Antibody data
- Antibody Data
- Antigen structure
- References [23]
- Comments [0]
- Validations [0]
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- Product number
- MAB285 - Provider product page
- Provider
- R&D Systems
- Product name
- Anti-Human IFN-gamma Monoclonal Antibody (Clone 25718)
- Antibody type
- Monoclonal
- Antigen
- E. coli-derived recombinant human IFN-γ, Gln24-Gln166
- Description
- Protein A or G purified from hybridoma culture supernatant
- Reactivity
- Human
- Host
- Mouse
- Antigen sequence
AAP20098.1
- Isotype
- IgG
- Vial size
- 500 µg
Submitted references DDIT4 and Associated lncDDIT4 Modulate Th17 Differentiation through the DDIT4/TSC/mTOR Pathway.
Bilirubin suppresses Th17 immunity in colitis by upregulating CD39.
PUM1 is a biphasic negative regulator of innate immunity genes by suppressing LGP2.
Modulation of Stat-1 in Human Macrophages Infected with Different Species of Intracellular Pathogenic Bacteria.
Innate Invariant NKT Cell Recognition of HIV-1-Infected Dendritic Cells Is an Early Detection Mechanism Targeted by Viral Immune Evasion.
Production of Proinflammatory Cytokines by Monocytes in Liver-Transplanted Recipients with De Novo Autoimmune Hepatitis Is Enhanced and Induces TH1-like Regulatory T Cells.
The long intergenic noncoding RNA landscape of human lymphocytes highlights the regulation of T cell differentiation by linc-MAF-4.
Vitamin D up-regulates the vitamin D receptor by protecting it from proteasomal degradation in human CD4+ T cells.
The transcription factor PU.1 is required for the development of IL-9-producing T cells and allergic inflammation.
Impaired development of human Th1 cells in patients with deficient expression of STAT4.
In vivo blockade of OX40 ligand inhibits thymic stromal lymphopoietin driven atopic inflammation.
Evidence for downregulation of erythropoietin receptor in bone marrow erythroid cells of patients with chronic idiopathic neutropenia.
Human intestinal intraepithelial lymphocytes keep TNF alpha levels low by cell uptake and feedback inhibition of transcription.
Peripheral expansion of circulating T-helper 1 cells predicts coronary endothelial dysfunction after cardiac transplantation.
IL-15 and the initiation of cell contact-dependent synovial fibroblast-T lymphocyte cross-talk in rheumatoid arthritis: effect of methotrexate.
IL-15 and the initiation of cell contact-dependent synovial fibroblast-T lymphocyte cross-talk in rheumatoid arthritis: effect of methotrexate.
Reprogramming of IL-10 activity and signaling by IFN-gamma.
Reprogramming of IL-10 activity and signaling by IFN-gamma.
In human B cells, IL-12 triggers a cascade of molecular events similar to Th1 commitment.
Cutting edge: immune cells as sources and targets of the IL-10 family members?
Cutting edge: immune cells as sources and targets of the IL-10 family members?
Decreased IL-15 may contribute to elevated IgE and acute inflammation in atopic dermatitis.
Decreased IL-15 may contribute to elevated IgE and acute inflammation in atopic dermatitis.
Zhang F, Liu G, Li D, Wei C, Hao J
Journal of immunology (Baltimore, Md. : 1950) 2018 Mar 1;200(5):1618-1626
Journal of immunology (Baltimore, Md. : 1950) 2018 Mar 1;200(5):1618-1626
Bilirubin suppresses Th17 immunity in colitis by upregulating CD39.
Longhi MS, Vuerich M, Kalbasi A, Kenison JE, Yeste A, Csizmadia E, Vaughn B, Feldbrugge L, Mitsuhashi S, Wegiel B, Otterbein L, Moss A, Quintana FJ, Robson SC
JCI insight 2017 May 4;2(9)
JCI insight 2017 May 4;2(9)
PUM1 is a biphasic negative regulator of innate immunity genes by suppressing LGP2.
Liu Y, Qu L, Liu Y, Roizman B, Zhou GG
Proceedings of the National Academy of Sciences of the United States of America 2017 Aug 15;114(33):E6902-E6911
Proceedings of the National Academy of Sciences of the United States of America 2017 Aug 15;114(33):E6902-E6911
Modulation of Stat-1 in Human Macrophages Infected with Different Species of Intracellular Pathogenic Bacteria.
