPPC-96 in patients with resected pancreatic adenocarcinoma.
Maki RG, Livingston PO, Lewis JJ, Janetzki S, Klimstra D, Desantis D, Srivastava PK, Brennan MF
Digestive diseases and sciences 2007 Aug;52(8):1964-72
Digestive diseases and sciences 2007 Aug;52(8):1964-72
Cross-reactive T-cell responses to the nonstructural regions of dengue viruses among dengue fever and dengue hemorrhagic fever patients in Malaysia.
Appanna R, Huat TL, See LL, Tan PL, Vadivelu J, Devi S
Clinical and vaccine immunology : CVI 2007 Aug;14(8):969-77
Clinical and vaccine immunology : CVI 2007 Aug;14(8):969-77
Human polyomavirus type 1 (BK virus) agnoprotein is abundantly expressed but immunologically ignored.
Leuenberger D, Andresen PA, Gosert R, Binggeli S, Ström EH, Bodaghi S, Rinaldo CH, Hirsch HH
Clinical and vaccine immunology : CVI 2007 Aug;14(8):959-68
Clinical and vaccine immunology : CVI 2007 Aug;14(8):959-68
Human immunodeficiency virus type 1 specific cytotoxic T lymphocyte responses in Chinese infected with HIV-1 B'/C Recombinant (CRF07_BC).
Chen J, Hong K, Jia M, Liu H, Zhang Y, Liu S, Zhang X, Zhao H, Peng H, Ma P, Xing H, Ruan Y, Williams KL, Yu XG, Altfeld M, Walker BD, Shao Y
Retrovirology 2007 Aug 30;4:62
Retrovirology 2007 Aug 30;4:62
Utility of interferon-gamma ELISPOT assay responses in highly tuberculosis-exposed patients with advanced HIV infection in South Africa.
Lawn SD, Bangani N, Vogt M, Bekker LG, Badri M, Ntobongwana M, Dockrell HM, Wilkinson RJ, Wood R
BMC infectious diseases 2007 Aug 28;7:99
BMC infectious diseases 2007 Aug 28;7:99
Human CD8+ T cell memory generation in Puumala hantavirus infection occurs after the acute phase and is associated with boosting of EBV-specific CD8+ memory T cells.
Tuuminen T, Kekäläinen E, Mäkelä S, Ala-Houhala I, Ennis FA, Hedman K, Mustonen J, Vaheri A, Arstila TP
Journal of immunology (Baltimore, Md. : 1950) 2007 Aug 1;179(3):1988-95
Journal of immunology (Baltimore, Md. : 1950) 2007 Aug 1;179(3):1988-95
Characterization of hepatitis B virus (HBV)-specific T-cell dysfunction in chronic HBV infection.
Boni C, Fisicaro P, Valdatta C, Amadei B, Di Vincenzo P, Giuberti T, Laccabue D, Zerbini A, Cavalli A, Missale G, Bertoletti A, Ferrari C
Journal of virology 2007 Apr;81(8):4215-25
Journal of virology 2007 Apr;81(8):4215-25
Evaluation of alloreactivity in responder-stimulator pairs by determination of gamma interferon-producing cells and cytotoxic-T-lymphocyte precursor frequencies.
Sizzano F, Dametto E, Amoroso A
Clinical and vaccine immunology : CVI 2007 Apr;14(4):481-3
Clinical and vaccine immunology : CVI 2007 Apr;14(4):481-3
Detection of human papillomavirus type 16-specific T lymphocytes by a recombinant vaccinia virus-based enzyme-linked immunospot assay.
Kim KH, Greenfield W, Shotts E, Nakagawa M
Clinical and vaccine immunology : CVI 2007 Apr;14(4):362-8
Clinical and vaccine immunology : CVI 2007 Apr;14(4):362-8
Diagnosis of tuberculosis by an enzyme-linked immunospot assay for interferon-gamma.
Wang JY, Chou CH, Lee LN, Hsu HL, Jan IS, Hsueh PR, Yang PC, Luh KT
Emerging infectious diseases 2007 Apr;13(4):553-8
Emerging infectious diseases 2007 Apr;13(4):553-8
CD4+ CD25+ regulatory T cells in human pregnancy: development of a Treg-MLC-ELISPOT suppression assay and indications of paternal specific Tregs.
Mjösberg J, Berg G, Ernerudh J, Ekerfelt C
Immunology 2007 Apr;120(4):456-66
Immunology 2007 Apr;120(4):456-66
CD4+ T cell targeting of human immunodeficiency virus type 1 (HIV-1) peptide sequences present in vivo during chronic, progressive HIV-1 disease.
Boritz E, Rapaport EL, Campbell TB, Koeppe JR, Wilson CC
Virology 2007 Apr 25;361(1):34-44
Virology 2007 Apr 25;361(1):34-44
Immunization with HIV protease peptides linked to syngeneic erythrocytes.
Boberg A, Dominici S, Brave A, Hallermalm K, Hinkula J, Magnani M, Wahren B
Infectious agents and cancer 2007 Apr 18;2:9
Infectious agents and cancer 2007 Apr 18;2:9
Splenic accumulation of IL-10 mRNA in T cells distinct from CD4+CD25+ (Foxp3) regulatory T cells in human visceral leishmaniasis.
Nylén S, Maurya R, Eidsmo L, Manandhar KD, Sundar S, Sacks D
The Journal of experimental medicine 2007 Apr 16;204(4):805-17
The Journal of experimental medicine 2007 Apr 16;204(4):805-17
HLA-DQB1*02-restricted HPV-16 E7 peptide-specific CD4+ T-cell immune responses correlate with regression of HPV-16-associated high-grade squamous intraepithelial lesions.
Peng S, Trimble C, Wu L, Pardoll D, Roden R, Hung CF, Wu TC
Clinical cancer research : an official journal of the American Association for Cancer Research 2007 Apr 15;13(8):2479-87
Clinical cancer research : an official journal of the American Association for Cancer Research 2007 Apr 15;13(8):2479-87
Generation of clinical grade dendritic cells with capacity to produce biologically active IL-12p70.
Zobywalski A, Javorovic M, Frankenberger B, Pohla H, Kremmer E, Bigalke I, Schendel DJ
Journal of translational medicine 2007 Apr 12;5:18
Journal of translational medicine 2007 Apr 12;5:18
A phase I, randomized study of combined IL-2 and therapeutic immunisation with antiretroviral therapy.
Hardy GA, Imami N, Nelson MR, Sullivan AK, Moss R, Aasa-Chapman MM, Gazzard B, Gotch FM
Journal of immune based therapies and vaccines 2007 Apr 11;5:6
Journal of immune based therapies and vaccines 2007 Apr 11;5:6
Pilot phase III immunotherapy study in early-stage breast cancer patients using oxidized mannan-MUC1 [ISRCTN71711835].
Apostolopoulos V, Pietersz GA, Tsibanis A, Tsikkinis A, Drakaki H, Loveland BE, Piddlesden SJ, Plebanski M, Pouniotis DS, Alexis MN, McKenzie IF, Vassilaros S
Breast cancer research : BCR 2006;8(3):R27
Breast cancer research : BCR 2006;8(3):R27
Down-regulation of interferon-gamma parallels clinical response to selective leukocyte apheresis in patients with inflammatory bowel disease: a 12-month follow-up study.
Muratov V, Lundahl J, Ulfgren AK, Elvin K, Fehrman I, Ahlborg N, Ost A, Hittel N, Saniabadi A, Löfberg R
International journal of colorectal disease 2006 Sep;21(6):493-504
International journal of colorectal disease 2006 Sep;21(6):493-504
A reproducible method for the enumeration of functional (cytokine producing) versus non-functional peptide-specific cytotoxic T lymphocytes in human peripheral blood.
Markovic SN, Nevala WK, Uhl CB, Celis E, McKean DJ
Clinical and experimental immunology 2006 Sep;145(3):438-47
Clinical and experimental immunology 2006 Sep;145(3):438-47
A T2 cytokine environment may not limit T1 responses in human immunodeficiency virus patients with a favourable response to antiretroviral therapy.
Price P, Keane NM, Lee S, Lim AF, McKinnon EJ, French MA
Immunology 2006 Sep;119(1):74-82
Immunology 2006 Sep;119(1):74-82
HLA-A24 and survivin: possibilities in therapeutic vaccination against cancer.
Andersen MH, Soerensen RB, Becker JC, thor Straten P
Journal of translational medicine 2006 Sep 4;4:38
Journal of translational medicine 2006 Sep 4;4:38
Adoptive immunotherapy with allodepleted donor T-cells improves immune reconstitution after haploidentical stem cell transplantation.
Amrolia PJ, Muccioli-Casadei G, Huls H, Adams S, Durett A, Gee A, Yvon E, Weiss H, Cobbold M, Gaspar HB, Rooney C, Kuehnle I, Ghetie V, Schindler J, Krance R, Heslop HE, Veys P, Vitetta E, Brenner MK
Blood 2006 Sep 15;108(6):1797-808
Blood 2006 Sep 15;108(6):1797-808
Human T-cell responses to vaccinia virus envelope proteins.
Tang J, Murtadha M, Schnell M, Eisenlohr LC, Hooper J, Flomenberg P
Journal of virology 2006 Oct;80(20):10010-20
Journal of virology 2006 Oct;80(20):10010-20
Persistent high frequencies of varicella-zoster virus ORF4 protein-specific CD4+ T cells after primary infection.
Jones L, Black AP, Malavige GN, Ogg GS
Journal of virology 2006 Oct;80(19):9772-8
Journal of virology 2006 Oct;80(19):9772-8
Tumor mRNA-transfected dendritic cells stimulate the generation of CTL that recognize neuroblastoma-associated antigens and kill tumor cells: immunotherapeutic implications.
Morandi F, Chiesa S, Bocca P, Millo E, Salis A, Solari M, Pistoia V, Prigione I
Neoplasia (New York, N.Y.) 2006 Oct;8(10):833-42
Neoplasia (New York, N.Y.) 2006 Oct;8(10):833-42
A phase 2b randomised trial of the candidate malaria vaccines FP9 ME-TRAP and MVA ME-TRAP among children in Kenya.
Bejon P, Mwacharo J, Kai O, Mwangi T, Milligan P, Todryk S, Keating S, Lang T, Lowe B, Gikonyo C, Molyneux C, Fegan G, Gilbert SC, Peshu N, Marsh K, Hill AV
PLoS clinical trials 2006 Oct 20;1(6):e29
PLoS clinical trials 2006 Oct 20;1(6):e29
Early gamma interferon and interleukin-2 responses to vaccination predict the late resting memory in malaria-naïve and malaria-exposed individuals.
Bejon P, Keating S, Mwacharo J, Kai OK, Dunachie S, Walther M, Berthoud T, Lang T, Epstein J, Carucci D, Moris P, Cohen J, Gilbert SC, Peshu N, Marsh K, Hill AV
Infection and immunity 2006 Nov;74(11):6331-8
Infection and immunity 2006 Nov;74(11):6331-8
The highly attenuated vaccinia virus strain modified virus Ankara induces apoptosis in melanoma cells and allows bystander dendritic cells to generate a potent anti-tumoral immunity.
Greiner S, Humrich JY, Thuman P, Sauter B, Schuler G, Jenne L
Clinical and experimental immunology 2006 Nov;146(2):344-53
Clinical and experimental immunology 2006 Nov;146(2):344-53
The polycomb group proteins, BMI-1 and EZH2, are tumour-associated antigens.
Steele JC, Torr EE, Noakes KL, Kalk E, Moss PA, Reynolds GM, Hubscher SG, van Lohuizen M, Adams DH, Young LS
British journal of cancer 2006 Nov 6;95(9):1202-11
British journal of cancer 2006 Nov 6;95(9):1202-11
Treatment of solid organ transplant recipients with autologous Epstein Barr virus-specific cytotoxic T lymphocytes (CTLs).
Savoldo B, Goss JA, Hammer MM, Zhang L, Lopez T, Gee AP, Lin YF, Quiros-Tejeira RE, Reinke P, Schubert S, Gottschalk S, Finegold MJ, Brenner MK, Rooney CM, Heslop HE
Blood 2006 Nov 1;108(9):2942-9
Blood 2006 Nov 1;108(9):2942-9
Induction of multifunctional human immunodeficiency virus type 1 (HIV-1)-specific T cells capable of proliferation in healthy subjects by using a prime-boost regimen of DNA- and modified vaccinia virus Ankara-vectored vaccines expressing HIV-1 Gag coupled to CD8+ T-cell epitopes.
Goonetilleke N, Moore S, Dally L, Winstone N, Cebere I, Mahmoud A, Pinheiro S, Gillespie G, Brown D, Loach V, Roberts J, Guimaraes-Walker A, Hayes P, Loughran K, Smith C, De Bont J, Verlinde C, Vooijs D, Schmidt C, Boaz M, Gilmour J, Fast P, Dorrell L, Hanke T, McMichael AJ
Journal of virology 2006 May;80(10):4717-28
Journal of virology 2006 May;80(10):4717-28
The 6-kilodalton early secreted antigenic target-responsive, asymptomatic contacts of tuberculosis patients express elevated levels of interleukin-4 and reduced levels of gamma interferon.
Demissie A, Wassie L, Abebe M, Aseffa A, Rook G, Zumla A, Andersen P, Doherty TM, VACSEL Study Group
Infection and immunity 2006 May;74(5):2817-22
Infection and immunity 2006 May;74(5):2817-22
Identification of a major histocompatibility complex class I-restricted T-cell epitope in the tumour-associated antigen, 5T4.
Redchenko I, Harrop R, Ryan MG, Hawkins RE, Carroll MW
Immunology 2006 May;118(1):50-7
Immunology 2006 May;118(1):50-7
Elicitation from virus-naive individuals of cytotoxic T lymphocytes directed against conserved HIV-1 epitopes.
Reche PA, Keskin DB, Hussey RE, Ancuta P, Gabuzda D, Reinherz EL
Medical immunology (London, England) 2006 May 18;5:1
Medical immunology (London, England) 2006 May 18;5:1
Maintenance of viral suppression in HIV-1-infected HLA-B*57+ elite suppressors despite CTL escape mutations.
Bailey JR, Williams TM, Siliciano RF, Blankson JN
The Journal of experimental medicine 2006 May 15;203(5):1357-69
The Journal of experimental medicine 2006 May 15;203(5):1357-69
Natural killer cell function is well preserved in asymptomatic human immunodeficiency virus type 2 (HIV-2) infection but similar to that of HIV-1 infection when CD4 T-cell counts fall.
Nuvor SV, van der Sande M, Rowland-Jones S, Whittle H, Jaye A
Journal of virology 2006 Mar;80(5):2529-38
Journal of virology 2006 Mar;80(5):2529-38
Antagonism of HIV-specific CD4+ T cells by C-terminal truncation of a minimum epitope.
Norris PJ, Stone JD, Anikeeva N, Heitman JW, Wilson IC, Hirschkorn DF, Clark MJ, Moffett HF, Cameron TO, Sykulev Y, Stern LJ, Walker BD
Molecular immunology 2006 Mar;43(9):1349-57
Molecular immunology 2006 Mar;43(9):1349-57
Fluctuations of functionally distinct CD8+ T-cell clonotypes demonstrate flexibility of the HIV-specific TCR repertoire.
