Tissue expression
Cell line expression
Protein structure
VRK1
VRK serine/threonine kinase 1This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN. [provided by RefSeq, Jul 2008]
Top validated antibodies |
|||||
Atlas Antibodies | HPA000660 | 6 references | Polyclonal |
WB
ICC
IHC
|
|
LSBio | LS-C198432 | Monoclonal |
WB
EL
ICC
IP |
||
Novus Biologicals | NBP1-85822 | 6 references | Polyclonal |
WB
ICC
IHC
|
|
Abnova Corporation | H00007443-M02 | Monoclonal |
WB
EL
ICC
IP |
||
antibodies-online | ABIN521352 | Monoclonal |
WB
EL
ICC
IP |
All Antibodies
Filters
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider