Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations [0]
Submit
Validation data
Reference
Comment
Report error
- Product number
- CABT-BL8389 - Provider product page
- Provider
- Creative Diagnostics
- Product name
- Anti-TNFRSF4 Monoclonal antibody, clone PY-97 [APC]
- Antibody type
- Monoclonal
- Description
- The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation.
- Reactivity
- Mouse
- Host
- Rat
- Isotype
- IgG
No comments: Submit comment
No validations: Submit validation data