Schiavano GF, Dominici S, Rinaldi L, Cangiano AM, Brandi G, Magnani M
Journal of immunology research 2016;2016:5086928
Journal of immunology research 2016;2016:5086928
Innate Invariant NKT Cell Recognition of HIV-1-Infected Dendritic Cells Is an Early Detection Mechanism Targeted by Viral Immune Evasion.
Paquin-Proulx D, Gibbs A, Bächle SM, Checa A, Introini A, Leeansyah E, Wheelock CE, Nixon DF, Broliden K, Tjernlund A, Moll M, Sandberg JK
Journal of immunology (Baltimore, Md. : 1950) 2016 Sep 1;197(5):1843-51
Journal of immunology (Baltimore, Md. : 1950) 2016 Sep 1;197(5):1843-51
Production of Proinflammatory Cytokines by Monocytes in Liver-Transplanted Recipients with De Novo Autoimmune Hepatitis Is Enhanced and Induces TH1-like Regulatory T Cells.
Arterbery AS, Osafo-Addo A, Avitzur Y, Ciarleglio M, Deng Y, Lobritto SJ, Martinez M, Hafler DA, Kleinewietfeld M, Ekong UD
Journal of immunology (Baltimore, Md. : 1950) 2016 May 15;196(10):4040-51
Journal of immunology (Baltimore, Md. : 1950) 2016 May 15;196(10):4040-51
The long intergenic noncoding RNA landscape of human lymphocytes highlights the regulation of T cell differentiation by linc-MAF-4.
Ranzani V, Rossetti G, Panzeri I, Arrigoni A, Bonnal RJ, Curti S, Gruarin P, Provasi E, Sugliano E, Marconi M, De Francesco R, Geginat J, Bodega B, Abrignani S, Pagani M
Nature immunology 2015 Mar;16(3):318-325
Nature immunology 2015 Mar;16(3):318-325
Vitamin D up-regulates the vitamin D receptor by protecting it from proteasomal degradation in human CD4+ T cells.
Kongsbak M, von Essen MR, Boding L, Levring TB, Schjerling P, Lauritsen JP, Woetmann A, Ødum N, Bonefeld CM, Geisler C
PloS one 2014;9(5):e96695
PloS one 2014;9(5):e96695
The transcription factor PU.1 is required for the development of IL-9-producing T cells and allergic inflammation.
Chang HC, Sehra S, Goswami R, Yao W, Yu Q, Stritesky GL, Jabeen R, McKinley C, Ahyi AN, Han L, Nguyen ET, Robertson MJ, Perumal NB, Tepper RS, Nutt SL, Kaplan MH
Nature immunology 2010 Jun;11(6):527-34
Nature immunology 2010 Jun;11(6):527-34
Impaired development of human Th1 cells in patients with deficient expression of STAT4.
Chang HC, Han L, Goswami R, Nguyen ET, Pelloso D, Robertson MJ, Kaplan MH
Blood 2009 Jun 4;113(23):5887-90
Blood 2009 Jun 4;113(23):5887-90
In vivo blockade of OX40 ligand inhibits thymic stromal lymphopoietin driven atopic inflammation.
Seshasayee D, Lee WP, Zhou M, Shu J, Suto E, Zhang J, Diehl L, Austin CD, Meng YG, Tan M, Bullens SL, Seeber S, Fuentes ME, Labrijn AF, Graus YM, Miller LA, Schelegle ES, Hyde DM, Wu LC, Hymowitz SG, Martin F
The Journal of clinical investigation 2007 Dec;117(12):3868-78
The Journal of clinical investigation 2007 Dec;117(12):3868-78
Evidence for downregulation of erythropoietin receptor in bone marrow erythroid cells of patients with chronic idiopathic neutropenia.
Pontikoglou C, Liapakis G, Pyrovolaki K, Papadakis M, Bux J, Eliopoulos GD, Papadaki HA
Experimental hematology 2006 Oct;34(10):1312-22
Experimental hematology 2006 Oct;34(10):1312-22
Human intestinal intraepithelial lymphocytes keep TNF alpha levels low by cell uptake and feedback inhibition of transcription.