Meyer-Olson D, Brady KW, Bartman MT, O'Sullivan KM, Simons BC, Conrad JA, Duncan CB, Lorey S, Siddique A, Draenert R, Addo M, Altfeld M, Rosenberg E, Allen TM, Walker BD, Kalams SA
Blood 2006 Mar 15;107(6):2373-83
Blood 2006 Mar 15;107(6):2373-83
The hypervariable immunodominant NP418-426 epitope from the influenza A virus nucleoprotein is recognized by cytotoxic T lymphocytes with high functional avidity.
Boon AC, de Mutsert G, Fouchier RA, Osterhaus AD, Rimmelzwaan GF
Journal of virology 2006 Jun;80(12):6024-32
Journal of virology 2006 Jun;80(12):6024-32
Diversity of the CD8+ T-cell response to herpes simplex virus type 2 proteins among persons with genital herpes.
Hosken N, McGowan P, Meier A, Koelle DM, Sleath P, Wagener F, Elliott M, Grabstein K, Posavad C, Corey L
Journal of virology 2006 Jun;80(11):5509-15
Journal of virology 2006 Jun;80(11):5509-15
Relationship between maternal and child cytokine responses to allergen and phytohaemagglutinin 2 years after delivery.
Larsson AK, Nilsson C, Höglind A, Sverremark-Ekström E, Lilja G, Troye-Blomberg M
Clinical and experimental immunology 2006 Jun;144(3):401-8
Clinical and experimental immunology 2006 Jun;144(3):401-8
Evaluation of the interlaboratory concordance in quantification of human immunodeficiency virus-specific T cells with a gamma interferon enzyme-linked immunospot assay.
Samri A, Durier C, Urrutia A, Sanchez I, Gahery-Segard H, Imbart S, Sinet M, Tartour E, Aboulker JP, Autran B, Venet A, ANRS ELISpot Standardization Group
Clinical and vaccine immunology : CVI 2006 Jun;13(6):684-97
Clinical and vaccine immunology : CVI 2006 Jun;13(6):684-97
Lyme borreliosis reinfection: might it be explained by a gender difference in immune response?
Jarefors S, Bennet L, You E, Forsberg P, Ekerfelt C, Berglund J, Ernerudh J
Immunology 2006 Jun;118(2):224-32
Immunology 2006 Jun;118(2):224-32
Rectal nitric oxide as biomarker in the treatment of inflammatory bowel disease: responders versus nonresponders.
Ljung T, Lundberg S, Varsanyi M, Johansson C, Schmidt PT, Herulf M, Lundberg JO, Hellstrom PM
World journal of gastroenterology 2006 Jun 7;12(21):3386-92
World journal of gastroenterology 2006 Jun 7;12(21):3386-92
Passive sexual transmission of human immunodeficiency virus type 1 variants and adaptation in new hosts.
Frater AJ, Edwards CT, McCarthy N, Fox J, Brown H, Milicic A, Mackie N, Pillay T, Drijfhout JW, Dustan S, Clarke JR, Holmes EC, Zhang HT, Pfafferott K, Goulder PJ, McClure MO, Weber J, Phillips RE, Fidler S
Journal of virology 2006 Jul;80(14):7226-34
Journal of virology 2006 Jul;80(14):7226-34
In vivo antigen delivery by a Salmonella typhimurium type III secretion system for therapeutic cancer vaccines.
Nishikawa H, Sato E, Briones G, Chen LM, Matsuo M, Nagata Y, Ritter G, Jäger E, Nomura H, Kondo S, Tawara I, Kato T, Shiku H, Old LJ, Galán JE, Gnjatic S
The Journal of clinical investigation 2006 Jul;116(7):1946-54
The Journal of clinical investigation 2006 Jul;116(7):1946-54
Characterization of the IFN-gamma T-cell responses to immediate early antigens in humans with genital herpes.
Braun RP, Payne LG, Dong L
Virology journal 2006 Jul 5;3:54
Virology journal 2006 Jul 5;3:54
Rapid qualitative and quantitative analysis of T-cell responses in HIV-1-infected individuals receiving successful HAART and HIV-1 sero-negative controls: concomitant assessment of perforin, IFN-gamma and IL-4 secretion.
Burton CT, Gotch F, Imami N
Journal of immunological methods 2006 Jan 20;308(1-2):216-30
Journal of immunological methods 2006 Jan 20;308(1-2):216-30
Control of human immunodeficiency virus replication by cytotoxic T lymphocytes targeting subdominant epitopes.
Frahm N, Kiepiela P, Adams S, Linde CH, Hewitt HS, Sango K, Feeney ME, Addo MM, Lichterfeld M, Lahaie MP, Pae E, Wurcel AG, Roach T, St John MA, Altfeld M, Marincola FM, Moore C, Mallal S, Carrington M, Heckerman D, Allen TM, Mullins JI, Korber BT, Goulder PJ, Walker BD, Brander C
Nature immunology 2006 Feb;7(2):173-8
Nature immunology 2006 Feb;7(2):173-8
Reduced number of interleukin-12 secreting cells in patients with Lyme borreliosis previously exposed to Anaplasma phagocytophilum.
Jarefors S, Karlsson M, Forsberg P, Eliasson I, Ernerudh J, Ekerfelt C
Clinical and experimental immunology 2006 Feb;143(2):322-8
Clinical and experimental immunology 2006 Feb;143(2):322-8
Recognition of stage-specific mycobacterial antigens differentiates between acute and latent infections with Mycobacterium tuberculosis.
Demissie A, Leyten EM, Abebe M, Wassie L, Aseffa A, Abate G, Fletcher H, Owiafe P, Hill PC, Brookes R, Rook G, Zumla A, Arend SM, Klein M, Ottenhoff TH, Andersen P, Doherty TM, VACSEL Study Group
Clinical and vaccine immunology : CVI 2006 Feb;13(2):179-86
Clinical and vaccine immunology : CVI 2006 Feb;13(2):179-86
Engagement of CD83 ligand induces prolonged expansion of CD8+ T cells and preferential enrichment for antigen specificity.
Hirano N, Butler MO, Xia Z, Ansén S, von Bergwelt-Baildon MS, Neuberg D, Freeman GJ, Nadler LM
Blood 2006 Feb 15;107(4):1528-36
Blood 2006 Feb 15;107(4):1528-36
Protein vaccines induce uncommitted IL-2-secreting human and mouse CD4 T cells, whereas infections induce more IFN-gamma-secreting cells.
Divekar AA, Zaiss DM, Lee FE, Liu D, Topham DJ, Sijts AJ, Mosmann TR
Journal of immunology (Baltimore, Md. : 1950) 2006 Feb 1;176(3):1465-73
Journal of immunology (Baltimore, Md. : 1950) 2006 Feb 1;176(3):1465-73
Tumor infiltrating T lymphocytes in colorectal cancer: Tumor-selective activation and cytotoxic activity in situ.
Koch M, Beckhove P, Op den Winkel J, Autenrieth D, Wagner P, Nummer D, Specht S, Antolovic D, Galindo L, Schmitz-Winnenthal FH, Schirrmacher V, Büchler MW, Weitz J
Annals of surgery 2006 Dec;244(6):986-92; discussion 992-3
Annals of surgery 2006 Dec;244(6):986-92; discussion 992-3
Combinations of common chronic paediatric diseases deviate the immune response in diverging directions.
Nilsson L, Kivling A, Jalmelid M, Fälth Magnusson K, Faresjö M
Clinical and experimental immunology 2006 Dec;146(3):433-42
Clinical and experimental immunology 2006 Dec;146(3):433-42
Nickel, cobalt, chromium, palladium and gold induce a mixed Th1- and Th2-type cytokine response in vitro in subjects with contact allergy to the respective metals.
Minang JT, Areström I, Troye-Blomberg M, Lundeberg L, Ahlborg N
Clinical and experimental immunology 2006 Dec;146(3):417-26
Clinical and experimental immunology 2006 Dec;146(3):417-26
Large scale analysis of pediatric antiviral CD8+ T cell populations reveals sustained, functional and mature responses.
Komatsu H, Inui A, Sogo T, Fujisawa T, Nagasaka H, Nonoyama S, Sierro S, Northfield J, Lucas M, Vargas A, Klenerman P
Immunity & ageing : I & A 2006 Dec 8;3:11
Immunity & ageing : I & A 2006 Dec 8;3:11
CD4+CD25+FOXP3+ regulatory T cells suppress anti-tumor immune responses in patients with colorectal cancer.
Clarke SL, Betts GJ, Plant A, Wright KL, El-Shanawany TM, Harrop R, Torkington J, Rees BI, Williams GT, Gallimore AM, Godkin AJ
PloS one 2006 Dec 27;1(1):e129
PloS one 2006 Dec 27;1(1):e129
The apoptotic-cell receptor CR3, but not alphavbeta5, is a regulator of human dendritic-cell immunostimulatory function.
Skoberne M, Somersan S, Almodovar W, Truong T, Petrova K, Henson PM, Bhardwaj N
Blood 2006 Aug 1;108(3):947-55
Blood 2006 Aug 1;108(3):947-55
Antagonists and non-toxic variants of the dominant wheat gliadin T cell epitope in coeliac disease.
Anderson RP, van Heel DA, Tye-Din JA, Jewell DP, Hill AV
Gut 2006 Apr;55(4):485-91
Gut 2006 Apr;55(4):485-91
Identification of a new HLA-A2-restricted T-cell epitope within HM1.24 as immunotherapy target for multiple myeloma.
Hundemer M, Schmidt S, Condomines M, Lupu A, Hose D, Moos M, Cremer F, Kleist C, Terness P, Belle S, Ho AD, Goldschmidt H, Klein B, Christensen O
Experimental hematology 2006 Apr;34(4):486-96
Experimental hematology 2006 Apr;34(4):486-96
Evaluation of adenovirus vectors containing serotype 35 fibers for vaccination.
DiPaolo N, Ni S, Gaggar A, Strauss R, Tuve S, Li ZY, Stone D, Shayakhmetov D, Kiviat N, Touré P, Sow S, Horvat B, Lieber A
Molecular therapy : the journal of the American Society of Gene Therapy 2006 Apr;13(4):756-65
Molecular therapy : the journal of the American Society of Gene Therapy 2006 Apr;13(4):756-65
CTL epitope distribution patterns in the Gag and Nef proteins of HIV-1 from subtype A infected subjects in Kenya: use of multiple peptide sets increases the detectable breadth of the CTL response.
Currier JR, Visawapoka U, Tovanabutra S, Mason CJ, Birx DL, McCutchan FE, Cox JH
BMC immunology 2006 Apr 18;7:8
BMC immunology 2006 Apr 18;7:8
Peripheral blood but not synovial fluid natural killer T cells are biased towards a Th1-like phenotype in rheumatoid arthritis.
Linsen L, Thewissen M, Baeten K, Somers V, Geusens P, Raus J, Stinissen P
Arthritis research & therapy 2005;7(3):R493-502
Arthritis research & therapy 2005;7(3):R493-502
Sustained CD8+ T-cell responses induced after acute parvovirus B19 infection in humans.
Norbeck O, Isa A, Pöhlmann C, Broliden K, Kasprowicz V, Bowness P, Klenerman P, Tolfvenstam T
Journal of virology 2005 Sep;79(18):12117-21
Journal of virology 2005 Sep;79(18):12117-21
Broad cross-clade T-cell responses to gag in individuals infected with human immunodeficiency virus type 1 non-B clades (A to G): importance of HLA anchor residue conservation.
Geels MJ, Dubey SA, Anderson K, Baan E, Bakker M, Pollakis G, Paxton WA, Shiver JW, Goudsmit J
Journal of virology 2005 Sep;79(17):11247-58
Journal of virology 2005 Sep;79(17):11247-58
Functional constraints of influenza A virus epitopes limit escape from cytotoxic T lymphocytes.
Berkhoff EG, de Wit E, Geelhoed-Mieras MM, Boon AC, Symons J, Fouchier RA, Osterhaus AD, Rimmelzwaan GF
Journal of virology 2005 Sep;79(17):11239-46
Journal of virology 2005 Sep;79(17):11239-46
Pulmonary interleukin-23 gene delivery increases local T-cell immunity and controls growth of Mycobacterium tuberculosis in the lungs.
Happel KI, Lockhart EA, Mason CM, Porretta E, Keoshkerian E, Odden AR, Nelson S, Ramsay AJ
Infection and immunity 2005 Sep;73(9):5782-8
Infection and immunity 2005 Sep;73(9):5782-8
Nickel elicits concomitant and correlated in vitro production of Th1-, Th2-type and regulatory cytokines in subjects with contact allergy to nickel.
Minang JT, Troye-Blomberg M, Lundeberg L, Ahlborg N
Scandinavian journal of immunology 2005 Sep;62(3):289-96
Scandinavian journal of immunology 2005 Sep;62(3):289-96
Modified vaccinia Ankara expressing HIVA antigen stimulates HIV-1-specific CD8 T cells in ELISpot assays of HIV-1 exposed infants.
Slyker JA, Lohman BL, Mbori-Ngacha DA, Reilly M, Wee EG, Dong T, McMichael AJ, Rowland-Jones SL, Hanke T, John-Stewart G
Vaccine 2005 Sep 7;23(38):4711-9
Vaccine 2005 Sep 7;23(38):4711-9
T cell reactivity to P0, P2, PMP-22, and myelin basic protein in patients with Guillain-Barre syndrome and chronic inflammatory demyelinating polyradiculoneuropathy.
Csurhes PA, Sullivan AA, Green K, Pender MP, McCombe PA
Journal of neurology, neurosurgery, and psychiatry 2005 Oct;76(10):1431-9
Journal of neurology, neurosurgery, and psychiatry 2005 Oct;76(10):1431-9
Reduced frequency of FOXP3+ CD4+CD25+ regulatory T cells in patients with chronic graft-versus-host disease.
Zorn E, Kim HT, Lee SJ, Floyd BH, Litsa D, Arumugarajah S, Bellucci R, Alyea EP, Antin JH, Soiffer RJ, Ritz J
Blood 2005 Oct 15;106(8):2903-11
Blood 2005 Oct 15;106(8):2903-11
Cytokine serum levels in patients infected by human immunodeficiency virus with and without Trypanosoma cruzi coinfection.
Rodrigues DB, Correia D, Marra MD, Giraldo LE, Lages-Silva E, Silva-Vergara ML, Barata CH, Rodrigues Junior V
Revista da Sociedade Brasileira de Medicina Tropical 2005 Nov-Dec;38(6):483-7
Revista da Sociedade Brasileira de Medicina Tropical 2005 Nov-Dec;38(6):483-7
The immunogenicity of a viral cytotoxic T cell epitope is controlled by its MHC-bound conformation.
Tynan FE, Elhassen D, Purcell AW, Burrows JM, Borg NA, Miles JJ, Williamson NA, Green KJ, Tellam J, Kjer-Nielsen L, McCluskey J, Rossjohn J, Burrows SR
The Journal of experimental medicine 2005 Nov 7;202(9):1249-60
The Journal of experimental medicine 2005 Nov 7;202(9):1249-60
Live attenuated yellow fever 17D infects human DCs and allows for presentation of endogenous and recombinant T cell epitopes.
Barba-Spaeth G, Longman RS, Albert ML, Rice CM
The Journal of experimental medicine 2005 Nov 7;202(9):1179-84
The Journal of experimental medicine 2005 Nov 7;202(9):1179-84
Enzyme-linked immunospot and tuberculin skin testing to detect latent tuberculosis infection.
Shams H, Weis SE, Klucar P, Lalvani A, Moonan PK, Pogoda JM, Ewer K, Barnes PF
American journal of respiratory and critical care medicine 2005 Nov 1;172(9):1161-8
American journal of respiratory and critical care medicine 2005 Nov 1;172(9):1161-8
Early T-cell responses to dengue virus epitopes in Vietnamese adults with secondary dengue virus infections.
