HPA034683

antibody from Atlas Antibodies

Targeting: TFAP2B AP2-B

Immunohistochemistry (Data presented on provider website)

Chromatin Immunoprecipitation (Supportive data in Antibodypedia)

Antibody Data

Product number

HPA034683

Provider

Atlas Antibodies

Proper citation

Atlas Antibodies Cat#HPA034683, RRID:AB_10670966

Product name

Anti-TFAP2B

Antibody type

Polyclonal

Description

Polyclonal Antibody against Human TFAP2B, Gene description: transcription factor AP-2 beta (activating enhancer binding protein 2 beta), Alternative Gene Names: AP2-B, Validated applications: IHC, ChIP, Uniprot ID: Q92481, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

0.1 mg/ml

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling

The antibody solution should be gently mixed before use.

References

Submitted references

Transcription factors AP-2α and AP-2β regulate distinct segments of the distal nephron in the mammalian kidney.

Lamontagne JO, Zhang H, Zeid AM, Strittmatter K, Rocha AD, Williams T, Zhang S, Marneros AG
Nature communications 2022 Apr 25;13(1):2226

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Sleep Architecture in Mice Is Shaped by the Transcription Factor AP-2β.

Nakai A, Fujiyama T, Nagata N, Kashiwagi M, Ikkyu A, Takagi M, Tatsuzawa C, Tanaka K, Kakizaki M, Kanuka M, Kawano T, Mizuno S, Sugiyama F, Takahashi S, Funato H, Sakurai T, Yanagisawa M, Hayashi Y
Genetics 2020 Nov;216(3):753-764

Chromatin Immunoprecipitation

Supportive validation

Submitted by

Atlas Antibodies (provider)

Main image

Experimental details

ChIP-Exo-Seq composite graph for Anti-TFAP2B (HPA034683, Lot 000009221) tested in K562 cells. Strand-specific reads (blue: forward, red: reverse) and IgG controls (black: forward, grey: reverse) are plotted against the distance from a composite set of reference binding sites. The antibody exhibits robust target enrichment compared to a non-specific IgG control and precisely reveals its structural organization around the binding site. Data generated by Prof. B. F. Pugh´s Lab at Cornell University.