Antibody data
- Antibody Data
- Antigen structure
- References [15]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 55388-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#55388-1-AP, RRID:AB_10950890
- Product name
- PKA C-alpha specific antibody
- Antibody type
- Polyclonal
- Description
- PKA C-alpha specific antibody (Cat. #55388-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Achyranthes bidentata polysaccharide ameliorates type 2 diabetes mellitus by gut microbiota-derived short-chain fatty acids-induced activation of the GLP-1/GLP-1R/cAMP/PKA/CREB/INS pathway.
Prolonged exposure of environmental concentration benzo[a]pyrene promoted cancer stemness through AhR/PKA/SOX2 dependent pathway in small cell lung cancer.
Low-Dose Sodium Salicylate Promotes Ovulation by Regulating Steroids via CYP17A1.
Histone phosphorylation integrates the hepatic glucagon-PKA-CREB gluconeogenesis program in response to fasting.
Repeated Yueju, But Not Fluoxetine, Induced Sustained Antidepressant Activity in a Mouse Model of Chronic Learned Helplessness: Involvement of CaMKII Signaling in the Hippocampus.
Protein C receptor maintains cancer stem cell properties via activating lipid synthesis in nasopharyngeal carcinoma.
Quantitative proteomic analysis identified differentially expressed proteins with tail/rump fat deposition in Chinese thin- and fat-tailed lambs.
An Integrative Pharmacology-Based Strategy to Uncover the Mechanism of Xiong-Pi-Fang in Treating Coronary Heart Disease with Depression.
DA-DRD5 signaling controls colitis by regulating colonic M1/M2 macrophage polarization.
Rapid antidepressant-like effect of Fructus Aurantii depends on cAMP-response element binding protein/Brain-derived neurotrophic facto by mediating synaptic transmission.
Multi-chaperone function modulation and association with cytoskeletal proteins are key features of the function of AIP in the pituitary gland.
Bidirectional effects of moxifloxacin on the pro‑inflammatory response in lipopolysaccharide‑stimulated mouse peritoneal macrophages.
Label-Free Quantitative Phosphoproteomics Reveals Regulation of Vasodilator-Stimulated Phosphoprotein upon Stathmin-1 Silencing in a Pair of Isogenic Colorectal Cancer Cell Lines.
Neural Plasticity Associated with Hippocampal PKA-CREB and NMDA Signaling Is Involved in the Antidepressant Effect of Repeated Low Dose of Yueju Pill on Chronic Mouse Model of Learned Helplessness.
Increased Expression of Transient Receptor Potential Vanilloid 4 in Cortical Lesions of Patients with Focal Cortical Dysplasia.
Xia T, He W, Luo Z, Wang K, Tan X
International journal of biological macromolecules 2024 Jun;270(Pt 2):132256
International journal of biological macromolecules 2024 Jun;270(Pt 2):132256
Prolonged exposure of environmental concentration benzo[a]pyrene promoted cancer stemness through AhR/PKA/SOX2 dependent pathway in small cell lung cancer.
Ni H, Tang S, Yuan X, Xu J, Zheng F, Chen K, Liu X, Zhang H, Hu J, Xia D, Wu Y
The Science of the total environment 2024 Jan 1;906:167824
The Science of the total environment 2024 Jan 1;906:167824
Low-Dose Sodium Salicylate Promotes Ovulation by Regulating Steroids via CYP17A1.
Li T, Ren X, Li T, Yu L, Teng M, Zheng Y, Lei A
International journal of molecular sciences 2023 Jan 30;24(3)
International journal of molecular sciences 2023 Jan 30;24(3)
Histone phosphorylation integrates the hepatic glucagon-PKA-CREB gluconeogenesis program in response to fasting.
Zhao Y, Li S, Chen Y, Wang Y, Wei Y, Zhou T, Zhang Y, Yang Y, Chen L, Liu Y, Hu C, Zhou B, Ding Q
Molecular cell 2023 Apr 6;83(7):1093-1108.e8
Molecular cell 2023 Apr 6;83(7):1093-1108.e8
Repeated Yueju, But Not Fluoxetine, Induced Sustained Antidepressant Activity in a Mouse Model of Chronic Learned Helplessness: Involvement of CaMKII Signaling in the Hippocampus.