Simmons CP, Dong T, Chau NV, Dung NT, Chau TN, Thao le TT, Dung NT, Hien TT, Rowland-Jones S, Farrar J
Journal of virology 2005 May;79(9):5665-75
Journal of virology 2005 May;79(9):5665-75
Cross-reactive cytotoxic T lymphocytes against human immunodeficiency virus type 1 protease and gamma interferon-inducible protein 30.
Mason RD, Bowmer MI, Howley CM, Grant MD
Journal of virology 2005 May;79(9):5529-36
Journal of virology 2005 May;79(9):5529-36
Efficient Ex vivo stimulation of Mycobacterium tuberculosis-specific T cells by genetically detoxified Bordetella pertussis adenylate cyclase antigen toxoids.
Wilkinson KA, Simsova M, Schölvinck E, Sebo P, Leclerc C, Vordermeier HM, Dickson SJ, Brown JR, Davidson RN, Pasvol G, Levin M, Wilkinson RJ
Infection and immunity 2005 May;73(5):2991-8
Infection and immunity 2005 May;73(5):2991-8
Schistosoma infection inhibits cellular immune responses to core HCV peptides.
Farid A, Al-Sherbiny M, Osman A, Mohamed N, Saad A, Shata MT, Lee DH, Prince AM, Strickland GT
Parasite immunology 2005 May;27(5):189-96
Parasite immunology 2005 May;27(5):189-96
Hepatitis B surface antigen presentation and HLA-DRB1*- lessons from twins and peptide binding studies.
Kruger A, Adams P, Hammer J, Böcher WO, Schneider PM, Rittner C, Hoehler T
Clinical and experimental immunology 2005 May;140(2):325-32
Clinical and experimental immunology 2005 May;140(2):325-32
Identification of a new HLA-A*0201-restricted CD8+ T cell epitope from hepatocellular carcinoma-associated antigen HCA587.
Li B, Wang Y, Chen J, Wu H, Chen W
Clinical and experimental immunology 2005 May;140(2):310-9
Clinical and experimental immunology 2005 May;140(2):310-9
Oral immune regulation using colitis extracted proteins for treatment of Crohn's disease: results of a phase I clinical trial.
Israeli E, Goldin E, Shibolet O, Klein A, Hemed N, Engelhardt D, Rabbani E, Ilan Y
World journal of gastroenterology 2005 May 28;11(20):3105-11
World journal of gastroenterology 2005 May 28;11(20):3105-11
Sustained expansion of NKT cells and antigen-specific T cells after injection of alpha-galactosyl-ceramide loaded mature dendritic cells in cancer patients.
Chang DH, Osman K, Connolly J, Kukreja A, Krasovsky J, Pack M, Hutchinson A, Geller M, Liu N, Annable R, Shay J, Kirchhoff K, Nishi N, Ando Y, Hayashi K, Hassoun H, Steinman RM, Dhodapkar MV
The Journal of experimental medicine 2005 May 2;201(9):1503-17
The Journal of experimental medicine 2005 May 2;201(9):1503-17
Simultaneous assessment of cytotoxic T lymphocyte responses against multiple viral infections by combined usage of optimal epitope matrices, anti- CD3 mAb T-cell expansion and "RecycleSpot".
Bihl FK, Loggi E, Chisholm JV 3rd, Hewitt HS, Henry LM, Linde C, Suscovich TJ, Wong JT, Frahm N, Andreone P, Brander C
Journal of translational medicine 2005 May 11;3(1):20
Journal of translational medicine 2005 May 11;3(1):20
Processing and presentation of exogenous HLA class I peptides by dendritic cells from human immunodeficiency virus type 1-infected persons.
Huang XL, Fan Z, Colleton BA, Buchli R, Li H, Hildebrand WH, Rinaldo CR Jr
Journal of virology 2005 Mar;79(5):3052-62
Journal of virology 2005 Mar;79(5):3052-62
MyD88 expression is required for efficient cross-presentation of viral antigens from infected cells.
Chen M, Barnfield C, Näslund TI, Fleeton MN, Liljeström P
Journal of virology 2005 Mar;79(5):2964-72
Journal of virology 2005 Mar;79(5):2964-72
Vaccination of metastatic melanoma patients with autologous dendritic cell (DC) derived-exosomes: results of thefirst phase I clinical trial.
Escudier B, Dorval T, Chaput N, André F, Caby MP, Novault S, Flament C, Leboulaire C, Borg C, Amigorena S, Boccaccio C, Bonnerot C, Dhellin O, Movassagh M, Piperno S, Robert C, Serra V, Valente N, Le Pecq JB, Spatz A, Lantz O, Tursz T, Angevin E, Zitvogel L
Journal of translational medicine 2005 Mar 2;3(1):10
Journal of translational medicine 2005 Mar 2;3(1):10
Repertoire, diversity, and differentiation of specific CD8 T cells are associated with immune protection against human cytomegalovirus disease.
Sacre K, Carcelain G, Cassoux N, Fillet AM, Costagliola D, Vittecoq D, Salmon D, Amoura Z, Katlama C, Autran B
The Journal of experimental medicine 2005 Jun 20;201(12):1999-2010
The Journal of experimental medicine 2005 Jun 20;201(12):1999-2010
Recognition of six-transmembrane epithelial antigen of the prostate-expressing tumor cells by peptide antigen-induced cytotoxic T lymphocytes.
Rodeberg DA, Nuss RA, Elsawa SF, Celis E
Clinical cancer research : an official journal of the American Association for Cancer Research 2005 Jun 15;11(12):4545-52
Clinical cancer research : an official journal of the American Association for Cancer Research 2005 Jun 15;11(12):4545-52
Longitudinal assessment of human immunodeficiency virus type 1 (HIV-1)-specific gamma interferon responses during the first year of life in HIV-1-infected infants.
Lohman BL, Slyker JA, Richardson BA, Farquhar C, Mabuka JM, Crudder C, Dong T, Obimbo E, Mbori-Ngacha D, Overbaugh J, Rowland-Jones S, John-Stewart G
Journal of virology 2005 Jul;79(13):8121-30
Journal of virology 2005 Jul;79(13):8121-30
Human immunodeficiency virus type 1 Vpr impairs dendritic cell maturation and T-cell activation: implications for viral immune escape.
Majumder B, Janket ML, Schafer EA, Schaubert K, Huang XL, Kan-Mitchell J, Rinaldo CR Jr, Ayyavoo V
Journal of virology 2005 Jul;79(13):7990-8003
Journal of virology 2005 Jul;79(13):7990-8003
Innate immune responses in Lyme borreliosis: enhanced tumour necrosis factor-alpha and interleukin-12 in asymptomatic individuals in response to live spirochetes.
Sjöwall J, Carlsson A, Vaarala O, Bergström S, Ernerudh J, Forsberg P, Ekerfelt C
Clinical and experimental immunology 2005 Jul;141(1):89-98
Clinical and experimental immunology 2005 Jul;141(1):89-98
T-cell responses to human papillomavirus type 16 among women with different grades of cervical neoplasia.
Steele JC, Mann CH, Rookes S, Rollason T, Murphy D, Freeth MG, Gallimore PH, Roberts S
British journal of cancer 2005 Jul 25;93(2):248-59
British journal of cancer 2005 Jul 25;93(2):248-59
The bisphosphonate acute phase response: rapid and copious production of proinflammatory cytokines by peripheral blood gd T cells in response to aminobisphosphonates is inhibited by statins.
Hewitt RE, Lissina A, Green AE, Slay ES, Price DA, Sewell AK
Clinical and experimental immunology 2005 Jan;139(1):101-11
Clinical and experimental immunology 2005 Jan;139(1):101-11
Clinical response in Japanese metastatic melanoma patients treated with peptide cocktail-pulsed dendritic cells.
Akiyama Y, Tanosaki R, Inoue N, Shimada M, Hotate Y, Yamamoto A, Yamazaki N, Kawashima I, Nukaya I, Takesako K, Maruyama K, Takaue Y, Yamaguchi K
Journal of translational medicine 2005 Jan 28;3(1):4
Journal of translational medicine 2005 Jan 28;3(1):4
T cell response to Hu-D peptides in patients with anti-Hu syndrome.
Rousseau A, Benyahia B, Dalmau J, Connan F, Guillet JG, Delattre JY, Choppin J
Journal of neuro-oncology 2005 Feb;71(3):231-6
Journal of neuro-oncology 2005 Feb;71(3):231-6
CD8+ immunodominance among Epstein-Barr virus lytic cycle antigens directly reflects the efficiency of antigen presentation in lytically infected cells.
Pudney VA, Leese AM, Rickinson AB, Hislop AD
The Journal of experimental medicine 2005 Feb 7;201(3):349-60
The Journal of experimental medicine 2005 Feb 7;201(3):349-60
Selective blockade of inhibitory Fcgamma receptor enables human dendritic cell maturation with IL-12p70 production and immunity to antibody-coated tumor cells.
Dhodapkar KM, Kaufman JL, Ehlers M, Banerjee DK, Bonvini E, Koenig S, Steinman RM, Ravetch JV, Dhodapkar MV
Proceedings of the National Academy of Sciences of the United States of America 2005 Feb 22;102(8):2910-5
Proceedings of the National Academy of Sciences of the United States of America 2005 Feb 22;102(8):2910-5
Antigen expression kinetics and immune responses of mice immunized with noninfectious simian-human immunodeficiency virus DNA.
Hegde R, Liu Z, Mackay G, Smith M, Chebloune Y, Narayan O, Singh DK
Journal of virology 2005 Dec;79(23):14688-97
Journal of virology 2005 Dec;79(23):14688-97
HLA-DR+ immature cells exhibit reduced antigen-presenting cell function but respond to CD40 stimulation.
Pinzon-Charry A, Maxwell T, Prato S, Furnival C, Schmidt C, López JA
Neoplasia (New York, N.Y.) 2005 Dec;7(12):1123-32
Neoplasia (New York, N.Y.) 2005 Dec;7(12):1123-32
A population of HLA-DR+ immature cells accumulates in the blood dendritic cell compartment of patients with different types of cancer.
Pinzon-Charry A, Ho CS, Laherty R, Maxwell T, Walker D, Gardiner RA, O'Connor L, Pyke C, Schmidt C, Furnival C, López JA
Neoplasia (New York, N.Y.) 2005 Dec;7(12):1112-22
Neoplasia (New York, N.Y.) 2005 Dec;7(12):1112-22
Dendritic cell immunizations alone or combined with low doses of interleukin-2 induce specific immune responses in melanoma patients.
Escobar A, López M, Serrano A, Ramirez M, Pérez C, Aguirre A, González R, Alfaro J, Larrondo M, Fodor M, Ferrada C, Salazar-Onfray F
Clinical and experimental immunology 2005 Dec;142(3):555-68
Clinical and experimental immunology 2005 Dec;142(3):555-68
Cross-reactive influenza virus-specific CD8+ T cells contribute to lymphoproliferation in Epstein-Barr virus-associated infectious mononucleosis.
Clute SC, Watkin LB, Cornberg M, Naumov YN, Sullivan JL, Luzuriaga K, Welsh RM, Selin LK
The Journal of clinical investigation 2005 Dec;115(12):3602-12
The Journal of clinical investigation 2005 Dec;115(12):3602-12
HLA-B63 presents HLA-B57/B58-restricted cytotoxic T-lymphocyte epitopes and is associated with low human immunodeficiency virus load.
Frahm N, Adams S, Kiepiela P, Linde CH, Hewitt HS, Lichterfeld M, Sango K, Brown NV, Pae E, Wurcel AG, Altfeld M, Feeney ME, Allen TM, Roach T, St John MA, Daar ES, Rosenberg E, Korber B, Marincola F, Walker BD, Goulder PJ, Brander C
Journal of virology 2005 Aug;79(16):10218-25
Journal of virology 2005 Aug;79(16):10218-25
Cytokine expression in pediatric Helicobacter pylori infection.
Lopes AI, Quiding-Jarbrink M, Palha A, Ruivo J, Monteiro L, Oleastro M, Santos A, Fernandes A
Clinical and diagnostic laboratory immunology 2005 Aug;12(8):994-1002
Clinical and diagnostic laboratory immunology 2005 Aug;12(8):994-1002
Human immunodeficiency virus (HIV)-specific gamma interferon secretion directed against all expressed HIV genes: relationship to rate of CD4 decline.
Peretz Y, Alter G, Boisvert MP, Hatzakis G, Tsoukas CM, Bernard NF
Journal of virology 2005 Apr;79(8):4908-17
Journal of virology 2005 Apr;79(8):4908-17
Human immunodeficiency virus-specific responses in adult Ugandans: patterns of cross-clade recognition.
Barugahare B, Baker C, K'Aluoch O, Donovan R, Elrefaei M, Eggena M, Jones N, Mutalya S, Kityo C, Mugyenyi P, Cao H
Journal of virology 2005 Apr;79(7):4132-9
Journal of virology 2005 Apr;79(7):4132-9
Mycobacterium tuberculosis genome-wide screen exposes multiple CD8 T cell epitopes.
Hammond AS, Klein MR, Corrah T, Fox A, Jaye A, McAdam KP, Brookes RH
Clinical and experimental immunology 2005 Apr;140(1):109-16
Clinical and experimental immunology 2005 Apr;140(1):109-16
CD25brightCD4+ regulatory T cells are enriched in inflamed joints of patients with chronic rheumatic disease.
Cao D, van Vollenhoven R, Klareskog L, Trollmo C, Malmström V
Arthritis research & therapy 2004;6(4):R335-46
Arthritis research & therapy 2004;6(4):R335-46
Impaired IFN-gamma production by viral immunodominant peptide-specific tetramer+ CD8+ T cells in HIV-1 infected patients is not secondary to HAART.
Onlamoon N, Pattanapanyasat K, Ansari AA
Clinical & developmental immunology 2004 Sep-Dec;11(3-4):287-98
Clinical & developmental immunology 2004 Sep-Dec;11(3-4):287-98
A hairpin turn in a class II MHC-bound peptide orients residues outside the binding groove for T cell recognition.
Zavala-Ruiz Z, Strug I, Walker BD, Norris PJ, Stern LJ
Proceedings of the National Academy of Sciences of the United States of America 2004 Sep 7;101(36):13279-84
Proceedings of the National Academy of Sciences of the United States of America 2004 Sep 7;101(36):13279-84
Loss of HIV-1-specific CD8+ T cell proliferation after acute HIV-1 infection and restoration by vaccine-induced HIV-1-specific CD4+ T cells.
Lichterfeld M, Kaufmann DE, Yu XG, Mui SK, Addo MM, Johnston MN, Cohen D, Robbins GK, Pae E, Alter G, Wurcel A, Stone D, Rosenberg ES, Walker BD, Altfeld M
The Journal of experimental medicine 2004 Sep 20;200(6):701-12
The Journal of experimental medicine 2004 Sep 20;200(6):701-12
IFN-gamma enables cross-presentation of exogenous protein antigen in human Langerhans cells by potentiating maturation.
Matsuo M, Nagata Y, Sato E, Atanackovic D, Valmori D, Chen YT, Ritter G, Mellman I, Old LJ, Gnjatic S
Proceedings of the National Academy of Sciences of the United States of America 2004 Oct 5;101(40):14467-72
Proceedings of the National Academy of Sciences of the United States of America 2004 Oct 5;101(40):14467-72
Human immunodeficiency virus type 1 (HIV-1)-specific CD4+ T cells that proliferate in vitro detected in samples from most viremic subjects and inversely associated with plasma HIV-1 levels.
