Tissue expression
Cell line expression

SOCS2

gene product
CIS2, Cish2, SOCS-2, SSI-2, SSI2, STATI2 
This gene encodes a member of the suppressor of cytokine signaling (SOCS) family. SOCS family members are cytokine-inducible negative regulators of cytokine receptor signaling via the Janus kinase/signal transducer and activation of transcription pathway (the JAK/STAT pathway). SOCS family proteins interact with major molecules of signaling complexes to block further signal transduction, in part, by proteasomal depletion of receptors or signal-transducing proteins via ubiquitination. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10, interferon (IFN)-gamma and by cytokine receptors such as growth horomone receptor. The protein encoded by this gene interacts with the cytoplasmic domain of insulin-like growth factor-1 receptor (IGF1R) and is thought to be involved in the regulation of IGF1R mediated cell signaling. This gene has pseudogenes on chromosomes 20 and 22. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Antigen sequence

Conjugate

Epitope

Antibody

  or   Clear
Enhanced validation
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
294 antibodies from 36 providers.

Antibody properties

Applications

or Cancel
AntibodyRefsTypeWBELICCIPIHCFC
GeneTex
3 antibodies
OriGene
8 antibodies
antibodies-online
84 antibodies
Abnova Corporation
7 antibodies
Invitrogen Antibodies
7 antibodies
Boster Biological Technology
4 antibodies
Novus Biologicals
6 antibodies
Cell Signaling Technology, Inc
1 antibody
LifeSpan BioSciences, Inc.
61 antibodies
Cusabio Biotech Co., Ltd
7 antibodies
Abbkine Scientific Co.Ltd.
2 antibodies
Affinity Biosciences
1 antibody
HUABIO Research
1 antibody
NovoPro Bioscience Inc.
1 antibody
Biorbyt
19 antibodies
Santa Cruz Biotechnology
1 antibody
Acris Antibodies GmbH
4 antibodies
St John's Laboratory
3 antibodies
RabMAbs
2 antibodies
Arigo
2 antibodies
NSJ Bioreagents
2 antibodies
R&D Systems
2 antibodies
Bioss
2 antibodies
MyBioSource
5 antibodies
Aviva Systems Biology
2 antibodies
Bioworld Technology, Inc
1 antibody
Spring Bioscience
4 antibodies
Creative Biolabs
10 antibodies
RayBiotech, Inc.
2 antibodies
GenWay
1 antibody
Leading Biology
1 antibody
Abbexa
7 antibodies
United States Biological
25 antibodies
Creative Diagnostics
3 antibodies
MilliporeSigma / Merck KGaA
2 antibodies
Abgent
1 antibody