Zou Z, Huang J, Yang Q, Zhang Y, Xu B, Wang P, Chen G
Evidence-based complementary and alternative medicine : eCAM 2022;2022:1442578
Evidence-based complementary and alternative medicine : eCAM 2022;2022:1442578
Protein C receptor maintains cancer stem cell properties via activating lipid synthesis in nasopharyngeal carcinoma.
Zhang P, He Q, Wang Y, Zhou G, Chen Y, Tang L, Zhang Y, Hong X, Mao Y, He Q, Yang X, Liu N, Ma J
Signal transduction and targeted therapy 2022 Feb 16;7(1):46
Signal transduction and targeted therapy 2022 Feb 16;7(1):46
Quantitative proteomic analysis identified differentially expressed proteins with tail/rump fat deposition in Chinese thin- and fat-tailed lambs.
Han J, Guo T, Yue Y, Lu Z, Liu J, Yuan C, Niu C, Yang M, Yang B
PloS one 2021;16(2):e0246279
PloS one 2021;16(2):e0246279
An Integrative Pharmacology-Based Strategy to Uncover the Mechanism of Xiong-Pi-Fang in Treating Coronary Heart Disease with Depression.
Zhang L, Zhang Y, Zhu M, Pei L, Deng F, Chen J, Zhang S, Cong Z, Du W, Xiao X
Frontiers in pharmacology 2021;12:590602
Frontiers in pharmacology 2021;12:590602
DA-DRD5 signaling controls colitis by regulating colonic M1/M2 macrophage polarization.
Liu L, Wu Y, Wang B, Jiang Y, Lin L, Li X, Yang S
Cell death & disease 2021 May 17;12(6):500
Cell death & disease 2021 May 17;12(6):500
Rapid antidepressant-like effect of Fructus Aurantii depends on cAMP-response element binding protein/Brain-derived neurotrophic facto by mediating synaptic transmission.
Wu L, Zhang T, Chen K, Lu C, Liu XF, Zhou JL, Huang YK, Yan H, Chen Y, Zhang CJ, Li JF, Shi SQ, Ren P, Huang X
Phytotherapy research : PTR 2021 Jan;35(1):404-414
Phytotherapy research : PTR 2021 Jan;35(1):404-414
Multi-chaperone function modulation and association with cytoskeletal proteins are key features of the function of AIP in the pituitary gland.
Hernández-Ramírez LC, Morgan RML, Barry S, D'Acquisto F, Prodromou C, Korbonits M
Oncotarget 2018 Feb 6;9(10):9177-9198
Oncotarget 2018 Feb 6;9(10):9177-9198
Bidirectional effects of moxifloxacin on the pro‑inflammatory response in lipopolysaccharide‑stimulated mouse peritoneal macrophages.
Qiu Z, Yuan H, Li N, Yang X, Hu X, Su F, Chen B
Molecular medicine reports 2018 Dec;18(6):5399-5408
Molecular medicine reports 2018 Dec;18(6):5399-5408
Label-Free Quantitative Phosphoproteomics Reveals Regulation of Vasodilator-Stimulated Phosphoprotein upon Stathmin-1 Silencing in a Pair of Isogenic Colorectal Cancer Cell Lines.
Tan HT, Chung MCM
Proteomics 2018 Apr;18(8):e1700242
Proteomics 2018 Apr;18(8):e1700242
Neural Plasticity Associated with Hippocampal PKA-CREB and NMDA Signaling Is Involved in the Antidepressant Effect of Repeated Low Dose of Yueju Pill on Chronic Mouse Model of Learned Helplessness.
Zou Z, Chen Y, Shen Q, Guo X, Zhang Y, Chen G
Neural plasticity 2017;2017:9160515
Neural plasticity 2017;2017:9160515
Increased Expression of Transient Receptor Potential Vanilloid 4 in Cortical Lesions of Patients with Focal Cortical Dysplasia.
Chen X, Sun FJ, Wei YJ, Wang LK, Zang ZL, Chen B, Li S, Liu SY, Yang H
CNS neuroscience & therapeutics 2016 Apr;22(4):280-90
CNS neuroscience & therapeutics 2016 Apr;22(4):280-90
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human testis tissue were subjected to SDS PAGE followed by western blot with 55388-1-AP(PRKACA antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PRKACA antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human PRKACA. This antibody recognizes human, mouse antigen. The PRKACA antibody has been validated for the following applications: ELISA, WB, IHC analysis.