Boritz E, Palmer BE, Wilson CC
Journal of virology 2004 Nov;78(22):12638-46
Journal of virology 2004 Nov;78(22):12638-46
Multispecific T cell response and negative HCV RNA tests during acute HCV infection are early prognostic factors of spontaneous clearance.
Spada E, Mele A, Berton A, Ruggeri L, Ferrigno L, Garbuglia AR, Perrone MP, Girelli G, Del Porto P, Piccolella E, Mondelli MU, Amoroso P, Cortese R, Nicosia A, Vitelli A, Folgori A
Gut 2004 Nov;53(11):1673-81
Gut 2004 Nov;53(11):1673-81
Detecting specific cytotoxic T lymphocytes against SARS-coronavirus with DimerX HLA-A2:Ig fusion protein.
Wang YD, Chen WF
Clinical immunology (Orlando, Fla.) 2004 Nov;113(2):151-4
Clinical immunology (Orlando, Fla.) 2004 Nov;113(2):151-4
Limited durability of viral control following treated acute HIV infection.
Kaufmann DE, Lichterfeld M, Altfeld M, Addo MM, Johnston MN, Lee PK, Wagner BS, Kalife ET, Strick D, Rosenberg ES, Walker BD
PLoS medicine 2004 Nov;1(2):e36
PLoS medicine 2004 Nov;1(2):e36
A randomised, double-blind, controlled vaccine efficacy trial of DNA/MVA ME-TRAP against malaria infection in Gambian adults.
Moorthy VS, Imoukhuede EB, Milligan P, Bojang K, Keating S, Kaye P, Pinder M, Gilbert SC, Walraven G, Greenwood BM, Hill AS
PLoS medicine 2004 Nov;1(2):e33
PLoS medicine 2004 Nov;1(2):e33
Determinants of human immunodeficiency virus type 1 escape from the primary CD8+ cytotoxic T lymphocyte response.
Jones NA, Wei X, Flower DR, Wong M, Michor F, Saag MS, Hahn BH, Nowak MA, Shaw GM, Borrow P
The Journal of experimental medicine 2004 Nov 15;200(10):1243-56
The Journal of experimental medicine 2004 Nov 15;200(10):1243-56
Evaluation of T-cell responses to novel RD1- and RD2-encoded Mycobacterium tuberculosis gene products for specific detection of human tuberculosis infection.
Liu XQ, Dosanjh D, Varia H, Ewer K, Cockle P, Pasvol G, Lalvani A
Infection and immunity 2004 May;72(5):2574-81
Infection and immunity 2004 May;72(5):2574-81
Gender-related cytokine patterns in sera of schistosomiasis patients with Symmers' fibrosis.
Silva-Teixeira DN, Contigli C, Lambertucci JR, Serufo JC, Rodrigues V Jr
Clinical and diagnostic laboratory immunology 2004 May;11(3):627-30
Clinical and diagnostic laboratory immunology 2004 May;11(3):627-30
CD8+ T lymphocyte responses target functionally important regions of Protease and Integrase in HIV-1 infected subjects.
Rodriguez WR, Addo MM, Rathod A, Fitzpatrick CA, Yu XG, Perkins B, Rosenberg ES, Altfeld M, Walker BD
Journal of translational medicine 2004 May 21;2(1):15
Journal of translational medicine 2004 May 21;2(1):15
Consistent cytotoxic-T-lymphocyte targeting of immunodominant regions in human immunodeficiency virus across multiple ethnicities.
Frahm N, Korber BT, Adams CM, Szinger JJ, Draenert R, Addo MM, Feeney ME, Yusim K, Sango K, Brown NV, SenGupta D, Piechocka-Trocha A, Simonis T, Marincola FM, Wurcel AG, Stone DR, Russell CJ, Adolf P, Cohen D, Roach T, StJohn A, Khatri A, Davis K, Mullins J, Goulder PJ, Walker BD, Brander C
Journal of virology 2004 Mar;78(5):2187-200
Journal of virology 2004 Mar;78(5):2187-200
T-cell epitopes in severe acute respiratory syndrome (SARS) coronavirus spike protein elicit a specific T-cell immune response in patients who recover from SARS.
Wang YD, Sin WY, Xu GB, Yang HH, Wong TY, Pang XW, He XY, Zhang HG, Ng JN, Cheng CS, Yu J, Meng L, Yang RF, Lai ST, Guo ZH, Xie Y, Chen WF
Journal of virology 2004 Jun;78(11):5612-8
Journal of virology 2004 Jun;78(11):5612-8
Toll-like receptor 4 expression and cytokine responses in the human urinary tract mucosa.
Samuelsson P, Hang L, Wullt B, Irjala H, Svanborg C
Infection and immunity 2004 Jun;72(6):3179-86
Infection and immunity 2004 Jun;72(6):3179-86
Recognition of nonpeptide antigens by human V gamma 9V delta 2 T cells requires contact with cells of human origin.
Green AE, Lissina A, Hutchinson SL, Hewitt RE, Temple B, James D, Boulter JM, Price DA, Sewell AK
Clinical and experimental immunology 2004 Jun;136(3):472-82
Clinical and experimental immunology 2004 Jun;136(3):472-82
Individual RD1-region genes are required for export of ESAT-6/CFP-10 and for virulence of Mycobacterium tuberculosis.
Guinn KM, Hickey MJ, Mathur SK, Zakel KL, Grotzke JE, Lewinsohn DM, Smith S, Sherman DR
Molecular microbiology 2004 Jan;51(2):359-70
Molecular microbiology 2004 Jan;51(2):359-70
Identification of a common HLA-DP4-restricted T-cell epitope in the conserved region of the respiratory syncytial virus G protein.
de Waal L, Yüksel S, Brandenburg AH, Langedijk JP, Sintnicolaas K, Verjans GM, Osterhaus AD, de Swart RL
Journal of virology 2004 Feb;78(4):1775-81
Journal of virology 2004 Feb;78(4):1775-81
IL-12 enhances the generation of tumour antigen-specific Th1 CD4 T cells during ex vivo expansion.
Knutson KL, Disis ML
Clinical and experimental immunology 2004 Feb;135(2):322-9
Clinical and experimental immunology 2004 Feb;135(2):322-9
Cellular immunity induced by the recombinant Plasmodium falciparum malaria vaccine, RTS,S/AS02, in semi-immune adults in The Gambia.
Pinder M, Reece WH, Plebanski M, Akinwunmi P, Flanagan KL, Lee EA, Doherty T, Milligan P, Jaye A, Tornieporth N, Ballou R, McAdam KP, Cohen J, Hill AV
Clinical and experimental immunology 2004 Feb;135(2):286-93
Clinical and experimental immunology 2004 Feb;135(2):286-93
Comparison of human immunodeficiency virus (HIV)-specific T-cell responses in HIV-1- and HIV-2-infected individuals in Senegal.
Zheng NN, Kiviat NB, Sow PS, Hawes SE, Wilson A, Diallo-Agne H, Critchlow CW, Gottlieb GS, Musey L, McElrath MJ
Journal of virology 2004 Dec;78(24):13934-42
Journal of virology 2004 Dec;78(24):13934-42
Functional regulatory immune responses against human cartilage glycoprotein-39 in health vs. proinflammatory responses in rheumatoid arthritis.
van Bilsen JH, van Dongen H, Lard LR, van der Voort EI, Elferink DG, Bakker AM, Miltenburg AM, Huizinga TW, de Vries RR, Toes RE
Proceedings of the National Academy of Sciences of the United States of America 2004 Dec 7;101(49):17180-5
Proceedings of the National Academy of Sciences of the United States of America 2004 Dec 7;101(49):17180-5
T cell cross-reactivity and conformational changes during TCR engagement.
Lee JK, Stewart-Jones G, Dong T, Harlos K, Di Gleria K, Dorrell L, Douek DC, van der Merwe PA, Jones EY, McMichael AJ
The Journal of experimental medicine 2004 Dec 6;200(11):1455-66
The Journal of experimental medicine 2004 Dec 6;200(11):1455-66
Cytotoxic T lymphocyte therapy for Epstein-Barr virus+ Hodgkin's disease.
Bollard CM, Aguilar L, Straathof KC, Gahn B, Huls MH, Rousseau A, Sixbey J, Gresik MV, Carrum G, Hudson M, Dilloo D, Gee A, Brenner MK, Rooney CM, Heslop HE
The Journal of experimental medicine 2004 Dec 20;200(12):1623-33
The Journal of experimental medicine 2004 Dec 20;200(12):1623-33
Frequent transmission of cytotoxic-T-lymphocyte escape mutants of human immunodeficiency virus type 1 in the highly HLA-A24-positive Japanese population.
Furutsuki T, Hosoya N, Kawana-Tachikawa A, Tomizawa M, Odawara T, Goto M, Kitamura Y, Nakamura T, Kelleher AD, Cooper DA, Iwamoto A
Journal of virology 2004 Aug;78(16):8437-45
Journal of virology 2004 Aug;78(16):8437-45
Increased expression of mRNA encoding interleukin (IL)-4 and its splice variant IL-4delta2 in cells from contacts of Mycobacterium tuberculosis, in the absence of in vitro stimulation.
Fletcher HA, Owiafe P, Jeffries D, Hill P, Rook GA, Zumla A, Doherty TM, Brookes RH, Vacsel Study Group
Immunology 2004 Aug;112(4):669-73
Immunology 2004 Aug;112(4):669-73
Mesothelin-specific CD8(+) T cell responses provide evidence of in vivo cross-priming by antigen-presenting cells in vaccinated pancreatic cancer patients.
Thomas AM, Santarsiero LM, Lutz ER, Armstrong TD, Chen YC, Huang LQ, Laheru DA, Goggins M, Hruban RH, Jaffee EM
The Journal of experimental medicine 2004 Aug 2;200(3):297-306
The Journal of experimental medicine 2004 Aug 2;200(3):297-306
A phase I trial of DNA vaccination with a plasmid expressing prostate-specific antigen in patients with hormone-refractory prostate cancer.
Pavlenko M, Roos AK, Lundqvist A, Palmborg A, Miller AM, Ozenci V, Bergman B, Egevad L, Hellström M, Kiessling R, Masucci G, Wersäll P, Nilsson S, Pisa P
British journal of cancer 2004 Aug 16;91(4):688-94
British journal of cancer 2004 Aug 16;91(4):688-94
Hierarchical targeting of subtype C human immunodeficiency virus type 1 proteins by CD8+ T cells: correlation with viral load.
Masemola A, Mashishi T, Khoury G, Mohube P, Mokgotho P, Vardas E, Colvin M, Zijenah L, Katzenstein D, Musonda R, Allen S, Kumwenda N, Taha T, Gray G, McIntyre J, Karim SA, Sheppard HW, Gray CM, HIVNET 028 Study Team
Journal of virology 2004 Apr;78(7):3233-43
Journal of virology 2004 Apr;78(7):3233-43
Minor histocompatibility antigen DBY elicits a coordinated B and T cell response after allogeneic stem cell transplantation.
Zorn E, Miklos DB, Floyd BH, Mattes-Ritz A, Guo L, Soiffer RJ, Antin JH, Ritz J
The Journal of experimental medicine 2004 Apr 19;199(8):1133-42
The Journal of experimental medicine 2004 Apr 19;199(8):1133-42
High levels of interleukin-1 in patients with endemic pemphigus foliaceus.
Rocha-Rodrigues DB, Paschoini G, Pereira SA, dos Reis MA, Teixeira Vde P, Rodrigues Júnior V
Clinical and diagnostic laboratory immunology 2003 Sep;10(5):741-3
Clinical and diagnostic laboratory immunology 2003 Sep;10(5):741-3
Long-term specific immune responses induced in humans by a human immunodeficiency virus type 1 lipopeptide vaccine: characterization of CD8+-T-cell epitopes recognized.
Gahéry-Ségard H, Pialoux G, Figueiredo S, Igéa C, Surenaud M, Gaston J, Gras-Masse H, Lévy JP, Guillet JG
Journal of virology 2003 Oct;77(20):11220-31
Journal of virology 2003 Oct;77(20):11220-31
Productive infection maintains a dynamic steady state of residual viremia in human immunodeficiency virus type 1-infected persons treated with suppressive antiretroviral therapy for five years.
Havlir DV, Strain MC, Clerici M, Ignacio C, Trabattoni D, Ferrante P, Wong JK
Journal of virology 2003 Oct;77(20):11212-9
Journal of virology 2003 Oct;77(20):11212-9
Yeast-derived human immunodeficiency virus type 1 p55(gag) virus-like particles activate dendritic cells (DCs) and induce perforin expression in Gag-specific CD8(+) T cells by cross-presentation of DCs.
Tsunetsugu-Yokota Y, Morikawa Y, Isogai M, Kawana-Tachikawa A, Odawara T, Nakamura T, Grassi F, Autran B, Iwamoto A
Journal of virology 2003 Oct;77(19):10250-9
Journal of virology 2003 Oct;77(19):10250-9
Over-expression of interleukin 10 in mucosal T cells of patients with active ulcerative colitis.
Melgar S, Yeung MM, Bas A, Forsberg G, Suhr O, Oberg A, Hammarstrom S, Danielsson A, Hammarstrom ML
Clinical and experimental immunology 2003 Oct;134(1):127-37
Clinical and experimental immunology 2003 Oct;134(1):127-37
Vaccination of recurrent glioma patients with tumour lysate-pulsed dendritic cells elicits immune responses: results of a clinical phase I/II trial.
Yamanaka R, Abe T, Yajima N, Tsuchiya N, Homma J, Kobayashi T, Narita M, Takahashi M, Tanaka R
British journal of cancer 2003 Oct 6;89(7):1172-9
British journal of cancer 2003 Oct 6;89(7):1172-9
Ex vivo profiling of CD8+-T-cell responses to human cytomegalovirus reveals broad and multispecific reactivities in healthy virus carriers.
Elkington R, Walker S, Crough T, Menzies M, Tellam J, Bharadwaj M, Khanna R
Journal of virology 2003 May;77(9):5226-40
Journal of virology 2003 May;77(9):5226-40
Evaluation of amastigote reactive cells in human cutaneous leishmaniasis caused by Leishmania aethiopica.
Maasho K, McMahon-Pratt D, Raita J, Raud M, Britton S, Soong L, Akuffo H
Clinical and experimental immunology 2003 May;132(2):316-22
Clinical and experimental immunology 2003 May;132(2):316-22
Tolerogenic immunosuppression for organ transplantation.
Starzl TE, Murase N, Abu-Elmagd K, Gray EA, Shapiro R, Eghtesad B, Corry RJ, Jordan ML, Fontes P, Gayowski T, Bond G, Scantlebury VP, Potdar S, Randhawa P, Wu T, Zeevi A, Nalesnik MA, Woodward J, Marcos A, Trucco M, Demetris AJ, Fung JJ
Lancet (London, England) 2003 May 3;361(9368):1502-10
Lancet (London, England) 2003 May 3;361(9368):1502-10
Live Leishmania promastigotes can directly activate primary human natural killer cells to produce interferon-gamma.
Nylén S, Maasho K, Söderstrom K, Ilg T, Akuffo H
Clinical and experimental immunology 2003 Mar;131(3):457-67
Clinical and experimental immunology 2003 Mar;131(3):457-67
Melanoma inhibitor of apoptosis protein (ML-IAP) is a target for immune-mediated tumor destruction.
