orb1726924

antibody from Biorbyt
Targeting: CRK
Provider product page for orb1726924
Western blot
Immunocytochemistry
Immunoprecipitation
Flow cytometry

Antibody data

Product number
orb1726924 - Provider product page
Provider
Biorbyt
Product name
CRKII Rabbit mAb [KD Validated]
Antibody type
Recombinant
Description
The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk-II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Conjugate
Unconjugated
Vial size
50 ul
Storage
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
CRK protein structure - orb1726924 shown in red.