Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- ABIN1882291 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Vaccinia Related Kinase 1 (VRK1) (Center) antibody
- Antibody type
- Monoclonal
- Antigen
- Purified His-tagged VRK1 protein was used to produced this monoclonal antibody.
- Description
- Ascites
- Reactivity
- Human
- Host
- Mouse
- Epitope
- Center
- Isotype
- IgG
- Antibody clone number
- 1015CT2-1-1
- Vial size
- 100 μL
Submitted references The subcellular localization of vaccinia-related kinase-2 (VRK2) isoforms determines their different effect on p53 stability in tumour cell lines.
Characterization of three paralogous members of the Mammalian vaccinia related kinase family.
Kinetic properties of p53 phosphorylation by the human vaccinia-related kinase 1.
The human vaccinia-related kinase 1 (VRK1) phosphorylates threonine-18 within the mdm-2 binding site of the p53 tumour suppressor protein.
Blanco S, Klimcakova L, Vega FM, Lazo PA
The FEBS journal 2006 Jun;273(11):2487-504
The FEBS journal 2006 Jun;273(11):2487-504
Characterization of three paralogous members of the Mammalian vaccinia related kinase family.
Nichols RJ, Traktman P
The Journal of biological chemistry 2004 Feb 27;279(9):7934-46
The Journal of biological chemistry 2004 Feb 27;279(9):7934-46
Kinetic properties of p53 phosphorylation by the human vaccinia-related kinase 1.
Barcia R, López-Borges S, Vega FM, Lazo PA
Archives of biochemistry and biophysics 2002 Mar 1;399(1):1-5
Archives of biochemistry and biophysics 2002 Mar 1;399(1):1-5
The human vaccinia-related kinase 1 (VRK1) phosphorylates threonine-18 within the mdm-2 binding site of the p53 tumour suppressor protein.
Lopez-Borges S, Lazo PA
Oncogene 2000 Jul 27;19(32):3656-64
Oncogene 2000 Jul 27;19(32):3656-64
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- VRK1 Antibody (Center) (ABIN1882291) western blot analysis in Hela,HL-60 cell line lysates (35 μg/lane). This demonstrates the VRK1 antibody detected the VRK1 protein (arrow).