Schmollinger JC, Vonderheide RH, Hoar KM, Maecker B, Schultze JL, Hodi FS, Soiffer RJ, Jung K, Kuroda MJ, Letvin NL, Greenfield EA, Mihm M, Kutok JL, Dranoff G
Proceedings of the National Academy of Sciences of the United States of America 2003 Mar 18;100(6):3398-403
Proceedings of the National Academy of Sciences of the United States of America 2003 Mar 18;100(6):3398-403
Comprehensive analysis of human immunodeficiency virus type 1 (HIV-1)-specific gamma interferon-secreting CD8+ T cells in primary HIV-1 infection.
Cao J, McNevin J, Holte S, Fink L, Corey L, McElrath MJ
Journal of virology 2003 Jun;77(12):6867-78
Journal of virology 2003 Jun;77(12):6867-78
Mature CD8(+) T lymphocyte response to viral infection during fetal life.
Marchant A, Appay V, Van Der Sande M, Dulphy N, Liesnard C, Kidd M, Kaye S, Ojuola O, Gillespie GM, Vargas Cuero AL, Cerundolo V, Callan M, McAdam KP, Rowland-Jones SL, Donner C, McMichael AJ, Whittle H
The Journal of clinical investigation 2003 Jun;111(11):1747-55
The Journal of clinical investigation 2003 Jun;111(11):1747-55
Comprehensive screening reveals strong and broadly directed human immunodeficiency virus type 1-specific CD8 responses in perinatally infected children.
Feeney ME, Roosevelt KA, Tang Y, Pfafferott KJ, McIntosh K, Burchett SK, Mao C, Walker BD, Goulder PJ
Journal of virology 2003 Jul;77(13):7492-501
Journal of virology 2003 Jul;77(13):7492-501
Ex vivo analysis of T-cell responses to Epstein-Barr virus-encoded oncogene latent membrane protein 1 reveals highly conserved epitope sequences in virus isolates from diverse geographic regions.
Duraiswamy J, Burrows JM, Bharadwaj M, Burrows SR, Cooper L, Pimtanothai N, Khanna R
Journal of virology 2003 Jul;77(13):7401-10
Journal of virology 2003 Jul;77(13):7401-10
Enhanced detection of human immunodeficiency virus type 1-specific T-cell responses to highly variable regions by using peptides based on autologous virus sequences.
Altfeld M, Addo MM, Shankarappa R, Lee PK, Allen TM, Yu XG, Rathod A, Harlow J, O'Sullivan K, Johnston MN, Goulder PJ, Mullins JI, Rosenberg ES, Brander C, Korber B, Walker BD
Journal of virology 2003 Jul;77(13):7330-40
Journal of virology 2003 Jul;77(13):7330-40
Respiratory syncytial virus nucleoprotein-specific cytotoxic T-cell epitopes in a South African population of diverse HLA types are conserved in circulating field strains.
Venter M, Rock M, Puren AJ, Tiemessen CT, Crowe JE Jr
Journal of virology 2003 Jul;77(13):7319-29
Journal of virology 2003 Jul;77(13):7319-29
Murine cytomegalovirus abortively infects human dendritic cells, leading to expression and presentation of virally vectored genes.
Wang X, Messerle M, Sapinoro R, Santos K, Hocknell PK, Jin X, Dewhurst S
Journal of virology 2003 Jul;77(13):7182-92
Journal of virology 2003 Jul;77(13):7182-92
Survey of naturally occurring CD4+ T cell responses against NY-ESO-1 in cancer patients: correlation with antibody responses.
Gnjatic S, Atanackovic D, Jäger E, Matsuo M, Selvakumar A, Altorki NK, Maki RG, Dupont B, Ritter G, Chen YT, Knuth A, Old LJ
Proceedings of the National Academy of Sciences of the United States of America 2003 Jul 22;100(15):8862-7
Proceedings of the National Academy of Sciences of the United States of America 2003 Jul 22;100(15):8862-7
Identification of immunodominant epitopes derived from the respiratory syncytial virus fusion protein that are recognized by human CD4 T cells.
van Bleek GM, Poelen MC, van der Most R, Brugghe HF, Timmermans HA, Boog CJ, Hoogerhout P, Otten HG, van Els CA
Journal of virology 2003 Jan;77(2):980-8
Journal of virology 2003 Jan;77(2):980-8
Association between virus-specific T-cell responses and plasma viral load in human immunodeficiency virus type 1 subtype C infection.
Novitsky V, Gilbert P, Peter T, McLane MF, Gaolekwe S, Rybak N, Thior I, Ndung'u T, Marlink R, Lee TH, Essex M
Journal of virology 2003 Jan;77(2):882-90
Journal of virology 2003 Jan;77(2):882-90
Avenin fails to induce a Th1 response in coeliac tissue following in vitro culture.
Kilmartin C, Lynch S, Abuzakouk M, Wieser H, Feighery C
Gut 2003 Jan;52(1):47-52
Gut 2003 Jan;52(1):47-52
T cell vaccination in multiple sclerosis patients with autologous CSF-derived activated T cells: results from a pilot study.
Van der Aa A, Hellings N, Medaer R, Gelin G, Palmers Y, Raus J, Stinissen P
Clinical and experimental immunology 2003 Jan;131(1):155-68
Clinical and experimental immunology 2003 Jan;131(1):155-68
Decreased epithelial cytokine responses in the duodenal mucosa of Helicobacter pylori-infected duodenal ulcer patients.
Strömberg E, Edebo A, Svennerholm AM, Lindholm C
Clinical and diagnostic laboratory immunology 2003 Jan;10(1):116-24
Clinical and diagnostic laboratory immunology 2003 Jan;10(1):116-24
Early induction and maintenance of Env-specific T-helper cells following human immunodeficiency virus type 1 infection.
Malhotra U, Holte S, Zhu T, Delpit E, Huntsberry C, Sette A, Shankarappa R, Maenza J, Corey L, McElrath MJ
Journal of virology 2003 Feb;77(4):2663-74
Journal of virology 2003 Feb;77(4):2663-74
Comprehensive epitope analysis of human immunodeficiency virus type 1 (HIV-1)-specific T-cell responses directed against the entire expressed HIV-1 genome demonstrate broadly directed responses, but no correlation to viral load.
Addo MM, Yu XG, Rathod A, Cohen D, Eldridge RL, Strick D, Johnston MN, Corcoran C, Wurcel AG, Fitzpatrick CA, Feeney ME, Rodriguez WR, Basgoz N, Draenert R, Stone DR, Brander C, Goulder PJ, Rosenberg ES, Altfeld M, Walker BD
Journal of virology 2003 Feb;77(3):2081-92
Journal of virology 2003 Feb;77(3):2081-92
HLA class II polymorphisms and susceptibility to recurrent respiratory papillomatosis.
Gelder CM, Williams OM, Hart KW, Wall S, Williams G, Ingrams D, Bull P, Bunce M, Welsh K, Marshall SE, Borysiewicz L
Journal of virology 2003 Feb;77(3):1927-39
Journal of virology 2003 Feb;77(3):1927-39
Identification of sequential viral escape mutants associated with altered T-cell responses in a human immunodeficiency virus type 1-infected individual.
Geels MJ, Cornelissen M, Schuitemaker H, Anderson K, Kwa D, Maas J, Dekker JT, Baan E, Zorgdrager F, van den Burg R, van Beelen M, Lukashov VV, Fu TM, Paxton WA, van der Hoek L, Dubey SA, Shiver JW, Goudsmit J
Journal of virology 2003 Dec;77(23):12430-40
Journal of virology 2003 Dec;77(23):12430-40
Vigorous but short-term gamma interferon T-cell responses against a dominant HLA-A*02-restricted measles virus epitope in patients with measles.
Jaye A, Herberts CA, Jallow S, Atabani S, Klein MR, Hoogerhout P, Kidd M, van Els CA, Whittle HC
Journal of virology 2003 Apr;77(8):5014-6
Journal of virology 2003 Apr;77(8):5014-6
Kaposi's sarcoma-associated herpesvirus cytotoxic T lymphocytes recognize and target Darwinian positively selected autologous K1 epitopes.
Stebbing J, Bourboulia D, Johnson M, Henderson S, Williams I, Wilder N, Tyrer M, Youle M, Imami N, Kobu T, Kuon W, Sieper J, Gotch F, Boshoff C
Journal of virology 2003 Apr;77(7):4306-14
Journal of virology 2003 Apr;77(7):4306-14
Identification of a novel human leucocyte antigen-A*01-restricted cytotoxic T-lymphocyte epitope in the respiratory syncytial virus fusion protein.
Rock MT, Crowe JE Jr
Immunology 2003 Apr;108(4):474-80
Immunology 2003 Apr;108(4):474-80
A balanced type 1/type 2 response is associated with long-term nonprogressive human immunodeficiency virus type 1 infection.
Imami N, Pires A, Hardy G, Wilson J, Gazzard B, Gotch F
Journal of virology 2002 Sep;76(18):9011-23
Journal of virology 2002 Sep;76(18):9011-23
Consistent patterns in the development and immunodominance of human immunodeficiency virus type 1 (HIV-1)-specific CD8+ T-cell responses following acute HIV-1 infection.
Yu XG, Addo MM, Rosenberg ES, Rodriguez WR, Lee PK, Fitzpatrick CA, Johnston MN, Strick D, Goulder PJ, Walker BD, Altfeld M
Journal of virology 2002 Sep;76(17):8690-701
Journal of virology 2002 Sep;76(17):8690-701
CD8(+) T cell responses against a dominant cryptic HLA-A2 epitope after NY-ESO-1 peptide immunization of cancer patients.
Gnjatic S, Jäger E, Chen W, Altorki NK, Matsuo M, Lee SY, Chen Q, Nagata Y, Atanackovic D, Chen YT, Ritter G, Cebon J, Knuth A, Old LJ
Proceedings of the National Academy of Sciences of the United States of America 2002 Sep 3;99(18):11813-8
Proceedings of the National Academy of Sciences of the United States of America 2002 Sep 3;99(18):11813-8
Disease-associated bias in T helper type 1 (Th1)/Th2 CD4(+) T cell responses against MAGE-6 in HLA-DRB10401(+) patients with renal cell carcinoma or melanoma.
Tatsumi T, Kierstead LS, Ranieri E, Gesualdo L, Schena FP, Finke JH, Bukowski RM, Mueller-Berghaus J, Kirkwood JM, Kwok WW, Storkus WJ
The Journal of experimental medicine 2002 Sep 2;196(5):619-28
The Journal of experimental medicine 2002 Sep 2;196(5):619-28
Study of antigen-processing steps reveals preferences explaining differential biological outcomes of two HLA-A2-restricted immunodominant epitopes from human immunodeficiency virus type 1.
Cohen WM, Bianco A, Connan F, Camoin L, Dalod M, Lauvau G, Ferriès E, Culmann-Penciolelli B, van Endert PM, Briand JP, Choppin J, Guillet JG
Journal of virology 2002 Oct;76(20):10219-25
Journal of virology 2002 Oct;76(20):10219-25
Magnitude and frequency of cytotoxic T-lymphocyte responses: identification of immunodominant regions of human immunodeficiency virus type 1 subtype C.
Novitsky V, Cao H, Rybak N, Gilbert P, McLane MF, Gaolekwe S, Peter T, Thior I, Ndung'u T, Marlink R, Lee TH, Essex M
Journal of virology 2002 Oct;76(20):10155-68
Journal of virology 2002 Oct;76(20):10155-68
Oral immunization with a Salmonella enterica serovar typhi vaccine induces specific circulating mucosa-homing CD4(+) and CD8(+) T cells in humans.
Lundin BS, Johansson C, Svennerholm AM
Infection and immunity 2002 Oct;70(10):5622-7
Infection and immunity 2002 Oct;70(10):5622-7
Response of in vivo protein synthesis in T lymphocytes and leucocytes to an endotoxin challenge in healthy volunteers.
Januszkiewicz A, Loré K, Essén P, Andersson B, McNurlan MA, Garlick PJ, Ringdén O, Andersson J, Wernerman J
Clinical and experimental immunology 2002 Nov;130(2):263-70
Clinical and experimental immunology 2002 Nov;130(2):263-70
Allergen-specific CD8(+) T cells and atopic disease.
Seneviratne SL, Jones L, King AS, Black A, Powell S, McMichael AJ, Ogg GS
The Journal of clinical investigation 2002 Nov;110(9):1283-91
The Journal of clinical investigation 2002 Nov;110(9):1283-91
Comprehensive screening for human immunodeficiency virus type 1 subtype-specific CD8 cytotoxic T lymphocytes and definition of degenerate epitopes restricted by HLA-A0207 and -C(W)0304 alleles.
Currier JR, deSouza M, Chanbancherd P, Bernstein W, Birx DL, Cox JH
Journal of virology 2002 May;76(10):4971-86
Journal of virology 2002 May;76(10):4971-86
Identification and characterization of the ESAT-6 homologue of Mycobacterium leprae and T-cell cross-reactivity with Mycobacterium tuberculosis.
Geluk A, van Meijgaarden KE, Franken KL, Subronto YW, Wieles B, Arend SM, Sampaio EP, de Boer T, Faber WR, Naafs B, Ottenhoff TH
Infection and immunity 2002 May;70(5):2544-8
Infection and immunity 2002 May;70(5):2544-8
Rapid induction of tumor-specific type 1 T helper cells in metastatic melanoma patients by vaccination with mature, cryopreserved, peptide-loaded monocyte-derived dendritic cells.
Schuler-Thurner B, Schultz ES, Berger TG, Weinlich G, Ebner S, Woerl P, Bender A, Feuerstein B, Fritsch PO, Romani N, Schuler G
The Journal of experimental medicine 2002 May 20;195(10):1279-88
The Journal of experimental medicine 2002 May 20;195(10):1279-88
Depletion of human NK and CD8 cells prior to in vitro H1N1 flu vaccine stimulation increases the number of gamma interferon-secreting cells compared to the initial undepleted population in an ELISPOT assay.
Dercamp C, Sanchez V, Barrier J, Trannoy E, Guy B
Clinical and diagnostic laboratory immunology 2002 Mar;9(2):230-5
Clinical and diagnostic laboratory immunology 2002 Mar;9(2):230-5
Identification of Kaposi's sarcoma-associated herpesvirus (KSHV)-specific cytotoxic T-lymphocyte epitopes and evaluation of reconstitution of KSHV-specific responses in human immunodeficiency virus type 1-Infected patients receiving highly active antiretroviral therapy.
Wilkinson J, Cope A, Gill J, Bourboulia D, Hayes P, Imami N, Kubo T, Marcelin A, Calvez V, Weiss R, Gazzard B, Boshoff C, Gotch F
Journal of virology 2002 Mar;76(6):2634-40
Journal of virology 2002 Mar;76(6):2634-40
Magnitude of functional CD8+ T-cell responses to the gag protein of human immunodeficiency virus type 1 correlates inversely with viral load in plasma.
Edwards BH, Bansal A, Sabbaj S, Bakari J, Mulligan MJ, Goepfert PA
Journal of virology 2002 Mar;76(5):2298-305
Journal of virology 2002 Mar;76(5):2298-305
Naturally exposed populations differ in their T1 and T2 responses to the circumsporozoite protein of Plasmodium falciparum.
