CRK

gene product
This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described. [provided by RefSeq, Jul 2008]
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antibodies-online
208 antibodies
Abnova Corporation
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Invitrogen Antibodies
9 antibodies
GeneTex
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OriGene
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LifeSpan BioSciences, Inc.
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Proteintech Group
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Aviva Systems Biology
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Affinity Biosciences
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Abgent
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Bioworld Technology, Inc
4 antibodies
NSJ Bioreagents
2 antibodies
Santa Cruz Biotechnology
1 antibody
Cell Signaling Technology, Inc
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Boster Biological Technology
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RabMAbs
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Abbkine Scientific Co.Ltd.
2 antibodies
NovoPro Bioscience Inc.
4 antibodies
Creative Biolabs
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Creative Diagnostics
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R&D Systems
2 antibodies
Arigo
1 antibody
Atlas Antibodies
1 antibody
United States Biological
74 antibodies
Abiocode, Inc.
2 antibodies
MyBioSource
13 antibodies
EMD Millipore
1 antibody
Sigma-Aldrich
2 antibodies
GenWay
1 antibody
Leading Biology
1 antibody