CABT-BL8389

antibody from Creative Diagnostics
Targeting: TNFRSF4 ACT35, CD134, OX40, TXGP1L
Provider product page for CABT-BL8389
Flow cytometry

Antibody data

Product number
CABT-BL8389 - Provider product page
Provider
Creative Diagnostics
Product name
Anti-TNFRSF4 Monoclonal antibody, clone PY-97 [APC]
Antibody type
Monoclonal
Description
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation.
Reactivity
Mouse
Host
Rat
Isotype
IgG
TNFRSF4 protein structure - CABT-BL8389 shown in red.