ABIN1673386

antibody from antibodies-online

Targeting: CYP1A2 CP12, P3-450

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN1673386

Provider

antibodies-online

Product name

anti-Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2) (Middle Region) antibody

Antibody type

Polyclonal

Antigen

A synthetic peptide corresponding to a sequence in the middle region of human CYP1A2, different from the related rat and mouse sequences by three amino acids.Immunogen affinity purified.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

Middle Region

Isotype

IgG

Vial size

100 μg

Storage

At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

CYP1A2 is more variable than previously thought: a genomic biography of the gene behind the human drug-metabolizing enzyme.

Browning SL, Tarekegn A, Bekele E, Bradman N, Thomas MG
Pharmacogenetics and genomics 2010 Nov;20(11):647-64

---

Genetic polymorphism in the 5'-flanking region of human CYP1A2 gene: effect on the CYP1A2 inducibility in humans.

Nakajima M, Yokoi T, Mizutani M, Kinoshita M, Funayama M, Kamataki T
Journal of biochemistry 1999 Apr;125(4):803-8

---

Human CYP1A2: sequence, gene structure, comparison with the mouse and rat orthologous gene, and differences in liver 1A2 mRNA expression.

Ikeya K, Jaiswal AK, Owens RA, Jones JE, Nebert DW, Kimura S
Molecular endocrinology (Baltimore, Md.) 1989 Sep;3(9):1399-408