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LearnBS2914
antibody from Bioworld Technology, Inc
Targeting: SOCS2
CIS2, Cish2, SOCS-2, SSI-2, SSI2, STATI2
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS2914 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- SOCS 2 (E67) polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide, corresponding to amino acids 41-90 of Human SOCS-2.
- Description
- SOCS2 is capable of inhibiting cytokine signalling by interleukin-6 (IL-6) and growth hormone. SOCS2 interacts with the phosphorylated insulin-like growth factor (IGF-I) receptor, where it may play a regulatory role in cellular growth, differentiation, and inhibition of apoptosis via the Ras and PI3K signalling pathways. In humans, SOCS2 mRNA is expressed widely in both foetal and adult tissues, including foetal kidney and adult heart, skeletal muscle, pancreas, and liver. In rats, SOCS2 mRNA exhibits high levels of expression in liver and heart, and in the mouse nervous system, SOCS2 is expressed exclusively by neurons, where it is switched on developmentally in concordance with neuronal differentiation.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot (WB) analysis of SOCS-2 (E67) pAb at 1:500 dilutionLane1:HEK293T whole cell lysateLane2:Raw264.7 whole cell lysateLane3:PC12 whole cell lysate
