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Western blot
Flow cytometryAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Flow cytometry [1]
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- Product number
- 350002 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#350002, RRID:AB_10639951
- Product name
- Purified anti-human CD134 (OX40)
- Antibody type
- Monoclonal
- Antigen
- HTLV 1-transformed HUT 102 cells
- Description
- CD134, also known as OX40 and TNFRSF14, is a 50 kD type I transmembrane glycoprotein. It is a member of the TNF receptor family. OX40 is expressed on activated T lymphocytes including Th1, Th2, Th17, and Treg cells. The interaction of OX40 with OX40L results in B cell proliferation and antibody secretion, regulation of primary T cell expansion, and T cell survival. OX40 influences the size of the T cell memory pool and regulation of CD4+ T cell tolerance.
- Reactivity
- Human, Simian
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- The antibody solution should be stored undiluted at 4°C.
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Supportive validation
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- BioLegend (provider)
- Main image
- Experimental details
- PHA-stimulated (3 days) human peripheral blood lymphocytes were stained with purified OX-40 (clone Ber-ACT35, filled histogram) or purified mouse IgG1, κ isotype control (open histogram), followed by anti-mouse IgG PE.
- Conjugate
- Unconjugated