Ebert EC, Mehta V
Cellular immunology 2006 May;241(1):7-13
Cellular immunology 2006 May;241(1):7-13
Peripheral expansion of circulating T-helper 1 cells predicts coronary endothelial dysfunction after cardiac transplantation.
Methe H, Wiegand D, Welsch U, Krombach F, Meiser B, Nabauer M, Koglin J
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2005 Jul;24(7):833-40
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2005 Jul;24(7):833-40
IL-15 and the initiation of cell contact-dependent synovial fibroblast-T lymphocyte cross-talk in rheumatoid arthritis: effect of methotrexate.
Miranda-Carús ME, Balsa A, Benito-Miguel M, Pérez de Ayala C, Martín-Mola E
Journal of immunology (Baltimore, Md. : 1950) 2004 Jul 15;173(2):1463-76
Journal of immunology (Baltimore, Md. : 1950) 2004 Jul 15;173(2):1463-76
IL-15 and the initiation of cell contact-dependent synovial fibroblast-T lymphocyte cross-talk in rheumatoid arthritis: effect of methotrexate.
Miranda-Carús ME, Balsa A, Benito-Miguel M, Pérez de Ayala C, Martín-Mola E
Journal of immunology (Baltimore, Md. : 1950) 2004 Jul 15;173(2):1463-76
Journal of immunology (Baltimore, Md. : 1950) 2004 Jul 15;173(2):1463-76
Reprogramming of IL-10 activity and signaling by IFN-gamma.
Herrero C, Hu X, Li WP, Samuels S, Sharif MN, Kotenko S, Ivashkiv LB
Journal of immunology (Baltimore, Md. : 1950) 2003 Nov 15;171(10):5034-41
Journal of immunology (Baltimore, Md. : 1950) 2003 Nov 15;171(10):5034-41
Reprogramming of IL-10 activity and signaling by IFN-gamma.
Herrero C, Hu X, Li WP, Samuels S, Sharif MN, Kotenko S, Ivashkiv LB
Journal of immunology (Baltimore, Md. : 1950) 2003 Nov 15;171(10):5034-41
Journal of immunology (Baltimore, Md. : 1950) 2003 Nov 15;171(10):5034-41
In human B cells, IL-12 triggers a cascade of molecular events similar to Th1 commitment.
Durali D, de Goër de Herve MG, Giron-Michel J, Azzarone B, Delfraissy JF, Taoufik Y
Blood 2003 Dec 1;102(12):4084-9
Blood 2003 Dec 1;102(12):4084-9
Cutting edge: immune cells as sources and targets of the IL-10 family members?
Wolk K, Kunz S, Asadullah K, Sabat R
Journal of immunology (Baltimore, Md. : 1950) 2002 Jun 1;168(11):5397-402
Journal of immunology (Baltimore, Md. : 1950) 2002 Jun 1;168(11):5397-402
Cutting edge: immune cells as sources and targets of the IL-10 family members?
Wolk K, Kunz S, Asadullah K, Sabat R
Journal of immunology (Baltimore, Md. : 1950) 2002 Jun 1;168(11):5397-402
Journal of immunology (Baltimore, Md. : 1950) 2002 Jun 1;168(11):5397-402
Decreased IL-15 may contribute to elevated IgE and acute inflammation in atopic dermatitis.
Ong PY, Hamid QA, Travers JB, Strickland I, Al Kerithy M, Boguniewicz M, Leung DY
Journal of immunology (Baltimore, Md. : 1950) 2002 Jan 1;168(1):505-10
Journal of immunology (Baltimore, Md. : 1950) 2002 Jan 1;168(1):505-10
Decreased IL-15 may contribute to elevated IgE and acute inflammation in atopic dermatitis.
Ong PY, Hamid QA, Travers JB, Strickland I, Al Kerithy M, Boguniewicz M, Leung DY
Journal of immunology (Baltimore, Md. : 1950) 2002 Jan 1;168(1):505-10
Journal of immunology (Baltimore, Md. : 1950) 2002 Jan 1;168(1):505-10
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