CYP1A2

gene product
CP12, P3-450
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region. [provided by RefSeq, Jul 2008]
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Antibodies

 

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Antibodypedia Validation Initiative

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627 antibodies from 34 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
antibodies-online
207 antibodies
NovoPro Bioscience Inc.
3 antibodies
OriGene
47 antibodies
GeneTex
10 antibodies
Novus Biologicals
46 antibodies
Biorbyt
24 antibodies
NSJ Bioreagents
6 antibodies
Acris Antibodies GmbH
5 antibodies
Abgent
3 antibodies
Proteintech Group
1 antibody
Invitrogen Antibodies
3 antibodies
LifeSpan BioSciences, Inc.
88 antibodies
Boster Biological Technology
3 antibodies
Aviva Systems Biology
5 antibodies
Affinity Biosciences
1 antibody
Abnova Corporation
11 antibodies
Santa Cruz Biotechnology
2 antibodies
ProSci
2 antibodies
Antibodies.com
1 antibody
MyBioSource
15 antibodies
United States Biological
91 antibodies
Creative Diagnostics
15 antibodies
Creative Biolabs
5 antibodies
St John's Laboratory
3 antibodies
Exalpha Biologicals, Inc.
2 antibodies
Cell Signaling Technology, Inc
1 antibody
RabMAbs
1 antibody
RayBiotech, Inc.
1 antibody
Enzo Life Sciences
4 antibodies
GenWay
5 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
EMD Millipore
1 antibody
Sigma-Aldrich
2 antibodies