SOCS2

gene product
CIS2, Cish2, SOCS-2, SSI-2, SSI2, STATI2
This gene encodes a member of the suppressor of cytokine signaling (SOCS) family. SOCS family members are cytokine-inducible negative regulators of cytokine receptor signaling via the Janus kinase/signal transducer and activation of transcription pathway (the JAK/STAT pathway). SOCS family proteins interact with major molecules of signaling complexes to block further signal transduction, in part, by proteasomal depletion of receptors or signal-transducing proteins via ubiquitination. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10, interferon (IFN)-gamma and by cytokine receptors such as growth horomone receptor. The protein encoded by this gene interacts with the cytoplasmic domain of insulin-like growth factor-1 receptor (IGF1R) and is thought to be involved in the regulation of IGF1R mediated cell signaling. This gene has pseudogenes on chromosomes 20 and 22. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]
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204 antibodies from 33 providers.

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AntibodyRefsTypeAVIWBELICCIPIHCFC
GeneTex
3 antibodies
OriGene
8 antibodies
Novus Biologicals
6 antibodies
Abnova Corporation
7 antibodies
antibodies-online
49 antibodies
Cell Signaling Technology, Inc
1 antibody
LifeSpan BioSciences, Inc.
43 antibodies
Invitrogen Antibodies
4 antibodies
Abbkine Scientific Co.Ltd.
2 antibodies
Affinity Biosciences
1 antibody
NovoPro Bioscience Inc.
1 antibody
Biorbyt
13 antibodies
Santa Cruz Biotechnology
1 antibody
Bioss
1 antibody
Acris Antibodies GmbH
4 antibodies
St John's Laboratory
3 antibodies
RabMAbs
2 antibodies
Arigo
2 antibodies
NSJ Bioreagents
2 antibodies
R&D Systems
2 antibodies
Boster Biological Technology
2 antibodies
MyBioSource
5 antibodies
Aviva Systems Biology
2 antibodies
Bioworld Technology, Inc
1 antibody
Spring Bioscience
4 antibodies
RayBiotech, Inc.
2 antibodies
Creative Biolabs
1 antibody
GenWay
1 antibody
United States Biological
25 antibodies
Creative Diagnostics
1 antibody
Abbexa
3 antibodies
Abgent
1 antibody
Sigma-Aldrich
1 antibody