Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [1]
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- Product number
- ABIN2841625 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Cyclin-Dependent Kinase 4 (CDK4) (AA 273-305), (C-Term) antibody
- Antibody type
- Polyclonal
- Description
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- AA 273-305, C-Term
- Antibody clone number
- RB03154
- Vial size
- 80 μL
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Submitted references Brk/Protein tyrosine kinase 6 phosphorylates p27KIP1, regulating the activity of cyclin D-cyclin-dependent kinase 4.
Bypass of telomere-dependent replicative senescence (M1) upon overexpression of Cdk4 in normal human epithelial cells.
Absence of R24C mutation of the CDK4 gene in leukemias and solid tumors.
Patel P, Asbach B, Shteyn E, Gomez C, Coltoff A, Bhuyan S, Tyner AL, Wagner R, Blain SW
Molecular and cellular biology 2015 May;35(9):1506-22
Molecular and cellular biology 2015 May;35(9):1506-22
Bypass of telomere-dependent replicative senescence (M1) upon overexpression of Cdk4 in normal human epithelial cells.
Ramirez RD, Herbert BS, Vaughan MB, Zou Y, Gandia K, Morales CP, Wright WE, Shay JW
Oncogene 2003 Jan 23;22(3):433-44
Oncogene 2003 Jan 23;22(3):433-44
Absence of R24C mutation of the CDK4 gene in leukemias and solid tumors.
Mori N, Yang R, Kawamata N, Miller CW, Mizoguchi H, Koeffler HP
International journal of hematology 2003 Apr;77(3):259-62
International journal of hematology 2003 Apr;77(3):259-62
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Supportive validation
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- antibodies-online (provider)
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- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC