350001

antibody from BioLegend

Targeting: TNFRSF4 ACT35, CD134, OX40, TXGP1L

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

350001

Provider

BioLegend

Proper citation

BioLegend Cat#350001, RRID:AB_10645523

Product name

Purified anti-human CD134 (OX40)

Antibody type

Monoclonal

Antigen

HTLV 1-transformed HUT 102 cells

Description

CD134, also known as OX40 and TNFRSF14, is a 50 kD type I transmembrane glycoprotein. It is a member of the TNF receptor family. OX40 is expressed on activated T lymphocytes including Th1, Th2, Th17, and Treg cells. The interaction of OX40 with OX40L results in B cell proliferation and antibody secretion, regulation of primary T cell expansion, and T cell survival. OX40 influences the size of the T cell memory pool and regulation of CD4+ T cell tolerance.

Reactivity

Human, Simian

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Vial size

25 µg

Concentration

0.5 mg/ml

Storage

The antibody solution should be stored undiluted at 4°C.