CABT-L669

antibody from Creative Diagnostics

Targeting: CDK4 PSK-J3

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

CABT-L669

Provider

Creative Diagnostics

Product name

Rabbit Anti-ARB1 monoclonal antibody, clone TU62-19

Antibody type

Monoclonal

Description

The members of the G protein coupled receptor family are distinguished by their slow transmitting response to ligand binding. These seven transmembrane proteins include the adrenergic, serotonin and dopamine receptors. The effect of the signaling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. Members of theÉÇ-Arrestin family regulate receptor binding to G proteins. ÉÇ-Arrestins have been found to be located at postsynaptic sites, where they are thought to act in concert withÉÇARK (ÉÇARK1, also designated GRK 2, orÉÇARK2, also designated GRK 3 to regulate G protein-coupled neurotransmitter receptors. Expression ofÉÇ-Arrestin-1 and b-Arrestin-2 is seen predominantly in spleen and neuronal tissues. It has been shown thatÉÇ-Arrestin-1 expression is modulated by intracellular cAMP, which may be a novel mechanism for the regulation of receptor-mediated responses.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

TU62-19

Vial size

100 _l

Storage

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.