RA0312

antibody from Oursmab

Targeting: IFNG

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunocytochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

RA0312

Provider

Oursmab

Product name

Fontolizumab (Biosimilar Reference Antibody) (IFNG)

Antibody type

Monoclonal

Description

Fontolizumab was an investigational, humanized monoclonal antibody developed for the treatment of inflammatory and autoimmune diseases, particularly Crohn's disease. It functioned as a targeted interferon-gamma (IFN-¦Ã) inhibitor. By binding to and neutralizing IFN-¦Ã in the bloodstream, fontolizumab aimed to suppress the activity of this key pro-inflammatory cytokine, which is central to the Th1-mediated immune response implicated in the pathogenesis of Crohn's disease. The goal was to reduce the excessive inflammation in the intestinal tract and induce clinical remission.

Reactivity

Human

Isotype

IgG

Vial size

100 ¦Ìg,1 mg,5 mg,10 mg,25 mg,50 mg,100 mg

Concentration

Bottled at the concentration indicated on the vial.

Storage

Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.