Tissue expression
Cell line expression
Protein structure

CYP1A2

Cytochrome P450 family 1 subfamily A member 2
CP12, P3-450 
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region. [provided by RefSeq, Jul 2008]
More gene data

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809 antibodies from 38 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
Proteintech Group
1 antibody
Invitrogen Antibodies
45 antibodies
antibodies-online
207 antibodies
NovoPro Bioscience Inc.
3 antibodies
OriGene
60 antibodies
GeneTex
10 antibodies
Novus Biologicals
60 antibodies
Wuhan Fine Biotech Co., Ltd.
1 antibody
Biorbyt
47 antibodies
NSJ Bioreagents
8 antibodies
Exalpha Biologicals, Inc.
2 antibodies
Acris Antibodies GmbH
5 antibodies
Abgent
3 antibodies
Boster Biological Technology
4 antibodies
St John's Laboratory
4 antibodies
Cusabio Biotech Co., Ltd
9 antibodies
Aviva Systems Biology
5 antibodies
Affinity Biosciences
1 antibody
Abnova Corporation
11 antibodies
Santa Cruz Biotechnology
2 antibodies
ProSci
2 antibodies
Antibodies.com
1 antibody
Creative Biolabs
49 antibodies
MyBioSource
15 antibodies
United States Biological
91 antibodies
Abbexa
13 antibodies
Creative Diagnostics
15 antibodies
Cell Signaling Technology, Inc
1 antibody
RabMAbs
1 antibody
RayBiotech, Inc.
1 antibody
Enzo Life Sciences
4 antibodies
GenWay
5 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
EMD Millipore
1 antibody
Leading Biology
2 antibodies
MilliporeSigma / Merck KGaA
2 antibodies