Reece WH, Plebanski M, Akinwunmi P, Gothard P, Flanagan KL, Lee EA, Cortina-Borja M, Hill AV, Pinder M
Infection and immunity 2002 Mar;70(3):1468-74
Infection and immunity 2002 Mar;70(3):1468-74
Induction of T helper type 1 and 2 responses to 19-kilodalton merozoite surface protein 1 in vaccinated healthy volunteers and adults naturally exposed to malaria.
Lee EA, Palmer DR, Flanagan KL, Reece WH, Odhiambo K, Marsh K, Pinder M, Gravenor MB, Keitel WA, Kester KE, Diggs C, Kaslow D, Apostolopoulos V, Ballou WR, Hill AV, Krzych U, Plebanski M
Infection and immunity 2002 Mar;70(3):1417-21
Infection and immunity 2002 Mar;70(3):1417-21
T cell responses to vaccines in infants: defective IFNgamma production after oral polio vaccination.
Vekemans J, Ota MO, Wang EC, Kidd M, Borysiewicz LK, Whittle H, McAdam KP, Morgan G, Marchant A
Clinical and experimental immunology 2002 Mar;127(3):495-8
Clinical and experimental immunology 2002 Mar;127(3):495-8
Expansion of pre-existing, lymph node-localized CD8+ T cells during supervised treatment interruptions in chronic HIV-1 infection.
Altfeld M, van Lunzen J, Frahm N, Yu XG, Schneider C, Eldridge RL, Feeney ME, Meyer-Olson D, Stellbrink HJ, Walker BD
The Journal of clinical investigation 2002 Mar;109(6):837-43
The Journal of clinical investigation 2002 Mar;109(6):837-43
Detection of CD4(+)- and CD8(+)-T-cell responses to human papillomavirus type 1 antigens expressed at various stages of the virus life cycle by using an enzyme-linked immunospot assay of gamma interferon release.
Steele JC, Roberts S, Rookes SM, Gallimore PH
Journal of virology 2002 Jun;76(12):6027-36
Journal of virology 2002 Jun;76(12):6027-36
Human tumor-derived genomic DNA transduced into a recipient cell induces tumor-specific immune responses ex vivo.
Whiteside TL, Gambotto A, Albers A, Stanson J, Cohen EP
Proceedings of the National Academy of Sciences of the United States of America 2002 Jul 9;99(14):9415-20
Proceedings of the National Academy of Sciences of the United States of America 2002 Jul 9;99(14):9415-20
The magnitude and specificity of influenza A virus-specific cytotoxic T-lymphocyte responses in humans is related to HLA-A and -B phenotype.
Boon AC, de Mutsert G, Graus YM, Fouchier RA, Sintnicolaas K, Osterhaus AD, Rimmelzwaan GF
Journal of virology 2002 Jan;76(2):582-90
Journal of virology 2002 Jan;76(2):582-90
Vaccine-induced immune responses in rodents and nonhuman primates by use of a humanized human immunodeficiency virus type 1 pol gene.
Casimiro DR, Tang A, Perry HC, Long RS, Chen M, Heidecker GJ, Davies ME, Freed DC, Persaud NV, Dubey S, Smith JG, Havlir D, Richman D, Chastain MA, Simon AJ, Fu TM, Emini EA, Shiver JW
Journal of virology 2002 Jan;76(1):185-94
Journal of virology 2002 Jan;76(1):185-94
Induction of a T helper cell response against the tumor-associated antigen HER2 using monocyte-derived dendritic cells.
Metzger J, Nicklisch N, Kufer P, Peschel C, Luppa PB, Bernhard H
Cytotechnology 2002 Jan;38(1-3):155-64
Cytotechnology 2002 Jan;38(1-3):155-64
Immune responses to the Mycobacterium tuberculosis-specific antigen ESAT-6 signal subclinical infection among contacts of tuberculosis patients.
Doherty TM, Demissie A, Olobo J, Wolday D, Britton S, Eguale T, Ravn P, Andersen P
Journal of clinical microbiology 2002 Feb;40(2):704-6
Journal of clinical microbiology 2002 Feb;40(2):704-6
Frequencies of ex vivo-activated human immunodeficiency virus type 1-specific gamma-interferon-producing CD8+ T cells in infected children correlate positively with plasma viral load.
Buseyne F, Scott-Algara D, Porrot F, Corre B, Bellal N, Burgard M, Rouzioux C, Blanche S, Rivière Y
Journal of virology 2002 Dec;76(24):12414-22
Journal of virology 2002 Dec;76(24):12414-22
HLA-E-dependent presentation of Mtb-derived antigen to human CD8+ T cells.
Heinzel AS, Grotzke JE, Lines RA, Lewinsohn DA, McNabb AL, Streblow DN, Braud VM, Grieser HJ, Belisle JT, Lewinsohn DM
The Journal of experimental medicine 2002 Dec 2;196(11):1473-81
The Journal of experimental medicine 2002 Dec 2;196(11):1473-81
Human immunodeficiency virus-specific CD8(+) T cells in human breast milk.
Sabbaj S, Edwards BH, Ghosh MK, Semrau K, Cheelo S, Thea DM, Kuhn L, Ritter GD, Mulligan MJ, Goepfert PA, Aldrovandi GM
Journal of virology 2002 Aug;76(15):7365-73
Journal of virology 2002 Aug;76(15):7365-73
Inflammatory cytokines in small intestinal mucosa of patients with potential coeliac disease.
Westerholm-Ormio M, Garioch J, Ketola I, Savilahti E
Clinical and experimental immunology 2002 Apr;128(1):94-101
Clinical and experimental immunology 2002 Apr;128(1):94-101
Neonatal dendritic cells are intrinsically biased against Th-1 immune responses.
Langrish CL, Buddle JC, Thrasher AJ, Goldblatt D
Clinical and experimental immunology 2002 Apr;128(1):118-23
Clinical and experimental immunology 2002 Apr;128(1):118-23
Quantitative analysis of adenovirus-specific CD4+ T-cell responses from healthy adults.
Olive M, Eisenlohr LC, Flomenberg P
Viral immunology 2001;14(4):403-13
Viral immunology 2001;14(4):403-13
Differential immunogenicity of Epstein-Barr virus latent-cycle proteins for human CD4(+) T-helper 1 responses.
Leen A, Meij P, Redchenko I, Middeldorp J, Bloemena E, Rickinson A, Blake N
Journal of virology 2001 Sep;75(18):8649-59
Journal of virology 2001 Sep;75(18):8649-59
Association of interleukin-10 cytokine expression status with HLA non-DRB1*02 and Mycobacterium bovis BCG scar-negative status in south Indian pulmonary tuberculosis patients.
Dheenadhayalan V, Shanmugalakshmi S, Vani S, Muthuveeralakshmi P, Arivarignan G, Nageswari AD, Pitchappan RM
Infection and immunity 2001 Sep;69(9):5635-42
Infection and immunity 2001 Sep;69(9):5635-42
Structural features of peptide analogs of human histocompatibility leukocyte antigen class I epitopes that are more potent and immunogenic than wild-type peptide.
Tangri S, Ishioka GY, Huang X, Sidney J, Southwood S, Fikes J, Sette A
The Journal of experimental medicine 2001 Sep 17;194(6):833-46
The Journal of experimental medicine 2001 Sep 17;194(6):833-46
Induction of CD4(+) T cell-dependent CD8(+) type 1 responses in humans by a malaria DNA vaccine.
Wang R, Epstein J, Baraceros FM, Gorak EJ, Charoenvit Y, Carucci DJ, Hedstrom RC, Rahardjo N, Gay T, Hobart P, Stout R, Jones TR, Richie TL, Parker SE, Doolan DL, Norman J, Hoffman SL
Proceedings of the National Academy of Sciences of the United States of America 2001 Sep 11;98(19):10817-22
Proceedings of the National Academy of Sciences of the United States of America 2001 Sep 11;98(19):10817-22
Identification of human immunodeficiency virus type 1 subtype C Gag-, Tat-, Rev-, and Nef-specific elispot-based cytotoxic T-lymphocyte responses for AIDS vaccine design.
Novitsky V, Rybak N, McLane MF, Gilbert P, Chigwedere P, Klein I, Gaolekwe S, Chang SY, Peter T, Thior I, Ndung'u T, Vannberg F, Foley BT, Marlink R, Lee TH, Essex M
Journal of virology 2001 Oct;75(19):9210-28
Journal of virology 2001 Oct;75(19):9210-28
Unique T cell effector functions elicited by Plasmodium falciparum epitopes in malaria-exposed Africans tested by three T cell assays.
Flanagan KL, Lee EA, Gravenor MB, Reece WH, Urban BC, Doherty T, Bojang KA, Pinder M, Hill AV, Plebanski M
Journal of immunology (Baltimore, Md. : 1950) 2001 Oct 15;167(8):4729-37
Journal of immunology (Baltimore, Md. : 1950) 2001 Oct 15;167(8):4729-37
Characterization of HLA-A3-restricted cytotoxic T lymphocytes reactive against the widely expressed tumor antigen telomerase.
Vonderheide RH, Anderson KS, Hahn WC, Butler MO, Schultze JL, Nadler LM
Clinical cancer research : an official journal of the American Association for Cancer Research 2001 Nov;7(11):3343-8
Clinical cancer research : an official journal of the American Association for Cancer Research 2001 Nov;7(11):3343-8
Identification of cyclin B1 as a shared human epithelial tumor-associated antigen recognized by T cells.
Kao H, Marto JA, Hoffmann TK, Shabanowitz J, Finkelstein SD, Whiteside TL, Hunt DF, Finn OJ
The Journal of experimental medicine 2001 Nov 5;194(9):1313-23
The Journal of experimental medicine 2001 Nov 5;194(9):1313-23
Direct ex vivo analysis of antigen-specific IFN-gamma-secreting CD4 T cells in Mycobacterium tuberculosis-infected individuals: associations with clinical disease state and effect of treatment.
Pathan AA, Wilkinson KA, Klenerman P, McShane H, Davidson RN, Pasvol G, Hill AV, Lalvani A
Journal of immunology (Baltimore, Md. : 1950) 2001 Nov 1;167(9):5217-25
Journal of immunology (Baltimore, Md. : 1950) 2001 Nov 1;167(9):5217-25
Contribution of CD8(+) T cells to gamma interferon production in human tuberculosis.
Shams H, Wizel B, Weis SE, Samten B, Barnes PF
Infection and immunity 2001 May;69(5):3497-501
Infection and immunity 2001 May;69(5):3497-501
Induction and abrogation of LACK reactive cells in the evolution of human leishmaniasis.
Maasho K, Wolday D, Edjigu M, Söderström K, Britton S, Akuffo H
Clinical and experimental immunology 2001 May;124(2):255-61
Clinical and experimental immunology 2001 May;124(2):255-61
CD8(+) lymphocytes respond to different HIV epitopes in seronegative and infected subjects.
Kaul R, Dong T, Plummer FA, Kimani J, Rostron T, Kiama P, Njagi E, Irungu E, Farah B, Oyugi J, Chakraborty R, MacDonald KS, Bwayo JJ, McMichael A, Rowland-Jones SL
The Journal of clinical investigation 2001 May;107(10):1303-10
The Journal of clinical investigation 2001 May;107(10):1303-10
Mature dendritic cells infected with canarypox virus elicit strong anti-human immunodeficiency virus CD8+ and CD4+ T-cell responses from chronically infected individuals.
Engelmayer J, Larsson M, Lee A, Lee M, Cox WI, Steinman RM, Bhardwaj N
Journal of virology 2001 Mar;75(5):2142-53
Journal of virology 2001 Mar;75(5):2142-53
Thiols decrease cytokine levels and down-regulate the expression of CD30 on human allergen-specific T helper (Th) 0 and Th2 cells.
Bengtsson A, Lundberg M, Avila-Cariño J, Jacobsson G, Holmgren A, Scheynius A
Clinical and experimental immunology 2001 Mar;123(3):350-60
Clinical and experimental immunology 2001 Mar;123(3):350-60
Sustained dysfunction of antiviral CD8+ T lymphocytes after infection with hepatitis C virus.
Gruener NH, Lechner F, Jung MC, Diepolder H, Gerlach T, Lauer G, Walker B, Sullivan J, Phillips R, Pape GR, Klenerman P
Journal of virology 2001 Jun;75(12):5550-8
Journal of virology 2001 Jun;75(12):5550-8
Relative dominance of epitope-specific cytotoxic T-lymphocyte responses in human immunodeficiency virus type 1-infected persons with shared HLA alleles.
Day CL, Shea AK, Altfeld MA, Olson DP, Buchbinder SP, Hecht FM, Rosenberg ES, Walker BD, Kalams SA
Journal of virology 2001 Jul;75(14):6279-91
Journal of virology 2001 Jul;75(14):6279-91
Induction of neutralizing antibodies and gag-specific cellular immune responses to an R5 primary isolate of human immunodeficiency virus type 1 in rhesus macaques.
Montefiori DC, Safrit JT, Lydy SL, Barry AP, Bilska M, Vo HT, Klein M, Tartaglia J, Robinson HL, Rovinski B
Journal of virology 2001 Jul;75(13):5879-90
Journal of virology 2001 Jul;75(13):5879-90
Direct ex vivo measurement of CD8(+) T-lymphocyte responses to human parvovirus B19.
Tolfvenstam T, Oxenius A, Price DA, Shacklett BL, Spiegel HM, Hedman K, Norbeck O, Levi M, Olsen K, Kantzanou M, Nixon DF, Broliden K, Klenerman P
Journal of virology 2001 Jan;75(1):540-3
Journal of virology 2001 Jan;75(1):540-3
Failure to detect HLA-A*6802-restricted CD8+ T cells specific for Chlamydia trachomatis antigens in subjects from trachoma-endemic communities.
Mahdi OS, Whittle HC, Joof H, Mabey DC, Bailey RL
Clinical and experimental immunology 2001 Jan;123(1):68-72
Clinical and experimental immunology 2001 Jan;123(1):68-72
EBNA1-specific CD4+ T cells in healthy carriers of Epstein-Barr virus are primarily Th1 in function.
Bickham K, Münz C, Tsang ML, Larsson M, Fonteneau JF, Bhardwaj N, Steinman R
The Journal of clinical investigation 2001 Jan;107(1):121-30
The Journal of clinical investigation 2001 Jan;107(1):121-30
Antigen-specific inhibition of effector T cell function in humans after injection of immature dendritic cells.
Dhodapkar MV, Steinman RM, Krasovsky J, Munz C, Bhardwaj N
The Journal of experimental medicine 2001 Jan 15;193(2):233-8
The Journal of experimental medicine 2001 Jan 15;193(2):233-8
Substantial differences in specificity of HIV-specific cytotoxic T cells in acute and chronic HIV infection.
Goulder PJ, Altfeld MA, Rosenberg ES, Nguyen T, Tang Y, Eldridge RL, Addo MM, He S, Mukherjee JS, Phillips MN, Bunce M, Kalams SA, Sekaly RP, Walker BD, Brander C
The Journal of experimental medicine 2001 Jan 15;193(2):181-94
The Journal of experimental medicine 2001 Jan 15;193(2):181-94
Cellular immune responses and viral diversity in individuals treated during acute and early HIV-1 infection.
Altfeld M, Rosenberg ES, Shankarappa R, Mukherjee JS, Hecht FM, Eldridge RL, Addo MM, Poon SH, Phillips MN, Robbins GK, Sax PE, Boswell S, Kahn JO, Brander C, Goulder PJ, Levy JA, Mullins JI, Walker BD
The Journal of experimental medicine 2001 Jan 15;193(2):169-80
The Journal of experimental medicine 2001 Jan 15;193(2):169-80
Rapid definition of five novel HLA-A*3002-restricted human immunodeficiency virus-specific cytotoxic T-lymphocyte epitopes by elispot and intracellular cytokine staining assays.
