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TFAP2B
Transcription factor AP-2 betaAP2-B
This gene encodes a member of the AP-2 family of transcription factors. AP-2 proteins form homo- or hetero-dimers with other AP-2 family members and bind specific DNA sequences. They are thought to stimulate cell proliferation and suppress terminal differentiation of specific cell types during embryonic development. Specific AP-2 family members differ in their expression patterns and binding affinity for different promoters. This protein functions as both a transcriptional activator and repressor. Mutations in this gene result in autosomal dominant Char syndrome, suggesting that this gene functions in the differentiation of neural crest cell derivatives. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Proteintech Group |  13183-1-AP |
1 references | Polyclonal |
WB
EL
IP
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| antibodies-online | ABIN394169 |
5 references | Monoclonal |
WB
ICC
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| Santa Cruz Biotechnology | sc-8976 |
2 references | Polyclonal |
WB
IHC
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| Atlas Antibodies | HPA034683 |
2 references | Polyclonal |
IHC
ChIP
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| LSBio | LS-C198327 |
Monoclonal |
WB
EL
ICC
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