CRK

gene product
This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described. [provided by RefSeq, Jul 2008]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

  or   Clear
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Validated within AVI
Eligible for validation within AVI
571 antibodies from 34 providers.

Antibody properties

General

Applications

or Cancel
AntibodyRefsTypeWBELICCIPIHCFC
antibodies-online
208 antibodies
Abnova Corporation
10 antibodies
Novus Biologicals
8 antibodies
GeneTex
9 antibodies
Acris Antibodies GmbH
13 antibodies
OriGene
10 antibodies
Biorbyt
30 antibodies
LifeSpan BioSciences, Inc.
65 antibodies
Invitrogen Antibodies
7 antibodies
Aviva Systems Biology
3 antibodies
St John's Laboratory
10 antibodies
Affinity Biosciences
3 antibodies
Abgent
6 antibodies
Bioworld Technology, Inc
4 antibodies
NSJ Bioreagents
2 antibodies
Santa Cruz Biotechnology
1 antibody
Cell Signaling Technology, Inc
2 antibodies
Boster Biological Technology
2 antibodies
RabMAbs
7 antibodies
Abbkine Scientific Co.Ltd.
2 antibodies
NovoPro Bioscience Inc.
4 antibodies
Creative Biolabs
23 antibodies
Creative Diagnostics
8 antibodies
Proteintech Group
1 antibody
R&D Systems
2 antibodies
Arigo
1 antibody
Atlas Antibodies
1 antibody
United States Biological
74 antibodies
Abiocode, Inc.
2 antibodies
MyBioSource
13 antibodies
EMD Millipore
1 antibody
Sigma-Aldrich
2 antibodies
GenWay
1 antibody