CD5

This gene encodes a member of the scavenger receptor cysteine-rich (SRCR) superfamily. Members of this family are secreted or membrane-anchored proteins mainly found in cells associated with the immune system. This protein is a type-I transmembrane glycoprotein found on the surface of thymocytes, T lymphocytes and a subset of B lymphocytes. The encoded protein contains three SRCR domains and may act as a receptor to regulate T-cell proliferation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2016]

Description

CD5 molecule

Protein family

CD markers, Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Predicted intracellular proteins, Predicted membrane proteins, Protein evidence (Peptideatlas)

Chromosome

11:q12.2 (61102489 - 61127852)

Ensembl ID

ENSG00000110448  (ver. 99.38)

Orthologs

Mouse Cd5: ENSMUSG00000024669

UniProt

P06127

neXtProt

NX_P06127

Human splice variants
Mouse splice variants