Explore
Validate
Learn
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- NB100-56637 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB100-56637, RRID:AB_838919
- Product name
- Rabbit Polyclonal SOCS-1 Antibody
- Antibody type
- Polyclonal
- Description
- Unpurified. This should cross-react with rat SOCS1, based on amino acid sequence.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.2 ml
- Concentration
- 0.5 mg/ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references SOCS-1 mediates ubiquitylation and degradation of GM-CSF receptor.
Loss of JAK2 regulation via a heterodimeric VHL-SOCS1 E3 ubiquitin ligase underlies Chuvash polycythemia.
IL-7 engages multiple mechanisms to overcome chronic viral infection and limit organ pathology.
SOCS1 regulates the IFN but not NFkappaB pathway in TLR-stimulated human monocytes and macrophages.
SOCS1 regulates the IFN but not NFkappaB pathway in TLR-stimulated human monocytes and macrophages.
Bunda S, Kommaraju K, Heir P, Ohh M
PloS one 2013;8(9):e76370
PloS one 2013;8(9):e76370
Loss of JAK2 regulation via a heterodimeric VHL-SOCS1 E3 ubiquitin ligase underlies Chuvash polycythemia.
Russell RC, Sufan RI, Zhou B, Heir P, Bunda S, Sybingco SS, Greer SN, Roche O, Heathcote SA, Chow VW, Boba LM, Richmond TD, Hickey MM, Barber DL, Cheresh DA, Simon MC, Irwin MS, Kim WY, Ohh M
Nature medicine 2011 Jun 19;17(7):845-53
Nature medicine 2011 Jun 19;17(7):845-53
IL-7 engages multiple mechanisms to overcome chronic viral infection and limit organ pathology.
Pellegrini M, Calzascia T, Toe JG, Preston SP, Lin AE, Elford AR, Shahinian A, Lang PA, Lang KS, Morre M, Assouline B, Lahl K, Sparwasser T, Tedder TF, Paik JH, DePinho RA, Basta S, Ohashi PS, Mak TW
Cell 2011 Feb 18;144(4):601-13
Cell 2011 Feb 18;144(4):601-13
SOCS1 regulates the IFN but not NFkappaB pathway in TLR-stimulated human monocytes and macrophages.
Prêle CM, Woodward EA, Bisley J, Keith-Magee A, Nicholson SE, Hart PH
Journal of immunology (Baltimore, Md. : 1950) 2008 Dec 1;181(11):8018-26
Journal of immunology (Baltimore, Md. : 1950) 2008 Dec 1;181(11):8018-26
SOCS1 regulates the IFN but not NFkappaB pathway in TLR-stimulated human monocytes and macrophages.
Prêle CM, Woodward EA, Bisley J, Keith-Magee A, Nicholson SE, Hart PH
Journal of immunology (Baltimore, Md. : 1950) 2008 Dec 1;181(11):8018-26
Journal of immunology (Baltimore, Md. : 1950) 2008 Dec 1;181(11):8018-26
No comments: Submit comment
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: SOCS-1 Antibody [NB100-56637] - Analysis of SOCS-1 using NB100-56637 at 1:1000 dilution against 15 ug/lane of Ramos (A) and Raw (B) cell lysate.