Goulder PJ, Addo MM, Altfeld MA, Rosenberg ES, Tang Y, Govender U, Mngqundaniso N, Annamalai K, Vogel TU, Hammond M, Bunce M, Coovadia HM, Walker BD
Journal of virology 2001 Feb;75(3):1339-47
Journal of virology 2001 Feb;75(3):1339-47
Identification of novel HLA-A2-restricted human immunodeficiency virus type 1-specific cytotoxic T-lymphocyte epitopes predicted by the HLA-A2 supertype peptide-binding motif.
Altfeld MA, Livingston B, Reshamwala N, Nguyen PT, Addo MM, Shea A, Newman M, Fikes J, Sidney J, Wentworth P, Chesnut R, Eldridge RL, Rosenberg ES, Robbins GK, Brander C, Sax PE, Boswell S, Flynn T, Buchbinder S, Goulder PJ, Walker BD, Sette A, Kalams SA
Journal of virology 2001 Feb;75(3):1301-11
Journal of virology 2001 Feb;75(3):1301-11
Increased peripheral T cell reactivity to microbial antigens and collagen type II in rheumatoid arthritis after treatment with soluble TNFalpha receptors.
Berg L, Lampa J, Rogberg S, van Vollenhoven R, Klareskog L
Annals of the rheumatic diseases 2001 Feb;60(2):133-9
Annals of the rheumatic diseases 2001 Feb;60(2):133-9
Effect of deworming on human T cell responses to mycobacterial antigens in helminth-exposed individuals before and after bacille Calmette-Guérin (BCG) vaccination.
Elias D, Wolday D, Akuffo H, Petros B, Bronner U, Britton S
Clinical and experimental immunology 2001 Feb;123(2):219-25
Clinical and experimental immunology 2001 Feb;123(2):219-25
Role for HLA class II molecules in HIV-1 suppression and cellular immunity following antiretroviral treatment.
Malhotra U, Holte S, Dutta S, Berrey MM, Delpit E, Koelle DM, Sette A, Corey L, McElrath MJ
The Journal of clinical investigation 2001 Feb;107(4):505-17
The Journal of clinical investigation 2001 Feb;107(4):505-17
Immunization with a HER-2/neu helper peptide vaccine generates HER-2/neu CD8 T-cell immunity in cancer patients.
Knutson KL, Schiffman K, Disis ML
The Journal of clinical investigation 2001 Feb;107(4):477-84
The Journal of clinical investigation 2001 Feb;107(4):477-84
Late seroconversion in HIV-resistant Nairobi prostitutes despite pre-existing HIV-specific CD8+ responses.
Kaul R, Rowland-Jones SL, Kimani J, Dong T, Yang HB, Kiama P, Rostron T, Njagi E, Bwayo JJ, MacDonald KS, McMichael AJ, Plummer FA
The Journal of clinical investigation 2001 Feb;107(3):341-9
The Journal of clinical investigation 2001 Feb;107(3):341-9
Influence of atopic heredity on IL-4-, IL-12- and IFN-gamma-producing cells in in vitro activated cord blood mononuclear cells.
Gabrielsson S, Söderlund A, Nilsson C, Lilja G, Nordlund M, Troye-Blomberg M
Clinical and experimental immunology 2001 Dec;126(3):390-6
Clinical and experimental immunology 2001 Dec;126(3):390-6
Treatment of multiple sclerosis with Copaxone (COP): Elispot assay detects COP-induced interleukin-4 and interferon-gamma response in blood cells.
Farina C, Then Bergh F, Albrecht H, Meinl E, Yassouridis A, Neuhaus O, Hohlfeld R
Brain : a journal of neurology 2001 Apr;124(Pt 4):705-19
Brain : a journal of neurology 2001 Apr;124(Pt 4):705-19
Differential induction of cellular responses by live and dead Leishmania promastigotes in healthy donors.
Nylén S, Mörtberg U, Kovalenko D, Satti I, Engström K, Bakhiet M, Akuffo H
Clinical and experimental immunology 2001 Apr;124(1):43-53
Clinical and experimental immunology 2001 Apr;124(1):43-53
Specificity of T cells in synovial fluid: high frequencies of CD8(+) T cells that are specific for certain viral epitopes.
Tan LC, Mowat AG, Fazou C, Rostron T, Roskell H, Dunbar PR, Tournay C, Romagné F, Peyrat MA, Houssaint E, Bonneville M, Rickinson AB, McMichael AJ, Callan MF
Arthritis research 2000;2(2):154-64
Arthritis research 2000;2(2):154-64
Interferon-gamma production in response to in vitro stimulation with collagen type II in rheumatoid arthritis is associated with HLA-DRB1(*)0401 and HLA-DQ8.
Berg L, Rönnelid J, Sanjeevi CB, Lampa J, Klareskog L
Arthritis research 2000;2(1):75-84
Arthritis research 2000;2(1):75-84
Identification of dominant optimal HLA-B60- and HLA-B61-restricted cytotoxic T-lymphocyte (CTL) epitopes: rapid characterization of CTL responses by enzyme-linked immunospot assay.
Altfeld MA, Trocha A, Eldridge RL, Rosenberg ES, Phillips MN, Addo MM, Sekaly RP, Kalams SA, Burchett SA, McIntosh K, Walker BD, Goulder PJ
Journal of virology 2000 Sep;74(18):8541-9
Journal of virology 2000 Sep;74(18):8541-9
Cytokine production, serum levels and disease activity in systemic lupus erythematosus.
Gröndal G, Gunnarsson I, Rönnelid J, Rogberg S, Klareskog L, Lundberg I
Clinical and experimental rheumatology 2000 Sep-Oct;18(5):565-70
Clinical and experimental rheumatology 2000 Sep-Oct;18(5):565-70
Strategy for monitoring T cell responses to NY-ESO-1 in patients with any HLA class I allele.
Gnjatic S, Nagata Y, Jager E, Stockert E, Shankara S, Roberts BL, Mazzara GP, Lee SY, Dunbar PR, Dupont B, Cerundolo V, Ritter G, Chen YT, Knuth A, Old LJ
Proceedings of the National Academy of Sciences of the United States of America 2000 Sep 26;97(20):10917-22
Proceedings of the National Academy of Sciences of the United States of America 2000 Sep 26;97(20):10917-22
A significant number of human immunodeficiency virus epitope-specific cytotoxic T lymphocytes detected by tetramer binding do not produce gamma interferon.
Goepfert PA, Bansal A, Edwards BH, Ritter GD Jr, Tellez I, McPherson SA, Sabbaj S, Mulligan MJ
Journal of virology 2000 Nov;74(21):10249-55
Journal of virology 2000 Nov;74(21):10249-55
HLA class I-restricted cytotoxic T-cell epitopes of the respiratory syncytial virus fusion protein.
Brandenburg AH, de Waal L, Timmerman HH, Hoogerhout P, de Swart RL, Osterhaus AD
Journal of virology 2000 Nov;74(21):10240-4
Journal of virology 2000 Nov;74(21):10240-4
Anti-human immunodeficiency virus type 1 (HIV-1) CD8(+) T-lymphocyte reactivity during combination antiretroviral therapy in HIV-1-infected patients with advanced immunodeficiency.
Rinaldo CR Jr, Huang XL, Fan Z, Margolick JB, Borowski L, Hoji A, Kalinyak C, McMahon DK, Riddler SA, Hildebrand WH, Day RB, Mellors JW
Journal of virology 2000 May;74(9):4127-38
Journal of virology 2000 May;74(9):4127-38
Human CD4(+) T lymphocytes consistently respond to the latent Epstein-Barr virus nuclear antigen EBNA1.
Münz C, Bickham KL, Subklewe M, Tsang ML, Chahroudi A, Kurilla MG, Zhang D, O'Donnell M, Steinman RM
The Journal of experimental medicine 2000 May 15;191(10):1649-60
The Journal of experimental medicine 2000 May 15;191(10):1649-60
CD8(+) T-cell gamma interferon production specific for human immunodeficiency virus type 1 (HIV-1) in HIV-1-infected subjects.
Huang XL, Fan Z, Kalinyak C, Mellors JW, Rinaldo CR Jr
Clinical and diagnostic laboratory immunology 2000 Mar;7(2):279-87
Clinical and diagnostic laboratory immunology 2000 Mar;7(2):279-87
Differential narrow focusing of immunodominant human immunodeficiency virus gag-specific cytotoxic T-lymphocyte responses in infected African and caucasoid adults and children.
Goulder PJ, Brander C, Annamalai K, Mngqundaniso N, Govender U, Tang Y, He S, Hartman KE, O'Callaghan CA, Ogg GS, Altfeld MA, Rosenberg ES, Cao H, Kalams SA, Hammond M, Bunce M, Pelton SI, Burchett SA, McIntosh K, Coovadia HM, Walker BD
Journal of virology 2000 Jun;74(12):5679-90
Journal of virology 2000 Jun;74(12):5679-90
HLA-B57-restricted cytotoxic T-lymphocyte activity in a single infected subject toward two optimal epitopes, one of which is entirely contained within the other.
Goulder PJ, Tang Y, Pelton SI, Walker BD
Journal of virology 2000 Jun;74(11):5291-9
Journal of virology 2000 Jun;74(11):5291-9
Enhanced binding of antibodies to neutralization epitopes following thermal and chemical inactivation of human immunodeficiency virus type 1.
Grovit-Ferbas K, Hsu JF, Ferbas J, Gudeman V, Chen IS
Journal of virology 2000 Jul;74(13):5802-9
Journal of virology 2000 Jul;74(13):5802-9
Diversion of intestinal flow decreases the numbers of interleukin 4 secreting and interferon gamma secreting T lymphocytes in small bowel mucosa.
Schmit A, Van Gossum A, Carol M, Houben JJ, Mascart F
Gut 2000 Jan;46(1):40-5
Gut 2000 Jan;46(1):40-5
Consequences of cell death: exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells.
Sauter B, Albert ML, Francisco L, Larsson M, Somersan S, Bhardwaj N
The Journal of experimental medicine 2000 Feb 7;191(3):423-34
The Journal of experimental medicine 2000 Feb 7;191(3):423-34
Cross-priming of naive CD8 T cells against melanoma antigens using dendritic cells loaded with killed allogeneic melanoma cells.
Berard F, Blanco P, Davoust J, Neidhart-Berard EM, Nouri-Shirazi M, Taquet N, Rimoldi D, Cerottini JC, Banchereau J, Palucka AK
The Journal of experimental medicine 2000 Dec 4;192(11):1535-44
The Journal of experimental medicine 2000 Dec 4;192(11):1535-44
Functionally inert HIV-specific cytotoxic T lymphocytes do not play a major role in chronically infected adults and children.
Goulder PJ, Tang Y, Brander C, Betts MR, Altfeld M, Annamalai K, Trocha A, He S, Rosenberg ES, Ogg G, O'Callaghan CA, Kalams SA, McKinney RE Jr, Mayer K, Koup RA, Pelton SI, Burchett SK, McIntosh K, Walker BD
The Journal of experimental medicine 2000 Dec 18;192(12):1819-32
The Journal of experimental medicine 2000 Dec 18;192(12):1819-32
Characterization of a novel respiratory syncytial virus-specific human cytotoxic T-lymphocyte epitope.
Goulder PJ, Lechner F, Klenerman P, McIntosh K, Walker BD
Journal of virology 2000 Aug;74(16):7694-7
Journal of virology 2000 Aug;74(16):7694-7
Down-regulation of the T cell receptor CD3 zeta chain in rheumatoid arthritis (RA) and its influence on T cell responsiveness.
Berg L, Rönnelid J, Klareskog L, Bucht A
Clinical and experimental immunology 2000 Apr;120(1):174-82
Clinical and experimental immunology 2000 Apr;120(1):174-82
Multiple sclerosis is associated with an imbalance between tumour necrosis factor-alpha (TNF-alpha)- and IL-10-secreting blood cells that is corrected by interferon-beta (IFN-beta) treatment.
Ozenci V, Kouwenhoven M, Huang YM, Kivisäkk P, Link H
Clinical and experimental immunology 2000 Apr;120(1):147-53
Clinical and experimental immunology 2000 Apr;120(1):147-53
Monitoring CD8 T cell responses to NY-ESO-1: correlation of humoral and cellular immune responses.
Jäger E, Nagata Y, Gnjatic S, Wada H, Stockert E, Karbach J, Dunbar PR, Lee SY, Jungbluth A, Jäger D, Arand M, Ritter G, Cerundolo V, Dupont B, Chen YT, Old LJ, Knuth A
Proceedings of the National Academy of Sciences of the United States of America 2000 Apr 25;97(9):4760-5
Proceedings of the National Academy of Sciences of the United States of America 2000 Apr 25;97(9):4760-5
Genetic control of schistosome infections by the SM1 locus of the 5q31-q33 region is linked to differentiation of type 2 helper T lymphocytes.
Rodrigues V Jr, Piper K, Couissinier-Paris P, Bacelar O, Dessein H, Dessein AJ
Infection and immunity 1999 Sep;67(9):4689-92
Infection and immunity 1999 Sep;67(9):4689-92
Is an epitope on keratin 17 a major target for autoreactive T lymphocytes in psoriasis?
Gudmundsdottir AS, Sigmundsdottir H, Sigurgeirsson B, Good MF, Valdimarsson H, Jonsdottir I
Clinical and experimental immunology 1999 Sep;117(3):580-6
Clinical and experimental immunology 1999 Sep;117(3):580-6
Natural killer cells in cross-regulation of IL-12 by IL-10 in Leishmania antigen-stimulated blood donor cells.
Akuffo H, Alexis A, Eidsmo L, Saed A, Nylén S, Maasho K
Clinical and experimental immunology 1999 Sep;117(3):529-34
Clinical and experimental immunology 1999 Sep;117(3):529-34
High frequencies of naive Melan-A/MART-1-specific CD8(+) T cells in a large proportion of human histocompatibility leukocyte antigen (HLA)-A2 individuals.
Pittet MJ, Valmori D, Dunbar PR, Speiser DE, Liénard D, Lejeune F, Fleischhauer K, Cerundolo V, Cerottini JC, Romero P
The Journal of experimental medicine 1999 Sep 6;190(5):705-15
The Journal of experimental medicine 1999 Sep 6;190(5):705-15
Induction of HIV-1-specific T cell responses by administration of cytokines in late-stage patients receiving highly active anti-retroviral therapy.
Imami N, Hardy GA, Nelson MR, Morris-Jones S, Al-Shahi R, Antonopoulos C, Gazzard B, Gotch FM
Clinical and experimental immunology 1999 Oct;118(1):78-86
Clinical and experimental immunology 1999 Oct;118(1):78-86
Identification of naturally processed and HLA-presented Epstein-Barr virus peptides recognized by CD4(+) or CD8(+) T lymphocytes from human blood.
Herr W, Ranieri E, Gambotto A, Kierstead LS, Amoscato AA, Gesualdo L, Storkus WJ
Proceedings of the National Academy of Sciences of the United States of America 1999 Oct 12;96(21):12033-8
Proceedings of the National Academy of Sciences of the United States of America 1999 Oct 12;96(21):12033-8
T-cell recognition of Mycobacterium tuberculosis culture filtrate fractions in tuberculosis patients and their household contacts.
