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Protein structure
TNFRSF4
TNF receptor superfamily member 4ACT35, CD134, OX40, TXGP1L
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Invitrogen Antibodies |  A700-042 |
Monoclonal |
WB
ICC
IP
IHC
FC
OA
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| GeneTex | GTX42439 |
13 references | Monoclonal |
IP
IHC
FC
|
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| Novus Biologicals | NBP2-62202 |
Monoclonal |
WB
EL
IP
IHC
FC
|
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| R&D Systems | AF3388 |
Polyclonal |
WB
IHC
FC
BN
|
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| LSBio | LS-C815498 |
Polyclonal |
WB
IP
|
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