BS5064

antibody from Bioworld Technology, Inc

Targeting: CRK

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

BS5064

Provider

Bioworld Technology, Inc

Proper citation

Bioworld Technology Cat#BS5064, RRID:AB_1661859

Product name

Crk2 (phospho Try221) polyclonal antibody

Antibody type

Polyclonal

Antigen

Synthetic phosphopeptide derived from human Crk2 around the phosphorylation site of Tyrosine 221.

Description

Crk I and Crk II are encoded by the same gene, which undergoes alternative splicing to yield these two proteins, but differ in their biological activities. Crk II has less transforming activity than Crk I, although both Crk I and Crk II bind to many tyrosine-phosphorylated proteins that bind to GRB2. In addition, Crk II becomes rapidly tyrosine-phosphorylated in response to stimulation with insulin-like growth factor I (IGF-I) and might be involved in the IGF-I receptor signalling pathway.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Isotype

IgG

Vial size

100ul

Concentration

1 mg/ml

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.