Demissie A, Ravn P, Olobo J, Doherty TM, Eguale T, Geletu M, Hailu W, Andersen P, Britton S
Infection and immunity 1999 Nov;67(11):5967-71
Infection and immunity 1999 Nov;67(11):5967-71
Control of Leishmania infantum infection is associated with CD8(+) and gamma interferon- and interleukin-5-producing CD4(+) antigen-specific T cells.
Mary C, Auriault V, Faugère B, Dessein AJ
Infection and immunity 1999 Nov;67(11):5559-66
Infection and immunity 1999 Nov;67(11):5559-66
Differential T-cell recognition of native and recombinant Mycobacterium tuberculosis GroES.
Rosenkrands I, Weldingh K, Ravn P, Brandt L, Højrup P, Rasmussen PB, Coates AR, Singh M, Mascagni P, Andersen P
Infection and immunity 1999 Nov;67(11):5552-8
Infection and immunity 1999 Nov;67(11):5552-8
Increased levels of circulating acetylcholine receptor (AChR)-reactive IL-10-secreting cells are characteristic for myasthenia gravis (MG).
Huang YM, Kivisäkk P, Ozenci V, Pirskanen R, Link H
Clinical and experimental immunology 1999 Nov;118(2):304-8
Clinical and experimental immunology 1999 Nov;118(2):304-8
Weak anti-HIV CD8(+) T-cell effector activity in HIV primary infection.
Dalod M, Dupuis M, Deschemin JC, Goujard C, Deveau C, Meyer L, Ngo N, Rouzioux C, Guillet JG, Delfraissy JF, Sinet M, Venet A
The Journal of clinical investigation 1999 Nov;104(10):1431-9
The Journal of clinical investigation 1999 Nov;104(10):1431-9
A new cell enzyme-linked immunosorbent assay demonstrates gamma interferon suppression by beta interferon in multiple sclerosis.
Bakhiet M, Ozenci V, Withagen C, Mustafa M, Fredrikson S, Link H
Clinical and diagnostic laboratory immunology 1999 May;6(3):415-9
Clinical and diagnostic laboratory immunology 1999 May;6(3):415-9
Lysophosphatidylcholine (LPC) induces proinflammatory cytokines by a platelet-activating factor (PAF) receptor-dependent mechanism.
Huang YH, Schäfer-Elinder L, Wu R, Claesson HE, Frostegård J
Clinical and experimental immunology 1999 May;116(2):326-31
Clinical and experimental immunology 1999 May;116(2):326-31
Cytokine-producing cells in peripheral blood of children with coeliac disease secrete cytokines with a type 1 profile.
Hansson T, Dannaeus A, Klareskog L
Clinical and experimental immunology 1999 May;116(2):246-50
Clinical and experimental immunology 1999 May;116(2):246-50
A recombinant vaccinia virus based ELISPOT assay detects high frequencies of Pol-specific CD8 T cells in HIV-1-positive individuals.
Larsson M, Jin X, Ramratnam B, Ogg GS, Engelmayer J, Demoitie MA, McMichael AJ, Cox WI, Steinman RM, Nixon D, Bhardwaj N
AIDS (London, England) 1999 May 7;13(7):767-77
AIDS (London, England) 1999 May 7;13(7):767-77
Asymptomatic Borrelia-seropositive individuals display the same incidence of Borrelia-specific interferon-gamma (IFN-gamma)-secreting cells in blood as patients with clinical Borrelia infection.
Ekerfelt C, Forsberg P, Svenvik M, Roberg M, Bergström S, Ernerudh J
Clinical and experimental immunology 1999 Mar;115(3):498-502
Clinical and experimental immunology 1999 Mar;115(3):498-502
Levels of gamma interferon and interleukin-4 are inversely related to the levels of their corresponding autoantibodies in patients with lower respiratory tract infection.
ElKarim R, Granert C, Lindquist L, Link H, Bakhiet M
Infection and immunity 1999 Jun;67(6):3051-4
Infection and immunity 1999 Jun;67(6):3051-4
Proviral load and immune function in blood and lymph node during HIV-1 and HIV-2 infection.
Jobe O, Ariyoshi K, Marchant A, Sabally S, Corrah T, Berry N, Jaffar S, Whittle H
Clinical and experimental immunology 1999 Jun;116(3):474-8
Clinical and experimental immunology 1999 Jun;116(3):474-8
Interleukin-10 responses to liver-stage antigen 1 predict human resistance to Plasmodium falciparum.
Kurtis JD, Lanar DE, Opollo M, Duffy PE
Infection and immunity 1999 Jul;67(7):3424-9
Infection and immunity 1999 Jul;67(7):3424-9
Rapid generation of broad T-cell immunity in humans after a single injection of mature dendritic cells.
Dhodapkar MV, Steinman RM, Sapp M, Desai H, Fossella C, Krasovsky J, Donahoe SM, Dunbar PR, Cerundolo V, Nixon DF, Bhardwaj N
The Journal of clinical investigation 1999 Jul;104(2):173-80
The Journal of clinical investigation 1999 Jul;104(2):173-80
Strong human immunodeficiency virus (HIV)-specific cytotoxic T-lymphocyte activity in Sydney Blood Bank Cohort patients infected with nef-defective HIV type 1.
Dyer WB, Ogg GS, Demoitie MA, Jin X, Geczy AF, Rowland-Jones SL, McMichael AJ, Nixon DF, Sullivan JS
Journal of virology 1999 Jan;73(1):436-43
Journal of virology 1999 Jan;73(1):436-43
Dendritic cells transduced with an adenovirus vector encoding Epstein-Barr virus latent membrane protein 2B: a new modality for vaccination.
Ranieri E, Herr W, Gambotto A, Olson W, Rowe D, Robbins PD, Kierstead LS, Watkins SC, Gesualdo L, Storkus WJ
Journal of virology 1999 Dec;73(12):10416-25
Journal of virology 1999 Dec;73(12):10416-25
Vaccination with mage-3A1 peptide-pulsed mature, monocyte-derived dendritic cells expands specific cytotoxic T cells and induces regression of some metastases in advanced stage IV melanoma.
Thurner B, Haendle I, Röder C, Dieckmann D, Keikavoussi P, Jonuleit H, Bender A, Maczek C, Schreiner D, von den Driesch P, Bröcker EB, Steinman RM, Enk A, Kämpgen E, Schuler G
The Journal of experimental medicine 1999 Dec 6;190(11):1669-78
The Journal of experimental medicine 1999 Dec 6;190(11):1669-78
T cell proliferation, MHC class II restriction and cytokine products of gliadin-stimulated peripheral blood mononuclear cells (PBMC).
O'Keeffe J, Mills K, Jackson J, Feighery C
Clinical and experimental immunology 1999 Aug;117(2):269-76
Clinical and experimental immunology 1999 Aug;117(2):269-76
Antigen-specific B and T cells in human/mouse radiation chimera following immunization in vivo.
Böcher WO, Marcus H, Shakarchy R, Dekel B, Shouval D, Galun E, Reisner Y
Immunology 1999 Apr;96(4):634-41
Immunology 1999 Apr;96(4):634-41
Recovery from Guillain-Barré syndrome is associated with increased levels of neutralizing autoantibodies to interferon-gamma.
Elkarim RA, Dahle C, Mustafa M, Press R, Zou LP, Ekerfelt C, Ernerudh J, Link H, Bakhiet M
Clinical immunology and immunopathology 1998 Sep;88(3):241-8
Clinical immunology and immunopathology 1998 Sep;88(3):241-8
Peptide-specific T cell response to Mycobacterium tuberculosis: clinical spectrum, compartmentalization, and effect of chemotherapy.
Wilkinson RJ, Vordermeier HM, Wilkinson KA, Sjölund A, Moreno C, Pasvol G, Ivanyi J
The Journal of infectious diseases 1998 Sep;178(3):760-8
The Journal of infectious diseases 1998 Sep;178(3):760-8
Cytotoxic T cell responses to multiple conserved HIV epitopes in HIV-resistant prostitutes in Nairobi.
Rowland-Jones SL, Dong T, Fowke KR, Kimani J, Krausa P, Newell H, Blanchard T, Ariyoshi K, Oyugi J, Ngugi E, Bwayo J, MacDonald KS, McMichael AJ, Plummer FA
The Journal of clinical investigation 1998 Nov 1;102(9):1758-65
The Journal of clinical investigation 1998 Nov 1;102(9):1758-65
Spontaneous secretion of interferon gamma and interleukin 4 by human intraepithelial and lamina propria gut lymphocytes.
Carol M, Lambrechts A, Van Gossum A, Libin M, Goldman M, Mascart-Lemone F
Gut 1998 May;42(5):643-9
Gut 1998 May;42(5):643-9
Increased numbers of circulating interferon-gamma- and interleukin-4-secreting cells during normal pregnancy.
Matthiesen L, Ekerfelt C, Berg G, Ernerudh J
American journal of reproductive immunology (New York, N.Y. : 1989) 1998 Jun;39(6):362-7
American journal of reproductive immunology (New York, N.Y. : 1989) 1998 Jun;39(6):362-7
Human cytolytic and interferon gamma-secreting CD8+ T lymphocytes specific for Mycobacterium tuberculosis.
Lalvani A, Brookes R, Wilkinson RJ, Malin AS, Pathan AA, Andersen P, Dockrell H, Pasvol G, Hill AV
Proceedings of the National Academy of Sciences of the United States of America 1998 Jan 6;95(1):270-5
Proceedings of the National Academy of Sciences of the United States of America 1998 Jan 6;95(1):270-5
38 000 MW antigen-specific major histocompatibility complex class I restricted interferon-gamma-secreting CD8+ T cells in healthy contacts of tuberculosis.
Wilkinson RJ, Zhu X, Wilkinson KA, Lalvani A, Ivanyi J, Pasvol G, Vordermeier HM
Immunology 1998 Dec;95(4):585-90
Immunology 1998 Dec;95(4):585-90
Local cytokine response in Helicobacter pylori-infected subjects.
Lindholm C, Quiding-Järbrink M, Lönroth H, Hamlet A, Svennerholm AM
Infection and immunity 1998 Dec;66(12):5964-71
Infection and immunity 1998 Dec;66(12):5964-71
Differential regulation of Th1 and Th2 cells by p91-110 and p21-40 peptides of the 16-kD alpha-crystallin antigen of Mycobacterium tuberculosis.
Agrewala JN, Wilkinson RJ
Clinical and experimental immunology 1998 Dec;114(3):392-7
Clinical and experimental immunology 1998 Dec;114(3):392-7
Linomide (roquinimex) affects the balance between pro- and anti-inflammatory cytokines in vitro in multiple sclerosis.
Tian WZ, Navikas V, Matusevicius D, Söderström M, Fredrikson S, Hedlund G, Link H
Acta neurologica Scandinavica 1998 Aug;98(2):94-101
Acta neurologica Scandinavica 1998 Aug;98(2):94-101
Rapid effector function in CD8+ memory T cells.
Lalvani A, Brookes R, Hambleton S, Britton WJ, Hill AV, McMichael AJ
The Journal of experimental medicine 1997 Sep 15;186(6):859-65
The Journal of experimental medicine 1997 Sep 15;186(6):859-65
Analysis of TH1 and TH2 cytokine production in low grade B cell gastric MALT-type lymphomas stimulated in vitro with Helicobacter pylori.
Hauer AC, Finn TM, MacDonald TT, Spencer J, Isaacson PG
Journal of clinical pathology 1997 Nov;50(11):957-9
Journal of clinical pathology 1997 Nov;50(11):957-9
Evaluation of the recombinant 38-kilodalton antigen of Mycobacterium tuberculosis as a potential immunodiagnostic reagent.
Wilkinson RJ, Hasløv K, Rappuoli R, Giovannoni F, Narayanan PR, Desai CR, Vordermeier HM, Paulsen J, Pasvol G, Ivanyi J, Singh M
Journal of clinical microbiology 1997 Mar;35(3):553-7
Journal of clinical microbiology 1997 Mar;35(3):553-7
Peripheral blood in Sjögren's syndrome does not contain increased levels of T lymphocytes reactive with the recombinant Ro/SS-A 52 kD and La/SS-B 48 kD autoantigens.
Halse AK, Wahren M, Jonsson R
Autoimmunity 1996;23(1):25-34
Autoimmunity 1996;23(1):25-34
T cell responses to a mixture of Mycobacterium tuberculosis peptides with complementary HLA-DR binding profiles.
Jurcevic S, Hills A, Pasvol G, Davidson RN, Ivanyi J, Wilkinson RJ
Clinical and experimental immunology 1996 Sep;105(3):416-21
Clinical and experimental immunology 1996 Sep;105(3):416-21
Local entrapment of interferon gamma in the recovery from Shigella dysenteriae type 1 infection.
Raqib R, Ljungdahl A, Lindberg AA, Andersson U, Andersson J
Gut 1996 Mar;38(3):328-36
Gut 1996 Mar;38(3):328-36
Effects of in vitro hyperthermia on proliferative responses and lymphocyte activity.
Huang YH, Haegerstrand A, Frostegård J
Clinical and experimental immunology 1996 Jan;103(1):61-6
Clinical and experimental immunology 1996 Jan;103(1):61-6
The outer surface proteins of Lyme disease borrelia spirochetes stimulate T cells to secrete interferon-gamma (IFN-gamma): diagnostic and pathogenic implications.
Forsberg P, Ernerudh J, Ekerfelt C, Roberg M, Vrethem M, Bergström S
Clinical and experimental immunology 1995 Sep;101(3):453-60
Clinical and experimental immunology 1995 Sep;101(3):453-60
Interferon gamma and interleukin 4 secreting cells in the gastric antrum in Helicobacter pylori positive and negative gastritis.
Karttunen R, Karttunen T, Ekre HP, MacDonald TT
Gut 1995 Mar;36(3):341-5
Gut 1995 Mar;36(3):341-5
Th1/Th2 profiles in tuberculosis, based on the proliferation and cytokine response of blood lymphocytes to mycobacterial antigens.
Surcel HM, Troye-Blomberg M, Paulie S, Andersson G, Moreno C, Pasvol G, Ivanyi J
Immunology 1994 Feb;81(2):171-6
Immunology 1994 Feb;81(2):171-6
Number of interleukin-4- and interferon-gamma-secreting human T cells reactive with tetanus toxoid and the mycobacterial antigen PPD or phytohemagglutinin: distinct response profiles depending on the type of antigen used for activation.
elGhazali GE, Paulie S, Andersson G, Hansson Y, Holmquist G, Sun JB, Olsson T, Ekre HP, Troye-Blomberg M
European journal of immunology 1993 Nov;23(11):2740-5
European journal of immunology 1993 Nov;23(11):2740-5
Reverse ELISPOT assay for clonal analysis of cytokine production. I. Enumeration of gamma-interferon-secreting cells.
Czerkinsky C, Andersson G, Ekre HP, Nilsson LA, Klareskog L, Ouchterlony O
Journal of immunological methods 1988 May 25;110(1):29-36
Journal of immunological methods 1988 May 25;110(1):29-36
Genetic heterogeneity in Duchenne muscular dystrophy.
Zatz M, Rabbi-Bortolini E
American journal of medical genetics 1987 Jan;26(1):237
American journal of medical genetics 1987 Jan;26(1):237
Malathion A and B esterases of mouse liver-I.
Bhagwat VM, Ramachandran BV
Biochemical pharmacology 1975 Sep 15;24(18):1713-7
Biochemical pharmacology 1975 Sep 15;24(18):1713-7
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