Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- ABIN252586 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Suppressor of Cytokine Signaling 1 (SOCS1) antibody
- Antibody type
- Polyclonal
- Description
- Unpurified
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Vial size
- 0.2 mL
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
- Handling
- Avoid freeze-thaw cycles
Submitted references SOCS-1 mediates ubiquitylation and degradation of GM-CSF receptor.
Loss of JAK2 regulation via a heterodimeric VHL-SOCS1 E3 ubiquitin ligase underlies Chuvash polycythemia.
IL-7 engages multiple mechanisms to overcome chronic viral infection and limit organ pathology.
SOCS1 regulates the IFN but not NFkappaB pathway in TLR-stimulated human monocytes and macrophages.
Bunda S, Kommaraju K, Heir P, Ohh M
PloS one 2013;8(9):e76370
PloS one 2013;8(9):e76370
Loss of JAK2 regulation via a heterodimeric VHL-SOCS1 E3 ubiquitin ligase underlies Chuvash polycythemia.
Russell RC, Sufan RI, Zhou B, Heir P, Bunda S, Sybingco SS, Greer SN, Roche O, Heathcote SA, Chow VW, Boba LM, Richmond TD, Hickey MM, Barber DL, Cheresh DA, Simon MC, Irwin MS, Kim WY, Ohh M
Nature medicine 2011 Jun 19;17(7):845-53
Nature medicine 2011 Jun 19;17(7):845-53
IL-7 engages multiple mechanisms to overcome chronic viral infection and limit organ pathology.
Pellegrini M, Calzascia T, Toe JG, Preston SP, Lin AE, Elford AR, Shahinian A, Lang PA, Lang KS, Morre M, Assouline B, Lahl K, Sparwasser T, Tedder TF, Paik JH, DePinho RA, Basta S, Ohashi PS, Mak TW
Cell 2011 Feb 18;144(4):601-13
Cell 2011 Feb 18;144(4):601-13
SOCS1 regulates the IFN but not NFkappaB pathway in TLR-stimulated human monocytes and macrophages.
PrĂȘle CM, Woodward EA, Bisley J, Keith-Magee A, Nicholson SE, Hart PH
Journal of immunology (Baltimore, Md. : 1950) 2008 Dec 1;181(11):8018-26
Journal of immunology (Baltimore, Md. : 1950) 2008 Dec 1;181(11):8018-26
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Supportive validation
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- antibodies-online (provider)
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- Experimental details
- WB